Page last updated: 2024-09-04

atrasentan and 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide

atrasentan has been researched along with 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide in 1 studies

Compound Research Comparison

Studies
(atrasentan)
Trials
(atrasentan)
Recent Studies (post-2010)
(atrasentan)
Studies
(5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)
Trials
(5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)
Recent Studies (post-2010) (5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide)
358411087308

Protein Interaction Comparison

ProteinTaxonomyatrasentan (IC50)5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide (IC50)
Endothelin-1 receptorHomo sapiens (human)0.23
Endothelin-1 receptorRattus norvegicus (Norway rat)0.015

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bal, R; Boyd, SA; Chiou, WJ; Dixon, DB; Hernandez, L; Jae, HS; Kester, JA; Mantei, RA; Marsh, KC; Novosad, EI; Opgenorth, TJ; Sorensen, BK; Tasker, AS; von Geldern, TW; Winn, M; Wu-Wong, JR1

Other Studies

1 other study(ies) available for atrasentan and 5-(dimethylamino)-n-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide

ArticleYear
2,4-Diarylpyrrolidine-3-carboxylic acids--potent ETA selective endothelin receptor antagonists. 1. Discovery of A-127722.
    Journal of medicinal chemistry, 1996, Mar-01, Volume: 39, Issue:5

    Topics: Animals; Aorta; Atrasentan; Biological Availability; Endothelin Receptor Antagonists; Endothelins; Hydrolysis; Male; Molecular Structure; Phosphatidylinositols; Pyrrolidines; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Structure-Activity Relationship; Vasoconstriction

1996