atractyloside and cumene-hydroperoxide

atractyloside has been researched along with cumene-hydroperoxide* in 1 studies

Other Studies

1 other study(ies) available for atractyloside and cumene-hydroperoxide

Article	Year
Effects of the membrane potential upon the Ca(2+)- and cumene hydroperoxide-induced permeabilization of the inner mitochondrial membrane. FEBS letters, 1991, Dec-16, Volume: 295, Issue:1-3 A protonophore-induced delta psi decrease in a 180-140 mV range causes an increase in the lag-period of Ca(2+)-induced mitochondrial permeabilization but has little effect on the cumene hydroperoxide-induced permeability transition of mitochondria. Suppression of the non-specific permeability induction seems to be mediated by an increase in [ADP] in the mitochondrial matrix. A further decrease in delta psi leads to additional suppression of the non-specific permeability as a result of a partial ruthenium red-sensitive efflux of the previously accumulated Ca2+. On the other hand, complete dissipation of delta psi causes immediate induction of the non-specific permeability. It is concluded that only complete dissipation of delta psi caused by H+ leakages may act as a trigger for non-specific permeability induction. Topics: Animals; Atractyloside; Benzene Derivatives; Calcium Chloride; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Intracellular Membranes; Kinetics; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Permeability; Rats; Ruthenium Red; Submitochondrial Particles	1991

Article

Year

Effects of the membrane potential upon the Ca(2+)- and cumene hydroperoxide-induced permeabilization of the inner mitochondrial membrane.

FEBS letters, 1991, Dec-16, Volume: 295, Issue:1-3

A protonophore-induced delta psi decrease in a 180-140 mV range causes an increase in the lag-period of Ca(2+)-induced mitochondrial permeabilization but has little effect on the cumene hydroperoxide-induced permeability transition of mitochondria. Suppression of the non-specific permeability induction seems to be mediated by an increase in [ADP] in the mitochondrial matrix. A further decrease in delta psi leads to additional suppression of the non-specific permeability as a result of a partial ruthenium red-sensitive efflux of the previously accumulated Ca2+. On the other hand, complete dissipation of delta psi causes immediate induction of the non-specific permeability. It is concluded that only complete dissipation of delta psi caused by H+ leakages may act as a trigger for non-specific permeability induction.

Topics: Animals; Atractyloside; Benzene Derivatives; Calcium Chloride; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Intracellular Membranes; Kinetics; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Permeability; Rats; Ruthenium Red; Submitochondrial Particles

1991