Page last updated: 2024-09-04

atractylenolide iii and sesquiterpenes

atractylenolide iii has been researched along with sesquiterpenes in 71 studies

Compound Research Comparison

Studies (atractylenolide iii)	Trials (atractylenolide iii)	Recent Studies (post-2010) (atractylenolide iii)	Studies (sesquiterpenes)	Trials (sesquiterpenes)	Recent Studies (post-2010) (sesquiterpenes)
86	0	62	17,489	536	7,668

Research

Studies (71)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (2.82)	18.2507
2000's	15 (21.13)	29.6817
2010's	37 (52.11)	24.3611
2020's	17 (23.94)	2.80

Authors

Authors	Studies
Li, W; Qiu, L; Wen, H; Wu, H	1
Lai, YR; Li, Q; Lin, YC; Xu, SB; Zhang, X; Zhang, YQ	1
Chen, LG; Wang, CC; Yang, LL	1
Lin, Y; Xu, S; Zhang, Y	1
Hashimoto, A; Kuwahara, Y; Nakamura, T; Nishi, H	1
Hao, H; Wang, G; Wang, R; Wu, F; Xie, H; Zhang, J	1
Cheng, HC; Hou, WC; Lin, SY; Wang, CC	1
Lu, SY; Qian, JQ; Zou, XM	1
Deng, T; He, LC; Li, CQ	1
Cui, XB; Li, W; Wen, HM; Zhang, KW	1
He, LC; Jin, JQ; Li, CQ	1
Ge, J; Gong, FJ; Lu, XC; Sun, XH; Wang, YW	1
Ahn, YJ; Kim, HK; Yun, YK	1
Dong, H; Dong, Y; He, L; Huang, M	1
Dai, S; Li, H; Shou, D; Yu, Z; Zhang, J	1
Gan, LS; Li, XH; Liu, X; Mo, JX; Zheng, YL; Zhou, CX	1
Ohama, T; Park, HS	1
Chang, CC; Chen, LG; Wang, CC; Wang, KT; Wu, CH	1
Bae, H; Hong, MH; Kim, JH; Kim, SH; Ko, SG; Lee, NY; Shin, YC	1
Bang, JY; Jeong, HJ; Kang, IC; Kang, TH; Kim, HM; Kim, MH	1
Han, NR; Jeong, HJ; Kang, TH; Kim, HM	1
Liu, Y; Qi, HY; Shi, YP; Wang, R	1
Gao, N; Lin, H; Rong, S	1
Guan, SH; Guo, DA; Shi, YY; Tang, RN; Tao, SJ	1
Qu, F; Yu, Y; Zhou, J	1
Chen, DF; Deng, RD; Li, H; Li, X; Li, YW; Liu, DH; Wang, X; Wei, G; Zeng, HP; Zhou, JH	1
Park, DK; Park, HJ; Zhang, NN	1
Chen, Q; He, H; Li, P; Xiong, M; Zhu, J	1
Cui, HY; Jiang, P; Liu, CH; Liu, P; Ma, YM; Shi, R; Wang, Q; Zhong, J	1
Cui, XB; Li, W; Shan, CX; Wen, HM; Wu, H	1
Guo, HP; Hu, RH; Shao, QS; Ye, WW; Zhang, AL	1
Jia, TZ; Jiang, H; Shan, GS; Xiao, HB; Xu, G; You, XM; Zhang, LX; Zhao, QM; Zhuo, RJ	1
Ji, ZH; Liu, C; Yu, XY; Zhao, H	2
Sun, Y; Wang, X; Wang, Y; Yan, H; Yang, M; Yu, Z; Zhang, Q; Zhao, Y	1
Cai, R; Fu, J; Ke, X; Liu, T; Lu, H; Ma, J; Wang, S	1
Cao, YF; Dong, PP; Hu, CM; Li, RS; Ran, RX; Wang, WM; Wu, X; Zhang, Q; Zhang, YY	1
Fu, J; Ke, X; Liu, T; Lu, H; Ma, J; Tan, S; Wang, S	1
Chen, RQ; Ji, GQ; Wang, L	1
Cho, HD; Choi, YS; Eom, HY; Han, SB; Kim, J; Kim, U; Lee, SG; Suh, JH	1
Gao, L; Gao, XX; Gao, Y; Qin, XM; Tian, JS; Zhou, YZ	1
Dou, DQ; Kang, TG; Liu, C; Ran, XK; Sun, TM; Zhang, N	1
Jung, HW; Kang, SY; Park, YK; Song, MY	1
Choi, IH; Jang, JB; Jeong, HJ; Jin, MH; Kim, DH; Kim, HM; Kim, MS; Lee, SY; Lim, S; Nam, SY; Roh, SS; Woo, N; Yoou, MS	1
Qin, XM; Shen, XL; Tian, JS; Xu, WH; Zhao, YJ	1
Feng, Y; Huang, W; Jiang, Z; Ouyang, H; Peng, C; Wu, B; Yang, S; Zhang, D	1
Cai, Q; Liu, Y; Lv, X; Qi, X; Sun, J; Xu, S	1
Feng, Q; Gao, JP; Ji, JJ; Li, JK; Li, XX; Sun, HF; Zhang, XJ	1
Chen, J; Chen, L; Jia, C; Jiang, S; Kong, J; Kou, J; Tu, W; Wu, J; Wu, Q; Xu, YXZ; Yang, G; Zhou, K	1
Dai, Y; Hu, L; Kiyohara, H; Liu, L; Qin, Z; Song, X; Yamada, H; Yao, X; Yao, Z	1
DU, GH; Gong, WX; Qin, XM; Zhou, YZ	1
Hu, R; Liu, L; Lu, L; Pei, T; Wang, F; Wang, M; Wang, Y; Wei, L; Wu, X; Xiao, W; You, H; Zhang, J	1
Go, Y; Jeong, YH; Li, W; Oh, YC	1
Chen, Y; Guo, Q; Ji, Y; Kang, N; Kang, Z; Zhao, Y	1
Hayashi, F; Kawagishi, H; Kobayashi, K; Nur, EAA; Ohshiro, T; Tomoda, H; Wahyudin, E; Wu, J; Zhang, H	1
Bai, Y; Li, C; Liu, Z; Wang, L; Zhang, L; Zhu, C	1
Ding, J; Huai, B	1
Chen, G; Chen, S; Hu, P; Luo, Y; Tan, S; Tang, K; Yang, C; Yang, S; Zou, H	1
Chen, Z; Gong, L; Li, J; Li, N; Li, X; Liu, L; Luo, H; Sheng, L; Zhang, Q	1
Jiang, D; Li, Z; Yi, H; Zhang, L	1
Huang, S; Jian, X; Luo, Y; Wu, F; Zhang, F; Zheng, Q; Zhou, Y	1
Huang, M; Jiang, W; Luo, C; Ren, Y; Zhang, X	1
Cao, S; Chen, S; Li, X; Liu, M; Song, D; Zhang, D; Zhang, Z	1
Chen, H; Deng, M; Li, X; Long, J; Song, J; Xie, L	1
Wang, Z; Yin, L; Yu, J; Zhu, A; Zhu, S	1
Fu, JD; Gao, CH; Li, SC; Li, SW; Tian, Y; Wei, YE; Xian, LW	1
Huang, M; Jiang, W; Luo, C; Ren, Y; Yang, M	1
Chen, F; Lin, W	1
Geng, ZJ; Hu, JG; Lü, HZ; Shen, L; Sheng, WJ; Shi, YJ; Song, X; Wang, R; Xue, MT	1
Cui, YL; Gao, H; Hu, B; Huang, Y; Li, X; Liang, X; Liu, WW; Liu, X; Ma, Q; Wang, N; Wu, Q; Zhao, QC; Zhou, LJ	1
Chen, J; Ding, R; Gu, JF; Huang, JL; Li, XY; Tang, TJ; Wang, L; Wang, X; Yao, J; Zhou, P; Zuo, MY	1

Reviews

1 review(s) available for atractylenolide iii and sesquiterpenes

Article	Year
Atractylenolides (I, II, and III): a review of their pharmacology and pharmacokinetics. Archives of pharmacal research, 2021, Volume: 44, Issue:7 Topics: Animals; Atractylodes; Disease Models, Animal; Humans; Inflammation; Lactones; Medicine, Chinese Traditional; Mice; Neoplasms; Nervous System Diseases; Rhizome; Sesquiterpenes	2021

Other Studies

70 other study(ies) available for atractylenolide iii and sesquiterpenes

Article	Year
[Influence of processing on atractylenolide III content in Atractylodes macrocephala Koids]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1997, Volume: 22, Issue:11 Topics: Asteraceae; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Hot Temperature; Lactones; Plants, Medicinal; Sesquiterpenes; Technology, Pharmaceutical	1997
Antagonistic effects of 3 sesquiterpene lactones from Atractylodes macrocephala Koidz on rat uterine contraction in vitro. Acta pharmacologica Sinica, 2000, Volume: 21, Issue:1 Topics: Acetylcholine; Animals; Biological Transport, Active; Calcium; Cholinergic Antagonists; Drugs, Chinese Herbal; Female; In Vitro Techniques; Lactones; Oxytocin; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Uterine Contraction	2000
Cytotoxic activity of sesquiterpenoids from Atractylodes ovata on leukemia cell lines. Planta medica, 2002, Volume: 68, Issue:3 Topics: Animals; Asteraceae; Blotting, Western; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Lactones; Medicine, Chinese Traditional; Plant Extracts; Plant Structures; Proteins; Sesquiterpenes; Tumor Cells, Cultured	2002
[Gastrointestinal inhibitory effects of sesquiterpene lactones from Atractylodes macrocephala]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 1999, Volume: 22, Issue:12 Topics: Animals; Atractylodes; Cholinergic Antagonists; Gastrointestinal Motility; Ileum; Lactones; Male; Mice; Muscle Contraction; Muscle, Smooth; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rhizome; Sesquiterpenes	1999
[Analysis of natural medicines by micellar electrokinetic chromatography (MEKC) (II)--determination of atractylenolide III in Atractylodis Rhizoma]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2003, Volume: 123, Issue:6 Topics: Chromatography, Micellar Electrokinetic Capillary; Drugs, Chinese Herbal; Lactones; Plants, Medicinal; Quality Control; Sesquiterpenes	2003
Quantitative determination of atractylenolide III in rat plasma by liquid chromatography electrospray ionization mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Feb-02, Volume: 831, Issue:1-2 Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Lactones; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization	2006
Pro-oxidant and cytotoxic activities of atractylenolide I in human promyeloleukemic HL-60 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2006, Volume: 44, Issue:8 Topics: Apoptosis; Asteraceae; Cell Survival; DNA Fragmentation; Drug Interactions; Electron Spin Resonance Spectroscopy; Flow Cytometry; Free Radical Scavengers; HL-60 Cells; Humans; Hydrogen Peroxide; Hydroxyl Radical; Inhibitory Concentration 50; Iron; Lactones; Peroxides; Recombinant Proteins; Rhizome; Sesquiterpenes; Superoxide Dismutase; Zinc	2006
[Study on the extraction of the active component in Atractylode macrocephala with ultrasonic wave technology optimized by the response surface method]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:7 Topics: Atractylodes; Lactones; Oils, Volatile; Particle Size; Plants, Medicinal; Polysaccharides; Rhizome; Sesquiterpenes; Technology, Pharmaceutical; Ultrasonics	2006
[Pharmacokinetics and tissue distribution of atractylenolide III in rats]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2006, Volume: 29, Issue:8 Topics: Animals; Area Under Curve; Atractylodes; Chromatography, High Pressure Liquid; Drug Stability; Drugs, Chinese Herbal; Female; Lactones; Lung; Male; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Spleen; Tissue Distribution	2006
[Process mechanism of Atractylodes macrocephala and conversion of sesquiterpenes]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:19 Topics: Atractylodes; Desiccation; Hot Temperature; Lactones; Molecular Structure; Oxidation-Reduction; Plants, Medicinal; Rhizome; Sesquiterpenes; Technology, Pharmaceutical; Temperature	2006
Atractylenolide I and atractylenolide III inhibit Lipopolysaccharide-induced TNF-alpha and NO production in macrophages. Phytotherapy research : PTR, 2007, Volume: 21, Issue:4 Topics: Animals; Atractylodes; Cell Survival; Lactones; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase Type II; Rhizome; RNA, Messenger; Sesquiterpenes; Tumor Necrosis Factor-alpha	2007
Determination of atractylenolide II in rat plasma by reversed-phase high-performance liquid chromatography. Biomedical chromatography : BMC, 2007, Volume: 21, Issue:3 Topics: Administration, Oral; Animals; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Lactones; Linear Models; Plasma; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Sesquiterpenes; Spectrophotometry, Ultraviolet	2007
Toxicity of atractylon and atractylenolide III Identified in Atractylodes ovata rhizome to Dermatophagoides farinae and Dermatophagoides pteronyssinus. Journal of agricultural and food chemistry, 2007, Jul-25, Volume: 55, Issue:15 Topics: Animals; Atractylodes; Dermatophagoides farinae; Dermatophagoides pteronyssinus; Fumigation; Insecticides; Lactones; Rhizome; Sesquiterpenes	2007
Anti-inflammatory components isolated from Atractylodes macrocephala Koidz. Natural product research, 2008, Volume: 22, Issue:16 Topics: Alkynes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atractylodes; Disease Models, Animal; Drugs, Chinese Herbal; Ear; Edema; Lactones; Mice; Molecular Structure; Plants, Medicinal; Sesquiterpenes; Xylenes	2008
[Simultaneous determination of atractylenolide III, atractylenolide I and atractylon in Artactylodis macrocephala using microbore liquid chromatography]. Se pu = Chinese journal of chromatography, 2008, Volume: 26, Issue:5 Topics: Atractylodes; Chromatography, Liquid; Lactones; Limit of Detection; Reproducibility of Results; Sesquiterpenes; Time Factors	2008
Sesquiterpene lactones from the root tubers of Lindera aggregata. Journal of natural products, 2009, Volume: 72, Issue:8 Topics: Antioxidants; Drugs, Chinese Herbal; Humans; Hydrogen Peroxide; Lactones; Lindera; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Sesquiterpenes	2009
Biotransformation of a herb plant metabolite by a cell disruptant of Chlamydomonas reinhardtii. Bioscience, biotechnology, and biochemistry, 2009, Volume: 73, Issue:12 Topics: Atractylodes; Biotransformation; Chlamydomonas reinhardtii; Dimethyl Sulfoxide; Lactones; Sesquiterpenes	2009
Gastroprotective activity of atractylenolide III from Atractylodes ovata on ethanol-induced gastric ulcer in vitro and in vivo. The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:3 Topics: Animals; Anti-Ulcer Agents; Atractylodes; Cell Membrane; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Discovery; Drugs, Chinese Herbal; Ethanol; Gastric Mucosa; Lactones; Male; Matrix Metalloproteinases, Secreted; Protein Isoforms; Rats; Rats, Wistar; Rhizome; Sesquiterpenes; Severity of Illness Index; Stomach Ulcer; Tissue Inhibitor of Metalloproteinases	2010
Atractylodes japonica Koidzumi inhibits the production of proinflammatory cytokines through inhibition of the NF-kappaB/IkappaB signal pathway in HMC-1 human mast cells. Archives of pharmacal research, 2010, Volume: 33, Issue:6 Topics: Animals; Anti-Inflammatory Agents; Atractylodes; Cell Line; Cell Survival; Cytokines; Gene Expression Regulation; Humans; I-kappa B Proteins; Lactones; Male; Mast Cells; Medicine, East Asian Traditional; NF-kappa B; Passive Cutaneous Anaphylaxis; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome; RNA, Messenger; Sesquiterpenes; Signal Transduction	2010
Atractylenolide III, a sesquiterpenoid, induces apoptosis in human lung carcinoma A549 cells via mitochondria-mediated death pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:2 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspase 3; Caspase 9; Cell Cycle; Cell Line, Tumor; Humans; Lactones; Lung Neoplasms; Mitochondria; Sesquiterpenes	2011
Blockade of IL-6 secretion pathway by the sesquiterpenoid atractylenolide III. Journal of natural products, 2011, Feb-25, Volume: 74, Issue:2 Topics: Caspase 1; Caspase Inhibitors; Histamine; Histamine Release; Humans; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lactones; Mast Cells; Molecular Structure; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Sesquiterpenes	2011
[Studies on the chemical constituents of Codonopsis pilosula]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2011, Volume: 34, Issue:4 Topics: Codonopsis; Hesperidin; Hydroxy Acids; Lactones; Molecular Structure; Oleic Acids; Plants, Medicinal; Polyynes; Quality Control; Sesquiterpenes	2011
[Study on processing technology and processing principles of atractrylodis macrocephalae rhizoma]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:8 Topics: Atractylodes; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lactones; Oils, Volatile; Rhizome; Sesquiterpenes; Technology, Pharmaceutical	2011
Simultaneous determination of atractylenolide II and atractylenolide III by liquid chromatography-tandem mass spectrometry in rat plasma and its application in a pharmacokinetic study after oral administration of Atractylodes Macrocephala Rhizoma extract. Biomedical chromatography : BMC, 2012, Volume: 26, Issue:11 Topics: Administration, Oral; Animals; Atractylodes; Chromatography, Liquid; Drug Stability; Lactones; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Sesquiterpenes; Tandem Mass Spectrometry	2012
Chemical and ecological evaluation of a genuine Chinese medicine: Atractylodes macrocephala Koidz. African journal of traditional, complementary, and alternative medicines : AJTCAM, 2011, Volume: 8, Issue:4 Topics: Atractylodes; Chromatography, High Pressure Liquid; Cluster Analysis; Ecology; Ecosystem; Humans; Lactones; Medicine, Chinese Traditional; Regression Analysis; Sesquiterpenes; Soil; Temperature	2011
Targeting of the Sonic Hedgehog pathway by atractylenolides promotes chondrogenic differentiation of mesenchymal stem cells. Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:8 Topics: Animals; Atractylodes; Biomarkers; Cell Differentiation; Chondrocytes; Hedgehog Proteins; Kruppel-Like Transcription Factors; Lactones; Mesenchymal Stem Cells; Plant Extracts; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Rhizome; Sesquiterpenes; Signal Transduction; Transcription, Genetic; Zinc Finger Protein GLI1	2012
The inhibitory activity of atractylenolide Ш, a sesquiterpenoid, on IgE-mediated mast cell activation and passive cutaneous anaphylaxis (PCA). Journal of ethnopharmacology, 2013, Jan-09, Volume: 145, Issue:1 Topics: Animals; Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Calcium; Cell Survival; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Gene Expression; Immunoglobulin E; Inhibitory Concentration 50; Intracellular Fluid; Lactones; Mast Cells; Mice; Passive Cutaneous Anaphylaxis; Phosphorylation; Rats; Sesquiterpenes; Signal Transduction	2013
Identification and quantification of atractylenolide I and atractylenolide III in Rhizoma Atractylodes Macrocephala by liquid chromatography-ion trap mass spectrometry. Biomedical chromatography : BMC, 2013, Volume: 27, Issue:6 Topics: Atractylodes; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lactones; Limit of Detection; Models, Molecular; Reproducibility of Results; Sesquiterpenes; Tandem Mass Spectrometry	2013
Content determination of the major constituents of Yinchenzhufu decoction via ultra high-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis, 2013, Apr-15, Volume: 77 Topics: Aconitine; Chlorogenic Acid; Chromatography, High Pressure Liquid; Cinnamates; Drugs, Chinese Herbal; Flavanones; Glycyrrhetinic Acid; Glycyrrhizic Acid; Lactones; Medicine, Chinese Traditional; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2013
[UFLC/Q-TOF-MS based analysis on material base of atractylodis macrocephalae rhizoma stir-fried with wheat bran]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:12 Topics: Atractylodes; Chromatography, Liquid; Dietary Fiber; Lactones; Mass Spectrometry; Principal Component Analysis; Sesquiterpenes	2013
Fast determination of two atractylenolides in Rhizoma Atractylodis Macrocephalae by Fourier transform near-infrared spectroscopy with partial least squares. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Volume: 120 Topics: Cholinergic Antagonists; Drugs, Chinese Herbal; Lactones; Least-Squares Analysis; Sensitivity and Specificity; Sesquiterpenes; Spectroscopy, Fourier Transform Infrared; Spectroscopy, Near-Infrared	2014
Metabolomic study of raw and processed Atractylodes macrocephala Koidz by LC-MS. Journal of pharmaceutical and biomedical analysis, 2014, Volume: 98 Topics: Atractylodes; Chromatography, High Pressure Liquid; Discriminant Analysis; Drugs, Chinese Herbal; Lactones; Mass Spectrometry; Medicine, Chinese Traditional; Metabolomics; Principal Component Analysis; Rhizome; Sesquiterpenes; Umbelliferones	2014
Neuroprotection of atractylenolide III from Atractylodis macrocephalae against glutamate-induced neuronal apoptosis via inhibiting caspase signaling pathway. Neurochemical research, 2014, Volume: 39, Issue:9 Topics: Animals; Apoptosis; Asteraceae; Caspase 3; Glutamic Acid; Lactones; Male; Mice, Inbred BALB C; Neurons; Neuroprotective Agents; Sesquiterpenes; Signal Transduction	2014
Neuroprotection and mechanisms of atractylenolide III in preventing learning and memory impairment induced by chronic high-dose homocysteine administration in rats. Neuroscience, 2015, Apr-02, Volume: 290 Topics: Animals; Apoptosis; Caspase 3; Cells, Cultured; Hippocampus; Homocysteine; Lactones; Learning Disabilities; Male; Maze Learning; Memory Disorders; Neurons; Neuroprotective Agents; Protein Kinase C; Random Allocation; Rats, Wistar; Reactive Oxygen Species; Sesquiterpenes; Spatial Memory	2015
Simultaneous determination and pharmacokinetic study of Atractylenolide I, II and III in rat plasma after intragastric administration of Baizhufuling extract and Atractylodis extract by UPLC-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015, Jul-01, Volume: 993-994 Topics: Animals; Atractylodes; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lactones; Limit of Detection; Male; Poria; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tandem Mass Spectrometry	2015
The natural compound codonolactone impairs tumor induced angiogenesis by downregulating BMP signaling in endothelial cells. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2015, Oct-15, Volume: 22, Issue:11 Topics: Angiogenesis Inhibitors; Animals; Aorta; Atractylodes; Bone Morphogenetic Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Core Binding Factor Alpha 1 Subunit; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Lactones; Male; Matrix Metalloproteinases; Neovascularization, Pathologic; Rats, Sprague-Dawley; Sesquiterpenes; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2	2015
Strong Specific Inhibition of UDP-glucuronosyltransferase 2B7 by Atractylenolide I and III. Phytotherapy research : PTR, 2016, Volume: 30, Issue:1 Topics: Drug Interactions; Glucuronosyltransferase; Humans; Hymecromone; Kinetics; Lactones; Protein Isoforms; Recombinant Proteins; Sesquiterpenes	2016
The natural compound codonolactone attenuates TGF-β1-mediated epithelial-to-mesenchymal transition and motility of breast cancer cells. Oncology reports, 2016, Volume: 35, Issue:1 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Lactones; Mice; Neoplasm Metastasis; Sesquiterpenes; Signal Transduction; Transforming Growth Factor beta1; Xenograft Model Antitumor Assays	2016
Anti-inflammatory activity of atractylenolide III through inhibition of nuclear factor-κB and mitogen-activated protein kinase pathways in mouse macrophages. Immunopharmacology and immunotoxicology, 2016, Volume: 38, Issue:2 Topics: Animals; Cell Line; Cyclooxygenase 2; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Interleukin-6; Lactones; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mice; NF-kappa B; Nitric Oxide; Sesquiterpenes; Signal Transduction; Transcription, Genetic; Tumor Necrosis Factor-alpha	2016
Classification of the medicinal plants of the genus Atractylodes using high-performance liquid chromatography with diode array and tandem mass spectrometry detection combined with multivariate statistical analysis. Journal of separation science, 2016, Volume: 39, Issue:7 Topics: Atractylodes; Chromatography, High Pressure Liquid; Furans; Lactones; Multivariate Analysis; Plants, Medicinal; Rhizome; Sesquiterpenes; Tandem Mass Spectrometry	2016
[An exploration in the action targets for antidepressant bioactive components of Xiaoyaosan based on network pharmacology]. Yao xue xue bao = Acta pharmaceutica Sinica, 2015, Volume: 50, Issue:12 Topics: Antidepressive Agents; Benzoates; Bridged-Ring Compounds; Coumaric Acids; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Flavanones; Glucosides; Glycyrrhizic Acid; Lactones; Medicine, Chinese Traditional; Monoterpenes; Sesquiterpenes; Software	2015
Two new compounds from Atractylodes macrocephala with neuroprotective activity. Journal of Asian natural products research, 2017, Volume: 19, Issue:1 Topics: Atractylodes; Drugs, Chinese Herbal; Humans; Lactones; Molecular Structure; Neuroprotective Agents; Nuclear Magnetic Resonance, Biomolecular; Rhizome; Sesquiterpenes	2017
Atractylenolide III Enhances Energy Metabolism by Increasing the SIRT-1 and PGC1α Expression with AMPK Phosphorylation in C2C12 Mouse Skeletal Muscle Cells. Biological & pharmaceutical bulletin, 2017, Volume: 40, Issue:3 Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Atractylodes; Blood Glucose; Cell Line; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Energy Metabolism; High Mobility Group Proteins; Lactones; Mice; Mitochondria; Muscle Fibers, Skeletal; Muscle, Skeletal; Nuclear Respiratory Factor 1; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Plant Extracts; Sesquiterpenes; Sirtuin 1	2017
Ameliorative effect of atractylenolide III in the mast cell proliferation induced by TSLP. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 106, Issue:Pt A Topics: Anti-Inflammatory Agents; Atractylodes; Caspase 3; Cell Line; Cell Proliferation; Cytokines; Humans; Interleukin-13; Lactones; Mast Cells; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-mdm2; Sesquiterpenes; STAT6 Transcription Factor; Thymic Stromal Lymphopoietin	2017
[Study on TLC identification and UPLC determination method of atractylenolide in Atractylodes macrocephala]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:3 Topics: Atractylodes; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Lactones; Quality Control; Sensitivity and Specificity; Sesquiterpenes	2017
A High Throughput Three-step Ultra-performance Liquid Chromatography Tandem Mass Spectrometry Method to Study Metabolites of Atractylenolide-III. Journal of chromatographic science, 2019, Feb-01, Volume: 57, Issue:2 Topics: Animals; Chromatography, High Pressure Liquid; Feces; Lactones; Male; Metabolic Networks and Pathways; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tandem Mass Spectrometry	2019
UPLC-MS/MS of Atractylenolide I, Atractylenolide II, Atractylenolide III, and Atractyloside A in Rat Plasma after Oral Administration of Raw and Wheat Bran-Processed Atractylodis Rhizoma. Molecules (Basel, Switzerland), 2018, Dec-07, Volume: 23, Issue:12 Topics: Administration, Oral; Animals; Area Under Curve; Atractylodes; Atractyloside; Chromatography, High Pressure Liquid; Dietary Fiber; Lactones; Limit of Detection; Linear Models; Rats, Sprague-Dawley; Reproducibility of Results; Rhizome; Sesquiterpenes; Tandem Mass Spectrometry	2018
Response of Bioactive Metabolite and Biosynthesis Related Genes to Methyl Jasmonate Elicitation in Molecules (Basel, Switzerland), 2019, Feb-01, Volume: 24, Issue:3 Topics: Acetates; Biomass; Codonopsis; Cyclopentanes; Fatty Acids; Gene Expression Regulation, Plant; Lactones; Metabolic Networks and Pathways; Oxylipins; Phosphotransferases (Phosphate Group Acceptor); Plant Growth Regulators; Plant Proteins; Plant Roots; Plant Shoots; Polyynes; Sesquiterpenes; UTP-Glucose-1-Phosphate Uridylyltransferase	2019
Atractylenolide III ameliorates cerebral ischemic injury and neuroinflammation associated with inhibiting JAK2/STAT3/Drp1-dependent mitochondrial fission in microglia. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 59 Topics: Animals; Brain Ischemia; Cytokines; Dynamins; Gene Expression Regulation; Glucose; Inflammation; Interleukin-1beta; Janus Kinase 2; Lactones; Male; Mice; Microglia; Mitochondrial Dynamics; Phosphorylation; Sesquiterpenes; Signal Transduction; STAT3 Transcription Factor; Stroke	2019
In vivo metabolic profiles of Bu-Zhong-Yi-Qi-Tang, a famous traditional Chinese medicine prescription, in rats by ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis, 2019, Jul-15, Volume: 171 Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Feces; Flavonoids; Lactones; Male; Metabolic Detoxication, Phase I; Metabolic Detoxication, Phase II; Metabolome; Molecular Structure; Rats, Sprague-Dawley; Sesquiterpenes; Tandem Mass Spectrometry; Triterpenes	2019
Involvement of mitochondrial apoptotic pathway and MAPKs/NF-κ B inflammatory pathway in the neuroprotective effect of atractylenolide III in corticosterone-induced PC12 cells. Chinese journal of natural medicines, 2019, Volume: 17, Issue:4 Topics: Animals; Apoptosis; Calcium; Cell Survival; Corticosterone; Inflammation Mediators; L-Lactate Dehydrogenase; Lactones; Mitochondria; Mitogen-Activated Protein Kinases; Neuroprotective Agents; NF-kappa B; PC12 Cells; Phosphorylation; Rats; Sesquiterpenes; Signal Transduction	2019
Atractylenolide III Attenuates Muscle Wasting in Chronic Kidney Disease via the Oxidative Stress-Mediated PI3K/AKT/mTOR Pathway. Oxidative medicine and cellular longevity, 2019, Volume: 2019 Topics: Animals; Cholinergic Antagonists; Humans; Lactones; Male; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Sesquiterpenes; TOR Serine-Threonine Kinases	2019
Atractylodis Rhizoma Alba Attenuates Neuroinflammation in BV2 Microglia upon LPS Stimulation by Inducing HO-1 Activity and Inhibiting NF-κB and MAPK. International journal of molecular sciences, 2019, Aug-17, Volume: 20, Issue:16 Topics: Animals; Asteraceae; Cell Line; Cyclooxygenase 2; Cytokines; Gene Expression Regulation; Heme Oxygenase-1; Inflammation; Lactones; Lipopolysaccharides; Mice; Microglia; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Plant Preparations; Plant Roots; Sesquiterpenes; Signal Transduction	2019
Atractylenolide III Enhances the Anti-Neoplastic Efficacy of Docetaxel in Gastric Cancer Cell by Inhibiting Fibroblast Growth Factor Receptors 1, -2, and -4 Expression. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2019, Volume: 38, Issue:3 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Docetaxel; Gene Expression; Humans; Lactones; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 4; Sesquiterpenes; Stomach Neoplasms	2019
Inhibition of cholesteryl ester synthesis by polyacetylenes from Atractylodes rhizome. Bioorganic & medicinal chemistry letters, 2020, 04-01, Volume: 30, Issue:7 Topics: Animals; Atractylodes; CHO Cells; Cholesterol Esters; Cricetulus; Enzyme Assays; Enzyme Inhibitors; Lactones; Microsomes; Polyynes; Rhizome; Sesquiterpenes; Sterol O-Acyltransferase	2020
Atractylenolide III reduces NLRP3 inflammasome activation and Th1/Th2 imbalances in both in vitro and in vivo models of asthma. Clinical and experimental pharmacology & physiology, 2020, Volume: 47, Issue:8 Topics: Animals; Asthenia; Cell Line; Disease Models, Animal; Humans; Inflammasomes; Lactones; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Sesquiterpenes; Th1 Cells; Th2 Cells	2020
Atractylenolide III attenuates bleomycin-induced experimental pulmonary fibrosis and oxidative stress in rat model via Nrf2/NQO1/HO-1 pathway activation. Immunopharmacology and immunotoxicology, 2020, Volume: 42, Issue:5 Topics: Animals; Antioxidants; Apoptosis; Bleomycin; Disease Models, Animal; Heme Oxygenase (Decyclizing); Lactones; Lung; Male; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Pulmonary Fibrosis; Rats, Sprague-Dawley; Sesquiterpenes; Signal Transduction	2020
Atractylenolide III alleviates the apoptosis through inhibition of autophagy by the mTOR-dependent pathway in alveolar macrophages of human silicosis. Molecular and cellular biochemistry, 2021, Volume: 476, Issue:2 Topics: Apoptosis; Autophagy; Bronchoalveolar Lavage Fluid; Cells, Cultured; Cholinergic Antagonists; Humans; Lactones; Macrophages, Alveolar; Sesquiterpenes; Silicosis; TOR Serine-Threonine Kinases	2021
Atractylenolide III predisposes miR-195-5p/FGFR1 signaling axis to exert tumor-suppressive functions in liver cancer. Journal of food biochemistry, 2021, Volume: 45, Issue:5 Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Lactones; Liver Neoplasms; MicroRNAs; Receptor, Fibroblast Growth Factor, Type 1; Sesquiterpenes	2021
Protective effects of Atractylenolide III on inflammation and oxidative stress in ovalbumin-induced asthma mice and its possible mechanisms. General physiology and biophysics, 2021, Volume: 40, Issue:2 Topics: Animals; Asthma; Cytokines; Disease Models, Animal; Inflammation; Lactones; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Oxidative Stress; Sesquiterpenes	2021
Atractylenolide III reduces depressive- and anxiogenic-like behaviors in rat depression models. Neuroscience letters, 2021, 08-10, Volume: 759 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Cytokines; Depression; Disease Models, Animal; Hippocampus; Lactones; Male; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Stress, Psychological	2021
Atractylenolide III Ameliorates TNBS-Induced Intestinal Inflammation in Mice by Reducing Oxidative Stress and Regulating Intestinal Flora. Chemistry & biodiversity, 2021, Volume: 18, Issue:8 Topics: Animals; Anti-Inflammatory Agents; Colitis; Disease Models, Animal; Down-Regulation; Gastrointestinal Microbiome; Interleukin-1beta; Lactones; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Sesquiterpenes; Signal Transduction; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Up-Regulation	2021
Atractylenolide III induces apoptosis by regulating the Bax/Bcl-2 signaling pathway in human colorectal cancer HCT-116 Cells in vitro and in vivo. Anti-cancer drugs, 2022, 01-01, Volume: 33, Issue:1 Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; Humans; Lactones; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Proto-Oncogene Proteins c-bcl-2; Rats; Sesquiterpenes; Signal Transduction; Xenograft Model Antitumor Assays	2022
Atractylenolide III alleviates isoflurane-induced injury in rat hippocampal neurons by activating the PI3K/Akt/mTOR pathway. Journal of food biochemistry, 2021, Volume: 45, Issue:9 Topics: Animals; Hippocampus; Humans; Isoflurane; Lactones; Neurons; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Sesquiterpenes; TOR Serine-Threonine Kinases	2021
Atractylenolide III alleviates sepsis-mediated lung injury via inhibition of FoxO1 and VNN1 protein. Acta cirurgica brasileira, 2021, Volume: 36, Issue:8 Topics: Amidohydrolases; Animals; Apoptosis; Forkhead Box Protein O1; GPI-Linked Proteins; Lactones; Lung Injury; Mice; Sepsis; Sesquiterpenes	2021
Atractylenolide III inhibits epithelial‑mesenchymal transition in small intestine epithelial cells by activating the AMPK signaling pathway. Molecular medicine reports, 2022, Volume: 25, Issue:3 Topics: AMP-Activated Protein Kinases; Animals; Cell Line, Tumor; Cell Movement; Epithelial Cells; Epithelial-Mesenchymal Transition; Intestine, Small; Lactones; Rats; Sesquiterpenes; Signal Transduction	2022
Anti-apoptosis effects of codonolactone on cerebral ischemia-reperfusion injury. Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2022, Volume: 70, Issue:5 Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Brain Ischemia; Humans; Lactones; NF-E2-Related Factor 2; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sesquiterpenes; Superoxide Dismutase; Tumor Necrosis Factor-alpha	2022
Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization. CNS neuroscience & therapeutics, 2022, Volume: 28, Issue:7 Topics: Animals; Anti-Inflammatory Agents; Lactones; Macrophages; Microglia; Rats; Sesquiterpenes; Spinal Cord; Spinal Cord Injuries	2022
Atractylenolide III from Atractylodes macrocephala Koidz promotes the activation of brown and white adipose tissue through SIRT1/PGC-1α signaling pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 104 Topics: Adipose Tissue, White; Animals; Atractylodes; Lactones; Mice; Mice, Inbred C57BL; Sesquiterpenes; Signal Transduction; Sirtuin 1; Transcription Factors	2022
[Mechanism of atractylenolide Ⅲ in alleviating H9c2 cell apoptosis through ROS/GRP78/caspase-12 signaling pathway based on molecular docking]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:16 Topics: Apoptosis; Calcium; Caspase 12; Caspase 3; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Lactones; Molecular Docking Simulation; Reactive Oxygen Species; RNA, Messenger; Sesquiterpenes; Signal Transduction; Superoxide Dismutase	2022