Compounds > atovaquone

Page last updated: 2024-08-25

atovaquone and ubiquinone

atovaquone has been researched along with ubiquinone in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (7.14)	18.2507
2000's	9 (64.29)	29.6817
2010's	2 (14.29)	24.3611
2020's	2 (14.29)	2.80

Authors

Authors	Studies
Daldal, F; Darrouzet, E; Morrisey, JM; Srivastava, IK; Vaidya, AB	1
Hazra, B; Kaneshiro, ES; Sul, D	1
Berry, EA; Boothroyd, JC; McFadden, DC; Tomavo, S	1
Armstrong, W; Beard, CB; Burman, W; Carter, J; Crane, L; Duchin, J; Hossler, PA; Huang, L; Kazanjian, P; Lee, CH; Meshnick, SR; Richardson, J	1
Basselin, M; Kaneshiro, ES; Kayser, O; Sul, D	1
Chen, N; Cheng, Q; Fowler, EV; Gatton, M; Korsinczky, M; Manzetti, S; Peters, JM; Saul, A	1
Hill, P; Hunte, C; Kessl, JJ; Lange, BB; Merbitz-Zahradnik, T; Meshnick, S; Meunier, B; Pálsdóttir, H; Trumpower, BL; Zwicker, K	1
Ha, KH; Hill, P; Kessl, JJ; Lange, BB; Merritt, AK; Meshnick, SR; Meunier, B; Trumpower, BL	1
Abdala-Valencia, H; Basselin, M; Hunt, SM; Kaneshiro, ES	1
Mather, MW; Morrisey, JM; Painter, HJ; Vaidya, AB	1
Ganesan, SM; Ke, H; Mather, MW; Morrisey, JM; Painter, HJ; Vaidya, AB	1
Bergman, LW; Daly, TM; Jenkins, BJ; Mather, MW; Morrisey, JM; Vaidya, AB	1
Meunier, B; Michel, T; Mounkoro, P	1
Almeida, FG; Azevedo, MF; Buriticá, NL; Crispim, M; Katzin, AM; Kimura, EA; Melo, HR; Sussmann, RAC; Verdaguer, IB; Zafra, CA	1

Other Studies

14 other study(ies) available for atovaquone and ubiquinone

Article	Year
Resistance mutations reveal the atovaquone-binding domain of cytochrome b in malaria parasites. Molecular microbiology, 1999, Volume: 33, Issue:4 Topics: Amino Acid Sequence; Animals; Antimalarials; Atovaquone; Base Sequence; Chickens; Cytochrome b Group; DNA, Mitochondrial; Drug Resistance; Electron Transport; Membrane Potentials; Methacrylates; Mice; Mice, Inbred BALB C; Mitochondria; Models, Molecular; Molecular Sequence Data; Naphthoquinones; Plasmodium yoelii; Sequence Analysis, DNA; Thiazoles; Ubiquinone	1999
Effects of atovaquone and diospyrin-based drugs on ubiquinone biosynthesis in Pneumocystis carinii organisms. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:1 Topics: Antifungal Agents; Atovaquone; Dose-Response Relationship, Drug; Naphthoquinones; Oxygen Consumption; Parabens; Pneumocystis; Ubiquinone	2000
Characterization of cytochrome b from Toxoplasma gondii and Q(o) domain mutations as a mechanism of atovaquone-resistance. Molecular and biochemical parasitology, 2000, Apr-30, Volume: 108, Issue:1 Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Atovaquone; Binding Sites; Blotting, Northern; Cytochrome b Group; Drug Resistance; Drug Resistance, Multiple; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Naphthoquinones; Protein Conformation; Protozoan Proteins; Reverse Transcriptase Polymerase Chain Reaction; Toxoplasma; Ubiquinone	2000
Pneumocystis carinii cytochrome b mutations are associated with atovaquone exposure in patients with AIDS. The Journal of infectious diseases, 2001, Mar-01, Volume: 183, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Adult; Antifungal Agents; Atovaquone; Case-Control Studies; Cohort Studies; Cytochrome b Group; Female; Gene Amplification; Humans; Male; Middle Aged; Molecular Sequence Data; Naphthoquinones; Pneumocystis; Pneumonia, Pneumocystis; Polymerase Chain Reaction; Polymorphism, Genetic; Retrospective Studies; Survival; Treatment Outcome; Ubiquinone	2001
Pneumocystis carinii synthesizes four ubiquinone homologs: inhibition by atovaquone and bupravaquone but not by stigmatellin. The Journal of eukaryotic microbiology, 2001, Volume: Suppl Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Atovaquone; Female; Naphthoquinones; Oxidoreductases; Parabens; Pneumocystis; Polyenes; Rats; Ubiquinone	2001
Mutations in cytochrome b resulting in atovaquone resistance are associated with loss of fitness in Plasmodium falciparum. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:8 Topics: Amino Acid Substitution; Animals; Antimalarials; Atovaquone; Binding Sites; Chromosome Mapping; Cytochrome b Group; DNA Fingerprinting; DNA, Protozoan; Drug Resistance; Models, Molecular; Mutation; Naphthoquinones; Plasmodium falciparum; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Ubiquinone	2002
Molecular basis for atovaquone binding to the cytochrome bc1 complex. The Journal of biological chemistry, 2003, Aug-15, Volume: 278, Issue:33 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Atovaquone; Binding Sites; Binding, Competitive; Electron Transport Complex III; Molecular Sequence Data; Naphthoquinones; Oxidation-Reduction; Polyenes; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharomyces cerevisiae; Ubiquinone	2003
Cytochrome b mutations that modify the ubiquinol-binding pocket of the cytochrome bc1 complex and confer anti-malarial drug resistance in Saccharomyces cerevisiae. The Journal of biological chemistry, 2005, Apr-29, Volume: 280, Issue:17 Topics: Amino Acid Sequence; Animals; Antimalarials; Atovaquone; Cytochromes b; Dose-Response Relationship, Drug; Electron Transport Complex III; Inhibitory Concentration 50; Kinetics; Malaria; Models, Molecular; Molecular Sequence Data; Mutation; Naphthoquinones; Oxygen Consumption; Plasmodium falciparum; Point Mutation; Protein Binding; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Time Factors; Ubiquinone	2005
Ubiquinone synthesis in mitochondrial and microsomal subcellular fractions of Pneumocystis spp.: differential sensitivities to atovaquone. Eukaryotic cell, 2005, Volume: 4, Issue:8 Topics: Animals; Antimycin A; Atovaquone; Benzphetamine; Coenzymes; Dicyclohexylcarbodiimide; Dose-Response Relationship, Drug; Drug Resistance, Fungal; Female; Hydrogen-Ion Concentration; Kinetics; Microscopy, Fluorescence; Microsomes; Mitochondria; Naphthoquinones; Pneumocystis; Rats; Sensitivity and Specificity; Subcellular Fractions; Temperature; Time Factors; Ubiquinone	2005
Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum. Nature, 2007, Mar-01, Volume: 446, Issue:7131 Topics: Animals; Animals, Genetically Modified; Atovaquone; Dihydroorotate Dehydrogenase; Electron Transport; Membrane Potential, Mitochondrial; Mitochondria; Oxidoreductases Acting on CH-CH Group Donors; Plasmodium falciparum; Proguanil; Saccharomyces cerevisiae; Ubiquinone	2007
Variation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain function. Eukaryotic cell, 2011, Volume: 10, Issue:8 Topics: Antimalarials; Atovaquone; Cells, Cultured; Dihydroorotate Dehydrogenase; Drug Resistance; Electron Transport; Fungal Proteins; Humans; Mitochondria; Organisms, Genetically Modified; Oxidoreductases Acting on CH-CH Group Donors; Parasitemia; Plasmodium falciparum; Recombinant Proteins; Ubiquinone	2011
Characterization of a Plasmodium falciparum Orthologue of the Yeast Ubiquinone-Binding Protein, Coq10p. PloS one, 2016, Volume: 11, Issue:3 Topics: Atovaquone; Carrier Proteins; Gene Expression Regulation; Humans; Malaria, Falciparum; Mitochondria; Plasmodium falciparum; Respiration; Saccharomyces cerevisiae; Ubiquinone	2016
Revisiting the mode of action of the antimalarial proguanil using the yeast model. Biochemical and biophysical research communications, 2021, 01-01, Volume: 534 Topics: Antimalarials; Atovaquone; Drug Resistance, Fungal; Drug Synergism; Drug Therapy, Combination; Membrane Potential, Mitochondrial; Mutation; Oxygen; Proguanil; Pyrimidines; Strobilurins; Ubiquinone; Vitamin K 3; Yeasts	2021
Exploring Ubiquinone Biosynthesis Inhibition as a Strategy for Improving Atovaquone Efficacy in Malaria. Antimicrobial agents and chemotherapy, 2021, 03-18, Volume: 65, Issue:4 Topics: Atovaquone; Humans; Malaria; Mitochondria; Oxidation-Reduction; Ubiquinone	2021