atorvastatin has been researched along with ubiquinone in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 18 (33.96) | 29.6817 |
| 2010's | 30 (56.60) | 24.3611 |
| 2020's | 5 (9.43) | 2.80 |
| Authors | Studies |
|---|---|
| Anthony, M; Bleske, BE; Casselberry, N; Datwani, M; Secontine, SG; Shea, MJ; Uhley, VE; Willis, RA | 1 |
| Lemmens, PJ; Oranje, WA; Rondas-Colbers, GJ; Sels, JP; Wolffenbuttel, BH | 1 |
| Aleo, E; Dmitrieva, A; Littarru, GP; Passi, S; Stancato, A | 1 |
| Langsjoen, PH; Patil, H; Silver, MA; Szabo, S; Zelinger, A | 2 |
| Coates, K; DiMauro, S; Naini, A; Rundek, T; Sacco, R | 1 |
| Neale, R; Reynolds, TM; Saweirs, W | 1 |
| Cartwright, MS; Donofrio, PD; Jeffery, DR; Nuss, GR | 1 |
| Florkowski, CM; Frampton, CM; George, PM; Molyneux, SL; Scott, RS; Strey, CH; Young, JM | 1 |
| Higashikata, T; Inazu, A; Katsuda, S; Kawashiri, M; Kobayashi, J; Koizumi, J; Mabuchi, H; Mizuno, M; Nohara, A | 1 |
| De Paepe, B; Laakso, J; Laaksonen, R; Lehtimäki, T; Lütjohann, D; Mattila, KM; Päivä, H; Smet, J; Thelen, KM; Van Coster, R; von Bergmann, K | 1 |
| Mongini, T; Musumeci, O; Olivero, N; Palmucci, L; Rodolico, C; Vercelli, L | 1 |
| Bestari, K; Brain, RA; Lissemore, LI; Reitsma, TS; Sibley, PK; Solomon, KR | 1 |
| Côté, HC; Frohlich, JJ; Humphries, KH; Laaksonen, R; Lehtimäki, T; Päivä, H; Schick, BA | 1 |
| Chen, SH; Chu, CS; Kou, HS; Lai, WT; Lee, CJ; Lee, KT; Sheu, SH; Voon, WC | 1 |
| Inazu, A; Katsuda, S; Kawashiri, MA; Kobayashi, J; Koizumi, J; Mabuchi, H; Nohara, A | 1 |
| Inazu, A; Katsuda, S; Kawashiri, MA; Kobayashi, J; Koizumi, J; Mabuchi, H; Mori, M; Nohara, A; Tada, H; Tsuchida, M; Yamagishi, M | 1 |
| Fujii, N; Igarashi, N; Inoue, H; Matsuki, A; Nozawa, T; Sobajima, M; Suzuki, T | 1 |
| Chang, LL; Chen, HW; Cheng, WL; Kuo, CL; Lii, CK; Liu, CS; Su, SL; Tsai, CW | 1 |
| Atanasova, P; Bełtowski, J; Chaldakov, GN; Chylińska-Kula, B; Jamroz-Wiśniewska, A; Wójcicka, G | 1 |
| Djalali, M; Eshraghian, M; Khatami, M; Shojaei, M; Siassi, F | 1 |
| Iwasaki, Y; Jinnouchi, H; Matsui, K; Ogawa, H; Oka, H; Sugiyama, S; Sumida, H; Tanaka, T; Tayama, S; Toyama, K | 1 |
| Andalib, S; Biabani, S; Doustar, Y; Garjani, A; Maleki-Dizaji, N; Soraya, H | 1 |
| Barone, E; Butterfield, DA; Cenini, G; Dowling, AL; Head, E; Mancuso, C; Martin, SB; Murphy, MP | 1 |
| Bada, V; Bozek, P; Gvozdjakova, A; Kucharska, J; Ulicna, O; Vancova, O; Waczulikova, I | 1 |
| Bada, V; Božek, P; Kucharská, J; Šikurová, L; Uličná, O; Vančová, O; Waczulíková, I | 1 |
| Itoh, H; Mitsuishi, M; Miyashita, K; Muraki, A; Tamaki, M; Tanaka, K | 1 |
| Gong, FY; Lu, YS; Qu, RB | 1 |
| Arnesen, KE; Bogsrud, MP; Langslet, G; Malt, UF; Ose, L; Retterstøl, K; Sm Stuen, MC; Woldseth, B | 1 |
| García-Estévez, DA; Navarro, C; San Millán, B; Sogo, T | 1 |
| Groenemeijer, M; Nanayakkara, PW; Scheffer, PG; Schindhelm, RK; Simsek, S; Smulders, YM; van Verschuer, VM | 1 |
| Andalib, S; Garjani, A; Khorrami, A; Maleki-Dijazi, N; Shayanfar, A | 1 |
| Bermúdez-Ocaña, DY; Díaz-Zagoya, JC; Espinosa-García, MT; Jiménez-Santos, MA; Juárez-Oropeza, MA; Juárez-Rojop, IE; Ramón-Frías, T; Tovilla-Zárate, CA | 1 |
| Abdoli, N; Azarmi, Y; Eghbal, MA | 1 |
| Abdelbaset, M; Agha, AM; Mahmoud, SS; Negm, SA; Safar, MM | 1 |
| Chitose, T; Hokamaki, J; Ogawa, H; Sakamoto, K; Shimomura, H; Shiraishi, S; Sugiyama, S; Tsunoda, R; Yamashita, T; Yamashita, Y | 1 |
| Hunter, ML; Mahvan, TD; Mlodinow, SG; Onysko, MK; Vandiver, JW | 1 |
| Abdulghani, HM; Al-Drees, A; Khalil, MS; Khamis, N | 1 |
| Nater, H; Perger, L; Suter, PM | 1 |
| Murad, HA | 1 |
| Abdallah, D; El-Ganainy, SO; El-Khatib, AS; El-Mallah, A; Khattab, MM; Mohy El-Din, MM | 2 |
| Garabadu, D; Krishnamurthy, S; Prajapati, SK | 1 |
| Moon, TW; Pasha, R | 1 |
| Murphy, G; Murphy, JEJ; O'Gorman, SM; Powers, JM; Ralph, N | 1 |
| Faizi, M; Khodagholi, F; Naderi, N; Nasoohi, S; Nikseresht, S; Simani, L | 1 |
| El-Yamany, MF; Farrag, SM; Hamzawy, MA; Nassar, NN; Saad, MA | 1 |
| Andersen, LW; Chase, M; Cocchi, MN; Donnino, MW; Holmberg, MJ; Liu, X | 1 |
| Salami, M; Soheili, M | 1 |
| Kondratenko, S; Kukes, V; Melnikov, E; Shikh, E; Zozina, V | 1 |
| Gupta, LK; Gurha, N; Rehan, HS; Yadav, M | 1 |
| Christiansen, LB; Ciborowski, M; Desler, C; Dohlmann, TL; Kretowski, A; Larsen, S; Ludvigsen, TP; Martinussen, T; Olsen, LH; Orlando, P; Parfieniuk, E; Szczerbinski, L; Tiano, L | 1 |
| Alshogran, OY; Alzoubi, KH; El-Elimat, T; Nusair, SD; Obeidat, A; Sweidan, M | 1 |
2 review(s) available for atorvastatin and ubiquinone
| Article | Year |
|---|---|
Statin precipitated lactic acidosis?
Topics: Acidosis, Lactic; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Diet; Female; Heptanoic Acids; Humans; Pyrroles; Thiamine Deficiency; Ubiquinone | 2004 |
[Help me--I do not tolerate my statin].
Topics: Aged; Aged, 80 and over; Atorvastatin; Diagnosis, Differential; Drug Substitution; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Myalgia; Patient Education as Topic; Pyrroles; Quinolines; Risk Factors; Ubiquinone | 2015 |
16 trial(s) available for atorvastatin and ubiquinone
| Article | Year |
|---|---|
The effect of pravastatin and atorvastatin on coenzyme Q10.
Topics: Adult; Atorvastatin; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Chromatography, High Pressure Liquid; Coenzymes; Coronary Disease; Cross-Over Studies; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Pravastatin; Pyrroles; Reference Values; Triglycerides; Ubiquinone | 2001 |
Effect of atorvastatin on LDL oxidation and antioxidants in normocholesterolemic type 2 diabetic patients.
Topics: Aged; Anticholesteremic Agents; Antioxidants; Atorvastatin; Blood Glucose; Cholesterol, LDL; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glycated Hemoglobin; Heptanoic Acids; Humans; Lipids; Male; Middle Aged; Oxidation-Reduction; Pyrroles; Ubiquinone; Vitamin E | 2001 |
Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction.
Topics: Aged; Anticholesteremic Agents; Antioxidants; Atorvastatin; Coenzymes; Echocardiography, Doppler; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pyrroles; Ubiquinone; Ventricular Function, Left | 2004 |
Endothelium-ameliorating effects of statin therapy and coenzyme Q10 reductions in chronic heart failure.
Topics: Atorvastatin; Chronic Disease; Coenzymes; Cross-Over Studies; Endothelium, Vascular; Heart Failure; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Ubiquinone; Vascular Resistance; Vasodilation | 2005 |
Reduction of serum ubiquinol-10 and ubiquinone-10 levels by atorvastatin in hypercholesterolemic patients.
Topics: Aged; Atorvastatin; Biomarkers; Cholesterol; Coenzymes; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Pyrroles; Risk Factors; Treatment Outcome; Ubiquinone | 2005 |
High-dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial.
Topics: Adult; Age Factors; Aged; Atorvastatin; Biopsy; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Citrate (si)-Synthase; Dose-Response Relationship, Drug; Double-Blind Method; Electron Transport; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Muscles; Patient Selection; Phytosterols; Pyrroles; Sex Factors; Simvastatin; Sitosterols; Succinate Cytochrome c Oxidoreductase; Time Factors; Ubiquinone | 2005 |
Decreased skeletal muscle mitochondrial DNA in patients treated with high-dose simvastatin.
Topics: Adult; Aged; Atorvastatin; DNA, Mitochondrial; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Longitudinal Studies; Male; Middle Aged; Mitochondria, Muscle; Pyrroles; Retrospective Studies; Simvastatin; Ubiquinone | 2007 |
Effects of CoQ10 supplementation on plasma lipoprotein lipid, CoQ10 and liver and muscle enzyme levels in hypercholesterolemic patients treated with atorvastatin: a randomized double-blind study.
Topics: Aged; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Coenzymes; Double-Blind Method; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver Function Tests; Male; Middle Aged; Muscles; Myoglobin; Pyrroles; Ubiquinone; Vitamins | 2007 |
Comparison of effects of pitavastatin and atorvastatin on plasma coenzyme Q10 in heterozygous familial hypercholesterolemia: results from a crossover study.
Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol; Cholesterol, LDL; Coenzymes; Cross-Over Studies; Female; Heptanoic Acids; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Pyrroles; Quinolines; Triglycerides; Ubiquinone | 2008 |
Atorvastatin increases blood ratios of vitamin E/low-density lipoprotein cholesterol and coenzyme Q10/low-density lipoprotein cholesterol in hypercholesterolemic patients.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Deoxyguanosine; Erythrocytes; Female; Glutathione; Heptanoic Acids; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Oxidative Stress; Pyrroles; Ubiquinone; Vitamin E | 2010 |
Effects of carnitine and coenzyme Q10 on lipid profile and serum levels of lipoprotein(a) in maintenance hemodialysis patients on statin therapy.
Topics: Adult; Aged; Aged, 80 and over; Atorvastatin; Carnitine; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Lipoprotein(a); Lovastatin; Male; Middle Aged; Pyrroles; Renal Dialysis; Ubiquinone; Young Adult | 2011 |
Rosuvastatin combined with regular exercise preserves coenzyme Q10 levels associated with a significant increase in high-density lipoprotein cholesterol in patients with coronary artery disease.
Topics: Aged; Atorvastatin; Cholesterol, HDL; Coronary Artery Disease; Echocardiography; Exercise; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Multivariate Analysis; Pyrimidines; Pyrroles; Risk; Rosuvastatin Calcium; Smoking; Sulfonamides; Ubiquinone | 2011 |
No effect of combined coenzyme Q10 and selenium supplementation on atorvastatin-induced myopathy.
Topics: Adult; Aged; Antioxidants; Atorvastatin; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Muscular Diseases; Prospective Studies; Pyrroles; Selenium; Surveys and Questionnaires; Treatment Outcome; Ubiquinone; Vitamins | 2013 |
No effect of atorvastatin and simvastatin on oxidative stress in patients at high risk for cardiovascular disease.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Atorvastatin; Cardiovascular Diseases; Cholesterol, LDL; Deoxyguanosine; F2-Isoprostanes; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Peroxidase; Pyrroles; Simvastatin; Ubiquinone | 2013 |
Effect of a hydrophilic and a hydrophobic statin on cardiac salvage after ST-elevated acute myocardial infarction - a pilot study.
Topics: Aged; Atorvastatin; Cholesterol, LDL; Echocardiography; Fatty Acids; Female; Fluorobenzenes; Heart; Heptanoic Acids; Humans; Hydrophobic and Hydrophilic Interactions; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iodobenzenes; Male; Middle Aged; Myocardial Infarction; Myocardium; Natriuretic Peptide, Brain; Pilot Projects; Prospective Studies; Pyrimidines; Pyrroles; Radionuclide Imaging; Rosuvastatin Calcium; Sulfonamides; Thallium; Tomography, Emission-Computed, Single-Photon; Ubiquinone | 2014 |
Coenzyme Q10 in acute influenza.
Topics: Acute Disease; Adult; Atorvastatin; Biomarkers; Double-Blind Method; Female; Humans; Inflammation; Influenza, Human; Male; Middle Aged; Severity of Illness Index; Statistics, Nonparametric; Tertiary Care Centers; Ubiquinone; Young Adult | 2019 |
35 other study(ies) available for atorvastatin and ubiquinone
| Article | Year |
|---|---|
Statins lower plasma and lymphocyte ubiquinol/ubiquinone without affecting other antioxidants and PUFA.
Topics: Antioxidants; Atorvastatin; Catalase; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coenzymes; Erythrocytes; Fatty Acids, Unsaturated; Glutathione; Glutathione Peroxidase; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lymphocytes; Male; Middle Aged; Pravastatin; Pyrroles; Simvastatin; Superoxide Dismutase; Ubiquinone; Vitamin E | 2003 |
Statin cardiomyopathy? A potential role for Co-Enzyme Q10 therapy for statin-induced changes in diastolic LV performance: description of a clinical protocol.
Topics: Atorvastatin; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Protocols; Clinical Trials as Topic; Coenzymes; Diastole; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Ubiquinone; Ventricular Dysfunction, Left | 2003 |
Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke.
Topics: Aged; Analysis of Variance; Atorvastatin; Cardiovascular Diseases; Coenzymes; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Pyrroles; Risk Factors; Stroke; Ubiquinone | 2004 |
Statin-associated exacerbation of myasthenia gravis.
Topics: Atorvastatin; Cytokines; Dysarthria; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Lovastatin; Male; Middle Aged; Mitochondria; Models, Neurological; Muscular Diseases; Myasthenia Gravis; Neural Conduction; Pravastatin; Pyridostigmine Bromide; Pyrroles; Simvastatin; Th2 Cells; Ubiquinone | 2004 |
Chinese red rice depletes muscle coenzyme Q10 and maintains muscle damage after discontinuation of statin treatment.
Topics: Aged; Ascomycota; Atorvastatin; Biological Products; Coenzymes; Creatine Kinase; Dietary Supplements; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Muscle Weakness; Muscle, Skeletal; Pyrroles; Ubiquinone | 2006 |
Herbicidal effects of statin pharmaceuticals in Lemna gibba.
Topics: Atorvastatin; Chromatography, High Pressure Liquid; Heptanoic Acids; Herbicides; Hydroxymethylglutaryl CoA Reductases; Lovastatin; Mevalonic Acid; Models, Chemical; Pharmaceutical Preparations; Plants; Plastoquinone; Pyrroles; Risk Assessment; Sitosterols; Sterols; Ubiquinone; Ultraviolet Rays | 2006 |
Effect of atorvastatin withdrawal on circulating coenzyme Q10 concentration in patients with hypercholesterolemia.
Topics: Atorvastatin; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coenzymes; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Substance Withdrawal Syndrome; Triglycerides; Ubiquinone | 2006 |
Atorvastatin-induced changes in plasma coenzyme q10 and brain natriuretic peptide in patients with coronary artery disease.
Topics: Aged; Atorvastatin; Chromatography, High Pressure Liquid; Coronary Artery Disease; Dose-Response Relationship, Drug; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoassay; Natriuretic Peptide, Brain; Oxidative Stress; Pyrroles; Treatment Outcome; Ubiquinone | 2008 |
Differential effects of statins on endogenous H2S formation in perivascular adipose tissue.
Topics: Adipose Tissue; Animals; Aorta, Thoracic; Atorvastatin; Cholesterol; Cholesterol, HDL; Dose-Response Relationship, Drug; Heptanoic Acids; Hydrogen Sulfide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; KATP Channels; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Potassium Channel Blockers; Pravastatin; Pyrroles; Quinone Reductases; Rats; Rats, Wistar; Sulfides; Triglycerides; Ubiquinone; Vasoconstrictor Agents; Vasodilation | 2011 |
Combined atorvastatin and coenzyme Q10 improve the left ventricular function in isoproterenol-induced heart failure in rat.
Topics: Animals; Atorvastatin; Body Weight; Drug Interactions; Heart Failure; Hemodynamics; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoproterenol; Male; Myocardium; Organ Size; Pyrroles; Rats; Rats, Wistar; Ubiquinone; Ventricular Dysfunction, Left | 2011 |
Coenzyme Q10 and cognition in atorvastatin treated dogs.
Topics: Aging; Animals; Atorvastatin; Cognition Disorders; Dogs; Female; Heptanoic Acids; Male; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; Parietal Lobe; Pyrroles; Ubiquinone | 2011 |
Effects of atorvastatin on heart mitochondrial function and coenzyme Q content in the experiment.
Topics: Animals; Atorvastatin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Mitochondria, Heart; Pyrroles; Rats; Rats, Wistar; Ubiquinone | 2011 |
Liver mitochondrial respiratory function and coenzyme Q content in rats on a hypercholesterolemic diet treated with atorvastatin.
Topics: Animals; Atorvastatin; Cholesterol; Diet; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Male; Micronutrients; Mitochondria, Liver; Pyrroles; Rats; Ubiquinone | 2012 |
Coenzyme Q10 reverses mitochondrial dysfunction in atorvastatin-treated mice and increases exercise endurance.
Topics: Animals; Atorvastatin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mitochondria, Muscle; Muscle Cells; Muscle Strength; Muscle, Skeletal; Organ Size; Oxygen Consumption; Physical Conditioning, Animal; Physical Endurance; Pravastatin; Pyrroles; Ubiquinone | 2012 |
[Effects of atorvastatin and CoQ(10) on myocardial energy metabolism in rabbits with hypercholesterolemia].
Topics: Animals; Atorvastatin; Energy Metabolism; Heptanoic Acids; Hypercholesterolemia; Male; Mitochondria, Heart; Myocardium; Pyrroles; Rabbits; Ubiquinone | 2012 |
[Myopathy due to deficiency of desaminase myoadenilate induced by atorvastatine].
Topics: Aged; Amino Acid Substitution; AMP Deaminase; Atorvastatin; Biopsy; Causality; Creatine Kinase, MM Form; Exercise Tolerance; Female; Heptanoic Acids; Homozygote; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver-Specific Organic Anion Transporter 1; Mitochondria, Muscle; Models, Genetic; Muscle, Skeletal; Mutation, Missense; Myalgia; Organic Anion Transporters; Parkinsonian Disorders; Point Mutation; Polymorphism, Single Nucleotide; Purine-Pyrimidine Metabolism, Inborn Errors; Pyrroles; Ubiquinone | 2013 |
Atorvastatin reduces the myocardial content of coenzyme Q10 in isoproterenol-induced heart failure in rats.
Topics: Animals; Antioxidants; Atorvastatin; Heart Failure; Heptanoic Acids; Isoproterenol; Lipid Peroxidation; Lipids; Male; Malondialdehyde; Myocardium; Pyrroles; Rats; Rats, Wistar; Ubiquinone | 2014 |
Coenzyme Q10 supplementation improves metabolic parameters, liver function and mitochondrial respiration in rats with high doses of atorvastatin and a cholesterol-rich diet.
Topics: Animals; Atorvastatin; Cell Respiration; Cholesterol, Dietary; Cholesterol, HDL; Diet, High-Fat; Dietary Supplements; Drug Evaluation, Preclinical; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Liver; Male; Mitochondria, Liver; Pyrroles; Rats; Rats, Wistar; Triglycerides; Ubiquinone | 2014 |
Efficiency of hepatocyte pretreatment with coenzyme Q10 against statin toxicity.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Cell Survival; Hepatocytes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lethal Dose 50; Lipid Peroxidation; Lovastatin; Male; Membrane Potentials; Mitochondria; Protective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Simvastatin; Ubiquinone | 2014 |
Red yeast rice and coenzyme Q10 as safe alternatives to surmount atorvastatin-induced myopathy in hyperlipidemic rats.
Topics: Animals; Aorta; Atorvastatin; Biological Products; Combined Modality Therapy; Creatine Kinase; Diet, High-Fat; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipoproteins; Liver; Male; Muscular Diseases; Myocardium; Pyrroles; Rats; Ubiquinone | 2014 |
Statin adverse effects: sorting out the evidence.
Topics: Atorvastatin; Clinical Trials as Topic; Drug Monitoring; Drug-Related Side Effects and Adverse Reactions; Evidence-Based Practice; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Outcome Assessment, Health Care; Practice Guidelines as Topic; Pyrroles; Rhabdomyolysis; Risk Adjustment; Ubiquinone; Vitamins | 2014 |
Does coenzyme-Q have a protective effect against atorvastatin induced myopathy? A histopathological and immunohistochemical study in albino rats.
Topics: Animals; Atorvastatin; bcl-2-Associated X Protein; Creatine Kinase; Cytochromes c; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Male; Muscle, Skeletal; Muscular Diseases; Protective Agents; Pyrroles; Rats; Ubiquinone | 2015 |
L-Carnitine, but not coenzyme Q10, enhances the anti-osteoporotic effect of atorvastatin in ovariectomized rats.
Topics: Animals; Atorvastatin; Bone Density; Bone Density Conservation Agents; Carnitine; Dose-Response Relationship, Drug; Drug Synergism; Female; Osteoporosis; Ovariectomy; Radiography; Rats; Rats, Sprague-Dawley; Treatment Outcome; Ubiquinone | 2016 |
Elucidation of the mechanism of atorvastatin-induced myopathy in a rat model.
Topics: Adenosine Triphosphate; Animals; Atorvastatin; Creatine Kinase; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Lactic Acid; Male; Microscopy, Electron, Transmission; Mitochondria, Muscle; Motor Activity; Muscle, Skeletal; Muscular Diseases; Myoglobin; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Ubiquinone | 2016 |
Coenzyme Q10 Prevents Mitochondrial Dysfunction and Facilitates Pharmacological Activity of Atorvastatin in 6-OHDA Induced Dopaminergic Toxicity in Rats.
Topics: Animals; Antioxidants; Atorvastatin; Caspase 3; Caspase 9; Corpus Striatum; Dopamine; Dopaminergic Neurons; Drug Synergism; Electron Transport Complex IV; Male; Membrane Potential, Mitochondrial; Mice; Mitochondria; Motor Activity; Motor Skills; Oxidative Stress; Oxidopamine; Pars Compacta; Ubiquinone | 2017 |
Coenzyme Q10 protects against statin-induced myotoxicity in zebrafish larvae (Danio rerio).
Topics: Animals; Atorvastatin; F-Box Proteins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Larva; Locomotion; Muscle Proteins; Muscular Diseases; Protective Agents; RNA, Messenger; Transcription Factors; Ubiquinone; Zebrafish; Zebrafish Proteins | 2017 |
Polypharmacy and sun exposure: Implications for mitochondrial DNA deletions in skin.
Topics: Aged; Allopurinol; Atorvastatin; Bisoprolol; Cholesterol; DNA Damage; DNA, Mitochondrial; Gene Deletion; Humans; Mitochondria; Perindopril; Pravastatin; Real-Time Polymerase Chain Reaction; Skin; Ubiquinone; Ultraviolet Rays | 2017 |
Coenzyme Q10 supplementation improves acute outcomes of stroke in rats pretreated with atorvastatin.
Topics: Animals; Apoptosis; Atorvastatin; Brain Ischemia; Encephalitis; Male; Neuroprotective Agents; Oxidative Stress; Rats, Wistar; Stroke; Treatment Outcome; Ubiquinone | 2019 |
Atorvastatin in nano-particulate formulation abates muscle and liver affliction when coalesced with coenzyme Q10 and/or vitamin E in hyperlipidemic rats.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Atorvastatin; Drug Compounding; Hyperlipidemias; Liver; Male; Muscles; Nanoparticles; Oxidative Stress; Rats; Rats, Wistar; Ubiquinone; Vitamin E; Vitamins | 2018 |
A novel investigation of statins myotoxic mechanism: effect of atorvastatin on respiratory muscles in hypoxic environment.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Hypoxia; Male; Muscle Contraction; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Ubiquinone | 2019 |
Letter to the editor concerning coenzyme Q10 supplementation improves acute outcomes of stroke in rats pretreated with atorvastatin.
Topics: Animals; Atorvastatin; Dietary Supplements; Rats; Stroke; Ubiquinone | 2021 |
The particulars of certain drugs' effect on the endogenous coenzyme Q10 plasma level in patients with cardiovascular diseases.
Topics: Amlodipine; Atorvastatin; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Tandem Mass Spectrometry; Ubiquinone | 2020 |
Association of statin induced reduction in serum coenzyme Q10 level and conduction deficits in motor and sensory nerves: An observational cross-sectional study.
Topics: Atorvastatin; Cross-Sectional Studies; Dyslipidemias; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Neural Conduction; Peripheral Nervous System Diseases; Rosuvastatin Calcium; Ubiquinone | 2020 |
Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected.
Topics: Animals; Atorvastatin; Biomarkers; Cell Respiration; Citrate (si)-Synthase; Hydrogen Peroxide; Male; Metabolome; Mitochondria, Heart; Mitochondria, Liver; Mitochondria, Muscle; Obesity; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Swine; Swine, Miniature; Ubiquinone | 2021 |
Evaluation of coenzyme Q10 combined with or without N-acetyl cysteine or atorvastatin for preventing contrast-induced kidney injury in diabetic rats.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Atorvastatin; Contrast Media; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Drug Therapy, Combination; Male; Rats; Rats, Sprague-Dawley; Ubiquinone | 2021 |