Page last updated: 2024-08-24

atorvastatin and piperidines

atorvastatin has been researched along with piperidines in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (31.25)29.6817
2010's9 (56.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Amano, Y; Imura, Y; Ishikawa, E; Nishimoto, T; Sugiyama, Y; Tozawa, Ri1
Cassels, A; Cole, C; Hughes, MA; Lexchin, J; McCormack, JP; Mintzes, B1
Breazna, A; Doody, R; Feldman, H; Hey-Hadavi, J; Jones, RW; Kivipelto, M; Ramos, H; Schindler, RJ; Sparks, L; Waters, DD1
Sabbagh, MN1
Backman, JT; Kalliokoski, A; Kurkinen, KJ; Neuvonen, PJ; Niemi, M1
MacMillan, DW; Nagib, DA1
Reddy, PJ; Sekhar, MC1
Bush, M; Collins, D; Generaux, G; Hussey, E; McMullen, S; Nunez, DJ; Polli, JW; Smith, G; Turner, N1
Bradley, JD; Brosnan, MJ; Connell, CA; Kim, HY; Lee, SH; Luo, Z; Mandel, D; McInnes, IB; Song, YW; Zuckerman, A; Zwillich, SH1
Cardona-Gómez, GP; Garcia-Segura, LM; Gutierrez-Vargas, JA; Muñoz-Manco, JI1
Burger, D; Maliepaard, M; Neef, C; Teerenstra, S; Yu, Y1
Chen, IJ; Dai, ZK; Hsu, JH; Liou, SF; Wu, BN; Wu, JR; Yeh, JL1
Barton, HA; Li, R1
Gonzalez, CG; Hernandez, JA; Quintana, AM1
Choudhary, DC; Nagrik, SS; Raje, A; Thomas, AB1
Nanjappan, SK; Ravichandiran, V; Somabattini, RA1

Trials

4 trial(s) available for atorvastatin and piperidines

ArticleYear
The Atorvastatin/Donepezil in Alzheimer's Disease Study (LEADe): design and baseline characteristics.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2008, Volume: 4, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anticholesteremic Agents; Atorvastatin; Cholinesterase Inhibitors; Donepezil; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Indans; Lipids; Male; Middle Aged; Piperidines; Pyrroles

2008
Effects of gemfibrozil and atorvastatin on the pharmacokinetics of repaglinide in relation to SLCO1B1 polymorphism.
    Clinical pharmacology and therapeutics, 2008, Volume: 84, Issue:4

    Topics: Administration, Oral; Adult; Area Under Curve; Atorvastatin; Blood Glucose; Carbamates; Cross-Over Studies; Drug Interactions; Female; Gemfibrozil; Genotype; Half-Life; Heptanoic Acids; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Liver-Specific Organic Anion Transporter 1; Male; Organic Anion Transporters; Piperidines; Polymorphism, Genetic; Pyrroles

2008
Evaluation of drug interactions of GSK1292263 (a GPR119 agonist) with statins: from in vitro data to clinical study design.
    Xenobiotica; the fate of foreign compounds in biological systems, 2013, Volume: 43, Issue:6

    Topics: Adolescent; Adult; Aged; Animals; Atorvastatin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Demography; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Madin Darby Canine Kidney Cells; Male; Mesylates; Middle Aged; Oxadiazoles; Piperidines; Pyrimidines; Pyrroles; Reference Standards; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Troleandomycin; Young Adult

2013
Open-label tofacitinib and double-blind atorvastatin in rheumatoid arthritis patients: a randomised study.
    Annals of the rheumatic diseases, 2014, Volume: 73, Issue:1

    Topics: Administration, Oral; Adult; Arthritis, Rheumatoid; Atorvastatin; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Middle Aged; Piperidines; Placebos; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Treatment Outcome

2014

Other Studies

12 other study(ies) available for atorvastatin and piperidines

ArticleYear
Lipid-lowering effects of TAK-475, a squalene synthase inhibitor, in animal models of familial hypercholesterolemia.
    European journal of pharmacology, 2003, Apr-11, Volume: 466, Issue:1-2

    Topics: Administration, Oral; Animals; Atorvastatin; Cholesterol, HDL; Disease Models, Animal; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Male; Mice; Mice, Knockout; Oxazepines; Piperidines; Pyrroles; Rabbits; Receptors, LDL; Simvastatin; Species Specificity; Time Factors; Triglycerides

2003
Drugs in the news: an analysis of Canadian newspaper coverage of new prescription drugs.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2003, Apr-29, Volume: 168, Issue:9

    Topics: Acetamides; Advertising; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antiviral Agents; Atorvastatin; Bibliometrics; Canada; Celecoxib; Cholinesterase Inhibitors; Consumer Product Safety; Disclosure; Donepezil; Drug Industry; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Estrogen Antagonists; Heptanoic Acids; Humans; Indans; Newspapers as Topic; Oseltamivir; Patient Education as Topic; Piperidines; Pyrazoles; Pyrroles; Raloxifene Hydrochloride; Sulfonamides

2003
Commentary on "the Atorvastatin/Donepezil in Alzheimer's Disease Study (LEADe): design and baseline characteristics".
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2008, Volume: 4, Issue:3

    Topics: Alzheimer Disease; Anticholesteremic Agents; Atorvastatin; Cholinesterase Inhibitors; Donepezil; Drug Therapy, Combination; Heptanoic Acids; Humans; Indans; Multicenter Studies as Topic; Piperidines; Pyrroles; Randomized Controlled Trials as Topic

2008
Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis.
    Nature, 2011, Dec-08, Volume: 480, Issue:7376

    Topics: Anticholesteremic Agents; Atorvastatin; Catalysis; Chemistry Techniques, Synthetic; Cholinesterase Inhibitors; Donepezil; Drug Design; Flavones; Halogenation; Heptanoic Acids; Indans; Isomerism; Light; Methylation; Molecular Structure; Oxidation-Reduction; Pharmaceutical Preparations; Photochemical Processes; Piperidines; Pyrroles; Uracil

2011
Influence of atorvastatin on the pharmacodynamic and pharmacokinetic activity of repaglinide in rats and rabbits.
    Molecular and cellular biochemistry, 2012, Volume: 364, Issue:1-2

    Topics: Animals; Atorvastatin; Blood Glucose; Carbamates; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Diabetes Mellitus, Experimental; Drug Interactions; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Piperidines; Pyrroles; Rabbits; Rats

2012
GluN2B N-methyl-D-aspartic acid receptor subunit mediates atorvastatin-Induced neuroprotection after focal cerebral ischemia.
    Journal of neuroscience research, 2014, Volume: 92, Issue:11

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Embryo, Mammalian; Heptanoic Acids; Male; Maze Learning; Nerve Tissue Proteins; Nervous System Diseases; Piperidines; Platelet Aggregation Inhibitors; Pyrroles; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recovery of Function; Somatosensory Cortex; Time Factors

2014
Investigation into the interchangeability of generic formulations using immunosuppressants and a broad selection of medicines.
    European journal of clinical pharmacology, 2015, Volume: 71, Issue:8

    Topics: Anilides; Area Under Curve; Atorvastatin; Benzodiazepines; Chemistry, Pharmaceutical; Cyclosporine; Drugs, Generic; Humans; Immunosuppressive Agents; Mycophenolic Acid; Nitriles; Olanzapine; Perindopril; Piperidines; Tacrolimus; Therapeutic Equivalency; Tosyl Compounds; Tryptamines; Venlafaxine Hydrochloride

2015
Activation of endothelial NO synthase by a xanthine derivative ameliorates hypoxia-induced apoptosis in endothelial progenitor cells.
    The Journal of pharmacy and pharmacology, 2016, Volume: 68, Issue:6

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Atorvastatin; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Cytoprotection; Endothelial Progenitor Cells; Enzyme Activation; Enzyme Activators; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Phosphorylation; Piperidines; Rats, Sprague-Dawley; Signal Transduction; Simvastatin; Xanthines

2016
Explaining Ethnic Variability of Transporter Substrate Pharmacokinetics in Healthy Asian and Caucasian Subjects with Allele Frequencies of OATP1B1 and BCRP: A Mechanistic Modeling Analysis.
    Clinical pharmacokinetics, 2018, Volume: 57, Issue:4

    Topics: Asian People; Atorvastatin; ATP Binding Cassette Transporter, Subfamily G, Member 2; Carbamates; Computer Simulation; Gene Frequency; Genotype; Healthy Volunteers; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Liver-Specific Organic Anion Transporter 1; Models, Biological; Neoplasm Proteins; Pharmacogenomic Variants; Phenotype; Piperidines; Pravastatin; Quinolines; Rosuvastatin Calcium; White People

2018
Functional analysis of the zebrafish ortholog of HMGCS1 reveals independent functions for cholesterol and isoprenoids in craniofacial development.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Benzophenones; Body Patterning; Cell Differentiation; Cholesterol; Chondrocytes; Craniofacial Abnormalities; Embryo, Nonmammalian; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Hedgehog Proteins; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Neural Crest; Piperidines; Pyridines; Signal Transduction; Terpenes; Zebrafish; Zebrafish Proteins; Zinc Finger Protein GLI1

2017
Pharmacokinetics and Pharmacodynamic Herb-Drug Interaction of Piperine with Atorvastatin in Rats.
    Journal of chromatographic science, 2021, Mar-19, Volume: 59, Issue:4

    Topics: Alkaloids; Animals; Atorvastatin; Benzodioxoles; Chromatography, High Pressure Liquid; Herb-Drug Interactions; Limit of Detection; Linear Models; Piperidines; Plant Extracts; Polyunsaturated Alkamides; Rats; Rats, Wistar; Reproducibility of Results

2021
Investigation of the effect of Acai berry on the pharmacokinetics of Atorvastatin, Alogliptin and Empagliflozin: a herb-drug interaction study.
    The Journal of pharmacy and pharmacology, 2022, Aug-19, Volume: 74, Issue:8

    Topics: Animals; Atorvastatin; Benzhydryl Compounds; Euterpe; Glucosides; Herb-Drug Interactions; Piperidines; Rats; Rats, Sprague-Dawley; Uracil

2022