atorvastatin has been researched along with pioglitazone in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (40.00) | 29.6817 |
| 2010's | 16 (53.33) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Alsheikh-Ali, AA; Karas, RH | 1 |
| Miyashita, Y; Murano, T; Oyama, T; Saiki, A; Shirai, K; Watanabe, F | 1 |
| Atar, S; Birnbaum, Y; Huang, MH; Lin, Y; Perez-Polo, JR; Uretsky, BF; Ye, Y | 1 |
| Birnbaum, Y; Freeberg, SY; Huang, MH; Lin, Y; Martinez, JD; Nishi, SP; Perez-Polo, JR; Uretsky, BF; Ye, Y | 1 |
| Birnbaum, Y; Freeberg, SY; Huang, MH; Lin, Y; Perez-Polo, JR; Uretsky, BF; Ye, Y | 1 |
| Birnbaum, Y; Huang, MH; Lin, Y; Manickavasagam, S; Nishi, SP; Perez-Polo, JR; Uretsky, BF; Ye, Y | 1 |
| Lindberg, MB; Ohman, KP; Ose, L; Retterstøl, K; Svensson, M; Tonstad, S | 1 |
| Baxi, H; Chag, M; Chandarana, A; Goyal, R; Mehta, A; Naik, A; Parikh, K; Shah, K; Shah, U | 1 |
| Birnbaum, Y; Lin, Y; Perez-Polo, JR; Tieu, BC; Uretsky, BF; Ye, Y; Ye, Z | 1 |
| Forst, T; Fuchs, W; Hanefeld, M; Konrad, T; Lehmann, U; Müller, J; Pfützner, A; Schaper, F; Weber, M; Wilhelm, B | 1 |
| Clementi, F; Di Luozzo, M; Luciani, G; Mango, R; Martuscelli, E; Mehta, JL; Pizzuto, F; Romeo, F; Trivisonno, A | 1 |
| Shinohara, Y | 1 |
| El-Moselhy, MA; Heeba, GH; Mourad, AA; Taye, A | 1 |
| Dhull, P; Kumar, KV; Patnaik, SK; Upreti, V | 1 |
| Chen, HL; Dang, HW; Wang, XY; Yang, FY; Yang, WC; Zhang, WP | 1 |
| Ammineni, P; Kondreddy, Vk; Mallikarjuna, S; Peraman, R | 1 |
| Khoramjouy, M; Malekinejad, H; Mehrabi, M; Rezaei-Golmisheh, A | 1 |
| Amniattalab, A; Hobbenaghi, R; Khoramjouy, M; Malekinejad, H | 1 |
| Dehpour, A; Jahanabadi, S; Javadi, S; Khoshnoodi, M; Mehr, SE; Shafaroodi, H; Shahsavarian, A; Shamsaee, J | 1 |
| Aggarwal, S; Aslam, M; Galav, V; Madhu, SV; Sharma, KK | 1 |
| Ando, O; Furihata, K; Kusuhara, H; Maeda, K; Nakayama, T; Sugiyama, Y; Takehara, I; Terashima, H; Watanabe, N; Yoshida, M; Yoshikado, T | 1 |
| An, L; Lin, Y; Ma, G; Mu, G; Qian, L; Ren, L; Zhu, K | 1 |
| Awortwe, C; Joubert, E; Louw, J; Muller, CJF; Patel, O; Rosenkranz, B | 1 |
| Chen, X; Liang, Z; Nie, M; Yan, Y; Zhang, X; Zhao, Q | 1 |
2 review(s) available for atorvastatin and pioglitazone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Japanese Guidelines for the Management of Stroke 2009 : important revised points necessary for the neurologist].
Topics: Aspirin; Atorvastatin; Cilostazol; Diabetes Complications; Dyslipidemias; Evidence-Based Medicine; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Japan; Neurology; Physicians; Pioglitazone; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Pyrroles; Secondary Prevention; Stroke; Tetrazoles; Thiazolidinediones; Tissue Plasminogen Activator | 2010 |
3 trial(s) available for atorvastatin and pioglitazone
| Article | Year |
|---|---|
The dual peroxisome proliferator-activated receptor alpha/gamma agonist tesaglitazar further improves the lipid profile in dyslipidemic subjects treated with atorvastatin.
Topics: Adult; Alkanesulfonates; Anticholesteremic Agents; Atorvastatin; Chemotherapy, Adjuvant; Cross-Over Studies; Drug Combinations; Drug Synergism; Dyslipidemias; Female; Heptanoic Acids; Humans; Hypoglycemic Agents; Lipids; Male; Middle Aged; Phenylpropionates; Pioglitazone; Placebos; PPAR alpha; PPAR gamma; Pyrroles; Thiazolidinediones | 2007 |
Effect of pioglitazone and its combination with statins in coronary artery disease patients with hyperinsulinemia.
Topics: Apolipoprotein A-I; Apolipoproteins B; Atorvastatin; Blood Glucose; Body Mass Index; Cholesterol, HDL; Coronary Artery Disease; Diabetes Complications; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Fibrinogen; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Antagonists; Male; Middle Aged; Pioglitazone; Pyrroles; Thiazolidinediones; Treatment Outcome | 2007 |
Investigation of the vascular and pleiotropic effects of atorvastatin and pioglitazone in a population at high cardiovascular risk.
Topics: Aged; Atherosclerosis; Atorvastatin; Blood Pressure; Cardiovascular Diseases; Carotid Artery, Common; Double-Blind Method; Drug Therapy, Combination; Female; Germany; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Lipids; Male; Microcirculation; Middle Aged; Pioglitazone; Prospective Studies; Pyrroles; Radial Artery; Risk Assessment; Skin; Thiazolidinediones; Treatment Outcome; Ultrasonography | 2008 |
25 other study(ies) available for atorvastatin and pioglitazone
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
Adverse events with concomitant use of simvastatin or atorvastatin and thiazolidinediones.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Atorvastatin; Databases, Factual; Drug Interactions; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Male; Middle Aged; Pioglitazone; Pyrroles; Rosiglitazone; Simvastatin; Thiazolidinediones; United States; United States Food and Drug Administration | 2004 |
Pitavastatin enhanced lipoprotein lipase expression in 3T3-L1 preadipocytes.
Topics: 3T3-L1 Cells; Animals; Atorvastatin; Cell Culture Techniques; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoprotein Lipase; Mevalonic Acid; Mice; Pioglitazone; PPAR gamma; Pravastatin; Pyrroles; Quinolines; RNA, Messenger; Simvastatin; Thiazolidinediones | 2005 |
Myocardial protection by pioglitazone, atorvastatin, and their combination: mechanisms and possible interactions.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Synergism; Drug Therapy, Combination; Gene Expression Regulation; Heptanoic Acids; Hypoglycemic Agents; Inositol Polyphosphate 5-Phosphatases; Male; Myocardial Infarction; Nitric Oxide Synthase Type III; Oncogene Protein v-akt; Phospholipases A; Phospholipases A2; Phosphoric Monoester Hydrolases; Phosphorylation; Pioglitazone; PTEN Phosphohydrolase; Pyrazoles; Pyrroles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiazolidinediones | 2006 |
Augmentation of myocardial production of 15-epi-lipoxin-a4 by pioglitazone and atorvastatin in the rat.
Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Heart; Heptanoic Acids; Lipoxins; Models, Animal; Myocardium; Pioglitazone; Pyrroles; Rats; Thiazolidinediones | 2006 |
Aspirin augments 15-epi-lipoxin A4 production by lipopolysaccharide, but blocks the pioglitazone and atorvastatin induction of 15-epi-lipoxin A4 in the rat heart.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atorvastatin; Biotin; Cyclooxygenase 2; Enzyme Induction; Heart; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Lipopolysaccharides; Lipoxins; Male; Myocardium; Nitroso Compounds; Pioglitazone; Pyrroles; Rats; Rats, Sprague-Dawley; Thiazolidinediones | 2007 |
Activation of peroxisome proliferator-activated receptor-gamma (PPAR-gamma) by atorvastatin is mediated by 15-deoxy-delta-12,14-PGJ2.
Topics: Animals; Atorvastatin; CD36 Antigens; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Heptanoic Acids; Models, Biological; Models, Chemical; Myocardium; Pioglitazone; PPAR gamma; Prostaglandin D2; Pyrroles; Rats; Thiazolidinediones; Transcription Factors | 2007 |
Phosphorylation of 5-lipoxygenase at ser523 by protein kinase A determines whether pioglitazone and atorvastatin induce proinflammatory leukotriene B4 or anti-inflammatory 15-epi-lipoxin a4 production.
Topics: Animals; Arachidonate 5-Lipoxygenase; Atorvastatin; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Heptanoic Acids; Immunologic Factors; Isoquinolines; Leukotriene B4; Lipoxins; Male; Myocardium; Phosphorylation; Pioglitazone; Pyrroles; Rats; Rats, Sprague-Dawley; Serine; Sulfonamides; Thiazolidinediones | 2008 |
Regression and shift in composition of coronary atherosclerotic plaques by pioglitazone: insight from an intravascular ultrasound analysis.
Topics: Aged; Atorvastatin; Calcinosis; Coronary Artery Disease; Diabetes Mellitus; Drug Therapy, Combination; Female; Fibrosis; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Male; Middle Aged; Necrosis; Pilot Projects; Pioglitazone; Prospective Studies; Pyrroles; Registries; Thiazolidinediones; Time Factors; Treatment Outcome; Ultrasonography, Interventional; User-Computer Interface | 2009 |
Comparative study between atorvastatin and losartan on high fat diet-induced type 2 diabetes mellitus in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atorvastatin; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diet, High-Fat; Drug Therapy, Combination; Heptanoic Acids; Hypercholesterolemia; Hyperglycemia; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Resistance; Losartan; Male; Obesity; Pioglitazone; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2013 |
An unusual cause of delayed puberty: Berardinelli- Seip syndrome.
Topics: Administration, Cutaneous; Adolescent; Atorvastatin; Combined Modality Therapy; Diet, Fat-Restricted; Drug Therapy, Combination; Estrogens; Exercise Therapy; Female; Fenofibrate; Fish Oils; Heptanoic Acids; Humans; Hypertension, Portal; Hypertriglyceridemia; Insulin; Insulin Resistance; Lipodystrophy, Congenital Generalized; Pioglitazone; Propranolol; Puberty, Delayed; Pyrroles; Thiazolidinediones; Treatment Outcome | 2012 |
[Pharmacokinetic interaction of pioglitazone hydrochloride and atorvastatin calcium in Beagle dogs].
Topics: Administration, Oral; Animals; Anticholesteremic Agents; Area Under Curve; Atorvastatin; Biological Availability; Cross-Over Studies; Dogs; Drug Interactions; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Male; Pioglitazone; Random Allocation; Thiazolidinediones | 2013 |
RP-HPLC method development and validation for simultaneous estimation of atorvastatin calcium and pioglitazone hydrochloride in pharmaceutical dosage form.
Topics: Atorvastatin; Calibration; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Dosage Forms; Drug Combinations; Heptanoic Acids; Hydrogen-Ion Concentration; Limit of Detection; Phosphoric Acids; Pioglitazone; Pyrroles; Reproducibility of Results; Thiazolidinediones | 2014 |
Antifibrotic effect of atorvastatin on paraquat-induced pulmonary fibrosis: role of PPARγ receptors.
Topics: Anilides; Animals; Atorvastatin; Body Weight; Heptanoic Acids; Herbicides; Hydroxyproline; Lung; Male; Organ Size; Paraquat; Pioglitazone; PPAR gamma; Protective Agents; Pulmonary Fibrosis; Pyrroles; Rats; Rats, Wistar; RNA, Messenger; Thiazolidinediones; Transforming Growth Factor beta1 | 2013 |
Atorvastatin attenuates the paraquat-induced pulmonary inflammation via PPARγ receptors: a new indication for atorvastatin.
Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Heptanoic Acids; Herbicides; Interleukin-6; Lung; Male; Malondialdehyde; Nitric Oxide; Paraquat; Peroxidase; Pioglitazone; Pneumonia; PPAR gamma; Pyrroles; Rats, Wistar; Thiazolidinediones; Tumor Necrosis Factor-alpha; Weight Loss | 2014 |
Antidepressant-like effect of atorvastatin in the forced swimming test in mice: the role of PPAR-gamma receptor and nitric oxide pathway.
Topics: Anilides; Animals; Antidepressive Agents; Atorvastatin; Depression; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipramine; Male; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pioglitazone; PPAR gamma; Pyrroles; Signal Transduction; Swimming; Thiazolidinediones | 2014 |
Postprandial Hypertriglyceridemia Predicts Development of Insulin Resistance Glucose Intolerance and Type 2 Diabetes.
Topics: Animals; Atorvastatin; Blood Glucose; Body Weight; Causality; Diabetes Mellitus, Type 2; Dietary Fats; Dietary Sucrose; Disease Progression; Glucose Intolerance; Glucose Tolerance Test; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; Hypoglycemic Agents; Insulin Resistance; Intra-Abdominal Fat; Lipids; Liver; Male; Pancreas; Pioglitazone; Postprandial Period; Prediabetic State; Random Allocation; Rats; Rats, Wistar; Thiazolidinediones | 2016 |
Investigation of Glycochenodeoxycholate Sulfate and Chenodeoxycholate Glucuronide as Surrogate Endogenous Probes for Drug Interaction Studies of OATP1B1 and OATP1B3 in Healthy Japanese Volunteers.
Topics: Adult; Atorvastatin; Bile Acids and Salts; Chenodeoxycholic Acid; Drug Interactions; Glucuronides; Glycochenodeoxycholic Acid; HEK293 Cells; Hepatocytes; Humans; Liver-Specific Organic Anion Transporter 1; Male; Organic Anion Transporters, Sodium-Dependent; Pioglitazone; Rifampin; Solute Carrier Organic Anion Transporter Family Member 1B3; Symporters; Taurocholic Acid; Thiazolidinediones; Young Adult | 2017 |
Pioglitazone Ameliorates Atorvastatin-Induced Islet Cell Dysfunction through Activation of FFA1 in INS-1 Cells.
Topics: Animals; Atorvastatin; Basic Helix-Loop-Helix Transcription Factors; Cell Line; Homeodomain Proteins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Nerve Tissue Proteins; Pioglitazone; Rats; Receptors, G-Protein-Coupled; Trans-Activators | 2019 |
Therapeutic effects of an aspalathin-rich green rooibos extract, pioglitazone and atorvastatin combination therapy in diabetic db/db mice.
Topics: Animals; Aspalathus; Atorvastatin; Blood Glucose; Chalcones; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glucose; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Liver; Male; Mice; Mice, Inbred Strains; Phytotherapy; Pioglitazone; Plant Extracts | 2021 |
Pioglitazone combined with atorvastatin promotes plaque stabilization in a rabbit model.
Topics: Animals; Atherosclerosis; Atorvastatin; C-Reactive Protein; Cholesterol, HDL; Cholesterol, LDL; Matrix Metalloproteinase 9; Pioglitazone; Plaque, Atherosclerotic; Rabbits; Triglycerides | 2022 |