Page last updated: 2024-08-24

atorvastatin and monocrotaline

atorvastatin has been researched along with monocrotaline in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's5 (45.45)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Bardou, M; Dumas, M; Goirand, F; Guerard, P; Lirussi, F; Rakotoniaina, Z; Rochette, L2
Archer, SL; Bonnet, S; Haromy, A; McMurtry, MS; Michelakis, ED1
Satoh, A; Satoh, M1
Ozturk, EI; Uma, S1
Fan, ZX; Gao, YF; Jing, ZC; Li, J; Li, L; Ma, D; Shi, DM; Wang, YW; Wu, BX; Zhu, XD1
Lin, P; Xie, H; Xie, L; Xu, C1
Chen, D; Chen, F; Dong, L; Ge, J; Guan, L; Qian, J; Zhou, D1
Cai, X; Huang, X; Jiang, Z; Lin, Z; Wang, H; Xie, L1
Dong, S; Feng, Y; Jiang, Q; Li, J; Li, S; Li, T; Lin, W; Liu, B; Luo, H; Ou, Z; Qi, Q; Xu, Q; Yu, Z; Zeng, X; Zha, L; Zhang, M; Zhao, L1
Gao, G; Lian, G; Lin, T; Luo, L; Wang, H; Wu, J; Xie, L1

Other Studies

11 other study(ies) available for atorvastatin and monocrotaline

ArticleYear
The protective effect of HMG-CoA reductase inhibitors against monocrotaline-induced pulmonary hypertension in the rat might not be a class effect: comparison of pravastatin and atorvastatin.
    Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 374, Issue:3

    Topics: Acetylcholine; Animals; Apoptosis; Atorvastatin; Caspase 3; Endothelial Cells; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Nitric Oxide Synthase Type III; Nitroprusside; Pravastatin; Pulmonary Artery; Pyrroles; Rats; Rats, Wistar; Ventricular Pressure

2006
Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study.
    American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 293, Issue:4

    Topics: Animals; Atorvastatin; Blood Pressure; Disease Progression; Dose-Response Relationship, Drug; Drug Synergism; Echocardiography; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Male; Monocrotaline; Phosphorylation; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Simvastatin; Sirolimus

2007
Celecoxib but not the combination of celecoxib+atorvastatin prevents the development of monocrotaline-induced pulmonary hypertension in the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:3

    Topics: Acetylcholine; Animals; Atorvastatin; Blotting, Western; Body Weight; Caspase 3; Celecoxib; Cyclooxygenase Inhibitors; Disease Progression; Drug Combinations; Hemodynamics; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Nitric Oxide Synthase Type III; Pulmonary Artery; Pyrazoles; Pyrroles; Rats; Rats, Wistar; Sulfonamides; Survival Analysis; Vasodilator Agents

2008
3-Hydroxy-3-methylglutaryl (HMG)-COA reductase inhibitors and phosphodiesterase type V inhibitors attenuate right ventricular pressure and remodeling in a rat model of pulmonary hypertension.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2009, Feb-04, Volume: 11, Issue:2

    Topics: Animals; Atorvastatin; Disease Models, Animal; Hemodynamics; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Male; Monocrotaline; Phosphodiesterase Inhibitors; Pravastatin; Pulmonary Artery; Pyrroles; Rats; Rats, Wistar; Simvastatin

2009
Effects of atorvastatin and L-arginine treatments on electrical field stimulation-mediated relaxations in pulmonary arterial rings of monocrotaline-induced pulmonary hypertensive rats.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:5

    Topics: Animals; Arginine; Atorvastatin; Electric Stimulation; Endothelium, Vascular; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; In Vitro Techniques; Male; Monocrotaline; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Vasodilation

2010
The effects of atorvastatin on pulmonary arterial hypertension and expression of p38, p27, and Jab1 in rats.
    International journal of molecular medicine, 2010, Volume: 26, Issue:4

    Topics: Animals; Atorvastatin; COP9 Signalosome Complex; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Intracellular Signaling Peptides and Proteins; Male; Monocrotaline; p38 Mitogen-Activated Protein Kinases; Pneumonectomy; Proliferating Cell Nuclear Antigen; Proteins; Pulmonary Artery; Pyrroles; Rats; Rats, Wistar

2010
Effects of atorvastatin and losartan on monocrotaline-induced pulmonary artery remodeling in rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2010, Volume: 32, Issue:8

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arterioles; Atorvastatin; Base Sequence; Calcium Channels, L-Type; Disease Models, Animal; DNA Primers; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Inositol 1,4,5-Trisphosphate Receptors; Losartan; Male; Monocrotaline; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases

2010
Atorvastatin prevents dehydromonocrotaline-induced pulmonary hypertension in beagles.
    Experimental lung research, 2012, Volume: 38, Issue:7

    Topics: Alkylating Agents; Animals; Atorvastatin; Cell Proliferation; Cytokines; Dogs; Endothelium, Vascular; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type III; Pyrroles

2012
Preventive treatment with atorvastatin ameliorates endothelial dysfunction of small pulmonary arteries in monocrotaline-induced pulmonary hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2017, Volume: 39, Issue:6

    Topics: Animals; Atorvastatin; Endothelium; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pulmonary Artery; Pulmonary Wedge Pressure; Random Allocation; Rats; Rats, Sprague-Dawley; Vasodilation

2017
Combination of Dichloroacetate and Atorvastatin Regulates Excessive Proliferation and Oxidative Stress in Pulmonary Arterial Hypertension Development via p38 Signaling.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Animals; Apoptosis; Atorvastatin; Cardiomegaly; Cell Proliferation; Cell Survival; Dichloroacetic Acid; Endoplasmic Reticulum Stress; Hemodynamics; Inflammation; Macrophages; Male; Mitochondria; Models, Biological; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pulmonary Arterial Hypertension; Rats, Sprague-Dawley; Signal Transduction

2020
Influence of atorvastatin on metabolic pattern of rats with pulmonary hypertension.
    Aging, 2021, 04-22, Volume: 13, Issue:8

    Topics: Animals; Arterial Pressure; Atorvastatin; Disease Models, Animal; Fatty Acids; Glycolysis; Humans; Hypertension, Pulmonary; Lung; Male; Metabolomics; Monocrotaline; Oxidation-Reduction; Pulmonary Artery; Rats; Vascular Remodeling

2021