atorvastatin has been researched along with malondialdehyde in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 16 (26.67) | 29.6817 |
| 2010's | 35 (58.33) | 24.3611 |
| 2020's | 9 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baldi, S; Blandizzi, C; Del Tacca, M; L'Abbate, A; Lubrano, V; Natali, A; Palombo, C; Vassalle, C | 1 |
| Nasu, M; Tamura, A; Watanabe, T | 1 |
| Almeida, EA; Carneiro, A; Jorge, M; Jorge, PA; Ozaki, MR | 1 |
| Nosaka, S; Ueki, M; Ushiroyama, T | 1 |
| Błaszczyk, J; Cegliński, T; Grycewicz, J; Irzmański, R; Kowalczyk, E; Kowalski, J; Liban-Gałka, B; Pawlicki, L | 1 |
| Bem, AF; Metzger, IF; Nagassaki, S; Rocha, JB; Sertório, JT; Tanus-Santos, JE | 1 |
| Moulik, N; Patil, N; Rajadhyaksha, G; Save, V | 1 |
| Cetin, A; Igdem, AA; Ozacmak, ID; Ozacmak, VH; Sayan, H | 1 |
| Fang, ZF; Li, XP; Liu, QM; Qiu, SF; Shen, XQ; Zhang, M; Zhao, SP; Zhou, SH | 1 |
| Chae, A; Choi, SH; DeMaria, AN; Messig, M; Miller, E; Nissen, SE; Ntanios, F; Tsimikas, S; Witztum, JL | 1 |
| Ikeda, S; Koga, S; Kohno, S; Miyahara, Y; Oka, H | 1 |
| Gryglewski, R; Hassan, M; Heeba, G; Khalifa, M; Malinski, T; Moselhy, ME | 1 |
| Chen, IJ; Hsieh, SL; Kwan, AL; Lin, HL; Shen, KP; Wu, BN | 1 |
| Antonioli, L; Blandizzi, C; Colucci, R; Daghini, E; Del Tacca, M; Duranti, E; Fornai, M; Ghisu, N; Giannarelli, C; Taddei, S; Versari, D; Virdis, A | 1 |
| Altug, T; Aydin, S; Sozer, V; Uzun, H | 1 |
| Alonso, MJ; Briones, AM; Egido, J; García-Redondo, AB; Hernanz, R; Rodrigues-Díez, RR; Rodríguez-Criado, N; Ruiz-Ortega, M; Salaices, M | 1 |
| Ciralik, H; Gümüşalan, Y; Kilinc, M; Ozbag, D; Toru, H; Yasim, A | 1 |
| Cao, HY; Li, J; Li, ZQ; Pan, W; Sun, YM; Wang, LF | 1 |
| Abd-Elghany, MI; Heeba, GH | 1 |
| Antoniades, C; Antonopoulos, AS; Bakogiannis, C; Casadei, B; Channon, KM; Demosthenous, M; Economopoulos, G; Marinou, K; Miliou, A; Paschalis, A; Psarros, C; Reilly, S; Sfyras, N; Stefanadis, C; Tousoulis, D; Zhang, MH | 1 |
| Jiang, R; Kan, H; Song, W; Xie, Y; Zhao, J | 1 |
| Hassanian, MA; Samy, W | 1 |
| Chen, ZY; Lei, L; Li, LY; Liu, Q; Liu, SN; Shen, ZF; Zhang, N | 1 |
| Ishii, H; Koyasu, M; Matsubara, T; Murohara, T; Shibata, R; Takemoto, K; Uemura, Y; Watarai, M; Yoshikawa, D | 1 |
| Gupta, A; Kalonia, H; Kumar, A; Mishra, J; Sharma, N | 1 |
| Atkin, SL; Coady, AM; Kilpatrick, ES; Sathyapalan, T; Shepherd, J | 1 |
| Atkin, SL; Kilpatrick, ES; Sathyapalan, T; Shepherd, J | 1 |
| Jena, GB; Kushwaha, S; Ramanjaneyulu, SV; Trivedi, PP; Vikram, A | 1 |
| Amini, R; Jahanbakhsh, Z; Mohammadi, MT; Shekarforoush, S | 1 |
| Groenemeijer, M; Nanayakkara, PW; Scheffer, PG; Schindhelm, RK; Simsek, S; Smulders, YM; van Verschuer, VM | 1 |
| Andalib, S; Garjani, A; Khorrami, A; Maleki-Dijazi, N; Shayanfar, A | 1 |
| Dang, XM; Ma, AQ; Yang, L; Zhu, B | 1 |
| Chang, CY; Chang, KC; Chang, RW; Chen, YS; Ko, WJ; Ko, YH; Tsai, PR; Wang, CH; Wang, SS; Young, TH | 1 |
| Amniattalab, A; Hobbenaghi, R; Khoramjouy, M; Malekinejad, H | 1 |
| Akagi, H; Akasaka, T; Imanishi, T; Ino, Y; Kitabata, H; Komukai, K; Kubo, T; Kumiko, H; Matsuo, Y; Okumoto, Y; Orii, M; Ozaki, Y; Shimamura, K; Shiono, Y; Takarada, S; Tanaka, A; Tanimoto, T; Ueno, S; Yamaguchi, T; Yamano, T | 1 |
| Alpay, MF; Cakir, O; Colak, N; Nazli, Y; Uysal, S; Uzunlar, AK | 1 |
| Abudunaibi, M; Aili, A; Aisikaer, S; Gulibositan, M; Halmurat, U; Mulati, A; Qiao, J; Zulifeiya, M | 1 |
| Abdel-Hamid, AA; Firgany, Ael-D | 1 |
| Akalin Çiftçi, G; Akalin, A; Alataş, İÖ; Ertorun, İ; Musmul, A | 1 |
| Deng, Y; Guo, XL; Liu, HG; Pan, YY; Yuan, X; Zhu, D | 1 |
| Sozer, V | 1 |
| Dormanesh, B; Ghaznavi, H; Hosseini Tabatabaei, SM; Hosseinzadeh, A; Kamrava, SK; Mehrzadi, S; Motevalian, M | 1 |
| Chen, Y; Li, B; Moorhead, JF; Ruan, XZ; Varghese, Z; Wu, W; Yang, P; Zhao, L; Zhou, W | 1 |
| Dehpour, AR; Rayegan, S; Sharifi, AM | 1 |
| Aykol, S; Civi, S; Kardes, O; Omeroglu, S; Oyar, EO; Tufan, K | 1 |
| Chen, WR; Chen, YD; Liu, HB; Sha, Y; Shi, XM; Shi, Y; Wang, H; Yin, DW | 1 |
| Cho, SY; Kim, SW; Kwon, OS; Paick, JS; Park, J | 1 |
| Chatsudthipong, V; Chattipakorn, N; Jaikumkao, K; Lungkaphin, A; Pongchaidecha, A; Thongnak, L | 1 |
| Erdi, I; Kaya, B; Yasar, M | 1 |
| Chuturgoon, AA; Docrat, TF; Krishnan, A; Nagiah, S; Naidoo, DB | 1 |
| Fei, MY; Hu, GP; Liu, ZJ; Shi, QX; Sun, F; Yin, Z | 1 |
| Deng, Y; Guan, X; Kang, J; Li, D; Liu, Q; Liu, Y; Sun, Y; Tao, Z; Wang, X; Xu, H | 1 |
| Bandegi, AR; Dehdashti, A; Ghanbari, A; Goodarzi, Z; Karami, E; Yousefi, S | 1 |
| Abuawad, Z; Andelova, K; Fulop, M; Kalocayova, B; Kura, B; Sagatova, A; Slezak, J; Sykora, M; Szeiffova Bacova, B | 1 |
| Abdel-Razek, HAD; Abdou, AG; Hassan, MHA; Hazzaa, SM; Ibraheim, EO; Salem, EA | 1 |
| El-Sayyad, SM; Ibrahim, SSA; Kandil, LS; Ragab, GM | 1 |
| Elawady, AS; Elnagar, GM; Elseweidy, MM; Sobh, MS | 1 |
| Ghazi-Khansari, M; Jazaeri, F; Mehreen, S; Niaz, Q; Tavangar, SM | 1 |
| Adeyemi, DH; Afolabi, OA; Akhigbe, RE; Anyogu, DC; Hamed, MA; Odetayo, AF | 1 |
| Chen, N; Du, Z; Luo, M; Ma, X; Shu, X; Wang, L; Wu, J; Xu, J; You, J; Zhang, T | 1 |
15 trial(s) available for atorvastatin and malondialdehyde
| Article | Year |
|---|---|
Effects of atorvastatin and pravastatin on malondialdehyde-modified LDL in hypercholesterolemic patients.
Topics: Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol, HDL; Cross-Over Studies; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins, LDL; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Pravastatin; Pyrroles | 2003 |
Short-term effects of low-dose atorvastatin on inflammatory status and lipid profiles in perimenopausal hypercholesterolemic, hypertriglyceridemic women.
Topics: Adult; Atorvastatin; Blood Coagulation; C-Reactive Protein; Cholesterol; Cholesterol, LDL; Female; Fibrinolysis; Gonadal Steroid Hormones; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Inflammation; Lipids; Lipoproteins; Malondialdehyde; Middle Aged; Plasminogen Activator Inhibitor 1; Postmenopause; Premenopause; Prospective Studies; Pyrroles; Time Factors; Tissue Plasminogen Activator; Triglycerides | 2006 |
[Estimation of antioxidative effect of atorvastatin and fluvastatin used in primary prevention of coronary heart disease--effect on lipid peroxidation].
Topics: Adult; Anticholesteremic Agents; Antioxidants; Atorvastatin; Coronary Artery Disease; Fatty Acids, Monounsaturated; Female; Fluvastatin; Free Radical Scavengers; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Primary Prevention; Pyrroles; Treatment Outcome | 2005 |
eNOS gene T-786C polymorphism modulates atorvastatin-induced increase in blood nitrite.
Topics: Adolescent; Adult; Amino Acid Substitution; Atorvastatin; Cyclic GMP; Heptanoic Acids; Humans; Male; Malondialdehyde; Middle Aged; Nitric Oxide Synthase Type III; Nitrites; Polymorphism, Genetic; Pyrroles; Thiobarbiturates | 2006 |
Effect of atorvastatin on type 2 diabetic dyslipidemia.
Topics: Adult; Aged; Apolipoprotein A-I; Apolipoprotein B-100; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Pyrroles; Superoxide Dismutase; Time Factors; Treatment Outcome; Triglycerides | 2006 |
Atorvastatin induces associated reductions in platelet P-selectin, oxidized low-density lipoprotein, and interleukin-6 in patients with coronary artery diseases.
Topics: Aged; Atorvastatin; Blood Platelets; Cholesterol; Combined Modality Therapy; Coronary Artery Disease; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Interleukin-6; Lipoproteins, LDL; Male; Malondialdehyde; Middle Aged; P-Selectin; Pyrroles; Time Factors; Treatment Outcome; Triglycerides | 2008 |
Comparison of effects of simvastatin versus atorvastatin on oxidative stress in patients with coronary heart disease.
Topics: Aged; Analysis of Variance; Atorvastatin; Biomarkers; Chi-Square Distribution; Coronary Disease; Diet, Fat-Restricted; Female; Glutathione; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver Function Tests; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Prospective Studies; Pyrroles; Simvastatin; Superoxide Dismutase; Treatment Outcome | 2010 |
Preoperative atorvastatin treatment in CABG patients rapidly improves vein graft redox state by inhibition of Rac1 and NADPH-oxidase activity.
Topics: Aged; Atherosclerosis; Atorvastatin; Coronary Artery Bypass; Double-Blind Method; Enzyme Activation; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Lipoproteins, LDL; Male; Malondialdehyde; Middle Aged; NADPH Oxidases; Organ Culture Techniques; Oxidation-Reduction; Preoperative Care; Pyrroles; rac1 GTP-Binding Protein; Saphenous Vein; Superoxides | 2010 |
Paraoxonase-1 activity, malondialdehyde and glutathione peroxidase in non-alcoholic fatty liver disease and the effect of atorvastatin.
Topics: Adult; Alanine Transaminase; Anticholesteremic Agents; Aryldialkylphosphatase; Aspartate Aminotransferases; Atorvastatin; Cholesterol; Cross-Sectional Studies; Disease Progression; Fatty Liver; Female; Glutathione Peroxidase; Hepatitis; Heptanoic Acids; Humans; Lipid Peroxidation; Lipoproteins, HDL; Lipoproteins, LDL; Male; Malondialdehyde; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Pyrroles; Risk Factors; Triglycerides | 2011 |
Atorvastatin 10 mg plus ezetimibe 10mg compared with atorvastatin 20 mg: impact on the lipid profile in Japanese patients with abnormal glucose tolerance and coronary artery disease.
Topics: Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Atorvastatin; Azetidines; Cholesterol; Cholesterol, LDL; Coronary Disease; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Ezetimibe; Female; Glucose Intolerance; Heptanoic Acids; Humans; Lipoproteins, LDL; Male; Malondialdehyde; Oxidation-Reduction; Prospective Studies; Pyrroles | 2012 |
Atorvastatin reduces malondialdehyde concentrations in patients with polycystic ovary syndrome.
Topics: Adult; Atorvastatin; Double-Blind Method; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Insulin Resistance; Malondialdehyde; Metformin; Oxidative Stress; Polycystic Ovary Syndrome; Pyrroles; Treatment Outcome | 2012 |
No effect of atorvastatin and simvastatin on oxidative stress in patients at high risk for cardiovascular disease.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Atorvastatin; Cardiovascular Diseases; Cholesterol, LDL; Deoxyguanosine; F2-Isoprostanes; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Peroxidase; Pyrroles; Simvastatin; Ubiquinone | 2013 |
Effect of atorvastatin therapy on fibrous cap thickness in coronary atherosclerotic plaque as assessed by optical coherence tomography: the EASY-FIT study.
Topics: Aged; Atorvastatin; C-Reactive Protein; Cholesterol, LDL; Coronary Artery Disease; Coronary Vessels; Dose-Response Relationship, Drug; Dyslipidemias; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Macrophages; Male; Malondialdehyde; Matrix Metalloproteinase 9; Middle Aged; Plaque, Atherosclerotic; Prospective Studies; Pyrroles; Tomography, Optical Coherence | 2014 |
Effects of Statin on Arrhythmia and Heart Rate Variability in Healthy Persons With 48-Hour Sleep Deprivation.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Atorvastatin; C-Reactive Protein; Double-Blind Method; Electrocardiography; Female; Healthy Volunteers; Heart Rate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Male; Malondialdehyde; Sleep Deprivation; Superoxide Dismutase; Young Adult | 2016 |
Effects of Short-term High Dose Atorvastatin on Left Ventricular Remodeling in Patients with First Time Attack of Anterior Acute Myocardial Infarction.
Topics: Adolescent; Adult; Aged; Atorvastatin; C-Reactive Protein; Drug Administration Schedule; Echocardiography; Endothelin-1; Female; Humans; Male; Malondialdehyde; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Middle Aged; Myocardial Infarction; Ventricular Function, Left; Ventricular Remodeling; Young Adult | 2018 |
45 other study(ies) available for atorvastatin and malondialdehyde
| Article | Year |
|---|---|
The effect of lipoproteins on endothelial nitric oxide synthase is modulated by lipoperoxides.
Topics: Adult; Anticholesteremic Agents; Ascorbic Acid; Atorvastatin; Cells, Cultured; Cholesterol, LDL; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hyperlipoproteinemia Type II; Lipid Peroxidation; Lipid Peroxides; Lipids; Lipoproteins, LDL; Male; Malondialdehyde; Middle Aged; Nitrates; Nitric Oxide Synthase; Nitrites; Pyrroles | 2003 |
[Effects of atorvastatin, fluvastatin, pravastatin, and simvastatin on endothelial function, lipid peroxidation, and aortic atherosclerosis in hypercholesterolemic rabbits].
Topics: Animals; Anticholesteremic Agents; Aortic Diseases; Arteriosclerosis; Atorvastatin; Cholesterol; Cholesterol, LDL; Endothelium, Vascular; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Hypercholesterolemia; Indoles; Lipid Peroxidation; Male; Malondialdehyde; Pravastatin; Pyrroles; Rabbits; Simvastatin | 2005 |
Attenuation of contractile dysfunction by atorvastatin after intestinal ischemia reperfusion injury in rats.
Topics: Administration, Oral; Animals; Atorvastatin; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Glutathione; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ileum; In Vitro Techniques; Intestines; Male; Malondialdehyde; Muscle Contraction; Neurotransmitter Agents; Peroxidase; Potassium Chloride; Pyrroles; Rats; Rats, Wistar; Reperfusion Injury; Substance P | 2007 |
Atorvastatin downregulates BMP-2 expression induced by oxidized low-density lipoprotein in human umbilical vein endothelial cells.
Topics: Antioxidants; Atorvastatin; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Nucleus; Cells, Cultured; Cytoplasm; Down-Regulation; Drug Interactions; Endothelial Cells; Gene Expression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Malondialdehyde; Proline; Pyrroles; RNA, Messenger; Superoxide Dismutase; Thiocarbamates; Transcription Factor RelA; Transforming Growth Factor beta; Umbilical Veins | 2008 |
Relationship between biomarkers of oxidized low-density lipoprotein, statin therapy, quantitative coronary angiography, and atheroma: volume observations from the REVERSAL (Reversal of Atherosclerosis with Aggressive Lipid Lowering) study.
Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins B; Atherosclerosis; Atorvastatin; Autoantibodies; Biomarkers; Cholesterol, LDL; Coronary Angiography; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulin G; Immunoglobulin M; Lipoprotein(a); Male; Malondialdehyde; Middle Aged; Oxidative Stress; Phospholipids; Pravastatin; Prospective Studies; Pyrroles; Research Design | 2008 |
Anti-atherogenic effect of statins: role of nitric oxide, peroxynitrite and haem oxygenase-1.
Topics: Animals; Aorta; Arginine; Atherosclerosis; Atorvastatin; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Heme Oxygenase-1; Hemin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Male; Malondialdehyde; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Protoporphyrins; Pyrroles; Rabbits; Simvastatin; Time Factors | 2009 |
Eugenosedin-A prevents hyperglycaemia, hyperlipidaemia and lipid peroxidation in C57BL/6J mice fed a high-fat diet.
Topics: Adipose Tissue; Animals; Atorvastatin; Blood Glucose; Body Weight; Brain; Dietary Fats; Female; Glutathione Peroxidase; Heptanoic Acids; Hyperglycemia; Hyperlipidemias; Insulin; Ketanserin; Lipid Peroxidation; Lipogenesis; Liver; Malondialdehyde; Mice; Mice, Inbred C57BL; Piperazines; PPAR gamma; Prazosin; Propranolol; Pyrroles; Superoxide Dismutase; Weight Gain | 2009 |
Atorvastatin prevents endothelial dysfunction in mesenteric arteries from spontaneously hypertensive rats: role of cyclooxygenase 2-derived contracting prostanoids.
Topics: Analysis of Variance; Animals; Atorvastatin; Blotting, Western; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelium, Vascular; Heptanoic Acids; Male; Malondialdehyde; Mesenteric Arteries; Probability; Prostaglandins; Pyrroles; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sensitivity and Specificity; Vasodilation | 2009 |
Effects of atorvastatin therapy on protein oxidation and oxidative DNA damage in hypercholesterolemic rabbits.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticholesteremic Agents; Atorvastatin; Deoxyguanosine; DNA Damage; Glutathione; Heptanoic Acids; Hypercholesterolemia; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Pyrroles; Rabbits; Random Allocation; Sulfhydryl Compounds | 2009 |
Atorvastatin prevents angiotensin II-induced vascular remodeling and oxidative stress.
Topics: Angiotensin II; Animals; Atorvastatin; Blood Pressure; Blotting, Western; Cells, Cultured; Collagen; Elasticity; Extracellular Matrix; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Malondialdehyde; Mesenteric Arteries; Microscopy, Confocal; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type III; Oxidative Stress; Pyrroles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Superoxide Dismutase; Superoxides; Vasoconstrictor Agents | 2009 |
Effect of atorvastatin and ezetimibe treatment on serum lipid profile and oxidative state in rats fed with a high-cholesterol diet.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Azetidines; Catalase; Cholesterol, Dietary; Ezetimibe; Glutathione Peroxidase; Heptanoic Acids; Lipid Metabolism; Lipid Peroxidation; Lipids; Malondialdehyde; Pyrroles; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2010 |
Effect of combined administration of ginger (Zingiber officinale Roscoe) and atorvastatin on the liver of rats.
Topics: Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Antioxidants; Atorvastatin; Catalase; Chemical and Drug Induced Liver Injury; Cholesterol; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Heptanoic Acids; Liver; Male; Malondialdehyde; Nitric Oxide; Phytotherapy; Plant Extracts; Pyrroles; Random Allocation; Rats; Rats, Wistar; Rhizome; Superoxide Dismutase; Transaminases; Vitamin E; Zingiber officinale | 2010 |
Effects of atorvastatin on fine particle-induced inflammatory response, oxidative stress and endothelial function in human umbilical vein endothelial cells.
Topics: Air Pollutants; Anti-Inflammatory Agents; Atorvastatin; Cell Survival; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Heptanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Malondialdehyde; Nitric Oxide; Oxidative Stress; P-Selectin; Particulate Matter; Pyrroles; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2011 |
[A dyslipidemia animal model induced by poloxamer 407 in golden hamsters and pilot study on the mechanism].
Topics: Animals; Anticholesteremic Agents; Atorvastatin; CD36 Antigens; Cricetinae; Disease Models, Animal; Dyslipidemias; Fenofibrate; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lipid Metabolism; Liver; Male; Malondialdehyde; Mesocricetus; Nitric Oxide; Phosphatidylcholine-Sterol O-Acyltransferase; Poloxamer; PPAR alpha; Pyrroles; RNA, Messenger; Superoxide Dismutase | 2011 |
Neuroprotective potential of atorvastatin and simvastatin (HMG-CoA reductase inhibitors) against 6-hydroxydopamine (6-OHDA) induced Parkinson-like symptoms.
Topics: Amphetamine; Analysis of Variance; Animals; Atorvastatin; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Glutathione; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Male; Malondialdehyde; Mitochondria; Motor Activity; NADH Dehydrogenase; Nitrites; Oxidopamine; Parkinsonian Disorders; Pyrroles; Rats; Rats, Wistar; Simvastatin; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2012 |
The effect of atorvastatin and simvastatin on vitamin D, oxidative stress and inflammatory marker concentrations in patients with type 2 diabetes: a crossover study.
Topics: Atorvastatin; Biomarkers; C-Reactive Protein; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lipids; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Pyrroles; Simvastatin; Treatment Outcome; Vitamin D | 2013 |
Protective role of atorvastatin against doxorubicin-induced cardiotoxicity and testicular toxicity in mice.
Topics: Animals; Antioxidants; Atorvastatin; Cardiomyopathies; Comet Assay; DNA Fragmentation; Doxorubicin; Glutathione; Heart; Heptanoic Acids; Lipid Peroxidation; Male; Malondialdehyde; Mice; Micronucleus Tests; Oxidative Stress; Pyrroles; Testicular Diseases; Testis | 2013 |
Effects of atorvastatin on the hypertension-induced oxidative stress in the rat brain.
Topics: Animals; Atorvastatin; Blood Pressure; Brain; Cardiomegaly; Catalase; Glutathione; Heptanoic Acids; Hypertension; Male; Malondialdehyde; Oxidative Stress; Pyrroles; Rats; Rats, Wistar; Superoxide Dismutase | 2013 |
Atorvastatin reduces the myocardial content of coenzyme Q10 in isoproterenol-induced heart failure in rats.
Topics: Animals; Antioxidants; Atorvastatin; Heart Failure; Heptanoic Acids; Isoproterenol; Lipid Peroxidation; Lipids; Male; Malondialdehyde; Myocardium; Pyrroles; Rats; Rats, Wistar; Ubiquinone | 2014 |
Atorvastatin attenuates bleomycin-induced pulmonary fibrosis via suppressing iNOS expression and the CTGF (CCN2)/ERK signaling pathway.
Topics: Animals; Atorvastatin; Bleomycin; Body Weight; Collagen; Connective Tissue Growth Factor; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Pulmonary Fibrosis; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction | 2013 |
Prevention of arterial stiffening by using low-dose atorvastatin in diabetes is associated with decreased malondialdehyde.
Topics: Animals; Arginine; Atorvastatin; Blood Glucose; Blood Pressure; Body Weight; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fatty Acids; Glycation End Products, Advanced; Hemodynamics; Heptanoic Acids; Lysine; Male; Malondialdehyde; Organ Size; Pyrroles; Rats, Wistar; Streptozocin; Vascular Stiffness | 2014 |
Atorvastatin attenuates the paraquat-induced pulmonary inflammation via PPARγ receptors: a new indication for atorvastatin.
Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Heptanoic Acids; Herbicides; Interleukin-6; Lung; Male; Malondialdehyde; Nitric Oxide; Paraquat; Peroxidase; Pioglitazone; Pneumonia; PPAR gamma; Pyrroles; Rats, Wistar; Thiazolidinediones; Tumor Necrosis Factor-alpha; Weight Loss | 2014 |
Neuroprotective effect of atorvastatin in spinal cord ischemia-reperfusion injury.
Topics: Animals; Atorvastatin; Biopsy; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Malondialdehyde; Neuroprotective Agents; Nitric Oxide; Paraplegia; Pyrroles; Rabbits; Random Allocation; Reperfusion Injury; Reproducibility of Results; Spinal Cord Ischemia; Superoxide Dismutase; Time Factors | 2015 |
Myocardial protective effects of Munziq in myocardial ischemia-reperfusion injury rats with abnormal savda syndrome.
Topics: Animals; Arterial Pressure; Atorvastatin; Cardiotonic Agents; Drug Evaluation, Preclinical; Female; HSP70 Heat-Shock Proteins; Interleukin-6; Interleukin-8; Male; Malondialdehyde; Myocardial Reperfusion Injury; Plant Extracts; Rats, Wistar; Superoxide Dismutase | 2015 |
Atorvastatin alleviates experimental diabetic cardiomyopathy by suppressing apoptosis and oxidative stress.
Topics: Animals; Apoptosis; Atorvastatin; Biomarkers; Blood Glucose; Caspase 3; Diabetic Cardiomyopathies; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Malondialdehyde; Myocardium; Myocytes, Cardiac; Oxidation-Reduction; Oxidative Stress; Rats | 2015 |
The effects of atorvastatin on antioxidant/antiinflammatory properties of HDLs in hypercholesterolemics.
Topics: Adult; Anticholesteremic Agents; Arginine; Atorvastatin; Drug Monitoring; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Inflammation; Lipoproteins, HDL; Male; Malondialdehyde; Middle Aged; Nitric Oxide; Oxidative Stress; Pyrroles; Treatment Outcome | 2015 |
Efficacy of atorvastatin on hippocampal neuronal damage caused by chronic intermittent hypoxia: Involving TLR4 and its downstream signaling pathway.
Topics: Animals; Atorvastatin; Chronic Disease; Disease Models, Animal; Hippocampus; Hypoxia; Interleukin-1beta; Male; Malondialdehyde; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Neurons; Neuroprotective Agents; Random Allocation; Signal Transduction; Sleep Apnea, Obstructive; Superoxide Dismutase; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2015 |
Ameliorative effect of statin therapy on oxidative damage in heart tissue of hypercholesterolemic rabbits.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Aryldialkylphosphatase; Atherosclerosis; Atorvastatin; Cholesterol, LDL; Diet; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Malondialdehyde; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Rabbits; Superoxide Dismutase | 2015 |
Melatonin synergistically enhances protective effect of atorvastatin against gentamicin-induced nephrotoxicity in rat kidney.
Topics: Acute Kidney Injury; Animals; Atorvastatin; Creatinine; Drug Synergism; Gentamicins; Glutathione; Kidney; Kidney Function Tests; Male; Malondialdehyde; Melatonin; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Urea | 2016 |
Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice.
Topics: Animals; Apolipoproteins E; Atorvastatin; Caseins; Catalase; Chemical and Drug Induced Liver Injury; Gene Expression Regulation; Inflammation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase | 2016 |
Studying neuroprotective effect of Atorvastatin as a small molecule drug on high glucose-induced neurotoxicity in undifferentiated PC12 cells: role of NADPH oxidase.
Topics: Animals; Atorvastatin; Cell Survival; Glucose; Lipid Peroxidation; Malondialdehyde; NADPH Oxidases; Neurons; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species | 2017 |
Effects of Atorvastatin on Experimental Spinal Cord Ischemia-Reperfusion Injury in Rabbits.
Topics: Animals; Atorvastatin; Biomarkers; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Malondialdehyde; Neuroprotective Agents; Nitric Oxide; Rabbits; Reperfusion Injury; Secondary Prevention; Spinal Cord; Spinal Cord Injuries; Spinal Cord Ischemia | 2017 |
Chronic administration of atorvastatin could partially ameliorate erectile function in streptozotocin-induced diabetic rats.
Topics: Administration, Intravenous; Animals; Arterial Pressure; Atorvastatin; Diabetes Mellitus, Experimental; Erectile Dysfunction; Male; Malondialdehyde; Penile Erection; Pyrimidines; Rats; Rats, Sprague-Dawley; Sulfonamides; Superoxide Dismutase | 2017 |
The additive effects of atorvastatin and insulin on renal function and renal organic anion transporter 3 function in diabetic rats.
Topics: Animals; Atorvastatin; Diabetes Mellitus, Experimental; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Interleukin-6; Kidney; Male; Malondialdehyde; Organic Anion Transporters, Sodium-Independent; Oxidative Stress; Pancreas; Protein Kinase C-alpha; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Superoxide Dismutase | 2017 |
The preventive effects of atorvastatin and N-acetyl cysteine in experimentally induced ischemia-reperfusion injury in rats.
Topics: Acetylcysteine; Animals; Atorvastatin; Catalase; Cecal Diseases; Cecum; Disease Models, Animal; Female; Free Radical Scavengers; Glutathione Peroxidase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intestinal Volvulus; Male; Malondialdehyde; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase | 2018 |
Atorvastatin induces MicroRNA-145 expression in HEPG2 cells via regulation of the PI3K/AKT signalling pathway.
Topics: Antineoplastic Agents; Apoptosis; Atorvastatin; Caspases; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Glycogen Synthase Kinase 3 beta; Hep G2 Cells; Humans; Malondialdehyde; MicroRNAs; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Up-Regulation | 2018 |
Atorvastatin inhibits renal inflammatory response induced by calcium oxalate crystals via inhibiting the activation of TLR4/NF-κB and NLRP3 inflammasome.
Topics: Animals; Antioxidants; Atorvastatin; Blood Urea Nitrogen; Caspase 1; Creatinine; Gene Expression Regulation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammasomes; Interleukin-1beta; Interleukin-6; Kidney; L-Lactate Dehydrogenase; Male; Malondialdehyde; Nephrolithiasis; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Toll-Like Receptor 4 | 2020 |
Hepatoprotective effect of atorvastatin on Cadmium chloride induced hepatotoxicity in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Atorvastatin; Cadmium; Cadmium Chloride; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2020 |
The effect of selected drugs on the mitigation of myocardial injury caused by gamma radiation.
Topics: Animals; Atorvastatin; Cardiomyopathies; Free Radicals; Gamma Rays; Heart; Male; Malondialdehyde; Myocardium; Oxidative Stress; Radiation Injuries, Experimental; Rats; Tadalafil; Treatment Outcome; Tumor Necrosis Factor-alpha | 2021 |
Effect of L-carnitine and atorvastatin on a rat model of ischemia-reperfusion injury of spinal cord.
Topics: Advanced Oxidation Protein Products; Animals; Atorvastatin; bcl-2-Associated X Protein; Carnitine; Catalase; Malondialdehyde; Nitrates; Nitrites; Rats; Reactive Oxygen Species; Reperfusion Injury; Spinal Cord; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2021 |
Micro RNAs 26b, 20a inversely correlate with GSK-3 β/NF-κB/NLRP-3 pathway to highlight the additive promising effects of atorvastatin and quercetin in experimental induced arthritis.
Topics: Alanine Transaminase; Animals; Antirheumatic Agents; Arthritis, Experimental; Aspartate Aminotransferases; Atorvastatin; CARD Signaling Adaptor Proteins; Carrier Proteins; Caspase 1; Cell Cycle Proteins; Correlation of Data; Cytokines; Glycogen Synthase Kinase 3 beta; I-kappa B Proteins; Male; Malondialdehyde; Methotrexate; MicroRNAs; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Quercetin; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Lycopene ameliorates hyperlipidemia via potentiation of AMP-activated protein kinase and inhibition of ATP-citrate lyase in diabetic hyperlipidemic rat model.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Atorvastatin; ATP Citrate (pro-S)-Lyase; Biomarkers; Coenzyme A; Diabetes Mellitus; Fatty Acid Synthases; Glutathione; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Lycopene; Malondialdehyde; Multienzyme Complexes; Oxo-Acid-Lyases; Rats; Streptozocin; Tumor Necrosis Factor-alpha | 2022 |
Evaluation of statins as a new therapy to alleviate chronotropic dysfunction in cirrhotic rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Atorvastatin; Cholesterol; Fibrosis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ligation; Liver; Liver Cirrhosis; Male; Malondialdehyde; Natriuretic Peptides; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; rhoA GTP-Binding Protein; Tumor Necrosis Factor-alpha | 2022 |
Atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion injury.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Apoptosis; Atorvastatin; Caspase 3; Down-Regulation; Female; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Ischemia; Malondialdehyde; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Tumor Necrosis Factor-alpha; Uric Acid; Vascular Cell Adhesion Molecule-1; Xanthine Oxidase | 2022 |
Statin-Induced Geranylgeranyl Pyrophosphate Depletion Promotes Ferroptosis-Related Senescence in Adipose Tissue.
Topics: Adipose Tissue; Animals; Atorvastatin; beta-Galactosidase; Ferroptosis; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iron; Malondialdehyde; Mice; Phospholipid Hydroperoxide Glutathione Peroxidase; Reactive Oxygen Species; RNA, Messenger | 2022 |