atorvastatin has been researched along with indomethacin in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 10 (71.43) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Beaumont, K; Di, L; Maurer, TS; Smith, DA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gardiner, P; Paine, SW; Parker, AJ; Riley, RJ; Webborn, PJ | 1 |
| Kathirvel, K; Kuntamallappanavar, G; Leo, MD; Mishra, SK; Subramani, J; Uttam Singh, T | 1 |
| Buerke, M; Chen, L; Frister, A; Hofmann, B; Lautenschläger, M; Loppnow, H; Luther, T; Müller-Werdan, U; Rose-John, S; Schlitt, A; Silber, RE; Song, N; Werdan, K; Zhang, L | 1 |
| Atukeren, P; Gümüştaş, K; Gürel, A; Özdemir, O; Özyoğurtçu, H; Uyanik, Ö; Uydeş-Doğan, S; Yildirim, FI | 1 |
| Botelho, T; de Batista, PR; Padilha, AS; Ribeiro-Júnior, RF; Simões, FV; Vassallo, DV | 1 |
| Al-Hiari, Y; Al-Qirim, T; Alalawi, S; Arabiyat, S; Haj Hussein, B; Ikhmais, B; Kasabri, V | 1 |
1 review(s) available for atorvastatin and indomethacin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for atorvastatin and indomethacin
| Article | Year |
|---|---|
Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures.
Topics: Aspirin; Atorvastatin; Cell Separation; Coculture Techniques; Dose-Response Relationship, Drug; Drug Synergism; Heptanoic Acids; HMGB1 Protein; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indomethacin; Interleukin-1; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Pyrroles; Recombinant Proteins; Simvastatin; STAT3 Transcription Factor; Time Factors; Tumor Necrosis Factor-alpha | 2011 |
12 other study(ies) available for atorvastatin and indomethacin
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Volume of Distribution in Drug Design.
Topics: Drug Design; Half-Life; Pharmacokinetics | 2015 |
Prediction of the pharmacokinetics of atorvastatin, cerivastatin, and indomethacin using kinetic models applied to isolated rat hepatocytes.
Topics: Animals; Atorvastatin; Hepatocytes; Heptanoic Acids; Indomethacin; Male; Models, Biological; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley | 2008 |
Atorvastatin restores the impaired vascular endothelium-dependent relaxations mediated by nitric oxide and endothelium-derived hyperpolarizing factors but not hypotension in sepsis.
Topics: Acetylcholine; Animals; Aorta; Atorvastatin; Biological Factors; Blood Cell Count; Blood Pressure; Calcium Channel Blockers; Cytochrome P-450 Enzyme Inhibitors; Disease Models, Animal; Endothelium, Vascular; Gene Expression; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypotension; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Nitroprusside; Phenylephrine; Pulmonary Artery; Pyrroles; Rats; Rats, Wistar; Sepsis; Vasodilation | 2009 |
Aggravating effect of atorvastatin on indomethacin-induced gastric injury: Focus on PGE2, TNF-α, neutrophils and iNOS.
Topics: Amidines; Animals; Atorvastatin; Benzylamines; Dinoprostone; Drug Synergism; Female; Indomethacin; Male; Mevalonic Acid; Neutrophil Infiltration; Neutrophils; Nitric Oxide Synthase Type II; Rats; Stomach Ulcer; Tumor Necrosis Factor-alpha | 2015 |
Treatment with high dose of atorvastatin reduces vascular injury in diabetic rats.
Topics: Animals; Aorta; Atorvastatin; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Endothelium, Vascular; Indomethacin; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitrobenzenes; Phenylephrine; Prostaglandins; Rats; Rats, Wistar; Streptozocin; Sulfonamides; Superoxides; Vascular System Injuries; Vasodilation; Vasodilator Agents | 2016 |
Selected Statins as Dual Antiproliferative-Antiinflammatory Compounds.
Topics: Anti-Inflammatory Agents; Atorvastatin; Caco-2 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indomethacin; Pancreatic Neoplasms | 2022 |