Page last updated: 2024-08-24

atorvastatin and homocysteine

atorvastatin has been researched along with homocysteine in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (44.83)29.6817
2010's13 (44.83)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
Bruckert, E; Chapman, MJ; Foglietti, MJ; Giral, P; Jacob, N; Turpin, G1
Atwal, AS; Davis, M; Hamilton, G; Jagroop, IA; Mikhailidis, DP; Nair, DR; Seifalian, AM1
Elisaf, M; Kakafika, A; Tsimihodimos, V1
Azuma, A; Harada, S; Kunitomo, K; Kuwahara, N; Nakagawa, M; Sasaki, S; Takeda, K; Yamada, T1
Chasiotis, G; Elisaf, M; Miltiadous, G; Papakostas, J; Seferiadis, K1
Chasiotis, G; Elisaf, MS; Kakafika, A; Milionis, HJ; Papakostas, J; Seferiadis, K1
García-Idoate, G; Mora, C; Muros, M; Navarro, JF1
Shah, DI; Singh, M1
Bolaman, Z; Kadikoylu, G; Ozgel, N; Yenisey, C1
Altug, T; Aslan, M; Balci, H; Bolayirli, IM; Hacibekiroglu, M; Seven, A1
Berker, B; Cengiz, SD; Cesur, M; Demirtaş, S; Erdoğan, G; Kaya, C1
Boroumand, MA; Djalali, M; Eshragian, MR; Khatami, MR; Shojaei, MH; Siassi, F1
Bao, XM; Lu, GP; Wu, CF3
Chen, Z; Jia, F; Lu, G; Wu, C2
Koppensteiner, R; Spring, S; van der Loo, B1
Bao, XM; Zheng, H1
Gilowski, W; Krysiak, R; Okopien, B; Szkrobka, W1
Broncel, M; Chwatko, G; Jackowska, P; Koter-Michalak, M; Kubalczyk, P; Olszewska-Banaszczyk, M; Pytel, E1
Chen, Z; Jia, F; Lu, G; Sun, J; Wu, C1
Al-Muzafar, HM; Amin, KA1
Bolevich, S; Jakovljevic, V; Joksimovic, J; Katanic, J; Mihailovic, V; Mijailovic, N; Nikolic, T; Pantic, M; Rosic, G; Selakovic, D; Zivkovic, V1
Krysiak, R; Okopień, B; Szkróbka, W2
Bednarska-Czerwińska, A; Kowalcze, K; Krysiak, R; Okopień, B1
Kowalcze, K; Krysiak, R; Okopień, B1
Bottiglieri, T; Fardo, DW; Johnson, SN; Qiao, Q; Rogers, CB; Sudduth, TL; Weekman, EM; Wilcock, DM; Xie, K1

Trials

8 trial(s) available for atorvastatin and homocysteine

ArticleYear
Homocysteine and lipid lowering agents. A comparison between atorvastatin and fenofibrate in patients with mixed hyperlipidemia.
    Atherosclerosis, 2001, Feb-01, Volume: 154, Issue:2

    Topics: Atorvastatin; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Female; Fenofibrate; Heptanoic Acids; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type V; Hypolipidemic Agents; Male; Middle Aged; Pyrroles; Triglycerides

2001
The effect of short-term lipid lowering with atorvastatin on carotid artery intima media thickness in patients with peripheral vascular disease: a pilot study.
    Current medical research and opinion, 2000, Volume: 16, Issue:3

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Carotid Arteries; Cholesterol; Exercise Test; Female; Fibrinogen; Heptanoic Acids; Homocysteine; Humans; Male; Middle Aged; Peripheral Vascular Diseases; Pilot Projects; Pyrroles; Statistics, Nonparametric; Tunica Intima; Tunica Media; Ultrasonography

2000
Comparative effects of atorvastatin, simvastatin, and fenofibrate on serum homocysteine levels in patients with primary hyperlipidemia.
    Journal of clinical pharmacology, 2003, Volume: 43, Issue:8

    Topics: Analysis of Variance; Atorvastatin; Blood Glucose; Female; Fenofibrate; Heptanoic Acids; Homocysteine; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Pyrroles; Simvastatin; Uric Acid

2003
Comparative effects of atorvastatin and simvastatin on the plasma total homocysteine levels in women with polycystic ovary syndrome: a prospective randomized study.
    Fertility and sterility, 2009, Volume: 92, Issue:2

    Topics: Adult; Anticholesteremic Agents; Atorvastatin; Female; Heptanoic Acids; Homocysteine; Humans; Hyperhomocysteinemia; Metabolic Clearance Rate; Polycystic Ovary Syndrome; Pyrroles; Retrospective Studies; Simvastatin; Treatment Outcome

2009
High-dose atorvastatin treatment in patients with peripheral arterial disease: effects on platelet aggregation, blood rheology and plasma homocysteine.
    Clinical hemorheology and microcirculation, 2011, Volume: 47, Issue:4

    Topics: Aged; Atorvastatin; Female; Hemorheology; Heptanoic Acids; Homocysteine; Humans; Male; Middle Aged; Peripheral Arterial Disease; Platelet Aggregation; Prospective Studies; Pyrroles

2011
The Effect of Atorvastatin on Cardiometabolic Risk Factors in Bromocriptine-Treated Premenopausal Women with Isolated Hypercholesterolemia.
    Cardiovascular therapeutics, 2015, Volume: 33, Issue:5

    Topics: Adult; Atorvastatin; Bromocriptine; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diet; Dopamine Agonists; Exercise; Female; Fibrinogen; Homocysteine; Humans; Hypercholesterolemia; Hyperprolactinemia; Hypoglycemic Agents; Hypolipidemic Agents; Metformin; Middle Aged; Premenopause; Risk Factors; Uric Acid

2015
Intensive statin therapy, used alone or in combination with ezetimibe, improves homocysteine level and lipid peroxidation to a similar degree in patients with coronary artery diseases.
    Pharmacological reports : PR, 2016, Volume: 68, Issue:2

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Case-Control Studies; Cholesterol, LDL; Coronary Artery Disease; Drug Therapy, Combination; Ezetimibe; Female; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Male; Middle Aged; Rosuvastatin Calcium

2016
Different Effects of Atorvastatin on Cardiometabolic Risk Factors in Young Women With and Without Hyperprolactinemia.
    Journal of clinical pharmacology, 2019, Volume: 59, Issue:1

    Topics: Adult; Atorvastatin; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Female; Fibrinogen; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperprolactinemia; Lipids; Metabolic Diseases; Middle Aged; Prolactin; Risk Factors

2019

Other Studies

21 other study(ies) available for atorvastatin and homocysteine

ArticleYear
Effect of atorvastatin on serum uric acid levels.
    Atherosclerosis, 2001, Volume: 158, Issue:1

    Topics: Anticholesteremic Agents; Atorvastatin; Heptanoic Acids; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Middle Aged; Pyrroles; Uric Acid

2001
Effects of atorvastatin on oxidized low-density lipoprotein, low-density lipoprotein subfraction distribution, and remnant lipoprotein in patients with mixed hyperlipoproteinemia.
    The American journal of cardiology, 2002, Feb-15, Volume: 89, Issue:4

    Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Electrophoresis, Polyacrylamide Gel; Heptanoic Acids; Homocysteine; Humans; Hyperlipoproteinemias; Lipoprotein(a); Middle Aged; Pyrroles; Triglycerides

2002
Statins and homocysteine.
    Atherosclerosis, 2003, Volume: 166, Issue:1

    Topics: Atorvastatin; Heptanoic Acids; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Pyrroles; Risk Factors; Simvastatin

2003
Effects of atorvastatin on lipid profile and non-traditional cardiovascular risk factors in diabetic patients on hemodialysis.
    Nephron. Clinical practice, 2003, Volume: 95, Issue:4

    Topics: Adult; Aged; Atorvastatin; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Heptanoic Acids; Homocysteine; Humans; Hypercholesterolemia; Kidney Failure, Chronic; Lipid Metabolism; Lipids; Lipoproteins, LDL; Male; Middle Aged; Oxidative Stress; Prospective Studies; Pyrroles; Renal Dialysis; Risk Factors

2003
Involvement of Rho-kinase in experimental vascular endothelial dysfunction.
    Molecular and cellular biochemistry, 2006, Volume: 283, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Antibiotics, Antineoplastic; Aorta, Thoracic; Atorvastatin; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Endothelium, Vascular; Heptanoic Acids; Homocysteine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Intracellular Signaling Peptides and Proteins; Male; Nitrates; Nitrites; Oxidative Stress; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrroles; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Streptozocin; Thiobarbituric Acid Reactive Substances; Vasodilation

2006
Effects of atorvastatin on coagulation parameters and homocysteine in patients with primary hypercholesterolemia.
    Journal of the National Medical Association, 2006, Volume: 98, Issue:8

    Topics: Adult; Aged; Atorvastatin; Biomarkers; Blood Coagulation; Coronary Disease; Female; Fibrinogen; Follow-Up Studies; Heptanoic Acids; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Prospective Studies; Pyrroles; Treatment Outcome

2006
Effects of atorvastatin therapy on hypercholesterolemic rabbits with respect to oxidative stress, nitric oxide pathway and homocysteine.
    Life sciences, 2007, Jun-20, Volume: 81, Issue:2

    Topics: Animals; Arginine; Aryldialkylphosphatase; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Diet; Heptanoic Acids; Homocysteine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipid Peroxidation; Male; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Pyrroles; Rabbits; Thiobarbituric Acid Reactive Substances; Triglycerides

2007
Serum levels of lipoprotein(a) and homocysteine in patients on hemodialysis who take hydroxymethylglutaryl-CoA reductase inhibitors, vitamin B6, and folic acid.
    Iranian journal of kidney diseases, 2009, Volume: 3, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Atorvastatin; Cardiovascular Diseases; Cross-Sectional Studies; Eating; Female; Folic Acid; Heptanoic Acids; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Lipoprotein(a); Lovastatin; Male; Middle Aged; Pyrroles; Renal Dialysis; Risk Factors; Vitamin B 6; Vitamin B Complex; Young Adult

2009
Atorvastatin attenuates homocysteine-induced apoptosis in human umbilical vein endothelial cells via inhibiting NADPH oxidase-related oxidative stress-triggered p38MAPK signaling.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:10

    Topics: Apoptosis; Atorvastatin; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Heptanoic Acids; Homocysteine; Humans; Imidazoles; NADPH Oxidases; Onium Compounds; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Pyrroles; Reactive Oxygen Species; Signal Transduction; Time Factors; Umbilical Veins

2009
Atorvastatin inhibits homocysteine-induced oxidative stress and apoptosis in endothelial progenitor cells involving Nox4 and p38MAPK.
    Atherosclerosis, 2010, Volume: 210, Issue:1

    Topics: Apoptosis; Atorvastatin; Cells, Cultured; Endothelial Cells; Enzyme Activation; Heptanoic Acids; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; NADPH Oxidase 4; NADPH Oxidases; Onium Compounds; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyrroles; Reactive Oxygen Species; Stem Cells

2010
Atorvastatin inhibits homocysteine-induced dysfunction and apoptosis in endothelial progenitor cells.
    Acta pharmacologica Sinica, 2010, Volume: 31, Issue:4

    Topics: Animals; Apoptosis; Atorvastatin; Caspase 3; Cells, Cultured; Endothelial Cells; Gene Expression Regulation; Heptanoic Acids; Homocysteine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; p38 Mitogen-Activated Protein Kinases; Pyrroles; Reactive Oxygen Species; RNA, Messenger; Stem Cells

2010
AMP-activated protein kinase inhibits homocysteine-induced dysfunction and apoptosis in endothelial progenitor cells.
    Cardiovascular drugs and therapy, 2011, Volume: 25, Issue:1

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Apoptosis; Atorvastatin; Cell Movement; Cell Proliferation; Cells, Cultured; Down-Regulation; Endothelial Cells; Heptanoic Acids; Homocysteine; Humans; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Pyrroles; Reactive Oxygen Species; Ribonucleotides; Stem Cells; Up-Regulation

2011
Atorvastatin inhibits homocysteine-induced endoplasmic reticulum stress through activation of AMP-activated protein kinase.
    Cardiovascular therapeutics, 2012, Volume: 30, Issue:6

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Anticholesteremic Agents; Atherosclerosis; Atorvastatin; Blotting, Western; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Heptanoic Acids; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Lipids; Mice; Polymerase Chain Reaction; Pyrroles; Ribonucleotides; Time Factors

2012
Atorvastatin attenuates homocysteine-induced migration of smooth muscle cells through mevalonate pathway involving reactive oxygen species and p38 MAPK.
    Clinical and experimental pharmacology & physiology, 2015, Volume: 42, Issue:8

    Topics: Animals; Atorvastatin; Cell Movement; Dose-Response Relationship, Drug; Homocysteine; MAP Kinase Signaling System; Mevalonic Acid; Myocytes, Smooth Muscle; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2015
Atorvastatin attenuates atherosclerotic plaque destabilization by inhibiting endoplasmic reticulum stress in hyperhomocysteinemic mice.
    Molecular medicine reports, 2016, Volume: 13, Issue:4

    Topics: Animals; Aorta; Apolipoproteins E; Atorvastatin; Blotting, Western; Down-Regulation; Endoplasmic Reticulum Stress; Homocysteine; Hyperhomocysteinemia; Macrophages; Male; Matrix Metalloproteinase 9; Methionine; Mice; Mice, Knockout; Plaque, Atherosclerotic; RAW 264.7 Cells; Real-Time Polymerase Chain Reaction; Thapsigargin; Tumor Necrosis Factor-alpha

2016
Efficacy of functional foods mixture in improving hypercholesterolemia, inflammatory and endothelial dysfunction biomarkers-induced by high cholesterol diet.
    Lipids in health and disease, 2017, Oct-06, Volume: 16, Issue:1

    Topics: Animals; Atorvastatin; Cholesterol; Creatine Kinase; Diet, High-Fat; Dietary Fats; Drug Administration Schedule; Functional Food; Homocysteine; Hypercholesterolemia; L-Lactate Dehydrogenase; Male; Nitric Oxide Synthase Type III; Rats; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2017
The anxiolytic effects of atorvastatin and simvastatin on dietary-induced increase in homocysteine levels in rats.
    Molecular and cellular biochemistry, 2019, Volume: 452, Issue:1-2

    Topics: Animals; Anti-Anxiety Agents; Anticholesteremic Agents; Anxiety Disorders; Atorvastatin; Behavior, Animal; Diet; Homocysteine; Hyperhomocysteinemia; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Simvastatin

2019
The effect of atorvastatin on cardiometabolic risk factors in women with non-classic congenital adrenal hyperplasia: A pilot study.
    Pharmacological reports : PR, 2019, Volume: 71, Issue:3

    Topics: Adrenal Hyperplasia, Congenital; Adult; Androgens; Atorvastatin; C-Reactive Protein; Cardiovascular Diseases; Dehydroepiandrosterone Sulfate; Female; Fibrinogen; Homocysteine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Pilot Projects; Risk Factors; Testosterone; Uric Acid; Vitamin D

2019
The impact of atorvastatin on cardiometabolic risk factors in brothers of women with polycystic ovary syndrome.
    Pharmacological reports : PR, 2021, Volume: 73, Issue:1

    Topics: Adult; Aged; Androgens; Anticholesteremic Agents; Atorvastatin; Blood Glucose; C-Reactive Protein; Cardiometabolic Risk Factors; Female; Fibrinogen; Homocysteine; Humans; Hydroxycholecalciferols; Insulin Resistance; Lipids; Male; Middle Aged; Polycystic Ovary Syndrome; Risk Factors; Testosterone; Uric Acid

2021
Cabergoline-Induced Hypoprolactinemia May Attenuate Cardiometabolic Effects of Atorvastatin: A Pilot Study.
    Cardiology, 2022, Volume: 147, Issue:5-6

    Topics: Androgens; Atorvastatin; C-Reactive Protein; Cabergoline; Cardiovascular Diseases; Female; Fibrinogen; Homocysteine; Humans; Insulin Resistance; Pilot Projects; Prolactin; Risk Factors; Uric Acid

2022
Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes.
    Journal of neuroinflammation, 2023, Sep-01, Volume: 20, Issue:1

    Topics: Alzheimer Disease; Animals; Atorvastatin; Cognition; Cognitive Dysfunction; Dementia, Vascular; Homocysteine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Mice

2023