Compounds > atorvastatin
Page last updated: 2024-08-24

atorvastatin and fluorouracil

atorvastatin has been researched along with fluorouracil in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Mistafa, O; Stenius, U1
Peters, GJ; Schneiders, FL; van den Berg, HP; van der Vliet, HJ; Verheul, HM1
Alencar, NM; Barboza, DR; Brito, GA; Gomes, AS; Leitão, RF; Macedo, RN; Medeiros, CA; Nogueira, NA; Ribeiro, RA1
Högberg, J; Miraglia, E; Stenius, U1
Dai, Q; Ge, Y; He, S; Jia, H; Wang, X; Xia, J; Zhou, M1

Reviews

1 review(s) available for atorvastatin and fluorouracil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for atorvastatin and fluorouracil

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Statins inhibit Akt/PKB signaling via P2X7 receptor in pancreatic cancer cells.
    Biochemical pharmacology, 2009, Nov-01, Volume: 78, Issue:9

    Topics: Apoptosis; Atorvastatin; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Fluorouracil; Gemcitabine; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pancreatic Neoplasms; Proto-Oncogene Proteins c-akt; Pyrroles; Receptors, Purinergic P2; Receptors, Purinergic P2X7; RNA, Small Interfering; Signal Transduction

2009
Severe toxicity of capecitabine following uncomplicated treatment with 5-fluorouracil/leucovorin.
    Medical oncology (Northwood, London, England), 2011, Volume: 28, Issue:4

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; Bisoprolol; Bone Neoplasms; Capecitabine; Colic; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Heptanoic Acids; Humans; Hypercholesterolemia; Ileus; Leucovorin; Lymphatic Metastasis; Middle Aged; Nausea; Pyrroles; Ventricular Premature Complexes; Vomiting

2011
Effect of atorvastatin on 5-fluorouracil-induced experimental oral mucositis.
    Cancer chemotherapy and pharmacology, 2011, Volume: 67, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Atorvastatin; Bacteremia; Chemical and Drug Induced Liver Injury; Cricetinae; Cytokines; Dose-Response Relationship, Drug; Fluorouracil; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukopenia; Male; Mesocricetus; Mouth Mucosa; Nitric Oxide Synthase Type II; Nitrites; Peroxidase; Pyrroles; Stomatitis; Sulfhydryl Compounds

2011
Statins exhibit anticancer effects through modifications of the pAkt signaling pathway.
    International journal of oncology, 2012, Volume: 40, Issue:3

    Topics: Antineoplastic Agents; Atorvastatin; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; DNA Damage; Etoposide; Fluorouracil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyrroles; Receptors, Purinergic P2X; Signal Transduction

2012
Atorvastatin calcium alleviates 5-fluorouracil-induced intestinal damage by inhibiting cellular senescence and significantly enhances its antitumor efficacy.
    International immunopharmacology, 2023, Volume: 121

    Topics: Animals; Atorvastatin; Cellular Senescence; Colorectal Neoplasms; Endothelial Cells; Fluorouracil; Humans; Mice; Mice, Nude

2023