Compounds > atorvastatin
Page last updated: 2024-08-24

atorvastatin and estrone

atorvastatin has been researched along with estrone in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's9 (75.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Böhm, M; Draber, K; Eckel, L; Felix, SB; Grube, M; Jedlitschky, G; Köck, K; Kroemer, HK; Meissner, K; Oswald, S; Siegmund, W; Vogelgesang, S; Warzok, R1
Grime, K; Riley, RJ; Webborn, PJ1
Choi, MK; Choi, YL; Deng, JW; Shin, HJ; Shin, JG; Song, IS1
Chupka, J; Duignan, DB; El-Kattan, AF; Feng, B; Goosen, TC; Litchfield, J; Rotter, CJ; Varma, MV; Whalen, KM1
Cho, JY; Jang, IJ; Kim, SE; Kim, TE; Lee, MG; Shin, KH; Shin, SG; Song, IS; Yoon, SH; Yu, KS1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Li, L; Nouraldeen, A; Wilson, AG1
Grube, M; Keiser, M; Köck, K; Koenen, A; Kroemer, HK; Siegmund, W1
Ferreira, C; Hamburger, M; Meyer Zu Schwabedissen, HE; Oufir, M; Schaefer, AM; Seibert, I; Tirona, RG1
Foletti, A; Fuchs, A; Grube, M; Hussner, J; Malagnino, V; Meyer Zu Schwabedissen, HE; Schuler, E; Seibert, I1

Reviews

1 review(s) available for atorvastatin and estrone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for atorvastatin and estrone

ArticleYear
The effect of the newly developed angiotensin receptor II antagonist fimasartan on the pharmacokinetics of atorvastatin in relation to OATP1B1 in healthy male volunteers.
    Journal of cardiovascular pharmacology, 2011, Volume: 58, Issue:5

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Area Under Curve; Atorvastatin; Biphenyl Compounds; Cross-Over Studies; Drug Interactions; Estrone; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver-Specific Organic Anion Transporter 1; Male; Organic Anion Transporters; Pyrimidines; Pyrroles; RNA, Complementary; Tetrazoles; Young Adult

2011

Other Studies

10 other study(ies) available for atorvastatin and estrone

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart.
    Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:6

    Topics: Aged; Animals; Anticholesteremic Agents; Atorvastatin; Biological Transport; Dogs; Estrone; Female; Heart; Heptanoic Acids; Humans; Liver; Male; Myocardium; Organic Anion Transporters; Pyrroles; RNA, Ribosomal; Transfection

2006
Functional consequences of active hepatic uptake on cytochrome P450 inhibition in rat and human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:8

    Topics: Animals; Atorvastatin; Cells, Cultured; Culture Media; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme Inhibitors; Estrone; Hepatocytes; Heptanoic Acids; Humans; Hydroxylation; Liver; Midazolam; Pyrroles; Quinolines; Rats; Recombinant Proteins; Tritium

2008
Differential effect of genetic variants of Na(+)-taurocholate co-transporting polypeptide (NTCP) and organic anion-transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors.
    Xenobiotica; the fate of foreign compounds in biological systems, 2011, Volume: 41, Issue:1

    Topics: Animals; Atorvastatin; Estrone; Fluorobenzenes; Genetic Variation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver-Specific Organic Anion Transporter 1; Oocytes; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Pyrimidines; Pyrroles; Quinolines; Rosuvastatin Calcium; Sulfonamides; Symporters; Taurocholic Acid; Xenopus laevis

2011
pH-sensitive interaction of HMG-CoA reductase inhibitors (statins) with organic anion transporting polypeptide 2B1.
    Molecular pharmaceutics, 2011, Aug-01, Volume: 8, Issue:4

    Topics: Atorvastatin; Caco-2 Cells; Cell Line; Chromatography, Liquid; Estrone; Fatty Acids, Monounsaturated; Fluorobenzenes; Fluvastatin; Heptanoic Acids; Humans; Hydrogen-Ion Concentration; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Intestinal Absorption; Organic Anion Transporters; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Sulfonamides; Tandem Mass Spectrometry

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Evaluation of transporter-mediated hepatic uptake in a non-radioactive high-throughput assay: a study of kinetics, species difference and plasma protein effect.
    Xenobiotica; the fate of foreign compounds in biological systems, 2013, Volume: 43, Issue:3

    Topics: Animals; Atorvastatin; Biological Assay; Biological Transport; Blood Proteins; Cells, Cultured; Cryopreservation; Estrone; Female; Hepatocytes; Heptanoic Acids; High-Throughput Screening Assays; Humans; Kinetics; Liver; Male; Metformin; Organic Anion Transporters; Pravastatin; Pyrroles; Radioactivity; Reproducibility of Results; Species Specificity; Time Factors

2013
Steroid hormones specifically modify the activity of organic anion transporting polypeptides.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Nov-20, Volume: 47, Issue:4

    Topics: Atorvastatin; Biological Transport; Cell Line; Dehydroepiandrosterone Sulfate; Dexamethasone; Estrone; Glucocorticoids; Glyburide; HEK293 Cells; Heptanoic Acids; Hormones; Humans; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Progesterone; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Steroids

2012
Thyroid Hormones Are Transport Substrates and Transcriptional Regulators of Organic Anion Transporting Polypeptide 2B1.
    Molecular pharmacology, 2018, Volume: 94, Issue:1

    Topics: Animals; Atorvastatin; Biological Transport; Caco-2 Cells; Cell Line; Cell Line, Tumor; Dogs; Drug Interactions; Estrone; Genes, Reporter; HeLa Cells; Hep G2 Cells; Humans; Intestinal Absorption; Madin Darby Canine Kidney Cells; Organic Anion Transporters; Promoter Regions, Genetic; Thyroid Hormones; Transcription, Genetic

2018
Differences in transport function of the human and rat orthologue of the Organic Anion Transporting Polypeptide 2B1 (OATP2B1).
    Drug metabolism and pharmacokinetics, 2021, Volume: 41

    Topics: Animals; Atorvastatin; Biological Transport; Estrone; Humans; Intestinal Absorption; Organic Anion Transporters; Rats

2021