atorvastatin has been researched along with d-alpha tocopherol in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (8.33) | 18.2507 |
| 2000's | 16 (44.44) | 29.6817 |
| 2010's | 15 (41.67) | 24.3611 |
| 2020's | 2 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bachorik, PS | 1 |
| Ewy, GA | 1 |
| Joffe, BI; Kotze, MJ; Pilcher, GJ; Raal, FJ; Veller, MG | 1 |
| Lemmens, PJ; Oranje, WA; Rondas-Colbers, GJ; Sels, JP; Wolffenbuttel, BH | 1 |
| Bastagi, L; Boni, P; Massarelli, G; Muscari, A; Poggiopollini, G; Puddu, P; Tomassetti, V | 1 |
| Dixon, JL; Shen, S; Sturek, M; Sun, GY; Vuchetich, JP; Wysocka, E | 1 |
| Aleo, E; Dmitrieva, A; Littarru, GP; Passi, S; Stancato, A | 1 |
| Carlson, W; Clark, ME; Creager, M; Frei, B; Johnstone, M; Kinlay, S; Lloyd-Jones, DM; Maccallum, G; Orav, J; Rubenstein, J; Selwyn, AP; Sopko, G; Stone, PH | 1 |
| De Leeuw, I; Manuel-Y-Keenoy, B; Van Gaal, L; Vertommen, J; Vinckx, M | 1 |
| Ahotupa, M; Gylling, H; Miettinen, T; Nuotio, I; Strandberg, T; Tikkanen, MJ; Vanhanen, H; Vasankari, T; Viikari, J | 1 |
| Andrews, TC; Carlson, W; Cole, H; Creager, MA; Frei, B; Johnstone, M; Kinlay, S; Lloyd-Jones, DM; Orav, J; Rubenstein, J; Selwyn, AP; Sopko, G; Stone, PH | 1 |
| Bilo, HJ; Diepeveen, SH; Dikkeschei, LD; Kolsters, G; Offerman, JJ; Stalenhoef, AF; Van Der Palen, J; Van Tits, LJ; Verhoeven, GW | 1 |
| Bitto, A; Bonaiuto, A; Bonaiuto, M; Campo, S; Castaldo, M; Cinquegrani, M; Saitta, A; Saitta, C; Sardo, MA; Trimarchi, G | 1 |
| Arad, Y; Guerci, AD; Newstein, D; Roth, M; Spadaro, LA | 1 |
| Antoniades, C; Pitsavos, C; Stefanadis, C; Tentolouris, C; Tousoulis, D; Toutouza, M; Trikas, A; Vassiliadou, C | 1 |
| Antoniades, C; Stefanadis, C; Tousoulis, D | 1 |
| Antonini, R; Antonini, TM; Arca, M; Di Angelantonio, E; Diczfalusy, U; Iuliano, L; Micheletta, F; Montali, A; Natoli, S; Riggi, S | 1 |
| Cangemi, R; Carnevale, R; Loffredo, L; Pignatelli, P; Violi, F | 1 |
| Cangemi, R; Carnevale, R; Loffredo, L; Patrizi, MP; Perri, L; Pignatelli, P; Sanguigni, V; Violi, F | 1 |
| Jin, H; Koo, PT; Tsang, DJ; Xiao, H; Yang, CS; Yang, Z | 1 |
| Chang, LL; Chen, HW; Cheng, WL; Kuo, CL; Lii, CK; Liu, CS; Su, SL; Tsai, CW | 1 |
| Abd-Elghany, MI; Heeba, GH | 1 |
| Frank, J; Grebenstein, N; Hofmann, U; Podszun, MC | 1 |
| Ichinomiya, S; Iwata, H; Sato, H; Siddig, S; Suwa, E; Tuerdi, G; Ueno, K; Yano, T | 1 |
| Bergheim, I; Frank, J; Grebenstein, N; Kremoser, C; Podszun, MC; Schlueter, T; Spruss, A | 1 |
| Chen, X; Li, Y; Meng, Q; Sun, H; Xu, P; Yin, Q; Yu, H; Zhang, Z | 1 |
| Ishak, RA; Osman, R | 1 |
| Klyarytskaya, IL; Maksymova, EV; Stilidi, EI | 1 |
| Deng, L; Ding, Y; Fan, J; Huang, B; Peng, Y | 1 |
| Ghosh, SP; Hauer-Jensen, M; Pathak, R; Zhou, D | 1 |
| El-Yamany, MF; Farrag, SM; Hamzawy, MA; Nassar, NN; Saad, MA | 1 |
| Ipsen, DH; Klaebel, JH; Lykkesfeldt, J; Rakipovski, G; Schou-Pedersen, AMV; Skat-Rørdam, J; Skjødt, M; Tveden-Nyborg, P | 1 |
| Eser Faki, H; Tras, B; Uney, K | 1 |
| Jameshorani, M; Mellati, AA; Mousavi, SN; Rahimian, A; Rostamkhani, H; Tabaei, BS | 1 |
1 review(s) available for atorvastatin and d-alpha tocopherol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
15 trial(s) available for atorvastatin and d-alpha tocopherol
| Article | Year |
|---|---|
Effect of atorvastatin on LDL oxidation and antioxidants in normocholesterolemic type 2 diabetic patients.
Topics: Aged; Anticholesteremic Agents; Antioxidants; Atorvastatin; Blood Glucose; Cholesterol, LDL; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glycated Hemoglobin; Heptanoic Acids; Humans; Lipids; Male; Middle Aged; Oxidation-Reduction; Pyrroles; Ubiquinone; Vitamin E | 2001 |
Short term effect of atorvastatin and vitamin E on serum levels of C3, a sensitive marker of the risk of myocardial infarction in men.
Topics: Anticholesteremic Agents; Antioxidants; Atorvastatin; Biomarkers; Cholesterol, HDL; Complement C3c; Double-Blind Method; Drug Therapy, Combination; Heptanoic Acids; Humans; Male; Middle Aged; Myocardial Infarction; Pyrroles; Risk Factors; Vitamin E | 2001 |
Vascular basis for the treatment of myocardial ischemia study: trial design and baseline characteristics.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Antioxidants; Ascorbic Acid; Atorvastatin; Brachial Artery; Cholesterol, LDL; Double-Blind Method; Female; Heptanoic Acids; Humans; Male; Middle Aged; Myocardial Ischemia; Pyrroles; Regional Blood Flow; Ultrasonography; Vasodilation; Vitamin E | 2004 |
Impact of Vitamin E supplementation on lipoprotein peroxidation and composition in Type 1 diabetic patients treated with Atorvastatin.
Topics: Adult; Aged; alpha-Tocopherol; Antioxidants; Atorvastatin; Diabetes Mellitus, Type 1; Dietary Supplements; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Lipoproteins; Male; Middle Aged; Pyrroles | 2004 |
Effect of 12-month statin therapy on antioxidant potential of LDL and serum antioxidant vitamin concentrations.
Topics: alpha-Tocopherol; Atorvastatin; beta Carotene; Cholesterol, LDL; Chromatography, High Pressure Liquid; Female; gamma-Tocopherol; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Pyrroles; Simvastatin | 2004 |
Effect of intensive lipid lowering, with or without antioxidant vitamins, compared with moderate lipid lowering on myocardial ischemia in patients with stable coronary artery disease: the Vascular Basis for the Treatment of Myocardial Ischemia Study.
Topics: Angina Pectoris; Antioxidants; Ascorbic Acid; Atorvastatin; Coronary Artery Disease; Diet Therapy; Dose-Response Relationship, Drug; Exercise Test; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Lipids; Lipoproteins, LDL; Male; Myocardial Ischemia; Pyrroles; Vasomotor System; Vitamin E | 2005 |
Effects of atorvastatin and vitamin E on lipoproteins and oxidative stress in dialysis patients: a randomised-controlled trial.
Topics: Adult; alpha-Tocopherol; Apolipoproteins B; Atorvastatin; Cholesterol; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Lipoproteins; Lipoproteins, LDL; Male; Middle Aged; Oxidative Stress; Peritoneal Dialysis; Pyrroles; Renal Dialysis; Statistics, Nonparametric; Triglycerides | 2005 |
Antioxidant effect of atorvastatin is independent of PON1 gene T(-107)C, Q192R and L55M polymorphisms in hypercholesterolaemic patients.
Topics: Anticholesteremic Agents; Aryldialkylphosphatase; Atorvastatin; Cholesterol, LDL; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Oxidation-Reduction; Placebos; Polymorphism, Genetic; Promoter Regions, Genetic; Pyrroles; Vitamin E | 2005 |
Treatment of asymptomatic adults with elevated coronary calcium scores with atorvastatin, vitamin C, and vitamin E: the St. Francis Heart Study randomized clinical trial.
Topics: Aged; alpha-Tocopherol; Antioxidants; Ascorbic Acid; Aspirin; Atorvastatin; Calcinosis; Coronary Artery Disease; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyrroles; Tomography, X-Ray Computed | 2005 |
Effects of combined administration of low dose atorvastatin and vitamin E on inflammatory markers and endothelial function in patients with heart failure.
Topics: Aged; Antioxidants; Atorvastatin; Biomarkers; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelium, Vascular; Follow-Up Studies; Heart Failure; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Male; Pyrroles; Treatment Outcome; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Vasodilation; Vitamin E | 2005 |
Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: reduction during atorvastatin and fenofibrate therapy.
Topics: Adult; alpha-Tocopherol; Atorvastatin; Biomarkers; Drug Combinations; Female; Fenofibrate; Heptanoic Acids; Humans; Hydroxycholesterols; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Ketocholesterols; Lipids; Lipoproteins; Male; Middle Aged; Models, Biological; Oxidative Stress; Pyrroles | 2007 |
Early decrease of oxidative stress by atorvastatin in hypercholesterolaemic patients: effect on circulating vitamin E.
Topics: Anticholesteremic Agents; Atorvastatin; Blood Platelets; Cholesterol, LDL; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Isoprostanes; Male; Middle Aged; NADPH Oxidases; Oxidative Stress; Pyrroles; Superoxides; Vitamin E | 2008 |
Atorvastatin increases blood ratios of vitamin E/low-density lipoprotein cholesterol and coenzyme Q10/low-density lipoprotein cholesterol in hypercholesterolemic patients.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Deoxyguanosine; Erythrocytes; Female; Glutathione; Heptanoic Acids; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Oxidative Stress; Pyrroles; Ubiquinone; Vitamin E | 2010 |
[COMPARISON OF DIFFERENT TREATMENT REGIMENS IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE].
Topics: Adult; Aged; Atorvastatin; Female; Humans; Interleukin-6; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid; Vitamin E | 2015 |
Co-Administration of Vitamin E and Atorvastatin Improves Insulin Sensitivity and Peroxisome Proliferator-Activated Receptor-γ Expression in Type 2 Diabetic Patients: A Randomized Double-Blind Clinical Trial.
Topics: Atorvastatin; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Insulin Resistance; Leukocytes, Mononuclear; PPAR gamma; Vitamin E | 2022 |
20 other study(ies) available for atorvastatin and d-alpha tocopherol
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Therapy and clinical trials.
Topics: Antioxidants; Arteriosclerosis; Atorvastatin; Clinical Trials as Topic; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Pyrroles; Vitamin A; Vitamin E | 1998 |
Antioxidant therapy for coronary artery disease: don't paint the walls without treating the termites!
Topics: Angioplasty, Balloon, Coronary; Anticholesteremic Agents; Antioxidants; Atorvastatin; Cholesterol, LDL; Coronary Disease; Heptanoic Acids; Humans; Lung Neoplasms; Oxidation-Reduction; Prospective Studies; Pyrroles; Randomized Controlled Trials as Topic; Risk; Survival Analysis; Treatment Outcome; Vitamin A; Vitamin E | 1999 |
Efficacy of vitamin E compared with either simvastatin or atorvastatin in preventing the progression of atherosclerosis in homozygous familial hypercholesterolemia.
Topics: Adolescent; Adult; Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Carotid Arteries; Child; Child, Preschool; Cholesterol, HDL; Cholesterol, LDL; Disease Progression; DNA; Female; Heptanoic Acids; Homozygote; Humans; Hyperlipoproteinemia Type II; Male; Mutation; Pyrroles; Receptors, LDL; Simvastatin; Treatment Outcome; Triglycerides; Tunica Intima; Vitamin E | 1999 |
Increased atherosclerosis in diabetic dyslipidemic swine: protection by atorvastatin involves decreased VLDL triglycerides but minimal effects on the lipoprotein profile.
Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Blood Glucose; Cholesterol; Collagen; Diabetes Mellitus, Experimental; Diet, Atherogenic; Fasting; Heptanoic Acids; Hyperlipidemias; Insulin; Lipoproteins, VLDL; Liver; Male; Pyrroles; Swine; Swine, Miniature; Triglycerides; Vitamin A; Vitamin E | 2002 |
Statins lower plasma and lymphocyte ubiquinol/ubiquinone without affecting other antioxidants and PUFA.
Topics: Antioxidants; Atorvastatin; Catalase; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coenzymes; Erythrocytes; Fatty Acids, Unsaturated; Glutathione; Glutathione Peroxidase; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lymphocytes; Male; Middle Aged; Pravastatin; Pyrroles; Simvastatin; Superoxide Dismutase; Ubiquinone; Vitamin E | 2003 |
Statins and antioxidant vitamins: should co-administration be avoided?
Topics: Antioxidants; Ascorbic Acid; Atorvastatin; Calcinosis; Cardiovascular Diseases; Coronary Disease; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Vitamin E | 2006 |
Statins enhance circulating vitamin E.
Topics: Atorvastatin; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metabolic Syndrome; Middle Aged; Oxidative Stress; Pyrroles; Retrospective Studies; Simvastatin; Vitamin E | 2008 |
Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells.
Topics: Atorvastatin; Celecoxib; Cell Cycle; Cell Division; Cell Line, Tumor; Chromans; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Drug Synergism; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Polyisoprenyl Phosphates; Pyrazoles; Pyrroles; Sulfonamides; Vitamin E | 2010 |
Effect of combined administration of ginger (Zingiber officinale Roscoe) and atorvastatin on the liver of rats.
Topics: Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Antioxidants; Atorvastatin; Catalase; Chemical and Drug Induced Liver Injury; Cholesterol; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Heptanoic Acids; Liver; Male; Malondialdehyde; Nitric Oxide; Phytotherapy; Plant Extracts; Pyrroles; Random Allocation; Rats; Rats, Wistar; Rhizome; Superoxide Dismutase; Transaminases; Vitamin E; Zingiber officinale | 2010 |
High-dose supplementation with natural α-tocopherol does neither alter the pharmacodynamics of atorvastatin nor its phase I metabolism in guinea pigs.
Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Atorvastatin; Blotting, Western; Cholesterol; Cytochrome P-450 CYP3A; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; Heptanoic Acids; Liver; Pyrroles; Random Allocation | 2013 |
Synergistic effect of combined treatment with gamma-tocotrienol and statin on human malignant mesothelioma cells.
Topics: Apoptosis; Atorvastatin; Caspase 3; Cell Line, Tumor; Cell Proliferation; Chromans; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Enzyme Activation; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mesothelioma; Metabolic Networks and Pathways; Mevalonic Acid; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Simvastatin; Vitamin E | 2013 |
Dietary α-tocopherol and atorvastatin reduce high-fat-induced lipid accumulation and down-regulate CD36 protein in the liver of guinea pigs.
Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Atorvastatin; CD36 Antigens; Dietary Supplements; Down-Regulation; Guinea Pigs; Heptanoic Acids; Lipid Metabolism; Liver; Oxidative Stress; Pyrroles; Receptors, LDL; Triglycerides; Ubiquitination | 2014 |
Hydrogen-bonded and reduction-responsive micelles loading atorvastatin for therapy of breast cancer metastasis.
Topics: Animals; Atorvastatin; Breast; Breast Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Female; Heptanoic Acids; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Micelles; Oxidation-Reduction; Polyethylene Glycols; Pyrroles; Vitamin E | 2014 |
Lecithin/TPGS-based spray-dried self-microemulsifying drug delivery systems: In vitro pulmonary deposition and cytotoxicity.
Topics: Administration, Inhalation; Aerosols; Atorvastatin; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Desiccation; Dose-Response Relationship, Drug; Drug Carriers; Drug Stability; Emulsions; Humans; Inhibitory Concentration 50; Lecithins; Lung; Lung Neoplasms; Particle Size; Polyethylene Glycols; Powders; Solubility; Surface-Active Agents; Technology, Pharmaceutical; Vitamin E | 2015 |
Gamma-tocotrienol reverses multidrug resistance of breast cancer cells with a mechanism distinct from that of atorvastatin.
Topics: Antineoplastic Agents; Apoptosis; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Chromans; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Hydroxymethylglutaryl CoA Reductases; MCF-7 Cells; Membrane Potential, Mitochondrial; Mevalonic Acid; Reactive Oxygen Species; Vitamin E | 2017 |
The Vitamin E Analog Gamma-Tocotrienol (GT3) and Statins Synergistically Up-Regulate Endothelial Thrombomodulin (TM).
Topics: Antioxidants; Atorvastatin; Cell Line; Chromans; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kruppel-Like Transcription Factors; Reverse Transcriptase Polymerase Chain Reaction; Thrombomodulin; Up-Regulation; Vitamin E | 2016 |
Atorvastatin in nano-particulate formulation abates muscle and liver affliction when coalesced with coenzyme Q10 and/or vitamin E in hyperlipidemic rats.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Atorvastatin; Drug Compounding; Hyperlipidemias; Liver; Male; Muscles; Nanoparticles; Oxidative Stress; Rats; Rats, Wistar; Ubiquinone; Vitamin E; Vitamins | 2018 |
Atorvastatin and Vitamin E Accelerates NASH Resolution by Dietary Intervention in a Preclinical Guinea Pig Model.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Atorvastatin; Caloric Restriction; Combined Modality Therapy; Female; Guinea Pigs; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation Mediators; Lipids; Liver; Liver Cirrhosis, Experimental; Non-alcoholic Fatty Liver Disease; Time Factors; Vitamin E | 2019 |
Alpha lipoic acid and vitamin E improve atorvastatin-induced mitochondrial dysfunctions in rats.
Topics: Adenosine Triphosphate; Administration, Oral; Animals; Atorvastatin; Case-Control Studies; Disease Models, Animal; Kidney; Male; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Rats; Rats, Wistar; Thioctic Acid; Treatment Outcome; Vitamin E | 2020 |