Page last updated: 2024-08-24

atorvastatin and amyloid beta-peptides

atorvastatin has been researched along with amyloid beta-peptides in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blennow, K; Eikenberg, O; Höglund, K; Vanderstichele, H; Vanmechelen, E; Wiklund, O1
Crisby, M; Lindberg, C; Schultzberg, M; Winblad, B1
Adler, C; Browne, P; Connor, D; Lochhead, J; Lopez, J; Petanceska, S; Sabbagh, M; Soares, H; Sparks, DL; Ziolkowski, C1
Bezerra, SC; de Bem, AF; Duarte, FS; Figueiredo, CP; Mancini, G; Piermartiri, TC; Prediger, RD; Rial, D; Tasca, CI1
Butterfield, DA1
Araki, W; Hosaka, A; Oda, A; Tamaoka, A; Tomidokoro, Y1
Dal-Cim, TA; de Oliveira, KA; dos Santos, AA; dos Santos, VV; Farina, M; Martins, WC; Mendes-de-Aguiar, CB; Prediger, RD; Tasca, CI; Vandresen-Filho, S; Viola, GG1

Reviews

1 review(s) available for atorvastatin and amyloid beta-peptides

ArticleYear
Atorvastatin and Aβ(1-40): not as simple as cholesterol reduction in brain and relevance to Alzheimer disease.
    Experimental neurology, 2011, Volume: 228, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Atorvastatin; Brain; Cholesterol; Heptanoic Acids; Humans; Peptide Fragments; Pyrroles

2011

Trials

2 trial(s) available for atorvastatin and amyloid beta-peptides

ArticleYear
Plasma levels of beta-amyloid(1-40), beta-amyloid(1-42), and total beta-amyloid remain unaffected in adult patients with hypercholesterolemia after treatment with statins.
    Archives of neurology, 2004, Volume: 61, Issue:3

    Topics: Adult; Aged; Amyloid beta-Peptides; Anticholesteremic Agents; Atorvastatin; Cross-Over Studies; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Lipids; Male; Middle Aged; Peptide Fragments; Prospective Studies; Pyrroles; Simvastatin; Time Factors

2004
Cholesterol, copper and Abeta in controls, MCI, AD and the AD cholesterol-lowering treatment trial (ADCLT).
    Current Alzheimer research, 2005, Volume: 2, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Atorvastatin; Ceruloplasmin; Cholesterol; Cholinergic Antagonists; Cognition Disorders; Copper; Cross-Sectional Studies; Heptanoic Acids; Humans; Longitudinal Studies; Middle Aged; Peptide Fragments; Pyrroles; Verbal Learning

2005

Other Studies

4 other study(ies) available for atorvastatin and amyloid beta-peptides

ArticleYear
Effects of statins on microglia.
    Journal of neuroscience research, 2005, Oct-01, Volume: 82, Issue:1

    Topics: Amyloid beta-Peptides; Animals; Atorvastatin; Cell Death; Cell Line; Cell Survival; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; L-Lactate Dehydrogenase; Lipopolysaccharides; Microglia; Peptide Fragments; Pyrroles; Rats; Simvastatin; Statistics, Nonparametric; Tetrazolium Salts; Thiazoles

2005
Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β(1-40) administration in mice: evidence for dissociation between cognitive deficits and neuronal damage.
    Experimental neurology, 2010, Volume: 226, Issue:2

    Topics: Amino Acid Transport System X-AG; Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Newborn; Astrocytes; Atorvastatin; Cell Death; Cyclooxygenase 2; Encephalitis; Fluoresceins; Gene Expression Regulation; Glutamic Acid; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Heptanoic Acids; Hippocampus; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Learning Disabilities; Male; Maze Learning; Memory Disorders; Mice; Nerve Tissue Proteins; Neurons; Organic Chemicals; Oxidative Stress; Peptide Fragments; Propidium; Pyrroles; Tritium

2010
Statins reduce amyloid β-peptide production by modulating amyloid precursor protein maturation and phosphorylation through a cholesterol-independent mechanism in cultured neurons.
    Neurochemical research, 2013, Volume: 38, Issue:3

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Atorvastatin; Cholesterol; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Neurons; Peptide Fragments; Phosphorylation; Pyrroles; Quinolines; Rats

2013
Atorvastatin Prevents Cognitive Deficits Induced by Intracerebroventricular Amyloid-β1-40 Administration in Mice: Involvement of Glutamatergic and Antioxidant Systems.
    Neurotoxicity research, 2015, Volume: 28, Issue:1

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Animals; Atorvastatin; Cognition Disorders; Glutamic Acid; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusions, Intraventricular; Male; Mice; Oxidative Stress; Peptide Fragments; Prefrontal Cortex; Recognition, Psychology; Spatial Learning; Spatial Memory

2015