atomoxetine hydrochloride has been researched along with n-desmethylatomoxetine in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eckstein, JA; Gillespie, JS; Ring, BJ; Wrighton, SA | 1 |
| Belle, DJ; Ernest, CS; Sauer, JM; Smith, BP; Thomasson, HR; Witcher, JW | 1 |
| Aznar, G; Farrè, M; Garcia-Algar, O; Marchei, E; Mortali, C; Pacifici, R; Papaseit, E; Pichini, S | 1 |
| Bae, JW; Choi, CI; Jang, CG; Lee, HI; Lee, SY; Sohn, UD | 1 |
| Bae, JW; Choi, CI; Jang, CG; Lee, HI; Lee, SY; Lee, YJ | 1 |
| Bae, JW; Byeon, JY; Chung, MW; Jang, CG; Jang, JH; Kim, IS; Kim, SH; Kim, YH; Lee, SY; Lee, YJ; Na, HS | 1 |
2 trial(s) available for atomoxetine hydrochloride and n-desmethylatomoxetine
| Article | Year |
|---|---|
Effect of potent CYP2D6 inhibition by paroxetine on atomoxetine pharmacokinetics.
Topics: Administration, Oral; Adult; Area Under Curve; Atomoxetine Hydrochloride; Blood Pressure; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Drug Interactions; Female; Heart Rate; Humans; Male; Middle Aged; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Phenols; Phenyl Ethers; Propylamines; Selective Serotonin Reuptake Inhibitors; Single-Blind Method; Symporters; Time Factors | 2002 |
Effects of the CYP2D6*10 allele on the pharmacokinetics of atomoxetine and its metabolites.
Topics: Adrenergic Uptake Inhibitors; Adult; Alleles; Area Under Curve; Atomoxetine Hydrochloride; Chromatography, Liquid; Cytochrome P-450 CYP2D6; Genotype; Half-Life; Humans; Male; Phenols; Phenyl Ethers; Propylamines; Tandem Mass Spectrometry; Young Adult | 2015 |
4 other study(ies) available for atomoxetine hydrochloride and n-desmethylatomoxetine
| Article | Year |
|---|---|
Identification of the human cytochromes P450 responsible for atomoxetine metabolism.
Topics: Aryl Hydrocarbon Hydroxylases; Atomoxetine Hydrochloride; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Complementary; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Isoenzymes; Microsomes, Liver; Mixed Function Oxygenases; Phenols; Phenyl Ethers; Propylamines; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization | 2002 |
Development and validation of a liquid chromatography-tandem mass spectrometry assay for hair analysis of atomoxetine and its metabolites: Application in clinical practice.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Child; Chromatography, Liquid; Female; Hair; Humans; Male; Medication Adherence; Phenols; Phenyl Ethers; Propylamines; Tandem Mass Spectrometry | 2012 |
Determination of atomoxetine metabolites in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study.
Topics: Atomoxetine Hydrochloride; Chromatography, Liquid; Drug Stability; Humans; Male; Phenols; Phenyl Ethers; Propylamines; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Young Adult | 2012 |
Effects of CYP2C19 genetic polymorphisms on atomoxetine pharmacokinetics.
Topics: Administration, Oral; Adrenergic Uptake Inhibitors; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Atomoxetine Hydrochloride; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Genotype; Half-Life; Humans; Male; Metabolic Clearance Rate; Pharmacogenetics; Phenols; Phenotype; Phenyl Ethers; Polymorphism, Genetic; Propylamines; Tandem Mass Spectrometry | 2014 |