atenolol has been researched along with sq-11725 in 97 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 38 (39.18) | 18.7374 |
1990's | 20 (20.62) | 18.2507 |
2000's | 18 (18.56) | 29.6817 |
2010's | 19 (19.59) | 24.3611 |
2020's | 2 (2.06) | 2.80 |
Authors | Studies |
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Carrupt, PA; el Tayar, N; Testa, B; Van de Waterbeemd, H | 1 |
Topliss, JG; Yoshida, F | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
Baker, JG | 1 |
Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Bard, B; Carrupt, PA; Martel, S | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Campillo, NE; Guerra, A; Páez, JA | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Avdeef, A; Tam, KY | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
Lipworth, BJ; McDevitt, DG; Wheeldon, NM | 3 |
Bousser, MG; Massiou, H | 1 |
Hirakawa, S; Imai, Y; Ito, H; Kakami, M; Koshiji, M; Minatoguchi, S; Watanabe, H | 1 |
Almotrefi, AA; Dzimiri, N | 1 |
Murano, M; Naruto, S; Noguchi, H; Yoshida, K | 1 |
Allavena, A; Brambilla, G; Gazzaniga, GM; Martelli, A; Mazzei, M; Robbiano, L | 1 |
Irvine, NA; Lipworth, BJ; McDevitt, DG | 1 |
Cherchi, A; Sau, F; Seguro, C | 1 |
Brammell, HL; Hiatt, WR; Horwitz, LD; Travis, V; Wolfel, EE | 1 |
Kostis, JB | 2 |
Bertino, JS; Corsi, CM; Nafziger, AN; Pieper, JA | 1 |
Cleroux, J; Leenen, FH; Taylor, AW; Van Nguyen, P | 1 |
From, RP; Mehta, MP; Pathak, D | 1 |
Brammell, HL; Hiatt, WR; Horwitz, LD; Nies, AS; Stoll, S; Wolfel, EE; Zerbe, GO | 1 |
Fletcher, GF | 1 |
McDevitt, DG | 1 |
Ansuini, R; Belogi, M; Gaggi, S; Pupita, F; Pupita, G | 1 |
Fishbein, L; Jackson, CD | 1 |
Charyev, KhE; Iurenev, AP; Shkhvatsabaia, IK | 1 |
Baylor, P; Fildes, J; Gerst, PH; Zonszein, J | 1 |
Epstein, M; Oster, JR | 1 |
Brammell, HL; Carry, MR; Hiatt, WR; Horwitz, LD; Ringel, SP; Travis, V; Wolfel, EE | 1 |
Burris, JF; Goldstein, J; Plachetka, JR; Sirgo, MA; Sutton, JM; Zager, PG | 1 |
Alexopoulos, D; Cobbe, SM; Manley, BS; Robinson, GJ | 1 |
Harvengt, C; Heller, FR; Martiat, P; Van Nieuwenhuyze, Y | 1 |
Bonsignore, MR; Culver, PL; Dodek, PM; Jerome, EH; Staub, NC | 1 |
Coelho, J; Garg, DC; Hitzenberger, G; Irwin, C; Kaik, G; Klausner, MA; Magometschnigg, D; Mullane, JF; Ventura, DF; Weidler, DJ | 1 |
Cox, DA; Leader, JP; Milson, JA; Singleton, W | 1 |
Vidt, DG | 1 |
Frishman, WH; Koch-Weser, J | 1 |
Burmeister, WE; Lee, RJ; Reynolds, RD | 1 |
Mattioli, G; Menozzi, A; Ricci, S; Teglio, V | 1 |
Hampton, JR; Wilcox, RG | 1 |
Iskandrian, AS; Kotler, MN; Segal, BL | 1 |
Fregly, MJ | 1 |
Laher, MS; McGarry, K; O'Brien, E; O'Callaghan, WG; O'Malley, K | 1 |
Charyev, KhE; Erina, EV | 1 |
Desiatnichenko, VM; Romakov, AIu; Sagirov, AM; Sobol', IuS; Sumarokov, AB | 1 |
Jackson, EA; Sullman, SA | 1 |
Lucchesi, BR; Patterson, E | 1 |
Chung, DC; Laschuk, MJ | 1 |
Beaulieu, G; Grimes, D; Muirhead, C; Oshiro, G | 1 |
Peele, ME; Shulkin, BL; Utiger, RD | 1 |
McGoon, MD; Vlietstra, RE | 1 |
Cosgrove, NM; Kostis, JB; Krieger, SD; Lacy, CR | 1 |
Abed, J; Donaldson, R; Nashat, F; Taggart, P | 1 |
Anderson, S; Brater, DC; Kaplan, NM; Ram, CV | 1 |
Beebe, HG; Messina, LM; Moursi, MM; Stanley, JC; Welling, TH | 1 |
Dykstra, LA; Fecho, K; Lysle, DT | 1 |
Kurosawa, H; Taira, N; Yanagisawa, T | 1 |
Davies, RA; Fourney, A; Leenen, FH | 1 |
de Castro, B; Gameiro, P; Guimarães, C; Lima, JL; Reis, S | 2 |
Azevedo, ER; Newton, GE; Parker, JD | 1 |
Belhassen, B; Dorostkar, PC; Eldar, M; Scheinman, MM | 1 |
Andrews, ML; Benhorin, J; Crampton, RS; Hall, WJ; Locati, EH; Medina, A; Moss, AJ; Napolitano, C; Priori, SG; Robinson, JL; Schwartz, PJ; Timothy, K; Towbin, JA; Vincent, GM; Zareba, W; Zhang, L | 1 |
Chauhan, V; Hegele, RA; Klein, GJ; Krahn, AD; Skanes, AC; Wang, J; Yee, R | 1 |
Andersson, KK; Barra, AL; Engalytcheff, A; Kolberg, M; Tilquin, B | 1 |
Al-Ghannam, SM | 1 |
DE Magalhaes, LP; Fagundes, A; Russo, M; Xavier, E | 1 |
Massarsky, A; Moon, TW; Trudeau, VL | 1 |
Cooper, WJ; Song, W; Wang, L; Xu, H | 1 |
Figueroa, JJ; Fischer, PR; Gehrking, JA; Iodice, V; Kimpinski, K; Low, PA; Opfer-Gehrking, TL; Sandroni, P; Singer, W; Sletten, DM | 1 |
Abu-Zeitone, A; McNitt, S; Moss, AJ; Peterson, DR; Polonsky, B | 1 |
Fruge, JH; Massengale, WT; Rouhana, HF | 1 |
Demir, Y | 1 |
Jacobsen, SJ; Kalantar-Zadeh, K; Kovesdy, CP; Lee, MS; Neyer, JR; Shaw, SF; Shi, J; Sim, JJ; Zhou, H | 1 |
Ballotari, M; Gottardo, R; Tagliaro, F; Taus, F; Utzeri, C | 1 |
11 review(s) available for atenolol and sq-11725
Article | Year |
---|---|
Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Models, Molecular; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1988 |
[Beta-blockers and migraine].
Topics: Adrenergic beta-Antagonists; Atenolol; Clinical Trials as Topic; Dilatation, Pathologic; Evoked Potentials, Visual; Humans; Metoprolol; Migraine Disorders; Nadolol; Platelet Aggregation; Propranolol; Receptors, Serotonin; Timolol | 1992 |
A toxicological review of beta-adrenergic blockers.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol | 1986 |
Beta blockers and renal function: a reappraisal.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Urea Nitrogen; Cardiac Output; Creatinine; Dogs; Glomerular Filtration Rate; Heart; Humans; Hypertension; Kidney; Labetalol; Metoprolol; Nadolol; Propanolamines; Propranolol; Renal Circulation; Renin; Sympathomimetics; Vascular Resistance | 1985 |
Advances in the medical management of renovascular hypertension.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Atenolol; Captopril; Dipeptides; Enalapril; Female; Humans; Hypertension, Renovascular; Male; Metoprolol; Middle Aged; Nadolol; Pindolol; Propanolamines; Propranolol; Renal Artery Obstruction; Renin-Angiotensin System; Saralasin; Timolol | 1984 |
beta-Adrenoceptor antagonists: new drugs and new indications.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Glaucoma; Humans; Hypertension; Kinetics; Metoprolol; Migraine Disorders; Nadolol; Pindolol; Propanolamines; Propranolol; Timolol | 1981 |
[Hemodynamic changes caused by beta-blocking agents with and without intrinsic sympathicomimetic activity and with and without cardioselective activity. Comparison of hypertensives at fixed and variable frequencies].
Topics: Adrenergic beta-Antagonists; Atenolol; Female; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Nadolol; Pindolol; Propanolamines | 1982 |
Comparative review of beta-blocking agents.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Atenolol; Humans; Hypertension; Metoprolol; Migraine Disorders; Myocardial Infarction; Nadolol; Pindolol; Propanolamines; Propranolol; Timolol | 1984 |
The new beta-adrenergic antagonists.
Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Labetalol; Metoprolol; Nadolol; Oxprenolol; Pindolol; Propanolamines; Timolol | 1984 |
β-blockers as endocrine disruptors: the potential effects of human β-blockers on aquatic organisms.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Endocrine Disruptors; Fishes; Gluconeogenesis; Glucose; Glycogenolysis; Insulin; Insulin Secretion; Lipolysis; Metoprolol; Molecular Structure; Mollusca; Muscle Contraction; Nadolol; Propranolol; Species Specificity; Water Pollutants, Chemical | 2011 |
Beta blocker treatment for infantile hemangiomas.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Atenolol; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Hemangioma, Capillary; Humans; Infant; Male; Nadolol; Propranolol; Skin Neoplasms; Timolol; Treatment Outcome | 2015 |
22 trial(s) available for atenolol and sq-11725
Article | Year |
---|---|
Selectivity of antagonist and partial agonist activity of celiprolol in normal subjects.
Topics: Adult; Atenolol; Celiprolol; Dose-Response Relationship, Drug; Heart Rate; Humans; Male; Nadolol; Physical Exertion; Potassium; Receptors, Adrenergic, beta; Single-Blind Method; Tremor | 1992 |
[Beta-blockers and migraine].
Topics: Adrenergic beta-Antagonists; Atenolol; Clinical Trials as Topic; Dilatation, Pathologic; Evoked Potentials, Visual; Humans; Metoprolol; Migraine Disorders; Nadolol; Platelet Aggregation; Propranolol; Receptors, Serotonin; Timolol | 1992 |
A dose-ranging study to evaluate the beta 1-adrenoceptor selectivity of bisoprolol.
Topics: Adrenergic beta-Antagonists; Adult; Analysis of Variance; Atenolol; Bisoprolol; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Male; Nadolol; Propanolamines; Single-Blind Method; Statistics as Topic; Tremor | 1991 |
Plasma catecholamine responses to exercise after training with beta-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Epinephrine; Exercise; Humans; Male; Nadolol; Norepinephrine; Physical Education and Training | 1990 |
Beta-blocker duration of action and implications for therapy.
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Atenolol; Circadian Rhythm; Double-Blind Method; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Nadolol; Pindolol | 1990 |
Lack of effect of atenolol and nadolol on the metabolism of theophylline.
Topics: Adult; Atenolol; Drug Interactions; Half-Life; Humans; Male; Nadolol; Smoking; Theophylline | 1990 |
Effects of beta 1- vs. beta 1 + beta 2-blockade on exercise endurance and muscle metabolism in humans.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Catecholamines; Clinical Trials as Topic; Double-Blind Method; Glycogen; Hemodynamics; Humans; Male; Muscles; Nadolol; Physical Endurance; Potassium; Triglycerides | 1989 |
beta-2 Adrenergic blockade evaluated with epinephrine after placebo, atenolol, and nadolol.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Epinephrine; Heart Rate; Humans; Leg; Male; Nadolol; Propanolamines; Random Allocation; Vascular Resistance | 1985 |
Beta-blockers and psychometric performance: studies in normal volunteers.
Topics: Adrenergic beta-Antagonists; Atenolol; Diazepam; Dose-Response Relationship, Drug; Humans; Lipid Metabolism; Nadolol; Oxazepam; Propanolamines; Propranolol; Psychometrics; Psychomotor Performance; Random Allocation; Reaction Time; Reference Values; Solubility; Time Factors | 1985 |
Controlled trial on three beta-blockers: antihypertensive efficacy and effect on the hypertensive heart disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Blood Pressure; Clinical Trials as Topic; Electrocardiography; Female; Heart Diseases; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nadolol; Oxprenolol; Propanolamines; Risk | 1985 |
Effects of selective and nonselective beta-adrenergic blockade on mechanisms of exercise conditioning.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Exercise Test; Hemodynamics; Humans; Lactates; Lactic Acid; Male; Muscles; Nadolol; Oxygen Consumption; Physical Education and Training; Plethysmography; Random Allocation | 1986 |
Comparative tolerability of labetalol versus propranolol, atenolol, pindolol, metoprolol, and nadolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nadolol; Pindolol; Propranolol | 1986 |
The antihypertensive effects of doxazosin: a clinical overview.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Double-Blind Method; Doxazosin; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Kinetics; Male; Metoprolol; Middle Aged; Nadolol; Prazosin; Propanolamines; Random Allocation; Risk; Triglycerides | 1986 |
Comparison of the duration of action of atenolol and nadolol for treatment of angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Atenolol; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Nadolol; Placebos; Random Allocation; Time Factors | 1988 |
Comparison between atenolol and nadolol in essential hypertension at rest and on exercise.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Exercise Test; Heart Rate; Humans; Hypertension; Middle Aged; Nadolol; Peak Expiratory Flow Rate; Physical Exertion; Propanolamines | 1982 |
Antihypertensive and renal haemodynamic effects of atenolol and nadolol in elderly hypertensive patients.
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Blood Pressure; Female; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nadolol; Propanolamines; Renal Circulation | 1983 |
[Comparative evaluation of the therapeutic effect of various classes of beta-blockaders in patients with hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Clinical Trials as Topic; Echocardiography; Heart; Hemodynamics; Humans; Hypertension; Labetalol; Middle Aged; Nadolol; Propanolamines; Propranolol | 1983 |
Atenolol, nadolol, and pindolol in angina pectoris on effort: effect of pharmacokinetics.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Electrocardiography; Half-Life; Heart Rate; Humans; Kinetics; Male; Nadolol; Physical Exertion; Pindolol; Propanolamines; Time Factors | 1984 |
Do beta 3-adrenoceptors mediate metabolic responses to isoprenaline.
Topics: Adult; Atenolol; Basal Metabolism; Fatty Acids, Nonesterified; Female; Glucose; Glycerol; Humans; Insulin; Isoproterenol; Lactates; Lactic Acid; Male; Nadolol; Receptors, Adrenergic, beta; Respiration | 1993 |
Investigation of putative cardiac beta 3-adrenoceptors in man.
Topics: Adult; Atenolol; Blood Flow Velocity; Blood Pressure; Female; Heart; Heart Rate; Humans; Isoproterenol; Male; Nadolol; Receptors, Adrenergic, beta; Stimulation, Chemical; Tremor | 1993 |
Catecholamines and heart function in heart transplant patients: effects of beta1- versus nonselective beta-blockade.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Confounding Factors, Epidemiologic; Cross-Over Studies; Double-Blind Method; Epinephrine; Female; Heart; Heart Function Tests; Heart Rate; Heart Transplantation; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nadolol; Norepinephrine; Stroke Volume | 1998 |
Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Child; Child, Preschool; Female; Humans; Infant; Long QT Syndrome; Male; Metoprolol; Nadolol; Propranolol; Survival Analysis | 2000 |
65 other study(ies) available for atenolol and sq-11725
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2005 |
Exploring the role of different drug transport routes in permeability screening.
Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Characterization of the drug binding specificity of rat liver fatty acid binding protein.
Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
A comparison of guanfacine, bunazosin, atenolol and nadolol on blood pressure and plasma noradrenaline responses to cold pressor testing.
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Atenolol; Blood Pressure; Cold Temperature; Guanfacine; Humans; Hypertension; Nadolol; Norepinephrine; Quinazolines; Receptors, Adrenergic; Stress, Physiological | 1992 |
Effects of beta-adrenoceptor blockers on mitochondrial ATPase activity in guinea pig heart preparations.
Topics: Adenosine Triphosphatases; Adrenergic beta-Antagonists; Animals; Atenolol; Female; Guinea Pigs; In Vitro Techniques; Indenes; Male; Mitochondria, Heart; Nadolol; Propanolamines | 1992 |
Determination of nadolol in serum by high-performance liquid chromatography with fluorimetric detection.
Topics: Atenolol; Chromatography, High Pressure Liquid; Humans; Nadolol; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1992 |
Formation of the N-nitroso derivatives of six beta-adrenergic-blocking agents and their genotoxic effects in rat and human hepatocytes.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Cell Survival; DNA; DNA Damage; DNA Repair; Humans; Liver; Male; Metoprolol; Nadolol; Nitrosamines; Nitrosation; Oxprenolol; Propranolol; Rats; Rats, Inbred Strains; Sodium Nitrite; Sotalol | 1991 |
[Effects of antihypertensive therapy with selective and non-selective beta blocking agents on dimensions and function of the left ventricle].
Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Blood Pressure; Echocardiography; Female; Heart Ventricles; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nadolol; Pindolol; Timolol; Ventricular Function | 1991 |
Serum potassium concentrations following succinylcholine in patients undergoing beta-adrenoceptor blocking therapy.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Blood Pressure; Heart Rate; Humans; Metoprolol; Middle Aged; Nadolol; Ophthalmic Solutions; Potassium; Propranolol; Succinylcholine; Time Factors; Timolol | 1989 |
Exercise training during chronic beta blockade in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Coronary Artery Bypass; Female; Heart Rate; Humans; Male; Metoprolol; Myocardial Infarction; Nadolol; Physical Exertion; Propanolamines; Propranolol; Timolol | 1985 |
[Regression of left-ventricular myocardial hypertrophy in patients with hypertension during long-term treatment with beta-adrenergic blockaders].
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atenolol; Cardiomegaly; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nadolol; Propanolamines; Propranolol; Time Factors | 1986 |
Long-acting beta-adrenergic antagonists as preparation for surgery in thyrotoxicosis.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Drug Administration Schedule; Female; Graves Disease; Humans; Middle Aged; Nadolol; Premedication; Propanolamines; Pulse; Thyroidectomy; Time Factors | 1986 |
Subsidiary class III effects of beta blockers? A comparison of atenolol, metoprolol, nadolol, oxprenolol and sotalol.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atenolol; Dose-Response Relationship, Drug; Isomerism; Metoprolol; Muscle Contraction; Nadolol; Oxprenolol; Papillary Muscles; Rabbits; Refractory Period, Electrophysiological; Sotalol | 1986 |
Short-term effects of beta blockers atenolol, nadolol, pindolol, and propranolol on lipoprotein metabolism in normolipemic subjects.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Apolipoproteins; Atenolol; Humans; Lipids; Lipoprotein Lipase; Lipoproteins; Liver; Male; Nadolol; Pindolol; Propranolol | 1987 |
Effects of beta-adrenergic agents in lungs of normal and air-embolized awake sheep.
Topics: Adrenergic beta-Agonists; Animals; Atenolol; Blood Pressure; Blood Proteins; Cardiac Output; Embolism, Air; Female; Lung; Lymph; Nadolol; Propranolol; Proteins; Pulmonary Circulation; Reference Values; Sheep | 1988 |
Cardioselectivity of cetamolol compared with atenolol and nadolol.
Topics: Acetamides; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Heart; Heart Rate; Humans; Isoproterenol; Male; Nadolol; Physical Exertion | 1988 |
Limitation of myocardial infarct size by atenolol, nadolol and propranolol in dogs.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Dogs; Female; Heart; Heart Rate; Male; Membranes; Myocardial Infarction; Nadolol; Propanolamines; Propranolol | 1981 |
Managing angina with beta blockers.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Humans; Metoprolol; Nadolol; Nitrates; Propanolamines; Propranolol; Timolol | 1982 |
An attempt to characterize the beta-adrenoceptor subtype mediating tail skin temperature response of rats to acute administration of isoproterenol.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Butoxamine; Dose-Response Relationship, Drug; Female; Isoproterenol; Nadolol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Skin Temperature; Tail | 1983 |
[Comparative study of the action of a series of new beta-adrenergic receptor blockaders in patients with effort angina].
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Atenolol; Echocardiography; Exercise Test; Hemodynamics; Humans; Labetalol; Male; Middle Aged; Nadolol; Propanolamines; Propranolol | 1983 |
Antifibrillatory properties of the beta-adrenergic receptor antagonists, nadolol, sotalol, atenolol and propranolol, in the anesthetized dog.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Atenolol; Dogs; Dose-Response Relationship, Drug; Heart Conduction System; Male; Nadolol; Propanolamines; Propranolol; Sotalol; Ventricular Fibrillation | 1984 |
Cetamolol: cardiovascular effects of a new cardioselective beta-adrenoceptor blocker possessing partial agonistic activity and lacking membrane-stabilizing activity.
Topics: Acetamides; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Atenolol; Cats; Coronary Circulation; Dogs; Hemodynamics; Isoproterenol; Macaca mulatta; Membranes; Myocardium; Nadolol; Organ Specificity; Oxygen Consumption; Pindolol; Propanolamines; Propranolol; Stroke Volume; Vascular Resistance | 1984 |
Beta-adrenergic antagonist inhibition of hepatic 3,5,3'-triiodothyronine production.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Dithiothreitol; Liver; Male; Metoprolol; Nadolol; Pindolol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Timolol; Triiodothyronine | 1984 |
Beta-adrenergic blockers. Choosing among them.
Topics: Adrenergic beta-Antagonists; Atenolol; Cardiovascular Diseases; Humans; Kinetics; Metoprolol; Nadolol; Pindolol; Propanolamines; Propranolol; Timolol | 1984 |
Class III action of beta-blocking agents.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atenolol; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Female; Heart; Heart Ventricles; Male; Nadolol; Oxprenolol; Pindolol; Propanolamines; Propranolol; Sotalol; Timolol | 1984 |
Beta-adrenergic blockade alone does not decrease renal perfusion in black hypertensives.
Topics: Adrenergic beta-Antagonists; Atenolol; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Kidney; Male; Nadolol; Propanolamines; Propranolol; Renin | 1984 |
Inhibition of aortic aneurysm development in blotchy mice by beta adrenergic blockade independent of altered lysyl oxidase activity.
Topics: Animals; Aorta, Thoracic; Aortic Aneurysm; Atenolol; Blood Pressure; Heart Rate; Male; Mice; Mice, Mutant Strains; Nadolol; Propranolol; Protein-Lysine 6-Oxidase | 1995 |
Evidence for beta adrenergic receptor involvement in the immunomodulatory effects of morphine.
Topics: Animals; Atenolol; Cell Division; Immunosuppressive Agents; Leukocyte Count; Leukocytes; Male; Mitogens; Morphine; Nadolol; Propanolamines; Rats; Rats, Inbred Lew; Receptors, Adrenergic, beta; Spleen; Sympathetic Nervous System | 1993 |
Biphasic antagonisms by beta-blockers against positive inotropic response through beta1-adrenoceptors in isolated canine right ventricular muscles: possible involvement of two beta 1-adrenoceptor subtypes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Bisoprolol; Dogs; Dose-Response Relationship, Drug; Ethanolamines; Female; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nadolol; Papillary Muscles; Receptors, Adrenergic, beta-1; Stimulation, Chemical | 1996 |
Fluorimetric and solubility studies of nadolol and atenolol in SDS micelles.
Topics: Adrenergic beta-Antagonists; Atenolol; Fluorometry; Micelles; Nadolol; Sodium Dodecyl Sulfate; Solubility; Spectrometry, Fluorescence | 1998 |
Inotropic and sympathetic responses to the intracoronary infusion of a beta2-receptor agonist: a human in vivo study.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Albuterol; Atenolol; Cardiac Catheterization; Chest Pain; Coronary Disease; Coronary Vessels; Female; Heart; Heart Ventricles; Hemodynamics; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Myocardial Contraction; Nadolol; Norepinephrine; Sympathetic Nervous System; Sympathomimetics | 1999 |
Long-term follow-up of patients with long-QT syndrome treated with beta-blockers and continuous pacing.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Child; Child, Preschool; Cohort Studies; Death, Sudden; Electric Countershock; Female; Follow-Up Studies; Humans; Incidence; Infant; Infant, Newborn; Long QT Syndrome; Male; Metoprolol; Middle Aged; Nadolol; Pacemaker, Artificial; Prognosis; Propranolol; Risk Assessment; Survival Analysis; Treatment Outcome | 1999 |
Partition coefficients of beta-blockers in bile salt/lecithin micelles as a tool to assess the role of mixed micelles in gastrointestinal absorption.
Topics: Adrenergic beta-Antagonists; Algorithms; Atenolol; Bile Acids and Salts; Chemical Phenomena; Chemistry, Physical; Indicators and Reagents; Intestinal Absorption; Micelles; Nadolol; Phosphatidylcholines; Potentiometry; Solubility; Solutions; Spectrometry, Fluorescence | 2001 |
Beta blockers normalize QT hysteresis in long QT syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Analysis of Variance; Anti-Arrhythmia Agents; Atenolol; Case-Control Studies; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Long QT Syndrome; Male; Nadolol | 2002 |
The use of multi-frequency EPR techniques to identify the radicals produced in irradiated beta-blockers.
Topics: Adrenergic beta-Antagonists; Atenolol; Electron Spin Resonance Spectroscopy; Free Radicals; Nadolol; Propanolamines; Propranolol; Temperature | 2004 |
A simple spectrophotometric method for the determination of beta-blockers in dosage forms.
Topics: Adrenergic beta-Antagonists; Atenolol; Bromcresol Purple; Bromphenol Blue; Bromthymol Blue; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chloroform; Coloring Agents; Dose-Response Relationship, Drug; Ions; Kinetics; Models, Chemical; Nadolol; Spectrophotometry, Ultraviolet; Tablets; Thermodynamics; Timolol | 2006 |
Pharmacological treatment of electrical storm in cathecolaminergic polymorphic ventricular tachycardia.
Topics: Adolescent; Anti-Arrhythmia Agents; Atenolol; Defibrillators, Implantable; Drug Therapy, Combination; Electrocardiography; Exercise Test; Humans; Male; Nadolol; Quality of Life; Syncope; Tachycardia, Ventricular; Verapamil | 2010 |
Photochemical fate of beta-blockers in NOM enriched waters.
Topics: Adrenergic beta-Antagonists; Atenolol; Hydrogen-Ion Concentration; Kinetics; Metoprolol; Nadolol; Photochemical Processes; Soil; Sunlight; Water Pollutants, Chemical | 2012 |
A prospective, 1-year follow-up study of postural tachycardia syndrome.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adult; Anti-Inflammatory Agents; Atenolol; Cholinesterase Inhibitors; Female; Fludrocortisone; Follow-Up Studies; Heart Rate; Humans; Male; Metoprolol; Midodrine; Nadolol; Norepinephrine; Postural Orthostatic Tachycardia Syndrome; Propranolol; Prospective Studies; Pyridostigmine Bromide; Severity of Illness Index; Sodium; Tilt-Table Test; Virus Diseases | 2012 |
Efficacy of different beta-blockers in the treatment of long QT syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Child; Child, Preschool; Death, Sudden, Cardiac; Female; Genotype; Heart Arrest; Humans; Infant; Infant, Newborn; Long QT Syndrome; Male; Metoprolol; Multivariate Analysis; Nadolol; Proportional Hazards Models; Propranolol; Registries; Regression Analysis; Risk Factors; Syncope; Time Factors; Treatment Outcome; Young Adult | 2014 |
The behaviour of some antihypertension drugs on human serum paraoxonase-1: an important protector enzyme against atherosclerosis.
Topics: Antihypertensive Agents; Aryldialkylphosphatase; Atenolol; Atherosclerosis; Humans; Lipoproteins, HDL; Midodrine; Nadolol; Pindolol | 2019 |
β-Blocker Use and Risk of Mortality in Heart Failure Patients Initiating Maintenance Dialysis.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Atenolol; Bisoprolol; Carvedilol; Cause of Death; Cohort Studies; Female; Heart Failure; Hospitalization; Humans; Kidney Failure, Chronic; Labetalol; Logistic Models; Male; Metoprolol; Middle Aged; Mortality; Nadolol; Proportional Hazards Models; Propranolol; Protective Factors; Renal Dialysis; Retrospective Studies; Risk; Risk Factors | 2021 |
Hair analysis for beta-blockers and calcium-channel blockers by using liquid chromatography-tandem mass spectrometry as a tool for monitoring adherence to antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Amlodipine; Antihypertensive Agents; Atenolol; Bisoprolol; Calcium; Calcium Channel Blockers; Chromatography, Liquid; Hair Analysis; Humans; Labetalol; Metoprolol; Nadolol; Nebivolol; Reproducibility of Results; Sotalol; Tandem Mass Spectrometry | 2022 |