atenolol has been researched along with oxprenolol in 90 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (61.11) | 18.7374 |
| 1990's | 13 (14.44) | 18.2507 |
| 2000's | 13 (14.44) | 29.6817 |
| 2010's | 8 (8.89) | 24.3611 |
| 2020's | 1 (1.11) | 2.80 |
| Authors | Studies |
|---|---|
| Carrupt, PA; Gaillard, P; Schambel, P; Testa, B | 1 |
| Artursson, P; Beigi, F; Lundahl, P; Luthman, K; Palm, K; Strandlund, G; Ungell, AL | 1 |
| Ghuloum, AM; Jain, AN; Sage, CR | 1 |
| Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Ertl, P; Rohde, B; Selzer, P | 1 |
| Artursson, P; Luthman, K; Norinder, U; Stenberg, P | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Caron, G; Ermondi, G | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Bard, B; Carrupt, PA; Martel, S | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Barritt, DW; Marshall, AJ; Roberts, CJ | 1 |
| Barritt, DW; Marshall, A; Roberts, CJ | 1 |
| Harry, JD; Knapp, MF; Linden, RJ; Newcombe, CP; Stoker, JB | 1 |
| Brown, HC; Carruthers, SG; McDevitt, DG; Shanks, RG | 1 |
| Erdmann, E; Krawietz, W; Pruchniewski, M; Weinsteiger, M | 1 |
| Dickerson, DD; Fulmor, IE; Goldberg, ME; Lee, RJ | 1 |
| Day, MD; Roach, AG | 1 |
| Bühler, FR; Burkart, F; Marbet, G; Patel, U | 1 |
| Lüderitz, B | 1 |
| Kiechel, JR; Meier, J | 1 |
| Bellucci, R; Bonomi, L; Massa, F; Noya, E; Perfetti, S | 1 |
| Brown, B; Buckley, M; Darragh, A; Fitzgerald, D; Foley, JE; O'Kelly, D; Tormey, W; Vukovich, RA; Willard, DA | 1 |
| Harry, JD; Knapp, MF; Linden, RJ; Newcombe, C; Stoker, JB | 1 |
| Barritt, DW; Heaton, ST; Marshall, AJ; Pocock, J | 1 |
| Davidson, C; Myint, S; singleton, W; Taylor, SH; Thadani, U | 1 |
| Chatterjee, SS; Croxson, RS; Cruickshank, JM; Perks, WH | 1 |
| Brocklehurst, JE; Turner, AS; Watson, OF | 1 |
| Jancinová, V; Nosál, R; Petríková, M | 1 |
| Does, RJ; Roos, JM; Tan, ES; Van Baak, MA; Volovics, A | 1 |
| Allavena, A; Brambilla, G; Gazzaniga, GM; Martelli, A; Mazzei, M; Robbiano, L | 1 |
| Enquist, M; Hermansson, J | 1 |
| Fiocchi, G; Fogari, R; Poletti, L; Rizzardi, G; Tettamanti, F; Zoppi, A | 1 |
| Herlitz, H | 1 |
| Jackson, PR; Lewis, RV; Ramsay, LE | 2 |
| Chiba, S; Kobayashi, M; Shimotori, M | 1 |
| Kawecka-Jaszcz, K; Skoczeń, M | 1 |
| Cruickshank, JM; Neil-Dwyer, G | 1 |
| Hawksworth, GM; Petrie, JC; Rigby, JW; Scott, AK | 1 |
| Ansuini, R; Belogi, M; Gaggi, S; Pupita, F; Pupita, G | 1 |
| Fishbein, L; Jackson, CD | 1 |
| Belpaire, FM; Bogaert, MG; Mugabo, P; Rosseel, MT | 1 |
| Dal Negro, RW; Pomari, C; Trevisan, F; Turco, P; Zoccatelli, O | 1 |
| Alexopoulos, D; Cobbe, SM; Manley, BS; Robinson, GJ | 1 |
| Desager, JP; Harvengt, C; Heller, F; Hulhoven, R | 1 |
| Deighton, N; Howie, CA; Jones, CR; Reid, JL; Sumner, DJ; Whyte, K | 1 |
| Foëx, P; Johnson, LL; Khambatta, HJ; Sear, JW; Stone, JG; Triner, L | 1 |
| Oosterhuis, B; van Baak, MA; Verstappen, FT | 1 |
| Jutrin, I; Lang, R; Ravid, M | 1 |
| Hampton, JR | 1 |
| Hampton, JR; Wilcox, RG | 1 |
| Wilcox, RG | 1 |
| Day, JL; Metcalfe, J; Simpson, CN | 1 |
| Henderson, A; Lewis, M; Ross, J; Sheridan, D | 1 |
| Eide, I; Eriksen, IL; Foss, OP; Holme, I; Kjeldsen, SE; Leren, P | 1 |
| Hatori, Y; Horii, M; Nakamura, Y; Nemoto, E; Otsuka, K; Sakai, T; Tsukiyama, H; Yamamoto, Y; Yamato, T; Yoshii, Y | 1 |
| Ermakova, VN | 1 |
| Cherenshchikova, EA; Filippov, AK; Iuzhakov, SD; Mashkovskiĭ, MD; Porotikov, VI | 1 |
| Chung, DC; Laschuk, MJ | 1 |
| Friedewald, WT; Frishman, WH; Furberg, CD | 1 |
| Rubin, PC | 1 |
| Abed, J; Donaldson, R; Nashat, F; Taggart, P | 1 |
| Aakesson, I; Eide, I; Kjeldsen, SE; Leren, P; Os, I; Skjøtø, J | 1 |
| Silke, B; Taylor, SH; Watt, SJ | 1 |
| Aakesson, I; Amundsen, R; Eide, I; Eriksen, IL; Kjeldsen, SE; Leren, P | 1 |
| Hausen, T | 1 |
| Jeffers, TA; Petrie, JC; Robb, OJ; Scott, AK; Webster, J | 1 |
| Balasubramanian, V; Mann, S; Millar-Craig, MW; Raftery, EB | 1 |
| Ambrosioni, E; Costa, FV; Magnani, B; Marata, AM; Montebugnoli, L; Rosati, G | 1 |
| Bullimore, DW | 1 |
| Arnhold, J; Arnold, K; Seifert, T; Zschörnig, O | 1 |
| Gemba, M; Hosaka, K; Kamiyama, M; Kobayashi, I; Konno, C; Maruo, H; Ueno, T | 1 |
| Caldwell, GW; Evangelisto, M; Masucci, JA; White, R | 1 |
| Caldwell, GW; Demarest, K; Easlick, SM; Gunnet, J; Masucci, JA | 1 |
| Mizogami, M; Takakura, K; Tsuchiya, H | 1 |
| Jiang, X; Sun, N; Xi, Y; Zhang, Y | 1 |
| Esler, M; Grassi, G; Kjeldsen, SE; Kreutz, R; Mancia, G; Pathak, A | 1 |
9 review(s) available for atenolol and oxprenolol
| Article | Year |
|---|---|
[Comparative pharmacokinetics of beta-blockers].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Timolol | 1978 |
ACE-inhibitors and quality of life.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Captopril; Enalapril; Health Status; Humans; Hypertension; Methyldopa; Middle Aged; Oxprenolol; Quality of Life | 1990 |
[Beta-blockaders in the treatment of hypertension in pregnancy].
Topics: Adrenergic beta-Antagonists; Atenolol; Drug Evaluation; Female; Humans; Hypertension; Metoprolol; Oxprenolol; Pindolol; Pregnancy; Pregnancy Complications, Cardiovascular; Propranolol | 1985 |
A toxicological review of beta-adrenergic blockers.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol | 1986 |
The use of beta blockers for the reduction of mortality after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Myocardial Infarction; Norway; Oxprenolol; Practolol; Propranolol; Random Allocation; Timolol | 1981 |
The new beta-adrenergic antagonists.
Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Labetalol; Metoprolol; Nadolol; Oxprenolol; Pindolol; Propanolamines; Timolol | 1984 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol | 1984 |
Comparative efficacy of β-blockers on mortality and cardiovascular outcomes in patients with hypertension: a systematic review and network meta-analysis.
Topics: Adrenergic beta-Antagonists; Age Factors; Antihypertensive Agents; Atenolol; Coronary Disease; Humans; Hydrophobic and Hydrophilic Interactions; Hypertension; Incidence; Metoprolol; Network Meta-Analysis; Oxprenolol; Propranolol; Stroke; Treatment Outcome | 2017 |
Diverse pharmacological properties, trial results, comorbidity prescribing and neural pathophysiology suggest European hypertension guideline downgrading of beta-blockers is not justified.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Cardiovascular Diseases; Comorbidity; Heart Failure; Humans; Hypertension; Metoprolol; Oxprenolol; Propranolol | 2022 |
25 trial(s) available for atenolol and oxprenolol
| Article | Year |
|---|---|
A test which may demonstrate in man, intrinsic sympathomimetic activity of beta-adrenoceptor blocking drugs [proceedings].
Topics: Adrenergic beta-Antagonists; Atenolol; Heart Rate; Humans; Oxprenolol; Physical Exertion; Practolol; Propranolol; Sympathomimetics | 1975 |
Effect of beta-blockers on exercise double product (systolic blood pressure x heart rate).
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Drug Evaluation; Heart Rate; Humans; Kinetics; Male; Middle Aged; Oxprenolol; Physical Exertion; Pindolol; Propanolamines; Propranolol; Time Factors; Timolol | 1979 |
Effects of 4 beta-adrenoceptor blocking drugs on blood pressure and exercise heart rate in hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Depression, Chemical; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxprenolol; Practolol; Propranolol | 1979 |
Evaluation of beta blockade bendrofluazide, and prazosin in severe hypertension.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxprenolol; Prazosin; Propranolol; Quinazolines | 1977 |
Anti-dysrhythmic treatment in acute myocardial infarction.
Topics: Acute Disease; Administration, Oral; Atenolol; Clinical Trials as Topic; Disopyramide; Double-Blind Method; Humans; Injections, Intravenous; Lidocaine; Myocardial Infarction; Oxprenolol; Propranolol; Ventricular Fibrillation | 1979 |
Comparison of atenolol and oxprenolol in patients with angina or hypertension and co-existent chronic airways obstruction.
Topics: Adult; Airway Obstruction; Angina Pectoris; Atenolol; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxprenolol; Propanolamines; Respiration; Respiratory Function Tests | 1978 |
Efficacy of atenolol and oxprenolol in the treatment of arterial hypertension. A comparison.
Topics: Adult; Aged; Atenolol; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypertension; Middle Aged; Oxprenolol; Placebos; Propanolamines | 1979 |
An interactive computer program for randomization analysis of response curves with facilities for multiple comparisons.
Topics: Adult; Atenolol; Exercise; Female; Heart Rate; Humans; Male; Oxprenolol; Random Allocation; Software; Software Design | 1992 |
Comparative effects of celiprolol, propranolol, oxprenolol, and atenolol on respiratory function in hypertensive patients with chronic obstructive lung disease.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Celiprolol; Forced Expiratory Volume; Humans; Hypertension; Lung; Lung Diseases, Obstructive; Male; Middle Aged; Oxprenolol; Propanolamines; Propranolol | 1990 |
Controlled trial on three beta-blockers: antihypertensive efficacy and effect on the hypertensive heart disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Blood Pressure; Clinical Trials as Topic; Electrocardiography; Female; Heart Diseases; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nadolol; Oxprenolol; Propanolamines; Risk | 1985 |
Respiratory effects of four adrenergic blocking agents combined with a diuretic in treating hypertension with concurrent chronic obstructive lung disease.
Topics: Adrenergic beta-Antagonists; Airway Resistance; Atenolol; Chlorthalidone; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Hypertension; Labetalol; Lung Diseases, Obstructive; Male; Maximal Midexpiratory Flow Rate; Metoprolol; Oxprenolol; Random Allocation | 1986 |
Haemodynamic, metabolic, and lymphocyte beta 2-adrenoceptor changes following chronic beta-adrenoceptor antagonism.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Hemodynamics; Humans; Lymphocytes; Oxprenolol; Potassium; Propranolol; Random Allocation; Receptors, Adrenergic, beta | 1987 |
Myocardial ischemia in untreated hypertensive patients: effect of a single small oral dose of a beta-adrenergic blocking agent.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Anesthesia; Atenolol; Clinical Trials as Topic; Coronary Disease; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Oxprenolol; Preanesthetic Medication; Random Allocation | 1988 |
Twenty-four hour effects of oxprenolol Oros and atenolol on heart rate, blood pressure, exercise tolerance and perceived exertion.
Topics: Adult; Atenolol; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Male; Oxprenolol; Physical Endurance; Random Allocation | 1986 |
The relative antihypertensive potency of propranolol, oxprenolol, atenolol, and metoprolol given once daily. A double-blind, crossover, placebo-controlled study in ambulatory patients.
Topics: Adult; Aged; Analysis of Variance; Atenolol; Blood Pressure; Body Weight; Delayed-Action Preparations; Double-Blind Method; Drug Evaluation; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Oxprenolol; Physical Exertion; Propranolol; Prospective Studies; Pulse | 1985 |
The use of beta blockers for the reduction of mortality after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Myocardial Infarction; Norway; Oxprenolol; Practolol; Propranolol; Random Allocation; Timolol | 1981 |
Comparative study of atenolol, metoprolol, metoprolol durules, and slow-release oxprenolol in essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Oxprenolol; Physical Exertion; Random Allocation | 1981 |
Acute intervention studies in patients with myocardial infarction using atenolol, propranolol, oxprenolol and disopyramide phosphate.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Clinical Trials as Topic; Disopyramide; Double-Blind Method; Electrocardiography; Female; Humans; Male; Middle Aged; Myocardial Infarction; Oxprenolol; Propranolol; Pyridines | 1981 |
Adrenergic mechanisms in control of plasma lipid concentrations.
Topics: Adrenergic beta-Antagonists; Atenolol; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Fatty Acids, Nonesterified; Female; Humans; Hypertension; Lipids; Lipoproteins, HDL; Lipoproteins, VLDL; Male; Metoprolol; Oxprenolol; Propranolol; Random Allocation; Triglycerides | 1982 |
The effect on HDL cholesterol of oxprenolol and atenolol.
Topics: Adrenergic beta-Antagonists; Atenolol; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Heart Rate; Humans; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Oxprenolol; Propanolamines; Triglycerides | 1982 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol | 1984 |
Increased plasma vasopressin and serum uric acid in the low renin type of essential hypertension.
Topics: Atenolol; Blood Pressure; Body Weight; Catecholamines; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxprenolol; Renin; Uric Acid; Vasopressins | 1984 |
Can once-daily beta-blockade provide 24-hour cardioprotection?
Topics: Adult; Atenolol; Delayed-Action Preparations; Drug Administration Schedule; Hemodynamics; Humans; Male; Middle Aged; Oxprenolol | 1983 |
Increased plasma free dopamine after treatment with atenolol and oxprenolol in essential hypertension.
Topics: Atenolol; Dopamine; Epinephrine; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Oxprenolol; Posture | 1983 |
Atenolol, sustained-release oxprenolol, and long-acting propranolol in hypertension.
Topics: Adult; Atenolol; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Oxprenolol; Propanolamines; Propranolol; Random Allocation | 1980 |
58 other study(ies) available for atenolol and oxprenolol
| Article | Year |
|---|---|
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes | 1996 |
Evaluation of dynamic polar molecular surface area as predictor of drug absorption: comparison with other computational and experimental predictors.
Topics: Adrenergic beta-Antagonists; Amides; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Drug Design; Epithelial Cells; Formamides; Humans; Intestinal Absorption; Liposomes; Models, Molecular; Molecular Conformation; Monte Carlo Method; Permeability; Propanolamines; Structure-Activity Relationship | 1998 |
Molecular hashkeys: a novel method for molecular characterization and its application for predicting important pharmaceutical properties of molecules.
Topics: Drug Design; Intestinal Absorption; Models, Molecular; Pharmaceutical Preparations; Structure-Activity Relationship | 1999 |
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties.
Topics: Biological Availability; Biological Transport; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results | 2000 |
Experimental and computational screening models for the prediction of intestinal drug absorption.
Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Raynaud's phenomenon as side effect of beta-blockers in hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Oxprenolol; Propranolol; Raynaud Disease; Skin Temperature | 1976 |
Letter: Raynaud's phenomenon as side effect of beta-blockers.
Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Oxprenolol; Propranolol; Raynaud Disease | 1976 |
Influence of intrinsic sympathomimetic activity and cardioselectivity on beta adrenoceptor blockade.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Humans; Male; Oxprenolol; Physical Exertion; Practolol; Propranolol; Sotalol; Sympathomimetics; Time Factors | 1977 |
[Properties of beta-adrenergic receptors of heart and lung--studies with "cardioselective" beta-receptor blocking substances].
Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Binding, Competitive; Heart; Lung; Metoprolol; Oxprenolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1977 |
Direct myocardial depressant effects of several beta-adrenergic blocking agents in the unanesthetized atherosclerotic rabbit.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Arteriosclerosis; Atenolol; Blood Pressure; Depression, Chemical; Heart Rate; Isoproterenol; Male; Oxprenolol; Pindolol; Propanolamines; Propranolol; Rabbits; Timolol | 1978 |
The brain as a possible site for the cardiovascular effects of beta-adrenoceptor blocking agents in cats.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Blood Pressure; Brain; Cats; Female; Heart Rate; Injections, Intraventricular; Male; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol | 1975 |
Renin-suppressive potency of various beta-adrenergic blocking agents at supine rest and during upright exercise.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Humans; Male; Oxprenolol; Physical Exertion; Pindolol; Posture; Practolol; Propranolol; Renin; Timolol | 1975 |
[beta-receptor blockaders in cardiac arrhythmias].
Topics: Adrenergic beta-Antagonists; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atenolol; Bradycardia; Electrocardiography; Heart Ventricles; Humans; Oxprenolol; Sinoatrial Node; Tachycardia, Paroxysmal | 1978 |
Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Drug Tolerance; Ethanolamines; Intraocular Pressure; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rabbits; Sotalol; Timolol | 1979 |
A comparative study of the activity of beta-adrenoceptor antagonists in man.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Heart Rate; Humans; Isoproterenol; Male; Middle Aged; Oxprenolol; Phenyl Ethers; Physical Exertion; Practolol; Propanolamines; Propranolol | 1975 |
On the relationship between the inhibition of thrombin stimulated aggregation and thromboxane formation in isolated platelets treated with beta-adrenoceptor blocking drugs.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Arachidonic Acid; Atenolol; Blood Platelets; Male; Membrane Fluidity; Metipranolol; Oxprenolol; Platelet Aggregation Inhibitors; Practolol; Propranolol; Rats; Rats, Wistar; Thrombin; Thromboxane A2 | 1992 |
Formation of the N-nitroso derivatives of six beta-adrenergic-blocking agents and their genotoxic effects in rat and human hepatocytes.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Cell Survival; DNA; DNA Damage; DNA Repair; Humans; Liver; Male; Metoprolol; Nadolol; Nitrosamines; Nitrosation; Oxprenolol; Propranolol; Rats; Rats, Inbred Strains; Sodium Nitrite; Sotalol | 1991 |
Separation of the enantiomers of beta-receptor blocking agents and other cationic drugs using a CHIRAL-AGP column. Binding properties and characterization of immobilized alpha 1-acid glycoprotein.
Topics: Adrenergic beta-Antagonists; Adsorption; Alprenolol; Atenolol; Binding Sites; Butylamines; Chromatography; Metoprolol; Molecular Structure; Orosomucoid; Oxprenolol; Pindolol; Propranolol; Protein Conformation; Spectrometry, Fluorescence; Stereoisomerism | 1990 |
Side-effects of beta-adrenoceptor blocking drugs assessed by visual analogue scales.
Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Metoprolol; Oxprenolol; Propranolol; Surveys and Questionnaires | 1985 |
Comparative study of five beta-adrenoceptor blocking agents on sinoatrial conduction time in isolated blood-perfused canine atria.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Carteolol; Dogs; In Vitro Techniques; Oxprenolol; Propranolol; Sinoatrial Node; Sotalol | 1985 |
Beta-blocker brain concentrations in man.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Brain Chemistry; Cats; Humans; Lipid Metabolism; Metoprolol; Oxprenolol; Propranolol; Rats; Solubility; Species Specificity; Subarachnoid Hemorrhage; Tissue Distribution | 1985 |
Side-effects of beta-blockers assessed using visual analogue scales.
Topics: Acebutolol; Adrenergic beta-Antagonists; Analysis of Variance; Atenolol; Dreams; Fatigue; Humans; Hypertension; Metoprolol; Oxprenolol; Propranolol | 1985 |
A comparison of the pharmacokinetics of atenolol, metoprolol, oxprenolol and propranolol in elderly hypertensive and young healthy subjects.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Atenolol; Blood Proteins; Female; Half-Life; Humans; Hypertension; Kinetics; Male; Metoprolol; Oxprenolol; Propranolol; Protein Binding | 1985 |
Binding to serum alpha 1-acid glycoprotein and effect of beta-adrenoceptor antagonists in rats with inflammation.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Heart Rate; Inflammation; Injections, Intravenous; Male; Metoprolol; Orosomucoid; Oxprenolol; Portal Vein; Propranolol; Protein Binding; Rats; Rats, Inbred Strains | 1986 |
Subsidiary class III effects of beta blockers? A comparison of atenolol, metoprolol, nadolol, oxprenolol and sotalol.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atenolol; Dose-Response Relationship, Drug; Isomerism; Metoprolol; Muscle Contraction; Nadolol; Oxprenolol; Papillary Muscles; Rabbits; Refractory Period, Electrophysiological; Sotalol | 1986 |
Beta-blocking agents and plasma lipids: an update.
Topics: 1-Propanol; Adrenergic beta-Antagonists; Atenolol; Cholesterol, LDL; Coronary Disease; Humans; Hypertension; Lipids; Lipoproteins, HDL; Lipoproteins, HDL2; Lipoproteins, LDL; Oxprenolol; Penbutolol; Pindolol; Sotalol | 1987 |
Factors relating to the beta blocker withdrawal syndrome.
Topics: Acebutolol; Adrenergic beta-Antagonists; Atenolol; Coronary Disease; Heart Rate; Humans; Hyperthyroidism; Oxprenolol; Propranolol; Substance Withdrawal Syndrome; Valsalva Maneuver | 1981 |
Possible significance of the pharmacological differentiation of beta-blocking agents in hemodynamic effects in essential hypertension.
Topics: Acebutolol; Adrenergic beta-Antagonists; Atenolol; Carteolol; Hemodynamics; Humans; Hypertension; Metoprolol; Oxprenolol; Propranolol | 1983 |
[Effect of beta-adrenoblockers on prostaglandin-induced ocular hypertension in rabbits].
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Dinoprostone; Male; Ocular Hypertension; Oxprenolol; Propanolamines; Propranolol; Prostaglandins E; Rabbits; Timolol | 1983 |
[Role of transmembrane ion currents in the mechanism of action of beta-adrenoblockers].
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Heart; Ion Channels; Labetalol; Oxprenolol; Pindolol; Propranolol; Rana ridibunda | 1984 |
Beta blockers in pregnancy.
Topics: Adrenergic beta-Antagonists; Atenolol; Female; Humans; Hypertension; Kinetics; Methyldopa; Oxprenolol; Pregnancy; Pregnancy Complications, Cardiovascular | 1984 |
Class III action of beta-blocking agents.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atenolol; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Female; Heart; Heart Ventricles; Male; Nadolol; Oxprenolol; Pindolol; Propanolamines; Propranolol; Sotalol; Timolol | 1984 |
[Withdrawal syndrome following beta blocker therapy (author's transl)].
Topics: Adult; Angina Pectoris; Atenolol; Chlorthalidone; Female; Humans; Hypertension; Middle Aged; Myocardial Infarction; Oxprenolol; Patient Dropouts; Propanolamines; Substance Withdrawal Syndrome | 1981 |
Effects of treatment on circadian rhythms of blood pressure.
Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Circadian Rhythm; Heart Rate; Humans; Hypertension; Labetalol; Metoprolol; Oxprenolol | 1981 |
[Clinical value of selective beta 1 block in antihypertensive therapy].
Topics: Adult; Atenolol; Female; Humans; Hypertension; Male; Oxprenolol; Pindolol; Propanolamines | 1981 |
Retroperitoneal fibrosis associated with atenolol.
Topics: Atenolol; Blood Sedimentation; Humans; Oxprenolol; Practolol; Propanolamines; Retroperitoneal Fibrosis | 1980 |
Beta-blockers inhibit the modification of low-density lipoproteins by sodium hypochlorite in vitro.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Atenolol; Bepridil; Biphenyl Compounds; Chemical Phenomena; Chemistry; Cholesterol Esters; Diclofenac; Free Radicals; Humans; Lipoproteins, LDL; Macrophages; Molecular Structure; Oxprenolol; Particle Size; Picrates; Sodium Hypochlorite; Spectrum Analysis; Thiobarbituric Acid Reactive Substances | 1997 |
Relationship between amount of beta-blockers permeating through the stratum corneum and skin irritation after application of beta-blocker adhesive patches to guinea pig skin.
Topics: Acebutolol; Administration, Cutaneous; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Dermatitis, Irritant; Guinea Pigs; Male; Oxprenolol; Skin; Skin Absorption; Timolol | 1997 |
Evaluation of the immobilized artificial membrane phosphatidylcholine. Drug discovery column for high-performance liquid chromatographic screening of drug-membrane interactions.
Topics: Acebutolol; Acetonitriles; Adrenergic beta-Antagonists; Alprenolol; Aniline Compounds; Atenolol; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Membranes, Artificial; Metoprolol; Models, Chemical; Osmolar Concentration; Oxprenolol; Phosphatidylcholines; Pindolol; Propranolol; Reproducibility of Results; Timolol | 1998 |
In vitro permeability of eight beta-blockers through Caco-2 monolayers utilizing liquid chromatography/electrospray ionization mass spectrometry.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Atenolol; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Chromatography, Liquid; Epithelial Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Mass Spectrometry; Metoprolol; Molecular Structure; Oxprenolol; Pindolol; Propranolol; Research Design; Timolol | 1998 |
The interactivities with lipid membranes differentially characterize selective and nonselective beta1-blockers.
Topics: Adrenergic beta-Antagonists; Alprenolol; Anesthesia; Anesthetics; Atenolol; Biomimetics; Lipid Bilayers; Lipids; Liposomes; Membranes, Artificial; Metoprolol; Oxprenolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta | 2010 |