atenolol and methyldopa

atenolol has been researched along with methyldopa in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199020 (46.51)18.7374
1990's4 (9.30)18.2507
2000's7 (16.28)29.6817
2010's11 (25.58)24.3611
2020's1 (2.33)2.80

Authors

AuthorsStudies
Ax, F; Bonham, NM; Hallberg, A; Karlén, A; Lennernäs, H; Winiwarter, S1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Barritt, DW; Marshall, AJ; Roberts, CJ1
Bayliss, PF; Duncan, SM1
Barker, NP; Galloway, DB; Jeffers, TA; Petrie, JC; Webster, J1
Abdel-Mohsen, A; Scott, ME; Wilson, C1
Barker, NP; Basker, MA; Tweed, JA1
Okanga, JB1
Distler, A1
Ambrosioni, E; Costa, FV; Magelli, C; Magnani, B; Malini, PL2
Agosta, R; Ambrosioni, E; Costa, FV; Magnani, B1
Betts, TA; Clayton, AB; Harvey, PG1
Mason, B; Sleigh, R; Tweed, JA1
Blake, S; MacDonald, D1
Herlitz, H1
Betts, TA; Blake, A; Crowe, A; Harvey, P; Knight, R; Mortiboy, D1
Beevers, DG; Constantine, G; Luesley, DM; Reynolds, AL1
Guimarães, AC; Magalhães, LB1
Conway, J1
Fuerst, M1
Rubin, PC1
Latham, L; Lorimer, AR; McAreavey, D; McLaren, AD; Ramsey, LE; Reid, JL; Robertson, JI; Robertson, MP; Weir, RJ1
Brøns, M; Christensen, CK; Geday, E; Jacobsen, FK; Jensen, SN; Kristensen, BO; Linde, NC1
Currie, D; McDevitt, DG; Nicholson, AN; Wright, NA; Zetlein, MB1
Rollins, G1
Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V1

Reviews

4 review(s) available for atenolol and methyldopa

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[The sympathetic nervous system and essential hypertension].
    Medizinische Klinik, 1979, Nov-23, Volume: 74, Issue:47

    Topics: Atenolol; Catecholamines; Clonidine; Guanethidine; Humans; Hypertension; Methyldopa; Norepinephrine; Propranolol; Renin; Reserpine; Sympathetic Nervous System; Vanilmandelic Acid

1979
ACE-inhibitors and quality of life.
    Scandinavian journal of primary health care. Supplement, 1990, Volume: 1

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Captopril; Enalapril; Health Status; Humans; Hypertension; Methyldopa; Middle Aged; Oxprenolol; Quality of Life

1990
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
    American journal of obstetrics and gynecology, 2020, Volume: 223, Issue:4

    Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease; Female; Fetal Growth Retardation; Furosemide; Gestational Age; Humans; Hypertension; Incidence; Infant, Small for Gestational Age; Ketanserin; Methyldopa; Network Meta-Analysis; Nifedipine; Perinatal Death; Pindolol; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Premature Birth; Severity of Illness Index

2020

Trials

15 trial(s) available for atenolol and methyldopa

ArticleYear
The effects of atenolol (tenormin) and methyldopa on simple tests of central nervous function.
    British journal of clinical pharmacology, 1975, Volume: 2, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Brain; Clinical Trials as Topic; Flicker Fusion; Humans; Male; Methyldopa; Propanolamines; Pulse; Reaction Time; Sleep

1975
Atenolol, methyldopa, and chlorthalidone in moderate hypertension.
    British medical journal, 1977, Jan-08, Volume: 1, Issue:6053

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Chlorthalidone; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Propanolamines

1977
Atenolol and methyldopa in the treatment of hypertension.
    Postgraduate medical journal, 1977, Volume: 53 Suppl 3

    Topics: Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Methyldopa; Physical Exertion; Propanolamines

1977
A double-blind comparison of atenolol ('Tenormin') and methyldopa in the treatment of moderate hypertension in general practice: a multicentre study.
    Current medical research and opinion, 1977, Volume: 4, Issue:9

    Topics: Adult; Aged; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Propanolamines; Pulse

1977
Atenolol (Tenormin) compared with methyldopa (Aldomet) in the treatment of hypertension.
    East African medical journal, 1978, Volume: 55, Issue:9

    Topics: Adult; Aged; Atenolol; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Propanolamines

1978
[Comparison of the antihypertensive affectiveness of atenolol and methyldopa].
    Giornale di clinica medica, 1979, Volume: 60, Issue:8

    Topics: Adult; Aged; Atenolol; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Propanolamines

1979
[Comparison of exercise tolerance in hypertensive patients treated with atenolol and methyldopa].
    Giornale di clinica medica, 1979, Volume: 60, Issue:8

    Topics: Adult; Atenolol; Blood Pressure; Clinical Trials as Topic; Exercise Test; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Middle Aged; Oxygen Consumption; Physical Exertion; Propanolamines

1979
The effects of four antihypertensive agents on the Stroop colour-word test in normal male volunteer subjects.
    Psychopharmacology, 1977, Oct-20, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Antihypertensive Agents; Atenolol; Clinical Trials as Topic; Color Perception; Double-Blind Method; Humans; Male; Methyldopa; Personality; Personality Tests; Propranolol; Reading; Reserpine; Speech

1977
The prevention of the maternal manifestations of pre-eclampsia by intensive antihypertensive treatment.
    British journal of obstetrics and gynaecology, 1991, Volume: 98, Issue:3

    Topics: Adult; Atenolol; Bendroflumethiazide; Birth Weight; Drug Therapy, Combination; Embryonic and Fetal Development; Female; Fetal Death; Humans; Hypertension; Infant, Newborn; Methyldopa; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Proteinuria

1991
[Alphamethyldopa vs. atenolol in the treatment of arterial hypertension].
    Arquivos brasileiros de cardiologia, 1986, Volume: 46, Issue:6

    Topics: Adult; Aged; Atenolol; Blood Pressure; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged

1986
Third-line therapy. A cautionary note.
    Clinical and experimental hypertension. Part A, Theory and practice, 1985, Volume: 7, Issue:10

    Topics: Atenolol; Bendroflumethiazide; Captopril; Chlorthalidone; Female; Humans; Hypertension; Male; Methyldopa; Nifedipine

1985
Beta-blockers may have role in preeclampsia.
    JAMA, 1982, Aug-06, Volume: 248, Issue:5

    Topics: Adrenergic beta-Antagonists; Atenolol; Birth Weight; Clinical Trials as Topic; Female; Humans; Hypertension; Infant, Newborn; Methyldopa; Pre-Eclampsia; Pregnancy; Propranolol

1982
"Third drug" trial: comparative study of antihypertensive agents added to treatment when blood pressure remains uncontrolled by a beta blocker plus thiazide diuretic.
    British medical journal (Clinical research ed.), 1984, Jan-14, Volume: 288, Issue:6411

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Labetalol; Male; Methyldopa; Middle Aged; Minoxidil; Prazosin

1984
Antihypertensive effect of atenolol (100 mg once a day) and methyldopa (250 mg thrice a day). A double-blind cross-over multicentre study.
    Acta medica Scandinavica, 1981, Volume: 209, Issue:4

    Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Methyldopa; Middle Aged; Propanolamines

1981
Central effects of repeated administration of atenolol and captopril in healthy volunteers.
    European journal of clinical pharmacology, 1994, Volume: 46, Issue:1

    Topics: Adult; Atenolol; Attention; Blood Pressure; Captopril; Central Nervous System; Electroencephalography; Flicker Fusion; Heart Rate; Humans; Male; Memory, Short-Term; Mental Recall; Methyldopa; Oxazepam; Psychomotor Performance; Reaction Time

1994

Other Studies

24 other study(ies) available for atenolol and methyldopa

ArticleYear
Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach.
    Journal of medicinal chemistry, 1998, Dec-03, Volume: 41, Issue:25

    Topics: Humans; Intestinal Absorption; Jejunum; Models, Biological; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship

1998
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Raynaud's phenomenon as side effect of beta-blockers in hypertension.
    British medical journal, 1976, Jun-19, Volume: 1, Issue:6024

    Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Oxprenolol; Propranolol; Raynaud Disease; Skin Temperature

1976
Multicentre general practitioner assessment of 'Tenormin' and methyldopa.
    The Journal of international medical research, 1979, Volume: 7, Issue:4

    Topics: Adult; Aged; Atenolol; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Propanolamines

1979
Effect of beta-blockers on psychomotor performance in normal volunteers.
    European journal of clinical pharmacology, 1985, Volume: 28 Suppl

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Anxiety; Arousal; Atenolol; Diazepam; Drug Interactions; Electroencephalography; Emotions; Evoked Potentials; False Positive Reactions; Female; Health Planning; Humans; Kinetics; Male; Methyldopa; Metoprolol; Propranolol; Psychometrics; Psychomotor Performance; Reaction Time; Reference Values; Reserpine; Time Factors; Visual Acuity

1985
Nifedipine as a second line antihypertensive drug in pregnancy.
    British journal of obstetrics and gynaecology, 1987, Volume: 94, Issue:12

    Topics: Adult; Atenolol; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Hypertension; Methyldopa; Nifedipine; Pregnancy; Pregnancy Complications, Cardiovascular

1987
Beta blockers in pregnancy.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1984, Volume: 169

    Topics: Adrenergic beta-Antagonists; Atenolol; Female; Humans; Hypertension; Kinetics; Methyldopa; Oxprenolol; Pregnancy; Pregnancy Complications, Cardiovascular

1984
Comparison of antihypertensive activity of atenolol and methyldopa at rest and during exercise.
    International journal of clinical pharmacology, therapy, and toxicology, 1981, Volume: 19, Issue:10

    Topics: Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Male; Methyldopa; Middle Aged; Physical Exertion; Propanolamines; Rest

1981
Guidelines on high blood pressure in pregnancy give new classifications of disease.
    Report on medical guidelines & outcomes research, 2000, Dec-18, Volume: 11, Issue:24

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Contraindications; Female; Humans; Hypertension; Labetalol; Methyldopa; Practice Guidelines as Topic; Pre-Eclampsia; Pregnancy; United States

2000