atenolol and mannitol

atenolol has been researched along with mannitol in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (21.43)18.2507
2000's14 (50.00)29.6817
2010's8 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghuloum, AM; Jain, AN; Sage, CR1
Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S1
Ertl, P; Rohde, B; Selzer, P1
Artursson, P; Luthman, K; Norinder, U; Stenberg, P1
Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S1
Caron, G; Ermondi, G1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Chatterjee, J; Gilon, C; Hoffman, A; Kessler, H; Marinelli, L; Ovadia, O; Zahn, G1
Faier, A; Gabinet, Y; Gilon, C; Halbfinger, E; Haskell-Luevano, C; Hess, S; Hoffman, A; Lapidot, T; Linde, Y; Ovadia, O; Portillo, FP; Safrai, E; Shalev, DE; Swed, A; Winkler, I; Xiang, Z; Yarden, D1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kapas, M; Kim, M; Riley, SA; Rowland, M; Sutcliffe, F; Turnberg, LA1
Agon, P; Goethals, P; Kaufman, JM; Van Haver, D1
Breimer, DD; Danhof, M; de Boer, AG; de Lange, EC; Hesselink, MB1
Ayrton, J; Collett, A; He, YL; Rowland, M; Sims, E; Walker, D; Warhurst, G1
Barsuhn, CL; Borchardt, RT; Ho, NF; Knipp, GT1
Amidon, GL; Hilgendorf, C; Langguth, P; Lipka, E; Regårdh, CG; Spahn-Langguth, H1
Crespi, CL; Fox, L; Hu, M; Steimel, DT; Stocker, P1
Denet, AR; Préat, V; Ucakar, B1
Guarve, K; Gupta, GD1
Grossouw, D; Krul, CA; van de Steeg, E; Verwei, M; Westerhout, J; Wortelboer, HM; Zeijdner, EE1

Reviews

1 review(s) available for atenolol and mannitol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

27 other study(ies) available for atenolol and mannitol

ArticleYear
Molecular hashkeys: a novel method for molecular characterization and its application for predicting important pharmaceutical properties of molecules.
    Journal of medicinal chemistry, 1999, May-20, Volume: 42, Issue:10

    Topics: Drug Design; Intestinal Absorption; Models, Molecular; Pharmaceutical Preparations; Structure-Activity Relationship

1999
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance

2000
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties.
    Journal of medicinal chemistry, 2000, Oct-05, Volume: 43, Issue:20

    Topics: Biological Availability; Biological Transport; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results

2000
Experimental and computational screening models for the prediction of intestinal drug absorption.
    Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12

    Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil

2001
Exploring the role of different drug transport routes in permeability screening.
    Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2

    Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics

2005
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Multiple N-methylation by a designed approach enhances receptor selectivity.
    Journal of medicinal chemistry, 2007, Nov-29, Volume: 50, Issue:24

    Topics: Binding Sites; Drug Design; Integrin alpha5beta1; Integrin alphaVbeta3; Ligands; Methylation; Models, Molecular; Molecular Conformation; Oligopeptides; Peptides, Cyclic; Platelet Glycoprotein GPIIb-IIIa Complex; Structure-Activity Relationship

2007
Backbone cyclic peptidomimetic melanocortin-4 receptor agonist as a novel orally administrated drug lead for treating obesity.
    Journal of medicinal chemistry, 2008, Feb-28, Volume: 51, Issue:4

    Topics: Administration, Oral; Animals; Anti-Obesity Agents; Biological Availability; Brain; Cell Line; Humans; Injections, Intravenous; Intestinal Absorption; Ligands; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Mimicry; Peptides, Cyclic; Rats; Rats, Wistar; Receptor, Melanocortin, Type 4; Structure-Activity Relationship; Tissue Distribution

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Effects of a non-absorbable osmotic load on drug absorption in healthy volunteers.
    British journal of clinical pharmacology, 1992, Volume: 34, Issue:1

    Topics: Adult; Atenolol; Furosemide; Gastrointestinal Transit; Humans; Hydrochlorothiazide; Intestinal Absorption; Mannitol; Osmosis; Salicylates; Salicylic Acid

1992
Permeability of the blood-brain barrier for atenolol studied by positron emission tomography.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:8

    Topics: Animals; Atenolol; Blood-Brain Barrier; Cell Membrane Permeability; Dogs; Injections, Intravenous; Mannitol; Tomography, Emission-Computed

1991
The use of intracerebral microdialysis to determine changes in blood-brain barrier transport characteristics.
    Pharmaceutical research, 1995, Volume: 12, Issue:1

    Topics: Animals; Atenolol; Blood-Brain Barrier; Brain; Brain Chemistry; Circadian Rhythm; Dialysis; Extracellular Space; Male; Mannitol; Osmolar Concentration; Rats; Rats, Wistar

1995
Comparison of HT29-18-C1 and Caco-2 cell lines as models for studying intestinal paracellular drug absorption.
    Pharmaceutical research, 1996, Volume: 13, Issue:2

    Topics: Atenolol; Biological Transport; Caco-2 Cells; Cell Division; Cell Membrane Permeability; Cimetidine; HT29 Cells; Humans; Hydrochlorothiazide; Intestinal Absorption; Mannitol; Ranitidine; Tritium

1996
Paracellular diffusion in Caco-2 cell monolayers: effect of perturbation on the transport of hydrophilic compounds that vary in charge and size.
    Journal of pharmaceutical sciences, 1997, Volume: 86, Issue:10

    Topics: Atenolol; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chelating Agents; Chemical Phenomena; Chemistry, Physical; Diffusion; Drug Interactions; Egtazic Acid; Formates; Humans; Lactic Acid; Mannitol; Methylamines; Palmitoylcarnitine; Solutions; Structure-Activity Relationship; Tight Junctions; Urea

1997
Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transport.
    Journal of pharmaceutical sciences, 2000, Volume: 89, Issue:1

    Topics: Antipyrine; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Caco-2 Cells; Carrier Proteins; Cell Membrane Permeability; Cellular Senescence; Coculture Techniques; Furosemide; HT29 Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Ketoprofen; Mannitol; Metoprolol; Microscopy, Electron; Piroxicam; Reproducibility of Results; Terbutaline

2000
Analysis of drug transport and metabolism in cell monolayer systems that have been modified by cytochrome P4503A4 cDNA-expression.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000, Volume: 12, Issue:1

    Topics: Animals; Atenolol; Biological Transport; Cell Line; Cell Membrane Permeability; Cimetidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA, Complementary; Erythromycin; Glucose; Humans; Mammals; Mannitol; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenylalanine; Propranolol; Recombinant Proteins; Testosterone; Tumor Cells, Cultured; Verapamil

2000
Transdermal delivery of timolol and atenolol using electroporation and iontophoresis in combination: a mechanistic approach.
    Pharmaceutical research, 2003, Volume: 20, Issue:12

    Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Atenolol; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Electrochemistry; Electroporation; Humans; In Vitro Techniques; Iontophoresis; Lipids; Mannitol; Osmosis; Spectrophotometry, Ultraviolet; Timolol

2003
Formulation and evaluation of extended release asymmetric membrane capsules of atenolol.
    Current drug delivery, 2011, Volume: 8, Issue:2

    Topics: Atenolol; Capsules; Cardiovascular Agents; Cellulose; Citric Acid; Delayed-Action Preparations; Diffusion; Drug Compounding; Drug Delivery Systems; Excipients; Hydrogen-Ion Concentration; Hypromellose Derivatives; Kinetics; Mannitol; Methylcellulose; Microscopy, Electron, Scanning; Solubility; Surface Properties; Viscosity

2011
A new approach to predict human intestinal absorption using porcine intestinal tissue and biorelevant matrices.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2014, Oct-15, Volume: 63

    Topics: Animals; Atenolol; Caco-2 Cells; Cimetidine; HT29 Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Jejunum; Mannitol; Permeability; Ranitidine; Swine; Tumor Cells, Cultured

2014