atenolol has been researched along with clonidine in 66 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (25.76) | 18.7374 |
| 1990's | 16 (24.24) | 18.2507 |
| 2000's | 18 (27.27) | 29.6817 |
| 2010's | 14 (21.21) | 24.3611 |
| 2020's | 1 (1.52) | 2.80 |
| Authors | Studies |
|---|---|
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Andrisano, V; Barril, X; Bartolini, M; Carreiras, Mdo C; de los Ríos, C; García, AG; Huertas, O; León, R; López, B; López, MG; Luque, FJ; Marco-Contelles, J; Rodríguez-Franco, MI; Samadi, A; Villarroya, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, J; Chen, X; Huang, L; Li, X; Sun, Y | 1 |
| Huang, L; Li, X; Meng, F; Miao, H; Sun, Y | 1 |
| Chang, S; Gao, W; Gao, YX; Liao, H; Pang, T; Qiu, WW; Wang, YJ; Wang, YY; Xu, Y; Xu, YZ; Yang, LF; Yu, LG; Zhang, LY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Guo, QL; Huang, SL; Huang, ZS; Li, D; Liu, ZQ; Ou, TM; Tan, JH; Wang, HG; Wang, N; Wu, JQ; Xia, CL | 1 |
| An, B; Hu, J; Huang, L; Li, X; Li, Z; Pan, T | 1 |
| Chen, H; Ding, H; Gao, Y; Jiang, X; Liu, W; Liu, X; Tian, L; Xu, Z; Zhao, Q | 1 |
| Distler, A | 1 |
| Niedermayer, W; Seiler, KU; Wassermann, O | 1 |
| Blatteis, CM; Quan, N; Ungar, AL; Xin, L | 1 |
| Andreasen, M; Lambert, JD | 1 |
| Chee, KY; Sachdev, P | 1 |
| Bradley, CA; Burger, C; Hays, JT; Houston, MC; Nadeau, J; Olafsson, L; Swift, L | 1 |
| Deering, AH; Harron, DW; McMahon, M; Scott, M; Shanks, RG | 1 |
| Davidman, M; Davies, SF; Graif, JL; Husebye, DG; Iber, C; Maddy, MM; McArthur, CD; O'Connell, MB; Path, MJ | 1 |
| Julius, S; Sekkarie, MA; Takiyyuddin, M; Weder, AB | 1 |
| Goshima, Y; Kubo, T; Misu, Y | 1 |
| Yuwiler, A | 1 |
| Goldstein, DS; Turkkan, JS | 1 |
| Bovenzi, F; Contursi, V; Loiacono, N; Maiorano, G; Petrelli, G; Ricapito, M | 1 |
| Cimmino, G; Iannuzzi, G; La Vecchia, M; Novelli Genuino, G; Saulino, C; Simonetti, A; Valerio, V; Vergara, G | 1 |
| Ikäheimo, M; Jounela, AJ; Lilja, M; Mattila, MJ | 1 |
| Campbell, BC; Reid, JL | 1 |
| Athias, P; Ettaiche, M; Klepping, J; Variot, N | 1 |
| Jounela, AJ; Juustila, H; Lilja, M; Mattila, MJ | 1 |
| Jounela, AJ; Juustila, HJ; Lilja, M; Paalzow, L | 1 |
| Hilakivi, I | 1 |
| Kitada, Y; Kosasa, T; Miyauchi, T; Satoh, S | 1 |
| Elliott, HL; MacPhee, G; Panfilov, V; Reid, JL | 1 |
| Anconina, J; Atlas, P; Cherrier, F; Danchin, N; Genton, P; Leclere, J | 1 |
| Ambrosio, GB; Casiglia, E; Colangeli, G; Di Menza, G; Ginocchio, G; Mazza, A; Onesto, C; Pegoraro, L; Spolaore, P | 1 |
| Ballet, A; Ector, H; Heidbüchel, H; Tack, J; Van de Werf, F; Vanneste, L | 1 |
| Brzostek, T; Collen, D; Heidbüchel, H; Janssens, L; Lesaffre, E; Mortelmans, L; Scheys, I; Van de Werf, F; Wackers, FJ; Willems, GM | 1 |
| Shi, CZ; Zhuang, LZ | 1 |
| Cushman, WC; Freis, ED; Fye, C; Gottdiener, J; Hamburger, RJ; Kochar, MS; Lakshman, R; Massie, BM; Materson, BJ; Reda, DJ | 1 |
| Grigioni, M; Marano, G; Tiburzi, F; Vergari, A; Zanghi, F | 1 |
| Anderson, RJ; Gottdiener, JS; Massie, BM; Materson, BJ; Reda, DJ; Williams, DW | 1 |
| Cushman, WC; Freis, ED; Lakshman, MR; Materson, BJ; Reda, DJ | 1 |
| Capecchi, PL; Colafati, M; Di Perri, T; Pasini, FL; Puccetti, L; Randisi, P | 1 |
| Robles, NR | 1 |
| Lelieveld, H; Nieveen, M; Ponce, MC; Steffens, A; van den Thillart, G; Van Raaij, M; Vianen, G; Zaagsma, J | 1 |
| Cushman, WC; Materson, BJ; Reda, DJ; Williams, DW | 1 |
| Gokee, A; Rocchini, AP; Yang, JQ | 1 |
| Christensen, LP; Dedkov, EI; Tomanek, RJ; Weiss, RM | 1 |
| Christian, R; Colon, PJ; Cushman, WC; Einhorn, PT; Ford, CE; Goff, DC; Henriquez, MA; Margolis, KL; Piller, LB; Vidt, DG; Wong, ND; Wright, JT | 1 |
| Cividjian, A; Quintin, L; Toader, E | 1 |
| Friedman, GD; Habel, LA; Udaltsova, N | 1 |
| Cheng, YQ; Lin, LL; Liu, AJ; Su, DF; Wang, D; Wang, W | 1 |
| Harrison, JC; Kerr, DS; Read, MI; Sammut, IA | 1 |
4 review(s) available for atenolol and clonidine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[The sympathetic nervous system and essential hypertension].
Topics: Atenolol; Catecholamines; Clonidine; Guanethidine; Humans; Hypertension; Methyldopa; Norepinephrine; Propranolol; Renin; Reserpine; Sympathetic Nervous System; Vanilmandelic Acid | 1979 |
Behaviour and hypertension: a pathophysiological puzzle.
Topics: Arousal; Atenolol; Autonomic Nervous System; Blood Pressure; Clonidine; Humans; Hypertension; Muscle, Smooth, Vascular; Receptors, Adrenergic, beta | 1989 |
Clinical pharmacology of drugs acting on imidazoline and adrenergic receptors. Studies with clonidine, moxonidine, rilmenidine, and atenolol.
Topics: Antihypertensive Agents; Atenolol; Clinical Trials as Topic; Clonidine; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Oxazoles; Placebos; Receptors, Adrenergic; Receptors, Drug; Reference Values; Rilmenidine | 1995 |
15 trial(s) available for atenolol and clonidine
| Article | Year |
|---|---|
Pharmacological characterization of tardive akathisia.
Topics: Administration, Oral; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Arousal; Atenolol; Benztropine; Brain; Bromocriptine; Chronic Disease; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Dyskinesia, Drug-Induced; Humans; Infusions, Intravenous; Male; Metoclopramide; Metoprolol; Physostigmine; Propranolol; Psychomotor Agitation; Schizophrenia, Paranoid | 1990 |
The effects of clonidine hydrochloride versus atenolol monotherapy on serum lipids, lipid subfractions, and apolipoproteins in mild hypertension.
Topics: Adolescent; Adult; Apolipoproteins; Atenolol; Cholesterol; Clonidine; Double-Blind Method; Humans; Hypertension; Lipoproteins; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Triglycerides | 1990 |
Effect of the combination of alinidine and other anti-anginal drugs on heart rate and blood pressure in healthy volunteers.
Topics: Adult; Angina Pectoris; Atenolol; Blood Pressure; Clonidine; Double-Blind Method; Drug Evaluation; Drug Interactions; Heart Rate; Humans; Male; Nifedipine; Nitroglycerin; Posture | 1989 |
Comparative effects of transdermal clonidine and oral atenolol on acute exercise performance and response to aerobic conditioning in subjects with hypertension.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Atenolol; Clonidine; Dermatitis, Contact; Double-Blind Method; Drug Eruptions; Exercise; Headache; Heart Rate; Humans; Hypertension; Male; Random Allocation; Weight Loss | 1989 |
Haemodynamic effects of prazosin combinations during dynamic and isometric exercise.
Topics: Adult; Atenolol; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Electrocardiography; Female; Hemodynamics; Humans; Hypertension; Isometric Contraction; Male; Middle Aged; Physical Exertion; Prazosin | 1985 |
Interaction of clonidine and beta-blockers.
Topics: Adrenergic beta-Antagonists; Adult; Animals; Atenolol; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prazosin; Propranolol; Rabbits; Sotalol | 1980 |
Comparative effects of atenolol and clonidine on polygraphically recorded sleep in hypertensive men: a randomized, double-blind, crossover study.
Topics: Adolescent; Adult; Atenolol; Blood Pressure; Clonidine; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Male; Middle Aged; Sleep | 1995 |
Effect of two different therapeutic approaches on total and cardiovascular mortality in a Cardiovascular Study in the Elderly (CASTEL).
Topics: Aged; Aged, 80 and over; Atenolol; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Heart Diseases; Humans; Hypertension; Italy; Male; Nifedipine; Prospective Studies; Survival Analysis | 1994 |
Significance of arrhythmias during the first 24 hours of acute myocardial infarction treated with alteplase and effect of early administration of a beta-blocker or a bradycardiac agent on their incidence.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atenolol; Clonidine; Double-Blind Method; Electrocardiography, Ambulatory; Female; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Prognosis; Prospective Studies; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator | 1994 |
Short-term effects of early intravenous treatment with a beta-adrenergic blocking agent or a specific bradycardiac agent in patients with acute myocardial infarction receiving thrombolytic therapy.
Topics: Adult; Aged; Arrhythmias, Cardiac; Atenolol; Cardiovascular Agents; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Exercise Test; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome; Vascular Patency; Ventricular Function, Left | 1993 |
Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Age Factors; Aged; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Captopril; Clonidine; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin | 1993 |
Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Captopril; Clonidine; Cohort Studies; Diltiazem; Diuretics; Double-Blind Method; Echocardiography; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardium; Organ Size; Prazosin; Prevalence; Risk Factors; Sodium Chloride Symporter Inhibitors; Treatment Outcome; United States; United States Department of Veterans Affairs | 1997 |
Diuretics and beta-blockers do not have adverse effects at 1 year on plasma lipid and lipoprotein profiles in men with hypertension. Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Captopril; Clonidine; Diltiazem; Diuretics; Double-Blind Method; Hospitals, Veterans; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Potassium; Prazosin; Time Factors; Treatment Outcome; United States | 1999 |
Pulse pressure changes with six classes of antihypertensive agents in a randomized, controlled trial.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Clonidine; Diastole; Diltiazem; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Pressure; Pulse; Randomized Controlled Trials as Topic; Systole; Time Factors; Treatment Outcome | 2001 |
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthalidone; Clonidine; Double-Blind Method; Doxazosin; Female; Heart Diseases; Hispanic or Latino; Humans; Hydralazine; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Middle Aged; Puerto Rico; Reserpine; Treatment Outcome; United States; United States Virgin Islands; White People | 2007 |
47 other study(ies) available for atenolol and clonidine
| Article | Year |
|---|---|
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytosol; Dihydropyridines; Humans; Hydrogen Peroxide; Kinetics; Ligands; Models, Molecular; Peptide Fragments; Permeability; Tacrine | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Inhibition of cholinesterase and monoamine oxidase-B activity by Tacrine-Homoisoflavonoid hybrids.
Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Cholinesterases; Electrophorus; Humans; Isoflavones; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Swine; Tacrine | 2013 |
Discovery of indanone derivatives as multi-target-directed ligands against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Humans; Indans; Inhibitory Concentration 50; Ligands; Peptide Fragments; Permeability; Protein Aggregates | 2014 |
Design, synthesis and biological evaluation of tricyclic diterpene derivatives as novel neuroprotective agents against ischemic brain injury.
Topics: Animals; Brain Injuries; Cell Survival; Diterpenes; Dose-Response Relationship, Drug; Drug Design; Glutamic Acid; Molecular Structure; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2015 |
Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Cell Death; Cell Line; Cholinesterase Inhibitors; Drug Design; Glutathione; Humans; Quinolines; Reactive Oxygen Species | 2017 |
Synthesis and evaluation of clioquinol-rolipram/roflumilast hybrids as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Aminopyridines; Animals; Benzamides; Clioquinol; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Drug Design; Humans; Ligands; Mice; Rats; Rolipram | 2019 |
Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Dyrk Kinases; Glycogen Synthase Kinase 3 beta; Harmine; Humans; Models, Molecular; Molecular Structure; Neuroprotective Agents; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Structure-Activity Relationship | 2021 |
Pharmacokinetics of antihypertensive drugs (atenolol, metoprolol, propranolol and clonidine) and their metabolites during intermittent haemodialysis in humans.
Topics: Antihypertensive Agents; Atenolol; Clonidine; Humans; Kinetics; Propranolol; Renal Dialysis | 1978 |
Preoptic norepinephrine-induced hypothermia is mediated by alpha 2-adrenoceptors.
Topics: Animals; Atenolol; Body Temperature; Body Temperature Regulation; Clonidine; Dialysis; Dobutamine; Dose-Response Relationship, Drug; Guinea Pigs; Male; Norepinephrine; Practolol; Preoptic Area; Propranolol; Receptors, Adrenergic, alpha; Reference Values; Skin Temperature; Yohimbine | 1992 |
Noradrenaline receptors participate in the regulation of GABAergic inhibition in area CA1 of the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atenolol; Bicuculline; Clonidine; Dose-Response Relationship, Drug; Evoked Potentials; Female; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Norepinephrine; Propranolol; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, GABA-A; Synapses | 1991 |
Autoregulation of endogenous epinephrine release via presynaptic adrenoceptors in the rat hypothalamic slice.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Benzylamines; Butoxamine; Chromatography, High Pressure Liquid; Clonidine; Electric Stimulation; Epinephrine; Homeostasis; Hypothalamus; Isoproterenol; Male; Potassium Chloride; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Sulpiride; Yohimbine | 1985 |
Synergistic action of postsynaptic alpha-adrenergic receptor stimulation on vasoactive intestinal polypeptide-induced increases in pineal N-acetyltransferase activity.
Topics: Acetyltransferases; Adrenergic alpha-Agonists; Animals; Arylamine N-Acetyltransferase; Atenolol; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Male; Methoxamine; Phenoxybenzamine; Phentolamine; Phenylephrine; Pineal Gland; Prazosin; Propranolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine | 1987 |
Production and reversal of DOCA-salt hypertension in baboons.
Topics: Animals; Atenolol; Biofeedback, Psychology; Clonidine; Desoxycorticosterone; Disease Models, Animal; Diuretics; Hypertension; Male; Papio; Sodium Chloride | 1987 |
[Clinico-therapeutic evaluation of the hypertensive patient by the isometric exertion test].
Topics: Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Clonidine; Female; Humans; Hypertension; Isometric Contraction; Male; Metoprolol; Middle Aged; Muscle Contraction | 1986 |
[Comparative evaluation in the treatment of arterial hypertension between prolonged-action clonidine and atenolol].
Topics: Adult; Aged; Atenolol; Clonidine; Delayed-Action Preparations; Female; Humans; Hypertension; Male; Middle Aged; Random Allocation | 1985 |
Regimen for the control of blood pressure and symptoms during clonidine withdrawal.
Topics: Adult; Aged; Atenolol; Blood Pressure; Chlordiazepoxide; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Normetanephrine; Substance Withdrawal Syndrome; Time Factors; Vanilmandelic Acid | 1985 |
Characterization of postjunctional adrenoceptor subtypes in isolated rat myocardial cells in culture.
Topics: Action Potentials; Albuterol; Animals; Atenolol; Cells, Cultured; Clonidine; Heart; Heart Rate; Isoproterenol; Methoxamine; Myocardium; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic | 1985 |
Abrupt and gradual change from clonidine to beta blockers in hypertension.
Topics: Adrenergic beta-Antagonists; Atenolol; Clonidine; Drug Interactions; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Pilot Projects; Propanolamines; Substance Withdrawal Syndrome; Timolol | 1982 |
The role of beta- and alpha-adrenoceptors in the regulation of the stages of the sleep-waking cycle in the cat.
Topics: Albuterol; Animals; Atenolol; Cats; Clonidine; Male; Metoprolol; Phentolamine; Practolol; Prazosin; Prenalterol; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sleep Stages | 1983 |
Further studies on the suppressing effect of isoproterenol on the immobility-reducing action of desipramine in the forced swimming test.
Topics: Animals; Atenolol; Clonidine; Desipramine; Isoproterenol; Male; Motor Activity; Phenylephrine; Rats; Rats, Inbred Strains; Swimming; Yohimbine | 1983 |
Stimulatory effect of norepinephrine on progesterone production by human first trimester placenta explants in vitro.
Topics: Atenolol; Clonidine; Culture Media, Serum-Free; Cyclic AMP; Female; Gadolinium; Gonadotropin-Releasing Hormone; Humans; Nifedipine; Norepinephrine; Organ Culture Techniques; Prazosin; Pregnancy; Pregnancy Trimester, First; Progesterone; Stimulation, Chemical; Trophoblasts; Yohimbine | 1993 |
Effects of isoflurane on cardiovascular system and sympathovagal balance in New Zealand white rabbits.
Topics: Anesthetics, Inhalation; Animals; Atenolol; Baroreflex; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Isoflurane; Male; Norepinephrine; Rabbits; Sympathetic Nervous System; Tachycardia; Vagotomy; Vagus Nerve | 1996 |
Systemic adenosine increase during cold pressor test is dependent on sympathetic activation.
Topics: Adenosine; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Clonidine; Cold Temperature; Female; Heart Rate; Humans; Male; Norepinephrine; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-1; Sympathetic Nervous System; Theophylline; Vasoconstriction; Vasodilator Agents | 1999 |
[New central agents in the treatment of arterial hypertension].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Clonidine; Diabetes Complications; Humans; Hypertension; Imidazoles; Nifedipine; Oxazoles; Renin-Angiotensin System; Reserpine; Rilmenidine; Risk Factors; Sympathetic Nervous System; Vasodilator Agents | 1999 |
Differential role of adrenoceptors in control of plasma glucose and fatty acids in carp, Cyprinus carpio (L.).
Topics: Adrenergic Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Blood Glucose; Carps; Clonidine; Epinephrine; Fatty Acids, Nonesterified; Isoproterenol; Lactic Acid; Norepinephrine; Propanolamines; Receptors, Adrenergic, beta; Yohimbine | 2001 |
Hypertension and insulin resistance are not directly related in obese dogs.
Topics: Adrenergic beta-Antagonists; Animals; Aspirin; Atenolol; Blood Glucose; Clonidine; Diet, Sodium-Restricted; Dietary Fats; Dogs; Female; Furosemide; Hemodynamics; Hypertension; I-kappa B Kinase; Insulin; Insulin Resistance; Male; Models, Animal; Models, Biological; Obesity; Prazosin; Protein Serine-Threonine Kinases; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sympathetic Nervous System | 2004 |
Reduction of heart rate by chronic beta1-adrenoceptor blockade promotes growth of arterioles and preserves coronary perfusion reserve in postinfarcted heart.
Topics: Adrenergic beta-Antagonists; Animals; Arterioles; Atenolol; Cardiac Output; Clonidine; Coronary Vessels; Diastole; Heart Rate; Male; Myocardial Infarction; Myocardial Reperfusion; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Stroke Volume | 2005 |
Recruitment of cardiac parasympathetic activity: effects of clonidine on cardiac vagal motoneurones, pressure lability, and cardiac baroreflex slope in rats.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Baroreflex; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart; Male; Motor Neurons; Rats; Rats, Sprague-Dawley; Recruitment, Neurophysiological; Sympatholytics; Vagus Nerve | 2009 |
Norepinephrine antagonists and cancer risk.
Topics: Atenolol; Breast Neoplasms; Clonidine; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Male; Metoprolol; Neoplasms; Norepinephrine; Odds Ratio; Prazosin; Propranolol; Prostatic Neoplasms; Risk Assessment | 2011 |
Long-term treatment of clonidine, atenolol, amlodipine and dihydrochlorothiazide, but not enalapril, impairs the sexual function in male spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Atenolol; Clonidine; Drug Administration Schedule; Enalapril; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Inbred SHR; Sexual Dysfunction, Physiological | 2015 |
Atenolol offers better protection than clonidine against cardiac injury in kainic acid-induced status epilepticus.
Topics: Animals; Atenolol; Behavior, Animal; Cardiotonic Agents; Clonidine; Electrocardiography; Electroencephalography; Heart Injuries; Heart Rate; Kainic Acid; Male; Myocardium; Rats, Sprague-Dawley; Status Epilepticus | 2015 |