atenolol and clonidine

atenolol has been researched along with clonidine in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-199017 (25.76)18.7374
1990's16 (24.24)18.2507
2000's18 (27.27)29.6817
2010's14 (21.21)24.3611
2020's1 (1.52)2.80

Authors

AuthorsStudies
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Andrisano, V; Barril, X; Bartolini, M; Carreiras, Mdo C; de los Ríos, C; García, AG; Huertas, O; León, R; López, B; López, MG; Luque, FJ; Marco-Contelles, J; Rodríguez-Franco, MI; Samadi, A; Villarroya, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, J; Chen, X; Huang, L; Li, X; Sun, Y1
Huang, L; Li, X; Meng, F; Miao, H; Sun, Y1
Chang, S; Gao, W; Gao, YX; Liao, H; Pang, T; Qiu, WW; Wang, YJ; Wang, YY; Xu, Y; Xu, YZ; Yang, LF; Yu, LG; Zhang, LY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Guo, QL; Huang, SL; Huang, ZS; Li, D; Liu, ZQ; Ou, TM; Tan, JH; Wang, HG; Wang, N; Wu, JQ; Xia, CL1
An, B; Hu, J; Huang, L; Li, X; Li, Z; Pan, T1
Chen, H; Ding, H; Gao, Y; Jiang, X; Liu, W; Liu, X; Tian, L; Xu, Z; Zhao, Q1
Distler, A1
Niedermayer, W; Seiler, KU; Wassermann, O1
Blatteis, CM; Quan, N; Ungar, AL; Xin, L1
Andreasen, M; Lambert, JD1
Chee, KY; Sachdev, P1
Bradley, CA; Burger, C; Hays, JT; Houston, MC; Nadeau, J; Olafsson, L; Swift, L1
Deering, AH; Harron, DW; McMahon, M; Scott, M; Shanks, RG1
Davidman, M; Davies, SF; Graif, JL; Husebye, DG; Iber, C; Maddy, MM; McArthur, CD; O'Connell, MB; Path, MJ1
Julius, S; Sekkarie, MA; Takiyyuddin, M; Weder, AB1
Goshima, Y; Kubo, T; Misu, Y1
Yuwiler, A1
Goldstein, DS; Turkkan, JS1
Bovenzi, F; Contursi, V; Loiacono, N; Maiorano, G; Petrelli, G; Ricapito, M1
Cimmino, G; Iannuzzi, G; La Vecchia, M; Novelli Genuino, G; Saulino, C; Simonetti, A; Valerio, V; Vergara, G1
Ikäheimo, M; Jounela, AJ; Lilja, M; Mattila, MJ1
Campbell, BC; Reid, JL1
Athias, P; Ettaiche, M; Klepping, J; Variot, N1
Jounela, AJ; Juustila, H; Lilja, M; Mattila, MJ1
Jounela, AJ; Juustila, HJ; Lilja, M; Paalzow, L1
Hilakivi, I1
Kitada, Y; Kosasa, T; Miyauchi, T; Satoh, S1
Elliott, HL; MacPhee, G; Panfilov, V; Reid, JL1
Anconina, J; Atlas, P; Cherrier, F; Danchin, N; Genton, P; Leclere, J1
Ambrosio, GB; Casiglia, E; Colangeli, G; Di Menza, G; Ginocchio, G; Mazza, A; Onesto, C; Pegoraro, L; Spolaore, P1
Ballet, A; Ector, H; Heidbüchel, H; Tack, J; Van de Werf, F; Vanneste, L1
Brzostek, T; Collen, D; Heidbüchel, H; Janssens, L; Lesaffre, E; Mortelmans, L; Scheys, I; Van de Werf, F; Wackers, FJ; Willems, GM1
Shi, CZ; Zhuang, LZ1
Cushman, WC; Freis, ED; Fye, C; Gottdiener, J; Hamburger, RJ; Kochar, MS; Lakshman, R; Massie, BM; Materson, BJ; Reda, DJ1
Grigioni, M; Marano, G; Tiburzi, F; Vergari, A; Zanghi, F1
Anderson, RJ; Gottdiener, JS; Massie, BM; Materson, BJ; Reda, DJ; Williams, DW1
Cushman, WC; Freis, ED; Lakshman, MR; Materson, BJ; Reda, DJ1
Capecchi, PL; Colafati, M; Di Perri, T; Pasini, FL; Puccetti, L; Randisi, P1
Robles, NR1
Lelieveld, H; Nieveen, M; Ponce, MC; Steffens, A; van den Thillart, G; Van Raaij, M; Vianen, G; Zaagsma, J1
Cushman, WC; Materson, BJ; Reda, DJ; Williams, DW1
Gokee, A; Rocchini, AP; Yang, JQ1
Christensen, LP; Dedkov, EI; Tomanek, RJ; Weiss, RM1
Christian, R; Colon, PJ; Cushman, WC; Einhorn, PT; Ford, CE; Goff, DC; Henriquez, MA; Margolis, KL; Piller, LB; Vidt, DG; Wong, ND; Wright, JT1
Cividjian, A; Quintin, L; Toader, E1
Friedman, GD; Habel, LA; Udaltsova, N1
Cheng, YQ; Lin, LL; Liu, AJ; Su, DF; Wang, D; Wang, W1
Harrison, JC; Kerr, DS; Read, MI; Sammut, IA1

Reviews

4 review(s) available for atenolol and clonidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[The sympathetic nervous system and essential hypertension].
    Medizinische Klinik, 1979, Nov-23, Volume: 74, Issue:47

    Topics: Atenolol; Catecholamines; Clonidine; Guanethidine; Humans; Hypertension; Methyldopa; Norepinephrine; Propranolol; Renin; Reserpine; Sympathetic Nervous System; Vanilmandelic Acid

1979
Behaviour and hypertension: a pathophysiological puzzle.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:1

    Topics: Arousal; Atenolol; Autonomic Nervous System; Blood Pressure; Clonidine; Humans; Hypertension; Muscle, Smooth, Vascular; Receptors, Adrenergic, beta

1989
Clinical pharmacology of drugs acting on imidazoline and adrenergic receptors. Studies with clonidine, moxonidine, rilmenidine, and atenolol.
    Annals of the New York Academy of Sciences, 1995, Jul-12, Volume: 763

    Topics: Antihypertensive Agents; Atenolol; Clinical Trials as Topic; Clonidine; Humans; Hypertension; Imidazoles; Imidazoline Receptors; Oxazoles; Placebos; Receptors, Adrenergic; Receptors, Drug; Reference Values; Rilmenidine

1995

Trials

15 trial(s) available for atenolol and clonidine

ArticleYear
Pharmacological characterization of tardive akathisia.
    Biological psychiatry, 1990, Nov-01, Volume: 28, Issue:9

    Topics: Administration, Oral; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Arousal; Atenolol; Benztropine; Brain; Bromocriptine; Chronic Disease; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Dyskinesia, Drug-Induced; Humans; Infusions, Intravenous; Male; Metoclopramide; Metoprolol; Physostigmine; Propranolol; Psychomotor Agitation; Schizophrenia, Paranoid

1990
The effects of clonidine hydrochloride versus atenolol monotherapy on serum lipids, lipid subfractions, and apolipoproteins in mild hypertension.
    American heart journal, 1990, Volume: 120, Issue:1

    Topics: Adolescent; Adult; Apolipoproteins; Atenolol; Cholesterol; Clonidine; Double-Blind Method; Humans; Hypertension; Lipoproteins; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Triglycerides

1990
Effect of the combination of alinidine and other anti-anginal drugs on heart rate and blood pressure in healthy volunteers.
    British journal of clinical pharmacology, 1989, Volume: 27, Issue:1

    Topics: Adult; Angina Pectoris; Atenolol; Blood Pressure; Clonidine; Double-Blind Method; Drug Evaluation; Drug Interactions; Heart Rate; Humans; Male; Nifedipine; Nitroglycerin; Posture

1989
Comparative effects of transdermal clonidine and oral atenolol on acute exercise performance and response to aerobic conditioning in subjects with hypertension.
    Archives of internal medicine, 1989, Volume: 149, Issue:7

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Atenolol; Clonidine; Dermatitis, Contact; Double-Blind Method; Drug Eruptions; Exercise; Headache; Heart Rate; Humans; Hypertension; Male; Random Allocation; Weight Loss

1989
Haemodynamic effects of prazosin combinations during dynamic and isometric exercise.
    Annals of clinical research, 1985, Volume: 17, Issue:6

    Topics: Adult; Atenolol; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Electrocardiography; Female; Hemodynamics; Humans; Hypertension; Isometric Contraction; Male; Middle Aged; Physical Exertion; Prazosin

1985
Interaction of clonidine and beta-blockers.
    Acta medica Scandinavica, 1980, Volume: 207, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Animals; Atenolol; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prazosin; Propranolol; Rabbits; Sotalol

1980
Comparative effects of atenolol and clonidine on polygraphically recorded sleep in hypertensive men: a randomized, double-blind, crossover study.
    International journal of clinical pharmacology and therapeutics, 1995, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Atenolol; Blood Pressure; Clonidine; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Male; Middle Aged; Sleep

1995
Effect of two different therapeutic approaches on total and cardiovascular mortality in a Cardiovascular Study in the Elderly (CASTEL).
    Japanese heart journal, 1994, Volume: 35, Issue:5

    Topics: Aged; Aged, 80 and over; Atenolol; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Heart Diseases; Humans; Hypertension; Italy; Male; Nifedipine; Prospective Studies; Survival Analysis

1994
Significance of arrhythmias during the first 24 hours of acute myocardial infarction treated with alteplase and effect of early administration of a beta-blocker or a bradycardiac agent on their incidence.
    Circulation, 1994, Volume: 89, Issue:3

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atenolol; Clonidine; Double-Blind Method; Electrocardiography, Ambulatory; Female; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Prognosis; Prospective Studies; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator

1994
Short-term effects of early intravenous treatment with a beta-adrenergic blocking agent or a specific bradycardiac agent in patients with acute myocardial infarction receiving thrombolytic therapy.
    Journal of the American College of Cardiology, 1993, Volume: 22, Issue:2

    Topics: Adult; Aged; Arrhythmias, Cardiac; Atenolol; Cardiovascular Agents; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Exercise Test; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome; Vascular Patency; Ventricular Function, Left

1993
Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
    The New England journal of medicine, 1993, Apr-01, Volume: 328, Issue:13

    Topics: Age Factors; Aged; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Captopril; Clonidine; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin

1993
Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
    Circulation, 1997, Apr-15, Volume: 95, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Captopril; Clonidine; Cohort Studies; Diltiazem; Diuretics; Double-Blind Method; Echocardiography; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardium; Organ Size; Prazosin; Prevalence; Risk Factors; Sodium Chloride Symporter Inhibitors; Treatment Outcome; United States; United States Department of Veterans Affairs

1997
Diuretics and beta-blockers do not have adverse effects at 1 year on plasma lipid and lipoprotein profiles in men with hypertension. Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
    Archives of internal medicine, 1999, Mar-22, Volume: 159, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Captopril; Clonidine; Diltiazem; Diuretics; Double-Blind Method; Hospitals, Veterans; Humans; Hydrochlorothiazide; Hypertension; Lipids; Lipoproteins; Male; Middle Aged; Potassium; Prazosin; Time Factors; Treatment Outcome; United States

1999
Pulse pressure changes with six classes of antihypertensive agents in a randomized, controlled trial.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Clonidine; Diastole; Diltiazem; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prazosin; Pressure; Pulse; Randomized Controlled Trials as Topic; Systole; Time Factors; Treatment Outcome

2001
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:5

    Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthalidone; Clonidine; Double-Blind Method; Doxazosin; Female; Heart Diseases; Hispanic or Latino; Humans; Hydralazine; Hypertension; Hypolipidemic Agents; Lisinopril; Male; Middle Aged; Puerto Rico; Reserpine; Treatment Outcome; United States; United States Virgin Islands; White People

2007

Other Studies

47 other study(ies) available for atenolol and clonidine

ArticleYear
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
    Journal of medicinal chemistry, 2009, May-14, Volume: 52, Issue:9

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytosol; Dihydropyridines; Humans; Hydrogen Peroxide; Kinetics; Ligands; Models, Molecular; Peptide Fragments; Permeability; Tacrine

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Inhibition of cholinesterase and monoamine oxidase-B activity by Tacrine-Homoisoflavonoid hybrids.
    Bioorganic & medicinal chemistry, 2013, Dec-01, Volume: 21, Issue:23

    Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Cholinesterases; Electrophorus; Humans; Isoflavones; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Swine; Tacrine

2013
Discovery of indanone derivatives as multi-target-directed ligands against Alzheimer's disease.
    European journal of medicinal chemistry, 2014, Nov-24, Volume: 87

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Humans; Indans; Inhibitory Concentration 50; Ligands; Peptide Fragments; Permeability; Protein Aggregates

2014
Design, synthesis and biological evaluation of tricyclic diterpene derivatives as novel neuroprotective agents against ischemic brain injury.
    European journal of medicinal chemistry, 2015, Oct-20, Volume: 103

    Topics: Animals; Brain Injuries; Cell Survival; Diterpenes; Dose-Response Relationship, Drug; Drug Design; Glutamic Acid; Molecular Structure; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

2015
Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer's disease treatment.
    European journal of medicinal chemistry, 2017, Apr-21, Volume: 130

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Cell Death; Cell Line; Cholinesterase Inhibitors; Drug Design; Glutathione; Humans; Quinolines; Reactive Oxygen Species

2017
Synthesis and evaluation of clioquinol-rolipram/roflumilast hybrids as multitarget-directed ligands for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2019, Feb-01, Volume: 163

    Topics: Alzheimer Disease; Aminopyridines; Animals; Benzamides; Clioquinol; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclopropanes; Drug Design; Humans; Ligands; Mice; Rats; Rolipram

2019
Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2021, Oct-15, Volume: 222

    Topics: Alzheimer Disease; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Dyrk Kinases; Glycogen Synthase Kinase 3 beta; Harmine; Humans; Models, Molecular; Molecular Structure; Neuroprotective Agents; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Structure-Activity Relationship

2021
Pharmacokinetics of antihypertensive drugs (atenolol, metoprolol, propranolol and clonidine) and their metabolites during intermittent haemodialysis in humans.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1978, Volume: 15

    Topics: Antihypertensive Agents; Atenolol; Clonidine; Humans; Kinetics; Propranolol; Renal Dialysis

1978
Preoptic norepinephrine-induced hypothermia is mediated by alpha 2-adrenoceptors.
    The American journal of physiology, 1992, Volume: 262, Issue:3 Pt 2

    Topics: Animals; Atenolol; Body Temperature; Body Temperature Regulation; Clonidine; Dialysis; Dobutamine; Dose-Response Relationship, Drug; Guinea Pigs; Male; Norepinephrine; Practolol; Preoptic Area; Propranolol; Receptors, Adrenergic, alpha; Reference Values; Skin Temperature; Yohimbine

1992
Noradrenaline receptors participate in the regulation of GABAergic inhibition in area CA1 of the rat hippocampus.
    The Journal of physiology, 1991, Volume: 439

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atenolol; Bicuculline; Clonidine; Dose-Response Relationship, Drug; Evoked Potentials; Female; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Norepinephrine; Propranolol; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, GABA-A; Synapses

1991
Autoregulation of endogenous epinephrine release via presynaptic adrenoceptors in the rat hypothalamic slice.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Benzylamines; Butoxamine; Chromatography, High Pressure Liquid; Clonidine; Electric Stimulation; Epinephrine; Homeostasis; Hypothalamus; Isoproterenol; Male; Potassium Chloride; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Sulpiride; Yohimbine

1985
Synergistic action of postsynaptic alpha-adrenergic receptor stimulation on vasoactive intestinal polypeptide-induced increases in pineal N-acetyltransferase activity.
    Journal of neurochemistry, 1987, Volume: 49, Issue:3

    Topics: Acetyltransferases; Adrenergic alpha-Agonists; Animals; Arylamine N-Acetyltransferase; Atenolol; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Male; Methoxamine; Phenoxybenzamine; Phentolamine; Phenylephrine; Pineal Gland; Prazosin; Propranolol; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine

1987
Production and reversal of DOCA-salt hypertension in baboons.
    Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:1

    Topics: Animals; Atenolol; Biofeedback, Psychology; Clonidine; Desoxycorticosterone; Disease Models, Animal; Diuretics; Hypertension; Male; Papio; Sodium Chloride

1987
[Clinico-therapeutic evaluation of the hypertensive patient by the isometric exertion test].
    Minerva cardioangiologica, 1986, Volume: 34, Issue:3

    Topics: Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Clonidine; Female; Humans; Hypertension; Isometric Contraction; Male; Metoprolol; Middle Aged; Muscle Contraction

1986
[Comparative evaluation in the treatment of arterial hypertension between prolonged-action clonidine and atenolol].
    La Clinica terapeutica, 1985, Dec-31, Volume: 115, Issue:6

    Topics: Adult; Aged; Atenolol; Clonidine; Delayed-Action Preparations; Female; Humans; Hypertension; Male; Middle Aged; Random Allocation

1985
Regimen for the control of blood pressure and symptoms during clonidine withdrawal.
    International journal of clinical pharmacology research, 1985, Volume: 5, Issue:4

    Topics: Adult; Aged; Atenolol; Blood Pressure; Chlordiazepoxide; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Normetanephrine; Substance Withdrawal Syndrome; Time Factors; Vanilmandelic Acid

1985
Characterization of postjunctional adrenoceptor subtypes in isolated rat myocardial cells in culture.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:10

    Topics: Action Potentials; Albuterol; Animals; Atenolol; Cells, Cultured; Clonidine; Heart; Heart Rate; Isoproterenol; Methoxamine; Myocardium; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic

1985
Abrupt and gradual change from clonidine to beta blockers in hypertension.
    Acta medica Scandinavica, 1982, Volume: 211, Issue:5

    Topics: Adrenergic beta-Antagonists; Atenolol; Clonidine; Drug Interactions; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Pilot Projects; Propanolamines; Substance Withdrawal Syndrome; Timolol

1982
The role of beta- and alpha-adrenoceptors in the regulation of the stages of the sleep-waking cycle in the cat.
    Brain research, 1983, Oct-24, Volume: 277, Issue:1

    Topics: Albuterol; Animals; Atenolol; Cats; Clonidine; Male; Metoprolol; Phentolamine; Practolol; Prazosin; Prenalterol; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sleep Stages

1983
Further studies on the suppressing effect of isoproterenol on the immobility-reducing action of desipramine in the forced swimming test.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:4

    Topics: Animals; Atenolol; Clonidine; Desipramine; Isoproterenol; Male; Motor Activity; Phenylephrine; Rats; Rats, Inbred Strains; Swimming; Yohimbine

1983
Stimulatory effect of norepinephrine on progesterone production by human first trimester placenta explants in vitro.
    Life sciences, 1993, Volume: 52, Issue:20

    Topics: Atenolol; Clonidine; Culture Media, Serum-Free; Cyclic AMP; Female; Gadolinium; Gonadotropin-Releasing Hormone; Humans; Nifedipine; Norepinephrine; Organ Culture Techniques; Prazosin; Pregnancy; Pregnancy Trimester, First; Progesterone; Stimulation, Chemical; Trophoblasts; Yohimbine

1993
Effects of isoflurane on cardiovascular system and sympathovagal balance in New Zealand white rabbits.
    Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Atenolol; Baroreflex; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Isoflurane; Male; Norepinephrine; Rabbits; Sympathetic Nervous System; Tachycardia; Vagotomy; Vagus Nerve

1996
Systemic adenosine increase during cold pressor test is dependent on sympathetic activation.
    Clinical and experimental pharmacology & physiology, 1999, Volume: 26, Issue:10

    Topics: Adenosine; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Clonidine; Cold Temperature; Female; Heart Rate; Humans; Male; Norepinephrine; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-1; Sympathetic Nervous System; Theophylline; Vasoconstriction; Vasodilator Agents

1999
[New central agents in the treatment of arterial hypertension].
    Anales de medicina interna (Madrid, Spain : 1984), 1999, Volume: 16, Issue:10

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Clonidine; Diabetes Complications; Humans; Hypertension; Imidazoles; Nifedipine; Oxazoles; Renin-Angiotensin System; Reserpine; Rilmenidine; Risk Factors; Sympathetic Nervous System; Vasodilator Agents

1999
Differential role of adrenoceptors in control of plasma glucose and fatty acids in carp, Cyprinus carpio (L.).
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:2

    Topics: Adrenergic Agonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Blood Glucose; Carps; Clonidine; Epinephrine; Fatty Acids, Nonesterified; Isoproterenol; Lactic Acid; Norepinephrine; Propanolamines; Receptors, Adrenergic, beta; Yohimbine

2001
Hypertension and insulin resistance are not directly related in obese dogs.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Aspirin; Atenolol; Blood Glucose; Clonidine; Diet, Sodium-Restricted; Dietary Fats; Dogs; Female; Furosemide; Hemodynamics; Hypertension; I-kappa B Kinase; Insulin; Insulin Resistance; Male; Models, Animal; Models, Biological; Obesity; Prazosin; Protein Serine-Threonine Kinases; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sympathetic Nervous System

2004
Reduction of heart rate by chronic beta1-adrenoceptor blockade promotes growth of arterioles and preserves coronary perfusion reserve in postinfarcted heart.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Arterioles; Atenolol; Cardiac Output; Clonidine; Coronary Vessels; Diastole; Heart Rate; Male; Myocardial Infarction; Myocardial Reperfusion; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Stroke Volume

2005
Recruitment of cardiac parasympathetic activity: effects of clonidine on cardiac vagal motoneurones, pressure lability, and cardiac baroreflex slope in rats.
    British journal of anaesthesia, 2009, Volume: 102, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Baroreflex; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart; Male; Motor Neurons; Rats; Rats, Sprague-Dawley; Recruitment, Neurophysiological; Sympatholytics; Vagus Nerve

2009
Norepinephrine antagonists and cancer risk.
    International journal of cancer, 2011, Feb-01, Volume: 128, Issue:3

    Topics: Atenolol; Breast Neoplasms; Clonidine; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Male; Metoprolol; Neoplasms; Norepinephrine; Odds Ratio; Prazosin; Propranolol; Prostatic Neoplasms; Risk Assessment

2011
Long-term treatment of clonidine, atenolol, amlodipine and dihydrochlorothiazide, but not enalapril, impairs the sexual function in male spontaneously hypertensive rats.
    PloS one, 2015, Volume: 10, Issue:1

    Topics: Animals; Antihypertensive Agents; Atenolol; Clonidine; Drug Administration Schedule; Enalapril; Hydrochlorothiazide; Hypertension; Male; Rats; Rats, Inbred SHR; Sexual Dysfunction, Physiological

2015
Atenolol offers better protection than clonidine against cardiac injury in kainic acid-induced status epilepticus.
    British journal of pharmacology, 2015, Volume: 172, Issue:19

    Topics: Animals; Atenolol; Behavior, Animal; Cardiotonic Agents; Clonidine; Electrocardiography; Electroencephalography; Heart Injuries; Heart Rate; Kainic Acid; Male; Myocardium; Rats, Sprague-Dawley; Status Epilepticus

2015