atenolol and aspirin

atenolol has been researched along with aspirin in 76 studies

Research

Studies (76)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (6.58)	18.7374
1990's	14 (18.42)	18.2507
2000's	29 (38.16)	29.6817
2010's	24 (31.58)	24.3611
2020's	4 (5.26)	2.80

Authors

Authors	Studies
Gubernator, K; Kansy, M; Senner, F	1
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Balliano, TL; Barbosa, G; Carvalho, VF; da Silva, BA; de Souza, ET; Lima, LM; Martins, IRR; Martins, MA; Medeiros, MM; Moraes Junior, MO; Nunes, IKDC; Silva, PMR; Silva, SWD	1
Algra, A; Kappelle, LJ; Koudstaal, PJ; Pop, GA; van Gijn, J; van Latum, JC	1
Commerford, PJ; Gordon, GD; Green, BK; Horak, AR; Millar, RN	1
Bellotti, P; Chiarella, F; Domenicucci, S; Lupi, G; Vecchio, C	1
Therkelsen, K; Toft, E; Vyberg, M	1
Frericks, H	1
Takens, H	1
Neuvonen, PJ; Olkkola, KT	1
Axthelm, T; Kirch, W; Köhler, H; Mutschler, E; Schäfer-Korting, M	1
Algra, A; Kappelle, LJ; Koudstaal, PJ; van Gijn, J; van Latum, JC; van Swieten, JC	1
Haring, P; Hietakorpi, S; Koski, E; Nuutinen, LS; Purhonen, S; Söderlin, MK	1
Algra, A; Herderscheê, D; Hijdra, A; Kappelle, LJ; Koudstaal, PJ; van Gijn, J	1
Kennedy, C	1
Algra, A; Cillessen, JP; Kappelle, LJ; van Gijn, J; van Swieten, JC	1
Bashour, TT; Blumenthal, J; Espinosa, E; Mason, DT; Wong, T	1
Bacon, NC	1
Cavalli, A; Negri, E; Santoro, L; Volpi, A	1
Berry, DC; de Rosis, F; Grasso, F	1
Bednar, MM; Ellenberger, C; Gross, CE; Howard, DB; Russell, SR	1
Doskina, EV	1
Ito, MK; Pieper, JA; Talbert, RL	1
Fitilev, SB; Lepakhin, VK; Levin, AM; Oganov, RG; Sytchev, EN; Titarova, YY	1
Diener, HC	1
Howard, SC; Rothwell, PM	1
Anesini, C; Borda, E; Coussio, J; Ferraro, G; Turner, S	1
Gokee, A; Rocchini, AP; Yang, JQ	1
Dahlöf, B; de Faire, U; Devereux, RB; Edelman, JM; Fossum, E; Fyhrquist, F; Ibsen, H; Julius, S; Kjeldsen, SE; Kristianson, K; Lederballe-Pedersen, O; Lindholm, LH; Moan, A; Nieminen, MS; Omvik, P; Oparil, S; Snapinn, SM; Wedel, H	1
Ahmed, SU; Khairuzzaman, A; Patel, NK; Savva, M	1
Yu, L; Zeng, S	1
Alves, DP; Caliendo, G; de Nucci, G; Donato, JL; Fiorino, F; Lavecchia, A; Lilla, S; Mendes, GD; Montes-Gil, AC; Okuyama, CE; Perissutti, E; Priviero, FB; Santagada, V; Severino, B; Zanfolin, M	1
Kumar, V; Shah, RP; Singh, S	1
Kumar, V; Malik, S; Singh, S	1
Sundermeyer, M; Veeraputhiran, M	1
Afzal, R; Pais, P; Pogue, J; Sigamani, A; Xavier, D; Yusuf, S	1
Afzal, R; Eikelboom, J; Gupta, R; Mohan, V; Pais, P; Sigamani, A; Teo, K; Thomas, N; Xavier, D; Yusuf, S	1
Chakraborty, BS; Desai, J; Ghosh, C; Jha, V; Khamar, B; Patel, A; Shah, G; Shah, T	1
Donyai, P	1
Carey, KM; Comee, MR; Donovan, JL; Kanaan, AO	1
Afzal, R; Gao, P; Pais, P; Sigamani, A; Teo, KK; Xavier, D; Yusuf, S	1
Bautista, LE; Casas, JP; Chirinos, JA; Ferrante, D; Ferreccio, C; Herrera, VM; Medina-Lezama, J; Miranda, JJ; Oróstegui Arenas, M; Pérez, CM; Pichardo, R; Sánchez Abanto, JR; Schapochnik, N; Silva, E; Vera-Cala, LM	1
Lahmers, SM; Reina Doreste, Y; Stern, JA	1
Billot, L; Bompoint, S; Bots, ML; Cidambi, R; Field, J; Grobbee, DE; Patel, A; Poulter, N; Prabhakaran, D; Reddy, KS; Rodgers, A; Stanton, A; Thom, S	1
Billot, L; Bompoint, S; Brown, A; Burch, C; Burke, H; Cass, A; Hayman, N; Hillis, GS; Jan, S; Molanus, B; Neal, B; Patel, A; Peiris, D; Rafter, N; Reid, CM; Rodgers, A; Shiel, L; Togni, S; Tonkin, A; Usherwood, T; Webster, R	1
He, L; Lee, J; Mendell-Harary, J; Tao, B; Walker, J; Wickremasingha, P; Wight, D	1
Auroux, A; Krmar, M; Otman, O; Rac, V; Rakić, V	1
Alexander, MR; Burley, JC; Khaled, SA; Roberts, CJ; Yang, J	1
Albini, A; Bertolini, F; Calleri, A; Dallaglio, K; Gregato, G; Labanca, V; Mancuso, P; Noonan, DM; Orecchioni, S; Reggiani, F; Rossi, T; Talarico, G	1
Bots, ML; Grobbee, DE; Lafeber, M; Patel, A; Prabhakaran, D; Rodgers, A; Spiering, W; Stanton, A; Thom, S; Visseren, FL; Webster, R	1
Cheruvu, HS; Devalapalli, MMR; Sampathi, S; Shivakumar, S; Veeravalli, VB; Yertha, T	1
Gaziano, TA; Jardim, TV; Ogden, JM; Pandya, A; Rodgers, A; Sy, S; Weinstein, MC	1
Clasen, C; Re, IL; Smeets, A; Van den Mooter, G	1
Abdulwahab, S; Eissa, MS; Elsonbaty, A; Hassan, WS; Serag, A	1
Bosch, J; Christou, C; Dagenais, G; Dans, A; Gamra, H; Gao, P; Girish, P; Joseph, P; López-Jaramillo, P; McCready, T; Pais, P; Rocha, C; Santoso, A; Talukder, S; Teo, K; Tyrwhitt, J; Xavier, D; Xavier, F; Yeates, K; Yusoff, K; Yusuf, S	1

Reviews

4 review(s) available for atenolol and aspirin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Myocardial infarction in a parturient. A case report with emphasis on medication and management. Anaesthesia, 1994, Volume: 49, Issue:10 Topics: Adult; Aspirin; Atenolol; Delivery, Obstetric; Drug Therapy, Combination; Female; Humans; Myocardial Infarction; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors; Smoking	1994
Myocardial infarction in association with misuse of anabolic steroids. The Ulster medical journal, 1993, Volume: 62, Issue:2 Topics: Adult; Anabolic Agents; Aspirin; Atenolol; Doping in Sports; Echocardiography; Electrocardiography; Humans; Male; Myocardial Infarction	1993
A polypill for all? Critical review of the polypill literature for primary prevention of cardiovascular disease and stroke. The Annals of pharmacotherapy, 2012, Volume: 46, Issue:5 Topics: Antihypertensive Agents; Aspirin; Atenolol; Cardiovascular Diseases; Drug Combinations; Humans; Hydrochlorothiazide; Hypolipidemic Agents; Platelet Aggregation Inhibitors; Primary Prevention; Ramipril; Simvastatin; Stroke	2012

Trials

18 trial(s) available for atenolol and aspirin

Article	Year
Risk of cardiac events in atypical transient ischaemic attack or minor stroke. The Dutch TIA Study Group. Lancet (London, England), 1992, Sep-12, Volume: 340, Issue:8820 Topics: Aged; Aspirin; Atenolol; Cerebrovascular Disorders; Death, Sudden, Cardiac; Diagnosis, Differential; Electroencephalography; Female; Follow-Up Studies; Humans; Incidence; Ischemic Attack, Transient; Longitudinal Studies; Male; Myocardial Infarction; Netherlands; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Factors; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome	1992
Left ventricular thrombus in anterior acute myocardial infarction after thrombolysis. A GISSI-2 connected study. Circulation, 1991, Volume: 84, Issue:2 Topics: Adult; Aged; Aspirin; Atenolol; Embolism; Female; Fibrinolytic Agents; Heart; Heart Diseases; Heart Ventricles; Heparin; Humans; Injections, Subcutaneous; Male; Middle Aged; Movement; Myocardial Infarction; Thrombosis	1991
The Dutch TIA trial: protective effects of low-dose aspirin and atenolol in patients with transient ischemic attacks or nondisabling stroke. The Dutch TIA Study Group. Stroke, 1988, Volume: 19, Issue:4 Topics: Aspirin; Atenolol; Cerebrovascular Disorders; Disability Evaluation; Follow-Up Studies; Humans; Ischemic Attack, Transient; Patient Compliance	1988
[The Dutch TIA study of the preventive action of very low doses of acetylsalicylic acid and atenolol]. Nederlands tijdschrift voor geneeskunde, 1988, Feb-13, Volume: 132, Issue:7 Topics: Aspirin; Atenolol; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Ischemic Attack, Transient; Netherlands; Random Allocation	1988
Effect of purgatives on antidotal efficacy of oral activated charcoal. Human toxicology, 1986, Volume: 5, Issue:4 Topics: Administration, Oral; Adult; Antidotes; Aspirin; Atenolol; Bisacodyl; Cathartics; Charcoal; Citrates; Citric Acid; Drug Interactions; Female; Gastrointestinal Motility; Humans; Male; Metoclopramide; Phenylpropanolamine	1986
Recurrent stroke after transient ischaemic attack or minor ischaemic stroke: does the distinction between small and large vessel disease remain true to type? Dutch TIA Trial Study Group. Journal of neurology, neurosurgery, and psychiatry, 1995, Volume: 59, Issue:2 Topics: Aged; Aspirin; Atenolol; Cerebral Arteries; Cerebrovascular Disorders; Double-Blind Method; Female; Follow-Up Studies; Humans; Ischemic Attack, Transient; Male; Recurrence; Risk Factors	1995
Silent infarction on a second CT scan in 91 patients without manifest stroke in the Dutch TIA trial. Clinical neurology and neurosurgery, 1994, Volume: 96, Issue:3 Topics: Adult; Aged; Aspirin; Atenolol; Cerebral Infarction; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Putamen; Risk Factors; Tomography, X-Ray Computed	1994
Does cerebral infarction after a previous warning occur in the same vascular territory? Stroke, 1993, Volume: 24, Issue:3 Topics: Aspirin; Atenolol; Basilar Artery; Carotid Arteries; Cerebrovascular Disorders; Double-Blind Method; Follow-Up Studies; Humans; Ischemic Attack, Transient; Tomography, X-Ray Computed	1993
Incidence and prognosis of early primary ventricular fibrillation in acute myocardial infarction--results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI-2) database. The American journal of cardiology, 1998, Aug-01, Volume: 82, Issue:3 Topics: Anti-Arrhythmia Agents; Anticoagulants; Aspirin; Atenolol; Drug Administration Routes; Electrocardiography; Female; Follow-Up Studies; Heparin; Hospital Mortality; Humans; Incidence; Italy; Lidocaine; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Prognosis; Recurrence; Registries; Retrospective Studies; Survival Rate; Ventricular Fibrillation	1998
The effect of losartan versus atenolol on cardiovascular morbidity and mortality in patients with hypertension taking aspirin: the Losartan Intervention for Endpoint Reduction in hypertension (LIFE) study. Journal of the American College of Cardiology, 2005, Sep-06, Volume: 46, Issue:5 Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Aspirin; Atenolol; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Treatment Outcome	2005
The need to test the theories behind the Polypill: rationale behind the Indian Polycap Study. Nature clinical practice. Cardiovascular medicine, 2009, Volume: 6, Issue:2 Topics: Administration, Oral; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Atenolol; Capsules; Cardiovascular Agents; Cardiovascular Diseases; Diuretics; Double-Blind Method; Drug Combinations; Drug Costs; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; India; Platelet Aggregation Inhibitors; Primary Prevention; Ramipril; Research Design; Secondary Prevention; Simvastatin; Treatment Outcome	2009
Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): a phase II, double-blind, randomised trial. Lancet (London, England), 2009, Apr-18, Volume: 373, Issue:9672 Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Atenolol; Cardiovascular Diseases; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; India; Middle Aged; Platelet Aggregation Inhibitors; Ramipril; Risk Factors; Risk Reduction Behavior; Simvastatin; Treatment Outcome	2009
Preservation of bioavailability of ingredients and lack of drug-drug interactions in a novel five-ingredient polypill (polycap): a five-arm phase I crossover trial in healthy volunteers. American journal of cardiovascular drugs : drugs, devices, and other interventions, 2010, Volume: 10, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Antihypertensive Agents; Area Under Curve; Aspirin; Atenolol; Biological Availability; Capsules; Cardiovascular Diseases; Chromatography, Liquid; Cross-Over Studies; Drug Combinations; Drug Interactions; Humans; Hydrochlorothiazide; Hypolipidemic Agents; Male; Middle Aged; Platelet Aggregation Inhibitors; Ramipril; Risk Factors; Simvastatin; Tandem Mass Spectrometry; Young Adult	2010
Comparison of risk factor reduction and tolerability of a full-dose polypill (with potassium) versus low-dose polypill (polycap) in individuals at high risk of cardiovascular diseases: the Second Indian Polycap Study (TIPS-2) investigators. Circulation. Cardiovascular quality and outcomes, 2012, Jul-01, Volume: 5, Issue:4 Topics: Administration, Oral; Aged; Analysis of Variance; Antihypertensive Agents; Aspirin; Atenolol; Biomarkers; Blood Pressure; Capsules; Cardiovascular Diseases; Cholesterol, LDL; Creatinine; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; India; Male; Middle Aged; Platelet Aggregation Inhibitors; Polypharmacy; Potassium; Ramipril; Risk Assessment; Risk Factors; Simvastatin; Tablets; Time Factors; Treatment Outcome	2012
Effects of a fixed-dose combination strategy on adherence and risk factors in patients with or at high risk of CVD: the UMPIRE randomized clinical trial. JAMA, 2013, Sep-04, Volume: 310, Issue:9 Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atenolol; Blood Pressure; Cardiovascular Diseases; Cholesterol, LDL; Drug Combinations; Female; Humans; Hydrochlorothiazide; Lisinopril; Male; Medication Adherence; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Simvastatin; Treatment Outcome	2013
A pragmatic randomized trial of a polypill-based strategy to improve use of indicated preventive treatments in people at high cardiovascular disease risk. European journal of preventive cardiology, 2015, Volume: 22, Issue:7 Topics: Administration, Oral; Adrenergic beta-1 Receptor Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Atenolol; Australia; Biomarkers; Blood Pressure; Cardiovascular Diseases; Cholesterol; Drug Combinations; Drugs, Generic; Female; General Practice; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Lisinopril; Male; Middle Aged; Platelet Aggregation Inhibitors; Polypharmacy; Primary Prevention; Prospective Studies; Risk Factors; Simvastatin; Sodium Chloride Symporter Inhibitors; Tablets; Time Factors; Treatment Outcome	2015
Impact of switching from different treatment regimens to a fixed-dose combination pill (polypill) in patients with cardiovascular disease or similarly high risk. European journal of preventive cardiology, 2017, Volume: 24, Issue:9 Topics: Administration, Oral; Aged; Antihypertensive Agents; Aspirin; Atenolol; Biomarkers; Blood Pressure; Cardiovascular Diseases; Cholesterol, LDL; Drug Combinations; Drug Substitution; Europe; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; India; Lisinopril; Male; Medication Adherence; Middle Aged; Platelet Aggregation Inhibitors; Polypharmacy; Risk Assessment; Risk Factors; Simvastatin; Tablets; Time Factors; Treatment Outcome	2017
Polypill with or without Aspirin in Persons without Cardiovascular Disease. The New England journal of medicine, 2021, 01-21, Volume: 384, Issue:3 Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atenolol; Blood Pressure; Cardiovascular Diseases; Cholesterol, LDL; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Incidence; Male; Medication Adherence; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Simvastatin	2021

Other Studies

54 other study(ies) available for atenolol and aspirin

Article	Year
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes. Journal of medicinal chemistry, 1998, Mar-26, Volume: 41, Issue:7 Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet	1998
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Characterization of the drug binding specificity of rat liver fatty acid binding protein. Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13 Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies. European journal of medicinal chemistry, 2020, Oct-15, Volume: 204 Topics: Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Design; Enzyme Inhibitors; Humans; Hydrazones; Hypersensitivity; Lung; Male; Mice	2020
Safety of combined intravenous beta-adrenergic blockade (atenolol or metoprolol) and thrombolytic therapy in acute myocardial infarction. The American journal of cardiology, 1992, Jun-01, Volume: 69, Issue:17 Topics: Administration, Oral; Adult; Aspirin; Atenolol; Combined Modality Therapy; Female; Humans; Infusions, Intravenous; Male; Metoprolol; Middle Aged; Myocardial Infarction; Recurrence; Thrombolytic Therapy	1992
Diltiazem-induced granulomatous hepatitis. Histopathology, 1991, Volume: 18, Issue:5 Topics: Aged; Aspirin; Atenolol; Chemical and Drug Induced Liver Injury; Diltiazem; Female; Granuloma; Humans; Liver; Liver Function Tests; Myocardial Infarction	1991
[The Dutch TIA study of the preventive action of very low doses acetylsalicylic acid and atenolol]. Nederlands tijdschrift voor geneeskunde, 1988, Apr-16, Volume: 132, Issue:16 Topics: Aspirin; Atenolol; Bleeding Time; Humans; Platelet Aggregation	1988
Atenolol interaction with aspirin, allopurinol, and ampicillin. Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:3 Topics: Adult; Allopurinol; Ampicillin; Aspirin; Atenolol; Biological Availability; Blood Pressure; Drug Interactions; Female; Heart Rate; Humans; Kinetics; Male; Physical Exertion; Propanolamines	1983
Myocardial infarction caused by coronary artery myocardial bridge. American heart journal, 1997, Volume: 133, Issue:4 Topics: Adrenergic beta-Antagonists; Adult; Aged; Aspirin; Atenolol; Cardiac Catheterization; Coronary Angiography; Coronary Disease; Electrocardiography; Female; Humans; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Systole	1997
Hospital-acquired hyperkalaemia. Postgraduate medical journal, 1997, Volume: 73, Issue:861 Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Atenolol; Heparin; Humans; Hyperkalemia; Kidney Failure, Chronic; Male; Middle Aged	1997
Refining instructional text generation after evaluation. Artificial intelligence in medicine, 1999, Volume: 17, Issue:1 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Artificial Intelligence; Aspirin; Atenolol; Decision Making, Computer-Assisted; Drug Prescriptions; Evaluation Studies as Topic; Humans; Male; Middle Aged	1999
The effect of vasodilators on aspirin-induced antagonism of t-PA thrombolysis. Neurological research, 2001, Volume: 23, Issue:7 Topics: Animals; Antihypertensive Agents; Aspirin; Atenolol; Brain Ischemia; Cerebrovascular Circulation; Drug Interactions; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hydralazine; Male; Nitric Oxide; Nitric Oxide Donors; Prostaglandins, Synthetic; Rabbits; Thromboembolism; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome; Vasodilator Agents	2001
[A case of familial restrictive cardiomyopathy]. Klinicheskaia meditsina, 2002, Volume: 80, Issue:9 Topics: Adult; Aged; Anti-Arrhythmia Agents; Antihypertensive Agents; Aspirin; Atenolol; Atrial Fibrillation; Cardiomyopathy, Restrictive; Cardiotonic Agents; Echocardiography; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Hemodynamics; Humans; Hypertension; Niacin; Platelet Aggregation Inhibitors; Potassium Magnesium Aspartate; Propranolol; Time Factors; Vasodilator Agents	2002
Niacin and the National Cholesterol Education Program Adult Treatment Panel III Guidelines: case studies. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2003, Jul-01, Volume: 60, Issue:13 Suppl 2 Topics: Aspirin; Atenolol; Blood Chemical Analysis; Coronary Disease; Female; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Niacin; Obesity; Risk Factors; Simvastatin	2003
[Diagnosis and therapy of stable angina in Russian Federation (International Study ATP - angina treatment pattern)]. Kardiologiia, 2003, Volume: 43, Issue:5 Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Atenolol; Body Mass Index; Calcium Channel Blockers; Diabetes Complications; Drug Therapy, Combination; Electrocardiography; Female; Fibrinolytic Agents; Humans; Hyperlipidemias; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Russia; Sex Factors; Smoking; Time Factors; Vasodilator Agents; Verapamil	2003
[Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized]. MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Alcohol Drinking; Anticholesteremic Agents; Anticoagulants; Antihypertensive Agents; Arrhythmias, Cardiac; Aspirin; Atenolol; Atrial Fibrillation; Carotid Artery, Internal; Carotid Stenosis; Chlorthalidone; Clinical Trials as Topic; Diabetes Complications; Diuretics; Doxazosin; Female; Fibrinolytic Agents; Hormone Replacement Therapy; Humans; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Life Style; Losartan; Male; Neurology; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Pravastatin; Primary Prevention; Risk Factors; Simvastatin; Smoking; Societies, Medical; Stroke	2003
Regression dilution of systolic and diastolic blood pressure in patients with established cerebrovascular disease. Journal of clinical epidemiology, 2003, Volume: 56, Issue:11 Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atenolol; Blood Pressure; Diastole; Female; Follow-Up Studies; Humans; Male; Middle Aged; Proportional Hazards Models; Randomized Controlled Trials as Topic; Regression Analysis; Reproducibility of Results; Risk; Stroke; Systole	2003
Effect of Larrea divaricata Cav. extract and nordihydroguaiaretic acid upon peroxidase secretion in rat submandibulary glands. Pharmacological research, 2004, Volume: 49, Issue:5 Topics: 3,3'-Diaminobenzidine; Animals; Argentina; Aspirin; Atenolol; Butoxamine; Dinoprostone; Dobutamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Forecasting; Larrea; Masoprocol; Peroxidase; Plant Extracts; Plant Leaves; Prazosin; Propranolol; Rats; Rats, Wistar; Submandibular Gland; Water	2004
Hypertension and insulin resistance are not directly related in obese dogs. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5 Topics: Adrenergic beta-Antagonists; Animals; Aspirin; Atenolol; Blood Glucose; Clonidine; Diet, Sodium-Restricted; Dietary Fats; Dogs; Female; Furosemide; Hemodynamics; Hypertension; I-kappa B Kinase; Insulin; Insulin Resistance; Male; Models, Animal; Models, Biological; Obesity; Prazosin; Protein Serine-Threonine Kinases; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sympathetic Nervous System	2004
Zero-order release of aspirin, theophylline and atenolol in water from novel methylcellulose glutarate matrix tablets. International journal of pharmaceutics, 2006, Aug-02, Volume: 318, Issue:1-2 Topics: Adrenergic beta-Antagonists; Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atenolol; Bronchodilator Agents; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Excipients; Glutarates; Magnetic Resonance Spectroscopy; Methylcellulose; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; Theophylline; Viscosity	2006
Transport characteristics of zolmitriptan in a human intestinal epithelial cell line Caco-2. The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:5 Topics: Aspirin; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport; Caco-2 Cells; Cetirizine; Cimetidine; Diffusion; Dose-Response Relationship, Drug; Drug Interactions; Flunarizine; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Oxazolidinones; Permeability; Propranolol; Serotonin Receptor Agonists; Sodium-Hydrogen Exchangers; Tryptamines	2007
Pharmacokinetic profile of atenolol aspirinate. Archiv der Pharmazie, 2007, Volume: 340, Issue:9 Topics: Animals; Antihypertensive Agents; Area Under Curve; Aspirin; Atenolol; Gastric Mucosa; Half-Life; Humans; Microwaves; Models, Molecular; Mutagenicity Tests; Prodrugs	2007
LC and LC-MS methods for the investigation of polypills for the treatment of cardiovascular diseases. Part 1. Separation of active components and classification of their interaction/degradation products. Journal of pharmaceutical and biomedical analysis, 2008, Jul-15, Volume: 47, Issue:3 Topics: Aspirin; Atenolol; Atorvastatin; Cardiovascular Agents; Chromatography, High Pressure Liquid; Drug Combinations; Drug Interactions; Drug Stability; Heptanoic Acids; Hydrochlorothiazide; Lisinopril; Pravastatin; Pyrroles; Simvastatin; Spectrometry, Mass, Electrospray Ionization	2008
Polypill for the treatment of cardiovascular diseases part 2. LC-MS/TOF characterization of interaction/degradation products of atenolol/lisinopril and aspirin, and mechanisms of formation thereof. Journal of pharmaceutical and biomedical analysis, 2008, Nov-04, Volume: 48, Issue:3 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Atenolol; Cardiovascular Agents; Chromatography, Liquid; Drug Combinations; Drug Interactions; Lisinopril; Mass Spectrometry; Molecular Structure; Molecular Weight; Platelet Aggregation Inhibitors	2008
Rhabdomyolysis resulting from pharmacologic interaction between erlotinib and simvastatin. Clinical lung cancer, 2008, Volume: 9, Issue:4 Topics: Aged; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atenolol; Azetidines; Carcinoma, Non-Small-Cell Lung; Coronary Artery Disease; Drug Interactions; Erlotinib Hydrochloride; Ezetimibe; Female; Humans; Hyperlipidemias; Hypertension; Lung Neoplasms; Neoplasm Recurrence, Local; Protein Kinase Inhibitors; Quinazolines; Rhabdomyolysis; Simvastatin; Tomography, X-Ray Computed	2008
Quality of medicines stored together in multi-compartment compliance aids. Journal of clinical pharmacy and therapeutics, 2010, Volume: 35, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Atenolol; Biological Availability; Chemical Phenomena; Drug Packaging; Drug Stability; Drug Storage; Excipients; Hardness; Humans; Humidity; Light; Patient Compliance; Solubility; Tablets; Temperature	2010
A 'polypill' aimed at preventing cardiovascular disease could prove highly cost-effective for use in Latin America. Health affairs (Project Hope), 2013, Volume: 32, Issue:1 Topics: Aged; Antihypertensive Agents; Aspirin; Atenolol; Cardiovascular Diseases; Cohort Studies; Cost-Benefit Analysis; Developing Countries; Drug Combinations; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Latin America; Male; Markov Chains; Middle Aged; Quality-Adjusted Life Years; Ramipril; Randomized Controlled Trials as Topic; Risk Factors; Simvastatin; Sodium Chloride Symporter Inhibitors	2013
ECG of the month. Multiple episodes of collapse in a cat. Journal of the American Veterinary Medical Association, 2013, Apr-01, Volume: 242, Issue:7 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Aspirin; Atenolol; Calcium Channel Blockers; Cat Diseases; Cats; Diltiazem; Electrocardiography; Male; Platelet Aggregation Inhibitors	2013
Lack of effect of colesevelam HCl on the single-dose pharmacokinetics of aspirin, atenolol, enalapril, phenytoin, rosiglitazone, and sitagliptin. Diabetes research and clinical practice, 2014, Volume: 104, Issue:3 Topics: Adolescent; Adult; Allylamine; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Anticonvulsants; Antihypertensive Agents; Area Under Curve; Aspirin; Atenolol; Colesevelam Hydrochloride; Dose-Response Relationship, Drug; Drug Interactions; Enalapril; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Phenytoin; Pyrazines; Rosiglitazone; Sitagliptin Phosphate; Thiazolidinediones; Tissue Distribution; Triazoles; Young Adult	2014
The adsorption of pharmaceutically active compounds from aqueous solutions onto activated carbons. Journal of hazardous materials, 2015, Jan-23, Volume: 282 Topics: Adsorption; Aspirin; Atenolol; Carbon; Diclofenac; Salicylic Acid; Solutions; Surface Properties; Water Pollutants, Chemical; Water Purification	2015
3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles. Journal of controlled release : official journal of the Controlled Release Society, 2015, Nov-10, Volume: 217 Topics: Aspirin; Atenolol; Delayed-Action Preparations; Drug Combinations; Drug Liberation; Excipients; Hydrochlorothiazide; Powder Diffraction; Pravastatin; Printing, Three-Dimensional; Ramipril; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; X-Ray Diffraction	2015
Aspirin and atenolol enhance metformin activity against breast cancer by targeting both neoplastic and microenvironment cells. Scientific reports, 2016, Jan-05, Volume: 6 Topics: Adipose Tissue, White; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Atenolol; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Synergism; Electron Transport Complex I; Female; Humans; Metformin; NAD; Neoplasm Metastasis; Stem Cells; Triple Negative Breast Neoplasms; Tumor Burden; Tumor Microenvironment; Xenograft Model Antitumor Assays	2016
Hansen solubility parameters for assay method optimization of simvastatin, ramipril, atenolol, hydrochlorothiazide and aspirin in human plasma using liquid chromatography with tandem mass spectrometry. Journal of separation science, 2017, Volume: 40, Issue:18 Topics: Aspirin; Atenolol; Chromatography, Liquid; Humans; Hydrochlorothiazide; Ramipril; Reproducibility of Results; Simvastatin; Solubility; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2017
Modeling the cost effectiveness and budgetary impact of Polypills for secondary prevention of cardiovascular disease in the United States. American heart journal, 2019, Volume: 214 Topics: Adrenergic beta-Antagonists; Aspirin; Atenolol; Budgets; Cardiovascular Diseases; Cost Savings; Cost-Benefit Analysis; Drug Combinations; Drug Costs; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Life Expectancy; Male; Medication Adherence; Middle Aged; Nutrition Surveys; Platelet Aggregation Inhibitors; Ramipril; Renin-Angiotensin System; Secondary Prevention; Stroke; United States	2019
Fixed dose combinations for cardiovascular treatment via coaxial electrospraying: Coated amorphous solid dispersion particles. International journal of pharmaceutics, 2020, Mar-15, Volume: 577 Topics: Acetaminophen; Aspirin; Atenolol; Drug Combinations; Drug Compounding; Drug Liberation; Fenofibrate; Hydrogen-Ion Concentration; Polyethylene Glycols; Polymethacrylic Acids; Polyvinyls; Powders	2020
Analysis of quinary therapy targeting multiple cardiovascular diseases using UV spectrophotometry and chemometric tools. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2020, Sep-05, Volume: 238 Topics: Algorithms; Aspirin; Atenolol; Capsules; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Humans; Hydrochlorothiazide; Least-Squares Analysis; Ramipril; Simvastatin; Spectrophotometry, Ultraviolet	2020