Page last updated: 2024-09-04

atazanavir sulfate and posaconazole

atazanavir sulfate has been researched along with posaconazole in 2 studies

Compound Research Comparison

Studies (atazanavir sulfate)	Trials (atazanavir sulfate)	Recent Studies (post-2010) (atazanavir sulfate)	Studies (posaconazole)	Trials (posaconazole)	Recent Studies (post-2010) (posaconazole)
1,102	246	590	1,575	103	1,014

Protein Interaction Comparison

Protein	Taxonomy	posaconazole (IC50)
Bile salt export pump	Homo sapiens (human)	8.1
Steroid 17-alpha-hydroxylase/17,20 lyase	Homo sapiens (human)	0.921
Cytochrome P450 3A4	Homo sapiens (human)	0.2458
Aromatase	Homo sapiens (human)	8.4
Cytochrome P450 2C9	Homo sapiens (human)	7.2
Cytochrome P450 11B1, mitochondrial	Homo sapiens (human)	0.31
Cytochrome P450 11B2, mitochondrial	Homo sapiens (human)	0.021
Sterol 14-alpha demethylase	Trypanosoma cruzi strain CL Brener	0.464
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	6

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Krishna, G; Ma, L; Martinho, M; McLeod, J; Moton, A; Seiberling, M	1
Augustijns, P; Brouwers, J; Elkhabaz, A; Moseson, DE; Taylor, LS	1

Trials

1 trial(s) available for atazanavir sulfate and posaconazole

Article	Year
Effects of oral posaconazole on the pharmacokinetics of atazanavir alone and with ritonavir or with efavirenz in healthy adult volunteers. Journal of acquired immune deficiency syndromes (1999), 2009, Aug-01, Volume: 51, Issue:4 Topics: Administration, Oral; Adult; Alkynes; Anti-HIV Agents; Area Under Curve; Atazanavir Sulfate; Benzoxazines; Cross-Over Studies; Cyclopropanes; Drug Interactions; Female; Humans; Male; Middle Aged; Oligopeptides; Pyridines; Ritonavir; Triazoles	2009

Article

Year

Effects of oral posaconazole on the pharmacokinetics of atazanavir alone and with ritonavir or with efavirenz in healthy adult volunteers.

Journal of acquired immune deficiency syndromes (1999), 2009, Aug-01, Volume: 51, Issue:4

Topics: Administration, Oral; Adult; Alkynes; Anti-HIV Agents; Area Under Curve; Atazanavir Sulfate; Benzoxazines; Cross-Over Studies; Cyclopropanes; Drug Interactions; Female; Humans; Male; Middle Aged; Oligopeptides; Pyridines; Ritonavir; Triazoles

2009

Other Studies

1 other study(ies) available for atazanavir sulfate and posaconazole

Article	Year
Interplay of Supersaturation and Solubilization: Lack of Correlation between Concentration-Based Supersaturation Measurements and Membrane Transport Rates in Simulated and Aspirated Human Fluids. Molecular pharmaceutics, 2019, 12-02, Volume: 16, Issue:12 Topics: Atazanavir Sulfate; Biological Transport; Body Fluids; Chemistry, Pharmaceutical; Crystallization; Diffusion; Humans; Kinetics; Solubility; Thermodynamics; Triazoles	2019

Article

Year

Interplay of Supersaturation and Solubilization: Lack of Correlation between Concentration-Based Supersaturation Measurements and Membrane Transport Rates in Simulated and Aspirated Human Fluids.

Molecular pharmaceutics, 2019, 12-02, Volume: 16, Issue:12

Topics: Atazanavir Sulfate; Biological Transport; Body Fluids; Chemistry, Pharmaceutical; Crystallization; Diffusion; Humans; Kinetics; Solubility; Thermodynamics; Triazoles

2019