Page last updated: 2024-09-04

atazanavir sulfate and maraviroc

atazanavir sulfate has been researched along with maraviroc in 6 studies

Compound Research Comparison

Studies
(atazanavir sulfate)
Trials
(atazanavir sulfate)
Recent Studies (post-2010)
(atazanavir sulfate)
Studies
(maraviroc)
Trials
(maraviroc)
Recent Studies (post-2010) (maraviroc)
1,102246590785124539

Protein Interaction Comparison

ProteinTaxonomyatazanavir sulfate (IC50)maraviroc (IC50)
Cytochrome P450 3A4Homo sapiens (human)3.1
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0014
C-C chemokine receptor type 5Homo sapiens (human)0.0044
C-C chemokine receptor type 5Mus musculus (house mouse)0.0052

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Abel, S; Muirhead, GJ; Ridgway, CE; Russell, D; Taylor-Worth, RJ1
Collins, C; Dickins, M; Hyland, R; Jones, B; Jones, H1
Craig, C; Fätkenheuer, G; Heera, J; Leal, M; McFadyen, L; Mildvan, D; Mills, A; Podzamczer, D; Portsmouth, S; Rinehart, AR; Than, S; Valdez, H; Valluri, SR; Vourvahis, M1
Cecka, F; Cerveny, L; Huliciak, M; Martinec, O; Staud, F; Vokral, I1
Adamson, L; Akkina, R; Blake, K; Burgunder, EM; Devanathan, AS; Garcia, JV; Kashuba, ADM; Kovarova, M; Luciw, P; Pirone, JR; Remling-Mulder, L; Rosen, EP; Schauer, AP; Srinivas, N; Sykes, C; White, NR1
Auclair, M; Capeau, J; Fellahi, S; Garcia, M; Guénantin, AC1

Trials

2 trial(s) available for atazanavir sulfate and maraviroc

ArticleYear
Effects of CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers.
    British journal of clinical pharmacology, 2008, Volume: 65 Suppl 1

    Topics: Adolescent; Anti-HIV Agents; Antifungal Agents; Atazanavir Sulfate; CCR5 Receptor Antagonists; Cyclohexanes; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; Humans; Ketoconazole; Male; Maraviroc; Middle Aged; Oligopeptides; Pyridines; Saquinavir; Statistics as Topic; Triazoles

2008
Maraviroc once-daily nucleoside analog-sparing regimen in treatment-naive patients: randomized, open-label pilot study.
    Journal of acquired immune deficiency syndromes (1999), 2013, Feb-01, Volume: 62, Issue:2

    Topics: Adenine; Adolescent; Adult; Aged; Anti-HIV Agents; Atazanavir Sulfate; CCR5 Receptor Antagonists; CD4 Lymphocyte Count; Cyclohexanes; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Male; Maraviroc; Middle Aged; Oligopeptides; Organophosphonates; Pilot Projects; Pyridines; Ritonavir; RNA, Viral; Tenofovir; Triazoles; Viral Load; Young Adult

2013

Other Studies

4 other study(ies) available for atazanavir sulfate and maraviroc

ArticleYear
Maraviroc: in vitro assessment of drug-drug interaction potential.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:4

    Topics: Area Under Curve; Atazanavir Sulfate; Cyclohexanes; Cytochrome P-450 CYP3A; Drug Interactions; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Ketoconazole; Liver; Male; Maraviroc; Microsomes, Liver; Oligopeptides; Predictive Value of Tests; Pyridines; Ritonavir; Saquinavir; Triazoles

2008
Anti-HIV and Anti-Hepatitis C Virus Drugs Inhibit P-Glycoprotein Efflux Activity in Caco-2 Cells and Precision-Cut Rat and Human Intestinal Slices.
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:11

    Topics: Aged; Animals; Anti-HIV Agents; Antiviral Agents; Atazanavir Sulfate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Caco-2 Cells; Carbamates; Drug Interactions; Female; Fluorenes; Hepatitis C; HIV Infections; Humans; Imidazoles; Intestines; Lopinavir; Male; Maraviroc; Middle Aged; Pyrrolidines; Rats; Rats, Wistar; Ritonavir; Saquinavir; Valine; Zidovudine

2019
Antiretroviral Penetration across Three Preclinical Animal Models and Humans in Eight Putative HIV Viral Reservoirs.
    Antimicrobial agents and chemotherapy, 2019, 12-20, Volume: 64, Issue:1

    Topics: Animals; Anti-HIV Agents; Anti-Retroviral Agents; Atazanavir Sulfate; Emtricitabine; Female; HIV Infections; Humans; In Vitro Techniques; Maraviroc; Mice; Raltegravir Potassium; Tenofovir

2019
HIV antiretroviral drugs, dolutegravir, maraviroc and ritonavir-boosted atazanavir use different pathways to affect inflammation, senescence and insulin sensitivity in human coronary endothelial cells.
    PloS one, 2020, Volume: 15, Issue:1

    Topics: Anti-HIV Agents; Atazanavir Sulfate; Cells, Cultured; Comorbidity; Coronary Vessels; Endothelial Cells; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; Humans; Insulin Resistance; Male; Maraviroc; NF-kappa B; Oxazines; Piperazines; Pyridones; Ritonavir; Signal Transduction; Sirtuin 1; Ubiquitin Thiolesterase

2020