Page last updated: 2024-09-04

atazanavir and benzbromarone

atazanavir has been researched along with benzbromarone in 4 studies

Compound Research Comparison

Studies (atazanavir)	Trials (atazanavir)	Recent Studies (post-2010) (atazanavir)	Studies (benzbromarone)	Trials (benzbromarone)	Recent Studies (post-2010) (benzbromarone)
75	1	37	482	59	208

Protein Interaction Comparison

Protein	Taxonomy	benzbromarone (IC50)
envelope glycoprotein	Human immunodeficiency virus 1	12.8
nuclear receptor corepressor 2 isoform 2	Homo sapiens (human)	4.811
peroxisome proliferator-activated receptor gamma isoform 2	Homo sapiens (human)	4.811
Adenosine receptor A3	Homo sapiens (human)	5.222
60 kDa heat shock protein, mitochondrial	Homo sapiens (human)	9.1
Cytochrome P450 2C9	Homo sapiens (human)	1.0895
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	5.222
Mitogen-activated protein kinase 1	Homo sapiens (human)	1.946
Multidrug resistance-associated protein 1	Homo sapiens (human)	4
5-hydroxytryptamine receptor 2B	Homo sapiens (human)	1.804
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	5.222
Cytochrome P450 2J2	Homo sapiens (human)	4.26
10 kDa heat shock protein, mitochondrial	Homo sapiens (human)	9.1
Aldo-keto reductase family 1 member C1	Homo sapiens (human)	0.048
Mitogen-activated protein kinase 14	Homo sapiens (human)	1.235
Solute carrier family 22 member 6	Homo sapiens (human)	4.6
Monocarboxylate transporter 2	Rattus norvegicus (Norway rat)	9
Solute carrier family 22 member 12	Homo sapiens (human)	0.8695
Eyes absent homolog 3	Homo sapiens (human)	8.3
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	0.2
M17 leucyl aminopeptidase	Plasmodium falciparum 3D7	81.89
M1-family alanyl aminopeptidase	Plasmodium falciparum 3D7	62.78

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (75.00)	24.3611
2020's	1 (25.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF	1

Reviews

2 review(s) available for atazanavir and benzbromarone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators. European journal of medicinal chemistry, 2022, Jul-05, Volume: 237 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells	2022

Other Studies

2 other study(ies) available for atazanavir and benzbromarone

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012

Article

Year

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

Chemical research in toxicology, 2010, Volume: 23, Issue:1

Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010

Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012