at 2153 has been researched along with razoxane in 13 studies
| Studies (at 2153) | Trials (at 2153) | Recent Studies (post-2010) (at 2153) | Studies (razoxane) | Trials (razoxane) | Recent Studies (post-2010) (razoxane) |
|---|---|---|---|---|---|
| 13 | 0 | 0 | 824 | 115 | 56 |
| Protein | Taxonomy | at 2153 (IC50) | razoxane (IC50) |
|---|---|---|---|
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 3.19 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, WC; Han, JK; Xin, WJ; Zhang, TM; Zhang, Y; Zhao, BL | 1 |
| Dan, N; Li, XJ; Xin, WJ; Zhang, TM; Zhao, BL | 1 |
| Li, GD; Liu, TX; Wang, MY; Zhang, TM | 1 |
| Ren, YF; Wang, MY; Wang, QD; Zhang, TM | 1 |
| Bhat, HB; Ferrans, VJ; Herman, EH; Witiak, DT | 1 |
| Liu, J; Ye, QX; Zhang, TM; Zhang, Y; Zhang, ZY | 1 |
| Hua, HY; Zhang, TM; Zhang, Y | 1 |
| Chen, RT; Lu, DY; Xu, B; Zhang, X | 1 |
| Ding, J; Lu, DY; Xu, B | 1 |
| Ding, J; Hu, CX; Huang, M; Li, MH; Lin, LP; Lu, DY; Lu, W; Tong, LJ; Xu, CH; Yang, WY; Zhang, XW | 1 |
| Ding, J; Huang, M; Lu, DY; Xu, B; Xu, CH; Zhu, H | 1 |
| Lu, DY; Lu, TR | 2 |
2 review(s) available for at 2153 and razoxane
| Article | Year |
|---|---|
Anticancer activities and mechanisms of bisdioxopiperazine compounds probimane and MST-16.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Humans; Mice; Mice, Inbred C57BL; Piperazines; Razoxane | 2010 |
Antimetastatic activities and mechanisms of bisdioxopiperazine compounds.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Transformed; Fibrinogen; Humans; Mice; Molecular Targeted Therapy; Neoplasm Metastasis; Piperazines; Razoxane | 2010 |
11 other study(ies) available for at 2153 and razoxane
| Article | Year |
|---|---|
[Scavenging of probimane on semiquinone free radical formation by doxorubicin in rat heart].
Topics: Animals; Antineoplastic Agents; Benzoquinones; Doxorubicin; Free Radical Scavengers; Free Radicals; Male; Mitochondria, Heart; Myocardium; Rats; Rats, Inbred Strains; Razoxane | 1991 |
[Scavenging effects of probimane on active oxygen free radicals by electron spin resonance].
Topics: Antineoplastic Agents; Ascorbic Acid; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Neutrophils; Oxygen Consumption; Piperazines; Razoxane; Vitamin E | 1989 |
[Effects of bimolane and probimane on the incorporation of (3H)TdR, (3H)UR and (3H)Leu into Ehrlich ascites carcinoma cells iv vitro].
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Female; Leucine; Male; Mice; Piperazines; Razoxane; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine | 1988 |
[Antineoplastic action and toxicity of probimane and its effect on immunologic functions in mice].
Topics: Animals; Antineoplastic Agents; B-Lymphocytes; Female; Graft vs Host Reaction; Male; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Piperazines; Rats; Rats, Inbred Strains; Razoxane | 1987 |
Reduction of chronic doxorubicin cardiotoxicity in beagle dogs by bis-morpholinomethyl derivative of razoxane (ICRF-159).
Topics: Animals; Blood Cell Count; Body Weight; Dogs; Doxorubicin; Drug Evaluation, Preclinical; Female; Heart Diseases; Hematocrit; Hematologic Diseases; Male; Piperazines; Razoxane | 1987 |
Synergistic effect of probimane on anticancer cytotoxicity of doxorubicin in vitro.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Ehrlich Tumor; Doxorubicin; Drug Synergism; Male; Malondialdehyde; Mice; Mitochondria; Neoplasm Transplantation; Razoxane; Tumor Cells, Cultured | 1994 |
Inhibitory effect of dioxopiperazine compounds on malondialdehyde formation induced by doxorubicin in rat liver mitochondria in vitro.
Topics: Animals; Antineoplastic Agents; Chlorides; Doxorubicin; Edetic Acid; Ferric Compounds; In Vitro Techniques; Male; Malondialdehyde; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Razoxane | 1993 |
[Distribution of 14C labeled at dioxopiperazine or methyl morpholine group of probimane by whole body autoradiography].
Topics: Animals; Antineoplastic Agents; Autoradiography; Carbon Radioisotopes; Humans; Leukemia L1210; Lung Neoplasms; Mice; Mice, Nude; Razoxane; Tissue Distribution | 1993 |
Antitumor effects of two bisdioxopiperazines against two experimental lung cancer models in vivo.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; China; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Razoxane; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2004 |
Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation by probimane and MST-16 in human tumor cell lines.
Topics: Antineoplastic Agents; Chromosome Segregation; G2 Phase; Humans; Piperazines; Razoxane; Tumor Cells, Cultured | 2005 |
Medicinal chemistry of probimane and MST-16: comparison of anticancer effects between bisdioxopiperazines.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Mice; Mice, Nude; Molecular Structure; Piperazines; Razoxane; Structure-Activity Relationship; Time Factors; Xenograft Model Antitumor Assays | 2006 |