Compounds > astemizole

astemizole and isomethyleugenol

astemizole has been researched along with isomethyleugenol in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kourounakis, PN; Tani, E1
Jeong, HE; Lee, SS; Liu, KH; Moon, T; Oh, SJ; Ryu, JY; Shin, JG; Yoon, CN; Yun, CH1
Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS1
Chen, K; Chen, L; Ding, H; Du, D; Jiang, H; Jiang, X; Jiao, L; Kong, X; Lian, F; Liu, J; Liu, X; Lu, J; Luo, C; Shen, J; Zhang, N; Zheng, M; Zhu, K1

Other Studies

4 other study(ies) available for astemizole and isomethyleugenol

ArticleYear
Action of oxatomide on the hepatic microsomal enzyme system. Effect of the monoxygenase and peroxidase activity of P-450 on drug N-demethylations.
    Research communications in chemical pathology and pharmacology, 1993, Volume: 80, Issue:3

    Topics: Aminopyrine; Animals; Astemizole; Cytochrome P-450 Enzyme System; Ethylmorphine; Female; In Vitro Techniques; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Peroxidase; Piperazines; Rats; Rats, Wistar; Zoxazolamine

1993
Identification and functional characterization of novel CYP2J2 variants: G312R variant causes loss of enzyme catalytic activity.
    Pharmacogenetics and genomics, 2005, Volume: 15, Issue:2

    Topics: Alleles; Animals; Astemizole; Butyrophenones; Catalysis; Cell Line; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; DNA Primers; Dose-Response Relationship, Drug; Gene Frequency; Genetic Variation; Heterozygote; Histamine H1 Antagonists; Humans; Insecta; Kinetics; Korea; Methylation; Models, Molecular; Mutation; Oxygenases; Piperidines; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Recombinant Proteins; Recombination, Genetic; Sequence Analysis, DNA; Time Factors

2005
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5

    Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine

2012
Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2.
    Journal of medicinal chemistry, 2014, Nov-26, Volume: 57, Issue:22

    Topics: Astemizole; Binding, Competitive; Catalysis; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Histones; Humans; Lymphoma; Magnetic Resonance Spectroscopy; Methylation; Models, Molecular; Molecular Docking Simulation; Neoplasms; Polycomb Repressive Complex 2; Protein Interaction Mapping; Protein Processing, Post-Translational

2014