astemizole has been researched along with histamine in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (50.00) | 18.7374 |
| 1990's | 8 (26.67) | 18.2507 |
| 2000's | 2 (6.67) | 29.6817 |
| 2010's | 5 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biagini, GA; Chandramohanadas, R; Darling, C; DeGrado, WF; Diamond, SL; Fisher, N; Greenbaum, DC; Jing, H; Jo, H; Lucumi, E; Napper, AD; Shone, AE; Ward, SA | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Benoît, C; Cartier, A; Ghezzo, H; Malo, JL | 1 |
| Eisen, A; Ginzburg, R; Paran, Y; Seltzer, Z | 1 |
| Humphreys, F; Hunter, JA | 1 |
| Cartier, A; Fu, CL; Ghezzo, H; L'Archevêque, J; Malo, JL | 1 |
| McMillan, JL; Simons, FE; Simons, KJ | 1 |
| Lahti, A; Työlahti, H | 1 |
| Foxwell, MH; Johnson, DN; Kilpatrick, BF; Leonard, CA; Nolan, JC; Proakis, AG; Stephens, DJ; Yanni, JM | 1 |
| Emanuel, MB; Holgate, ST; Howarth, PH | 1 |
| Araujo, OE; Flowers, FP; Nieves, CH | 1 |
| Beasley, R; Holgate, S; Rafferty, P; Southgate, P | 1 |
| Feinberg, G; Stokes, TC | 1 |
| Gendreau-Reid, L; Simons, FE; Simons, KJ | 1 |
| Janssen, M; Janssen, PA; Janssens, F; Luyckx, M; Stokbroekx, RA; Torremans, J | 2 |
| Awouters, F; Janssen, PA; Janssens, F; Neimegeers, CJ; Van Nueten, JM; Van Wauwe, J | 1 |
| Burvenich, C; Peeters, G | 1 |
| Schuurkes, JA; Van Nueten, JM | 1 |
| Bateman, DN; Chapman, PH; Rawlins, MD | 1 |
| Krause, LB; Shuster, S | 1 |
| Abdi-Dezfuli, F; Gislason, H; Svanes, K; Sørbye, H; Waldum, HL | 1 |
| Anbar, RD; Becker, JM; Melvin, JJ | 1 |
| Bousquet, J; Cougnard, J; Czarlewski, W; Danzig, M; Michel, FB | 1 |
| Guo, J; Schofield, GG | 1 |
| ALVAREZ GUIN, M; LANDA BACALLAO, M; VALERDE MARTIN, A | 1 |
| Chies, AB; Ellinger, F; Pereira, OC; Rodrigues, AD; Rossignoli, Pde S; Tinti, T | 1 |
| Camacho, J; García-Quiroz, J | 1 |
| Bhardwaj, M; Jakhar, R; Kang, SC; Paul, S | 1 |
2 review(s) available for astemizole and histamine
| Article | Year |
|---|---|
Antihistamines.
Topics: Animals; Astemizole; Benzhydryl Compounds; Benzimidazoles; Child; Child, Preschool; Cimetidine; Drug Synergism; Guanidines; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Infant; Infant, Newborn; Kinetics; Pyrimidinones; Ranitidine; Terfenadine | 1986 |
Astemizole: an old anti-histamine as a new promising anti-cancer drug.
Topics: Antineoplastic Agents; Astemizole; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Ether-A-Go-Go Potassium Channels; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Neoplasms | 2011 |
9 trial(s) available for astemizole and histamine
| Article | Year |
|---|---|
Single-dose effect of astemizole on bronchoconstriction induced by histamine in asthmatic subjects.
Topics: Adult; Aged; Astemizole; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Female; Forced Expiratory Volume; Histamine; Humans; Male; Methacholine Chloride; Middle Aged; Skin Tests; Vital Capacity | 1992 |
The effects of astemizole, cetirizine and loratadine on the time course of weal and flare reactions to histamine, codeine and antigen.
Topics: Adult; Animals; Antigens; Astemizole; Cetirizine; Codeine; Cyproheptadine; Dermatitis, Contact; Dust; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Middle Aged; Mites; Skin; Time Factors | 1991 |
Duration of the effect of astemizole on histamine-inhalation tests.
Topics: Administration, Inhalation; Adult; Aged; Astemizole; Asthma; Benzimidazoles; Bronchial Provocation Tests; Double-Blind Method; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Male; Methacholine Chloride; Methacholine Compounds; Middle Aged; Peak Expiratory Flow Rate; Random Allocation; Skin Tests; Vital Capacity | 1990 |
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects.
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Placebos; Skin Tests; Terfenadine; Time Factors; Urticaria | 1990 |
The role of histamine in allergen and adenosine-induced bronchoconstriction.
Topics: Adenosine Monophosphate; Allergens; Astemizole; Benzhydryl Compounds; Benzimidazoles; Bronchial Provocation Tests; Bronchial Spasm; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Terfenadine | 1987 |
Blocking of histamine-induced conjunctivitis by the oral antihistamine, astemizole.
Topics: Administration, Oral; Adult; Astemizole; Benzimidazoles; Conjunctivitis; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans | 1988 |
Comparison of the suppressive effect of astemizole, terfenadine, and hydroxyzine on histamine-induced wheals and flares in humans.
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Dose-Response Relationship, Immunologic; Double-Blind Method; Female; Histamine; Humans; Hydroxyzine; Hypersensitivity, Immediate; Immunosuppressive Agents; Male; Skin Tests; Terfenadine | 1986 |
H1-receptor-active histamine not sole cause of chronic idiopathic urticaria.
Topics: Astemizole; Benzimidazoles; Chronic Disease; Histamine; Histamine H1 Antagonists; Humans; Urticaria | 1984 |
Changes in skin-test reactivity do not correlate with clinical efficacy of H1-blockers in seasonal allergic rhinitis.
Topics: Adolescent; Adult; Allergens; Astemizole; Child; Conjunctiva; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Nose; Rhinitis, Allergic, Seasonal; Skin Tests; Treatment Outcome | 1998 |
19 other study(ies) available for astemizole and histamine
| Article | Year |
|---|---|
Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.
Topics: Animals; Antimalarials; Drug Resistance, Multiple; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Neuropathic pain behavior in rats depends on the afferent input from nerve-end neuroma including histamine-sensitive C-fibers.
Topics: Animals; Astemizole; Behavior, Animal; Histamine; Histamine H1 Antagonists; Male; Nerve Endings; Nerve Fibers; Nervous System Neoplasms; Neuroma; Neurons, Afferent; Pain; Rats; Rats, Inbred Strains; Sciatic Nerve | 1991 |
Start and end of the effects of terfenadine and astemizole on histamine-induced wheals in human skin.
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Skin; Skin Tests; Terfenadine; Time Factors | 1989 |
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine.
Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; Cats; Chlorpheniramine; Diphenhydramine; Electroencephalography; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Kinetics; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Oxazepines; Piperazines; Promethazine; Pyrilamine; Terfenadine; Yohimbine | 1989 |
Astemizole and other H1-antihistaminic drug treatment of asthma.
Topics: Astemizole; Asthma; Benzimidazoles; Bronchial Provocation Tests; Bronchial Spasm; Histamine; Histamine H1 Antagonists; Humans; Mast Cells | 1985 |
New antihistaminic N-heterocyclic 4-piperidinamines. 2. Synthesis and antihistaminic activity of 1-[(4-fluorophenyl)methyl]-N-(4-piperidinyl)-1H-benzimidazol-2-a mines.
Topics: Administration, Oral; Animals; Astemizole; Benzimidazoles; Chemical Phenomena; Chemistry; Guinea Pigs; Histamine; Histamine Antagonists; Male; p-Methoxy-N-methylphenethylamine; Piperidines; Pupil; Rats; Rats, Inbred Strains; Serotonin; Skin Tests; Structure-Activity Relationship | 1985 |
New antihistaminic N-heterocyclic 4-piperidinamines. 3. Synthesis and antihistaminic activity of N-(4-piperidinyl)-3H-imidazo[4,5-b]pyridin-2-amines.
Topics: Administration, Oral; Aminopyridines; Animals; Astemizole; Benzimidazoles; Guinea Pigs; Histamine; Histamine Antagonists; Imidazoles; Male; p-Methoxy-N-methylphenethylamine; Piperidines; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1985 |
In vivo pharmacology of astemizole, a new type of H1-antihistaminic compound.
Topics: Animals; Astemizole; Benzimidazoles; Bronchi; Dogs; Drug Interactions; Guinea Pigs; Histamine; Histamine H1 Antagonists; Mice; Mydriatics; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Rats; Skin Tests | 1981 |
Effect of astemizol on mammary blood flow and milk composition after intramammary histamine infusion.
Topics: Animals; Astemizole; Benzimidazoles; Female; Goats; Histamine; Histamine H1 Antagonists; Infusions, Parenteral; Mammary Glands, Animal; Milk | 1983 |
Effect of the histamine-H1 antagonist astemizole on bronchoconstriction in the guinea-pig.
Topics: Animals; Astemizole; Benzimidazoles; Bronchi; Guinea Pigs; Histamine; Histamine H1 Antagonists | 1983 |
The effects of astemizole on histamine-induced weal and flare.
Topics: Adult; Aged; Astemizole; Benzimidazoles; Drug Hypersensitivity; Drug Interactions; Female; Histamine; Histamine H2 Antagonists; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Male; Middle Aged; Pruritus; Urticaria | 1983 |
Role of prostaglandins and histamine in hyperemic response to superficial and deep gastric mucosal injury and H+ back-diffusion in cats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Astemizole; Cats; Dinoprostone; Gastric Acid; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Hyperemia; Indomethacin; Male; Prostaglandins; Regional Blood Flow; Saline Solution, Hypertonic; Triazoles | 1995 |
Does the histamine skin prick test identify patients at risk for toxicity after the ingestion of astemizole?
Topics: Astemizole; Child, Preschool; Dose-Response Relationship, Drug; Female; Histamine; Humans; Intradermal Tests; Poisoning | 1994 |
Histamine inhibits KCNQ2/KCNQ3 channel current via recombinant histamine H(1) receptors.
Topics: Astemizole; Cell Line; Electric Conductivity; HeLa Cells; Histamine; Histamine H1 Antagonists; Humans; Ion Channels; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Osmolar Concentration; Potassium Channels; Potassium Channels, Voltage-Gated; Receptors, Histamine H1; Recombinant Proteins | 2002 |
[Pharmacodynamic action of histamino-salicylic iontophoresis on the adrenals, in rheumatism].
Topics: Adrenal Glands; Astemizole; Histamine; Ion Exchange; Iontophoresis; Rheumatic Diseases; Salicylates; Salicylic Acid | 1955 |
The possible involvement of hyperpolarizing mechanisms in histamine-induced relaxation of the rat portal vein.
Topics: Animals; Astemizole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Histamine; Histamine Agonists; Histamine H1 Antagonists, Non-Sedating; Male; Models, Animal; NG-Nitroarginine Methyl Ester; Phenylephrine; Portal Vein; Potassium Chloride; Rats; Rats, Wistar; Receptors, Histamine H1; Vasoconstrictor Agents; Vasodilation | 2008 |
Astemizole-Histamine induces Beclin-1-independent autophagy by targeting p53-dependent crosstalk between autophagy and apoptosis.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Astemizole; Autophagy; Beclin-1; Breast Neoplasms; Caspases; Endoplasmic Reticulum Stress; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; JNK Mitogen-Activated Protein Kinases; MCF-7 Cells; Membrane Proteins; Microtubule-Associated Proteins; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; RNA Interference; Sequestosome-1 Protein; Signal Transduction; Transfection; Tumor Suppressor Protein p53 | 2016 |