aspirin and valproic acid

aspirin has been researched along with valproic acid in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (17.31)	18.7374
1990's	7 (13.46)	18.2507
2000's	18 (34.62)	29.6817
2010's	16 (30.77)	24.3611
2020's	2 (3.85)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Pisani, F	1
Keller, BJ; Thurman, RG; Yamanaka, H	1
Garcia de la Serrana, H; Mota, C; Puche, E; Saucedo, R	1
Glötzner, FL; Lorz, U	1
Abbott, FS; Farrell, K; Kassam, J; Orr, JM	1
Camfield, PR; Dooley, JM; Fraser, AD; Goulden, KJ	1
Kolts, BE; Langfitt, M	1
Berlin, CM	1
Holtzman, JL	1
Abbott, FS; Farrell, K; Ferguson, S; Godolphin, W; Orr, JM; Sheppard, I	1
Abbott, FS; Bruni, J; Farrell, K; Ferguson, S; Godolphin, W; Orr, JM; Sheppard, I	1
Goadsby, PJ; Kaube, H	1
Guieu, R; Kopeyan, C; Rochat, H	1
Lemasters, JJ; Trost, LC	1
Annoni, JM; Higelin, F	1
Cartigny, B; Imbenotte, M; Lhermitte, M; Vermeersch, G	1
Gupta, YK; Srivastava, AK	1
Imataka, G; Yamanouchi, H	1
Bethke, F; Droste, DW; Flöel, A; Imai, T; Lohmann, H; Sunderkötter, C	1
Gejyo, F; In, H; Ito, S; Izumi, J; Kanazawa, M; Nakano, M; Ohno, T; Tanaka, H; Ueno, M; Wada, Y; Yahata, K	1
Diener, HC; Leniger, T; Limmroth, V; Pageler, L; Stude, P	1
Dyszkiewicz-Korpanty, AM; Frenkel, EP; Sarode, R	1
Arakawa, Y; Hashimoto, N; Kikuta, K; Miyamoto, S; Takagi, Y	1
Bourke, DL; Marcucci, C; Sandson, NB; Smith-Lamacchia, R	1
Altinoz, MA; Carin, MN; Gedikoglu, G; Ozdilli, K	1
Penot, JP; Pradeau, F	1
de Leon, J; Fleming, MW; Kiesel, JL; Strobl, B	1
Aissi, M; Boughammoura-Bouatay, A; Frih-Ayed, M; Jerbi-Ommezzine, S; Sfar, MH; Younes-Mhenni, S	1
Bonomi, A; Cavicchini, L; Ciusani, E; Coccè, V; Gribaldo, L; Pessina, A; Sisto, F	1
Dubuisson, N; Dupuis, F; Dupuis, M; Evrard, F; van Rijckevorsel, K; Van Robays, P	1
Cheng, KW; Constantinides, PP; Rigas, B; Wong, CC; Xie, G; Zhou, D; Zhu, CH	1
Chen, Y; He, H; Li, X; Lou, L; Wang, J; Ye, W; Zhu, Y	1
Cooley, AT; de Leon, J; Riesselman, A; Strobl, B	1
Liu, L; Qu, X; Wang, P; Wang, X; Zeng, H; Zhu, H; Zhu, X	1
Batchelor, LK; Biancalana, L; Bortoluzzi, M; Dyson, PJ; Funaioli, T; Marchetti, F; Pampaloni, G; Zacchini, S	1
Araujo, M; Benevent, J; Damase-Michel, C; Durrieu, G; Foch, C; Lacroix, I; Montastruc, JL; Weckel, A	1
Fasbender, F; Hengstler, JG; Metzler, S; Obholzer, M; Stöber, R; Watzl, C	1

Reviews

7 review(s) available for aspirin and valproic acid

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Influence of co-medication on the metabolism of valproate. Pharmaceutisch weekblad. Scientific edition, 1992, Jun-19, Volume: 14, Issue:3A Topics: Anticonvulsants; Aspirin; Biotransformation; Drug Interactions; Humans; Liver; Oxidation-Reduction; Valproic Acid	1992
Advances in pediatric pharmacology and toxicology. Advances in pediatrics, 1983, Volume: 30 Topics: Animals; Anti-Bacterial Agents; Aspirin; Attention Deficit Disorder with Hyperactivity; Biological Availability; Child; Child, Preschool; Female; Fetus; Humans; Infant; Infant, Newborn; Kinetics; Maternal-Fetal Exchange; Metoclopramide; Otitis Media; Otitis Media with Effusion; Pediatrics; Pharmaceutical Preparations; Pharmacology; Phenobarbital; Pregnancy; Reye Syndrome; Salamandridae; Seizures; Tourette Syndrome; Toxicology; Valproic Acid	1983
Medical treatment of migraine: from mechanisms of action to contraindications. Schweizerische medizinische Wochenschrift, 1998, Mar-07, Volume: 128, Issue:10 Topics: Acetaminophen; Adrenergic beta-Antagonists; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium Channel Blockers; Female; Humans; Male; Migraine Disorders; Serotonin Receptor Agonists; Valproic Acid	1998
[Mitochondrial diseases due to drug toxicity]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 4 Topics: Animals; Antibiotics, Antineoplastic; Aspirin; Humans; Mitochondria; Mitochondrial Diseases; Reye Syndrome; Valproic Acid	2002
Takotsubo syndrome (TKS): a possible mechanism of sudden unexplained death in epilepsy (SUDEP). Seizure, 2012, Volume: 21, Issue:1 Topics: Adrenergic beta-1 Receptor Antagonists; Anticonvulsants; Aspirin; Bisoprolol; Death, Sudden; Epilepsy; Female; Fibrinolytic Agents; Humans; Lamotrigine; Middle Aged; Perindopril; Takotsubo Cardiomyopathy; Triazines; Valproic Acid	2012

Trials

1 trial(s) available for aspirin and valproic acid

Article	Year
Comparison of intravenous valproate with intravenous lysine-acetylsalicylic acid in acute migraine attacks. Headache, 2005, Volume: 45, Issue:1 Topics: Acute Disease; Analgesics; Aspirin; Double-Blind Method; GABA Agents; Humans; Infusions, Intravenous; Lysine; Migraine Disorders; Treatment Outcome; Valproic Acid	2005

Other Studies

44 other study(ies) available for aspirin and valproic acid

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Inhibition of mitochondrial respiration and oxygen-dependent hepatotoxicity by six structurally dissimilar peroxisomal proliferating agents. Toxicology, 1992, Volume: 71, Issue:1-2 Topics: Animals; Aspirin; Cell Division; Clofibrate; Clofibric Acid; Dose-Response Relationship, Drug; Female; Fibric Acids; Hypolipidemic Agents; L-Lactate Dehydrogenase; Microbodies; Mitochondria, Liver; Oxygen Consumption; Rats; Rats, Inbred Strains; Trypan Blue; Valproic Acid	1992
Serum aspirin-esterase activity in epileptic patients receiving treatment with phenobarbital, phenytoin, carbamazepine and valproic acid. International journal of clinical pharmacology research, 1989, Volume: 9, Issue:1 Topics: Adult; Anticonvulsants; Aspirin; Carbamazepine; Epilepsy; Esterases; Female; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid	1989
[Reye syndrome treated with valproic acid in association with varicella infection]. Der Nervenarzt, 1989, Volume: 60, Issue:5 Topics: Adult; Aspirin; Carbamazepine; Chickenpox; Drug Therapy, Combination; Epilepsy; Humans; Male; Reye Syndrome; Risk Factors; Valproic Acid	1989
The effect of aspirin on valproic acid metabolism. Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:1 Topics: Adolescent; Adult; Aspirin; Child; Child, Preschool; Drug Interactions; Gas Chromatography-Mass Spectrometry; Humans; Male; Valproic Acid	1986
Clinical valproate toxicity induced by acetylsalicylic acid. Neurology, 1987, Volume: 37, Issue:8 Topics: Adolescent; Aspirin; Child; Child, Preschool; Drug Interactions; Epilepsy, Temporal Lobe; Female; Humans; Hyperkinesis; Male; Nystagmus, Pathologic; Paranoid Disorders; Tremor; Valproic Acid	1987
Drugs and the liver. Comprehensive therapy, 1984, Volume: 10, Issue:12 Topics: Acetaminophen; Adult; Aspirin; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Cholestasis; Cimetidine; Fatty Liver; Female; Hepatic Artery; Hepatic Veins; Humans; Ketoconazole; Liver; Liver Diseases; Liver Neoplasms; Methyldopa; Necrosis; Nitrofurantoin; Peliosis Hepatis; Portal Vein; Valproic Acid; Verapamil	1984
Definition and implications of dose-dependent kinetics in clinical medicine. Drug metabolism reviews, 1983, Volume: 14, Issue:6 Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Ethanol; Humans; Kinetics; Lidocaine; Pharmaceutical Preparations; Phenytoin; Valproic Acid	1983
Interaction between valproic acid and aspirin in epileptic children: serum protein binding and metabolic effects. Clinical pharmacology and therapeutics, 1982, Volume: 31, Issue:5 Topics: Aspirin; Blood Proteins; Child; Child, Preschool; Drug Interactions; Epilepsy; Female; Humans; Kinetics; Male; Protein Binding; Salicylates; Valproic Acid	1982
The effect of acetylsalicylic acid on serum free valproate concentrations and valproate clearance in children. The Journal of pediatrics, 1982, Volume: 101, Issue:1 Topics: Administration, Oral; Adolescent; Aspirin; Child; Child, Preschool; Humans; Protein Binding; Valproic Acid	1982
Anti-migraine compounds fail to modulate the propagation of cortical spreading depression in the cat. European neurology, 1994, Volume: 34, Issue:1 Topics: Analgesics; Animals; Aspirin; Cats; Cerebral Cortex; Clonazepam; Cortical Spreading Depression; Dihydroergotamine; Dizocilpine Maleate; Female; Halothane; Lidocaine; Metoprolol; Migraine Disorders; Receptors, N-Methyl-D-Aspartate; Regional Blood Flow; Ultrasonography, Doppler, Transcranial; Valproic Acid	1994
Utilization of aspirin, quinine and verapamil in the prevention and treatment of scorpion venom intoxication. Life sciences, 1993, Volume: 53, Issue:26 Topics: Animals; Aspirin; Female; gamma-Aminobutyric Acid; Lethal Dose 50; Mice; Mice, Inbred C57BL; Poisoning; Quinine; Scorpion Venoms; Valproic Acid; Verapamil	1993
The mitochondrial permeability transition: a new pathophysiological mechanism for Reye's syndrome and toxic liver injury. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3 Topics: Animals; Aspirin; Carboxylic Acids; Chemical and Drug Induced Liver Injury; Cyclosporine; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Rats; Rats, Sprague-Dawley; Reye Syndrome; Ruthenium Red; Structure-Activity Relationship; Valproic Acid	1996
[Identification and quantification of exogenous metabolites in biological liquids with new development in NMR spectroscopy in one and two dimensions]. Acta clinica Belgica, 1999, Volume: 53 Suppl 1 Topics: Adolescent; Adult; Analgesics; Anticonvulsants; Antimalarials; Aspirin; Chloroquine; Female; Humans; Lysine; Magnetic Resonance Spectroscopy; Male; Poisoning; Reproducibility of Results; Valproic Acid	1999
Aspirin modulates the anticonvulsant effect of diazepam and sodium valproate in pentylenetetrazole and maximal electroshock induced seizures in mice. Indian journal of physiology and pharmacology, 2001, Volume: 45, Issue:4 Topics: Animals; Anticonvulsants; Aspirin; Diazepam; Male; Mice; Pentylenetetrazole; Prostaglandins; Seizures; Valproic Acid	2001
Therapy of Sneddon syndrome. European neurology, 2002, Volume: 48, Issue:3 Topics: Adult; Antibodies, Antiphospholipid; Anticonvulsants; Aspirin; Azathioprine; Clopidogrel; Drug Therapy, Combination; Epilepsy; Female; Humans; Immunosuppressive Agents; Platelet Aggregation Inhibitors; Sneddon Syndrome; Ticlopidine; Valproic Acid	2002
Mixed connective tissue disease associated with antineutrophil cytoplasmic antibodies against proteinase-3 and systemic atherosclerosis: a case report. Clinical rheumatology, 2004, Volume: 23, Issue:5 Topics: Antibodies, Antineutrophil Cytoplasmic; Arteriosclerosis; Aspirin; Autoantibodies; Cholesterol, LDL; Female; Granulomatosis with Polyangiitis; Humans; Lipid Peroxidation; Malondialdehyde; Middle Aged; Mixed Connective Tissue Disease; Myeloblastin; Prednisolone; Probucol; Serine Endopeptidases; Treatment Outcome; Valproic Acid	2004
Approach to the assessment of platelet function: comparison between optical-based platelet-rich plasma and impedance-based whole blood platelet aggregation methods. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2005, Volume: 11, Issue:1 Topics: Adolescent; Adult; Aspirin; Blood Platelets; Child; Clopidogrel; Diagnostic Tests, Routine; Electric Impedance; Humans; Male; Middle Aged; Plasma; Platelet Aggregation; Platelet Aggregation Inhibitors; Sensitivity and Specificity; Ticlopidine; Valproic Acid	2005
Absence epilepsy associated with moyamoya disease. Case report. Journal of neurosurgery, 2006, Volume: 104, Issue:4 Suppl Topics: Anticonvulsants; Aspirin; Carotid Artery, Internal; Carotid Stenosis; Cerebral Angiography; Cerebral Infarction; Cerebral Revascularization; Child; Child, Preschool; Combined Modality Therapy; Drug Resistance; Electroencephalography; Epilepsy, Absence; Female; Follow-Up Studies; Frontal Lobe; Humans; Moyamoya Disease; Postoperative Complications; Tomography, Emission-Computed, Single-Photon; Valproic Acid	2006
An interaction between aspirin and valproate: the relevance of plasma protein displacement drug-drug interactions. The American journal of psychiatry, 2006, Volume: 163, Issue:11 Topics: Aged; Anticonvulsants; Aspirin; Blood Proteins; Dizziness; Drug Interactions; Drug Monitoring; Humans; Male; Valproic Acid	2006
Medroxyprogesterone - valproic acid - aspirin. MVA regime to reduce transfusion associated mortality in late-term hemoglobinopathies. Hypothesis and rationale. Medical hypotheses, 2007, Volume: 68, Issue:6 Topics: Aspirin; Blood Transfusion, Intrauterine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hemoglobinopathies; Humans; Medroxyprogesterone; Models, Biological; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Trimester, Third; Valproic Acid	2007
[Iatrogenic dementia and extrapyramidal syndrome: rare adverse effect of valproic acid-aspirin combination]. Presse medicale (Paris, France : 1983), 2010, Volume: 39, Issue:2 Topics: Aged; Anticonvulsants; Aspirin; Basal Ganglia Diseases; Dementia; Drug Interactions; Drug Therapy, Combination; Humans; Iatrogenic Disease; Male; Platelet Aggregation Inhibitors; Rare Diseases; Valproic Acid	2010
Valproic acid toxicity associated with low dose of aspirin and low total valproic acid levels: a case report. Journal of clinical psychopharmacology, 2009, Volume: 29, Issue:5 Topics: Aspirin; Dose-Response Relationship, Drug; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Middle Aged; Protein Binding; Seizures; Valproic Acid	2009
[Tuberous sclerosis and intracranial aneurysms: a rare association]. Revue neurologique, 2010, Volume: 166, Issue:11 Topics: Adult; Anticonvulsants; Aspirin; Carbamazepine; Carotid Artery Diseases; Humans; Intracranial Aneurysm; Magnetic Resonance Imaging; Male; Platelet Aggregation Inhibitors; Tuberous Sclerosis; Valproic Acid	2010
A mesenchymal stromal cell line resistant to paclitaxel that spontaneously differentiates into osteoblast-like cells. Cell biology and toxicology, 2011, Volume: 27, Issue:3 Topics: Adipocytes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Aspirin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Cells; Cell Cycle; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Chondrocytes; Drug Resistance, Neoplasm; Female; Humans; Indomethacin; Mesenchymal Stem Cells; Mice; Osteoblasts; Paclitaxel; Valproic Acid	2011
Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Line, Tumor; Cell Survival; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Female; HEK293 Cells; Humans; Hydrolysis; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Kinetics; Mice; Mice, Inbred BALB C; Mice, Nude; Naproxen; Nitrophenols; Organophosphates; Organophosphorus Compounds; Phenylglyoxal; Stomach Neoplasms; Sulindac; Transfection; Valproic Acid; Xenograft Model Antitumor Assays	2012
Synergistically killing activity of aspirin and histone deacetylase inhibitor valproic acid (VPA) on hepatocellular cancer cells. Biochemical and biophysical research communications, 2013, Jun-28, Volume: 436, Issue:2 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Aspirin; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Survival; Drug Synergism; Gene Expression; Hep G2 Cells; Histone Deacetylase Inhibitors; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Reverse Transcriptase Polymerase Chain Reaction; Tumor Burden; Valproic Acid; Xenograft Model Antitumor Assays	2013
A case report that suggested that aspirin's effects on valproic acid metabolism may contribute to valproic acid's inducer effects on clozapine metabolism. Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:6 Topics: Adult; Antimanic Agents; Antipsychotic Agents; Aspirin; Bipolar Disorder; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Valproic Acid	2013
As2O3 synergistically reactivate latent HIV-1 by induction of NF-κB. Antiviral research, 2013, Volume: 100, Issue:3 Topics: Arsenic Trioxide; Arsenicals; Aspirin; Cells, Cultured; Dose-Response Relationship, Drug; Genes, Reporter; HEK293 Cells; HIV Long Terminal Repeat; HIV-1; Humans; Jurkat Cells; Leukocytes, Mononuclear; Microscopy, Fluorescence; NF-kappa B; Oxides; Phorbol Esters; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha; Valproic Acid; Virus Activation; Virus Latency	2013
α-Diimines as Versatile, Derivatizable Ligands in Ruthenium(II) p-Cymene Anticancer Complexes. Inorganic chemistry, 2018, Jun-04, Volume: 57, Issue:11 Topics: Antineoplastic Agents; Aspirin; Cell Line, Tumor; Cisplatin; Coordination Complexes; Cymenes; Drug Stability; Electrochemical Techniques; Humans; Imines; Ligands; Models, Chemical; Monoterpenes; Quantum Theory; Ruthenium; Solubility; Valproic Acid; Water	2018
In utero drug exposure and hearing impairment in 2-year-old children A case-control study using the EFEMERIS database. International journal of pediatric otorhinolaryngology, 2018, Volume: 113 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Aspirin; Case-Control Studies; Child, Preschool; Databases, Factual; Female; France; Glucocorticoids; Hearing Loss; Humans; Male; Otitis Media; Pregnancy; Prenatal Exposure Delayed Effects; Valproic Acid	2018
Enhanced activation of human NK cells by drug-exposed hepatocytes. Archives of toxicology, 2020, Volume: 94, Issue:2 Topics: Antibodies, Neutralizing; Aspirin; Chemical and Drug Induced Liver Injury; Coculture Techniques; Cytotoxicity Tests, Immunologic; Gene Expression Regulation; Hepatocytes; Histocompatibility Antigens Class I; Humans; Interferon-gamma; Isoniazid; Ketoconazole; Killer Cells, Natural; Natural Cytotoxicity Triggering Receptor 3; NK Cell Lectin-Like Receptor Subfamily K; Valproic Acid	2020