aspirin and troglitazone

aspirin has been researched along with troglitazone in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's13 (81.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barreiro, EJ; Fraga, CA; Lima, LM; Romeiro, NC; Sant'Anna, CM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Ahn, S; An, S; Hwang, J; Hyun, S; Lee, J; Lee, M; Noh, M1
Ahn, S; An, S; Choi, H; Han, Y; Jin, SH; Kim, HJ; Kim, SO; Kim, YJ; Noh, M; Park, NH; Rho, HS; Shin, JC1
Menzel, J; Sobal, G1
Chang, HY; Cheng, AL; Chuang, SE; Lai, GM; Yan, KH; Yao, CJ1
Fujino, H; Kato, T; Kawashima, T; Murayama, T; Oyama, S1
Hirasawa, N; Kotake, D1
Chang, JH; Jaochico, A; Liu, N; Plise, E; Sangaraju, D1

Reviews

1 review(s) available for aspirin and troglitazone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for aspirin and troglitazone

ArticleYear
NSAIDs revisited: putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARgamma).
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalytic Domain; Computational Biology; Drug Design; Ligands; Models, Molecular; PPAR gamma; Protein Conformation; Software

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
2-Formyl-komarovicine promotes adiponectin production in human mesenchymal stem cells through PPARγ partial agonism.
    Bioorganic & medicinal chemistry, 2018, 03-01, Volume: 26, Issue:5

    Topics: Adipogenesis; Adiponectin; Binding Sites; Bone Marrow Cells; Cell Line; Chromans; Fluorescence Resonance Energy Transfer; Humans; Indoles; Ligands; Mesenchymal Stem Cells; Molecular Docking Simulation; PPAR gamma; Protein Binding; Protein Structure, Tertiary; Pyridines; Quinolines; Thiazolidinediones; Troglitazone

2018
Kojyl cinnamate esters are peroxisome proliferator-activated receptor α/γ dual agonists.
    Bioorganic & medicinal chemistry, 2018, 11-15, Volume: 26, Issue:21

    Topics: Adipogenesis; Adiponectin; Cinnamates; Dinoprostone; Humans; Inflammation; Keratinocytes; Matrix Metalloproteinase 1; Mesenchymal Stem Cells; Molecular Docking Simulation; Molecular Structure; PPAR alpha; PPAR gamma; Pyrones; RNA, Messenger; Up-Regulation

2018
The role of antioxidants in the long-term glycation of low density lipoprotein and its Cu2+-catalyzed oxidation.
    Free radical research, 2000, Volume: 32, Issue:5

    Topics: Antioxidants; Aspirin; Chromans; Copper; Edetic Acid; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Humans; Lipoproteins, LDL; Oxidation-Reduction; Spectrometry, Fluorescence; Thiazoles; Thiazolidinediones; Troglitazone; Vitamin E

2000
The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells.
    Molecular carcinogenesis, 2010, Volume: 49, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Aspirin; Blotting, Western; Cell Cycle; Cell Proliferation; Chromans; Colony-Forming Units Assay; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; Humans; Lung Neoplasms; Poly(ADP-ribose) Polymerases; PPAR gamma; Thiazolidinediones; Troglitazone; Tumor Cells, Cultured

2010
Indomethacin induces cellular morphological change and migration via epithelial-mesenchymal transition in A549 human lung cancer cells: a novel cyclooxygenase-inhibition-independent effect.
    Biochemical pharmacology, 2011, Dec-01, Volume: 82, Issue:11

    Topics: Anticarcinogenic Agents; Aspirin; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromans; Collagen Type IV; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Epithelial-Mesenchymal Transition; Humans; Indomethacin; Lung Neoplasms; Matrix Metalloproteinase 9; PPAR gamma; Thiazolidinediones; Troglitazone

2011
Activation of a retinoic acid receptor pathway by thiazolidinediones induces production of vascular endothelial growth factor/vascular permeability factor in OP9 adipocytes.
    European journal of pharmacology, 2013, May-05, Volume: 707, Issue:1-3

    Topics: Adipocytes; Animals; Aspirin; Capillary Permeability; Cell Differentiation; Cells, Cultured; Chromans; Edema; Gene Expression Regulation; Guinea Pigs; Hypoglycemic Agents; Indomethacin; Male; Mice; PPAR gamma; Receptors, Retinoic Acid; Thiazolidinediones; Troglitazone; Vascular Endothelial Growth Factor A

2013
Comprehensive Evaluation of Bile Acid Homeostasis in Human Hepatocyte Co-Culture in the Presence of Troglitazone, Pioglitazone, and Acetylsalicylic Acid.
    Molecular pharmaceutics, 2019, 10-07, Volume: 16, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bile Acids and Salts; Cells, Cultured; Chemical and Drug Induced Liver Injury; Coculture Techniques; Hepatocytes; Homeostasis; Humans; Hypoglycemic Agents; Pioglitazone; Troglitazone

2019