aspirin has been researched along with thromboxanes in 383 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 212 (55.35) | 18.7374 |
| 1990's | 65 (16.97) | 18.2507 |
| 2000's | 58 (15.14) | 29.6817 |
| 2010's | 34 (8.88) | 24.3611 |
| 2020's | 14 (3.66) | 2.80 |
| Authors | Studies |
|---|---|
| Vargaftig, BB | 1 |
| Foegh, M | 1 |
| de Gaetano, G; Livio, M; Villa, S | 1 |
| Johnson, MC; Kelly, JP; Parker, CW | 1 |
| Burch, JW; Majerus, PW | 1 |
| Parker, CW | 1 |
| Marcus, AJ | 1 |
| Kam, ST; Portoghese, PS | 1 |
| Moncada, S; Vane, JR | 3 |
| Dmoszyńska-Giannopoulou, A; Kowalewski, J | 1 |
| Basista, M; Dobranowski, J; Gryglewski, RJ | 1 |
| Korbut, R; Moncada, S | 1 |
| Katler, E; Weissmann, G | 1 |
| Gingrich, RD; Hoak, JC | 1 |
| Ahnfelt-Rønne, I; Arrigoni-Martelli, E | 1 |
| Amezcua, JL; Moncada, S | 1 |
| McGiff, JC | 1 |
| Vane, JR | 1 |
| Addonizio, VP; Colman, RW; Edmunds, LH; Guiod, LR; Smith, JB; Strauss, JF | 1 |
| Grant, B; Katz, J; Lindner, C; Meyers, KM | 1 |
| Grodzińska, L; Gryglewski, RJ; Marcinkiewicz, E; Musiał, J; Serwońska, M; Szczeklik, A | 1 |
| Chang, WC; Murota, SI; Tsurufuji, S | 1 |
| Shalaev, SV | 1 |
| Diss, EM; Gabbe, SG; Kniss, DA; Moore, JW | 1 |
| Kay, HH; McCoy, MC; Walsh, SW; Wang, Y | 1 |
| Edhag, O; Gréen, K; Henriksson, P; Rasmanis, G; Vesterqvist, O | 2 |
| Beyers, BJ; Longenecker, GL; Mankad, VN | 1 |
| Deckmyn, H; Vermylen, J | 1 |
| Edmondson, SF; Kovacs, IB; Ratnatunga, CP; Rees, GM | 1 |
| Sibai, BM | 1 |
| Aznar, J; Broekman, MJ; Marcus, AJ; Martinez-Sales, V; Portoles, M; Safier, LB; Santos, MT; Valles, J | 1 |
| Chiabrando, C; Fanelli, R; Martelli, L; Rivoltella, L; Valzacchi, S | 1 |
| Jáchymová, M; Knotková, V; Nĕmecek, K; Petrů, I | 1 |
| Beisiegel, B; Darius, H; Erbel, R; Hafner, G; Meyer, J; Pop, T; Rupprecht, HJ; Treese, N | 1 |
| Khosseĭn Shakhavat, AF; Shelest, AN; Shushliapin, OI | 1 |
| Karasawa, A; Kubo, K; Shirakura, S | 1 |
| Bhakdi, S; Eberspächer, B; Grimminger, F; Holland, IB; Hugo, F; Obernitz, R; Seeger, W; Suttorn, N; Thomas, M; Walmrath, D | 1 |
| Bass, TA; Bove, AA; Cowley, M; Goldberg, S; Macdonald, RG; Margolis, JR; Savage, MP; Taussig, AS; Vetrovec, G; Whitworth, HB | 1 |
| Braden, GA; FitzGerald, GA; Knapp, HR | 1 |
| Asai, F; Ito, T; Matsuda, K; Oshima, T; Ushiyama, S | 1 |
| Wallenburg, HC | 1 |
| Force, T; Hibberd, P; Leaf, A; Lorenz, R; Milani, R; Uedelhoven, W; Weber, P | 1 |
| Botting, RM; Vane, JR | 1 |
| Chamberlain, GV; McParland, P; Pearce, JM | 1 |
| Boem, A; Ciabattoni, G; De Caterina, R; Gazzetti, P; Giannessi, D; Patrono, C; Sicari, R | 1 |
| Walsh, SW | 4 |
| Barrow, SE; Cockcroft, JR; Minuz, P; Ritter, JM | 1 |
| Averna, M; Catalano, I; Ciabattoni, G; Davì, G; Notarbartolo, A; Patrono, C; Strano, A | 1 |
| Callingham, BA; Evans, RJ; Nolan, AM | 1 |
| Bachelot, C; Boucheix, C; Hogg, N; Levy-Toledano, S; Rendu, F | 1 |
| Dougan, P; Wieslander, JB | 1 |
| Maderna, P; Paoletti, R; Tremoli, E | 1 |
| Bekemeier, H; Hirschelmann, R | 1 |
| Chenoweth, DE; Engler, RL; Ito, BR; Lefer, AM; Roth, DM | 1 |
| Boehlig, B; Lorenz, RL; Uedelhoven, WM; Weber, PC | 1 |
| Nelson, DM; Walsh, SW | 1 |
| Barrow, SE; Beacham, J; Cockcroft, JR; Doktor, HS; Ritter, JM | 1 |
| Ballerini, S; Benigni, A; Chiabrando, C; Fanelli, R; Frusca, T; Gregorini, G; Orisio, S; Piccinelli, A; Pinciroli, V; Valcamonico, A | 1 |
| Bochner, F; James, MJ; Lloyd, JV; McIntosh, GH; Rodgers, SE; Siebert, DM | 1 |
| Danesh, BJ; Forbes, CD; Lowe, GD; McLaren, M; Russell, RI | 2 |
| McDonald, JW; Smallbone, BW; Taylor, NE | 1 |
| Bryan, C; Butcher, B; Hwang, D; Kadowitz, P; Kumar, P; Leech, SH | 1 |
| Dray, F; Fafeur, V; Gouin, E | 1 |
| Canga, L; Sterin-Borda, L | 1 |
| Khimenko, PL | 1 |
| Vallance, P | 1 |
| Bellucci, S; Maclouf, J | 1 |
| Frishman, WH; Miller, KP | 1 |
| Catella, F; Fitzgerald, DJ; FitzGerald, GA; Lawson, JA | 1 |
| Pillsbury, HC; Poole, MD | 1 |
| Palmer, RM; Salmon, JA | 1 |
| Cerbone, AM; Cirillo, F; Di Minno, G; Mancini, M; Mattioli, PL; Pannain, M; Postiglione, A | 1 |
| Kaliner, MA; Lundgren, JD; Shelhamer, JH | 1 |
| Botha, JH; Leary, WP; Robinson, KM | 1 |
| Hiller, E; Höfling, B; Riess, H; von Arnim, T | 1 |
| Matsuda, T | 1 |
| Parisi, VM; Walsh, SW | 1 |
| Benigni, A; Bertani, T; Carminati, C; Cutillo, F; Morelli, C; Remuzzi, G; Rocchi, G; Verroust, P | 1 |
| Frölich, JC; Küster, LJ | 1 |
| Holmsen, H | 1 |
| Adkinson, NF; Brown, MS; Kagey-Sobotka, A; Lichtenstein, LM; Naclerio, RM; Norman, PS; Peters, SP; Proud, D | 1 |
| Kagawa, K; Kagawa, T; Kasahara, K; Masuda, A; Nonoyama, A; Omoto, K; Sakurai, Y | 1 |
| Lane, I; McCollum, C; Meek, A; Poskitt, K | 1 |
| Szczeklik, A | 1 |
| Patscheke, H; Stegmeier, K | 1 |
| Cerletti, C; de Gaetano, G | 1 |
| Connor, AM; Laposata, M | 1 |
| Bochner, F; Lloyd, JV; Rodgers, SE; Siebert, DM; Sils, D; Wilson, KM | 1 |
| Anttila, M; Kahela, P; Uotila, P | 1 |
| Rao, GH | 1 |
| Catella, F; FitzGerald, GA; Healy, D; Lawson, JA | 1 |
| Badian, MJ; Frölich, JC; Rupp, WA; Zapf, RM | 1 |
| Chernoff, SB; Dujovne, CA; Reynoso, L; Trowbridge, C; Woodroof, J; Zucker, ML | 1 |
| Kääpä, P; Mäkilä, UM; Viinikka, L; Ylikorkala, O | 1 |
| Lecompte, T; Samama, M | 1 |
| Eisert, WG; Eldor, A; Fuks, Z; Muller, TH; Vlodavsky, I | 1 |
| de Groot, PG; Kallmann, R; Nieuwenhuis, HK; Sixma, JJ; van Gijn, J | 1 |
| Buja, LM; Hillis, LD; Willerson, JT; Winniford, M | 1 |
| Gay, WA; Subramanian, VA; Tack-Goldman, K; Weksler, BB | 1 |
| Ito, T; Ogawa, K | 1 |
| Wang, RL; Xu, DC; Xu, LN | 1 |
| Broekman, MJ; Gorman, RR; Islam, N; Marcus, AJ; Oglesby, TD; Safier, LB; Ullman, HL; Ward, JW | 1 |
| James, MJ; Walsh, JA | 1 |
| Katori, M | 1 |
| Guccione, MA; O'Brien, KM; Packham, MA | 1 |
| Colli, S; Maderna, P; Morazzoni, G; Stragliotto, E; Tremoli, E | 1 |
| Atkinson, PM; Bradlow, BA; Chetty, N | 1 |
| Courillon-Mallet, A; Wautier, JL | 1 |
| Dietrich, M; Nawroth, PP; Stern, DM | 1 |
| Bernini, W; De Caterina, R; Donato, L; Filabozzi, P; Gazzetti, P; Giannessi, D; L'Abbate, A; Michelassi, C; Patrignani, P; Patrono, C | 1 |
| Bernini, W; De Caterina, R; Gazzetti, P; Giannessi, D | 1 |
| Cook, JA; Halushka, PV; Loadholt, CB; Reines, HD | 1 |
| Cerletti, C; de Gaetano, G; Dejana, E; Garattini, S; Latini, R; Tognoni, G | 1 |
| Choiniere, L; Cooper, JD; Dubois, P; Egan, TM; McDonald, JW; Saunders, NR | 1 |
| Brace, LD; Fareed, J; Issleib, S | 1 |
| Adams, GA; Feuerstein, IA | 1 |
| D'Angelo, A; Galli, G; Mannucci, PM; Pareti, FI; Sautebin, L; Smith, JB | 1 |
| Bevan, J; Cockbill, SR; Hanley, SP; Heptinstall, S | 1 |
| Allen, PD; Dunham, B; Hechtman, HB; Krausz, MM; Mannick, JA; Shepro, D; Utsunomiya, T | 1 |
| Foegh, ML; Helfrich, GB; Ramwell, PW; Schreiner, GE; Winchester, JF; Zmudka, M | 1 |
| Born, GV; Shafi, S; Thorngren, M | 1 |
| Kotzur, J; Lorenz, RL; Meister, W; Reichardt, B; Schacky, CV; Theisen, K; Weber, M; Weber, PC | 1 |
| Bailey, JM; Bryant, RW; Low, CE; Pupillo, MB; Vanderhoek, JY | 1 |
| Brash, AR; FitzGerald, GA; Lawson, JA; Maas, RL; Oates, JA; Roberts, LJ | 1 |
| Ciabattoni, G; Cinotti, GA; Filabozzi, P; Patrignani, P; Patrono, C; Pierucci, A; Pinca, E; Pugliese, F; Satta, MA; Simonetti, BM; van Dorne, D | 1 |
| Amplatz, K; Bruhlmann, WF; Castaneda, F; Castaneda-Zuniga, WR; Cragg, AH; Einzig, S; Rysavy, JA; Shebuski, RJ; Zollikofer, CL | 1 |
| Salzman, EW; Steer, ML | 1 |
| Köhler, P; Müller, M; Peskar, BA; Rösen, P; Schrör, K | 1 |
| Best, LC; Bone, EA; Graham, R; Russell, G | 1 |
| Bennett, JS; Burch, JW; Vilaire, G | 1 |
| Mahmud, I; Miura, Y | 1 |
| Abbate, R; Galanti, G; Gensini, GF; Laureano, R; Neri Serheri, GG; Paoli, G | 1 |
| Borgeat, P; Picard, S; Roy, S; Sirois, P; Vallerand, P | 1 |
| Jørgensen, KA | 1 |
| Benigni, A; Day, SS; De Gaetano, G; Dodesini, P; Livio, M; Patrignani, P; Patrono, C; Pinca, E; Remuzzi, G; Schieppati, A; Smith, WL | 1 |
| ten Hoor, F | 1 |
| Robinson, DR | 1 |
| Brash, AR; FitzGerald, GA; Hawiger, J; Lawson, JA; Maas, RL; Oates, JA; Roberts, LJ | 1 |
| Cauchie, C | 1 |
| Allen, PD; Hechtman, HB; Krausz, MM; Levine, L; Mannick, JA; McIrvine, AJ; Shepro, D; Utsunomiya, T | 1 |
| Borda, ES; Gimeno, AL; Gimeno, MF; Lazzari, MA; Sterin-Borda, L | 1 |
| Viinikka, L; Ylikorkala, O | 3 |
| Gurewich, V; Louie, S | 1 |
| Kauppila, A; Viinikka, L; Ylikorkala, O | 1 |
| Inoue, T | 1 |
| FitzGerald, GA; Oates, JA | 1 |
| Aguila, E; Lopez, L; Mehta, JL; Mehta, P; Ostrowski, N | 1 |
| Ritter, JM | 1 |
| Dorsch, W; Hintschich, C; Neuhauser, J; Weber, J | 1 |
| Block, HU; Braun, H; Foerster, W; Hoffmann, W; Mest, HJ; Taube, C | 1 |
| Mehta, J; Roberts, A | 1 |
| Lewy, RI | 1 |
| Catalano, PM; De Marco, L; Di Minno, G; Murphy, S; Shapiro, SS | 1 |
| Leid, RW; McConnell, LA | 1 |
| Ali, M; de Kergommeaux, BD; McDonald, JW | 1 |
| Hoak, JC | 1 |
| Custro, N; Davì, G; Mattina, A; Novo, S; Strano, A | 1 |
| Anggård, E | 1 |
| Block, LH; Rhyner, K; Stenger, M | 1 |
| Agozzino, S; Bellavite, O; Donà, GC; Pagella, PG | 1 |
| Lewis, GP; Smith, JR | 1 |
| Dunn, MJ | 1 |
| Campbell, WB; Hillis, LD; Jackson, JA; Rehr, RB; Winniford, MD | 1 |
| Leĭtin, VL; Mazurov, AB; Repin, VS | 1 |
| Förster, W; Leytin, VL; Mazurov, AV; Repin, VS; Taube, C | 1 |
| Butler, RR; Cook, JA; Halushka, PV; Rambo, W; Reines, HD; Wise, WC | 1 |
| Toivanen, J; Viinikka, L; Ylikorkala, O | 1 |
| Gréen, K; Vesterqvist, O | 1 |
| Capodicasa, G; Davì, G; Galione, G; Mazzola, A; Meringolo, C; Orlandi, M; Picone, F; Strano, A; Tomasi, V | 1 |
| Salokannel, J; Viinikka, L; Ylikorkala, O | 1 |
| Deckmyn, H; Van Houtte, E; Vermylen, J; Verstraete, M | 1 |
| Dahl, ML; Uotila, P | 1 |
| Konturek, SJ; Kopp, B; Kwiecień, N; Obtułowicz, W; Oleksy, J; Sito, E | 1 |
| Bach, MK; Bothwell, WM; Creese, BR; Fitzpatrick, FA | 1 |
| Blake, DA; Dubin, NH; Ghodgaonkar, RB | 1 |
| Gordin, A; Lamminsivu, U; Metsä-Ketelä, T; Nuotto, E; Paasonen, MK | 1 |
| Ali, M; Cooper, JD; McDonald, JW; Morgan, E; Townsend, ER | 1 |
| Ali, M; Cragg, DB; Forrest, JB; McDonald, JW; Todd, MH | 1 |
| Cohn, LS; Klotz, TA; Zipser, RD | 1 |
| Miller, JL; Stuart, MJ; Walenga, RW | 1 |
| Almasio, P; Gamba, G; Grignani, G; Pacchiarini, L; Pagliarino, M | 1 |
| Carter, CJ; Kelton, JG; Nguyen, KB; Rosenfeld, J | 1 |
| Maillard, P | 1 |
| Gryglewski, RJ | 1 |
| Cowan, DH | 1 |
| Seale, JP | 1 |
| Bryon, P; Caen, JP; Hardisty, RM; Levy-Toledano, S; Maclouf, J; Savariau, E | 1 |
| Smith, JB; Willis, AL | 1 |
| Patrignani, P; Patrono, C | 1 |
| Nakeff, A; Worthington, RE | 1 |
| Jones, PB; Leach, E; Martin, JF; Suggett, AJ | 1 |
| Badenhorst, PN; Deckmyn, H; Vermylen, J | 1 |
| Crews, F; Horalek, C; Mehta, J; Mehta, P; Ostrowski, N; Roy, L | 1 |
| Bruckner, G; Combs, GF; Infante, J; Kinsella, JE | 1 |
| Harada, Y; Ishibashi, M; Katori, M; Miyazaki, H; Oh-Ishi, S; Tanaka, K; Uchida, Y; Ueno, A; Yamashita, K | 1 |
| Mehta, J; Mehta, P | 1 |
| Araki, H; Lefer, AM; Smith, JB | 1 |
| French, AJ; Jackson, CA; Preston, FE; Stoddard, CJ; Whipps, S; Wyld, PJ | 1 |
| Alexander, RW; Handin, RI | 1 |
| FitzGerald, GA; Friesinger, GC; Maas, RL; Oates, JA; Roberts, LJ; Robertson, D; Robertson, RM | 1 |
| Boyd, J; Eling, T; Korbut, R | 2 |
| Herman, AG | 1 |
| Moncada, S | 1 |
| Kiistala, U; Oikarinen, A; Rytsälä, H; Viinikka, L; Ylikorkala, O | 1 |
| Berti, F; Brunelli, G; Folco, GC; Omini, C; Rossoni, G; Viganò, T | 1 |
| Abbate, R; Gensini, GF; Mannelli, M; Masotti, G; Poggesi, L; Serneri, GG | 1 |
| Bakhle, YS | 1 |
| Castaldi, PA | 1 |
| Filabozzi, P; Patrignani, P; Patrono, C | 1 |
| Verdecchia, P | 1 |
| Addonizio, VP; Feldman, P; Fisher, CA; Harken, AH; Strauss, JF; Wetstein, L | 1 |
| Chierchia, S; Crea, F; de Caterina, R; Maseri, A; Patrono, C | 1 |
| Best, LC; Jones, PB; Russell, RG | 1 |
| Breton-Gorius, J; Chignard, M; Conard, J; Dechavanne, M; Hotchen, M; Lagarde, M; Lecrubier, C; Samama, M; Vargaftig, B | 1 |
| Lorenz, R; Siess, W; Weber, PC | 1 |
| Patscheke, H | 1 |
| Hwang, DH; LeBlanc, P | 1 |
| Gerrard, JM; Rao, GH; White, JG; Witkop, CJ | 1 |
| Coker, SJ; Ledingham, IM; Parratt, JR; Zeitlin, IJ | 1 |
| Abe, H; Fujisawa, A; Imaizumi, M; Kimura, K; Kusunoki, M; Matsumoto, M; Uyama, O; Yoneda, S | 1 |
| Abe, H; Fujisawa, A; Kimura, K; Kusunoki, M; Matsumoto, M; Matsuyama, T; Uyama, O; Yoneda, S | 1 |
| Addonizio, VP; Colman, RW; Edmunds, LH; Smith, JB; Strauss, JF | 1 |
| Harada, Y; Ishibashi, M; Katori, M; Miyazaki, H; Tanaka, K; Yamashita, Y | 1 |
| Ladd, N; Lewis, GP | 1 |
| Castrucci, G; Ciabattoni, G; De Salvo, A; Parachini, M; Patrono, C; Pinca, E; Pugliese, F; Satta, MA | 1 |
| Ali, M; Cerskus, AL; McDonald, JW | 1 |
| Berti, F; Folco, GC; Mandelli, V; Omini, C; Rossoni, G; Vigano, T | 1 |
| Imaizumi, M; Kayama, N; Matsumoto, M; Miyamoto, T; Nukada, T; Uyama, O; Yoneda, S | 1 |
| McManus, LM; Pinckard, RN; Shaw, JO | 1 |
| Barbieri, B; Cerletti, C; de Gaetano, G; Dejana, E; Livio, M | 1 |
| Schrör, K | 1 |
| Balsamo, V; Davì, G; Ganci, A; Giammarresi, C; Iapichino, L; Patrignani, P; Patrono, C | 1 |
| Imura, Y; Kato, K; Kawamura, M; Nishikawa, K; Terashita, Z | 1 |
| Fiscus, RR; Han, C; Jones, SB; Wang, X; Yang, L | 1 |
| Higo, K; Karasawa, A; Shirakura, S; Takeda, M | 1 |
| Grimminger, F; Pilch, J; Scharmann, M; Seeger, W; Walmrath, D | 1 |
| Drobinski, G; Grosgogeat, Y; Maclouf, J; Montalescot, G; Salloum, J; Thomas, D | 1 |
| Coffman, TM; Smith, SR; Svetkey, LP | 1 |
| Cohen, DS; Dotson, R; Mathis, J; Olson, RW; Webb, RL | 1 |
| Alberti, E; Bonollo, M; Chiabrando, C; Djurup, R; Fanelli, R; Rivoltella, L | 1 |
| Andria, G; Catalano, I; Ciabattoni, G; Cirillo, F; Davì, G; Di Minno, G; Grandone, E; Margaglione, M; Patrono, C; Strisciuglio, P | 1 |
| Grimminger, F; König, R; Pilch, J; Scharmann, M; Seeger, W; Walmrath, D | 1 |
| Julkunen, H; Kaaja, R; Viinikka, L; Ylikorkala, O | 1 |
| Belzer, FO; Saunder, A; Schilling, M; Southard, JH | 1 |
| Ciabattoni, G; Rångemark, C; Wennmalm, A | 1 |
| Kalkman, EA; Saxena, PR; Schoemaker, RG; van Dijk, JP; van Suylen, RJ | 1 |
| Habib, A; Karim, S; Lévy-Toledano, S; Maclouf, J | 1 |
| Buring, JE; Hennekens, CH; Lipinska, I; Ridker, PM; Tofler, GH | 1 |
| Aznar, J; Broekman, MJ; Marcus, AJ; Safier, LB; Santos, MT; Valles, J | 1 |
| Walsh, SW; Wang, Y | 1 |
| Förster, W; Parratt, JR | 1 |
| Cole, AT; Filipowicz, B; Hawkey, CJ; Hudson, N; Murray, FE | 1 |
| Alessandri, C; Basili, S; Cipollone, F; Cordova, C; Davì, G; Gazzaniga, P; Santarone, S; Vieri, M; Violi, F | 1 |
| Abramov, D; Boner, G; Erez, E; Erman, A; Raanani, E; Snir, E; Sulkes, J; Vidne, BA | 1 |
| Brunetti, L; Mancuso, S; Marana, R; Margutti, F; Muzii, L; Vacca, M | 1 |
| Eichler, HG; Jilma, B; Kapiotis, S; Pernerstorfer, T; Stohlawetz, P; Stummvoll, G; Szekeres, T | 1 |
| Beckmann, H; Dauben, HP; Elert, O; Gams, E; Keith, PR; Klein, M; Mayer, G; Schulte, HD | 1 |
| Blombäck, M; Fatah, K; Hjemdahl, P; Williams, S | 1 |
| Catella-Lawson, F; Cucchiara, AE; Delanty, N; Lawson, JA; Meagher, E; Moran, N; Reilly, MP | 1 |
| Cirino, G; Del Soldato, P; Dicay, M; McKnight, W; Muscara, MN; Wallace, JL | 1 |
| Corsini, G; Milani, M; Vetrano, A | 1 |
| Bolognese, JA; Harper, SE; Hoover, ME; Lanza, FL; Quan, H; Rack, MF; Simon, TJ; Wilson, FR | 1 |
| Hishinuma, T; Matsumura, E; Mizugaki, M; Murai, Y; Tamai, M; Yamanobe, S; Yamazaki, T | 1 |
| Lanza, FL | 1 |
| Basili, S; Ciabattoni, G; Cipollone, F; Davì, G; Di Franco, M; Ferro, D; Roccaforte, S | 1 |
| Cerletti, C; Evangelista, V; Manarini, S; Patrignani, P; Santini, G; Sciulli, MG | 1 |
| Debili, N; Lazar, V; Letestu, R; Massé, A; Vainchenker, W; Vitrat, N | 1 |
| Hohlfeld, T; Liesener, S; Schanz, A; Schrör, K; Weber, AA | 1 |
| Casonato, A; Deana, R; Francesconi, M; Girolami, A; Scapin, M | 1 |
| Betancourt, J; Cryer, B; Feldman, M; Rushin, K | 1 |
| Gams, E; Hohlfeld, T; Kienzle, P; Schrör, K; Weber, AA; Winter, J; Zimmermann, N | 1 |
| FitzGerald, GA; Narumiya, S | 1 |
| del Soldato , P; Dicay, M; Lovren, F; McKnight, W; Muscará, MN; Triggle, CR; Wallace, JL | 1 |
| Husted, SE; Jensen, HK; Kristensen, SD; Nielsen, HK; Vissinger, H; Ziegler, BK | 1 |
| Affolter, JT; Balment, RJ; Boyd, J; de Haas, SL; Pellegrini, MP; Webb, DJ; Wilkinson, IB; Winter, MJ | 1 |
| Hohlfeld, T; Przytulski, B; Schanz, A; Schrör, K; Weber, AA | 1 |
| Halushka, MK; Halushka, PV | 1 |
| Eikelboom, JW; Hirsh, J; Johnston, M; Weitz, JI; Yi, Q; Yusuf, S | 1 |
| SoRelle, R | 1 |
| Gupta, S | 1 |
| Eikelboom, JW; McQuillan, A | 1 |
| Arrebola, MM; De La Cruz, JP; Escalante, R; Guerrero, A; Sánchez de La Cuesta, F; Villalobos, MA | 1 |
| Altman, R; Rouvier, J; Scazziota, A | 1 |
| Lecompte, T | 1 |
| Bovill, E; Cornell, E; Feinberg, WM; Hart, RG; Leonard, AD; Pearce, LA; Talbert, RL | 1 |
| Bing, RJ; Karouni, K; Lomnicka, M; Sue, M; Wessel, LA | 1 |
| Clarke, R; Harrison, G; Richards, S | 1 |
| Gams, E; Hohlfeld, T; Kienzle, P; Kim, U; Schrör, K; Weber, AA; Wenk, A; Zimmermann, N | 1 |
| Gertz, BJ; Reicin, A; Sperling, RS; Weir, MR | 1 |
| Patrignani, P | 1 |
| Gerrah, R; Izhar, U | 1 |
| Pignatelli, P; Pulcinelli, FM; Violi, F | 1 |
| Dippel, DW; Koudstaal, PJ; Leebeek, FW; Li, SS; Mehicevic, A; Van Kooten, F; van Vliet, HH | 1 |
| Beer, JH | 1 |
| Dorsam, RT; Jin, J; Kim, S; Kunapuli, SP; Murugappan, S; Rachoor, S; Shankar, H | 1 |
| Fitzgerald, DJ; Maree, AO | 1 |
| Gams, E; Hohlfeld, T; Kurt, M; Wenk, A; Winter, J; Zimmermann, N | 1 |
| Cockcroft, JR; Coffey, MJ; Coles, B; Lewis, MJ; Morrow, JD; O'Donnell, VB; Sanchez, S; Williams, PC | 1 |
| Fitzgerald, D; Hjemdahl, P; Perneby, C; Rooney, C; Wallén, NH | 1 |
| Ford, GD; Vaughan, JE; Walsh, SW | 1 |
| Arrebola, MM; Cañada, MJ; De la Cruz, JP; González-Correa, JA; Guerrero, A; Muñoz Marín, J; Sánchez De la Cuesta, F | 1 |
| Dobaczewski, M; Golanski, J; Kazmierczak, P; Lapshina, E; Markuszewski, L; Nocun, M; Watala, C; Zavodnik, I; Zavodnik, L | 1 |
| Anand, SS; Eikelboom, JW; Hankey, GJ; Tran, HA | 1 |
| Yadav, J | 1 |
| Bhatt, DL; Meadows, TA | 1 |
| Freedman, JE | 1 |
| Durackova, Z; Muchova, J; Nocun, M; Ulicna, O; Watala, C | 1 |
| Biczysko, W; Elikowski, W; Hanszke, E; Kruk-Zagajewska, A; Rzeźniczak, J; Zawilska, K | 1 |
| Gu, Y; Lewis, DF; Wang, Y; Zhao, S | 1 |
| Ebel, R; Hohlfeld, T; Höltje, HD; Jessen, G; Schrör, K; Weber, AA; Weber, H; Zimmermann, N | 1 |
| Banach, M; Boncler, M; Czyz, M; Dolnik, M; Gresner, P; Markuszewski, L; Nocun, M; Rysz, J; Rywaniak, J; Watala, C; Wilk, R | 1 |
| Gams, E; Hohlfeld, T; Kurt, M; Weber, AA; Wenzel, F; Winter, J; Zimmermann, N | 1 |
| Bednar, F; Hlavicka, J; Jedlickova, V; Osmancik, P; Paluch, Z; Vanek, T | 1 |
| Badimon, L; Vilahur, G | 1 |
| Davì, G; De Cristofaro, R; Dragani, A; Falco, A; Fioritoni, F; Lattanzio, S; Lessiani, G; Mattoscio, D; Recchiuti, A; Rocca, B; Romano, M; Santilli, F | 1 |
| Bhatt, DL; Easton, JD; Eikelboom, JW; Fox, KA; Hamm, C; Hankey, GJ; Hu, T; Johnston, SC; Mak, KH; Montalescot, G; Steg, PG; Steinhubl, SR; Thom, J; Topol, EJ | 1 |
| Del Soldato, P; Erdman, K; Erdmann, K; Giustarini, D; Perrino, E; Rossi, R; Rossoni, G; Schröder, H; Sparatore, A; Tazzari, V | 1 |
| Lanas, A; Nardulli, G | 1 |
| Daví, G; Grove, EL; Hedegaard, SS; Hvas, AM; Kristensen, SD; Refsgaard, J; Rocca, B | 1 |
| Cattaneo, M | 1 |
| Lindhoff-Last, E; Mani, H | 1 |
| Ciabattoni, G; Davì, G; Dragani, A; Ferrante, E; Habib, A; Lattanzio, S; Mattoscio, D; Mucci, L; Pascale, S; Patrono, C; Petrucci, G; Ranelletti, FO; Recchiuti, A; Rocca, B | 1 |
| Alamanni, F; Anselmo, A; Brambilla, M; Camera, M; Centenaro, C; Colli, S; Eligini, S; Parolari, A; Tremoli, E | 1 |
| Basili, S; Cavoni, A; Ciabattoni, G; Davì, G; De Feudis, L; Guizzardi, G; Lattanzio, S; Meneguzzi, A; Minuz, P; Paloscia, L; Patrono, C; Pettinella, C; Santilli, F; Traisci, G | 1 |
| Grove, EL; Hedegaard, SS; Hvas, AM; Johnsen, HL; Kristensen, SD; Mortensen, J; Pedersen, SB | 1 |
| Conroy, RM; Cox, D; Foley, D; Kenny, D; McCall, M; Peace, A; Tedesco, T | 1 |
| Bounameaux, H; Cairols, MA; Clement, DL; Coccheri, S; Fiessinger, JN; Fletcher, JP; Hoffmann, U; Turpie, AG | 1 |
| Böhm, A; Daum, G; Geisslinger, G; Hohlfeld, T; Nüsing, RM; Polzin, A; Rauch, BH; Schrör, K; Ulrych, T | 1 |
| Akesson, A; Bremme, K; Hjemdahl, P; Perneby, C; Vahter, M | 1 |
| Baumgärtel-Allekotte, D; Fischer, J; Heim, Kh; Kaber, G; Kaiser, B; Nagy, N; Nossmann, S; Rauch, B; Schrör, K; Weber, A | 1 |
| Di Minno, G | 1 |
| Dhanji, AR; Kirkby, NS; Leadbeater, PD; Milne, GL; Mitchell, JA; Thomas, S; Tucker, AT; Warner, TD | 1 |
| Capone, M; Di Febbo, C; Evangelista, V; Fava, C; Gleim, S; Hwa, J; Levantesi, G; Martin, K; Minuz, P; Patrignani, P; Porreca, E; Rade, J; Stitham, J; Tacconelli, S; Tang, WH; Wen, L | 1 |
| Angelico, F; Basili, S; Cangemi, R; Carnevale, R; Lauro, D; Nigro, C; Pignatelli, P; Proietti, M; Violi, F | 1 |
| Caudrillier, A; Gilliss, BM; Kessenbrock, K; Looney, MR; Marques, MB; Monestier, M; Nguyen, JX; Toy, P; Werb, Z | 1 |
| Ducrocq, X; Fay, R; Lacour, JC; Lecompte, T; Richard, S; Toussaint-Hacquard, M | 1 |
| Anfossi, G; Barale, C; Cavalot, F; Doronzo, G; Mattiello, L; Pagliarino, A; Russo, I; Trovati, M; Viretto, M | 1 |
| Aberg, JA; Berger, JS; Bhardwaj, N; Cavanagh, K; Gettenberg, G; Hu, L; Merolla, M; Montenont, E; Nardi, MA; O'Brien, M; Valdes, V | 1 |
| Sas, K; Sztriha, LK; Vadász, D; Vécsei, L | 1 |
| Chelikani, P; Douville, K; Gleim, S; Hwa, J; Li, H; Martin, KA; Rade, JJ; Stitham, J; Tang, WH | 1 |
| Hohlfeld, T; Kelm, M; Polzin, A; Schrör, K; Zeus, T | 1 |
| Jackson, EC; McNicol, A; Ortar, G | 1 |
| Berger, JS; Boone, JL; Jefferies, JL; Jesse, RL; Maisel, AS; McConnell, JP; McCullough, PA; Neath, SX; Wu, AH | 1 |
| Alves, MT; Borges, KB; Bosco, AA; Campos, FM; Carvalho, MG; Duarte, RC; Dusse, LM; Faria, MC; Fernandes, AP; Filho, OA; Gonçalves, GS; Gonçalves, LH; Sandrim, VC | 1 |
| Borovitov, ME; Chepanov, SV; Petrishchev, NN; Sel'kov, SA; Seliutin, AV; Vasina, LV; Veselkina, OC | 1 |
| Frank, S; Guleserian, K; Heistein, L; Journeycake, J; Lemler, M; Mir, A; Wolovitis, J | 1 |
| Armstrong, PC; Chan, MV; Finsterbusch, M; Hoefer, T; Kirkby, NS; Warner, TD | 1 |
| Dannenberg, L; Hohlfeld, T; Kelm, M; Levkau, B; Polzin, A; Sansone, R; Zeus, T | 1 |
| Amadio, P; Barbieri, SS; Cavalca, V; Porro, B; Sandrini, L; Squellerio, I; Tarantino, E; Tremoli, E; Turnu, L | 1 |
| Bottsford-Miller, JN; Dial, EJ; Dorniak, PL; Fang, D; Filant, J; Haemmerle, M; Hansen, JM; Hatakeyama, H; Hu, W; Huang, Y; Lichtenberger, LM; Lyons, Y; Pradeep, S; Previs, RA; Shen, F; Sood, AK; Taylor, M; Wagner, MJ | 1 |
| Cortina, B; Latorre, A; Moscardó, A; Santos, MT; Vallés, J | 1 |
| Bartkowski, K; Dannenberg, L; Hohlfeld, T; Kelm, M; Levkau, B; Mohring, A; Piayda, K; Polzin, A; Schneider, T; Zako, S; Zeus, T | 1 |
| Bliden, KP; Centofanti, R; Gurbel, PA; Jarvis, S; Tantry, US; Troullos, E; Venkataraman, P; Zhu, J | 1 |
| Andrews, KL; Chin-Dusting, JPF; Dragoljevic, D; Gaspari, T; Jefferis, AM; Jennings, GL; Khan, SI; Lee, MKS; Moore, XL; Murphy, AJ; Shihata, WA; Vinh, A | 1 |
| Byrne, BM; Khalid, A | 1 |
| Assis, J; Ferreira, M; Freitas-Silva, M; Medeiros, R; Nunes, JP; Pinto, R | 1 |
| Ahmetaj-Shala, B; Armstrong, PC; Crescente, M; Ferreira, P; Kirkby, NS; Lopes Pires, ME; Mitchell, JA; Vaja, R; Warner, TD | 1 |
| Ahlbrecht, S; Benkhoff, M; Dannenberg, L; Helten, C; Huhn-Wientgen, R; Kelm, M; Levkau, B; M'Pembele, R; Mourikis, P; Petzold, T; Polzin, A; Richter, H; Thienel, M; Zako, S; Zikeli, D | 1 |
| Abdelazeem, H; Aljesri, K; Norel, X; Ozen, G; Topal, G; Turkyılmaz, G; Turkyılmaz, S | 1 |
| Beggiato, E; Bertozzi, I; Betti, S; Bucelli, C; Carli, G; Cattaneo, D; Cavalca, V; De Stefano, V; Di Ianni, M; Dragani, A; Elli, EM; Iurlo, A; Lanzarone, G; Loscocco, GG; Palandri, F; Patrono, C; Petrucci, G; Porro, B; Priolo, S; Ranalli, P; Randi, ML; Ricco, A; Rocca, B; Rodeghiero, F; Rossi, E; Ruggeri, M; Soldati, D; Specchia, G; Timillero, A; Tosetto, A; Vannucchi, AM; Vianelli, N | 1 |
| Patrono, C; Rocca, B | 1 |
| Barrs, VR; Griebsch, C; Hall, E | 1 |
| Cheung, SS; Hellsten, Y; Lundberg Slingsby, MH; Nørregaard, LB; Wickham, KA | 1 |
| Al Dulaimi, M; Strauss, JF; Walsh, SW | 1 |
| Schrör, K; Trenk, D; Verheugt, FWA | 1 |
| Boyce, JA; Buchheit, KM; Cahill, KN; Chen, CC; Cho, L; Cui, J; Feng, C; Hacker, J; Israel, E; Laidlaw, TM; Le, M | 1 |
| Patrono, C | 1 |
| Karwatowska-Prokopczuk, E; Li, L; Tsimikas, S; Witztum, JL; Yang, J | 1 |
| Ainsworth, NL; Armstrong, AC; Bradbury, J; Cafferty, FH; Cameron, DA; Capaldi, LM; Churn, M; Cleary, S; Cunningham, D; Dawson, LK; Eaton, JD; Eichholz, A; Gentry-Maharaj, A; Gilbert, DC; Hatem, D; Herbertson, RA; Horan, G; Hubner, RA; Joharatnam-Hogan, N; Kagzi, MM; Khoo, V; Kunene, VL; Kynaston, HG; Langley, RE; Lofts, FJ; MacKenzie, M; Meade, A; Mullen, R; Narahari, K; O'Callaghan, A; Patrono, C; Patterson, DM; Petrucci, G; Ring, A; Rizvi, AJ; Robbins, A; Rocca, B; Scott-Brown, MWG; Sothi, S; Srihari, N; Stokes, Z; Swinson, DEB; Walker, GA; Walther, A; Wheatley, DA; Wilson, RH | 1 |
50 review(s) available for aspirin and thromboxanes
| Article | Year |
|---|---|
The role of prostaglandins in platelet function.
Topics: Acetylation; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Blood Platelets; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Epoprostenol; Hemostasis; Humans; Peroxides; Phospholipases; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxane A2; Thromboxanes | 1979 |
New directions in prostaglandin research and their possible implications for immunologic and nonimmunologic inflammation.
Topics: Arachidonic Acids; Aspirin; Cyclic AMP; Drug Hypersensitivity; Humans; Lipoxygenase; Prostaglandins; Prostaglandins E; SRS-A; Thromboxanes | 1977 |
The role of prostaglandins in platelet function.
Topics: Animals; Arteriosclerosis; Aspirin; Bleeding Time; Blood Platelets; Chemical Phenomena; Chemistry; Cyclic AMP; Epoprostenol; Haplorhini; Humans; Male; Platelet Aggregation; Prostaglandins; Thromboxane A2; Thromboxane B2; Thromboxanes | 1979 |
The multiple pathways of arachidonic acid metabolism.
Topics: Animals; Arachidonic Acids; Arteries; Aspirin; Blood Platelets; Humans; Peroxides; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins; Thromboxanes; Vasoconstriction | 1978 |
Unstable metabolites of arachidonic acid and their role in haemostasis and thrombosis.
Topics: Arachidonic Acids; Aspirin; Epoprostenol; Hemostasis; Humans; Peroxides; Platelet Adhesiveness; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins; Thrombosis; Thromboxanes; Vasodilator Agents | 1978 |
Steroids, aspirin, and inflammation.
Topics: Animals; Aspirin; Cell Membrane; Chemotaxis; Cytoplasmic Granules; Glucocorticoids; Humans; Infections; Inflammation; Opsonin Proteins; Phagocytes; Phagocytosis; Prostaglandins; Thromboxanes | 1977 |
Platelet-endothelial cell interactions.
Topics: Animals; Arteriosclerosis; Aspirin; Blood Platelets; Blood Vessels; Complement System Proteins; Endothelium; Epoprostenol; Factor VIII; Granulocytes; Hemostasis; Humans; Platelet Adhesiveness; Platelet Aggregation; Thrombin; Thrombosis; Thromboxanes | 1979 |
Prostaglandins in circulatory disorders.
Topics: Angiotensin II; Antihypertensive Agents; Arachidonic Acids; Arteriosclerosis; Aspirin; Blood Platelets; Diet; Dipyridamole; Eicosanoic Acids; Humans; Hypertension; Platelet Aggregation; Prostaglandins; Thrombosis; Thromboxanes; Vascular Diseases | 1979 |
Inhibitors of prostaglandin, prostacyclin, and thromboxane synthesis.
Topics: Animals; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Epoprostenol; Female; Humans; Indomethacin; Muscle Contraction; Prostaglandins; Thromboxane-A Synthase; Thromboxanes; Uterus | 1978 |
Thromboxane synthase inhibitors and receptor antagonists.
Topics: Aspirin; Humans; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane-A Synthase; Thromboxanes | 1992 |
An aspirin a day to prevent prematurity.
Topics: Aspirin; Birth Weight; Female; Fetal Growth Retardation; Health Status Indicators; Humans; Obstetric Labor, Premature; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Pregnancy, Multiple; Prostaglandins; Randomized Controlled Trials as Topic; Risk Factors; Thromboxanes | 1992 |
[Acetylsalicylic acid and pregnancy hypertension].
Topics: Aspirin; Epoprostenol; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Randomized Controlled Trials as Topic; Thromboxanes | 1991 |
Physiology of low-dose aspirin therapy for the prevention of preeclampsia.
Topics: Aspirin; Female; Fetus; Humans; Pre-Eclampsia; Pregnancy; Prostaglandins; Thromboxanes | 1990 |
Pathological significance of the thromboxane-prostacyclin hypothesis.
Topics: Animals; Arteriosclerosis; Aspirin; Blood Platelets; Blood Vessels; Epoprostenol; Humans; Prostaglandins, Synthetic; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes; Vascular Diseases | 1985 |
Low-dose aspirin: treatment for the imbalance of increased thromboxane and decreased prostacyclin in preeclampsia.
Topics: Aspirin; Clinical Trials as Topic; Epoprostenol; Female; Humans; Maternal-Fetal Exchange; Pre-Eclampsia; Pregnancy; Thromboxanes | 1989 |
Platelets and antiplatelet therapy in ischemic heart disease.
Topics: Angina Pectoris; Angioplasty, Balloon; Arteriosclerosis; Aspirin; Blood Platelets; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease; Cyclooxygenase Inhibitors; Dipyridamole; Epoprostenol; Humans; Myocardial Infarction; Platelet Adhesiveness; Sulfinpyrazone; Thromboxanes | 1986 |
Prostaglandins and other metabolites of arachidonic acid. An overview for the otolaryngologist.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Humans; Hypersensitivity; Indomethacin; Inflammation; Leukotriene A4; Lipoxygenase; Neoplasms; Phospholipases; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxanes | 1985 |
The role of eicosanoids in respiratory mucus hypersecretion.
Topics: Animals; Arachidonic Acids; Aspirin; Asthma; Bronchial Diseases; Cells, Cultured; Fatty Acids, Unsaturated; Humans; Leukotriene B4; Leukotrienes; Mucoproteins; Mucus; Prostaglandins; Thromboxanes | 1985 |
[Hypercoagulability and cerebral infarction].
Topics: Aspirin; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Cerebral Infarction; Clinical Trials as Topic; Dipyridamole; Glycoproteins; Humans; Platelet Aggregation; Sulfinpyrazone; Suloctidil; Thromboxanes; von Willebrand Factor | 1986 |
[Analogs of prostaglandin-related substances and inhibitors of their synthesis and metabolism. Clinical application: cardiovascular diseases].
Topics: Angina Pectoris; Aspirin; Coronary Disease; Epoprostenol; Humans; Hypertension; Methacrylates; Myocardial Infarction; Oxidoreductases; Platelet Aggregation; Thromboxane-A Synthase; Thromboxanes; Urokinase-Type Plasminogen Activator | 1985 |
Inhibition of platelet function in thrombosis.
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Chromatography, Gas; Depression, Chemical; Eicosanoic Acids; Female; Humans; Male; Microcirculation; Neutrophils; Thrombosis; Thromboxanes; Tritium | 1985 |
[Prostaglandins and related substances: regulation of arachidonic acid metabolism by drugs].
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Butylated Hydroxytoluene; Cyclooxygenase Inhibitors; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Phospholipases A; Prostaglandins; Rats; SRS-A; Thromboxanes | 1985 |
Prostacyclin: its biosynthesis, actions and clinical potential.
Topics: Angiotensin I; Animals; Arteries; Aspirin; Blood Platelets; Bradykinin; Cyclic AMP; Epoprostenol; Hemostasis; Humans; Muscle, Smooth, Vascular; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins; Thromboxanes | 1981 |
Cyclic nucleotides in hemostasis and thrombosis.
Topics: Aspirin; Blood Platelets; Calcium; Cyclic AMP; Cyclic GMP; Diet; Hemostasis; Humans; Male; Phosphorylation; Platelet Aggregation; Prostaglandins; Protein Kinases; Proteins; Thrombosis; Thromboxanes | 1980 |
Studies on the biological balance between thromboxanes and prostacyclins in relation to the platelet-vessel wall interaction.
Topics: Adolescent; Adult; Aged; Aspirin; Bleeding Time; Blood Platelets; Blood Vessels; Child; Diabetes Mellitus; Eicosapentaenoic Acid; Epoprostenol; Fatty Acids, Unsaturated; Humans; Hydrocortisone; Male; Middle Aged; Phosphodiesterase Inhibitors; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins; Thromboxanes | 1982 |
Prostaglandins and anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Central Nervous System Diseases; Cyclic AMP; Drug Hypersensitivity; Female; Gastrointestinal Diseases; Glucocorticoids; Hemostasis; Humans; Kidney; Leukotriene B4; Liver; Mice; Nutrition Disorders; Pregnancy; Prostaglandins; Puerperal Disorders; Thrombosis; Thromboxanes | 1983 |
Mechanisms of action: aspirin.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Endothelium; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Salicylates; Salicylic Acid; Thromboxanes | 1983 |
Prostaglandins, platelets, and atherosclerosis.
Topics: Animals; Arachidonic Acids; Arteriosclerosis; Aspirin; Blood Circulation; Blood Vessels; Carotid Artery Thrombosis; Cyclooxygenase Inhibitors; Dogs; Epoprostenol; Female; Humans; Infusions, Parenteral; Male; Mice; Myocardial Infarction; Platelet Aggregation; Prostaglandins; Rabbits; Rats; Structure-Activity Relationship; Thromboembolism; Thromboxane A2; Thromboxanes | 1980 |
Prostaglandins, slow-reacting substances (leukotrienes) and the lung.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Bronchi; Epoprostenol; Guinea Pigs; Humans; Indomethacin; Infant, Newborn; Lung; Lung Diseases, Obstructive; Prostaglandin-Endoperoxide Synthases; Prostaglandins; SRS-A; Thromboxanes | 1981 |
Thromboxane A2, prostacyclin and aspirin: effects on vascular tone and platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Vessels; Cats; Coronary Vessels; Epoprostenol; Guinea Pigs; Humans; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins; Prostaglandins E; Prostaglandins F; Rabbits; Thromboxane A2; Thromboxanes | 1980 |
The role of prostacyclin and thromboxane A2 in the regulation of platelet behaviour.
Topics: Aspirin; Dipyridamole; Epoprostenol; Hemorrhage; Humans; Platelet Aggregation; Prostaglandins; Thrombosis; Thromboxane A2; Thromboxanes | 1980 |
Biosynthesis of prostaglandins and thromboxanes in lung.
Topics: Animals; Arachidonic Acids; Aspirin; Depression, Chemical; Guinea Pigs; Histocytochemistry; Humans; In Vitro Techniques; Lung; Prostaglandins; Rabbits; Rats; Thromboxanes; Tissue Distribution | 1981 |
[Platelets and prostaglandins in ischemic cardiopathy. Theoretical and practical aspects and research prospects].
Topics: Arteriosclerosis; Aspirin; Blood Platelets; Coronary Disease; Dipyridamole; Humans; Platelet Aggregation; Platelet Count; Prostaglandins; Sulfinpyrazone; Thromboxanes | 1982 |
Antiplatelet drugs. A comparative review.
Topics: Adenosine Diphosphate; Animals; Aspirin; Base Sequence; Blood Platelets; Consensus Sequence; Humans; Molecular Sequence Data; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Thrombin; Thrombosis; Thromboxanes | 1995 |
The case of low-dose aspirin for the prevention of myocardial infarction: but how low is low?
Topics: Aspirin; Coronary Disease; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Epoprostenol; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Thromboxanes | 1997 |
Genetic and pharmacological analysis of prostanoid receptor function.
Topics: Animals; Aspirin; Biological Transport; Bone Resorption; Cell Nucleus; Colonic Neoplasms; Cyclooxygenase Inhibitors; Drug Design; Female; Fever; GTP-Binding Proteins; Humans; Hypersensitivity; Inflammation; Ischemia; Mice; Mice, Knockout; Neovascularization, Pathologic; Pain; Placenta; Pregnancy; Prostaglandin Antagonists; Prostaglandins; Protein Structure, Tertiary; Receptors, Prostaglandin; Receptors, Thromboxane; Signal Transduction; Thromboxanes; Vasodilation | 2001 |
[Platelet inhibitors: old and new].
Topics: Abciximab; Antibodies, Monoclonal; Arteriosclerosis; Aspirin; Clopidogrel; Coronary Disease; Dipyridamole; Drug Monitoring; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Membrane Proteins; Patient Selection; Peptides; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thrombosis; Thromboxanes; Ticlopidine | 2002 |
Selective COX-2 inhibition and cardiovascular effects: a review of the rofecoxib development program.
Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Blood Pressure; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Interactions; Drug Therapy, Combination; Endothelium, Vascular; Epoprostenol; Humans; Isoenzymes; Lactones; Membrane Proteins; Models, Animal; Naproxen; Osteoarthritis; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Randomized Controlled Trials as Topic; Sulfones; Thrombosis; Thromboxanes | 2003 |
Aspirin insensitive eicosanoid biosynthesis in cardiovascular disease.
Topics: Angina, Unstable; Aspirin; Cardiovascular Diseases; Drug Resistance; Eicosanoids; Humans; Isoprostanes; Leukotrienes; Muscle, Smooth, Vascular; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Thromboxanes | 2003 |
Eicosanoids in preeclampsia.
Topics: Antioxidants; Aspirin; Eicosanoids; Epoprostenol; Female; Humans; Lipid Peroxidation; Oxidative Stress; Pre-Eclampsia; Pregnancy; Thromboxanes | 2004 |
Aspirin and coronary artery disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Blood Platelets; Clinical Trials as Topic; Coronary Artery Disease; Cyclooxygenase Inhibitors; Drug Resistance; Female; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Models, Biological; Platelet Aggregation; Prostaglandins; Risk Factors; Thrombosis; Thromboxanes | 2004 |
Aspirin resistance.
Topics: Aspirin; Cardiovascular Diseases; Dose-Response Relationship, Drug; Drug Resistance; Forecasting; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Thromboxanes | 2007 |
Clinical aspects of platelet inhibitors and thrombus formation.
Topics: Aspirin; Atherosclerosis; Blood Platelets; Cardiovascular Diseases; Cilostazol; Clopidogrel; Dipyridamole; Drug Resistance; Humans; Pentanoic Acids; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Purinergic P2 Receptor Antagonists; Pyridines; Receptor, PAR-1; Stents; Tetrazoles; Thrombosis; Thromboxanes; Ticlopidine | 2007 |
Coronary atherothrombotic disease: progress in antiplatelet therapy.
Topics: Aspirin; Blood Platelets; Coronary Artery Disease; Coronary Thrombosis; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Thromboxanes | 2008 |
[Risk of gastrointestinal bleeding with aspirin and platelet antiaggregants].
Topics: Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aspirin; Clopidogrel; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Histamine H2 Antagonists; Humans; Middle Aged; Misoprostol; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk Factors; Thromboxanes; Ticlopidine | 2009 |
[Diagnosis, causes, relevance of a complex phenomenon. Resistance to aspirin and clopidogrel].
Topics: Aspirin; Blood Platelets; Clopidogrel; Drug Interactions; Drug Resistance; Humans; Phosphorylation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thrombosis; Thromboxanes; Ticlopidine | 2009 |
Aspirin and clopidogrel resistance: possible mechanisms and clinical relevance. Part II: Potential causes and laboratory tests.
Topics: Age Factors; Aspirin; Biological Availability; Clopidogrel; Drug Administration Schedule; Drug Interactions; Drug Resistance; Humans; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Polymorphism, Genetic; Sex Factors; Signal Transduction; Thromboxanes; Ticlopidine | 2013 |
The current and future landscape of urinary thromboxane testing to evaluate atherothrombotic risk.
Topics: Aspirin; Biomarkers; Blood Platelets; Drug Resistance; Fibrinolytic Agents; Humans; Patient Selection; Platelet Function Tests; Precision Medicine; Predictive Value of Tests; Risk Assessment; Risk Factors; Thrombosis; Thromboxanes; Treatment Outcome; Urinalysis | 2014 |
Cyclooxygenases and the cardiovascular system.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Cardiovascular Physiological Phenomena; Cardiovascular System; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Stability; Endothelial Cells; Humans; Hydrogen-Ion Concentration; Kidney; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Temperature; Thromboxanes; Thymus Gland | 2021 |
Cyclooxygenase Inhibitors and Cancer: The Missing Pieces.
Topics: Aspirin; Carcinogenesis; Colorectal Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Gastrointestinal Neoplasms; Humans; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Thromboxanes | 2023 |
60 trial(s) available for aspirin and thromboxanes
| Article | Year |
|---|---|
[Modification of thrombocyte function in diagnostic and therapeutic interventions in cardiology].
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Fibrinolysis; Follow-Up Studies; Humans; Molsidomine; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Recurrence; Thromboxanes; Tissue Plasminogen Activator | 1991 |
[Pharmacological correction by roxicam of the prostacyclin-thromboxane system in acute myocardial infarction complicated by heart failure].
Topics: 6-Ketoprostaglandin F1 alpha; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiac Glycosides; Diuretics; Epoprostenol; Heart Failure; Humans; Myocardial Infarction; Nitrates; Piroxicam; Thromboxane A2; Thromboxane B2; Thromboxanes | 1991 |
Multi-Hospital Eastern Atlantic Restenosis Trial. II: A placebo-controlled trial of thromboxane blockade in the prevention of restenosis following coronary angioplasty.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Angiography; Coronary Disease; Double-Blind Method; Follow-Up Studies; Humans; Mid-Atlantic Region; Placebos; Platelet Aggregation Inhibitors; Prospective Studies; Receptors, Prostaglandin; Receptors, Thromboxane; Recurrence; Sulfonamides; Thromboxanes | 1991 |
Doppler ultrasound and aspirin in recognition and prevention of pregnancy-induced hypertension.
Topics: Administration, Oral; Adult; Aspirin; Blood Platelets; Drug Administration Schedule; Drug Evaluation; Epoprostenol; Female; Humans; Hypertension; Infant, Low Birth Weight; Infant, Newborn; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Second; Proteinuria; Randomized Controlled Trials as Topic; Risk Factors; Tablets; Thromboxanes; Ultrasonography | 1990 |
Long-term maintenance of thromboxane inhibition by two different aspirin regimens in patients with unstable angina.
Topics: Angina, Unstable; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Thromboxane B2; Thromboxanes | 1990 |
Effects of non-steroidal anti-inflammatory drugs on prostacyclin and thromboxane biosynthesis in patients with mild essential hypertension.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Chromatography, Affinity; Epoprostenol; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypertension; Ibuprofen; Kidney; Male; Middle Aged; Sulindac; Thromboxanes | 1990 |
Differential effect of aspirin on thromboxane and prostaglandin biosynthesis in man.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Humans; Infusions, Intravenous; Injections; Male; Prostaglandins; Thromboxane B2; Thromboxanes | 1989 |
Low-dose aspirin: treatment for the imbalance of increased thromboxane and decreased prostacyclin in preeclampsia.
Topics: Aspirin; Clinical Trials as Topic; Epoprostenol; Female; Humans; Maternal-Fetal Exchange; Pre-Eclampsia; Pregnancy; Thromboxanes | 1989 |
Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Epoprostenol; Female; Fetus; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Random Allocation; Thromboxane A2; Thromboxane B2; Thromboxanes | 1989 |
Comparison of the effect of aspirin and choline magnesium trisalicylate on thromboxane biosynthesis in human platelets: role of the acetyl moiety.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Blood Platelets; Choline; Double-Blind Method; Female; Humans; Male; Random Allocation; Salicylates; Thromboxane B2; Thromboxanes | 1989 |
Platelets and antiplatelet therapy in ischemic heart disease.
Topics: Angina Pectoris; Angioplasty, Balloon; Arteriosclerosis; Aspirin; Blood Platelets; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease; Cyclooxygenase Inhibitors; Dipyridamole; Epoprostenol; Humans; Myocardial Infarction; Platelet Adhesiveness; Sulfinpyrazone; Thromboxanes | 1986 |
Thromboxane receptor blockade versus cyclooxigenase inhibition: antiplatelet effects in patients.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angioplasty, Balloon; Arteriosclerosis; Aspirin; Bleeding Time; Blood Platelets; Clinical Trials as Topic; Collagen; Cyclooxygenase Inhibitors; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane B2; Thromboxanes | 1986 |
[Hypercoagulability and cerebral infarction].
Topics: Aspirin; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Cerebral Infarction; Clinical Trials as Topic; Dipyridamole; Glycoproteins; Humans; Platelet Aggregation; Sulfinpyrazone; Suloctidil; Thromboxanes; von Willebrand Factor | 1986 |
A comparison of the effects of a thromboxane antagonist and cyclo-oxygenase inhibitor on platelet accumulation in arterial grafts.
Topics: Aorta; Aspirin; Biphenyl Compounds; Blood Platelets; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Dipyridamole; Femoral Artery; Humans; Thrombosis; Thromboxanes; Vascular Surgical Procedures | 1987 |
Low- vs high-dose aspirin. Effects on platelet function in hyperlipoproteinemic and normal subjects.
Topics: Adult; Aspirin; Bleeding Time; Blood Platelets; Epoprostenol; Female; Humans; Hyperlipoproteinemia Type II; Lipids; Male; Middle Aged; Platelet Aggregation; Platelet Factor 4; Thromboxanes | 1986 |
A critical appraisal of the clinical efficiency of anti-platelet drugs.
Topics: Angina Pectoris; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Dipyridamole; Double-Blind Method; Hemorrhage; Humans; Myocardial Revascularization; Prospective Studies; Sulfinpyrazone; Thromboxanes | 1986 |
Effects of low doses of aspirin, 10 mg and 30 mg daily, on bleeding time, thromboxane production and 6-keto-PGF1 alpha excretion in healthy subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Bleeding Time; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Function Tests; Thromboxane A2; Thromboxane B2; Thromboxanes; Time Factors | 1987 |
[Therapeutic prospects and prostaglandins in vascular pathology].
Topics: Angina Pectoris; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Arteritis; Aspirin; Blood Platelets; Cardiovascular Diseases; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Epoprostenol; Female; Humans; Male; Myocardial Infarction; Prostaglandins; Raynaud Disease; Thromboxanes | 1985 |
Differential inhibition by low-dose aspirin of human venous prostacyclin synthesis and platelet thromboxane synthesis.
Topics: Aspirin; Blood Platelets; Depression, Chemical; Epoprostenol; Humans; Platelet Aggregation; Prostaglandins; Thromboxane A2; Thromboxanes; Veins | 1981 |
Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA).
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Triphosphatases; Aged; Aorta, Abdominal; Aortic Aneurysm; Aspirin; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Cardiac Output; Female; Humans; Intraoperative Care; Male; Middle Aged; Myocardial Contraction; Myocardium; Papillary Muscles; Premedication; Pulmonary Wedge Pressure; Thromboxane B2; Thromboxanes | 1981 |
Improved aortocoronary bypass patency by low-dose aspirin (100 mg daily). Effects on platelet aggregation and thromboxane formation.
Topics: Aspirin; Blood Platelets; Clinical Trials as Topic; Coronary Artery Bypass; Double-Blind Method; Female; Graft Survival; Humans; Male; Middle Aged; Platelet Aggregation; Prospective Studies; Random Allocation; Thromboxanes | 1984 |
Prostaglandins and endometriosis.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Clinical Trials as Topic; Endometriosis; Epoprostenol; Female; Humans; In Vitro Techniques; Indomethacin; ortho-Aminobenzoates; Prostaglandin Antagonists; Prostaglandins; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
Prostacyclin and thromboxane in ovarian cancer: effect of cytostatics and prostaglandin synthesis inhibitors.
Topics: 6-Ketoprostaglandin F1 alpha; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Epoprostenol; Female; Humans; Indomethacin; Ovarian Neoplasms; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
Reduced side effects by low dose of acetylsalicylic acid (ASA) in patients with myocardial infarction; estimations of serum thromboxane B2 and PGF2 alpha.
Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Dinoprost; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Prostaglandins F; Thromboxane B2; Thromboxanes | 1984 |
Effect of acetylsalicylic acid on plasma thromboxane B2 and platelet aggregation in man.
Topics: Adult; Aspirin; Dose-Response Relationship, Drug; Humans; Male; Platelet Aggregation; Thromboembolism; Thromboxane B2; Thromboxanes | 1983 |
Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials.
Topics: Adult; Angina Pectoris; Angina Pectoris, Variant; Arteries; Aspirin; Clinical Trials as Topic; Coronary Circulation; Coronary Vessels; Double-Blind Method; Female; Humans; Indomethacin; Ischemia; Male; Middle Aged; Recurrence; Thromboxane A2; Thromboxane B2; Thromboxanes; Time Factors; Veins | 1981 |
Effect of various doses of acetylsalicylic acid in combination with dipyridamole on the balance between prostacyclin and thromboxane in human serum.
Topics: Adult; Aspirin; Dipyridamole; Epoprostenol; Female; Humans; Middle Aged; Prostaglandins; Prostaglandins F, Synthetic; Thromboxanes; Time Factors | 1981 |
Prostacyclin, thromboxane and prostaglandin F2 alpha in suction blister fluid of human skin: effect of systemic aspirin and local glucocorticosteroid treatment.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Betamethasone; Blister; Clobetasol; Dinoprost; Epoprostenol; Exudates and Transudates; Humans; Male; Prostaglandins; Prostaglandins F; Skin; Thromboxane A2; Thromboxane B2; Thromboxanes | 1981 |
Anti platelet agents for strokes and myocardial infarction: a critical appraisal of recent clinical trials.
Topics: Aspirin; Cerebrovascular Disorders; Clinical Trials as Topic; Collagen; Coronary Disease; Dipyridamole; Evaluation Studies as Topic; Humans; Myocardial Infarction; Platelet Aggregation; Prostaglandins; Recurrence; Sulfinpyrazone; Thromboxanes | 1981 |
Eicosanoid biosynthesis in patients with stable angina: beneficial effects of very low dose aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Analysis of Variance; Angina Pectoris; Aspirin; Cardiac Pacing, Artificial; Dose-Response Relationship, Drug; Humans; Lactates; Middle Aged; Physical Exertion; Thromboxanes | 1994 |
Effect of low-dose aspirin on thromboxane production and the antihypertensive effect of captopril.
Topics: Adult; Aspirin; Blood Platelets; Blood Pressure; Captopril; Double-Blind Method; Drug Interactions; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Thromboxane B2; Thromboxanes | 1993 |
Production of prostacyclin and thromboxane in lupus pregnancies: effect of small dose of aspirin.
Topics: Adult; Antibodies, Antiphospholipid; Aspirin; Chromatography, High Pressure Liquid; Epoprostenol; Female; Humans; Lupus Erythematosus, Systemic; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Radioimmunoassay; Thromboxanes | 1993 |
Anti-platelet effects of 100 mg alternate day oral aspirin: a randomized, double-blind, placebo-controlled trial of regular and enteric coated formulations in men and women.
Topics: Adenosine Diphosphate; Administration, Oral; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cardiovascular Diseases; Double-Blind Method; Drug Administration Schedule; Epinephrine; Epoprostenol; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Radioimmunoassay; Risk Factors; Thromboxanes | 1996 |
Effect of sucralfate on aspirin induced mucosal injury and impaired haemostasis in humans.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Biopsy; Cross-Over Studies; Dinoprostone; Double-Blind Method; Gastric Mucosa; Gastrointestinal Hemorrhage; Hemostasis; Humans; Sucralfate; Thromboxanes | 1997 |
Thromboxane production in human lung during cardiopulmonary bypass: beneficial effect of aspirin?
Topics: Aged; Aged, 80 and over; Aspirin; Cardiopulmonary Bypass; Female; Humans; Lung; Male; Middle Aged; Thromboxane B2; Thromboxanes | 1998 |
Low-dose aspirin does not lower in vivo platelet activation in healthy smokers.
Topics: Adult; Aspirin; Blood Platelets; Cross-Over Studies; Double-Blind Method; Humans; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Prospective Studies; Smoking; Thromboxanes | 1998 |
Aprotinin counterbalances an increased risk of peri-operative hemorrhage in CABG patients pre-treated with Aspirin.
Topics: Aprotinin; Aspirin; Blood Loss, Surgical; Coronary Artery Bypass; Creatine Kinase; Double-Blind Method; Electrocardiography; Female; Fibrinolytic Agents; Hemostatics; Humans; Intraoperative Care; Isoenzymes; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Placebos; Postoperative Hemorrhage; Prospective Studies; Reproducibility of Results; Risk Factors; Thromboxanes | 1998 |
A randomized, placebo-controlled, crossover study of E5510 and aspirin in healthy volunteers.
Topics: Adult; Aspirin; Bleeding Time; Blood Platelets; Cross-Over Studies; Cyclic AMP; Double-Blind Method; Eicosanoids; Fatty Acids, Monounsaturated; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxanes | 1999 |
Effects of aspirin or picotamide, an antithromboxane agent, in combination with low-intensity oral anticoagulation in patients with acute myocardial infarction: a controlled randomized pilot trial.
Topics: Administration, Oral; Adult; Aged; Anticoagulants; Aspirin; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Phthalic Acids; Pilot Projects; Platelet Aggregation Inhibitors; Single-Blind Method; Thromboxanes | 1999 |
Specific inhibition of cyclooxygenase-2 with MK-0966 is associated with less gastroduodenal damage than either aspirin or ibuprofen.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Duodenal Ulcer; Enzyme Inhibitors; Female; Humans; Ibuprofen; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; Stomach Ulcer; Sulfones; Thromboxanes | 1999 |
Determinants of enhanced thromboxane biosynthesis in patients with systemic lupus erythematosus.
Topics: Adult; Antibodies, Antiphospholipid; Antigens; Aspirin; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Humans; Ischemia; Lupus Erythematosus, Systemic; Male; Middle Aged; Myocardial Infarction; Stroke; Thromboxane B2; Thromboxanes; Tissue Plasminogen Activator; Venous Thrombosis; von Willebrand Factor | 1999 |
A comparison of every-third-day versus daily low-dose aspirin therapy on serum thromboxane concentrations in healthy men and women.
Topics: Adolescent; Adult; Aspirin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Pilot Projects; Platelet Aggregation Inhibitors; Thromboxane B2; Thromboxanes; Time Factors | 2001 |
Incomplete thromboxane inhibition with 100 mg of intravenous acetylsalicylic acid in patients with acute ST elevation myocardial infarction: a placebo-controlled pilot trial.
Topics: Aged; Aspirin; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Humans; Injections, Intravenous; Male; Middle Aged; Myocardial Infarction; Pilot Projects; Streptokinase; Thromboxane A2; Thromboxane B2; Thromboxanes | 2001 |
High plasma concentrations of human urotensin II do not alter local or systemic hemodynamics in man.
Topics: Adult; Analysis of Variance; Aspirin; Blood Pressure; Carrier Proteins; Enzyme Inhibitors; Epoprostenol; Forearm; Hand; Humans; Infusions, Intra-Arterial; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Peptides; Pilot Projects; Plethysmography; Regional Blood Flow; Thromboxanes; Urotensins; Vasoconstrictor Agents; Veins | 2002 |
Aspirin dosage and thromboxane synthesis in patients with vascular disease.
Topics: Aged; Aspirin; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Aggregation Inhibitors; Thromboxane B2; Thromboxanes; Vascular Diseases | 2003 |
Effect of vitamins and aspirin on markers of platelet activation, oxidative stress and homocysteine in people at high risk of dementia.
Topics: Aged; Aged, 80 and over; Aspirin; Cognition Disorders; Dementia; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Isoprostanes; Male; Middle Aged; Oxidative Stress; Platelet Activation; Platelet Aggregation Inhibitors; Riboflavin; Thromboxanes; Vitamin B 12; Vitamins | 2003 |
Functional and biochemical evaluation of platelet aspirin resistance after coronary artery bypass surgery.
Topics: Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Coronary Artery Bypass; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Activation; Humans; Indomethacin; Isoenzymes; Membrane Proteins; P-Selectin; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Pyridines; Thromboxane-A Synthase; Thromboxanes; Time Factors | 2003 |
What is the lowest dose of aspirin for maximum suppression of in vivo thromboxane production after a transient ischemic attack or ischemic stroke?
Topics: Adult; Aged; Aspirin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Patient Compliance; Platelet Aggregation Inhibitors; Risk Factors; Stroke; Thromboxane B2; Thromboxanes; Treatment Outcome | 2004 |
In vivo aspirin supplementation inhibits nitric oxide consumption by human platelets.
Topics: Aspirin; Blood Platelets; Cyclic GMP; Dose-Response Relationship, Drug; Health; Humans; Isoenzymes; Nitric Oxide; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Thromboxanes; Time Factors | 2005 |
Aspirin-induced platelet inhibition in patients undergoing cardiac surgery.
Topics: Aortic Valve; Aspirin; Cardiopulmonary Bypass; Coronary Artery Bypass; Humans; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Thromboxanes | 2007 |
Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid: determinants and effect on cardiovascular risk.
Topics: Aged; Aspirin; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Follow-Up Studies; Humans; Internationality; Male; Middle Aged; Risk Factors; Survival Rate; Thromboxane B2; Thromboxanes | 2008 |
The contribution of cyclooxygenase-1 and -2 to persistent thromboxane biosynthesis in aspirin-treated essential thrombocythemia: implications for antiplatelet therapy.
Topics: Adult; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Etoricoxib; Female; Humans; Immunohistochemistry; Male; Middle Aged; Platelet Aggregation Inhibitors; Pyridines; Sulfones; Thrombocythemia, Essential; Thromboxane A2; Thromboxane B2; Thromboxanes; Treatment Outcome | 2010 |
Effect of two doses of aspirin on thromboxane biosynthesis and platelet function in patients undergoing coronary surgery.
Topics: Aged; Aspirin; Blood Platelets; Coronary Artery Bypass; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Thromboxanes; Treatment Outcome | 2010 |
Thromboxane Antagonism with terutroban in Peripheral Arterial Disease: the TAIPAD study.
Topics: Adenosine Diphosphate; Adult; Aged; Aspirin; Blood Pressure; Double-Blind Method; Female; Humans; Male; Middle Aged; Naphthalenes; Peripheral Arterial Disease; Placebos; Platelet Aggregation; Propionates; Thromboxanes; Time Factors | 2010 |
Platelet isoprostane overproduction in diabetic patients treated with aspirin.
Topics: Aged; Aged, 80 and over; Aspirin; Blood Platelets; Cross-Sectional Studies; Cyclooxygenase Inhibitors; Diabetes Mellitus, Type 2; Female; Humans; Isoprostanes; Male; Membrane Glycoproteins; Middle Aged; NADPH Oxidase 2; NADPH Oxidases; Thromboxanes | 2012 |
Aspirin attenuates platelet activation and immune activation in HIV-1-infected subjects on antiretroviral therapy: a pilot study.
Topics: Adenosine Diphosphate; Adult; Aged; Anti-HIV Agents; Arachidonic Acid; Aspirin; Cells, Cultured; Collagen; Female; HIV Infections; HIV-1; Humans; Inflammation; Lymphocyte Activation; Male; Middle Aged; P-Selectin; Pilot Projects; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Thromboxanes; Young Adult | 2013 |
Effect of acetylsalicylic acid on platelet activation and oxidative profile in a set of Brazilian patients with type 2 diabetes mellitus.
Topics: Aspirin; Brazil; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Oxidative Stress; Platelet Activation; Platelet Aggregation Inhibitors; Thromboxanes | 2015 |
Thromboxane inhibition during concurrent therapy with low-dose aspirin and over-the-counter naproxen sodium.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Naproxen; Platelet Aggregation Inhibitors; Thromboxane B2; Thromboxanes | 2018 |
On-treatment platelet reactivity through the thromboxane A
Topics: Aspirin; Blood Platelets; Clopidogrel; Humans; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Purinergic P2Y Receptor Antagonists; Thromboxanes; Treatment Outcome | 2023 |
Thromboxane biosynthesis in cancer patients and its inhibition by aspirin: a sub-study of the Add-Aspirin trial.
Topics: Aspirin; Biomarkers; Colorectal Neoplasms; Creatinine; Female; Humans; Male; Middle Aged; Thromboxanes | 2023 |
276 other study(ies) available for aspirin and thromboxanes
| Article | Year |
|---|---|
Salicylic acid fails to inhibit generation of thromboxane A2 activity in platelets after in vivo administration to the rat.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Depression, Chemical; Male; Platelet Aggregation; Rats; Salicylates; Thromboxane A2; Thromboxanes; Time Factors | 1978 |
International prostaglandin conference.
Topics: Arachidonic Acids; Aspirin; Asthma; Autacoids; Female; Humans; Male; Prostaglandins; Thromboxanes | 1979 |
Aspirin, thromboxane, and prostacyclin in rats: A dilemma resolved?
Topics: Animals; Aspirin; Blood Platelets; Blood Vessels; Epoprostenol; Male; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandins; Rats; Thromboxane A2; Thromboxanes | 1978 |
Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway.
Topics: Antilymphocyte Serum; Arachidonic Acids; Aspirin; Concanavalin A; Fatty Acids, Unsaturated; Humans; Lipids; Lipoxygenase; Lymphocyte Activation; Phytohemagglutinins; Thromboxane B2; Thromboxanes; Thymidine; Time Factors | 1979 |
9, 11-Azo-12-oxa-15-hydroxyprostanoic acid: a potent thromboxane synthetase inhibitor and a PGH2/TxA2 receptor antagonist.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aspirin; Humans; Microsomes; Oxidoreductases; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Receptors, Cell Surface; Receptors, Prostaglandin; Swine; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes | 1979 |
[Present-day views on the role of blood platelets in hemostasis. I. Role of platelets in primary hemostasis].
Topics: Aspirin; Blood Coagulation Factors; Blood Platelets; Depression, Chemical; Epoprostenol; Hemostasis; Humans; Platelet Aggregation; Thromboxanes | 1978 |
Prostacyclin and thromboxane generating systems in rabbits pretreated with aspirin.
Topics: Animals; Arachidonic Acids; Aspirin; Celiac Artery; Epoprostenol; Female; In Vitro Techniques; Male; Mesenteric Arteries; Platelet Aggregation; Prostaglandins; Rabbits; Thromboxanes | 1978 |
Prostacyclin (PGI2) and thromboxane A2 interaction in vivo. Regulation by aspirin and relationship with anti-thrombotic therapy.
Topics: Animals; Arachidonic Acids; Aspirin; Cats; Dose-Response Relationship, Drug; Drug Interactions; Epoprostenol; Fibrinolytic Agents; Injections, Intravenous; Male; Platelet Aggregation; Prostaglandins; Rabbits; Thromboxane A2; Thromboxanes | 1978 |
Rabbit lung microsomes: a rapid method for assaying simultaneously drug effects on thromboxane and prostacyclin synthesis.
Topics: Animals; Arachidonic Acids; Aspirin; Burimamide; Dipyridamole; Epoprostenol; Hydralazine; Imidazoles; Indomethacin; Lung; Microsomes; Prostaglandins; Rabbits; Thromboxanes | 1979 |
Prostacyclin, thromboxane A2 interactions in haemostasis and thrombosis.
Topics: Animals; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Epoprostenol; Humans; Platelet Aggregation; Prostaglandins; Thrombosis; Thromboxane A2; Thromboxanes | 1979 |
Thromboxane synthesis and platelet protein release during simulated extracorporeal circulation.
Topics: Aspirin; Blood Platelets; Blood Proteins; Extracorporeal Circulation; Humans; Thromboxanes | 1979 |
Phenylbutazone inhibition of equine platelet function.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Horses; Malondialdehyde; Phenylbutazone; Platelet Aggregation; Prostaglandins; Thrombin; Thromboxanes | 1979 |
Platelet aggregability, thromboxane A2 and malonaldehyde formation following administration of aspirin to man.
Topics: Adult; Arachidonic Acids; Aspirin; Blood Platelets; Coronary Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Malonates; Malondialdehyde; Middle Aged; Myocardial Infarction; Platelet Aggregation; Thromboxane A2; Thromboxanes | 1979 |
Inhibition of thromboxane B2 and 6-ketoprostaglandin F1 alpha formation by anti-inflammatory drugs in carrageenin-induced granuloma.
Topics: Animals; Arachidonic Acids; Aspirin; Carrageenan; Depression, Chemical; Granuloma; Hydrocortisone; In Vitro Techniques; Indomethacin; Male; Prostaglandins F; Rats; Thromboxane B2; Thromboxanes | 1978 |
[Development of myocardial infarction in aspirin-treated unstable angina pectoris. Repeated studies of platelet aggregation and of the thromboxane-prostacyclin system].
Topics: Adult; Angina, Unstable; Aspirin; Epoprostenol; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Thromboxanes | 1992 |
Study of thromboxane and prostacyclin metabolism in an in vitro model of first-trimester human trophoblast.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Aspirin; Chorionic Villi; Epoprostenol; Female; Humans; Karyotyping; Pregnancy; Pregnancy Trimester, First; Thromboxane B2; Thromboxanes; Trophoblasts | 1992 |
Low-dose aspirin inhibits lipid peroxides and thromboxane but not prostacyclin in pregnant women.
Topics: Aspirin; Epoprostenol; Female; Humans; Lipid Peroxides; Pre-Eclampsia; Pregnancy; Radioimmunoassay; Thromboxanes | 1992 |
Evidence of increased platelet activation after thrombolysis in patients with acute myocardial infarction.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Activation; Streptokinase; Thrombolytic Therapy; Thromboxane B2; Thromboxanes | 1992 |
Platelet regulatory prostanoids and platelet release products in sickle cell disease.
Topics: Adolescent; Anemia, Sickle Cell; Aspirin; beta-Thromboglobulin; Blood Platelets; Epoprostenol; Humans; Longitudinal Studies; Meperidine; Prospective Studies; Thromboxanes | 1992 |
High-dose aspirin inhibits shear-induced platelet reaction involving thrombin generation.
Topics: Aspirin; Coronary Artery Bypass; Dose-Response Relationship, Drug; Female; Hemostasis; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Postoperative Complications; Thrombin; Thrombosis; Thromboxanes | 1992 |
Erythrocytes metabolically enhance collagen-induced platelet responsiveness via increased thromboxane production, adenosine diphosphate release, and recruitment.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Aspirin; beta-Thromboglobulin; Blood Platelets; Collagen; Erythrocytes; Female; Humans; Male; Middle Aged; P-Selectin; Platelet Membrane Glycoproteins; Serotonin; Thromboxane A2; Thromboxane B2; Thromboxanes | 1991 |
Urinary excretion of thromboxane and prostacyclin metabolites during chronic low-dose aspirin: evidence for an extrarenal origin of urinary thromboxane B2 and 6-keto-prostaglandin F1 alpha in healthy subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Epoprostenol; Humans; Male; Thromboxane B2; Thromboxanes; Urine | 1992 |
[The effect of decreased thromboxane synthesis on proliferative glomerulonephritis].
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Chronic Disease; Creatinine; Female; Glomerular Filtration Rate; Glomerulonephritis; Humans; Male; Middle Aged; Proteinuria; Thromboxanes | 1991 |
Protective effects of the novel thromboxane A2 receptor antagonist sodium (E)-11-[2-(5,6-dimethyl-1-benzimidazolyl)-ethylidene]-6,11- dihydrodibenz[b,e]oxepine-2-carboxylate monohydrate against 9,11-dideoxy- 9 alpha, 11 alpha-epoxymethano-prostaglandin F2
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aspirin; Benzimidazoles; Benzoxepins; Blood Pressure; Death, Sudden; Dose-Response Relationship, Drug; Guinea Pigs; Male; Phenylacetates; Platelet Aggregation Inhibitors; Platelet Count; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Sulfonamides; Thromboxane A2; Thromboxanes; Ticlopidine | 1991 |
Lung vascular injury after administration of viable hemolysin-forming Escherichia coli in isolated rabbit lungs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Pressure; Capillary Permeability; Epoprostenol; Escherichia coli; Female; Hemolysin Proteins; Hypertension, Pulmonary; In Vitro Techniques; L-Lactate Dehydrogenase; Lung; Male; Neutrophils; Perfusion; Potassium; Pulmonary Artery; Rabbits; Receptors, Prostaglandin; Receptors, Thromboxane; Respiratory Insufficiency; Sulfonamides; Thromboxane B2; Thromboxanes | 1991 |
Suppression of eicosanoid biosynthesis during coronary angioplasty by fish oil and aspirin.
Topics: Angioplasty, Balloon, Coronary; Aspirin; Chest Pain; Eicosanoids; Epoprostenol; Fish Oils; Humans; Male; Patient Compliance; Thromboxane A2; Thromboxanes | 1991 |
In vitro antiplatelet profiles of the new thromboxane synthetase inhibitor sodium 2-(1-imidazolylmethyl)-4,5-dihydrobenzo[b]thiophene-6-carboxylate.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Aspirin; Dogs; Humans; Imidazoles; In Vitro Techniques; Male; Methacrylates; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thiophenes; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1991 |
Aspirin-induced decline in prostacyclin production in patients with coronary artery disease is due to decreased endoperoxide shift. Analysis of the effects of a combination of aspirin and n-3 fatty acids on the eicosanoid profile.
Topics: Aged; Arachidonic Acid; Aspirin; Coronary Disease; Eicosanoids; Eicosapentaenoic Acid; Epoprostenol; Female; Fish Oils; Humans; Male; Middle Aged; Phospholipids; Prostaglandin Endoperoxides; Thromboxanes | 1991 |
Heart disease, aspirin, and fish oil.
Topics: Aspirin; Coronary Disease; Epoprostenol; Fatty Acids; Fish Oils; Humans; Thromboxanes | 1991 |
Thromboxane biosynthesis and platelet function in type II diabetes mellitus.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Blood Platelets; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Platelet Aggregation; Thromboxane A2; Thromboxane B2; Thromboxanes | 1990 |
Effects of aspirin on xylazine-induced hypoxaemia in sheep.
Topics: Animals; Aspirin; Female; Hypoxia; Injections, Intravenous; Male; Oxygen; Platelet Aggregation; Platelet Count; Sheep; Sheep Diseases; Thiazines; Thromboxanes; Xylazine | 1990 |
Activation of platelets induced by mAb P256 specific for glycoprotein IIb-IIIa. Possible evidence for a role for IIb-IIIa in membrane signal transduction.
Topics: Animals; Antibodies, Monoclonal; Aspirin; Autoradiography; Binding Sites; Calcium; Immunoglobulin G; Mice; Phosphatidic Acids; Phospholipids; Phosphorylation; Platelet Aggregation; Platelet Membrane Glycoproteins; Signal Transduction; Thromboxanes | 1990 |
Low dose ASA (4 mg/kg) peroperatively does not prevent in vivo platelet accumulation at microarterial anastomotic sites. An experimental study in the rabbit.
Topics: Anastomosis, Surgical; Animals; Arteries; Aspirin; Dose-Response Relationship, Drug; Ear; Phosphorus Radioisotopes; Platelet Aggregation; Rabbits; Rats; Thromboxanes | 1990 |
Role of eicosanoids in the kappa-carrageenin rat tail thrombosis.
Topics: Aminopyrine; Animals; Aspirin; Benzydamine; Cardiovascular Agents; Carrageenan; Diclofenac; Epoprostenol; Female; Iloprost; Imidazoles; Phenylbutazone; Rats; Rats, Inbred Strains; Thrombosis; Thromboxanes; Trapidil | 1988 |
[Acetylsalicylic acid and myocardial infarction. Intermittent dosage means intact production of prostacyclin].
Topics: Aged; Aspirin; Epoprostenol; Female; Humans; Male; Middle Aged; Myocardial Infarction; Thromboxanes | 1989 |
Thromboxane is produced in response to intracoronary infusions of complement C5a in pigs. Cyclooxygenase blockade does not reduce the myocardial ischemia and leukocyte accumulation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aspirin; Complement C5a; Coronary Disease; Coronary Vessels; Cyclooxygenase Inhibitors; Female; Indomethacin; Injections, Intra-Arterial; Leukocyte Count; Leukocytes; Male; Myocardium; Prostaglandin Endoperoxides, Synthetic; Swine; Thromboxane B2; Thromboxanes | 1989 |
Superior antiplatelet action of alternate day pulsed dosing versus split dose administration of aspirin.
Topics: Aspirin; Blood Coagulation; Dose-Response Relationship, Drug; Epoprostenol; Humans; Platelet Aggregation Inhibitors; Thromboxanes | 1989 |
Aspirin differentially affects thromboxane and prostacyclin production by trophoblast and villous core compartments of human placental villi.
Topics: Aspirin; Chorionic Villi; Epoprostenol; Female; Humans; Pregnancy; Pregnancy Trimester, Third; Thromboxanes; Trophoblasts | 1989 |
Measurement of aspirin concentrations in portal and systemic blood in pigs: effect on platelet aggregation, thromboxane and prostacyclin production.
Topics: Animals; Aspirin; Blood Platelets; Epoprostenol; Platelet Aggregation Inhibitors; Swine; Thromboxanes | 1989 |
Thromboxane production in placentas of women with preeclampsia.
Topics: Aspirin; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy; Thromboxane A2; Thromboxanes | 1989 |
Effects of L-652,731, a platelet-activating factor (PAF) receptor antagonist, on PAF- and complement-induced pulmonary hypertension in sheep.
Topics: Animals; Aspirin; Complement Activation; Complement System Proteins; Dose-Response Relationship, Drug; Endotoxins; Female; Furans; Hypertension, Pulmonary; Hypoxia; Neutropenia; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sheep; Thromboxanes; Zymosan | 1987 |
Allergic rhinitis relieved by aspirin and other nonsteroidal antinflammatory drugs.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclic AMP; Double-Blind Method; Humans; Immunoglobulin E; Male; Nasal Mucosa; Platelet Aggregation; Rhinitis, Allergic, Perennial; T-Lymphocytes, Regulatory; Thromboxanes | 1988 |
Growth hormone-releasing factor (GRF) stimulates PGE2 production in rat anterior pituitary. Evidence for a PGE2 involvement in GRF-induced GH release.
Topics: Animals; Aspirin; Dinoprostone; Growth Hormone; Growth Hormone-Releasing Hormone; In Vitro Techniques; Indomethacin; Male; Pituitary Gland, Anterior; Prostaglandins; Prostaglandins E; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Thromboxanes | 1985 |
Hypersensitivity to methoxamine in atria isolated from streptozotocin-induced diabetic rats.
Topics: Adrenergic alpha-Antagonists; Animals; Aspirin; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Epoprostenol; Heart Atria; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Methoxamine; Myocardial Contraction; Rats; Rats, Inbred Strains; Thromboxanes | 1986 |
[Effect of the complex treatment of stable stenocardia on the status of the prostacyclin-thromboxane system].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Aspirin; Dipyridamole; Drug Therapy, Combination; Epoprostenol; Humans; In Vitro Techniques; Male; Middle Aged; Nitrates; Platelet Aggregation; Thromboxanes | 1986 |
Aspirin, infarction, and platelet/vessel-wall interactions.
Topics: Aspirin; Blood Platelets; Endothelium, Vascular; Epoprostenol; Humans; Myocardial Infarction; Thromboxanes | 1988 |
[Role of prostaglandins and thromboxanes in cardiovascular physiopathology].
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Cardiovascular System; Enzyme Inhibitors; Humans; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxanes; Vasoconstrictor Agents; Vasodilator Agents | 1985 |
Analysis of multiple thromboxane metabolites in plasma and urine.
Topics: Aspirin; Humans; Thromboxane B2; Thromboxanes; Vascular Diseases | 1987 |
Comparison of the effects of some compounds on human neutrophil degranulation and leukotriene B4 and thromboxane B2 synthesis.
Topics: Arachidonic Acids; Aspirin; Calcimycin; Humans; In Vitro Techniques; Indomethacin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenylbutazone; Thromboxane B2; Thromboxanes | 1985 |
Thromboxane- and ADP-independent aggregation and exposure of fibrinogen receptors on platelets from patients with familial hypercholesterolemia.
Topics: Adenosine Diphosphate; Adolescent; Adult; Apyrase; Aspirin; Child; Female; Humans; Hyperlipoproteinemia Type II; Male; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Thromboxanes | 1985 |
The response of human carcinoma cell lines to gamma-linolenic acid with special reference to the effects of agents which influence prostaglandin and thromboxane synthesis.
Topics: Alprostadil; Aspirin; Cell Division; Cell Line; Cell Survival; gamma-Linolenic Acid; Humans; Imidazoles; Indomethacin; Linolenic Acids; Neoplasms; Prostaglandins; Prostaglandins E; Thromboxane A2; Thromboxanes | 1985 |
The role of arachidonic acid metabolites in preeclampsia.
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Epoprostenol; Female; Hemodynamics; Humans; Leukotriene B4; Lipoxygenase; Maternal-Fetal Exchange; Pre-Eclampsia; Pregnancy; Prostaglandins E; Prostaglandins F; Thromboxanes; Trophoblasts | 1986 |
Effect of aspirin and sulindac in rabbit nephrotoxic nephritis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Basement Membrane; Blood Platelets; Cyclooxygenase Inhibitors; Indenes; Kidney Glomerulus; Male; Nephritis; Prostaglandins; Rabbits; Sulindac; Thromboxanes | 1986 |
Platelet aggregation and thromboxane release induced by arachidonic acid, collagen, ADP and platelet-activating factor following low dose acetylsalicylic acid in man.
Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Activating Factor; Platelet Aggregation; Thromboxane B2; Thromboxanes | 1986 |
Platelets and prostaglandins.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Humans; Migraine Disorders; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxanes | 1986 |
Arachidonic acid metabolites during nasal challenge.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Female; Histamine; Humans; Male; Nasal Provocation Tests; Peptide Hydrolases; Premedication; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Rhinitis, Allergic, Seasonal; Sneezing; SRS-A; Thromboxanes | 1987 |
Prolongation of rat cardiac allograft survival with arachidonic acid metabolism inhibitor.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Aspirin; Graft Survival; Heart Transplantation; Lysine; Male; Methacrylates; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Thromboxane B2; Thromboxanes; Transplantation, Homologous | 1987 |
Eicosanoids and aspirin-sensitive asthma.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Blood Platelets; Humans; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxane A2; Thromboxanes | 1987 |
Effects of the prostaglandin H2/thromboxane A2 antagonist BM 13.177 on human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Blood Platelets; Collagen; Humans; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Serotonin; Sulfonamides; Thrombin; Thromboxane A2; Thromboxanes | 1985 |
Does non-acetylated salicylate inhibit thromboxane biosynthesis in human platelets?
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Blood Platelets; Choline; Double-Blind Method; Humans; Male; Random Allocation; Salicylates; Thromboxanes | 1988 |
Prolongation of bleeding time by aspirin: a dual mechanism?
Topics: Acetylcholine; Aspirin; Biological Products; Bleeding Time; Humans; Nitric Oxide; Platelet Function Tests; Prostaglandin Antagonists; Thromboxanes; Vasodilator Agents | 1988 |
A rapid assay for platelet thromboxane production and its use in assessing prior aspirin ingestion.
Topics: Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Humans; Thromboxanes; Time Factors | 1988 |
Inhibition of platelet aggregation and thromboxane production by low concentrations of aspirin in vitro.
Topics: Aspirin; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Platelet Aggregation; Thromboxanes | 1988 |
The absorption of acetylsalicylic acid from an enteric-coated formulation and the inhibition of thromboxane formation.
Topics: Adult; Aspirin; Depression, Chemical; Female; Half-Life; Humans; Intestinal Absorption; Male; Salicylates; Salicylic Acid; Tablets; Tablets, Enteric-Coated; Thromboxane B2; Thromboxanes | 1988 |
Influence of anti-platelet drugs on platelet-vessel wall interactions.
Topics: Aspirin; Calcium Channel Blockers; Endothelium, Vascular; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Thromboxanes | 1987 |
11-Dehydrothromboxane B2: a quantitative index of thromboxane A2 formation in the human circulation.
Topics: Aspirin; Humans; Kinetics; Platelet Aggregation; Thromboxane B2; Thromboxanes; Time Factors | 1986 |
The effects of metamizol on prostaglandin synthesis in man.
Topics: Alprostadil; Aminopyrine; Aspirin; Collagen; Dinoprostone; Dipyrone; Gastric Juice; Gastric Mucosa; Humans; In Vitro Techniques; Indomethacin; Kidney; Kinetics; Platelet Aggregation; Prostaglandins; Prostaglandins E; Thromboxanes | 1986 |
Maternal ingestion of acetylsalicylic acid inhibits fetal and neonatal prostacyclin and thromboxane in humans.
Topics: Adult; Aspirin; Epoprostenol; Female; Fetal Blood; Humans; Infant, Newborn; Pregnancy; Thromboxane A2; Thromboxane B2; Thromboxanes | 1986 |
Different effects of aspirin, dipyridamole and UD-CG 115 on platelet activation in a model of vascular injury: studies with extracellular matrix covered with endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Cattle; Cells, Cultured; Dipyridamole; Endothelium; Epoprostenol; Extracellular Matrix; Humans; Models, Biological; Platelet Aggregation; Pyridazines; Thromboxanes | 1986 |
Speculation regarding mechanisms responsible for acute ischemic heart disease syndromes.
Topics: Angina, Unstable; Animals; Aspirin; Coronary Circulation; Coronary Disease; Coronary Vasospasm; Dogs; Humans; Platelet Aggregation; Prostaglandins; Serotonin; Syndrome; Thromboxanes | 1986 |
Cumulative inhibitory effect of low-dose aspirin on vascular prostacyclin and platelet thromboxane production in patients with atherosclerosis.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Blood Platelets; Blood Vessels; Coronary Disease; Epoprostenol; Humans; Male; Middle Aged; Platelet Aggregation; Thromboxane A2; Thromboxanes | 1985 |
[Effects of sodium ferulate combined with acetylsalicylic acid on rat platelet aggregation and on modulation of PGI2-TXA2 balance].
Topics: Animals; Anticoagulants; Aspirin; Cinnamates; Coumaric Acids; Drug Synergism; Epoprostenol; Male; Platelet Aggregation; Rabbits; Rats; Thromboxane A2; Thromboxanes | 1985 |
Effects of aspirin and alcohol on platelet thromboxane synthesis and vascular prostacyclin synthesis.
Topics: Aspirin; Blood Platelets; Epoprostenol; Ethanol; Female; Humans; Kinetics; Muscle, Smooth, Vascular; Pregnancy; Thromboxanes; Umbilical Arteries | 1985 |
Duration of the effect of aspirin on the synthesis of thromboxane by density subpopulations of rabbit platelets stimulated with thrombin.
Topics: Animals; Aspirin; Blood Platelets; Cell Separation; Prostaglandin-Endoperoxide Synthases; Rabbits; Thrombin; Thromboxane B2; Thromboxanes; Time Factors | 1985 |
Differential effects of aspirin and indomethacin on platelet and leukocyte thromboxane A2 formation.
Topics: Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Indomethacin; Leukocytes; Prostaglandin-Endoperoxide Synthases; Thromboxane A2; Thromboxanes | 1985 |
Long-term ultra-low-dose aspirin therapy and platelet function.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Bleeding Time; Collagen; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Male; Platelet Aggregation; Thromboxane B2; Thromboxanes; Time Factors | 1985 |
Thromboxane production by perturbed bovine aortic endothelial cells in culture.
Topics: Animals; Aorta; Aspirin; Cattle; Cells, Cultured; Clone Cells; Cycloheximide; Dactinomycin; Endothelium; Endotoxins; Imidazoles; Thromboxane B2; Thromboxanes; Time Factors | 1985 |
Selective inhibition of thromboxane-related platelet function by low-dose aspirin in patients after myocardial infarction.
Topics: Aged; Aspirin; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Thromboxane A2; Thromboxanes | 1985 |
Inhibition of platelet aggregation and thromboxane B2 production during aspirin treatment: dependence on the dose of the aggregating agent.
Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Male; Platelet Aggregation; Thromboxane B2; Thromboxanes | 1985 |
Lack of effect of glucocorticoids upon plasma thromboxane in patients in a state of shock.
Topics: Aspirin; Blood Coagulation; Glucocorticoids; Humans; Methylprednisolone; Oxygen; Oxygen Consumption; Radioimmunoassay; Shock, Septic; Thromboxane B2; Thromboxanes | 1985 |
Inhibition of human platelet thromboxane generation by aspirin in the absence of measurable drug levels in peripheral blood.
Topics: Adult; Aspirin; Blood Platelets; Depression, Chemical; Humans; Male; Salicylates; Salicylic Acid; Thromboxanes | 1985 |
Contribution of circulating formed elements to prostanoid production in complement-mediated lung injury in sheep.
Topics: Animals; Aspirin; Complement Activation; Cross Circulation; Female; Leukocyte Transfusion; Lung; Lung Diseases; Plasma; Platelet Transfusion; Prostaglandins; Sheep; Thromboxanes; Zymosan | 1985 |
Heparin-induced platelet aggregation is inhibited by antagonists of the thromboxane pathway.
Topics: Aspirin; Bleeding Time; Heparin; Heparin Antagonists; Humans; Indomethacin; Platelet Aggregation; Prostanoic Acids; Thromboxanes | 1985 |
Platelet accumulation on collagen: drugs which inhibit arachidonic acid metabolism and affect intracellular cyclic AMP levels.
Topics: Alprostadil; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Cyclic AMP; Humans; In Vitro Techniques; Indomethacin; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins; Prostaglandins E; Thromboxanes | 1984 |
Congenital deficiency of thromboxane and prostacyclin.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acids; Aspirin; Blood Coagulation Tests; Blood Platelet Disorders; Cells, Cultured; Chromatography, Thin Layer; Epoprostenol; Hemorrhage; Humans; Male; Oxygenases; Plasma; Platelet Aggregation; Prostaglandins; Thromboxane A2; Thromboxanes | 1980 |
Aspirin inhibition of thromboxane release in thrombosis and renal transplant rejection.
Topics: Aspirin; Graft Rejection; Humans; Kidney Transplantation; Thrombophlebitis; Thromboxane B2; Thromboxanes | 1982 |
Thromboxane A2 in skin-bleeding-time blood and in clotted venous blood before and after administration of acetylsalicylic acid.
Topics: Adenosine Diphosphate; Adult; Aspirin; Bleeding Time; England; Hemorrhage; Hemostasis; Humans; Male; Platelet Aggregation; Platelet Function Tests; Skin; Sweden; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
Role of lipoxygenases in regulation of PHA and phorbol ester-induced mitogenesis.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Lipoxygenase; Lymphocyte Activation; Lymphocytes; Mice; Phorbols; Phytohemagglutinins; Tetradecanoylphorbol Acetate; Thromboxanes | 1982 |
Aspirin inhibits endogenous prostacyclin and thromboxane biosynthesis in man.
Topics: Aspirin; Humans; Kinetics; Prostaglandins F, Synthetic; Thromboxane B2; Thromboxanes | 1983 |
Evidence for a renal origin of urinary thromboxane B2 in health and disease.
Topics: Adult; Aspirin; Blood Platelets; Female; Glomerulonephritis; Humans; Kidney; Kinetics; Reference Values; Sulindac; Thromboxane B2; Thromboxanes | 1983 |
Prostaglandins and angioplasty. An experimental study in canine arteries.
Topics: Angioplasty, Balloon; Animals; Aspirin; Carotid Arteries; Cyclooxygenase Inhibitors; Dogs; Epoprostenol; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Platelet Aggregation; Thromboxane A2; Thromboxanes | 1983 |
Interrelationships between prostacyclin and thromboxane A2.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Cardiovascular Physiological Phenomena; Cardiovascular System; Cyclic AMP; Epoprostenol; Heart; Humans; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins; Pulmonary Circulation; Thromboxane A2; Thromboxanes; Vasodilation | 1980 |
Prostacyclin-thromboxane interactions in the platelet-perfused in vitro heart.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Blood Pressure; Cyclic AMP; Epoprostenol; Female; Guinea Pigs; Heart; Humans; In Vitro Techniques; Kinetics; Male; Perfusion; Prostaglandins; Thromboxane A2; Thromboxanes | 1981 |
Strontium ions induce production of thromboxane B2 and secretion of 5-hydroxytryptamine in washed human platelets.
Topics: Aspirin; Blood Platelets; Bucladesine; Humans; Prostaglandins E; Serotonin; Strontium; Thromboxane B2; Thromboxanes | 1981 |
A role for prostaglandins and thromboxanes in the exposure of platelet fibrinogen receptors.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Epinephrine; Fibrinogen; Humans; Indomethacin; Platelet Aggregation; Platelet Membrane Glycoproteins; Prostaglandins; Prostaglandins A; Prostaglandins H; Receptors, Cell Surface; Thromboxanes | 1981 |
Effects of stimulators and inhibitors on arachidonic acid metabolism in hepatoma.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Butylated Hydroxytoluene; Carcinoma, Hepatocellular; Indomethacin; Liver Neoplasms; Prostaglandins; Rats; Sodium Salicylate; Thromboxane B2; Thromboxanes; Tryptophan | 1981 |
Platelet aggregation and thromboxane A2 production after adrenergic stimulation in young healthy humans.
Topics: Adolescent; Adult; Aspirin; beta-Thromboglobulin; Cold Temperature; Female; Humans; Male; Platelet Aggregation; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thromboxane A2; Thromboxane B2; Thromboxanes; Vascular Resistance | 1982 |
Evidence for a mediator role of thromboxane A2 in the myotropic action of leukotriene B4 (LTB4) on the guinea-pig lung.
Topics: Animals; Arachidonic Acids; Aspirin; Female; Flufenamic Acid; Guinea Pigs; Imidazoles; Indoles; Leukotriene B4; Leukotrienes; Lipid Peroxides; Lung; Male; Muscle Contraction; Peroxides; Prostaglandins; Pyridines; Quinacrine; Thromboxane A2; Thromboxane B2; Thromboxanes | 1982 |
Reduced platelet thromboxane formation in uremia. Evidence for a functional cyclooxygenase defect.
Topics: Adult; Aged; Arachidonic Acids; Aspirin; Blood Platelets; Cyclic AMP; Female; Humans; Male; Middle Aged; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Thromboxanes; Uremia | 1983 |
[The Nobel Prize for Medicine 1982. On essential fatty acids, prostaglandins and acetylsalicylic acid].
Topics: Aspirin; Humans; Leukotriene B4; Prostaglandin Antagonists; Prostaglandins; Thromboxanes | 1983 |
Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man.
Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Platelets; Epoprostenol; Humans; Male; Platelet Aggregation; Prostaglandins; Radioimmunoassay; Thromboxanes | 1983 |
[Surveillance of treatment with antiaggregating agents].
Topics: Aspirin; Blood Coagulation Tests; Dipyridamole; Epoprostenol; Humans; Platelet Aggregation; Prostaglandins; Thromboxane A2; Thromboxanes | 1983 |
Modulation of cardiovascular function and platelet survival by endogenous prostacyclin released during surgery.
Topics: Aged; Animals; Aorta, Abdominal; Aortic Aneurysm; Aspirin; Blood Platelets; Cell Survival; Dogs; Epoprostenol; Female; Hemodynamics; Humans; Indomethacin; Intraoperative Period; Male; Platelet Aggregation; Platelet Count; Prostaglandins; Surgical Procedures, Operative; Thromboxanes | 1983 |
The stimulatory effect of prostacyclin (PGI2) on isolated rabbit and rat aorta is probably associated to the generation of a thromboxane A2 (TXA2) "like-material".
Topics: Adenosine Diphosphate; Animals; Aorta, Thoracic; Aspirin; Corticosterone; Epoprostenol; Imidazoles; In Vitro Techniques; Indomethacin; Male; Prostaglandins; Rabbits; Rats; Species Specificity; Thromboxane A2; Thromboxanes; Vasoconstriction | 1983 |
The antithrombotic effect of aspirin and dipyridamole in relation to prostaglandin synthesis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Dipyridamole; Epoprostenol; Fibrinolytic Agents; Male; Prostaglandins; Rabbits; Thrombosis; Thromboxanes | 1983 |
[Blood thromboxane A2 and prostaglandin I2 levels and platelet phospholipid fatty acid composition ratios in ischemic heart disease and cerebral infarction--with special reference to the effect of antiplatelet agents].
Topics: Aged; Aspirin; Blood Platelets; Cerebral Infarction; Coronary Disease; Dipyridamole; Epoprostenol; Fatty Acids; Female; Humans; Male; Middle Aged; Phospholipids; Thromboxane A2; Thromboxanes; Trapidil | 1983 |
Selective and nonselective inhibition of thromboxane formation.
Topics: Aspirin; Blood Platelets; Collagen; Epoprostenol; Humans; Imidazoles; Male; Pyridines; Random Allocation; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1984 |
Platelet function and biosynthesis of prostacyclin and thromboxane A2 in whole blood after aspirin administration in human subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Triphosphate; Adult; Aspirin; Blood Platelets; Epoprostenol; Female; Humans; Male; Platelet Aggregation; Thromboxane A2; Thromboxanes | 1984 |
Prostanoid synthesis by aortic rings in human blood: selective increase of prostacyclin mediated by a serum factor.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Aspirin; Citrates; Epoprostenol; Humans; In Vitro Techniques; Male; Methacrylates; Muscle, Smooth, Vascular; Prostaglandins; Radioimmunoassay; Rats; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1984 |
Sequential histamine inhalations cause increased bronchial histamine reactivity in guinea pigs: role of platelets, thromboxanes and prostacyclin.
Topics: Animals; Aspirin; Blood Platelets; Bronchi; Bronchial Provocation Tests; Chemical Phenomena; Chemistry; Cimetidine; Epoprostenol; Guinea Pigs; Histamine; Imidazoles; Male; Platelet Aggregation; Pyridines; Receptors, Histamine H1; Receptors, Histamine H2; Thromboxane-A Synthase; Thromboxanes | 1984 |
Human vascular tissues produce thromboxane as well as prostacyclin.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Epoprostenol; Female; Humans; Mammary Arteries; Middle Aged; Muscle, Smooth, Vascular; Pregnancy; Prostaglandins; Saphenous Vein; Thromboxane A2; Thromboxanes; Umbilical Arteries; Umbilical Veins | 1983 |
Role of thromboxanes in vasotonic versus vaso-occlusive angina.
Topics: Angina Pectoris; Angina Pectoris, Variant; Arterial Occlusive Diseases; Aspirin; Blood Platelets; Cardiac Pacing, Artificial; Coronary Disease; Coronary Vasospasm; Heparin; Humans; Lactates; Thromboxane B2; Thromboxanes | 1983 |
The role of ADP secretion and thromboxane synthesis in factor VIII binding to platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Apyrase; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Factor VIII; Humans; Prostaglandin Endoperoxides, Synthetic; Thrombin; Thromboxane A2; Thromboxanes | 1983 |
Thromboxane A2 generation by the larval cestode, Taenia taeniaeformis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Horses; Imidazoles; Indomethacin; Kinetics; Larva; Platelet Aggregation; Rats; Taeniasis; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
Effects of ASA on thromboxane and prostacyclin synthesis by rabbit aorta and pulmonary artery.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Aspirin; Cyclooxygenase Inhibitors; Epoprostenol; Female; In Vitro Techniques; Prostaglandins; Pulmonary Artery; Rabbits; Thromboxane A2; Thromboxane B2; Thromboxanes; Time Factors | 1983 |
The effect of two low doses of aspirin on whole blood thromboxane and prostacyclin generation in healthy subjects.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Coagulation; Cyclooxygenase Inhibitors; Epoprostenol; Female; Humans; Male; Thromboxane B2; Thromboxanes; Time Factors | 1983 |
Prostaglandins and related compounds -- a general physiologic control system.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Diet; Epoprostenol; Fatty Acids; Female; Humans; Indomethacin; Pregnancy; Prostaglandins; SRS-A; Thromboxane A2; Thromboxanes | 1983 |
[Divergence between the pharmacologic and clinical effects of inhibitors of prostaglandin synthesis].
Topics: Aspirin; Blood Platelets; Dipyridamole; Drug Interactions; Epoprostenol; Humans; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid; Sulfinpyrazone; Thrombosis; Thromboxanes | 1984 |
Reversible inhibition of thromboxane A2 production by imidazole 2-hydroxybenzoate (ITF 182) in the arachidonic acid injected rat. A comparison with acetylsalicylic acid and indometacin.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Imidazoles; Indomethacin; Injections, Intravenous; Male; Prostaglandins; Rats; Rats, Inbred Strains; Salicylates; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes | 1984 |
Prostaglandin endoperoxides and thromboxane A2 in thrombus formation in the hamster cheek pouch in vivo.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cheek; Cricetinae; Cyclooxygenase Inhibitors; Dipyridamole; Epoprostenol; Male; Mesocricetus; Microscopy, Electron; Platelet Aggregation; Sulfinpyrazone; Thrombosis; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1984 |
Role of eicosanoids in the control of renal function in severe hepatic disease.
Topics: Animals; Arachidonic Acids; Aspirin; Dogs; Humans; Ibuprofen; Indomethacin; Kidney; Lipoxygenase; Liver Cirrhosis; Phospholipases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Regional Blood Flow; Thromboxanes; Vasoconstriction | 1984 |
Mechanism of nitroglycerin-induced coronary dilatation: lack of relation to intracoronary thromboxane concentrations.
Topics: Adult; Aged; Aspirin; Coronary Circulation; Coronary Disease; Coronary Vessels; Female; Humans; Male; Middle Aged; Nitroglycerin; Thromboxane A2; Thromboxane B2; Thromboxanes; Vasodilation | 1984 |
[Thrombocyte interaction with a collagen substrate: the role of thrombocyte-synthesized prostaglandin endoperoxides and thromboxane A2].
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Humans; Microscopy, Electron, Scanning; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Thrombosis; Thromboxane A2; Thromboxanes | 1984 |
Platelet prostanoids in interaction of platelets with collagen substrates. II. Effects of exogenous arachidonic acid, stable PG endoperoxides analogue, and aspirin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cattle; Collagen; Humans; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Thrombin; Thromboxanes | 1984 |
The potential role of thromboxane and prostacyclin in endotoxic and septic shock.
Topics: Animals; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Epoprostenol; Fatty Acids; Gentamicins; Ibuprofen; Imidazoles; Methacrylates; Peritonitis; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane-A Synthase; Thromboxanes | 1984 |
One milligramme of acetylsalicylic acid daily inhibits platelet thromboxane A2 production.
Topics: Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Humans; Platelet Count; Thromboxane A2; Thromboxanes | 1984 |
Urinary excretion of 2,3-dinor-thromboxane B2 in man under normal conditions, following drugs and during some pathological conditions.
Topics: Acetaminophen; Adult; Amino Acid Metabolism, Inborn Errors; Aspirin; Circadian Rhythm; Diabetes Mellitus; Female; Humans; Indomethacin; Male; Myocardial Infarction; Physical Exertion; Pregnancy; Reference Values; Thromboxane B2; Thromboxanes | 1984 |
Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Charcoal; Hemoperfusion; Heparin; Humans; Kidney Failure, Chronic; Middle Aged; Platelet Count; Thromboxane B2; Thromboxanes | 1983 |
Effect of prolonged treatment with acetylsalicylic acid and dipyridamole on platelet thromboxane A2 production in atherosclerotic subjects.
Topics: Aged; Arteriosclerosis; Aspirin; Blood Platelets; Dipyridamole; Female; Humans; Kinetics; Male; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom.
Topics: Animals; Aspirin; Dinoprost; Drug Interactions; Fibrinolytic Agents; Functional Laterality; Imidazoles; Kinetics; Male; Prostaglandins F; Pyrazoles; Pyrazolones; Rabbits; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1983 |
Salicylate does not interfere with aspirin in human blood in vivo.
Topics: Adult; Aspirin; Blood Coagulation; Blood Platelets; Humans; Male; Salicylates; Salicylic Acid; Thromboxane B2; Thromboxanes | 1984 |
Prostaglandins in peptic ulcer disease: effect of nonsteroidal anti-inflammatory compounds (NOSAC).
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Carbazoles; Duodenal Ulcer; Gastric Mucosa; Humans; Indomethacin; Prostaglandin Antagonists; Prostaglandins; Radioimmunoassay; Stomach Ulcer; Thromboxanes | 1984 |
Leukotriene-induced contraction and thromboxane production in guinea-pig lung parenchymal strips.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Dinoprost; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Muscle Contraction; Muscle, Smooth; Prostaglandins F; SRS-A; Thromboxane A2; Thromboxanes | 1984 |
Thromboxane production in the pregnant rat: differential recovery by platelets and uterus following aspirin administration.
Topics: Animals; Aspirin; Blood Platelets; Female; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxanes; Uterus | 1983 |
Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Complement Activation; Female; Hypertension, Pulmonary; In Vitro Techniques; Leukocytes; Lung; Male; Pulmonary Artery; Sheep; Thrombocytopenia; Thromboxane B2; Thromboxanes | 1983 |
The involvement of prostaglandins and thromboxanes in the response to pulmonary embolism in anaesthetized rabbits and isolated perfused lungs.
Topics: 6-Ketoprostaglandin F1 alpha; Anesthesia, General; Animals; Aspirin; Hypotension; Indomethacin; Lung; Male; Perfusion; Pressure; Pulmonary Artery; Pulmonary Embolism; Rabbits; Thromboxane B2; Thromboxanes | 1983 |
Urinary excretion of thromboxane B2 in patients with venous thromboembolic disease.
Topics: Angiography; Aspirin; Humans; Lung; Platelet Function Tests; Pulmonary Embolism; Radioimmunoassay; Thrombophlebitis; Thromboxane B2; Thromboxanes | 1984 |
Recovery of megakaryocyte thromboxane production in vitro after aspirin inhibition.
Topics: Animals; Aspirin; Blood Platelets; Cells, Cultured; Guinea Pigs; Kinetics; Megakaryocytes; Radioimmunoassay; Thromboxane B2; Thromboxanes | 1984 |
Activation of platelet prostaglandin biosynthesis pathway during neoplastic cell-induced platelet aggregation.
Topics: Animals; Apyrase; Aspirin; Blood Platelets; Cell Line; Cell Transformation, Neoplastic; Fibrosarcoma; Humans; Mice; Platelet Aggregation; Thromboxane B2; Thromboxanes | 1984 |
A study of the bioavailability and platelet inhibitory effects of a new enteric-coated acetylsalicylic acid preparation.
Topics: Aspirin; Biological Availability; Blood Platelets; Collagen; Female; Humans; Male; Tablets, Enteric-Coated; Thromboxane B2; Thromboxanes | 1984 |
[Importance of the knowledge of prostaglandins for the odonto-stomatologist; their role in primary hemostasis and in inflammation].
Topics: Anti-Inflammatory Agents; Anticoagulants; Aspirin; Biochemical Phenomena; Biochemistry; Hemostasis; Humans; Inflammation; Nucleotides, Cyclic; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandins; Thromboxanes | 1984 |
Platelet adherence to collagen: role of prostaglandin-thromboxane synthesis.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Collagen; Dose-Response Relationship, Drug; Humans; Imidazoles; Indomethacin; Magnesium; Middle Aged; Platelet Adhesiveness; Prostaglandins; Serotonin; Temperature; Thromboxanes | 1981 |
Human platelet activation in the absence of aggregation: a calcium-dependent phenomenon independent of thromboxane formation.
Topics: Aspirin; Blood Platelets; Calcimycin; Calcium; Humans; Microscopy, Electron; Platelet Aggregation; Platelet Count; Serotonin; Thromboxane B2; Thromboxanes | 1982 |
Some perspectives on platelets and prostaglandins.
Topics: Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Humans; Platelet Aggregation; Prostaglandin Endoperoxides; Prostaglandins; Thrombin; Thromboxanes | 1981 |
Pharmacologic modulation of arachidonic acid metabolism in man. A minireview with emphasis on radioimmunological methods used to quantitate drug effects.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Humans; In Vitro Techniques; Prostaglandins; Pyrazoles; Radioimmunoassay; Thromboxane-A Synthase; Thromboxanes | 1982 |
Aspirin inhibits rat megakaryocyte thromboxane synthesis.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Humans; Megakaryocytes; Radioimmunoassay; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxanes | 1982 |
Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Aspirin; Male; Methods; Platelet Aggregation; Rats; Rats, Inbred Strains; Salicylates; Thromboxane B2; Thromboxanes | 1982 |
The effect of sulphinpyrazone on whole blood thromboxane and prostacyclin generation in man.
Topics: Adult; Aspirin; Collagen; Cyclooxygenase Inhibitors; Depression, Chemical; Epoprostenol; Humans; Leukocytes; Platelet Aggregation; Prostaglandins; Radioimmunoassay; Stimulation, Chemical; Sulfinpyrazone; Thromboxane A2; Thromboxanes; Time Factors | 1982 |
Comparison of umbilical vein models for measurement of relative prostacyclin and thromboxane production.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Aspirin; Epoprostenol; Humans; Methacrylates; Models, Biological; Prostaglandins; Specimen Handling; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes; Umbilical Veins | 1982 |
Effects of vitamin E and aspirin on the incidence of encephalomalacia, fatty acid status and serum thromboxane levels in chicks.
Topics: Animals; Aspirin; Chickens; Encephalomalacia; Fatty Acids; Thromboxanes; Vitamin E; Vitamin E Deficiency | 1983 |
Changes in the levels of prostaglandins and thromboxane and their roles in the accumulation of exudate in rat carrageenin-induced pleurisy--a profile analysis using gas chromatography-mass spectrometry.
Topics: Animals; Aspirin; Carrageenan; Gas Chromatography-Mass Spectrometry; Imidazoles; Male; Pleurisy; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1982 |
Significance of platelet function and thromboxane B2 levels across the human myocardial vascular bed.
Topics: Arteriosclerosis; Aspirin; Coronary Circulation; Coronary Disease; Coronary Vessels; Dipyridamole; Humans; Platelet Aggregation; Propranolol; Tachycardia; Thromboxane B2; Thromboxanes | 1981 |
Inhibition of prostacyclin and platelet thromboxane A2 after low-dose aspirin.
Topics: Adult; Aspirin; Bleeding Time; Blood Platelets; Epoprostenol; Female; Humans; In Vitro Techniques; Male; Platelet Aggregation; Prostaglandin Antagonists; Thromboxane A2; Thromboxanes; Veins | 1981 |
Humoral heartache -- do platelets have a role?
Topics: Angina Pectoris; Angina Pectoris, Variant; Animals; Aspirin; Blood Platelets; Coronary Circulation; Dogs; Epoprostenol; Humans; Indomethacin; Platelet Aggregation; Thromboxane A2; Thromboxane B2; Thromboxanes | 1981 |
Inhibition of prostacyclin and platelet thromboxane A2 by aspirin.
Topics: Animals; Aspirin; Blood Platelets; Epoprostenol; Humans; Prostaglandin Antagonists; Rats; Thromboxane A2; Thromboxanes | 1981 |
Respiratory movements alter the generation of prostacyclin and thromboxane A2 in isolated rat lungs: the influence of arachidonic acid-pathway inhibitors on the ratio between pulmonary prostacyclin and thromboxane A2.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Aspirin; Epoprostenol; Fatty Acids; Hyperventilation; Indomethacin; Lung; Male; Prostaglandins; Prostaglandins F; Rats; Thromboxane A2; Thromboxanes; Tranylcypromine | 1981 |
[The role of prostacycline, thromboxane A2 and prostaglandins in platelet aggregation (author's transl)].
Topics: Arteriosclerosis; Aspirin; Epoprostenol; Hemostasis; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandins; Thrombosis; Thromboxane A2; Thromboxanes | 1981 |
Leukotriene-C4 induces generation of PGI2 and TXA2 in guinea-pig in vivo.
Topics: Airway Resistance; Animals; Aspirin; Blood Pressure; Epoprostenol; Guinea Pigs; Lung; Lung Compliance; Muscle Contraction; Muscle, Smooth, Vascular; Prostaglandins; SRS-A; Thromboxane A2; Thromboxanes | 1981 |
Prostacyclin and thromboxane A2 formation in response to adrenergic stimulation in humans: a mechanism for local control of vascular response to sympathetic activation?
Topics: Adolescent; Adrenergic Fibers; Adult; Aspirin; Catecholamines; Cold Temperature; Epoprostenol; Female; Humans; Male; Prostaglandins; Thromboxane A2; Thromboxanes; Vascular Resistance | 1981 |
Prostacyclin and thromboxane A2 release in isolated rat lungs.
Topics: Animals; Aspirin; Blood Platelets; Cell Membrane; Epoprostenol; In Vitro Techniques; Lung; Male; Phospholipases A; Phospholipases A2; Prostaglandins; Quinacrine; Rats; Rats, Inbred Strains; Thromboxane A2; Thromboxanes | 1982 |
Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects.
Topics: Adolescent; Adult; Aspirin; Blood Platelets; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Male; Prostaglandins E; Prostaglandins F; Renin; Thromboxane B2; Thromboxanes | 1982 |
Mediation of cardiac ischemia by thromboxanes released from human platelets.
Topics: Aspirin; Blood Platelets; Coronary Circulation; Coronary Disease; Epoprostenol; Fluorescence; Humans; Photography; Prostaglandins E; Thrombin; Thromboxanes | 1982 |
Failure of thromboxane A2 blockade to prevent attacks of vasospastic angina.
Topics: Adult; Aspirin; Coronary Disease; Coronary Vasospasm; Electrocardiography; Humans; Male; Middle Aged; Thromboxane A2; Thromboxane B2; Thromboxanes | 1982 |
The relationship between the production of thromboxane B2 and malondialdehyde by human blood platelets.
Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Humans; In Vitro Techniques; Malonates; Malondialdehyde; Platelet Aggregation; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1980 |
Constitutional thrombocytopathy with subnormal response to thromboxane A2.
Topics: Adolescent; Aspirin; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Female; Humans; Platelet Aggregation; Serotonin; Thromboxane A2; Thromboxanes | 1981 |
Effects of very low versus standard dose acetyl salicylic acid, dipyridamole and sulfinpyrazone on platelet function and thromboxane formation in man.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acids; Aspirin; Blood Platelets; Collagen; Dipyridamole; Dose-Response Relationship, Drug; Female; Humans; Male; Platelet Aggregation; Sulfinpyrazone; Thromboxane B2; Thromboxanes | 1981 |
[Selective anti-aggregation--a new concept for inhibitors of the platelet function (author's transl)].
Topics: Aspirin; Calcium; Depression, Chemical; Fibrinogen; Humans; Platelet Aggregation; Prostaglandins; Sialic Acids; Temperature; Thromboxanes | 1981 |
Heparin inhibits the formation of endoperoxide metabolites in rat platelets: aspirin-like activity.
Topics: Animals; Aspirin; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Heparin; Male; Platelet Aggregation; Prostaglandins E; Rats; Thromboxane A2; Thromboxanes | 1981 |
Platelet aggregation independent of ADP release or prostaglandin synthesis in patients with hermansky-Pudlak syndrome.
Topics: Adenosine Diphosphate; Albinism; Arachidonic Acids; Aspirin; Blood Platelets; Epinephrine; Hemorrhagic Disorders; Humans; Platelet Aggregation; Prostaglandins; Thrombin; Thromboxanes | 1981 |
Aspirin inhibits the early myocardial release of thromboxane B2 and ventricular ectopic activity following acute coronary artery occlusion in dogs.
Topics: Animals; Arrhythmias, Cardiac; Aspirin; Coronary Disease; Dogs; Myocardium; Thromboxane B2; Thromboxanes | 1981 |
Plasma concentrations of thromboxane B2 in patients with hypertension or cerebrovascular disease.
Topics: Adolescent; Adult; Aged; Arteries; Aspirin; Cerebrovascular Disorders; Female; Humans; Hypertension; Jugular Veins; Male; Middle Aged; Thromboxane B2; Thromboxanes; Veins | 1981 |
Platelet aggregation induced by arachidonic acid and thromboxane generation in patients with hypertension or cerebrovascular disease.
Topics: Adolescent; Adult; Aged; Arachidonic Acids; Aspirin; Blood Platelets; Brain Ischemia; Female; Humans; Hypertension; In Vitro Techniques; Male; Middle Aged; Platelet Aggregation; Prostaglandins H; Thromboxane B2; Thromboxanes | 1981 |
Thromboxane synthesis and platelet secretion during cardiopulmonary bypass with bubble oxygenator.
Topics: Aspirin; Blood Platelets; Cardiopulmonary Bypass; Humans; Oxygenators; Platelet Count; Thromboxanes | 1980 |
Changes of prostaglandin and thromboxane levels in pleural fluid of rat carrageenin-induced pleurisy.
Topics: Animals; Aspirin; Butylated Hydroxytoluene; Carrageenan; Disease Models, Animal; Imidazoles; Inflammation; Pleural Effusion; Pleurisy; Prostaglandin Endoperoxides; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Thromboxane B2; Thromboxanes | 1980 |
Determination of specific inhibitors of thromboxane A2 formation.
Topics: Achilles Tendon; Animals; Aorta; Aspirin; Blood Platelets; Clotrimazole; Depression, Chemical; Gastric Mucosa; In Vitro Techniques; Rabbits; Thromboxane A2; Thromboxanes | 1980 |
Radioimmunoassay of serum thromboxane B2: a simple method of assessing pharmacologic effects on platelet function.
Topics: Aspirin; Blood Coagulation; Blood Platelets; Cross Reactions; Diflunisal; Dipyridamole; Humans; Platelet Aggregation; Radioimmunoassay; Thromboxane B2; Thromboxanes | 1980 |
Thromboxane B2 and 6-keto-prostaglandin F1 alpha synthesis during infusion of collagen and arachidonic acid in rabbits: inhibition by aspirin and sulfinpyrazone.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Pressure; Collagen; Dose-Response Relationship, Drug; Female; Platelet Aggregation; Platelet Count; Prostaglandins F; Rabbits; Sulfinpyrazone; Thromboxane B2; Thromboxanes | 1980 |
Bronchoconstriction by histamine and bradykinin in guinea pigs: relationship to thromboxane A2 generation and the effect of aspirin.
Topics: Acetylcholine; Animals; Aspirin; Blood Pressure; Bradykinin; Bronchial Spasm; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Male; Pulse; Rabbits; Thromboxane A2; Thromboxanes | 1980 |
Thromboxane generation in patients with essential hypertension or cerebrovascular disease and effect of oral aspirin.
Topics: Adolescent; Adult; Aged; Arachidonic Acids; Aspirin; Blood Platelets; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle Aged; Prostaglandins H; Thromboxane B2; Thromboxanes | 1980 |
Thromboxane B2 (TxB2) release during IgE anaphylaxis in the rabbit.
Topics: Anaphylaxis; Animals; Aspirin; Basophils; Blood Platelets; Female; Guinea Pigs; Horseradish Peroxidase; Immunoglobulin E; Male; Neutrophils; Platelet Factor 4; Rabbits; Thromboxane B2; Thromboxanes | 1980 |
Impaired thromboxane production by newly formed platelets after aspirin administration to thrombocytopenic rats.
Topics: Animals; Aspirin; Blood Platelets; Male; Malondialdehyde; Platelet Count; Rats; Thrombocytopenia; Thromboxane B2; Thromboxanes; Time Factors | 1980 |
Measurement of thromboxane B2 in human plasma or serum by radioimmunoassay.
Topics: Aspirin; Blood Platelets; Blood Specimen Collection; Female; Humans; Platelet Aggregation; Radioimmunoassay; Temperature; Thromboxane B2; Thromboxanes | 1980 |
Thromboxane biosynthesis and pulmonary function in cystic fibrosis.
Topics: Adolescent; Adult; Aspirin; Blood Platelets; Case-Control Studies; Child; Cystic Fibrosis; Female; Genotype; Humans; Male; Reference Values; Respiratory Function Tests; Thromboxanes | 1995 |
Effects of thromboxane A2 synthase inhibitors (CV-4151 and ozagrel), aspirin, and ticlopidine on the thrombosis caused by endothelial cell injury.
Topics: Animals; Aspirin; Bleeding Time; Endothelium, Vascular; Fatty Acids, Monounsaturated; Femoral Vein; Male; Methacrylates; Platelet Aggregation; Pyridines; Rats; Rats, Sprague-Dawley; Thrombosis; Thromboxane-A Synthase; Thromboxanes; Ticlopidine | 1995 |
Calcitonin gene-related peptide release in endotoxicosis may be mediated by prostaglandins.
Topics: Animals; Aspirin; Blood Glucose; Blood Pressure; Calcitonin Gene-Related Peptide; Cyclooxygenase Inhibitors; Drug Tolerance; Ibuprofen; Imidazoles; Indomethacin; Lactates; Lipopolysaccharides; Male; Prostaglandins; Rats; Rats, Sprague-Dawley; Rats, Wistar; Shock, Septic; Thromboxanes | 1995 |
Antithrombotic effects of KW-3635, a thromboxane A2-receptor antagonist, in guinea pigs.
Topics: Animals; Arterial Occlusive Diseases; Aspirin; Benzimidazoles; Benzoxepins; Blood Coagulation; Blood Platelets; Disease Models, Animal; Erythrocyte Count; Femoral Artery; Guinea Pigs; Lauric Acids; Male; Phenylacetates; Platelet Count; Sulfonamides; Thrombosis; Thromboxane A2; Thromboxanes; Ticlopidine | 1994 |
Severe VA/Q mismatch in perfused lungs evoked by sequential challenge with endotoxin and E. coli hemolysin.
Topics: Animals; Aspirin; Bacterial Proteins; Escherichia coli Proteins; Female; Hemolysin Proteins; In Vitro Techniques; Lipopolysaccharides; Lung; Male; Noble Gases; Phenylacetates; Pulmonary Circulation; Pulmonary Edema; Rabbits; Salmonella; Sulfonamides; Thromboxanes; Ventilation-Perfusion Ratio | 1994 |
Beneficial effects of combined thromboxane synthase inhibition/receptor blockade with CGS 22652 in a canine model of coronary thrombosis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Caprylates; Coronary Circulation; Coronary Thrombosis; Dinoprostone; Dogs; Hemodynamics; Indoles; Male; Myocardial Reperfusion; Phenylacetates; Platelet Activation; Platelet Aggregation Inhibitors; Pyridines; Receptors, Thromboxane; Streptokinase; Sulfonamides; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1993 |
Urinary excretion and origin of 11-dehydro-2,3-dinor-thromboxane B2 in man.
Topics: Adult; Aspirin; Blood Platelets; Humans; Male; Reference Values; Smoking; Thromboxane B2; Thromboxanes | 1993 |
Abnormally high thromboxane biosynthesis in homozygous homocystinuria. Evidence for platelet involvement and probucol-sensitive mechanism.
Topics: Adolescent; Adult; Aspirin; Blood Coagulation; Blood Platelets; Child; Female; Fibrinolysis; Homocystinuria; Homozygote; Humans; Male; Platelet Aggregation; Probucol; Thromboxanes | 1993 |
Staphylococcal alpha-toxin induced ventilation-perfusion mismatch in isolated blood-free perfused rabbit lungs.
Topics: Animals; Aspirin; Bacterial Toxins; Female; Hemolysin Proteins; Lung; Male; Noble Gases; Perfusion; Phenylacetates; Pulmonary Circulation; Pulmonary Edema; Rabbits; Staphylococcus aureus; Sulfonamides; Thromboxanes; Vasoconstriction; Ventilation-Perfusion Ratio | 1993 |
Five-to-seven-day kidney preservation with aspirin and furegrelate.
Topics: Animals; Aspirin; Benzofurans; Creatinine; Dogs; Female; Kidney; Kidney Transplantation; Organ Preservation; Prostaglandin Antagonists; Prostaglandins; Thromboxane-A Synthase; Thromboxanes; Time Factors | 1993 |
Excretion of thromboxane metabolites in healthy women after cessation of smoking.
Topics: Administration, Oral; Adult; Aspirin; Cotinine; Creatinine; Female; Humans; Middle Aged; Smoking; Smoking Cessation; Thromboxane A2; Thromboxanes | 1993 |
Chronic aspirin treatment affects collagen deposition in non-infarcted myocardium during remodeling after coronary artery ligation in the rat.
Topics: Animals; Aspirin; Collagen; Coronary Vessels; Dose-Response Relationship, Drug; Eicosanoids; Endothelium; Epoprostenol; Fibrosis; Heart; Ligation; Male; Myocardial Infarction; Rats; Rats, Wistar; Thromboxanes; Ventricular Function, Left | 1995 |
Cyclooxygenase-1 and -2 of endothelial cells utilize exogenous or endogenous arachidonic acid for transcellular production of thromboxane.
Topics: Arachidonic Acid; Aspirin; Blood Platelets; Cell Communication; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Endothelium, Vascular; Humans; Isoenzymes; Membrane Proteins; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Thrombin; Thromboxanes | 1996 |
Prothrombotic effects of erythrocytes on platelet reactivity. Reduction by aspirin.
Topics: Adult; Aspirin; Blood Platelets; Drug Administration Schedule; Erythrocytes; Female; Humans; Male; Middle Aged; Platelet Activation; Serotonin; Thromboxanes; Time Factors | 1997 |
Aspirin inhibits both lipid peroxides and thromboxane in preeclamptic placentas.
Topics: Aspirin; Blood Platelets; Epoprostenol; Female; Free Radicals; Humans; In Vitro Techniques; Kinetics; Lipid Peroxidation; Lipid Peroxides; Pre-Eclampsia; Pregnancy; Thromboxanes | 1995 |
Enhanced thromboxane biosynthesis in patients with chronic obstructive pulmonary disease. The Chronic Obstructive Bronchitis and Haemostasis Study Group.
Topics: Aged; Aspirin; Blood Platelets; Creatinine; Cyclooxygenase Inhibitors; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Oxygen Inhalation Therapy; Peptide Fragments; Platelet Activation; Prothrombin; Thromboxane B2; Thromboxanes | 1997 |
Postoperative adhesion prevention with low-dose aspirin: effect through the selective inhibition of thromboxane production.
Topics: Abdominal Muscles; Animals; Aspirin; Female; Ovary; Platelet Aggregation Inhibitors; Postoperative Complications; Rabbits; Thrombosis; Thromboxanes; Uterus | 1998 |
Better increase in fibrin gel porosity by low dose than intermediate dose acetylsalicylic acid.
Topics: Adult; Antithrombin III; Aspirin; Dose-Response Relationship, Drug; Female; Fibrin; Fibrinolysis; Fibrinolytic Agents; Gels; Humans; Male; Peptide Hydrolases; Plasminogen Activator Inhibitor 1; Platelet Aggregation Inhibitors; Porosity; Prospective Studies; Thromboxanes | 1998 |
In vivo antithrombotic effects of a nitric oxide-releasing aspirin derivative, NCX-4016.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fibrinolytic Agents; Male; Nitric Oxide; Nitroprusside; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Thromboxanes | 1999 |
Monitoring of the thromboxane A2/prostacyclin ratio in the urine of patients with retinal vascular occlusion through the low-dose-aspirin therapy using the gas chromatography/selected ion monitoring method.
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Aspirin; Dose-Response Relationship, Drug; Epoprostenol; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Pilot Projects; Prostaglandins F; Retinal Artery Occlusion; Retinal Vein Occlusion; Thromboxane A2; Thromboxane B2; Thromboxanes | 1999 |
Gastrointestinal effects of low-dose aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Digestive System; Gastric Mucosa; Humans; Prostaglandins; Research Design; Thromboxanes | 1999 |
COX-2 is not involved in thromboxane biosynthesis by activated human platelets.
Topics: Adult; Aspirin; Blood Platelets; Blotting, Western; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Male; Membrane Proteins; Monocytes; Nitrobenzenes; Platelet Activation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Isoforms; Sulfonamides; Thromboxanes | 1999 |
Thromboxane synthase has the same pattern of expression as platelet specific glycoproteins during human megakaryocyte differentiation.
Topics: Antigens, CD34; Aspirin; Cell Differentiation; Cell Lineage; Cyclooxygenase Inhibitors; DNA-Binding Proteins; Enzyme Induction; Erythroid-Specific DNA-Binding Factors; Gene Expression Regulation; Humans; Leukapheresis; Megakaryocytes; Microscopy, Confocal; Neoplasm Proteins; NF-E2 Transcription Factor; NF-E2 Transcription Factor, p45 Subunit; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Proto-Oncogene Proteins; Receptors, Cytokine; Receptors, Thrombopoietin; Reverse Transcriptase Polymerase Chain Reaction; Thromboxane-A Synthase; Thromboxanes; Transcription Factors; von Willebrand Factor | 2000 |
Habitual smoking causes an abnormality in platelet thromboxane A2 metabolism and results in an altered susceptibility to aspirin effects.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Aspirin; Blood Platelets; Collagen; Epoprostenol; Erythrocytes; Humans; Male; Platelet Aggregation; Smoking; Thromboxane A2; Thromboxanes | 2000 |
Adrenaline potentiates type 2B von Willebrand factor-induced activation of human platelets by enhancing both the formation and action of thromboxanes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Antagonists; Arachidonic Acid; Aspirin; Blood Platelets; Calcium; Drug Synergism; Epinephrine; Humans; Kinetics; Lipoxygenase; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Prostanoic Acids; Serotonin; Sympathomimetics; Thromboxanes; Tyrosine; Vasoconstrictor Agents; von Willebrand Factor; Yohimbine | 2000 |
Aspirin resistance after coronary artery bypass grafting.
Topics: Adult; Aspirin; Blood Platelets; Coronary Artery Bypass; Drug Resistance; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Thromboxanes | 2001 |
Vasorelaxant effects of a nitric oxide-releasing aspirin derivative in normotensive and hypertensive rats.
Topics: Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Blood Pressure; Consciousness; Dose-Response Relationship, Drug; Hypertension; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Phenylephrine; Rats; Rats, Wistar; Renin; Thromboxanes; Vasodilation | 2001 |
Towards a definition of aspirin resistance: a typological approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cardiovascular Diseases; Cerebrovascular Disorders; Drug Resistance; Humans; Platelet Aggregation Inhibitors; Reference Values; Thromboxanes | 2002 |
Why are some individuals resistant to the cardioprotective effects of aspirin? Could it be thromboxane A2?
Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Dose-Response Relationship, Drug; Drug Resistance; Risk Factors; Thromboxane A2; Thromboxanes | 2002 |
Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Canada; Cardiovascular Diseases; Case-Control Studies; Cohort Studies; Comorbidity; Cyclooxygenase Inhibitors; Death, Sudden, Cardiac; Demography; Female; Follow-Up Studies; Humans; Male; Myocardial Infarction; Odds Ratio; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Secondary Prevention; Stroke; Thromboxane B2; Thromboxanes; Vitamin E | 2002 |
Resisting aspirin.
Topics: Aspirin; Cardiovascular Diseases; Drug Resistance; Humans; Thromboxanes | 2002 |
When aspirin doesn't work.
Topics: Aspirin; Drug Resistance; Humans; Thromboxanes; United States | 2002 |
Cyclooxygenase inhibitors and the antiplatelet effects of aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Heart Diseases; Humans; Ibuprofen; Platelet Aggregation Inhibitors; Thromboxanes | 2002 |
Aspirin--first the good news...
Topics: Anticoagulants; Aspirin; Coronary Artery Disease; Humans; Thromboxanes | 2002 |
Effects of the selective inhibition of platelet thromboxane synthesis on the platelet-subendothelium interaction.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Aspirin; Blood Platelets; Chlorobenzenes; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridines; Rabbits; Receptors, Thromboxane; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 2002 |
Aspirin resistance.
Topics: Aspirin; Biomarkers; Cyclooxygenase Inhibitors; Drug Resistance; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Predictive Value of Tests; Risk; Thrombosis; Thromboxane B2; Thromboxanes | 2002 |
Effects of nonsteroidal anti-inflammatory drugs on prostacyclin and thromboxane in the kidney.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Dose-Response Relationship, Drug; Drug Interactions; Epoprostenol; Kidney; Mercuric Chloride; Pyrazoles; Rabbits; Sulfonamides; Thromboxanes | 2003 |
Beneficial effect of aspirin on renal function post-cardiopulmonary bypass.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Cardiopulmonary Bypass; Coronary Artery Bypass; Creatinine; Female; Humans; Kidney; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Renal Insufficiency; Thromboxanes; Urinary Tract Physiological Phenomena | 2003 |
Aspirin.
Topics: Aspirin; Cyclooxygenase 1; Drug Evaluation; Humans; Isoenzymes; Membrane Proteins; Platelet Aggregation; Platelet Function Tests; Prostaglandin-Endoperoxide Synthases; Thromboxanes; Treatment Failure | 2004 |
Aspirin resistance for clinicians.
Topics: Aspirin; Drug Interactions; Drug Resistance; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxanes; Treatment Failure | 2004 |
Differential requirements for calcium and Src family kinases in platelet GPIIb/IIIa activation and thromboxane generation downstream of different G-protein pathways.
Topics: Animals; Aspirin; Blood Platelets; Calcium; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Signal Transduction; src-Family Kinases; Stimulation, Chemical; Thromboxanes | 2005 |
Aspirin resistance: a worry?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Drug Resistance; Fibrinolytic Agents; Humans; Myocardial Infarction; Stroke; Thromboxanes | 2005 |
Is cardiopulmonary bypass a reason for aspirin resistance after coronary artery bypass grafting?
Topics: Aged; Aspirin; Blood Platelets; Cardiopulmonary Bypass; Cells, Cultured; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Postoperative Care; Postoperative Period; Thromboxanes | 2005 |
Dose- and time-dependent antiplatelet effects of aspirin.
Topics: Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cross-Over Studies; Dose-Response Relationship, Drug; Epoprostenol; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2; Thromboxanes; Time Factors | 2006 |
Thromboxane mediates neutrophil superoxide production in pregnancy.
Topics: Arachidonic Acid; Aspirin; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Humans; Indomethacin; Neutrophils; Nitrobenzenes; Phospholipases A; Phospholipases A2; Pregnancy; Sulfonamides; Superoxides; Thromboxane-A Synthase; Thromboxanes | 2006 |
Antioxidant and antiplatelet effects of the alpha-tocopherol-aspirin combination in type 1-like diabetic rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Aspirin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Epoprostenol; Male; Oxidative Stress; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Thromboxanes | 2006 |
Usefulness of whole blood aggregometry and its comparison with thromboxane generation assay in monitoring acetylsalicylic acid effectiveness--a multiparametric study in rats.
Topics: Adenosine Diphosphate; Animals; Aspirin; Biomarkers; Blood Platelets; Cell Aggregation; Collagen; Male; Nephelometry and Turbidimetry; Platelet Aggregation; Rats; Rats, Wistar; Thromboxanes; Time Factors | 2006 |
Cardiovascular aspirin--what is the ideal dose?
Topics: Aspirin; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; Product Surveillance, Postmarketing; Thromboxanes | 2006 |
Heritability, platelet function, and aspirin: a link established but cause unknown.
Topics: Arachidonic Acid; Aspirin; Black or African American; Blood Platelets; Cardiovascular Diseases; Cyclooxygenase 1; Female; Genetic Heterogeneity; Genetic Predisposition to Disease; Genetic Variation; Humans; Male; Membrane Proteins; Phenotype; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Sex Characteristics; Thrombophilia; Thrombosis; Thromboxanes; White People | 2007 |
French maritime pine bark extract Pycnogenol reduces thromboxane generation in blood from diabetic male rats.
Topics: Animals; Aspirin; Blood Glucose; Body Weight; C-Peptide; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Flavonoids; Male; Plant Extracts; Rats; Rats, Wistar; Thromboxane B2; Thromboxanes | 2008 |
[Antiplatelet therapy can unmask an inherited bleeding disorder. Aspirin-like defect of platelets does not protect against atherosclerosis].
Topics: Aged; Aspirin; Blood Platelet Disorders; Coronary Artery Disease; Cyclooxygenase 1; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxanes | 2007 |
Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnancies.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Aspirin; Epoprostenol; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy; Receptors, Thromboxane; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes; Trophoblasts; Vasoconstriction | 2008 |
Pyrazolinone analgesics prevent the antiplatelet effect of aspirin and preserve human platelet thromboxane synthesis.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Blood Platelets; Cells, Cultured; Cyclooxygenase 1; Dipyrone; Drug Antagonism; Humans; Platelet Aggregation; Pyrazolones; Thromboxanes | 2008 |
Elevated cholesterol reduces acetylsalicylic acid-mediated platelet acetylation.
Topics: Acetylation; Aspirin; Blood Platelets; Cholesterol; Humans; Lipid Bilayers; Platelet Aggregation; Thromboxanes | 2007 |
Aspirin is insufficient in inhibition of platelet aggregation and thromboxane formation early after coronary artery bypass surgery.
Topics: Aged; Aspirin; Cardiovascular Diseases; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Platelet Aggregation; Prospective Studies; Thromboxanes | 2009 |
Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Aspirin; Blood; Case-Control Studies; Colony-Forming Units Assay; Endothelial Cells; Female; Humans; Male; Middle Aged; Polycythemia Vera; Stem Cells; Thromboxane A2; Thromboxane B2; Thromboxanes | 2008 |
Pharmacological profile of a novel H(2)S-releasing aspirin.
Topics: 3T3 Cells; Animals; Aorta, Thoracic; Aspirin; Chromatography, High Pressure Liquid; Disulfides; Gastric Mucosa; Glutathione; Heme Oxygenase-1; Hydrogen Sulfide; Isoprostanes; Male; Mice; Myocardium; Promoter Regions, Genetic; Rats; Rats, Wistar; Thromboxanes; Transcriptional Activation; Transfection | 2009 |
Optical platelet aggregation versus thromboxane metabolites in healthy individuals and patients with stable coronary artery disease after low-dose aspirin administration.
Topics: Adult; Aged; Aspirin; Blood Platelets; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Patient Compliance; Platelet Aggregation; Platelet Aggregation Inhibitors; Tablets, Enteric-Coated; Thromboxanes; Time Factors | 2009 |
Letter by cattaneo regarding article, "incomplete inhibition of thromboxane biosynthesis by acetylsalicylic Acid: determinants and effect on cardiovascular risk".
Topics: Aged; Aspirin; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Follow-Up Studies; Humans; Internationality; Male; Middle Aged; Risk Factors; Survival Rate; Thromboxane B2; Thromboxanes | 2009 |
Thromboxane and prostacyclin biosynthesis in heart failure of ischemic origin: effects of disease severity and aspirin treatment.
Topics: Aged; Aged, 80 and over; Aspirin; Epoprostenol; Female; Heart Failure; Humans; Male; Myocardial Ischemia; Severity of Illness Index; Thromboxanes | 2010 |
A comparison of platelet function tests and thromboxane metabolites to evaluate aspirin response in healthy individuals and patients with coronary artery disease.
Topics: Arachidonic Acid; Aspirin; Blood Platelets; Cells, Cultured; Collagen; Coronary Artery Disease; Cyclooxygenase 1; Drug Resistance; Enzyme Inhibitors; Epinephrine; Platelet Activation; Reproducibility of Results; Sensitivity and Specificity; Thromboxanes | 2010 |
The role of weight and enteric coating on aspirin response in cardiovascular patients.
Topics: Aged; Aspirin; Body Weight; Cardiology; Cardiovascular Diseases; Humans; Middle Aged; Patient Compliance; Serum; Tablets, Enteric-Coated; Thromboxanes; Time Factors | 2010 |
Release of sphingosine-1-phosphate from human platelets is dependent on thromboxane formation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aspirin; Blood Platelets; Cells, Cultured; Chromatography, Thin Layer; Humans; Lysophospholipids; Receptors, Thromboxane; Sphingosine; Thrombin; Thromboxanes | 2011 |
Thromboxane metabolite excretion during pregnancy--influence of preeclampsia and aspirin treatment.
Topics: Aspirin; Female; Humans; Pre-Eclampsia; Pregnancy; Thromboxanes | 2011 |
Antagonism of the antithrombotic and anti-atherosclerotic actions of aspirin by rofecoxib in the cholesterol-fed rabbit.
Topics: Animal Feed; Animals; Aorta; Aspirin; Atherosclerosis; Cholesterol; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Drug Antagonism; Epoprostenol; Female; Fibrinolytic Agents; Immunohistochemistry; Lactones; Male; Platelet Aggregation Inhibitors; Rabbits; Sulfones; Thrombosis; Thromboxanes | 2011 |
Aspirin resistance and platelet turnover: a 25-year old issue.
Topics: Animals; Aspirin; Blood Platelets; Diabetic Angiopathies; Disease Models, Animal; Drug Resistance; Humans; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Thromboxanes | 2011 |
Aspirin has little additional anti-platelet effect in healthy volunteers receiving prasugrel.
Topics: Adolescent; Adult; Aspirin; Humans; Male; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Thromboxanes | 2011 |
Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane.
Topics: Adult; Aged; Aged, 80 and over; Aldehyde Reductase; Aspirin; Blood Glucose; Case-Control Studies; Collagen; Diabetes Mellitus; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Male; Middle Aged; Mitogen-Activated Protein Kinase 14; Models, Biological; Oxidative Stress; Phospholipase C gamma; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Reactive Oxygen Species; Signal Transduction; Thromboxanes; Venous Thrombosis | 2011 |
Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury.
Topics: Acute Lung Injury; Animals; Antibodies, Monoclonal; Aspirin; Blood Platelets; Cell Aggregation; Cells, Cultured; Deoxyribonuclease I; Histones; Human Umbilical Vein Endothelial Cells; Humans; Lipopolysaccharides; Lung; Mice; Neutrophils; Permeability; Peroxidase; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxanes; Transfusion Reaction | 2012 |
Laboratory effect on platelet activity within 24 h of the first 300-mg oral dose of aspirin given in hospital during the acute phase of ischemic cerebral events.
Topics: Acute Disease; Administration, Oral; Aged; Aspirin; Blood Platelets; Brain Ischemia; Female; Humans; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Thromboxanes; Time Factors | 2012 |
High glucose inhibits the aspirin-induced activation of the nitric oxide/cGMP/cGMP-dependent protein kinase pathway and does not affect the aspirin-induced inhibition of thromboxane synthesis in human platelets.
Topics: Adult; Amifostine; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cell Adhesion Molecules; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Drug Resistance; Female; Humans; Hyperglycemia; Lysine; Male; Microfilament Proteins; Nitric Oxide; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Protein Processing, Post-Translational; Second Messenger Systems; Thromboxanes; Vasodilator Agents; Young Adult | 2012 |
Human thromboxane A2 receptor genetic variants: in silico, in vitro and "in platelet" analysis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aspirin; Binding Sites; Binding, Competitive; Blood Platelets; Cell Line; Cyclooxygenase Inhibitors; Genetic Association Studies; Humans; Models, Molecular; Molecular Sequence Data; Phosphoproteins; Platelet Activation; Polymorphism, Single Nucleotide; Protein Structure, Secondary; Protein Structure, Tertiary; Proteome; Receptors, Thromboxane A2, Prostaglandin H2; Signal Transduction; Thromboxanes | 2013 |
Dipyrone (metamizole) can nullify the antiplatelet effect of aspirin in patients with coronary artery disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Artery Disease; Dipyrone; Drug Interactions; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxanes | 2013 |
The effects of an inhibitor of diglyceride lipase on collagen-induced platelet activation.
Topics: Arachidonic Acid; Aspirin; Blotting, Western; Collagen; Enzyme Inhibitors; Humans; Isoleucine; Lactones; Lipoprotein Lipase; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activation; Platelet Aggregation; Thromboxanes | 2013 |
[Influence of new N,N'-substituted piperazines on thrombin-induced platelet activation].
Topics: Adult; Aspirin; Blood Platelets; Calcium; Female; Gene Expression; Humans; Inositol Phosphates; Male; P-Selectin; Piperazines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Signal Transduction; Thrombin; Thromboxanes | 2014 |
Aspirin Resistance in Single-Ventricle Physiology: Aspirin Prophylaxis Is Not Adequate to Inhibit Platelets in the Immediate Postoperative Period.
Topics: Aspirin; Blalock-Taussig Procedure; Dose-Response Relationship, Drug; Drug Resistance; Female; Follow-Up Studies; Humans; Hypoplastic Left Heart Syndrome; Incidence; Infant; Infant, Newborn; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Texas; Thrombelastography; Thrombosis; Thromboxanes | 2015 |
Drug-Free Platelets Can Act as Seeds for Aggregate Formation During Antiplatelet Therapy.
Topics: Aspirin; Blood Platelets; Drug Therapy, Combination; Flow Cytometry; Humans; In Vitro Techniques; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Sensitivity and Specificity; Thromboxanes | 2015 |
Antiplatelet effects of aspirin in chronic kidney disease patients.
Topics: Aged; Aged, 80 and over; Arachidonic Acid; Aspirin; Blood Platelets; Cardiovascular Diseases; Cross-Sectional Studies; Drug Resistance; Female; Glomerular Filtration Rate; Humans; Kidney; Linear Models; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Renal Insufficiency, Chronic; Risk Factors; Severity of Illness Index; Thromboxanes | 2016 |
Role of thromboxane-dependent platelet activation in venous thrombosis: Aspirin effects in mouse model.
Topics: Animals; Aspirin; Blood Platelets; Cell-Derived Microparticles; Disease Models, Animal; Male; Mice; Neutrophils; Platelet Activation; Platelet Aggregation Inhibitors; Thromboplastin; Thromboxanes; Vena Cava, Inferior; Venous Thrombosis | 2016 |
Antitumor and Antiangiogenic Effects of Aspirin-PC in Ovarian Cancer.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Biomarkers; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Hypoxia; Mice; Neovascularization, Pathologic; Ovarian Neoplasms; Phosphatidylcholines; Thromboxanes; Xenograft Model Antitumor Assays | 2016 |
The time between venepuncture and blood incubation is critical for serum thromboxane B2 synthesis.
Topics: Aspirin; Thromboxane B2; Thromboxanes | 2017 |
Thromboxane Formation Assay to Identify High On-Treatment Platelet Reactivity to Aspirin.
Topics: Aspirin; Blood Platelets; Humans; Platelet Aggregation Inhibitors; Thromboxanes | 2017 |
Effects of high- and low-dose aspirin on adaptive immunity and hypertension in the stroke-prone spontaneously hypertensive rat.
Topics: Adaptive Immunity; Angiotensin II; Animals; Aspirin; Biomarkers; Blood Pressure; Blood Vessels; Cardiomegaly; Cyclooxygenase 1; Cyclooxygenase 2; Cytokines; Disease Susceptibility; Dose-Response Relationship, Drug; Epoprostenol; Hypertension; Kidney; Mice; Rats; Rats, Inbred SHR; Real-Time Polymerase Chain Reaction; RNA, Messenger; Stroke; Systole; T-Lymphocytes; Thromboxanes | 2019 |
Aspirin In The Prevention Of Pre-Eclampsia: Where Are We Now?
Topics: Aspirin; Blood Platelets; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Endothelium; Epoprostenol; Female; Humans; Pre-Eclampsia; Pregnancy; Prostaglandin-Endoperoxide Synthases; Risk; Thromboxanes | 2018 |
The emergent phenomenon of aspirin resistance: insights from genetic association studies.
Topics: Aspirin; Drug Resistance; Genetic Association Studies; Genotype; Humans; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Prostaglandin-Endoperoxide Synthases; Thromboxanes | 2020 |
Rivaroxaban reduces thromboxane induced platelet aggregation - the forgotten compass arm?
Topics: Aspirin; Chronic Disease; Drug Therapy, Combination; Heart Diseases; Humans; Platelet Aggregation; Platelet Function Tests; Rivaroxaban; Thromboxanes | 2021 |
Comparative study on the effect of aspirin, TP receptor antagonist and TxA
Topics: Arachidonic Acid; Aspirin; Benzofurans; Carbazoles; Enzyme Inhibitors; Female; Humans; Male; Mammary Arteries; Muscle, Smooth, Vascular; Phenylephrine; Receptors, Prostaglandin; Receptors, Thromboxane; Saphenous Vein; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes; Vasoconstriction | 2021 |
Association of Platelet Thromboxane Inhibition by Low-Dose Aspirin With Platelet Count and Cytoreductive Therapy in Essential Thrombocythemia.
Topics: Aspirin; Cytoreduction Surgical Procedures; Humans; Platelet Aggregation Inhibitors; Platelet Count; Thrombocythemia, Essential; Thromboxanes | 2022 |
Less Thromboxane, Longer Life.
Topics: Aspirin; Blood Platelets; Humans; Thromboxane B2; Thromboxanes | 2022 |
Effectiveness of aspirin vs. clopidogrel in dogs with immune mediated haemolytic anaemia evaluated by serial thromboelastography and platelet mapping.
Topics: Adenosine Diphosphate; Anemia, Hemolytic, Autoimmune; Animals; Aspirin; Blood Platelets; Clopidogrel; Dog Diseases; Dogs; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Thrombelastography; Thromboxanes | 2022 |
High-Intensity Exercise Training Improves Basal Platelet Prostacyclin Sensitivity and Potentiates the Response to Dual Anti-Platelet Therapy in Postmenopausal Women.
Topics: Adenosine; Adenosine Diphosphate; Aspirin; Cyclooxygenase 1; Diphosphates; Dual Anti-Platelet Therapy; Epoprostenol; Estrogens; Exercise; Female; Humans; Nitric Oxide; Peptides; Platelet Aggregation Inhibitors; Postmenopause; Receptors, Epoprostenol; Receptors, Thromboxane; Thrombin; Thrombosis; Thromboxanes | 2022 |
Aspirin Inhibits the Inflammatory Response of Protease-Activated Receptor 1 in Pregnancy Neutrophils: Implications for Treating Women with Preeclampsia.
Topics: Aspirin; Bicyclic Monoterpenes; Cyclooxygenase 2; Female; Humans; Inflammation; Neutrophils; Peptide Hydrolases; Pre-Eclampsia; Pregnancy; Receptor, PAR-1; Thromboxanes | 2022 |
Drug-Drug Interaction between Antiplatelet Therapy and Lipid-Lowering Agents (Statins and PCSK9 Inhibitors).
Topics: Aspirin; Cholesterol, LDL; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; PCSK9 Inhibitors; Platelet Aggregation Inhibitors; Proprotein Convertase 9; Thromboxanes | 2023 |
Trial of thromboxane receptor inhibition with ifetroban: TP receptors regulate eicosanoid homeostasis in aspirin-exacerbated respiratory disease.
Topics: Animals; Aspirin; Asthma, Aspirin-Induced; Dinoprostone; Eicosanoids; Homeostasis; Humans; Leukotriene E4; Mice; Prostaglandins; Receptors, Thromboxane; Sinusitis; Thromboxanes | 2023 |