aspirin and sulindac

aspirin has been researched along with sulindac in 119 studies

Research

Studies (119)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (31.09)	18.7374
1990's	22 (18.49)	18.2507
2000's	28 (23.53)	29.6817
2010's	29 (24.37)	24.3611
2020's	3 (2.52)	2.80

Authors

Authors	Studies
Hannah, J; Holtz, WJ; Houser, RA; Jones, H; Kelly, KW; Matzuk, AR; Ruyle, WV; Sarett, LH; Shen, TY; Witzel, BE	1
Duffy, EM; Jorgensen, WL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Barreiro, EJ; Fraga, CA; Lima, LM; Romeiro, NC; Sant'Anna, CM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Kumar, M; Sinha, VR; Thareja, S	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, T; Guan, J; Liao, J; Luo, J; Qin, X; Talley, JJ; Tortorella, MD; Tu, Z; Zhang, Y	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Onadeko, BO; Oyemade, GA	1
Evens, RP	1
Pemberton, RE; Strand, LJ	1
Gupta, SK; Joshi, S	1
Ericksen, N; Furst, DE; Hash, L; Herman, RA; Koehnke, R; Porras, A; Riggs, CE; Veng-Pedersen, P	1
Barrow, SE; Cockcroft, JR; Minuz, P; Ritter, JM	1
Babins, E; Hart, DA; Mannerfeldt, J	1
Epstein, C; Kinberg-Calhoun, J; Mullane, JF; Sanda, M; Shand, DG	1
Boss, AH; Catella, F; Ciabattoni, G; Daffonchio, L; Daugherty, J; Dray, F; FitzGerald, GA; Patrono, C	1
Catella, F; Ciabattoni, G; Filabozzi, P; Forni, L; Patrignani, P; Patrono, C; Pierucci, A; Pugliese, F; Segni, M; Simonetti, BM	1
Ciabattoni, G; Cominelli, F; Gentilini, P; La Villa, G; Laffi, G; Mannelli, M; Patrignani, P; Pinzani, M	1
Benigni, A; Bertani, T; Carminati, C; Cutillo, F; Morelli, C; Remuzzi, G; Rocchi, G; Verroust, P	1
Anderson, WP; Bobik, A	1
Cheng, CP; Choy, YM; Fung, KP; Lee, CY; Loh, SC; Luey, LU	1
Penning, TM; Smithgall, TE	1
Facoory, B; Faed, JM; McQueen, EG	1
Altman, R	1
Bhettay, E	1
Davies, RO; Graham, DY; Holmes, GI; Smith, JL	1
Catella, F; Ciabattoni, G; Davì, G; Filabozzi, P; Forni, L; Patrignani, P; Patrono, C; Pugliese, F	1
Rainsford, KD	1
Glavin, GB; Sitar, DS	1
Fanelli, V; Paolinelli, E; Piergiacomi, G	1
Macauley, D	1
Ciabattoni, G; Cinotti, GA; Filabozzi, P; Patrignani, P; Patrono, C; Pierucci, A; Pinca, E; Pugliese, F; Satta, MA; Simonetti, BM; van Dorne, D	1
Bune, AJ; Chalmers, JP; Graham, JR; West, MJ; Wing, LM	1
Altman, RD	1
Ward, JR	1
Patrono, C	1
Guobis, G; Iushenaite, Ia	1
Albert, KS; Gernaat, CM	1
Brandt, KD; Palmoski, MJ	1
Bhalla, AK; Simon, LS	1
Hunt, JN; Jiang, CL; Smith, JL	1
Isenman, DE; Minta, JO; Smythe, HA; Urowitz, MB	1
Obel, AO	1
Djaldetti, M; Elian, I; Globerson, A; Klein, B; Notti, I; Tiomny, A	1
Crabtree, RE; Johnson, DW; Ridolfo, AS; Rockhold, FW	1
Huskisson, EC	1
Brown, MM; Markus, HS; Vallance, P	1
Luk, GD	1
Detrisac, CJ; Hawk, ET; Kelloff, GJ; McCormick, DL; Rao, KV; Steele, VE	1
DuBois, RN; Giardiello, FM; Smalley, WE	1
Fowler, CJ; Stenström, A; Tiger, G	1
Jansen, JB; Peters, WH; Tiemessen, DM; van Lieshout, EM	1
DuBois, RN; Smalley, WE	1
Benamouzig, R; Chaussade, S; Couturier, D; Little, J; Munoz, N; Rautureau, J	1
Castonguay, A; Duperron, C	1
Castonguay, A; Rioux, N	1
DuBois, RN; Smalley, W; Williams, CS	1
Peters, WH; Roelofs, HM; Tiemessen, DM; Van Lieshout, EM	1
Bocker, T; Brockhoff, G; Dietmaier, W; Fishel, R; Hofstädter, F; Rüschoff, J; Wallinger, S	1
Boone, WT	1
Benamouzig, R	1
Giuliano, F; Warner, TD	1
Fukushima, H; Hinoda, Y; Imai, K; Itoh, F; Yamamoto, H	1
DeLong, MJ; Patten, EJ	1
Chiu, CH; McEntee, MF; Whelan, J	1
Caspari, R; Jungck, M; Lamberti, C; Sauerbruch, T; Schmidt-Wolf, I	1
Patrignani, P	1
Gaynor, RB; Guo, J; Kwak, YT; Shen, J	1
Badimon, JJ; Cordon-Cardo, C; Dansky, H; Fallon, JT; Fisher, EA; Reis, ED; Roque, M; Shiff, SJ	1
Masferrer, JL; Needleman, P	1
Akashi, H; Han, HJ; Iizaka, M; Nakamura, Y	1
Borgo, S; Castillo, E; Hasan, I; Rigas, B; Traganos, F; Williams, JL	1
Amberger, A; Dietl, P; Margreiter, R; Ofner, D; Weiss, H; Widschwendter, M	1
Jiang, MC; Lee, PH; Liao, CF	1
Dedhar, S; Dupuis, B; Gallinger, S; Gray, V; Malik, S; Marotta, A; Owen, D; Salh, B; Sanghera, J; Tan, C	1
Benamouzig, R; Chaussade, S	1
Akashi, H; Furukawa, Y; Iizaka, M; Nakamura, Y; Ogawa, M; Tsunoda, T	1
Gao, X; Li, M; Song, S; Sun, F; Sun, H; Sun, S; Zhang, W	1
Jeon, GA; Kim, KY; Nam, MJ; Seol, JY	1
Bauer, WM; Burke, CA; Lashner, B	1
Brooks, G; Crabbe, MJ; Harper, JV; Shattock, MJ; Wang, Y; Yu, XM	1
Brooks, G; Harper, J; Li, YQ; Wang, YQ; Wu, XS; Yuan, WZ; Zhu, CB	1
Dargan, PI; Jones, AL; O'Connor, N	1
Raskov, HH	1
Xiao, H; Yang, CS	1
Chen, J; Rigas, B; Sun, Y	1
Marshall, JR	1
de Jong, S; de Vries, EG; Heijink, DM; Hollema, H; Jalving, M; Kleibeuker, JH; Koornstra, JJ; Koster, R; Oosterhuis, D; Sloots, IA	1
Huang, L; Johnson, F; Komninou, D; Mackenzie, G; Ouyang, N; Rigas, B; Sun, Y; Xie, G	1
Gołab, J; Jakubowska-Mućka, A; Lasek, W; Sieńko, J; Switaj, T	1
Chang, CH; Chen, YC; Fan, SC; Huang, CH; Liu, C; Tsai, AL; Wu, CC	1
Huang, L; Komninou, D; Mackenzie, GG; Ouyang, N; Rigas, B; Sun, Y; Vrankova, K; Xie, G	1
Cheng, KW; Constantinides, PP; Rigas, B; Wong, CC; Xie, G; Zhou, D; Zhu, CH	1
Boring, D; Chattopadhyay, M; Dastagirzada, YM; Kashfi, K; Kodela, R; Nath, N; Velázquez-Martínez, CA	1
Manzano, A; Pérez-Segura, P	1
Chen, HX; Hu, LN; Li, JK; Peng, X; Xie, LX	1
Fischer, SM; Lubet, RA; Mikulec, CD; Rundhaug, JE; Simper, MS	1
Cheng, KW; Huang, L; Mattheolabakis, G; Ouyang, N; Papayannis, I; Rigas, B; Wong, CC; Xie, G	1
Barnholtz-Sloan, JS; Chen, Y; Dawson, DM; Fink, SP; Kopelovich, L; Kresak, A; Lawrence, EG; Markowitz, SD; Willis, JE; Yang, P; Zhang, Y	1
Eglinton, T; Eteuati, J; Frizelle, F; Hollington, P; Keenan, J; Wakeman, C	1
Lynch, PM	1
Ahnen, DJ; Lynch, PM; Ricciardiello, L	1
Burke, CA; Chick, RC; Cindass, JL; Clifton, GT; Ensley, DC; Hale, DF; Hickerson, AT; Kemp Bohan, PM; Mankaney, G; Peoples, GE; Sohn, V; Vreeland, TJ	1
Chang, HY; Chen, HY; Ekanem, TI; Huang, TC; Lee, KH; Lin, YH; Tan, WQ; Tsai, WL	1
Chang, WC; Huang, NK; Huang, WC; Lin, YC; Wang, YS	1

Reviews

26 review(s) available for aspirin and sulindac

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drugs, prostaglandins, and renal function. Advances in prostaglandin, thromboxane, and leukotriene research, 1985, Volume: 13 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Aspirin; Cyclooxygenase Inhibitors; Diuretics; Humans; Kidney; Pharmaceutical Preparations; Prostaglandins; Sulfinpyrazone; Sulindac; Thromboxane-A Synthase	1985
Clinical pharmacology of platelet cyclooxygenase inhibition. Circulation, 1985, Volume: 72, Issue:6 Topics: Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Epoprostenol; Fibrinolytic Agents; Humans; Sulfinpyrazone; Sulindac; Thromboxane B2; Time Factors	1985
Review of ibuprofen for osteoarthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin	1984
Update on ibuprofen for rheumatoid arthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin	1984
Tissue-selective inhibition of prostaglandin and thromboxane synthesis in man: investigative and therapeutic implications. Clinical physiology (Oxford, England), 1984, Volume: 4, Issue:6 Topics: Antithrombins; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Gastric Mucosa; Humans; Kidney; Kinetics; Oxidoreductases; Prostaglandin Antagonists; Salicylates; Sulindac; Thromboxane-A Synthase	1984
[Pharmacodynamics and adverse effects of modern nonsteroid anti-inflammatory agents]. Terapevticheskii arkhiv, 1981, Volume: 53, Issue:7 Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Eruptions; Drug Interactions; Female; Gastrointestinal Diseases; Headache; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; Sulindac	1981
Practical therapeutics: the newer nonsteroidal anti-inflammatory drugs. East African medical journal, 1982, Volume: 59, Issue:6 Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Diclofenac; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Phenylbutyrates; Piroxicam; Propionates; Sulindac; Thiazines	1982
Prevention of gastrointestinal cancer--the potential role of NSAIDs in colorectal cancer. Schweizerische medizinische Wochenschrift, 1996, May-11, Volume: 126, Issue:19 Topics: Adenomatous Polyposis Coli; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Clinical Trials as Topic; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Epidemiologic Methods; Gastrointestinal Neoplasms; Humans; Sulindac	1996
Nonsteroidal anti-inflammatory drugs, eicosanoids, and colorectal cancer prevention. Gastroenterology clinics of North America, 1996, Volume: 25, Issue:4 Topics: Adenomatous Polyposis Coli; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Case-Control Studies; Clinical Trials as Topic; Colorectal Neoplasms; Disease Models, Animal; Eicosanoids; Humans; Incidence; Mice; Prospective Studies; Rats; Retrospective Studies; Sulindac	1996
Colorectal cancer and nonsteroidal anti-inflammatory drugs. Advances in pharmacology (San Diego, Calif.), 1997, Volume: 39 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Humans; Incidence; Prospective Studies; Retrospective Studies; Sulindac; United States	1997
[Aspirin, non-steroidal anti-inflammatory agents and colonic carcinogenesis]. Gastroenterologie clinique et biologique, 1997, Volume: 21, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Neoplasms; Colorectal Neoplasms; Humans; Sulindac	1997
Aspirin use and potential mechanisms for colorectal cancer prevention. The Journal of clinical investigation, 1997, Sep-15, Volume: 100, Issue:6 Topics: Adenocarcinoma; Adenomatous Polyps; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Male; Membrane Proteins; Mice; Prostaglandin-Endoperoxide Synthases; Randomized Controlled Trials as Topic; Sulindac	1997
Nonsteroidal anti-inflammatory drugs, COX-2 and colorectal cancer. Toxicology letters, 2000, Mar-15, Volume: 112-113 Topics: Adenomatous Polyposis Coli; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Humans; Sulindac	2000
Anti-inflammatories for cardiovascular disease. Proceedings of the National Academy of Sciences of the United States of America, 2000, Nov-07, Volume: 97, Issue:23 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Aspirin; Cardiovascular Diseases; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Membrane Proteins; Mice; Prostaglandin-Endoperoxide Synthases; Sulindac	2000
[Chemoprevention of colorectal cancer]. Presse medicale (Paris, France : 1983), 2002, Jan-26, Volume: 31, Issue:3 Topics: Adenomatous Polyposis Coli; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arthritis, Rheumatoid; Aspirin; Calcium, Dietary; Case-Control Studies; Cohort Studies; Colorectal Neoplasms; Controlled Clinical Trials as Topic; Cyclooxygenase Inhibitors; Dietary Supplements; Eflornithine; Enzyme Inhibitors; Female; Folic Acid; Hormone Replacement Therapy; Humans; Male; Mice; Mice, Knockout; Middle Aged; Risk Factors; Sulindac; Time Factors; Vitamins	2002
Chemoprevention of colorectal cancer: slow, steady progress. Cleveland Clinic journal of medicine, 2003, Volume: 70, Issue:4 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Celecoxib; Colorectal Neoplasms; Folic Acid; Humans; Pyrazoles; Sulfonamides; Sulindac	2003
Hepatocellular damage from non-steroidal anti-inflammatory drugs. QJM : monthly journal of the Association of Physicians, 2003, Volume: 96, Issue:11 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induced Liver Injury; Diclofenac; Disease Susceptibility; Drug Hypersensitivity; Female; Humans; Liver Diseases; Liver Failure, Acute; Middle Aged; Mitochondria, Liver; Risk Factors; Sulindac	2003
[Non-steroidal anti-inflammatory agents and prevention of colorectal adenomas and carcinomas]. Ugeskrift for laeger, 2006, Jan-23, Volume: 168, Issue:4 Topics: Adenoma; Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma; Celecoxib; Colorectal Neoplasms; Evidence-Based Medicine; Humans; Meta-Analysis as Topic; Pyrazoles; Sulfonamides; Sulindac	2006
Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention. International journal of cancer, 2008, Sep-01, Volume: 123, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Atorvastatin; Celecoxib; Colorectal Neoplasms; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Evidence-Based Medicine; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Meta-Analysis as Topic; Neoplasms; Pravastatin; Pyrazoles; Pyridines; Pyrroles; Randomized Controlled Trials as Topic; Simvastatin; Sulfonamides; Sulindac	2008
Nutrition and colon cancer prevention. Current opinion in clinical nutrition and metabolic care, 2009, Volume: 12, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Colonic Neoplasms; Diet; Dietary Fiber; Eflornithine; Epidemiologic Studies; Humans; Nutritional Physiological Phenomena; Primary Prevention; Risk Factors; Smoking; Sulindac	2009
Colorectal cancer chemoprevention: is this the future of colorectal cancer prevention? TheScientificWorldJournal, 2012, Volume: 2012 Topics: Adenoma; Adenomatous Polyposis Coli; Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Humans; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Sulindac	2012
Chemoprevention of colorectal neoplasia. ANZ journal of surgery, 2017, Volume: 87, Issue:12 Topics: Adenomatous Polyposis Coli; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiotoxicity; Chemoprevention; Clinical Trials as Topic; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Cyclooxygenase 2 Inhibitors; Disease Progression; Humans; Incidence; Meta-Analysis as Topic; Middle Aged; Sulindac; Young Adult	2017
Chemoprevention of familial adenomatous polyposis. Familial cancer, 2016, Volume: 15, Issue:3 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Celecoxib; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colectomy; Cyclooxygenase 2 Inhibitors; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Eflornithine; Evidence-Based Medicine; Humans; Prophylactic Surgical Procedures; Remission Induction; Sulindac	2016
Chemoprevention of hereditary colon cancers: time for new strategies. Nature reviews. Gastroenterology & hepatology, 2016, Volume: 13, Issue:6 Topics: Adenomatous Polyposis Coli; Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Chemoprevention; Clinical Trials as Topic; Colonic Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Curcumin; Cyclooxygenase 2 Inhibitors; Drug Discovery; Fatty Acids, Omega-3; Humans; Mice; Randomized Controlled Trials as Topic; Rats; Sulindac	2016
Chemoprevention in familial adenomatous polyposis: past, present and future. Familial cancer, 2021, Volume: 20, Issue:1 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Ascorbic Acid; Aspirin; Capsules; Celecoxib; Chemoprevention; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Eflornithine; Erlotinib Hydrochloride; Fatty Acids, Nonesterified; Genes, APC; Humans; Sirolimus; Sulindac; TOR Serine-Threonine Kinases; Vitamins	2021

Trials

16 trial(s) available for aspirin and sulindac

Article	Year
A controlled clinical study comparing sulindac with ibuprofen and aspirin in the treatment of musculo-skeletal diseases. The Journal of international medical research, 1979, Volume: 7, Issue:6 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Back Pain; Clinical Trials as Topic; Female; Humans; Ibuprofen; Indenes; Lumbosacral Region; Male; Middle Aged; Osteoarthritis; Random Allocation; Sulindac; Tenosynovitis	1979
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents. Digestive diseases and sciences, 1979, Volume: 24, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Fenoprofen; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Ibuprofen; Ketoprofen; Naproxen; Phenylbutazone; Registries; Sulindac; Tolmetin	1979
Effects of non-steroidal anti-inflammatory drugs on prostacyclin and thromboxane biosynthesis in patients with mild essential hypertension. British journal of clinical pharmacology, 1990, Volume: 30, Issue:4 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Chromatography, Affinity; Epoprostenol; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypertension; Ibuprofen; Kidney; Male; Middle Aged; Sulindac; Thromboxanes	1990
The effect of etodolac administration on renal function in patients with arthritis. Journal of clinical pharmacology, 1986, Volume: 26, Issue:4 Topics: Acetates; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Double-Blind Method; Etodolac; Humans; Ibuprofen; Kidney Function Tests; Middle Aged; Osteoarthritis; Sulindac	1986
Non-steroidal anti-inflammatory drugs and platelet function. The New Zealand medical journal, 1986, May-28, Volume: 99, Issue:802 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Diflunisal; Female; Humans; Male; Malondialdehyde; Middle Aged; Naproxen; Piroxicam; Sulindac; Time Factors	1986
International experiences with diclofenac in osteoarthritis. The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B Topics: Aspirin; Clinical Trials as Topic; Diclofenac; Diflunisal; Double-Blind Method; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Naproxen; Osteoarthritis; Random Allocation; Sulindac	1986
Double-blind study of sulindac and aspirin in juvenile chronic arthritis. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1986, Dec-06, Volume: 70, Issue:12 Topics: Adolescent; Adult; Arthritis, Juvenile; Aspirin; Child; Child, Preschool; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Indenes; Male; Random Allocation; Sulindac	1986
Nonsteroidal anti-inflammatory effect of sulindac sulfoxide and sulfide on gastric mucosa. Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:1 Topics: Administration, Oral; Adult; Aspirin; Double-Blind Method; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Indenes; Male; Random Allocation; Sulindac	1985
Effects of indomethacin, sulindac, naproxen, aspirin, and paracetamol in treated hypertensive patients. Clinical and experimental hypertension. Part A, Theory and practice, 1984, Volume: 6, Issue:6 Topics: Acetaminophen; Aldosterone; Aspirin; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Humans; Hypertension; Indenes; Indomethacin; Naproxen; Placebos; Random Allocation; Renin; Sodium; Sulindac; Time Factors	1984
Review of ibuprofen for osteoarthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin	1984
Update on ibuprofen for rheumatoid arthritis. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin	1984
[Pharmacodynamics and adverse effects of modern nonsteroid anti-inflammatory agents]. Terapevticheskii arkhiv, 1981, Volume: 53, Issue:7 Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Eruptions; Drug Interactions; Female; Gastrointestinal Diseases; Headache; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; Sulindac	1981
Gastric bleeding and gastric secretion with sulindac and naproxen. Digestive diseases and sciences, 1983, Volume: 28, Issue:2 Topics: Aspirin; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Indenes; Intestinal Absorption; Male; Naproxen; Placebos; Sulindac	1983
Effect of antiinflammatory drugs on the phagocytic activity of peripheral blood monocytes. Prostaglandins, leukotrienes, and medicine, 1982, Volume: 9, Issue:3 Topics: Adult; Anti-Inflammatory Agents; Aspirin; Female; Flufenamic Acid; Humans; Indomethacin; Listeria monocytogenes; Male; Middle Aged; Monocytes; Phagocytosis; Phenylbutazone; Sulindac	1982
Gastrointestinal microbleeding: comparisons between benoxaprofen and other nonsteroidal antiinflammatory agents. The Journal of rheumatology. Supplement, 1980, Volume: 6 Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzoxazoles; Clinical Trials as Topic; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Indomethacin; Melena; Naproxen; Propionates; Prostaglandins; Sulindac; Time Factors	1980
[Experience with sulindac in rheumatoid arthritis and osteoarthritis]. Reumatizam, 1980, Volume: 27, Issue:2 Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Humans; Indenes; Osteoarthritis; Placebos; Sulindac	1980

Other Studies

80 other study(ies) available for aspirin and sulindac

Article	Year
Novel analgesic-antiinflammatory salicylates. Journal of medicinal chemistry, 1978, Volume: 21, Issue:11 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Dogs; Rats; Salicylates; Structure-Activity Relationship	1978
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
NSAIDs revisited: putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARgamma). European journal of medicinal chemistry, 2008, Volume: 43, Issue:9 Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalytic Domain; Computational Biology; Drug Design; Ligands; Models, Molecular; PPAR gamma; Protein Conformation; Software	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Synthesis and Evaluation of Novel Erlotinib-NSAID Conjugates as More Comprehensive Anticancer Agents. ACS medicinal chemistry letters, 2015, Oct-08, Volume: 6, Issue:10 Topics:	2015
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Antirheumatic agents. The Journal of the Maine Medical Association, 1979, Volume: 70, Issue:4 Topics: Adrenal Cortex Hormones; Antimalarials; Aspirin; Azathioprine; Chloroquine; Cyclophosphamide; Gold; Humans; Hydroxychloroquine; Immunosuppressive Agents; Indomethacin; Penicillamine; Phenylbutazone; Phenylpropionates; Rheumatic Diseases; Salicylates; Sulindac; Tolmetin	1979
Relationship between aldose reductase inhibiting activity and anti-cataract action of various non-steroidal anti-inflammatory drugs. Developments in ophthalmology, 1991, Volume: 21 Topics: Aldehyde Reductase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cataract; Flurbiprofen; Galactose; Lens, Crystalline; Naproxen; Ophthalmic Solutions; Piroxicam; Rats; Sulindac	1991
Effect of aspirin and sulindac on methotrexate clearance. Journal of pharmaceutical sciences, 1990, Volume: 79, Issue:9 Topics: Arthritis, Rheumatoid; Aspirin; Drug Interactions; Female; Humans; Male; Methotrexate; Sulindac	1990
Treatment of mice with indomethacin leads to the appearance of a 125,000 dalton plasma protein with the characteristics of an acute phase reactant. Journal of clinical & laboratory immunology, 1987, Volume: 23, Issue:2 Topics: Acute-Phase Proteins; Animals; Aspirin; Electrophoresis, Polyacrylamide Gel; Female; Indomethacin; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Mycobacterium bovis; Propionibacterium acnes; Sex Factors; Sulindac	1987
Radioimmunoassay measurement of 2,3-dinor metabolites of prostacyclin and thromboxane in human urine. Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17B Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Female; Humans; Kidney; Male; Radioimmunoassay; Sulindac; Thromboxane B2	1987
Altered renal and platelet arachidonic acid metabolism in cirrhosis. Gastroenterology, 1986, Volume: 90, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Adult; Aged; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Creatinine; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Epoprostenol; Female; Humans; Kidney; Liver Cirrhosis; Male; Middle Aged; Natriuresis; Prostaglandins E; Prostaglandins F; Renin-Angiotensin System; Sulindac; Thromboxane A2; Thromboxane B2	1986
Effect of aspirin and sulindac in rabbit nephrotoxic nephritis. The Journal of laboratory and clinical medicine, 1986, Volume: 107, Issue:3 Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Basement Membrane; Blood Platelets; Cyclooxygenase Inhibitors; Indenes; Kidney Glomerulus; Male; Nephritis; Prostaglandins; Rabbits; Sulindac; Thromboxanes	1986
Effects of five non-steroidal anti-inflammatory drugs on the renal and systemic responses to arachidonate in conscious dogs. Clinical and experimental pharmacology & physiology, 1987, Volume: 14, Issue:8 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Dinoprostone; Dogs; Ibuprofen; Indomethacin; Kidney; Kidney Cortex; Microsomes; Phenylbutazone; Prostaglandins; Prostaglandins E; Sulindac	1987
Effect of combined treatment of anti-inflammatory drug and mannoheptulose on the production of tumour necrosis factor and endotoxin shock in mice. Cancer letters, 1988, Volume: 39, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Aspirin; Drug Therapy, Combination; Heptoses; Lipopolysaccharides; Male; Mannoheptulose; Mice; Mice, Inbred ICR; Shock, Septic; Sulindac; Tumor Necrosis Factor-alpha	1988
Inhibition of trans-dihydrodiol oxidation by the non-steroidal anti-inflammatory drugs. Carcinogenesis, 1986, Volume: 7, Issue:4 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Anti-Inflammatory Agents; Aspirin; Benzopyrenes; Dihydroxydihydrobenzopyrenes; Flufenamic Acid; Ibuprofen; Indomethacin; Liver; Male; Meclofenamic Acid; Mefenamic Acid; Oxidoreductases; Rats; Sulindac; Tolmetin	1986
Structural damage and changes in eicosanoid metabolites in the gastric mucosa of rats and pigs induced by anti-inflammatory drugs of varying ulcerogenicity. International journal of tissue reactions, 1986, Volume: 8, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Aspirin; Diflunisal; Gastric Mucosa; Indomethacin; Membrane Potentials; Microscopy, Electron; Phenylacetates; Piroxicam; Propionates; Prostaglandins; Rats; Stomach Ulcer; Sulindac; Swine; Thiazines	1986
The effects of sulindac and its metabolites on acute stress-induced gastric ulcers in rats. Toxicology and applied pharmacology, 1986, Volume: 83, Issue:2 Topics: Administration, Oral; Animals; Aspirin; Cold Temperature; Immobilization; Indenes; Male; Peptic Ulcer; Rats; Rats, Inbred Strains; Stress, Psychological; Sulindac	1986
[Hepatotoxicity of non-steroidal anti-inflammatory drugs]. La Clinica terapeutica, 1985, Apr-15, Volume: 113, Issue:1 Topics: Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Child; Female; Humans; Indoles; Liver; Liver Function Tests; Male; Middle Aged; Phenylacetates; Phenylpropionates; Pyrazoles; Pyrroles; Salicylates; Sulindac	1985
Worldwide experience with diclofenac in rheumatoid arthritis and osteoarthritis. Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:2 Suppl 1 Topics: Arthritis, Rheumatoid; Aspirin; Diclofenac; Double-Blind Method; Humans; Indomethacin; Naproxen; Osteoarthritis; Sulindac; Tolmetin	1985
Evidence for a renal origin of urinary thromboxane B2 in health and disease. Advances in prostaglandin, thromboxane, and leukotriene research, 1983, Volume: 11 Topics: Adult; Aspirin; Blood Platelets; Female; Glomerulonephritis; Humans; Kidney; Kinetics; Reference Values; Sulindac; Thromboxane B2; Thromboxanes	1983
Pharmacokinetics of ibuprofen. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Acetaminophen; Adult; Age Factors; Aged; Arthritis, Rheumatoid; Aspirin; Biological Availability; Chromatography, Gas; Chromatography, High Pressure Liquid; Drug Interactions; Female; Humans; Ibuprofen; Intestinal Absorption; Kinetics; Liver Diseases, Alcoholic; Male; Milk, Human; Models, Chemical; Sulindac; Time Factors	1984
Effects of salicylates and other nonsteroidal anti-inflammatory drugs on articular cartilage. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: Animals; Anti-Inflammatory Agents; Aspirin; Atrophy; Cartilage, Articular; Dogs; Extracellular Matrix; Glycosaminoglycans; Indomethacin; Osteoarthritis; Prostaglandin Antagonists; Proteoglycans; Salicylates; Sulfur Radioisotopes; Sulindac; Uronic Acids	1984
A clinical evaluation of the antiarthritic agents. Comprehensive therapy, 1984, Volume: 10, Issue:8 Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis; Aspirin; Diflunisal; Fenoprofen; Glucocorticoids; Gold; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Naproxen; ortho-Aminobenzoates; Penicillamine; Piroxicam; Prostaglandin Antagonists; Salicylates; Sulindac; Thiazines; Tolmetin	1984
Effect on the human complement system of the major non-steroidal anti-inflammatory drugs: aspirin, indomethacin, phenylbutazone, oxyphenbutazone and sulindac. Clinical and experimental immunology, 1983, Volume: 53, Issue:3 Topics: Anti-Inflammatory Agents; Aspirin; Centrifugation, Density Gradient; Chromatography, Gel; Complement C3b Inactivator Proteins; Complement C5; Complement Inactivator Proteins; Complement Pathway, Classical; Dose-Response Relationship, Drug; Hemolysis; Humans; In Vitro Techniques; Indomethacin; Macromolecular Substances; Oxyphenbutazone; Phenylbutazone; Sulindac	1983
Differential effect of three cyclooxygenase inhibitors on human cerebral blood flow velocity and carbon dioxide reactivity. Stroke, 1994, Volume: 25, Issue:9 Topics: Adult; Analysis of Variance; Aspirin; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Humans; Indomethacin; Sulindac; Time Factors; Ultrasonography; Vasoconstriction; Vasodilation	1994
Differential activity of aspirin, ketoprofen and sulindac as cancer chemopreventive agents in the mouse urinary bladder. Carcinogenesis, 1996, Volume: 17, Issue:7 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Butylhydroxybutylnitrosamine; Carcinogens; Diet; Humans; Ketoprofen; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Sulindac; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms	1996
Ibuprofen inhibits the metabolism of the endogenous cannabimimetic agent anandamide. Pharmacology & toxicology, 1997, Volume: 80, Issue:2 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Benzoxazines; Calcium Channel Blockers; Cerebellum; Endocannabinoids; Ibuprofen; Kinetics; Membranes; Morpholines; Naphthalenes; Polyunsaturated Alkamides; Radioligand Assay; Rats; Sulindac	1997
Effects of nonsteroidal anti-inflammatory drugs on glutathione S-transferases of the rat digestive tract. Carcinogenesis, 1997, Volume: 18, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Cytosol; Digestive System; Dose-Response Relationship, Drug; Enzyme Induction; Esophagus; Glutathione; Glutathione Transferase; Ibuprofen; Indomethacin; Intestines; Isoenzymes; Liver; Male; Organ Specificity; Piroxicam; Rats; Rats, Wistar; Stomach; Substrate Specificity; Sulindac	1997
Chemopreventive efficacies of aspirin and sulindac against lung tumorigenesis in A/J mice. Carcinogenesis, 1997, Volume: 18, Issue:5 Topics: Adenoma; Animals; Aspirin; Cells, Cultured; Cytochrome P-450 CYP1A2; Enzyme Activation; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Prodrugs; Sulindac	1997
Recovery from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced immunosuppression in A/J mice by treatment with nonsteroidal anti-inflammatory drugs. Journal of the National Cancer Institute, 1997, Jun-18, Volume: 89, Issue:12 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Antibody-Producing Cells; Aspirin; Carcinogens; Dinoprostone; Female; Immunity, Cellular; Killer Cells, Natural; Mice; Mice, Inbred A; Naproxen; Nitrosamines; Spleen; Sulindac	1997
Nonsteroidal anti-inflammatory drugs enhance glutathione S-transferase theta levels in rat colon. Biochimica et biophysica acta, 1998, Aug-24, Volume: 1381, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Colon; Colonic Neoplasms; Diet; Glutathione Transferase; Ibuprofen; Indomethacin; Male; Nabumetone; Piroxicam; Rats; Rats, Wistar; Sulindac	1998
Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection. Proceedings of the National Academy of Sciences of the United States of America, 1998, Sep-15, Volume: 95, Issue:19 Topics: Adaptor Proteins, Signal Transducing; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Carrier Proteins; Chemoprevention; Clone Cells; Cloning, Molecular; Colorectal Neoplasms, Hereditary Nonpolyposis; DNA Repair; DNA-Binding Proteins; Fungal Proteins; Humans; Microsatellite Repeats; Mutation; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Phenotype; Proto-Oncogene Proteins; Saccharomyces cerevisiae Proteins; Sulindac; Time Factors; Tumor Cells, Cultured	1998
Colorectal cancer--chemoprevention. Journal of the Mississippi State Medical Association, 1998, Volume: 39, Issue:9 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Neoplasms; Folic Acid; Humans; Rectal Neoplasms; Selenium; Sulindac	1998
[Do aspirin or nonsteroidal anti-inflammatory drugs decrease the risk of colorectal cancer?]. Gastroenterologie clinique et biologique, 1998, Volume: 22, Issue:3 Suppl Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Humans; Risk; Sulindac	1998
Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidal anti-inflammatory drugs. British journal of pharmacology, 1999, Volume: 126, Issue:8 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Blood Pressure; Carcinoma; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indans; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salicylates; Substrate Specificity; Sulfonamides; Sulindac; Thromboxane B2; Tumor Cells, Cultured	1999
Overexpression of cyclooxygenase-2 protein is less frequent in gastric cancers with microsatellite instability. International journal of cancer, 1999, Aug-20, Volume: 84, Issue:4 Topics: Adaptor Proteins, Signal Transducing; Aspirin; Base Pair Mismatch; Carrier Proteins; Cyclooxygenase 2; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Lymphatic Metastasis; Male; Membrane Proteins; Microsatellite Repeats; MutL Protein Homolog 1; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Staging; Nuclear Proteins; Phenotype; Prostaglandin-Endoperoxide Synthases; Stomach Neoplasms; Sulindac; Tumor Cells, Cultured	1999
Effects of sulindac, sulindac metabolites, and aspirin on the activity of detoxification enzymes in HT-29 human colon adenocarcinoma cells. Cancer letters, 1999, Dec-01, Volume: 147, Issue:1-2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Enzyme Induction; Glutathione Transferase; HT29 Cells; Humans; NAD(P)H Dehydrogenase (Quinone); Sulindac; Tumor Cells, Cultured	1999
Intestinal tumor load in the Min/+ mouse model is not correlated with eicosanoid biosynthesis. Advances in experimental medicine and biology, 1999, Volume: 469 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Dinoprostone; Eicosanoids; Genes, APC; Indomethacin; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Sulindac	1999
[Therapy and after-care of familial adenomatous polyposis and hereditary colorectal carcinoma without polyposis]. Deutsche medizinische Wochenschrift (1946), 2000, Feb-18, Volume: 125, Issue:7 Topics: Adenomatous Polyposis Coli; Adolescent; Adult; Aftercare; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Colectomy; Colorectal Neoplasms, Hereditary Nonpolyposis; Combined Modality Therapy; Endoscopy, Gastrointestinal; Female; Humans; Male; Sulindac	2000
Analysis of domains in the IKKalpha and IKKbeta proteins that regulate their kinase activity. The Journal of biological chemistry, 2000, May-12, Volume: 275, Issue:19 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Base Sequence; COS Cells; Dimerization; DNA Primers; Enzyme Inhibitors; Helix-Loop-Helix Motifs; I-kappa B Kinase; Mice; NF-kappa B; Protein Conformation; Protein Serine-Threonine Kinases; Sulindac	2000
Sulindac inhibits neointimal formation after arterial injury in wild-type and apolipoprotein E-deficient mice. Proceedings of the National Academy of Sciences of the United States of America, 2000, Nov-07, Volume: 97, Issue:23 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins E; Apoptosis; Aspirin; Cell Division; Cholesterol; Female; Femoral Artery; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Sulindac	2000
Growth-suppressive effect of non-steroidal anti-inflammatory drugs on 11 colon-cancer cell lines and fluorescence differential display of genes whose expression is influenced by sulindac. International journal of cancer, 2000, Dec-15, Volume: 88, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Cell Cycle; Cell Size; Cell Survival; Colonic Neoplasms; DNA, Complementary; DNA, Neoplasm; HT29 Cells; Humans; Reverse Transcriptase Polymerase Chain Reaction; Sulindac; Tumor Cells, Cultured	2000
Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) alter the kinetics of human colon cancer cell lines more effectively than traditional NSAIDs: implications for colon cancer chemoprevention. Cancer research, 2001, Apr-15, Volume: 61, Issue:8 Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Aspirin; Cell Cycle; Cell Division; Colon; Colonic Neoplasms; Growth Inhibitors; HT29 Cells; Humans; Ibuprofen; Nitric Oxide Donors; Sulindac; Tumor Cells, Cultured	2001
Inhibition of store-operated calcium entry contributes to the anti-proliferative effect of non-steroidal anti-inflammatory drugs in human colon cancer cells. International journal of cancer, 2001, Jun-15, Volume: 92, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Calcium; Cell Cycle; Cell Division; Cell Separation; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Flow Cytometry; Humans; Inhibitory Concentration 50; Lanthanum; Lipid Metabolism; Mefenamic Acid; Pyridines; Sulindac; Thapsigargin; Time Factors; Triazoles; Tumor Cells, Cultured	2001
Aspirin inhibits matrix metalloproteinase-2 activity, increases E-cadherin production, and inhibits in vitro invasion of tumor cells. Biochemical and biophysical research communications, 2001, Apr-06, Volume: 282, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cadherins; Cell Movement; Cyclooxygenase Inhibitors; Humans; Matrix Metalloproteinase Inhibitors; Neoplasm Invasiveness; Protease Inhibitors; Sulindac; Tumor Cells, Cultured	2001
Dysregulation of integrin-linked kinase (ILK) signaling in colonic polyposis. Oncogene, 2001, Sep-27, Volume: 20, Issue:43 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonic Polyps; Disease Progression; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Enzymologic; Humans; Mutation; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Signal Transduction; Sulindac; Time Factors; Tumor Cells, Cultured	2001
Expression profile analysis of colon cancer cells in response to sulindac or aspirin. Biochemical and biophysical research communications, 2002, Mar-29, Volume: 292, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Colonic Neoplasms; Down-Regulation; Gene Expression Profiling; Humans; Kinetics; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; RNA, Messenger; RNA, Neoplasm; Sulindac; Tumor Cells, Cultured; Up-Regulation	2002
[Nonsteroidal anti-inflammatory drugs and the risk of polyposis, colon carcinoma and rectal carcinoma]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2002, Volume: 36, Issue:5 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Female; Humans; Ibuprofen; Logistic Models; Male; Middle Aged; Piroxicam; Polyps; Rectal Neoplasms; Risk Factors; Sulindac; Time Factors	2002
The combined treatment of aspirin and radiation induces apoptosis by the regulation of bcl-2 and caspase-3 in human cervical cancer cell. Cancer letters, 2003, Jan-28, Volume: 189, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase 3; Caspases; Cell Division; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Gamma Rays; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Genes, p53; HeLa Cells; Humans; Indomethacin; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Radiation Tolerance; Radiation-Sensitizing Agents; Sulindac; Tumor Stem Cell Assay; Tumor Suppressor Protein p53	2003
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit vascular smooth muscle cell proliferation via differential effects on the cell cycle. The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Cell Division; Cell Line; Diclofenac; Dose-Response Relationship, Drug; Flow Cytometry; Ibuprofen; Indomethacin; Muscle, Smooth, Vascular; Rats; Sodium Salicylate; Sulindac	2003
[Inhibition of vascular smooth muscle cell proliferation by non-steroidal anti-inflammatory drugs]. Shi yan sheng wu xue bao, 2003, Volume: 36, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Cycle; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Ibuprofen; Muscle, Smooth, Vascular; Rats; Sulindac	2003
Chemopreventive agents induce oxidative stress in cancer cells leading to COX-2 overexpression and COX-2-independent cell death. Carcinogenesis, 2009, Volume: 30, Issue:1 Topics: Anticarcinogenic Agents; Apoptosis; Aspirin; Blotting, Western; Cell Division; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Humans; Microscopy, Fluorescence; Oxidative Stress; RNA, Small Interfering; Structure-Activity Relationship; Sulindac	2009
TNF-related apoptosis-inducing ligand cooperates with NSAIDs via activated Wnt signalling in (pre)malignant colon cells. The Journal of pathology, 2011, Volume: 223, Issue:3 Topics: Adenoma; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Aspirin; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Caco-2 Cells; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Neoplasm Proteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; Recombinant Proteins; Signal Transduction; Sulindac; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor 4; Transcription Factors; Tumor Cells, Cultured; Wnt Proteins	2011
The novel phospho-non-steroidal anti-inflammatory drugs, OXT-328, MDC-22 and MDC-917, inhibit adjuvant-induced arthritis in rats. British journal of pharmacology, 2011, Volume: 162, Issue:7 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Cell Line; Cytokines; Dinoprostone; Gastrointestinal Diseases; Humans; Ibuprofen; Jurkat Cells; Mice; NF-kappa B; NIH 3T3 Cells; Organophosphates; Organophosphorus Compounds; Rats; Sulindac	2011
[Antitumor effects of sulindac in ovarian cell cultures]. Ginekologia polska, 2011, Volume: 82, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Cell Cycle; Cell Size; Cell Survival; Colorimetry; Female; Humans; Lactones; Ovarian Neoplasms; Sulfonamides; Sulfones; Sulindac; Tumor Cells, Cultured	2011
Facilitation of human osteoblast apoptosis by sulindac and indomethacin under hypoxic injury. Journal of cellular biochemistry, 2012, Volume: 113, Issue:1 Topics: Alkaline Phosphatase; Animals; Apoptosis; Aspirin; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Cellular Microenvironment; Cobalt; Cyclooxygenase 2; Deferoxamine; Female; Fractures, Bone; Humans; Indomethacin; Mice; Osteoblasts; Poly(ADP-ribose) Polymerases; Sodium Salicylate; Sulindac	2012
Chemotherapeutic properties of phospho-nonsteroidal anti-inflammatory drugs, a new class of anticancer compounds. Cancer research, 2011, Dec-15, Volume: 71, Issue:24 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; HT29 Cells; Humans; Immunoblotting; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms; NF-kappa B; Organophosphates; Sulindac; Thioredoxin-Disulfide Reductase; Thioredoxins; Time Factors; Xenograft Model Antitumor Assays	2011
Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity. The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Line, Tumor; Cell Survival; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Female; HEK293 Cells; Humans; Hydrolysis; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Kinetics; Mice; Mice, Inbred BALB C; Mice, Nude; Naproxen; Nitrophenols; Organophosphates; Organophosphorus Compounds; Phenylglyoxal; Stomach Neoplasms; Sulindac; Transfection; Valproic Acid; Xenograft Model Antitumor Assays	2012
Hydrogen sulfide-releasing NSAIDs inhibit the growth of human cancer cells: a general property and evidence of a tissue type-independent effect. Biochemical pharmacology, 2012, Mar-15, Volume: 83, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Aspirin; Cell Line, Tumor; Cell Proliferation; Growth Inhibitors; Humans; Hydrogen Sulfide; Ibuprofen; Naproxen; Sulindac; Thiones	2012
[Effects of NF-kappaB inhibitor on cisplatin-induced apoptosis in cervical cancer]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2013, Volume: 44, Issue:1 Topics: Apoptosis; Aspirin; Cell Cycle; Cell Line, Tumor; Cell Survival; Cisplatin; Curcumin; Female; Humans; NF-kappa B; Pyrrolidines; Sulindac; Thiocarbamates; Uterine Cervical Neoplasms	2013
The chemopreventive efficacies of nonsteroidal anti-inflammatory drugs: the relationship of short-term biomarkers to long-term skin tumor outcome. Cancer prevention research (Philadelphia, Pa.), 2013, Volume: 6, Issue:7 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Biomarkers, Tumor; Blotting, Western; Cell Proliferation; Cells, Cultured; Dinoprostone; Female; Humans; Keratinocytes; Mice; Mice, Hairless; Naproxen; Skin Neoplasms; Sulindac; Ultraviolet Rays	2013
Phospho-NSAIDs have enhanced efficacy in mice lacking plasma carboxylesterase: implications for their clinical pharmacology. Pharmaceutical research, 2015, Volume: 32, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carboxylic Ester Hydrolases; Carcinoma, Lewis Lung; Ibuprofen; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organophosphates; Organophosphorus Compounds; Sulindac	2015
Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs. Carcinogenesis, 2015, Volume: 36, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Azoxymethane; Carcinogens; Celecoxib; Chemoprevention; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Hydroxyprostaglandin Dehydrogenases; Inflammation; Intestinal Mucosa; Membrane Proteins; Mice; Mice, Knockout; Pyrazoles; Sulfonamides; Sulindac	2015
Identification of the Effects of Aspirin and Sulindac Sulfide on the Inhibition of HMGA2-Mediated Oncogenic Capacities in Colorectal Cancer. Molecules (Basel, Switzerland), 2020, Aug-22, Volume: 25, Issue:17 Topics: Aspirin; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Cytotoxins; HMGA2 Protein; Humans; Neoplasm Proteins; Sulindac	2020
Aspirin and Sulindac act via different mechanisms to inhibit store-operated calcium channel: Implications for colorectal cancer metastasis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 145 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caco-2 Cells; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cell Movement; Colorectal Neoplasms; Humans; Intracellular Calcium-Sensing Proteins; Membrane Proteins; Neoplasm Metastasis; Prodrugs; Sulindac	2022