aspirin has been researched along with salicylates in 1503 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1178 (78.38) | 18.7374 |
| 1990's | 189 (12.57) | 18.2507 |
| 2000's | 79 (5.26) | 29.6817 |
| 2010's | 46 (3.06) | 24.3611 |
| 2020's | 11 (0.73) | 2.80 |
| Authors | Studies |
|---|---|
| Rainsford, KD | 3 |
| Keinänen, S; Kouvalainen, K; Similä, S | 1 |
| Humphreys, KJ; Smy, JR | 1 |
| Khalili-Varasteh, H; Legros, J; Rosner, I | 1 |
| Aures, D; Bugat, R; Grossman, MI; Thompson, MR | 1 |
| Anderson, JA; Buchanan, WW; Lee, P; Miller, J; Webb, J | 1 |
| Ciontescu, L; Cîrje, M; Cîrstea, M; Suhaciu, G | 1 |
| Asker, AF; Whitworth, CW | 3 |
| Lefort, J; Vargaftig, BB | 3 |
| Sorenson, JR | 1 |
| Bennett, A; Curwain, BP | 1 |
| Berg, KJ | 1 |
| Barron, G; Dewar, AJ; Reading, HW | 1 |
| Baudinette, RV; Tonkin, AL; Wheldrake, JF | 1 |
| Bare, JJ; Helms, RJ; Johnson, N; Leeling, JL; Muni, IA; Phillips, BM | 1 |
| Davison, C; Dorrbecker, BR; Edelson, J | 1 |
| Vargaftig, BB | 2 |
| Hayden, LJ; Thomas, G; West, GB | 1 |
| Koeppe, P; Palme, G | 1 |
| Efentakis, E; Fell, JT | 1 |
| Alonso, S; Armijo, M; Ortega, P; Piña, M | 1 |
| Alonso, S; Navarro, JL; Ortega, P | 1 |
| Alonso, S; Maroto, L; Ortega, P; Priego, J | 1 |
| Armijo, M; Piña, M | 1 |
| Riding, GV | 1 |
| Billimoria, JD; Kumar, R | 1 |
| Warne, PJ; West, GB | 1 |
| Alonso, S; Armijo, M; Piña, M | 1 |
| Alonso, S; Armijo, M; Cillero, F; Piña, M; Sunkel, C | 1 |
| Collins, C; Laird, RI; Richards, PT; Starmer, GA; Weyrauch, S | 1 |
| Collins, C; Laird, R; Richards, PT; Starmer, GA; Weyrauch, S | 1 |
| Smith, MJ; Walker, JR | 1 |
| Cochrane, P; Tringham, VM | 1 |
| Bianchi Porro, G; Caruso, I; Fumagalli, M; Lazzaroni, M; Montrone, F; Petrillo, M | 1 |
| Smith, MJ | 5 |
| Diamantis, W; Haertlein, B; Kohlhepp, WC; Melton, J; Sofia, RD | 1 |
| Petersen, JK | 1 |
| Cuatrecasas, P; McConnell, RT; Siegel, MI | 1 |
| Whittle, BJ | 1 |
| John, VA | 1 |
| Ali, M; McDonald, JW | 1 |
| Franz, TJ | 2 |
| Berry, D; Gibson, T; Grove, J; Widdop, B; Zaphiropoulos, G | 2 |
| Cendelin, E; Fröhlich, M | 1 |
| Beaven, MA; De Mello, MC; Moss, J; Vaughan, M | 1 |
| Faure, G; Gaucher, A; Netter, P; Royer, RJ; Tamisier, JN | 1 |
| Garcia Rafanell, J; Planas, JM; Puig-Parellada, P | 1 |
| Buchanan, N; Eyberg, C; Kundig, H | 1 |
| Garrettson, LK; Levy, G; Procknal, JA | 1 |
| Jordan, BJ; Nichols, JD; Rance, MJ | 1 |
| Blackwell, GJ; Flower, RJ; Vane, JR | 1 |
| Elliott, PN; Ford-Hutchinson, AW; Smith, MJ | 1 |
| Garrettson, LK; Kamath, BL; Lampman, T; Levy, G | 1 |
| Jacobs, RP | 1 |
| Brune, K; Graf, P; Rainsford, KD | 1 |
| McQueen, EG | 1 |
| Marcus, SM | 1 |
| Itami, T; Kanoh, S | 3 |
| Castellion, AW; Goldenberg, MM; Honkomp, LJ | 1 |
| Kunin, CM; Proctor, RA | 1 |
| Ferber-Perret, F; Perrier, CV; Schulz, P; Steelman, SL; VandenHeuvel, WJ | 1 |
| Cohen, A | 1 |
| Evens, RP | 1 |
| Carter, GW; Cimon, DG; Garmaise, DL; Paris, GY; Swett, L; Young, P | 2 |
| Ducluzeau, R; Faivre, J; Faivre, M; Lery, N; Moulinier, B; Paliard, P | 1 |
| Mowat, AG | 1 |
| Rodda, B; Van Winzum, C | 1 |
| Andrew, A; Rodda, B; Van Winzum, C; Verhaest, L | 1 |
| Hannah, J; Holtz, WJ; Houser, RW; Jones, H; Kelly, KW; Matzuk, AR; Ruyle, WV; Sarett, LH; Shen, TY; Witzel, BE | 1 |
| Najjar, TA | 1 |
| Fröhlich, M; Wichmann, G | 1 |
| Krantz, JC | 1 |
| Ardlie, NG; Brune, K; Rainsford, KD; Whitehouse, MW; Young, IG | 1 |
| Landecker, KD; Piper, DW; Thomas, JH; Wellington, JE | 1 |
| Barden, TP; Bloomfield, SS; Mitchell, J | 1 |
| Karim, SM | 1 |
| Daurio, C; De Roo, M; DeSchepper, PJ; Steelman, SL; Tempero, KF; Tjandramaga, TB; Verhaest, L | 1 |
| Cremer, CW; Honig, WJ; Manni, JG | 1 |
| Champion, GD; Corrigan, AB; Day, RO; Graham, GG; Haski, A; Hewson, J; Howe, GB; Paull, PD | 1 |
| Liyanage, SP; Tambar, PK | 1 |
| Gyles, CL; Zigler, M | 1 |
| Mäkelä, AL; Yrjänä, T | 1 |
| Roldán, A; San Martín, J | 1 |
| Hicklin, JA | 1 |
| Buchanan, MR; Carter, CJ; Hirsh, J; Kelton, JG | 1 |
| Agarwal, A; Burgi, E; Findlay, R; Hinderer, K; Jardini, L | 1 |
| Grayson, MF | 1 |
| Dieppe, PA; Huskisson, EC | 1 |
| Huskisson, EC | 1 |
| Blechman, WJ; Lechner, BL | 1 |
| Rothschild, BM | 1 |
| Elis, J; Matĕjovská, D; Polák, L; Raska, K; Rasková, H; Sechser, T; Sechserová, M; Vanĕcek, J | 1 |
| Ashworth, ME; Ferry, DG; Grennan, DM; Kenny, RE; Mackinnon, M | 1 |
| Majerus, PW; Stanford, N | 1 |
| Fradkin, R; Ritter, EJ; Scott, WJ; Wilson, JG | 1 |
| Cuny, G; Faure, G; Maillard, A; Mur, JM; Netter, P; Penin, F; Royer, RJ; Serot, JM | 1 |
| Day, RO; Lindsley, HB | 1 |
| Franzini, P | 1 |
| Kaspi, T; Orton, D; Richardson, R; Treharne Jones, R | 1 |
| Hanson, A; Lindroth, Y; Sjöblom, KG; Wollheim, FA | 1 |
| Bochner, F; Cham, BE; Imhoff, DM; Johns, D; Rowland, M | 2 |
| Luber, JR; Patel, DM; Visalli, AJ | 1 |
| Brooks, PM; Roberts, MS; Rumble, RH | 2 |
| Spisani, S; Traniello, S; Vanzini, G | 1 |
| Baum, J; Orozco-Alcala, JJ | 1 |
| Juhl, RP | 1 |
| Buchanan, MR; Gent, M; Hirsh, J; Lawrence, W; Rosenfeld, J | 1 |
| Kirchhoefer, RD; Reepmeyer, JC | 1 |
| Alexander, F; Dubb, JW; Familiar, RG; Hwang, BV; Maass, AR; Stote, RM | 1 |
| Amezcua, JL; Moncada, S; O'Grady, J; Salmon, JA | 1 |
| Bradbrook, ID; Morrison, PJ; Rogers, HJ; Spector, RG | 1 |
| Makki, KA; O'Grady, J; Whittle, BJ | 1 |
| Rumack, BH | 1 |
| Ford-Hutchinson, AW; Slack, JA; Smith, MJ; Walker, JR | 1 |
| Abbott, FS; Au, DS; Tam, YK | 1 |
| Jacobs, JC | 1 |
| Markiewicz, A; Semenowicz, K | 1 |
| Hrsak, I; Szirmai, E | 1 |
| Bare, J; Leeling, J; Medon, P | 1 |
| Elis, J; Polák, L; Rasková, H; Sechser, T; Sechserová, M; Vanĕcek, J | 1 |
| Famewo, CE; Garvey, MB; Noble, WH | 1 |
| de Gaetano, G; Donati, MB; Garattini, S | 1 |
| Hindson, C | 1 |
| Kirkwood, AH; Longauer, JK; Weirich, EG | 3 |
| Baum, RG; Cantwell, FF | 2 |
| Giacomini, KM; Levy, G | 1 |
| Brem, J; Miller, TB | 1 |
| Sofia, RD | 1 |
| Aures, D; Grossman, MI; Hansen, DG | 1 |
| Tani, S | 1 |
| Iranloye, TA; Parrott, EL | 1 |
| Chiou, WL; Gadalla, MA; Peng, A; Peng, GW; Smith, V | 1 |
| Chrastil, J; Wilson, JT | 1 |
| Soren, A | 2 |
| Arena, FP; Dugowson, C; Saudek, CD | 1 |
| Elfving, SM; Elonen, E; Neuvonen, PJ | 1 |
| Blair, D; Peterson, RG; Rumack, BH | 1 |
| Colaizzi, JL; Jaffe, JM; Scholtz, EC | 1 |
| Miller, RR | 1 |
| Hallquist, SL; Koch, PA; Schultz, CA; Welling, PG; Wills, RJ | 1 |
| Levy, G | 4 |
| Besselaar, GH; Breault, GO; Czerwinski, AW; Davis, RL; Duggan, DE; Kwan, KC; Lei, BW | 1 |
| Okabe, S; Takagi, K; Takeuchi, K; Urushidani, T | 1 |
| Byczkowski, JZ; Hać, EE | 1 |
| Johnston, PV; Weston, PG | 1 |
| Weirich, EG | 1 |
| Fowles, M; Wigley, RA | 1 |
| Cohen, LS | 1 |
| Ellis, CH; Selph, JL; Truax, JF; Vinegar, R; Welch, RM; White, HL | 1 |
| Canada, AT; Creighton, EL; Little, AH | 1 |
| Focesi, A; Vercesi, AE | 1 |
| Goldberg, R; Nightingale, CH | 1 |
| Bernstein, BH; Hanson, V; King, KK; Singsen, BH | 1 |
| Goodman, MJ; Kent, PW; Truelove, SC | 2 |
| Samter, M | 1 |
| Lehtola, J; Linnoila, M | 1 |
| Kaye, CM; Parsons, RL; Raymond, K | 1 |
| Rainsford, KD; Whitehouse, MW | 3 |
| Cotty, VF; Ederma, H; Hunter, D; Lehr, M; Melman, K; Mueller, F; Skerpac, J; Sterbenz, FJ | 1 |
| Champion, GD; Day, RO; Graham, GG; Paull, PD | 2 |
| Andersson, I; Jansson, SO | 1 |
| Ansell, BM; Fowler, PD; Hall, MA; Moran, H | 1 |
| Hundt, HK; Müller, DG; Müller, FO | 1 |
| Buniva, G; Dubini, A; Nicolis, FG | 1 |
| Lutz, UC; Weirich, EG | 1 |
| Day, DK; Roberts, RJ; Williamson, HE | 1 |
| Bucur, I; Monti, M | 1 |
| Gaylarde, PM; Sarkany, I | 1 |
| Gould, WA; Haslock, I; Strickland-Hodge, B; Thomas, TR | 1 |
| Andreasen, AC; Lynd, PA; Wyatt, RJ | 1 |
| Ali, SL | 2 |
| Gustafson, A; Gustafsson, B | 1 |
| Quiroga, E; Sack, ES | 1 |
| Christie, D; Kincaid-Smith, P; McPherson, L | 1 |
| Trnavský, K; Zachar, M | 2 |
| Brunstein, SL; Calabro, JJ; Staley, HL | 1 |
| Chepovskiĭ, VS; Makar, DA; Pavlovskiĭ, MP | 1 |
| Fossati, C | 1 |
| Jörgensen, TG; Nielsen, HH; Olesen, HP; Weis-Fogh, US | 1 |
| Bonardi, G; Montanari, C; Prandoni, E; Sala, P | 1 |
| Berg, KJ; Bergan, A | 1 |
| Barraclough, DR; Laby, B; Muirden, KD | 1 |
| Pohto, P | 1 |
| Barraclough, DR; Muirden, KD | 1 |
| Gurtoo, HL; Hartnagel, RE; Leeling, JL; Phillips, BM | 1 |
| Gauzeran, D | 1 |
| Crout, JE; Hepburn, B; Ritts, RE | 1 |
| Domellöf, L; Sönne, B | 1 |
| Roe, RL | 1 |
| Beaven, MA; Horakova, Z; Keiser, HR | 1 |
| Leonards, JR | 2 |
| Gallery, E; Mahony, JF; McCarthy, SW; Roberts, BA; Stewart, JH; Storey, BG | 1 |
| Gupta, N; Paulus, HE; Sarkissian, E | 1 |
| Doelker, E; Mordier, D; Schwyter, H | 1 |
| Buchanan, N | 1 |
| Schlumberger, HD | 1 |
| Boréus, LO; Faxelius, G; Windorfer, A | 1 |
| Ratnikov, VI | 1 |
| Gault, MH | 1 |
| Brant, RJ; Yeary, RA | 1 |
| Levy, G; Yacobi, A | 1 |
| Lee, KH; Thompkins, L | 2 |
| Parrott, EL | 1 |
| Bouhuys, A; Douglas, JS; Orehek, J | 1 |
| Laaksonen, AL; Yrjänä, T | 1 |
| Castania, A; Cordeiro, RS; Rothschild, AM | 1 |
| Davis, K; Hoth, M; Smith, MJ | 1 |
| Pütter, J | 1 |
| Daneels, R; Loew, D; Pütter, J | 1 |
| Abdel Hadi, I; Kedvessy, G; Morvay, J | 1 |
| Baggot, JD; Gingerich, DA; Yeary, RA | 1 |
| Koivikko, A; Mäkelä, AL; Sillanpää, M | 1 |
| Cressman, WA; Lopez, B; Summer, D | 1 |
| Delbecque, H; Fruchart, JC; Warembourg, H | 1 |
| Brath, HK; Hansen, T; Kaldestad, E | 1 |
| Dijk, A; Drost, RH; Lindkaer-Jensen, S; Maes, RA; Sorensen, PN | 1 |
| Elis, J; Jecná, J; Rasková, H; Sechser, T; Sechserová, M; Vanecek, J | 1 |
| Bojesen, E; Grunnet, I | 1 |
| Glader, BE | 1 |
| Liebhaber, MI; Rosenfeld, RG | 1 |
| Cressman, WA; Plostnieks, J; Wortham, GF | 1 |
| Kowalski, RL; Kowalski, TL; Leeling, JL; Phillips, BM | 1 |
| Champion, GD; Graham, GG | 1 |
| Matsuo, N; Saji, T; Umezawa, T | 1 |
| Lücker, PW; Rogalla, K; Schettler, T; Wetzelsberger, N | 1 |
| Asako, H; Granger, DN; Kubes, P; Wallace, J; Wolf, RE | 1 |
| Davis, MB; Soybel, DI; West, AB | 1 |
| Gutknecht, J | 1 |
| Acitores, E; Legaz, ME; Valverde, F | 1 |
| Becker, WM; Schlaak, M; Schubeler, K; Schulz, KH; Zhu, D | 1 |
| Chaiyos, N; Itthipanichpong, C; Sirivongs, P; Wittayalertpunya, S | 1 |
| Fresta, M; Micali, N; Puglisi, G; Villari, A | 2 |
| Bianchi, A; Bonina, FP; Bousquet, E; Ciampini, N; Montenegro, L; Tirendi, S | 1 |
| De Mattia, G; Ferro-Luzzi, A; Ghiselli, A; Laurenti, O; Maiani, G | 1 |
| Klimes, J; Sedlácek, J; Sochor, J; Zahradnícek, M | 1 |
| Belliardo, F; Bruno, G; La Rosa, C; Lucarelli, C; Pelloso, R | 1 |
| Bock, R; Jurna, I; Spohrer, B | 1 |
| de la Cruz, JP; Mata, JM; Sanchez de la Cuesta, F | 1 |
| Dorris, RJ | 1 |
| Mayer, AL; Sitar, DS; Tenenbein, M | 1 |
| Hirschowitz, BI; Lanas, A | 1 |
| Birrell, GJ; Grubb, BD; Iggo, A; McQueen, DS | 1 |
| Bernard, H; Boisseau, M; Casadebaig, F; Daret, D; Dupin, JP; Gravier, D; Hou, G; Larrue, J | 1 |
| Bromm, B; Rundshagen, I; Scharein, E | 1 |
| Ito, S; Oka, R; Tsuchida, A; Yoshioka, H | 1 |
| Efstathiou, CE; Ioannou, PC; Konstantianos, DG | 1 |
| Roberts, MS; Shen, JJ; Wanwimolruk, S | 1 |
| Cole, AT; Hawkey, CJ; Hawthorne, AB; Mahida, YR | 1 |
| Clarke, RJ; FitzGerald, GA; Mayo, G; Price, P | 1 |
| Cox-Foster, D; Craig, R; Grazzini, R; Heininger, E; Hesk, D; Hildenbrandt, G; Medford, J; Mumma, RO; Reddy, CC | 1 |
| Albrecht, M; Brandt, KD; O'Bryan-Tear, G | 1 |
| Roth, SH | 2 |
| de Vries, BJ; van den Berg, WB; van der Kraan, PM | 1 |
| Lucarelli, C; Marzo, A; Meroni, G; Quadro, G; Ripamonti, M; Treffner, E | 1 |
| Campos, A; Cervós-Navarro, J; Heye, N; Kannuki, S | 1 |
| Buchanan, WW; Rainsford, KD | 1 |
| Adelman, HM; Flannery, MT; Wallach, PM | 1 |
| Artaza, MA; Castel, JM; Laporte, JR | 1 |
| Bucchi, F; Cerletti, C; Davies, JA; de Gaetano, G; Donati, MB; Hampton, KK; Loizou, LA; Prentice, CR | 1 |
| Dworski, R; Nizankowska, E; Soja, J; Szczeklik, A | 1 |
| Chen, YL; Hong, T; Li, W; Qu, SY; Sun, Y; Zhang, YQ | 1 |
| Florey, KG | 1 |
| Bobbin, RP; Fallon, M; Puel, JL | 1 |
| Bird, HA; Fenn, GC; Hill, J; Lee, CE; Woodward, M; Wright, V | 1 |
| Elta, GH; Scheiman, JM | 1 |
| Vaara, M | 1 |
| Esposito, S; Maggiolo, F; Noviello, S | 1 |
| Umeki, S | 1 |
| King, RL; Levine, RA; Nandi, J | 1 |
| Haginaka, J; Kimura, Y; Wakai, J; Yasuda, H; Yasuda, N | 1 |
| Fontagne, J; Giroud, JP; Maman, L; Pham Huy, D; Revelant, V; Roch-Arveiller, M; Sorenson, JR | 1 |
| Abeles, M; April, P; Baraf, H; Cohen, S; Curran, N; Doucette, M; Ekholm, B; Goldlust, B; Knee, CM; Lee, E | 1 |
| Dworski, R; Nizankowska, E; Szczeklik, A | 1 |
| Bird, HA; Le Gallez, P; Wright, V | 1 |
| Bennett, PN; Notarianni, LJ; Patel, DK | 1 |
| Cryer, B; Feldman, M; Goldschmiedt, M; Redfern, JS | 1 |
| Goldlust, MB; Hougham, AJ; Schrank, PJ; Stevenson, DD; Wilson, RR | 1 |
| Cavrini, V; Di Pietra, AM; Gatti, R | 1 |
| Bennett, PN; Notarianni, LJ; Ogunbona, A; Patel, DK | 1 |
| Giroud, JP; Huy, DP; Maman, L; Roch-Arveiller, M; Sorenson, JR | 1 |
| Kelly, HW; McWilliams, BC; Vertrees, JE | 1 |
| Bennett, PN; Hesse, A; Notarianni, LJ; Ogunbona, A; Patel, DK | 1 |
| Breen, DJ; De Bruyne, JJ; Lam, TJ; Nap, RC | 1 |
| Drennen, JK; Lodder, RA | 1 |
| Hanks, GW | 1 |
| Honma, K; Ishikawa, Y; Saitou, Y | 1 |
| Ankersen, M; Nielsen, KK; Senning, A | 1 |
| Catanese, B; Guglielmotti, A; Martinelli, B; Romanelli, L; Valeri, P | 1 |
| Knottenbelt, DC; Morton, DJ | 1 |
| Corna, D; Garattini, S; Gaspari, F; Locatelli, M; Perico, N; Remuzzi, G | 1 |
| Attardo Parrinello, G; Barzaghi, N; Gatti, G; Perucca, E; Vitiello, B | 1 |
| Fadiran, EO; Salako, Q; Thomas, WO | 1 |
| De Vries, J; Groot, EJ; van Bree, L | 1 |
| Miners, JO | 1 |
| Blain, PG; Moore, U; Mutch, EM; Nicholson, E; Rawlins, MD; Seymour, RA; Williams, FM; Wright, P; Wynne, H | 1 |
| Francis, HW; Friesen, WT; Owen, SG; Roberts, MS | 1 |
| Almeida, MG; Garcia-Leme, J; Sudo, LS; Yasaka, W | 1 |
| Alvarez, L; Castillo-Olivares, JL; de Haro, J; Escudero, MC; Millán, I; Rodríguez, V | 1 |
| Bertko, RJ; Davidovich, A; Finckenor, BA; Gaginella, TS | 1 |
| Bieri, D; Brown, M; Cairns, D; Day, RO; Graham, GG; Harris, G; Hounsell, J; Platt-Hepworth, S; Reeve, R; Sambrook, PN | 1 |
| Altimiras, J; Arís, A; Augé, JM; Bassons, T; Bonal, J; Caralps, JM; Castellarnau, C; Crexells, C; Guiteras, P; Masotti, M | 1 |
| Rumack, BH; Smolinske, SC; Spoerke, DG; Vandenberg, SA | 1 |
| Chai, T; Foulds, J; Murray, DM; Rosner, JL | 1 |
| Barlow, JC; Dillon, EC; Watson, WA; Wilton, JH | 1 |
| Paulus, HE | 1 |
| Rainey, PM | 1 |
| Danesh, BJ; Forbes, CD; Lowe, GD; McLaren, M; Russell, RI | 2 |
| Haginaka, J; Wakai, J; Yasuda, H | 1 |
| Alvarez, L; Castillo-Olivares, JL; del Moral, JH; Escudero-Vela, MC; Millán, I; Rodríguez, V | 1 |
| Birrell, GJ; McQueen, DS; Ritchie, IM | 1 |
| Bogacz, K; Caldron, P | 1 |
| Paulus, HE; Schlegel, SI | 1 |
| Jasiewicz, ML; Richardson, JC | 1 |
| Buyniski, JP; Cavanagh, RL; Schwartz, SE | 1 |
| De Paolis, L; Martinelli, B; Romanelli, L; Valeri, P | 1 |
| Frumkin, A | 1 |
| Behler, EM; Berardi, RR; Elta, GH; Scheiman, JM | 1 |
| Balotta, C; Campoleoni, A; Castelli, MG; Chiabrando, C; Cozzi, E; Fanelli, R; Garattini, S; Latini, R | 1 |
| Bomalaski, JS; Clark, MA; Hirata, F | 1 |
| De la Cruz, JP; Garcia-Arnes, J; Pavia, J; Sanchez de la Cuesta, F | 1 |
| Abramson, S; Edelson, H; Haines, K; Herman, R; Kimmel, S; Korchak, H; Levin, RI; Ludewig, R; Rider, L; Weissmann, G | 1 |
| Cerletti, C; de Gaetano, G; Dejana, E; Latini, R | 1 |
| Bull, R; Haug, A; Mazorow, DL; McGroarty, EJ | 1 |
| Forn, J; García-Rafanell, J; Gomez, L; Ramis, J | 1 |
| Husney, RM; Sagone, AL | 1 |
| Altman, RD | 1 |
| Buchanan, MR; Butt, RW; Hirsh, J; Markham, BA; Nazir, DJ | 1 |
| Fischer, C; Frölich, JC; Meese, CO; Rosenkranz, B | 1 |
| Bernard, H; Boisseau, MR; Casadebaig, F; Dupin, JP; Gravier, D | 1 |
| Aihara, H; Higuchi, S; Otomo, S; Shioiri, Y; Tanaka, N | 1 |
| Henderson, B; Higgs, GA; Salmon, JA; Vane, JR | 1 |
| Cordeiro, RS; Martins, MA; Silva, PM; Vargaftig, BB | 1 |
| Forn, J; García Rafanell, J; Gómez, L | 1 |
| Amezcua, JL; Favari, L; Mourelle, M | 2 |
| Schrör, K; Verheggen, R | 2 |
| Albors, M; De Castellarnau, C; Rutllant, ML; Sancho, MJ; Vila, L | 1 |
| Bucchi, F; Cerletti, C; Chen, ZM; de Gaetano, G; Gambino, MC; Gori, G; Latini, R; Passaghe, S | 1 |
| Bigby, M; Stern, R | 1 |
| Atkinson, DC; Diamond, J; Zambraski, EJ | 1 |
| Bochner, F; Lloyd, JV; Morris, PM; Siebert, DM; Williams, DB | 1 |
| Day, RO; Lam, S; Paull, PD; Swanson, BR; Wade, DN; Williams, KM | 1 |
| Danesh, JZ; Duncan, A; Mitchell, G; Russell, RI | 1 |
| Gouyon, JB; Guignard, JP | 1 |
| Halla, JT; Hardin, JG | 1 |
| Anton, F; Forster, C; Handwerker, HO; Reeh, PW; Weber, E | 1 |
| Bella, G; Messina, G; Russo, S | 1 |
| Cerletti, C; de Gaetano, G; Dejana, E; Domanin, M; Latini, R; Lauri, D; Lorenzi, G; Marchi, S; Urso, R | 1 |
| Allen, A; Garner, A; Rowe, PH | 1 |
| Koren, G | 2 |
| Danesh, BJ; Lowe, GD; Russell, RI; Saniabadi, AR | 1 |
| Artaza, MA; Castel, JM; Cusidó, E; Laporte, JR; Vidal, X | 1 |
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| FRICK, PG | 1 |
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| Abdellatif, KR; Chowdhury, MA; Das, D; Dong, Y; Knaus, EE; Suresh, MR; Velázquez, CA; Yu, G | 1 |
| Cross, KP; Herr, SM; Randell, KA | 1 |
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| BERNSTEIN, M; KRASNOFF, SO | 1 |
| GOETZL, FR; PARSONS, CM | 2 |
| BARLETT, E | 1 |
| GREENBERG, LA; LESTER, D; LOLLI, G | 1 |
| Funaki, H; Ikegaya, H; Kato, H; Kobayashi, M; Sakabe, M; Yoshimoto, K | 1 |
| HAND, HA; MADDEN, RJ; SMITH, PK | 1 |
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| Cunningham, E | 1 |
| Bathaie, SZ; Moosavi-Movahedi, AA; Nikfarjam, L; Rahmanpour, R | 1 |
| ERCOLI, N; LEWIS, MN | 1 |
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| HIGLEY, CS | 1 |
| Blagbrough, IS; Elmasry, MS; Kheir, AA; Rogers, PJ; Rowan, MG; Saleh, HM | 1 |
| Dennis, M; Hamilton, B; Johnston, M; O'Carroll, R; Sudlow, C; Whittaker, J | 1 |
| Bowling, MR; Glisson, JK; Vesa, TS | 1 |
| Castillo, S; Díaz-Mula, HM; Guillén, F; Martínez-Romero, D; Serrano, M; Valero, D; Zapata, PJ | 1 |
| Borja, J; García-Rafanell, J | 1 |
| Huang, YN; Wang, W; Wu, LM; Ye, SD; Zhou, KQ | 1 |
| Khaidakov, M; Mehta, JL; Mitra, S | 1 |
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| Cefali, G; Gilmer, JF; Harmon, S; Jones, M; Kerins, DM; Ledwidge, MT; O'Connell, D; Ryan, F | 1 |
| Dueñas-Laita, A; Nogué-Xarau, S | 1 |
| Chevtzoff, C; Fullerton, MD; Green, KA; Hardie, DG; Hawley, SA; Kemp, BE; Mustard, KJ; Peggie, MW; Ross, FA; Sakamoto, K; Schertzer, JD; Steinberg, GR; Walker, KJ; Zibrova, D | 1 |
| Acciarresi, M; Caso, V; Paciaroni, M; Pezzella, FR; Santalucia, P | 1 |
| Croce, K; Gottschall, C; Manfroi, C; Manica, A; Marchini, JF; Rodrigues, LH; Sarmento-Leite, R | 1 |
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| Braga, AL; Canto, RF; Chagas, PM; da Luz, SC; Nogueira, CW; Oliveira, CE; Rosa, SG; Sari, MH | 1 |
| Alvarez-Sabín, J; Maisterra, O; Quintana, M; Santamarina, E | 1 |
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| Au, M; Gupta, MK; Hoffbauer, S; Nayan, S; Sommer, DD; Sowerby, LJ | 1 |
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| Calvello, R; Cianciulli, A; De Nuccio, F; La Pesa, V; Lofrumento, DD; Panaro, MA; Panella, A; Perrone, MG; Scilimati, A; Vitale, P | 1 |
| Chi, YC; Lai, CL; Lee, SL; Lee, YP; Liu, CM; Wu, ML; Yin, SJ | 1 |
| Cheretaev, IV; Gamma, TV; Khusainov, DR; Kolotilova, OI; Koreniuk, I; Nozdrachev, AD | 1 |
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77 review(s) available for aspirin and salicylates
| Article | Year |
|---|---|
The biochemical pathology of aspirin-induced gastric damage.
Topics: Age Factors; Alcohol Drinking; Animals; Anti-Inflammatory Agents; Ascorbic Acid Deficiency; Aspirin; Blood Group Antigens; Female; Food; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Hydrogen-Ion Concentration; Male; Nutritional Physiological Phenomena; Particle Size; Permeability; Prostaglandins; Regional Blood Flow; Salicylates; Sex Factors; Stomach Diseases; Stomach Ulcer; Structure-Activity Relationship | 1975 |
[Lysosomes, cyclic nucleotides and retinal degeneration].
Topics: Animals; Aspirin; Cortisone; Cyclic AMP; Cyclic GMP; Darkness; DNA; Lysosomes; Mice; Nucleotides, Cyclic; Rats; Rats, Inbred Strains; Retina; Retinal Degeneration; Salicylates; Species Specificity | 1978 |
Aspirin and prostaglandins: some recent developments.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Cyclooxygenase Inhibitors; Humans; Rheumatic Diseases; Salicylates | 1978 |
[Interactions of salicylates and other nonsteroid anti-inflammatory agents].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Drug Antagonism; Drug Interactions; Fenoprofen; Humans; Indomethacin; Phenylbutazone; Rats; Salicylates | 1977 |
Harmful effects of "aspirin compounds".
Topics: Acid-Base Equilibrium; Aspirin; Blood Coagulation; Blood Platelets; Carbon Dioxide; Digestive System; Ear, Inner; Fever; Gastric Mucosa; Gastrointestinal Hemorrhage; Homeostasis; Humans; Kidney; Kidney Papillary Necrosis; Phenacetin; Salicylates | 1977 |
On the use of blockers of prostaglandin synthesis in the control of labor.
Topics: Animals; Aspirin; Clinical Trials as Topic; Female; Fetal Death; Fetus; Hemodynamics; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Prostaglandin Antagonists; Salicylates; Sheep | 1978 |
Hematologic perturbations associated with salicylate.
Topics: Aspirin; Blood Platelets; Gastrointestinal Hemorrhage; Hematologic Diseases; Hematopoietic System; Hemolysis; Hemostasis; Humans; Leukocytes; Salicylates | 1979 |
Analgesics and the stomach.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Indomethacin; Male; Oxyphenbutazone; Peptic Ulcer; Phenylbutazone; Rheumatic Diseases; Salicylates; Stomach Diseases; Stomach Ulcer | 1976 |
Clinical pharmacology of acetylsalicylic acid.
Topics: Absorption; Aspirin; Blood Platelets; Digestive System; Drug Combinations; Drug Hypersensitivity; Hemostasis; Humans; Kidney; Probenecid; Protein Binding; Salicylates; Spironolactone; Thrombosis; Xylose | 1976 |
Aspirin, salicylates, and nonsteroidal anti-inflammatory drugs: new class labeling and medical practice.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Labeling; Gastrointestinal Diseases; Humans; Salicylates; United States; United States Food and Drug Administration | 1991 |
Aspirin versus the non-acetylated salicylates.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diflunisal; Humans; Rheumatic Diseases; Salicylates | 1990 |
Gastroduodenal mucosal damage with salsalate versus aspirin: results of experimental models and endoscopic studies in humans.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Duodenum; Endoscopy; Gastric Mucosa; Humans; Intestinal Mucosa; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Salicylates | 1990 |
Synthesis, properties and prodrug potential of 2-methyl-2-oxy- and 2-methyl-2-thio-4H-1,3-benzodioxin-4-ones.
Topics: Animals; Aspirin; Benzyl Alcohols; Dioxins; Hydrolysis; Models, Molecular; Molecular Structure; Prodrugs; Salicylates; Salicylic Acid | 1989 |
Drug interactions involving aspirin (acetylsalicylic acid) and salicylic acid.
Topics: Antacids; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Aspirin; Charcoal; Contraceptive Agents; Drug Interactions; Glucocorticoids; Histamine H2 Antagonists; Humans; Salicylates; Salicylic Acid | 1989 |
Non-aspirin salicylates: conversion factors for estimating aspirin equivalency.
Topics: Aspirin; Salicylates; Therapeutic Equivalency | 1989 |
Non-steroidal and analgesic therapy in the elderly.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Diclofenac; Drug Hypersensitivity; Gastrointestinal Diseases; Hematologic Diseases; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Diseases; Kinetics; Naproxen; Phenylbutazone; Piroxicam; Salicylates; Thiazines | 1986 |
Pharmacology of platelet inhibition in humans: implications of the salicylate-aspirin interaction.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Blood Vessels; Cyclooxygenase Inhibitors; Drug Interactions; Female; Humans; Kinetics; Leukocytes; Male; Platelet Aggregation; Salicylates; Salicylic Acid; Superoxides; Thrombosis | 1985 |
Salicylates in the treatment of arthritic disease. How safe and effective?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Cell Aggregation; Gastrointestinal Diseases; Humans; Neutrophils; Prostaglandins; Salicylates | 1988 |
Cutaneous reactions to nonsteroidal anti-inflammatory drugs. A review.
Topics: Acetates; Anti-Inflammatory Agents; Aspirin; Drug Eruptions; Humans; Ibuprofen; Indomethacin; ortho-Aminobenzoates; Piroxicam; Propionates; Pruritus; Pyrazoles; Pyrazolones; Salicylates; Skin; Skin Diseases; Stevens-Johnson Syndrome; Thiazines | 1985 |
Gastroduodenal mucosal defence mechanisms and the action of non-steroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bicarbonates; Duodenum; Gastric Mucosa; Intestinal Mucosa; Salicylates; Salicylic Acid | 1987 |
Salicylates in Kawasaki disease--a review of clinical pharmacokinetics and efficacy.
Topics: Aspirin; Biological Availability; Blood Proteins; Child; Child, Preschool; Clinical Trials as Topic; Humans; Liver; Mucocutaneous Lymph Node Syndrome; Protein Binding; Salicylates | 1987 |
Current concepts in the treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin; Drug Interactions; Gold; Humans; Immunosuppressive Agents; Penicillamine; Salicylates | 1986 |
Aspirin and related derivatives of salicylic acid.
Topics: Aspirin; Humans; Kinetics; Salicylates | 1986 |
Clinical pharmacology of pediatric antipyretic drugs.
Topics: Acetaminophen; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Choline; Diclofenac; Drug Combinations; Humans; Ibuprofen; Kinetics; Naproxen; Salicylates | 1985 |
Drug interactions with methotrexate.
Topics: Absorption; Anti-Bacterial Agents; Arthritis, Rheumatoid; Aspirin; Biological Transport; Cell Membrane; Cisplatin; Dose-Response Relationship, Drug; Drug Interactions; Folic Acid; Humans; Kidney Tubules; Methotrexate; Probenecid; Protein Binding; Salicylates; Serum Albumin; Sulfamethoxazole; Sulfonamides; Tissue Distribution | 1985 |
Treatment and prevention of rheumatic fever and rheumatic heart disease.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Aspirin; Child; Cortisone; Digitalis Glycosides; Electrocardiography; Heart Failure; Humans; Injections, Intramuscular; Penicillin G Benzathine; Physical Exertion; Rheumatic Fever; Rheumatic Heart Disease; Salicylates; Streptococcal Infections; Streptococcus; Virulence | 1964 |
[Effect of some antirheumatic agents on the gastric mucous membrane].
Topics: Adrenocorticotropic Hormone; Aged; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Dogs; Drug Hypersensitivity; Duodenal Ulcer; Esophageal Diseases; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Glucocorticoids; Humans; Hydrocortisone; Indomethacin; Intestinal Mucosa; Osteoarthritis; Penicillins; Phenylbutazone; Prednisolone; Rats; Rheumatic Diseases; Salicylates; Sodium Salicylate; Stomach Diseases; Stomach Ulcer; Streptomycin | 1971 |
The treatment of teething in infants. A review.
Topics: Acetaminophen; Alcohols; Aspirin; Feeding and Eating Disorders; Gels; Humans; Hypnotics and Sedatives; Infant; Lidocaine; Mouth Mucosa; Salicylates; Sleep Wake Disorders; Tooth Eruption | 1972 |
Unravelling analgesic nephropathy.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Carcinoma, Transitional Cell; Female; Humans; Kidney Neoplasms; Kidney Papillary Necrosis; Male; Microsomes, Liver; Phenacetin; Rats; Salicylates; Spermatogenesis; Substance-Related Disorders | 1972 |
Potential environmental chemical hazards. I. Drugs.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Analgesics; Animals; Aspirin; Carcinogens; Drug-Related Side Effects and Adverse Reactions; Hexachlorophene; Humans; Hydrazines; Isoniazid; Phenacetin; Phenylbutazone; Phenytoin; Procarbazine; Salicylates | 1972 |
Nonsteroidal anti-inflammatory drugs (first of two parts).
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents; Aspirin; Bone Marrow; Drug Hypersensitivity; Gastric Mucosa; Gout; Humans; Phenacetin; Phenylbutazone; Rheumatic Diseases; Salicylates; Stomach Diseases | 1974 |
The role of patelloplasty and patellectomy in the arthritic knee.
Topics: Arthroplasty; Aspirin; Cathepsins; Debridement; Humans; Joint Dislocations; Joint Prosthesis; Knee; Osteoarthritis; Patella; Salicylates; Synovitis | 1974 |
Management of acute poisoning with activated charcoal.
Topics: Analgesics; Animals; Antidepressive Agents; Aspirin; Barbiturates; Charcoal; Child; Child, Preschool; Dextropropoxyphene; Digestive System; Dogs; Gastrointestinal Motility; Humans; Hypnotics and Sedatives; Infant; Intestinal Absorption; Poisoning; Rats; Salicylates; Time Factors; Tranquilizing Agents | 1974 |
[Allergic reactions in asthmatics caused by salicylates and food additives].
Topics: Aspirin; Asthma; Drug Hypersensitivity; Food Additives; Food Preservatives; Humans; Salicylates | 1974 |
[Filling of drugs into gelatine capsules in pharmacies].
Topics: Acetanilides; Antipyrine; Aspirin; Bicarbonates; Bismuth; Caffeine; Capsules; Codeine; Dosage Forms; Methods; Nitrates; Pharmacies; Phosphates; Quinine; Salicylates; Sodium; Starch; Sulfates; Technology, Pharmaceutical | 1969 |
Cutaneous responses to aspirin and its derivatives.
Topics: Aspirin; Erythema; Erythema Multiforme; Humans; Psoriasis; Purpura; Salicylates; Skin Diseases; Urticaria | 1970 |
Determination of the decomposition of aspirin.
Topics: Aspirin; Chemical Phenomena; Chemistry; Chemistry, Pharmaceutical; Chromatography; Drug Stability; Hydrogen-Ion Concentration; Iron; Kinetics; Mathematics; Methods; Pharmaceutic Aids; Powders; Salicylates; Spectrophotometry; Tablets; Temperature; Ultraviolet Rays | 1970 |
Drugs and bilirubin.
Topics: Adult; Animals; Aspirin; Bile Acids and Salts; Bilirubin; Biological Transport; Biotransformation; Endoplasmic Reticulum; Enzyme Induction; Humans; Hyperbilirubinemia, Hereditary; Infant, Newborn; Jaundice, Neonatal; Liver; Phenobarbital; Protein Binding; Rats; Salicylates; Transferases | 1971 |
[Analgesic drugs for peroral use].
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Headache; Humans; Ischemia; Kinetics; Neoplasms; Neuralgia; Phenacetin; Phenylbutazone; Salicylates; Time Factors; Wounds and Injuries | 1970 |
[Gastrointestinal bleeding following ingestion of salicylates].
Topics: Animals; Anticoagulants; Ascorbic Acid Deficiency; Aspirin; Cats; Gastric Juice; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Hemorrhagic Disorders; Histamine; Humans; Occult Blood; Pepsin A; Rats; Salicylates; Time Factors; Vagotomy; Vagus Nerve; von Willebrand Diseases | 1971 |
Treatment of salicylate poisoning.
Topics: Acetaminophen; Acid-Base Equilibrium; Acidosis; Acute Kidney Injury; Alkalosis, Respiratory; Aspirin; Calcium; Coma; Dehydration; Fever; Gastric Lavage; Hemorrhage; Humans; Hydrogen-Ion Concentration; Infusions, Parenteral; Poisoning; Salicylamides; Salicylates; Seizures; Tetany; Vomiting | 1971 |
The formulation of aspirin.
Topics: Administration, Oral; Aspirin; Biopharmaceutics; Dosage Forms; Drug Compounding; Evaluation Studies as Topic; Gastrointestinal Motility; Half-Life; Hemorrhage; Humans; Intestinal Absorption; Kinetics; Salicylates; Time Factors | 1971 |
A pharmacological analysis of aspirin.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Blood Chemical Analysis; Bradykinin; Bronchi; Cats; Chemical Phenomena; Chemistry; Constriction; Dogs; Enzyme Inhibitors; Epithelium; Exudates and Transudates; Gastric Mucosa; Guinea Pigs; Haplorhini; Hemostasis; Histamine; Inflammation; Kidney Tubules; Mice; Muscle, Smooth; Muscles; Neurons; Pain; Peptides; Rabbits; Rats; Salicylates | 1969 |
Salicylate metabolism in man.
Topics: Acylation; Adolescent; Aminopyrine; Animals; Antipyrine; Aspirin; Biotransformation; Brain; Dogs; Ephedrine; Female; Gastric Mucosa; Glucuronates; Haplorhini; Humans; Hydrogen-Ion Concentration; Hydrolysis; Intestinal Absorption; Kidney; Kinetics; Liver; Male; Placenta; Pregnancy; Quinine; Rats; Rheumatic Heart Disease; Salicylamides; Salicylates; Secobarbital; Thiopental | 1971 |
Aspirin in the treatment of juvenile arthritis.
Topics: Arthritis, Juvenile; Aspirin; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Humans; Liver Diseases; Protein Binding; Salicylates; Serum Albumin | 1983 |
Aspirin: plasma concentration and effects.
Topics: Animals; Aspirin; Fibrinolytic Agents; Half-Life; Humans; Salicylates; Salicylic Acid | 1983 |
Review of the comparative analgesic efficacy of salicylates, acetaminophen, and pyrazolones.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Aspirin; Codeine; Dose-Response Relationship, Drug; Drug Combinations; Humans; Pyrazoles; Salicylates | 1983 |
Interaction of salicylate and other non-steroidal anti-inflammatory drugs with aspirin on platelet and vascular cyclo-oxygenase activity.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Blood Vessels; Cyclooxygenase Inhibitors; Humans; Salicylates | 1983 |
Mechanisms of action: aspirin.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Endothelium; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Salicylates; Salicylic Acid; Thromboxanes | 1983 |
Tissue-selective inhibition of prostaglandin and thromboxane synthesis in man: investigative and therapeutic implications.
Topics: Antithrombins; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Gastric Mucosa; Humans; Kidney; Kinetics; Oxidoreductases; Prostaglandin Antagonists; Salicylates; Sulindac; Thromboxane-A Synthase | 1984 |
Drug therapy: nonsteroidal antiinflammatory drugs (first of two parts).
Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Child; Drug Tolerance; Female; Gastric Mucosa; Gastritis; Humans; Indomethacin; Infant, Newborn; Inflammation; Kidney; Kinetics; Liver; Maternal-Fetal Exchange; Pregnancy; Prostaglandins; Salicylates; Stomach Ulcer | 1980 |
Hepatotoxicity of mild analgesics.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Chemical and Drug Induced Liver Injury; Child; Humans; Phenacetin; Phenylbutazone; Salicylates | 1980 |
Mechanisms in the development of analgesic nephropathy.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Synergism; Humans; Kidney; Kidney Diseases; Kidney Papillary Necrosis; Phenacetin; Salicylates; Tissue Distribution | 1980 |
[Therapy of acute salicylate poisoning].
Topics: Aspirin; Charcoal; Coma; Fatal Outcome; Female; Fever; Gastric Lavage; Glycine; Hemoperfusion; Humans; Middle Aged; Poisoning; Renal Dialysis; Salicylates; Sodium Bicarbonate | 1993 |
[Antiphlogistic effect of salicylic acid and its derivatives].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Humans; Inflammation; Salicylates; Salicylic Acid | 1993 |
Ototoxicity associated with salicylates. A brief review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Hearing Loss; Humans; Salicylates; Tinnitus | 1993 |
[Salicylic acid].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Salicylates | 1995 |
[Percutaneous penetration of drugs--application in physical therapy].
Topics: Administration, Oral; Administration, Topical; Animals; Aspirin; Dogs; Humans; Niacin; Physical Therapy Modalities; Salicylates; Skin Absorption | 1997 |
Triflusal.
Topics: Adult; Angina Pectoris; Animals; Aspirin; Carotid Stenosis; Humans; In Vitro Techniques; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Postoperative Complications; Pulmonary Embolism; Randomized Controlled Trials as Topic; Salicylates; Thrombophlebitis | 1998 |
[The risk of hemorrhage in long-term use of aspirin and triflusal].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cerebral Infarction; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Salicylates; Sex Factors; Time Factors | 1998 |
[Effects of salicylates on the physiological function of cochlea].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cochlea; Cochlear Microphonic Potentials; Humans; Otoacoustic Emissions, Spontaneous; Salicylates | 1998 |
Salicylates and vascular smooth muscle cell proliferation: molecular mechanisms for cell cycle arrest.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Cycle; Cell Division; Down-Regulation; Humans; Muscle, Smooth, Vascular; NF-kappa B; Salicylates | 2001 |
New steroids and new salicylates in inflammatory bowel disease: a critical appraisal.
Topics: Acute Disease; Aspirin; Beclomethasone; Budesonide; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Combination; Glucocorticoids; Humans; Inflammatory Bowel Diseases; Prednisolone; Randomized Controlled Trials as Topic; Salicylates; Sulfasalazine | 2002 |
[THE CURRENT TREATMENT OF ACUTE ARTICULAR RHEUMATISM].
Topics: Aspirin; Convalescence; Endocarditis; Endocarditis, Bacterial; Humans; Immunotherapy, Active; Penicillins; Phenylbutazone; Rheumatic Fever; Salicylates; Sulfanilamide; Sulfanilamides; Sulfonamides | 1964 |
Adverse effects and drug interactions of antithrombotic agents used in prevention of ischaemic stroke.
Topics: Anticoagulants; Aspirin; Clopidogrel; Dipyridamole; Drug Interactions; Drug Therapy, Combination; Humans; Platelet Aggregation Inhibitors; Salicylates; Stroke; Ticlopidine; Warfarin | 2005 |
Triflusal for preventing serious vascular events in people at high risk.
Topics: Aspirin; Humans; Ischemic Attack, Transient; Myocardial Infarction; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Salicylates; Stroke | 2005 |
Review of antiplatelet therapy in secondary prevention of cerebrovascular events: a need for direct comparisons between antiplatelet agents.
Topics: Aspirin; Clopidogrel; Dipyridamole; Humans; Platelet Aggregation Inhibitors; Recurrence; Salicylates; Stroke; Ticlopidine | 2005 |
[Acute salicylate poisoning].
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Diagnosis, Differential; Drug Interactions; Drug Overdose; Fixatives; Humans; Ointments; Poisoning; Prognosis; Pulmonary Edema; Salicylates; Time Factors | 2006 |
From willow bark to peptides: the ever widening spectrum of NF-kappaB inhibitors.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Glucocorticoids; Humans; Inflammation; NF-kappa B; Peptides; Plant Bark; Plant Extracts; Plant Preparations; Salicylates; Salix; Signal Transduction | 2006 |
Emergency department management of the salicylate-poisoned patient.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Overdose; Emergency Service, Hospital; Humans; Renal Dialysis; Resuscitation; Salicylates | 2007 |
Current management of salicylate-induced pulmonary edema.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Pulmonary Edema; Salicylates | 2011 |
Antiplatelet treatment in primary and secondary stroke prevention in women.
Topics: Aspirin; Clopidogrel; Dipyridamole; Drug Therapy, Combination; Female; Humans; Naphthalenes; Platelet Aggregation Inhibitors; Primary Prevention; Propionates; Salicylates; Secondary Prevention; Sex Factors; Stroke; Ticlopidine | 2012 |
Aspirin and salicylate in respiratory disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; Desensitization, Immunologic; Humans; Salicylates | 2013 |
Targeting epigenetic mechanisms and microRNAs by aspirin and other non steroidal anti-inflammatory agents--implications for cancer treatment and chemoprevention.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Neoplasms; Salicylates | 2014 |
Interaction of Salicylates and the Other Nonsteroidal Anti-Inflammatory Agents With Breast Cancer Endocrine Treatment: Systematic Review.
Topics: Androstadienes; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Aspirin; Breast Neoplasms; Celecoxib; Drug Synergism; Female; Humans; Salicylates; Tamoxifen | 2015 |
Concentration-Response Relationship of Hearing Impairment Caused by Quinine and Salicylate: Pharmacological Similarities but Different Molecular Mechanisms.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Aspirin; Dose-Response Relationship, Drug; Hair Cells, Auditory, Outer; Hearing Loss, Sensorineural; Humans; Mechanotransduction, Cellular; Molecular Structure; Quinine; Salicylates; Severity of Illness Index; Tinnitus | 2017 |
Aspirin-exacerbated respiratory disease and current treatment modalities.
Topics: Algorithms; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Aspirin; Asthma; Desensitization, Immunologic; Diet; Humans; Immunotherapy; Leukotriene Antagonists; Nasal Polyps; Omalizumab; Rhinitis; Salicylates; Sinusitis | 2017 |
151 trial(s) available for aspirin and salicylates
| Article | Year |
|---|---|
Evaluation of analgesic action and efficacy of antirheumatic drugs. Study of 10 drugs in 684 patients with rheumatoid arthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Mefenamic Acid; Pain; Phenylacetates; Placebos; Prednisone; Salicylates | 1976 |
Acute acetylsalicylic acid poisoning: treatment with forced alkaline diuresis and diuretics.
Topics: Acid-Base Equilibrium; Adolescent; Adult; Aspirin; Barbiturates; Blood Gas Analysis; Bumetanide; Child, Preschool; Clinical Trials as Topic; Diuresis; Diuretics; Female; Furosemide; Gastric Lavage; Humans; Hydrogen-Ion Concentration; Male; Potassium; Salicylates | 1977 |
Aspirin, paracetamol, diflunisal, and gastrointestinal blood-loss.
Topics: Acetaminophen; Aspirin; Gastrointestinal Hemorrhage; Humans; Salicylates | 1979 |
Diflunisal, aspirin, and gastric mucosa.
Topics: Aspirin; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Gastric Mucosa; Gastritis; Humans; Peptic Ulcer Hemorrhage; Salicylates | 1979 |
Diflunisal, a new analgesic, in the treatment of postoperative pain following removal of impacted mandibular third molars.
Topics: Administration, Oral; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middle Aged; Pain, Postoperative; Placebos; Salicylates; Tooth, Impacted | 1979 |
Fecal blood loss and plasma salicylate study of salicylsalicylic acid and aspirin.
Topics: Adult; Aspirin; Chromium Radioisotopes; Female; Gastrointestinal Hemorrhage; Humans; Liver; Male; Placebos; Salicylates; Time Factors | 1979 |
Diflunisal: efficacy in postoperative pain.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Fluorobenzenes; Humans; Male; Middle Aged; Pain, Postoperative; Placebos; Salicylates; Time Factors | 1977 |
Diflunisal: six-month experience in osteoarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Drug Evaluation; Fluorobenzenes; Humans; Ibuprofen; Osteoarthritis; Patient Dropouts; Salicylates; Time Factors | 1977 |
Gastric ulcer, aspirin esterase and aspirin.
Topics: Aspirin; Clinical Trials as Topic; Esterases; Ethanol; Female; Gastric Mucosa; Humans; Male; Methods; Salicylates; Stomach Ulcer | 1977 |
Fendosal and aspirin in postpartum uterine pain.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Indoles; Pain; Postpartum Period; Pregnancy; Salicylates; Time Factors | 1978 |
On the use of blockers of prostaglandin synthesis in the control of labor.
Topics: Animals; Aspirin; Clinical Trials as Topic; Female; Fetal Death; Fetus; Hemodynamics; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Prostaglandin Antagonists; Salicylates; Sheep | 1978 |
Gastrointestinal blood loss after diflunisal and after aspirin: effect of ethanol.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Ethanol; Gastrointestinal Hemorrhage; Humans; Male; Salicylates | 1978 |
A single dose study comparing the analgesic effects of diflunisal, acetylsalicylic acid, and placebo in pain following meniscectomy.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Menisci, Tibial; Pain, Postoperative; Placebos; Salicylates | 1978 |
The effects of enteric coating of aspirin tablets on occult gastrointestinal blood loss.
Topics: Aged; Aspirin; Biological Availability; Clinical Trials as Topic; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Occult Blood; Salicylates; Tablets, Enteric-Coated | 1977 |
Comparative study of salsalate and aspirin in osteoarthrosis of the hip or knee.
Topics: Acetaminophen; Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Hip Joint; Humans; Knee Joint; Male; Middle Aged; Occult Blood; Osteoarthritis; Salicylates | 1978 |
[Salicylate dosage for children with juvenile chronic arthritis].
Topics: Adolescent; Arthritis, Juvenile; Aspartate Aminotransferases; Aspirin; Capsules; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Humans; Salicylates; Tablets, Enteric-Coated | 1978 |
[Comparison of eterilate and acetylsalicylic acid in the treatment of cervicoarthrosis: double blind test].
Topics: Acetanilides; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Cervical Vertebrae; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Middle Aged; Salicylates | 1978 |
Relationship of plasma salicylate levels to pain relief with two different salicylates.
Topics: Analgesics; Aspirin; Biphenyl Compounds; Clinical Trials as Topic; Humans; Occult Blood; Osteoarthritis; Pain; Salicylates; Time Factors | 1978 |
Auditory changes associated with moderate blood salicylate levels.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Evaluation; Female; Hearing; Hearing Tests; Humans; Male; Middle Aged; Placebos; Salicylates | 1978 |
A clinical trial of diflunisal against aspirin in osteoarthritis.
Topics: Abdomen; Aspirin; Clinical Trials as Topic; Dizziness; Double-Blind Method; Drug Administration Schedule; Edema; Humans; Osteoarthritis; Pain; Salicylates; Time Factors | 1978 |
Diflunisal and aspirin: a comparison of efficacy and nephrotoxicity in osteoarthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Kidney Diseases; Male; Middle Aged; Osteoarthritis; Salicylates | 1979 |
Diflunisal -- a new analgesic.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Double-Blind Method; Family Practice; Female; Humans; Male; Pain; Salicylates | 1979 |
Clinical comparative evaluation of choline magnesium trisalicylate and acetylsalicylic acid in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Choline; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Salicylates | 1979 |
The aspirin-ibuprofen interaction in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Middle Aged; Salicylates; Time Factors | 1979 |
Plasma salicylate levels after soluble and effervescent aspirin.
Topics: Aspirin; Bicarbonates; Female; Humans; Male; Salicylates; Solutions; Tablets; Time Factors | 1979 |
Tienilic acid: pharmacokinetics, salicylate interaction and creatinine secretion studies.
Topics: Adult; Aspirin; Creatinine; Drug Interactions; Glycolates; Humans; Male; Natriuresis; Salicylates; Ticrynafen; Uric Acid | 1979 |
Enhanced absorption of salicylate from Safapyryn-Co tablets.
Topics: Acetaminophen; Adult; Aspirin; Codeine; Drug Combinations; Female; Humans; Intestinal Absorption; Salicylates; Time Factors | 1979 |
Reduction of absorption of digoxin, phenytoin and aspirin by activated charcoal in man.
Topics: Adult; Aspirin; Charcoal; Depression, Chemical; Digoxin; Female; Humans; Intestinal Absorption; Male; Phenytoin; Salicylates | 1978 |
Evaluation of five activated charcoal formulations for inhibition of aspirin absorption and palatability in man.
Topics: Absorption; Administration, Oral; Adsorption; Adult; Antidotes; Aspirin; Charcoal; Excipients; Female; Humans; Male; Mineral Oil; Salicylates; Taste; Time Factors | 1978 |
The bioavailability of enteric-coated acetylsalicylic acid: a comparison with buffered ASA in rheumatoid arthritis II.
Topics: Arthritis, Rheumatoid; Aspirin; Biological Availability; Buffers; Clinical Trials as Topic; Humans; Salicylates; Tablets, Enteric-Coated | 1976 |
Juvenile chronic polyarthritis: clinical sub-groups and response to medication.
Topics: Acetaminophen; Adolescent; Aspirin; Child; Female; Humans; Male; Phenylbutazone; Salicylates; Spondylitis, Ankylosing | 1977 |
Correlation of plateau serum salicylate level with rate of salicylate metabolism.
Topics: Administration, Oral; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Female; Humans; Injections, Intravenous; Male; Middle Aged; Salicylates; Time Factors | 1975 |
Pharmacokinetics and relative bioavailability of a new chewable, buffered acetylsalicylic acid tablet formulation in comparison to a conventional plain tablet.
Topics: Adolescent; Adult; Aspirin; Biological Availability; Humans; Male; Salicylates; Tablets | 1992 |
Multiple-dose charcoal and whole-bowel irrigation do not increase clearance of absorbed salicylate.
Topics: Administration, Oral; Adult; Aspirin; Charcoal; Female; Humans; Intestinal Absorption; Intestines; Male; Poisoning; Salicylates; Salicylic Acid; Therapeutic Irrigation | 1992 |
Central analgesic effects of acetylsalicylic acid in healthy men.
Topics: Adult; Analgesics; Arousal; Aspirin; Double-Blind Method; Electric Stimulation; Electrodes; Electroencephalography; Evoked Potentials, Auditory; Humans; Male; Reaction Time; Salicylates; Salicylic Acid | 1991 |
Aspirin-induced gastric mucosal damage: prevention by enteric-coating and relation to prostaglandin synthesis.
Topics: Adult; Aspirin; Dinoprostone; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Male; Salicylates; Stomach Diseases; Tablets, Enteric-Coated; Thromboxane B2 | 1991 |
Suppression of thromboxane A2 but not of systemic prostacyclin by controlled-release aspirin.
Topics: Adolescent; Adult; Aspirin; Blood Platelets; Bradykinin; Delayed-Action Preparations; Depression, Chemical; Drug Administration Schedule; Epoprostenol; Humans; Male; Middle Aged; Salicylates; Thromboxane A2 | 1991 |
Coagulation, fibrinolytic and platelet function in patients on long-term therapy with aspirin 300 mg or 1,200 mg daily compared with placebo.
Topics: Aged; Aged, 80 and over; Aspirin; Bleeding Time; Blood Coagulation; Dose-Response Relationship, Drug; Female; Fibrinolysis; Fibrinopeptide A; Humans; Male; Middle Aged; Placebos; Plasminogen Activators; Platelet Aggregation; Platelet Aggregation Inhibitors; Salicylates; Thromboembolism; Thromboxane B2; Time Factors | 1990 |
Salicylate pre-treatment attenuates intensity of bronchial and nasal symptoms precipitated by aspirin in aspirin-intolerant patients.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Spasm; Choline; Double-Blind Method; Drug Hypersensitivity; Drug Tolerance; Female; Humans; Male; Middle Aged; Nose; Salicylates | 1990 |
A double-blind crossover study to compare lysine acetyl salicylate (Aspergesic) with ibuprofen in the treatment of rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Double-Blind Method; Female; Humans; Ibuprofen; Lysine; Male; Randomized Controlled Trials as Topic; Salicylates | 1990 |
Does the acetyl group of aspirin contribute to the antiinflammatory efficacy of salicylic acid in the treatment of rheumatoid arthritis?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Double-Blind Method; Female; Humans; Male; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Salicylates | 1990 |
Choline magnesium trisalicylate in patients with aspirin-induced asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Choline; Double-Blind Method; Drug Hypersensitivity; Drug Tolerance; Female; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Respiratory Function Tests; Salicylates; Single-Blind Method | 1990 |
A comparison of choline magnesium trisalicylate and acetylsalicylic acid in patients with rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Choline; Disability Evaluation; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Pain Measurement; Randomized Controlled Trials as Topic; Salicylates | 1990 |
Comparison of salsalate and aspirin on mucosal injury and gastroduodenal mucosal prostaglandins.
Topics: Adult; Aged; Aspirin; Dinoprost; Dinoprostone; Gastric Mucosa; Humans; Intestinal Mucosa; Middle Aged; Prostaglandins; Salicylates | 1990 |
Salsalate cross-sensitivity in aspirin-sensitive patients with asthma.
Topics: Acetaminophen; Administration, Oral; Aspirin; Asthma; Double-Blind Method; Drug Hypersensitivity; Forced Expiratory Volume; Humans; Hydrocortisone; Salicylates; Statistics as Topic | 1990 |
Concentration-response relationships for salicylate-induced ototoxicity in normal volunteers.
Topics: Adult; Aspirin; Double-Blind Method; Hearing Disorders; Hearing Tests; Humans; Male; Salicylates | 1989 |
Prevention of aortocoronary vein-graft attrition with low-dose aspirin and triflusal, both associated with dipyridamole: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Coronary Artery Bypass; Dipyridamole; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Patient Compliance; Prospective Studies; Random Allocation; Salicylates; Vascular Patency | 1989 |
Does the acetyl group of aspirin contribute to the antiinflammatory efficacy of salicylic acid in the treatment of rheumatoid arthritis? The Multicenter Salsalate/Aspirin Comparison Study Group.
Topics: Acetylation; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Double-Blind Method; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Random Allocation; Salicylates; Therapeutic Equivalency | 1989 |
Large surface area activated charcoal and the inhibition of aspirin absorption.
Topics: Absorption; Adult; Aspirin; Charcoal; Double-Blind Method; Gastric Mucosa; Humans; Intestinal Absorption; Male; Random Allocation; Salicylates; Salicylic Acid; Surface Properties | 1989 |
Comparison of the effect of aspirin and choline magnesium trisalicylate on thromboxane biosynthesis in human platelets: role of the acetyl moiety.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Blood Platelets; Choline; Double-Blind Method; Female; Humans; Male; Random Allocation; Salicylates; Thromboxane B2; Thromboxanes | 1989 |
Salicylsalicylic acid causes less gastroduodenal mucosal damage than enteric-coated aspirin. An endoscopic comparison.
Topics: Adolescent; Adult; Aspirin; Duodenum; Endoscopy; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Random Allocation; Salicylates; Tablets, Enteric-Coated | 1989 |
Effects of salicylic and acetylsalicylic acid alone and in combination on platelet aggregation and prostanoid synthesis in man.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Dinoprostone; Diuresis; Drug Interactions; Electrolytes; Humans; Platelet Aggregation; Prostaglandins; Prostaglandins E; Random Allocation; Salicylates; Thromboxane B2 | 1986 |
Salicylate ototoxicity in patients with rheumatoid arthritis: a controlled study.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Aspirin; Audiometry; Clinical Trials as Topic; Hearing Loss, Sensorineural; Humans; Middle Aged; Salicylates; Tinnitus | 1988 |
Measurement of the analgesic effects of aspirin with a new experimental algesimetric procedure.
Topics: Analgesia; Analysis of Variance; Aspirin; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Pain; Pain Measurement; Salicylates; Salicylic Acid | 1988 |
[Clinical trial of a new non-steroidal analgesic (diflunisal) in oral surgery].
Topics: Adult; Aspirin; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Humans; Male; Middle Aged; Pain, Postoperative; Random Allocation; Salicylates; Surgery, Oral | 1987 |
Salicylates in Kawasaki disease--a review of clinical pharmacokinetics and efficacy.
Topics: Aspirin; Biological Availability; Blood Proteins; Child; Child, Preschool; Clinical Trials as Topic; Humans; Liver; Mucocutaneous Lymph Node Syndrome; Protein Binding; Salicylates | 1987 |
Therapeutic potential of choline magnesium trisalicylate as an alternative to aspirin for patients with bleeding tendencies.
Topics: Adolescent; Adult; Aspirin; Choline; Clinical Trials as Topic; Hemorrhage; Humans; In Vitro Techniques; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Salicylates | 1987 |
Comparative efficacy study of chewable aspirin and acetaminophen in the antipyresis of children.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Temperature; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Salicylates; Salicylic Acid; Time Factors | 1986 |
[Use of diflunisal in postoperative pain of the oral cavity].
Topics: Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Humans; Middle Aged; Mouth; Pain, Postoperative; Random Allocation; Salicylates; Time Factors | 1986 |
Comparison of diflunisal and aspirin in long-term treatment of patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Random Allocation; Salicylates; Time Factors | 1986 |
Comparison of diflunisal and an aspirin-codeine combination in the management of patients having one-visit endodontic therapy.
Topics: Adolescent; Adult; Aged; Aspirin; Codeine; Diflunisal; Drug Combinations; Female; Humans; Male; Middle Aged; Pain, Postoperative; Prospective Studies; Random Allocation; Root Canal Therapy; Salicylates; Time Factors | 1987 |
Comparative bioavailability of aspirin from buffered, enteric-coated and plain preparations.
Topics: Administration, Oral; Adult; Aspirin; Biological Availability; Buffers; Humans; Kinetics; Male; Random Allocation; Salicylates; Salicylic Acid; Tablets; Tablets, Enteric-Coated | 1986 |
Evaluation of a potential drug interaction between sucralfate and aspirin.
Topics: Adsorption; Adult; Aluminum; Aspirin; Drug Combinations; Drug Interactions; Gastric Mucosa; Hippurates; Humans; Kinetics; Male; Random Allocation; Salicylates; Salicylic Acid; Sucralfate | 1986 |
Acetylsalicylic acid and juvenile rheumatoid Arthritis. Effect of dosage interval on the serum salicylic acid level.
Topics: Adolescent; Arthritis, Juvenile; Aspirin; Child; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Male; Salicylates | 1985 |
[Double blind comparison between imidazole-2-hydroxybenzoate and acetylsalicylic acid in the treatment of articular pain].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Imidazoles; Joint Diseases; Male; Middle Aged; Pain; Random Allocation; Salicylates | 1985 |
Protection against aspirin-induced antral and duodenal damage with enprostil. A double-blind endoscopic study.
Topics: Adolescent; Adult; Aspirin; Drug Evaluation; Duodenum; Enprostil; Female; Gastric Fundus; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Prostaglandins E, Synthetic; Pyloric Antrum; Random Allocation; Salicylates; Salicylic Acid | 1985 |
[Skin reactions in connection with systemic administration of drugs].
Topics: Anti-Bacterial Agents; Antitubercular Agents; Aspirin; Clinical Trials as Topic; Coloring Agents; Contraceptives, Oral; Drug Eruptions; Eczema; Erythema Multiforme; Humans; Placebos; Salicylates; Skin; Urticaria | 1973 |
Comparison of aspirin and benorylate in the treatment of rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Analgesics; Aniline Compounds; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Movement; Pain; Phenols; Physical Examination; Salicylates; Tinnitus | 1972 |
Double-blind comparison of aspirin and 4-(acetamido) phenyl-2-acetoxy-benzoate (benorylate) in rheumatoid arthritis.
Topics: Acetanilides; Acetates; Analgesics; Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Clinical Trials as Topic; Female; Humans; Inflammation; Male; Middle Aged; Pain; Salicylates | 1973 |
Toxicity of benorylate.
Topics: Acetanilides; Acetates; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Humans; Salicylates; Tinnitus | 1973 |
Some observations on blood level data following oral administration of aspirin as tablets and capsules.
Topics: Administration, Oral; Aspirin; Capsules; Clinical Trials as Topic; Humans; Kinetics; Regression Analysis; Salicylates; Tablets; Time Factors | 1973 |
Treatment of pain in hemophilia. Effect of drugs on bleeding time.
Topics: Administration, Oral; Analgesics; Aspirin; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Drug Evaluation; Hemophilia A; Humans; Pain; Pentazocine; Prednisone; Salicylates | 1974 |
Effect of concurrent administration of aspirin and indomethacin on serum concentrations.
Topics: Administration, Oral; Adult; Analysis of Variance; Aspirin; Chromatography, Thin Layer; Clinical Trials as Topic; Drug Interactions; Drug Therapy, Combination; Humans; Indomethacin; Methods; Salicylates; Spectrometry, Fluorescence; Suppositories; Time Factors | 1974 |
Effect of naproxen and of aspirin on bleeding time and platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Analysis of Variance; Aspirin; Blood Cell Count; Blood Coagulation; Clinical Trials as Topic; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Naphthalenes; Occult Blood; Placebos; Platelet Adhesiveness; Propionates; Prothrombin Time; Salicylates; Time Factors | 1974 |
[Do parenterally administered anti-prostaglandins have an action on the ocular pressure?].
Topics: Acetazolamide; Aspirin; Clinical Trials as Topic; Humans; Indomethacin; Intraocular Pressure; Placebos; Prostaglandin Antagonists; Salicylates; Sodium Salicylate | 1972 |
Clinical evaluation of the analgesic effect of magnesium salicylate.
Topics: Adult; Aged; Arthritis; Aspirin; Clinical Trials as Topic; Female; Humans; Magnesium; Male; Middle Aged; Salicylates | 1967 |
A clinical trial of flufenamic acid in the treatment of rheumatoid arthritis.
Topics: Abdomen, Acute; Acetaminophen; Aluminum; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspartate Aminotransferases; Aspirin; Clinical Trials as Topic; Codeine; Diarrhea; Female; Flufenamic Acid; Fluorine; Humans; Mefenamic Acid; ortho-Aminobenzoates; Phenylbutazone; Phosphates; Placebos; Salicylates; Stomatitis | 1966 |
Absence of gastrointestinal bleeding following administration of salicylsalicylic acid.
Topics: Adult; Aspirin; Chromium Isotopes; Clinical Trials as Topic; Feces; Female; Gastrointestinal Hemorrhage; Humans; Male; Placebos; Salicylates | 1969 |
Evaluation in man of fenclozic acid (I.C.I. 54,450: Myalex), a new anti-inflamatory agent. II. Clinical trial in patients with rheumatoid arthritis.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspartate Aminotransferases; Aspirin; Clinical Trials as Topic; Female; Hand; Humans; Isocitrate Dehydrogenase; Male; Placebos; Salicylates; Thiazoles | 1969 |
Plasma salicylate levels in rheumatoid arthritis produced by four different salicylate preparations.
Topics: Aluminum; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Delayed-Action Preparations; Humans; Oxides; Polymers; Salicylates; Sodium; Tablets, Enteric-Coated | 1970 |
Sustained release aspirin.
Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Deafness; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Salicylates; Time Factors; Tinnitus | 1971 |
Effects of salicylates on the gastric mucosa as revealed by roentgen examination and the gastrocamera.
Topics: Aspirin; Clinical Trials as Topic; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Heartburn; Humans; Photography; Placebos; Salicylates; Tinnitus | 1971 |
Effect of salicylates on gastrointestinal protein loss in normal subjects.
Topics: Adult; Aged; Aluminum; Aspirin; Caffeine; Carbonates; Chromium Isotopes; Citrates; Digestive System; Gastrointestinal Hemorrhage; Humans; Magnesium; Middle Aged; Phenacetin; Placebos; Potassium Chloride; Proteins; Salicylates; Serum Albumin | 1967 |
[Effect of salicylates on the gastric mucous membrane, as studied by gastrokamera and radiography].
Topics: Aspirin; Cerebral Ventriculography; Humans; Intestinal Mucosa; Photography; Placebos; Salicylates | 1970 |
Salicylates in the management of rheumatoid arthritis.
Topics: Aminobenzoates; Arthritis, Rheumatoid; Aspirin; Blood Coagulation; Buffers; Dyspepsia; Gastritis; Gastrointestinal Hemorrhage; Humans; Intestinal Absorption; Kidney Diseases; Placebos; Salicylates; Sodium Salicylate; Tablets, Enteric-Coated | 1971 |
A clinical trial of a sustained-release aspirin in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Male; Salicylates | 1967 |
Sustained-release aspirin in children.
Topics: Adolescent; Arthritis, Juvenile; Aspirin; Child; Delayed-Action Preparations; Humans; Rheumatic Fever; Salicylates; Time Factors | 1968 |
The effect of salicylates on the hemostatic properties of platelets in man.
Topics: Adenine Nucleotides; Aspirin; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Cell Membrane Permeability; Culture Techniques; Electrophoresis; Humans; Male; Placebos; Salicylates; Sodium | 1968 |
Effects of salicylate on human temperature regulation.
Topics: Adult; Aspirin; Body Temperature Regulation; Calorimetry; Fever; Humans; Infusions, Parenteral; Male; Salicylates; Sodium Salicylate; Time Factors | 1968 |
Conjoint clinic on pain and analgesia.
Topics: Analgesia; Analgesics; Aspirin; Cyclazocine; Humans; Morphine; Narcotic Antagonists; Pain; Phenacetin; Placebos; Salicylates | 1966 |
Comparison of the effects of regular and enteric-coated aspirin on gastroduodenal mucosa of man.
Topics: Adult; Aspirin; Duodenal Diseases; Duodenum; Erythema; Gastric Mucosa; Humans; Intestinal Mucosa; Pyloric Antrum; Salicylates; Stomach Diseases; Tablets, Enteric-Coated | 1980 |
Efficacy of ipecac and activated charcoal/cathartic. Prevention of salicylate absorption in a simulated overdose.
Topics: Adult; Aspirin; Cathartics; Charcoal; Drug Evaluation; Humans; Intestinal Absorption; Ipecac; Magnesium Sulfate; Random Allocation; Salicylates | 1984 |
Endoscopic evaluation of the comparative effects of acetylsalicylic acid and choline magnesium trisalicylate on human gastric and duodenal mucosa.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Choline; Clinical Trials as Topic; Double-Blind Method; Duodenum; Endoscopy; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Middle Aged; Random Allocation; Salicylates | 1983 |
Aspirin in the treatment of juvenile arthritis.
Topics: Arthritis, Juvenile; Aspirin; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Humans; Liver Diseases; Protein Binding; Salicylates; Serum Albumin | 1983 |
Efficacy and safety of a non-acetylated salicylate, choline magnesium trisalicylate, in the treatment of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Choline; Clinical Trials as Topic; Double-Blind Method; Humans; Random Allocation; Salicylates | 1983 |
Fibrinolytic activity after administration of diflunisal and aspirin. A double-blind, randomized, placebo-controlled clinical trial.
Topics: Adult; Aspirin; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Fibrinolysis; Fibrinolytic Agents; Humans; Kaolin; Male; Placebos; Random Allocation; Salicylates | 1983 |
The effect of antacid and aspirin on the bioavailability of isofezolac in man.
Topics: Adult; Aluminum Compounds; Antacids; Anti-Inflammatory Agents; Aspirin; Biological Availability; Blood Proteins; Drug Interactions; Female; Humans; Kinetics; Phosphates; Protein Binding; Pyrazoles; Salicylates; Salicylic Acid | 1984 |
Effect of gastric pH on antidotal efficacy of activated charcoal in man.
Topics: Absorption; Adult; Antidotes; Aspirin; Charcoal; Disopyramide; Female; Gastric Acid; Gastric Acidity Determination; Humans; Magnesium Hydroxide; Male; Middle Aged; ortho-Aminobenzoates; Salicylates; Salicylic Acid | 1984 |
Diflunisal protects human gastric mucosa against damage by indomethacin.
Topics: Adult; Aspirin; Diflunisal; Dinoprostone; Female; Gastric Mucosa; Humans; Indomethacin; Male; Membrane Potentials; Prostaglandins E; Salicylates | 1983 |
[Aspirin and gastroduodenal toxicity. A double-blind endoscopic study of the effects of placebo, aspirin and lysine acetylsalicylate in healthy subjects].
Topics: Adult; Aspirin; Double-Blind Method; Duodenal Diseases; Duodenum; Endoscopy; Female; Gastric Mucosa; Humans; Male; Salicylates; Stomach; Stomach Diseases; Time Factors | 1984 |
Double-blind study of the analgesic activity of fosfosal in patients with musculoskeletal and articular pain: comparison with lysine acetylsalicylate and placebo.
Topics: Aged; Analgesics; Aspirin; Bone Diseases; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Joint Diseases; Lysine; Middle Aged; Muscular Diseases; Organophosphates; Organophosphorus Compounds; Pain; Placebos; Salicylates; Stomach | 1981 |
Reduced faecal blood loss in patients receiving choline magnesium trisalicylate ('Trilisate') when compared with aspirin.
Topics: Adolescent; Adult; Aspirin; Choline; Humans; Male; Melena; Salicylates | 1983 |
[Short-term therapy of painful muscular disorders. Results of a multicenter double-blind test of 2 new suppository preparations with and without codeine].
Topics: Arthritis; Aspirin; Clinical Trials as Topic; Codeine; Diphenhydramine; Double-Blind Method; Drug Combinations; Humans; Meprobamate; Muscle Rigidity; Nerve Compression Syndromes; Nicotinic Acids; Osteoarthritis; Pain; Plant Extracts; Salicylamides; Salicylates; Spinal Nerve Roots; Suppositories | 1983 |
Effects of diflunisal on platelet function and fecal blood loss.
Topics: Adult; Aspirin; Blood Platelets; Diflunisal; Double-Blind Method; Feces; Female; Gastrointestinal Hemorrhage; Humans; Male; Malondialdehyde; Placebos; Platelet Aggregation; Platelet Function Tests; Random Allocation; Salicylates; Time Factors | 1981 |
Enteric-coated pelletized aspirin. Gastrointestinal blood loss and bioavailability.
Topics: Aspirin; Biological Availability; Gastrointestinal Hemorrhage; Humans; Salicylates; Tablets, Enteric-Coated | 1981 |
Diflunisal and aspirin: a comparative study in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Humans; Middle Aged; Salicylates | 1980 |
A controlled trial of magnesium dithiosalicylate compared with aspirin in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Salicylates | 1980 |
The efficacy and tolerability of diflunisal and ASA in the relief of postoperative pain in oral surgery.
Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Diflunisal; Female; Humans; Male; Middle Aged; Pain, Postoperative; Salicylates; Tooth Extraction; Tooth, Impacted | 1980 |
Comparison of serum salicylate levels and gastro-intestinal blood loss between salsalate (Disalcid)and other forms of salicylates.
Topics: Aspirin; Clinical Trials as Topic; Female; Gastrointestinal Hemorrhage; Humans; Male; Salicylates | 1981 |
Diflunisal in rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Humans; Male; Middle Aged; Salicylates; Time Factors | 1981 |
Comparison of diflunisal and acetylsalicylic acid in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diflunisal; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Salicylates | 1981 |
Saline catharsis: effect on aspirin bioavailability in combination with activated charcoal.
Topics: Adult; Aspirin; Biological Availability; Cathartics; Charcoal; Feces; Female; Humans; Intestinal Absorption; Kinetics; Male; Salicylates; Salicylic Acid; Sodium; Sulfates | 1982 |
Efficacy and pharmacokinetics of aspirin in post-operative dental pain.
Topics: Adult; Aspirin; Female; Half-Life; Humans; Kinetics; Male; Pain, Postoperative; Salicylates; Salicylic Acid; Tooth Extraction | 1982 |
[Comparison of the efficacy of diflunisal and acetylsalicylic acid in rheumatoid arthritis (author's transl)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Diflunisal; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Salicylates | 1981 |
Displacement of phenytoin from plasma binding sites by salicylate.
Topics: Adult; Aspirin; Binding Sites; Drug Interactions; Humans; Male; Phenytoin; Protein Binding; Salicylates; Time Factors | 1980 |
[Diflunisal in the treatment of coxarthrosis and gonarthrosis. A comparative double-blind study with acetylsalicylic acid].
Topics: Adult; Aged; Aspirin; Diflunisal; Double-Blind Method; Drug Evaluation; Female; Hip; Humans; Knee; Male; Middle Aged; Osteoarthritis; Salicylates | 1980 |
Comparative plasma salicylate and urine salicylurate levels following administration of aspirin, magnesium salicylate, and choline magnesium trisalicylate.
Topics: Adolescent; Adult; Aspirin; Choline; Glycine; Hippurates; Humans; Hydrolysis; Kinetics; Male; Salicylates | 1980 |
Platelet count, antiplatelet therapy and pulmonary embolism--a prospective study in patients with hip surgery.
Topics: Aged; Aged, 80 and over; Aspirin; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Heparin; Hip Fractures; Hip Prosthesis; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Count; Postoperative Complications; Prospective Studies; Pulmonary Embolism; Radionuclide Imaging; Salicylates; Thrombophlebitis; Treatment Outcome; Ultrasonography; Vomiting | 1995 |
Inter-individual variations of the effect of low dose aspirin regime on platelet cyclooxygenase activity.
Topics: Adult; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Humans; Male; Middle Aged; Prostaglandin-Endoperoxide Synthases; Reference Values; Salicylates; Salicylic Acid | 1994 |
Effects of nocloprost clathrate on absorption of acetylsalicylic acid.
Topics: Acetylation; Administration, Oral; Adult; Aspirin; beta-Cyclodextrins; Chromatography, High Pressure Liquid; Cyclodextrins; Drug Interactions; Hippurates; Humans; Intestinal Absorption; Male; Prostaglandins F, Synthetic; Salicylates; Salicylic Acid; Single-Blind Method; Vasodilator Agents | 1994 |
Single-dose effect of enteric-coated aspirin on platelet function and thromboxane generation in middle-aged men.
Topics: Aged; Aspirin; Blood Platelets; Humans; Male; Middle Aged; Salicylates; Tablets, Enteric-Coated; Thromboxane B2 | 1993 |
Topical acetylsalicylic, salicylic acid and indomethacin suppress pain from experimental tissue acidosis in human skin.
Topics: Acidosis; Administration, Topical; Adult; Aspirin; Cross-Over Studies; Double-Blind Method; Female; Humans; Indomethacin; Injections, Intradermal; Isotonic Solutions; Male; Middle Aged; Palliative Care; Pressure; Salicylates; Salicylic Acid; Skin Diseases | 1995 |
Variability in the pharmacokinetics and pharmacodynamics of low dose aspirin in healthy male volunteers.
Topics: Adult; Aspirin; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Salicylates; Salicylic Acid | 1995 |
Lack of influence of glycine on the single dose pharmacokinetics of acetylsalicylic acid in man.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aspirin; Cross-Over Studies; Double-Blind Method; Glycine; Half-Life; Humans; Male; Salicylates; Salicylic Acid; Therapeutic Equivalency | 1996 |
Dose-dependent competitive block by topical acetylsalicylic and salicylic acid of low pH-induced cutaneous pain.
Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Pain; Palliative Care; Salicylates; Salicylic Acid; Skin | 1996 |
Simultaneous determination of acetylsalicylic acid and salicylic acid in human plasma by high-performance liquid chromatography.
Topics: Analgesics, Non-Narcotic; Aspirin; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Quality Control; Reproducibility of Results; Salicylates; Salicylic Acid; Specimen Handling; Therapeutic Equivalency | 1996 |
Acetylsalicylate and salicylates in foods.
Topics: Aspirin; Chromatography, High Pressure Liquid; Cross-Over Studies; Food Analysis; Fruit; Humans; Magnoliopsida; Salicylates; Spices; Vegetables | 1997 |
Suppression of human colorectal mucosal prostaglandins: determining the lowest effective aspirin dose.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colon; Colorectal Neoplasms; Drug Administration Schedule; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Prostaglandins; Rectum; Salicylates; Salicylic Acid; Time Factors | 1997 |
[Comparison between effects of morning and evening administration of effervescent calcium carbasalate (equivalent of 160 mg aspirin) on the gastroduodenal mucosa in healthy volunteers].
Topics: Adult; Analgesics; Aspirin; Chronobiology Phenomena; Cross-Over Studies; Drug Tolerance; Duodenum; Female; Gastric Mucosa; Healthy Worker Effect; Humans; Intestinal Mucosa; Male; Platelet Aggregation; Salicylates; Thromboxane B2; Urea; Volunteers | 1997 |
[Comparative study of the effect of low-dosage acetylsalicylic acid and triflusal in the prevention of cardiovascular events among young adults with ischemic cerebrovascular disease].
Topics: Adult; Aspirin; Brain Ischemia; Cardiovascular Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Salicylates; Survival Rate | 1997 |
Skin and plasma levels of acetylsalicylic acid: a comparison between topical aspirin/diethyl ether mixture and oral aspirin in acute herpes zoster and postherpetic neuralgia.
Topics: Acute Disease; Administration, Oral; Administration, Topical; Aged; Analgesics; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Double-Blind Method; Ether; Female; Herpes Zoster; Herpesviridae Infections; Humans; Male; Middle Aged; Neuralgia; Pain; Pain Measurement; Salicylates; Salicylic Acid; Skin; Solvents; Treatment Outcome | 1998 |
Interaction of omeprazole with enteric-coated salicylate tablets.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Area Under Curve; Aspirin; Biological Availability; Cross-Over Studies; Double-Blind Method; Female; Half-Life; Humans; Male; Omeprazole; Salicylates; Tablets, Enteric-Coated | 1998 |
Effects of triflusal on arteriosclerosis progression assessed with high-resolution arterial ultrasound.
Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Arteriosclerosis; Aspirin; Carotid Artery Diseases; Chi-Square Distribution; Disease Progression; Double-Blind Method; Female; Femoral Artery; Humans; Male; Middle Aged; Pilot Projects; Placebos; Platelet Aggregation Inhibitors; Salicylates; Stomach; Tunica Intima; Tunica Media; Ultrasonography | 1999 |
Randomized comparative trial of triflusal and aspirin following acute myocardial infarction.
Topics: Aged; Aspirin; Cerebrovascular Disorders; Double-Blind Method; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Salicylates; Spain; Treatment Outcome | 2000 |
Evaluation of the Clot Signature Analyzer as a hemostasis test in healthy volunteers exposed to low doses of aspirin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Bleeding Time; Blood Coagulation Tests; Collagen; Evaluation Studies as Topic; Female; Hematologic Tests; Hemostasis; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Reproducibility of Results; Salicylates; Thrombosis | 1999 |
Economic evaluation of triflusal and aspirin in the treatment of acute myocardial infarction.
Topics: Acute Disease; Aspirin; Double-Blind Method; Drug Costs; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Salicylates; Spain | 2002 |
Comparison of triflusal and aspirin for prevention of vascular events in patients after cerebral infarction: the TACIP Study: a randomized, double-blind, multicenter trial.
Topics: Aspirin; Cardiovascular Diseases; Cerebral Infarction; Double-Blind Method; Female; Hemorrhage; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Salicylates; Secondary Prevention; Stroke; Survival Analysis | 2003 |
Pharmacokinetic and pharmacodynamic differences between two low dosages of aspirin may affect therapeutic outcomes.
Topics: Adult; Area Under Curve; Aspirin; Blood Platelets; Chromatography, High Pressure Liquid; Cross-Over Studies; Dose-Response Relationship, Drug; Epoprostenol; Female; Fibrinolytic Agents; Humans; Male; Platelet Aggregation Inhibitors; Salicylates; Tablets, Enteric-Coated; Thromboxane B2; Treatment Outcome | 2003 |
Triflusal vs aspirin for prevention of cerebral infarction: a randomized stroke study.
Topics: Aged; Aspirin; Cerebral Infarction; Double-Blind Method; Female; Follow-Up Studies; Humans; Ischemic Attack, Transient; Male; Middle Aged; Odds Ratio; Pilot Projects; Platelet Aggregation Inhibitors; Salicylates; Secondary Prevention; Stroke; Survival Analysis; Treatment Outcome | 2004 |
Significance of salicylate intolerance in diseases of the lower gastrointestinal tract.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colitis, Ulcerative; Crohn Disease; Diet; Drug Hypersensitivity; Food Hypersensitivity; Gastrointestinal Diseases; Humans; Irritable Bowel Syndrome; Lower Gastrointestinal Tract; Malabsorption Syndromes; Mesalamine; Salicylates | 2005 |
Inhibition of thromboxane biosynthesis by triflusal in type 2 diabetes mellitus.
Topics: Adult; Aged; Aspirin; Biomarkers; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Radioimmunoassay; Retrospective Studies; Salicylates; Thromboxane B2; von Willebrand Factor | 2005 |
Safety of triflusal (antiplatelet drug) in patients with aspirin-exacerbated respiratory diseases.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multivariate Analysis; Probability; Reference Values; Respiratory Function Tests; Risk Assessment; Salicylates; Severity of Illness Index; Single-Blind Method; Treatment Outcome | 2008 |
Pharmacokinetic study of copper (II) acetylsalicylate.
Topics: Administration, Oral; Adolescent; Adult; Aspirin; Chromatography, High Pressure Liquid; Female; Humans; Male; Organometallic Compounds; Salicylates; Young Adult | 2008 |
Comparison of oral aspirin versus topical applied methyl salicylate for platelet inhibition.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Area Under Curve; Aspirin; Cross-Over Studies; Double-Blind Method; Epinephrine; Humans; Immunoenzyme Techniques; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Salicylates; Statistics, Nonparametric; Thromboxane B2; Time Factors | 2008 |
Triflusal and aspirin have different effects on inflammatory biomarkers measured in patients with acute ischemic stroke.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Aspirin; Biomarkers; Brain Ischemia; Female; Humans; Inflammation Mediators; Logistic Models; Male; Middle Aged; Neuroprotective Agents; Pilot Projects; Platelet Aggregation Inhibitors; Prospective Studies; Salicylates; Stroke; Time Factors; Treatment Outcome | 2009 |
Predictors of adherence to secondary preventive medication in stroke patients.
Topics: Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Attitude to Health; Brain Ischemia; Cognition; Female; Humans; Longitudinal Studies; Male; Medication Adherence; Psychiatric Status Rating Scales; Salicylates; Secondary Prevention; Severity of Illness Index; Stroke | 2011 |
Triflusal and aspirin in the secondary prevention of atherothrombotic ischemic stroke: a very long-term follow-up.
Topics: Aged; Aspirin; Brain Ischemia; Dyspepsia; Female; Follow-Up Studies; Hemorrhage; Humans; Incidence; Intracranial Arteriosclerosis; Ischemic Attack, Transient; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Recurrence; Salicylates; Secondary Prevention; Vascular Diseases | 2014 |
Treatment of aspirin exacerbated respiratory disease with a low salicylate diet: a pilot crossover study.
Topics: Adult; Aged; Aspirin; Asthma; Cross-Over Studies; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Nasal Polyps; Pilot Projects; Prospective Studies; Respiratory Tract Diseases; Rhinitis; Salicylates; Single-Blind Method; Sinusitis | 2015 |
Effect of Triflusal on Primary Vascular Dysregulation Compared with Aspirin: A Double-Blind, Randomized, Crossover Trial.
Topics: Adult; Aspirin; Cardiovascular Diseases; Cross-Over Studies; Double-Blind Method; Female; Humans; Indocyanine Green; Male; Middle Aged; Perfusion Imaging; Platelet Aggregation Inhibitors; Recurrence; Salicylates; Treatment Outcome | 2015 |
Comparison of Triflusal with Aspirin in the Secondary Prevention of Atherothrombotic Events; Α Randomised Clinical Trial.
Topics: Aged; Aspirin; Brain Ischemia; Coronary Artery Disease; Cyclooxygenase Inhibitors; Female; Greece; Hemorrhage; Humans; Intracranial Embolism; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Recurrence; Risk Factors; Salicylates; Secondary Prevention; Stroke; Time Factors; Treatment Outcome | 2019 |
Effect of low salicylate diet on clinical and inflammatory markers in patients with aspirin exacerbated respiratory disease - a randomized crossover trial.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; Biomarkers; Cross-Over Studies; Female; Humans; Male; Middle Aged; Nasal Polyps; Salicylates; Sino-Nasal Outcome Test; Sinusitis | 2021 |
1278 other study(ies) available for aspirin and salicylates
| Article | Year |
|---|---|
Oral antipyretic therapy: evaluation of benorylate, an ester of acetylsalicylic acid and paracetamol.
Topics: Acetaminophen; Aspirin; Body Temperature; Child; Child, Preschool; Fever; Humans; Infant; Salicylates; Time Factors | 1975 |
The absorption of benorylate from everted sacs of rat intestinal.
Topics: Animals; Aspirin; Biological Transport; Female; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Male; Pylorus; Rats; Salicylates | 1975 |
Benorylate interaction with indomethacin and phenylbutazone.
Topics: Animals; Arthritis; Aspirin; Drug Interactions; Drug Synergism; Fever; Indomethacin; Male; Phenylbutazone; Rats; Salicylates; Time Factors | 1976 |
Gastric mucosal lesions produced by intravenous infusion of aspirin in cats.
Topics: Animals; Aspirin; Body Weight; Cats; Dose-Response Relationship, Drug; Female; Gastric Mucosa; Hydrogen-Ion Concentration; Infusions, Parenteral; Ions; Male; Membrane Potentials; Salicylates; Stomach Ulcer | 1976 |
Immunological mechanisms in aspirin hypersensitivity. Studies on the immunogenicity of free aspirin.
Topics: Anhydrides; Animals; Antibodies; Antibody Formation; Antibody Specificity; Aspirin; Cell Membrane; Drug Hypersensitivity; Erythrocytes; Female; Guinea Pigs; Hydrogen-Ion Concentration; Male; Rabbits; Salicylates; Temperature; Time Factors | 1976 |
Interaction of salicylic acid with adenosine and adenosine triphosphate. Potential mechanism of intensifying acetylsalicylic acid-induced GI blood loss.
Topics: Adenosine; Adenosine Triphosphate; Aspirin; Chemical Phenomena; Chemistry; Gastrointestinal Hemorrhage; Hydrogen-Ion Concentration; Salicylates; Surface Tension | 1976 |
Acute hypotension due to carrageenan, arachidonic acid and slow reacting substance C in the rabbit: role of platelets and nature of pharmacological antagonism.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Aspirin; Autacoids; Blood Cell Count; Blood Platelets; Blood Pressure; Carrageenan; Drug Antagonism; Female; Glycogen; Immune Sera; In Vitro Techniques; Male; Platelet Aggregation; Prostaglandins; Rabbits; Respiration; Salicylates; Time Factors | 1977 |
Evaluation of copper complexes as potential anti-arthritic drugs.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Aspirin; Copper; Gastric Mucosa; Injections, Subcutaneous; Irritants; Rats; Salicylates | 1977 |
Effects of aspirin-like drugs on canine gastric mucosal blood flow and acid secretion.
Topics: Acetaminophen; Animals; Aspirin; Dogs; Female; Gastric Mucosa; Indomethacin; Muscle Contraction; Muscle, Smooth; Pentagastrin; Prostaglandins E; Prostaglandins F; Regional Blood Flow; Salicylates | 1977 |
The effect of anti-inflammatory drugs on retinal dystrophy in the rat.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cortisone; Light; Rats; Retina; Retinal Degeneration; Salicylates | 1977 |
Renal handling, turnover, and metabolism of salicylates in a desert rodent.
Topics: Animals; Aspirin; Desert Climate; Kidney; Kidney Cortex; Kidney Medulla; Male; Mice; Rodentia; Salicylates | 1977 |
Improved colorimetric determination of aspirin and salicylic acid concentrations in human plasma.
Topics: Aspirin; Humans; Hydrogen-Ion Concentration; Light; Methods; Salicylates; Spectrophotometry | 1978 |
Comparative metabolism of benorylate and an equivalent mixture of aspirin and paracetamol in neonate and adult rabbits.
Topics: Acetaminophen; Animals; Animals, Newborn; Aspirin; Female; Glucuronates; Male; Rabbits; Salicylates | 1977 |
Salicylic acid fails to inhibit generation of thromboxane A2 activity in platelets after in vivo administration to the rat.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Depression, Chemical; Male; Platelet Aggregation; Rats; Salicylates; Thromboxane A2; Thromboxanes; Time Factors | 1978 |
Inhibitors of gastric lesions in the rat.
Topics: Animals; Aspirin; Disease Models, Animal; Female; Glutamine; Histamine Antagonists; Indomethacin; Ligation; Pylorus; Rats; Salicylates; Stomach Ulcer; Stress, Physiological | 1978 |
[Comparative experimental studies in animals and humans on gastrointestinal blood loss following antirheumatic pharmacotherapy (author's transl)].
Topics: Animals; Aspirin; Gastrointestinal Hemorrhage; Humans; Iron; Iron Radioisotopes; Male; Rats; Salicylates; Time Factors | 1978 |
The wetting of powders of acetylsalicylic acid, salicylic acid, phenacetin and paracetamol.
Topics: Acetaminophen; Aspirin; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Phenacetin; Powders; Salicylates; Surface Tension | 1978 |
[Preliminary studies on the absorption of etherylate, benorylate and acetylsalicylic acid].
Topics: Animals; Aspirin; Intestinal Absorption; Male; Rabbits; Rats; Salicylates | 1978 |
[Platelet aggregation inhibition provoked by eterilate, benorylate and their molecular components, in comparison with acetylsalicylic acid].
Topics: Acetanilides; Animals; Aspirin; Depression, Chemical; Platelet Aggregation; Rats; Salicylates | 1978 |
[Comparative study of acute and chronic toxicity of etherilate, benorylate and acetylsalicylic acid].
Topics: Acetanilides; Animals; Aspirin; Blood Coagulation; Body Weight; Liver; Male; Mice; Rats; Salicylates; Stomach | 1978 |
[Anti-inflammatory and analgesic effects of eterilate, benorylate and acetylsalicylic acid].
Topics: Acetanilides; Animals; Anti-Inflammatory Agents; Aspirin; Female; Inflammation; Male; Mice; Pain; Rats; Salicylates | 1978 |
Gastric ulceration and the concentration of salicylate in plasma in rats after administration of 14C-labelled aspirin and its synthetic triglyceride, 1,3-dipalmitoyl-2(2'-acetoxy-[14C]carboxylbenzoyl) glycerol.
Topics: Animals; Aspirin; Chyle; Male; Rats; Salicylates; Stomach Ulcer; Time Factors; Triglycerides | 1978 |
Inhibition of leucocyte migration by salicylates and indomethacin.
Topics: Animals; Aspirin; Cell Movement; In Vitro Techniques; Indomethacin; Leukocytes; Male; Pleura; Rats; Salicylates; Time Factors | 1978 |
[Experimental comparative study of acute toxicity and gastric tolerance of eterylate, benorylate and acetylsalicylic acid (author's transl)].
Topics: Acetanilides; Acute Disease; Animals; Anti-Inflammatory Agents; Aspirin; Drug Evaluation, Preclinical; Gastric Mucosa; Lethal Dose 50; Mice; Salicylates; Stomach Ulcer; Time Factors | 1978 |
Synthesis and pharmacological properties of eterylate, a new derivative of acetylsalicylic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Digestive System; Female; Male; Mice; Rats; Salicylates | 1978 |
Aspirin-caffeine interaction in the rat.
Topics: Animals; Aspirin; Brain Chemistry; Caffeine; Drug Interactions; Female; Motor Activity; Rats; Salicylates | 1979 |
Aspirin-phenacetin interaction in the rat.
Topics: Animals; Aspirin; Drug Interactions; Female; Motor Activity; Phenacetin; Rats; Salicylates; Time Factors | 1979 |
Adrenocortical stimulation and the anti-inflammatory actions of salicylates.
Topics: Adrenal Cortex; Adrenalectomy; Animals; Anti-Inflammatory Agents; Aspirin; Electric Stimulation; Leukocyte Count; Rats; Salicylates | 1979 |
The inhibition of cyclo-oxygenase of rabbit platelets by aspirin is prevented by salicylic acid and by phenanthrolines.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dithiothreitol; In Vitro Techniques; Indomethacin; Phenanthrolines; Platelet Aggregation; Rabbits; Salicylates; Thromboxane A2; Time Factors | 1978 |
Meseclazone, 5-chlorosalicylic acid and acetylsalicylic acid. Comparison of their effects on in vitro and ex vivo platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Aspirin; Blood Coagulation Tests; Collagen; Guinea Pigs; Male; Oxazines; Platelet Aggregation; Rats; Salicylates; Thrombin | 1978 |
Aspirin-like drugs interfere with arachidonate metabolism by inhibition of the 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid peroxidase activity of the lipoxygenase pathway.
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Humans; Hydroxy Acids; Indomethacin; Lipoxygenase Inhibitors; Peroxidases; Salicylates; Thrombin | 1979 |
Prostaglandins and gastro-intestinal damage - a comment.
Topics: Aspirin; Cyclooxygenase Inhibitors; Gastric Juice; Gastric Mucosa; Humans; Prostaglandins; Salicylates | 1979 |
The pharmacokinetics and metabolism of diclofenac sodium (Voltarol) in animals and man.
Topics: Absorption; Animals; Aspirin; Bile; Diclofenac; Dogs; Drug Interactions; Enterohepatic Circulation; Feces; Haplorhini; Humans; Kinetics; Macaca mulatta; Mice; Papio; Phenylacetates; Protein Binding; Rats; Salicylates; Tissue Distribution | 1979 |
Interference by sulfinpyrazone and salicylate of aspirin inhibition of platelet cyclooxygenase activity.
Topics: Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Prostaglandin-Endoperoxide Synthases; Salicylates; Sulfinpyrazone | 1979 |
Percutaneous absorption on the relevance of in vitro data.
Topics: Aspirin; Caffeine; Carbon Radioisotopes; Chloramphenicol; Chlorobenzenes; Hippurates; Humans; In Vitro Techniques; Kinetics; Models, Biological; Niacinamide; Nicotinic Acids; Phenols; Salicylates; Skin Absorption; Thiourea; Urea | 1975 |
Kinetics of salicylate metabolism.
Topics: Arthritis, Rheumatoid; Aspirin; Back Pain; Female; Humans; Male; Middle Aged; Salicylates | 1975 |
[The effect of locally applied Grisaldone or choline salicylate gel on bone healing after tooth extraction in animal experiments].
Topics: Administration, Topical; Animals; Aspirin; Choline; Rabbits; Salicylates; Solubility; Tooth Extraction; Wound Healing | 1977 |
Effect of salicylates on histamine and L-histidine metabolism. Inhibition of imidazoleacetate phosphoribosyl transferase.
Topics: Anti-Inflammatory Agents; Aspirin; Carbon-Nitrogen Ligases; Depression, Chemical; Histamine; Histidine; Imidazoles; Pentosephosphates; Phosphotransferases; Salicylates | 1976 |
Comparison of the inhibitory effects of acetylsalicylic acid and trifusal on enzymes related to thrombosis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aspirin; Cattle; Cyclooxygenase Inhibitors; Fibrinolytic Agents; Horses; In Vitro Techniques; Microsomes; Myocardial Contraction; Oxidoreductases; Salicylates; Sheep; Thrombosis; Thromboxane-A Synthase | 1979 |
Experimental salicylate intoxication in young baboons. A preliminary report.
Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Alkalosis, Respiratory; Ammonium Chloride; Animals; Aspirin; Bicarbonates; Blood; Carbon Dioxide; Haplorhini; Hydrogen-Ion Concentration; Medulla Oblongata; Papio; Permeability; Protein Binding; Salicylates; Serum Albumin | 1975 |
Fetal acquisition and neonatal elimination of a large amount of salicylate. Study of a neonate whose mother regularly took therapeutic doses of aspirin during pregnancy.
Topics: Arthritis; Aspirin; Female; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Kinetics; Maternal-Fetal Exchange; Pregnancy; Salicylates | 1975 |
A simultaneous determination of acetylsalicylic acid, salicylic acid and salicylamide in plasma by gas liquid chromatography.
Topics: Administration, Oral; Adult; Aspirin; Chromatography, Gas; Half-Life; Humans; Male; Salicylamides; Salicylates; Time Factors | 1975 |
Some characteristics of the prostaglandin synthesizing system in rabbit kidney microsomes.
Topics: Aldosterone; Animals; Arachidonic Acids; Aspirin; Dexamethasone; Enzyme Activation; Epinephrine; Fludrocortisone; Glutathione; Hydrogen-Ion Concentration; Kidney; Kinetics; Male; Microsomes; Mixed Function Oxygenases; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F; Rabbits; Salicylates | 1975 |
Prostaglandins and the anti-inflammatory activities of aspirin and sodium salicylate.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Carrageenan; Cell Migration Inhibition; Female; In Vitro Techniques; Inflammation; Leukocytes; Prostaglandins; Rats; Salicylates; Time Factors | 1975 |
Decreased serum salicylate concentrations in children with rheumatic fever treated with antacid.
Topics: Adult; Age Factors; Aluminum Hydroxide; Antacids; Aspirin; Biological Availability; Child; Humans; Hydrogen-Ion Concentration; Hydroxides; Kidney; Magnesium; Male; Rheumatic Fever; Salicylates | 1975 |
Update on the treatment of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin; Drug Therapy, Combination; Glucocorticoids; Gold; Humans; Patient Education as Topic; Physical Therapy Modalities; Rest; Salicylates | 1979 |
A pharmacokinetic approach to the understanding of therapeutic effects and side effects of salicylates.
Topics: Animals; Anti-Inflammatory Agents; Antipyrine; Aspirin; Gastric Mucosa; Humans; Indomethacin; Kidney; Phenylbutazone; Salicylates; Stomach; Tissue Distribution | 1977 |
Salicylate toxicology.
Topics: Adolescent; Adult; Animals; Aspirin; Child; Child, Preschool; Drug Hypersensitivity; Female; Fetus; Humans; Kidney; Liver; Pregnancy; Salicylates | 1977 |
Non-accidental poisoning with salicylate.
Topics: Administration, Oral; Aspirin; Humans; Infant; Male; New Jersey; Poisoning; Salicylates | 1979 |
[Mechanism of the antipyretic effect of acetylsalicylic acid and salicylic acid in rabbits (author's transl)].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Temperature; Dose-Response Relationship, Drug; Half-Life; Injections, Intravenous; Injections, Intraventricular; Rabbits; Salicylates; Time Factors | 1977 |
Gastrointestinal and other side-effects from the use of aspirin and related drugs; biochemical studies on the mechanisms of gastrotoxicity.
Topics: Animals; Aspirin; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Guinea Pigs; Humans; Pregnancy; Prostaglandins E; Rats; Salicylates; Stomach; Stomach Ulcer; Stress, Psychological; Structure-Activity Relationship; Swine | 1977 |
Prevention by bismuth subsalicylate of gastric mucosal lesions in response to noxious stimuli in rats.
Topics: Animals; Aspirin; Bismuth; Cold Temperature; Condiments; Ethanol; Female; Gastrointestinal Hemorrhage; Male; Rats; Restraint, Physical; Salicylates; Time Factors | 1978 |
The effects of aspirin and other non-steroid anti-inflammatory/analgesic drugs on gastro-intestinal mucus glycoprotein biosynthesis in vivo: relationship to ulcerogenic actions.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Glycoproteins; Intestinal Mucosa; Male; Rats; Salicylates; Stomach Ulcer; Threonine; Time Factors | 1978 |
Salicylate-induced enzymuria: comparison with other anti-inflammatory agents.
Topics: Acetaminophen; Acetylglucosaminidase; Adult; Anti-Inflammatory Agents; Aspirin; Gold; Hexosaminidases; Humans; Ibuprofen; Indomethacin; Kidney; Kidney Diseases; Lysosomes; Rheumatic Diseases; Salicylates | 1978 |
Diflunisal, a new-acting analgesic and prostaglandin inhibitor: effect of concomitant acetylsalicylic acid therapy on ototoxicity and on disposition of both drugs.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Interactions; Hemostasis; Humans; Male; Prostaglandins E; Salicylates; Tinnitus | 1979 |
Antirheumatic agents.
Topics: Adrenal Cortex Hormones; Antimalarials; Aspirin; Azathioprine; Chloroquine; Cyclophosphamide; Gold; Humans; Hydroxychloroquine; Immunosuppressive Agents; Indomethacin; Penicillamine; Phenylbutazone; Phenylpropionates; Rheumatic Diseases; Salicylates; Sulindac; Tolmetin | 1979 |
Glycerides as prodrugs. 1. Synthesis and antiinflammatory activity of 1,3-bis(alkanoyl)-2-(O-acetylsalicyloyl)glycerides (aspirin triglycerides).
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Dose-Response Relationship, Drug; Edema; Male; Rats; Salicylates; Stomach Ulcer; Structure-Activity Relationship; Time Factors; Triglycerides | 1979 |
Aspirin and gastrointestional bleeding. Interest of plasma salicylate determination.
Topics: Aspirin; Duodenal Diseases; Enteritis; Gastritis; Gastrointestinal Hemorrhage; Humans; Peptic Ulcer Hemorrhage; Salicylates | 1979 |
Drug treatment of arthritis in the elderly.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Gold; Humans; Immunosuppressive Agents; Indomethacin; Levamisole; Penicillamine; Phenylbutazone; Propionates; Salicylates | 1979 |
Discovery of diflunisal.
Topics: Acetylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemistry, Pharmaceutical; Fluorobenzenes; History, 20th Century; Salicylates; Structure-Activity Relationship; United States | 1977 |
[Comparative studies on the bacteriostatic effect of "Grisaldon" and "Cholinesalicylate gel"].
Topics: Anti-Infective Agents, Local; Aspirin; Bacteria; Candida albicans; Choline; Drug Combinations; Dry Socket; Humans; Salicylates; Surgical Wound Infection; Tooth Extraction | 1977 |
A clergyman makes a stellar contribution to medicine.
Topics: Aspirin; Clergy; England; History, 18th Century; Plants, Medicinal; Salicylates | 1978 |
Alternatives to aspirin, derived from biological sources.
Topics: Animals; Aspirin; Enterobacter; Escherichia coli; Female; Inflammation; Male; Mice; Platelet Aggregation; Rats; Salicylates; Stomach Ulcer; Swine | 1977 |
The effect of adsorbant and anti-inflammatory drugs on secretion in ligated segments of pig intestine infected with Escherichia coli.
Topics: Animals; Anti-Inflammatory Agents; Antidiarrheals; Aspirin; Bismuth; Enterotoxins; Escherichia coli; Escherichia coli Infections; Intestinal Secretions; Jejunum; Kaolin; Ligation; Lincomycin; Methylprednisolone; Organometallic Compounds; Pectins; Polymyxin B; Salicylates; Swine; Swine Diseases | 1978 |
Thrombogenic effect of high-dose aspirin in rabbits. Relationship to inhibition of vessel wall synthesis of prostaglandin I2-like activity.
Topics: Animals; Aspirin; Blood Coagulation; Blood Vessels; Dose-Response Relationship, Drug; Epoprostenol; Fibrin; Prostaglandins; Rabbits; Salicylates; Serotonin; Veins | 1978 |
Ontogenic drug studies in calves. II. Changes in salicylate levels and metabolism in calves with diarrhoea.
Topics: Animals; Animals, Newborn; Aspirin; Cattle; Cattle Diseases; Cholera Toxin; Diarrhea; Escherichia coli Infections; Mice; Salicylates; Time Factors | 1979 |
Comparative effects of aspirin and diflunisal on prostaglandin synthetase from human platelets and sheep seminal vesicles.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Fluorobenzenes; Humans; In Vitro Techniques; Male; Mixed Function Oxygenases; Salicylates; Seminal Vesicles; Sheep | 1977 |
Comparative distribution and embryotoxicity of acetylsalicylic acid in pregnant rats and rhesus monkeys.
Topics: Animals; Aspirin; Embryo, Mammalian; Female; Fetal Death; Fetal Resorption; Haplorhini; Macaca mulatta; Maternal-Fetal Exchange; Models, Biological; Pregnancy; Rats; Salicylates; Species Specificity; Teratogens; Time Factors | 1977 |
Pharmacokinetics of salicylates in elderly.
Topics: Adult; Aged; Aspirin; Half-Life; Humans; Kinetics; Salicylates; Spectrometry, Fluorescence | 1979 |
Rational use of aspirin and nonsteroidal anti-inflammatory drugs in inflammatory arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Female; Humans; Male; Salicylates | 1979 |
[Interactions and side-effects of non-steroid anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents; Aspirin; Drug Antagonism; Drug Interactions; Drug Synergism; Humans; Indomethacin; Phenylbutazone; Salicylates | 1979 |
Plasma salicylate levels in rheumatoid arthritis: a comparison between micro-encapsulated and conventional aspirin.
Topics: Arthritis, Rheumatoid; Aspirin; Capsules; Humans; Salicylates; Tablets | 1979 |
Simultaneous liquid-chromatographic quantitation of salicylic acid, salicyluric acid, and gentisic acid in plasma.
Topics: Aspirin; Chromatography, High Pressure Liquid; Drug Stability; Gentisates; Glycine; Hippurates; Humans; Kinetics; Salicylates; Spectrophotometry, Ultraviolet | 1979 |
Modified USP assay for simultaneous determination of aspirin and nonaspirin salicylates in aspirin and buffered aspirin tablets.
Topics: Aspirin; Buffers; Drug Stability; Indicators and Reagents; Methanol; Methods; Pharmacopoeias as Topic; Salicylates; Tablets; United States | 1979 |
Interaction between levamisole and aspirin in man.
Topics: Adult; Aspirin; Drug Interactions; Female; Humans; Levamisole; Male; Salicylates; Saliva; Time Factors | 1979 |
Inhibition of human leucocytes locomotion by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Cell Movement; Chemotaxis, Leukocyte; Depression, Chemical; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Neutrophils; Salicylates | 1979 |
Regular and enteric coated aspirin: a reevaluation.
Topics: Aged; Aspirin; Drug Evaluation; Female; Humans; Male; Middle Aged; Salicylates; Tablets; Tablets, Enteric-Coated | 1979 |
Comparison of kaolin-pectin and activated charcoal for inhibition of aspirin absorption.
Topics: Adult; Aspirin; Biological Availability; Charcoal; Drug Combinations; Female; Humans; Intestinal Absorption; Kaolin; Kinetics; Male; Pectins; Salicylates; Suspensions | 1979 |
Increased dipyridamole plasma concentrations associated with salicylate administration. Relationship to effects on platelet aggregation in vivo.
Topics: Animals; Aspirin; Collagen; Dipyridamole; Drug Synergism; Drug Therapy, Combination; Glucuronates; Humans; Platelet Aggregation; Rabbits; Salicylates | 1979 |
Isolation of salicylsalicylic acid, acetylsalicylsalicylic acid, and acetylsalicylic anhydride from aspirin tablets by extraction and high-pressure liquid chromatography.
Topics: Anhydrides; Aspirin; Chromatography, High Pressure Liquid; Methods; Salicylates; Tablets | 1979 |
Prolonged paradoxical effect of aspirin on platelet behaviour and bleeding time in man.
Topics: Adult; Aspirin; Bleeding Time; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Female; Humans; Male; Partial Thromboplastin Time; Platelet Aggregation; Salicylates; Thromboxane A2; Time Factors | 1979 |
Effects of buffered aspirin and salicylate on the bio-electric potential difference across the human buccal mucosa [proceedings].
Topics: Adolescent; Adult; Aspirin; Buffers; Cheek; Female; Humans; Male; Membrane Potentials; Middle Aged; Mouth Mucosa; Salicylates | 1979 |
Aspirin and acetaminophen.
Topics: Acetaminophen; Antidotes; Arthritis, Juvenile; Aspirin; Child, Preschool; Female; Hemostasis; Humans; Hypersensitivity; Infant; Kinetics; Pregnancy; Salicylates; Stomach | 1979 |
Aspirin, salicylate and prostaglandins.
Topics: Animals; Arachidonic Acids; Aspirin; Carrageenan; Edema; Exudates and Transudates; Female; Gentisates; Leukocytes; Prostaglandins; Rats; Salicylates | 1979 |
Improved gas-liquid chromatographic-flame ionization detection assay of acetylsalicylic and salicylic acids.
Topics: Aspirin; Drug Contamination; Drug Stability; Flame Ionization; Humans; Methods; Salicylates; Tablets | 1979 |
Salicylate treatment of epidemic Kawasaki disease in New York City.
Topics: Aging; Aspirin; Child; Child, Preschool; Disease Outbreaks; Feces; Humans; Infant; Lymphatic Diseases; Mucocutaneous Lymph Node Syndrome; New York City; Salicylates | 1979 |
Time dependent changes in the pharmacokinetics of aspirin.
Topics: Adult; Aspirin; Circadian Rhythm; Half-Life; Humans; Kinetics; Male; Salicylates; Time Factors | 1979 |
[The influence of treatments with a quinine-lithium-salicylate combination or acetylsalicylic acid on hematopoiesis in mice (author's transl)].
Topics: Animals; Aspirin; Drug Combinations; Erythrocyte Count; Guinea Pigs; Hematocrit; Hematopoiesis; Leukocyte Count; Lithium; Male; Mice; Mice, Inbred CBA; Quinine; Salicylates; Time Factors | 1979 |
The effect of acetylsalicylic acid/salicylic acid mixtures on acetylcholinesterase activity in vitro.
Topics: Acetylcholinesterase; Animals; Aspirin; Brain; Cholinesterase Inhibitors; Drug Combinations; Erythrocytes; Humans; In Vitro Techniques; Male; Physostigmine; Rats; Salicylates | 1978 |
Ontogenic drug studies in calves. I. Age dependent salicylate levels and metabolism.
Topics: Aging; Animals; Animals, Newborn; Aspirin; Cattle; Salicylates | 1979 |
Pulmonary vascular effects of acetylsalicylic acid, chloroquine, dextran and methylprednisolone given after haemorrhagic shock in dogs.
Topics: Animals; Aspirin; Blood Coagulation; Chloroquine; Dextrans; Dogs; Hemodynamics; Lung; Methylprednisolone; Salicylates; Shock, Hemorrhagic; Vascular Resistance | 1977 |
Clinical importance of side-effects of drugs inhibiting platelet function.
Topics: Aspirin; Carbenicillin; Female; Hemorrhage; Humans; Nitrofurantoin; Penicillin G; Platelet Aggregation; Pregnancy; Salicylates | 1977 |
Contact eczema from methyl salicylate reproduced by oral aspirin (acetyl salicylic acid).
Topics: Aspirin; Chemical Phenomena; Chemistry; Dermatitis, Contact; Eczema; Humans; Male; Middle Aged; Ointments; Salicylates; Tablets | 1977 |
Effect of topical salicylic acid on animal epidermopoiesis.
Topics: Administration, Topical; Animals; Aspirin; Epidermis; Epithelium; Guinea Pigs; Hydrocortisone; Mitosis; Mitotic Index; Salicylates | 1978 |
Liquid chromatographic analysis of analgesics on amberlite XAD-7.
Topics: Acetaminophen; Acrylic Resins; Analgesics; Aspirin; Caffeine; Chromatography, Liquid; Drug Combinations; Phenacetin; Polystyrenes; Salicylamides; Salicylates; Tablets | 1978 |
Rational aspirin dosage regimens.
Topics: Adult; Aspirin; Body Weight; Drug Administration Schedule; Female; Humans; Kinetics; Male; Models, Biological; Salicylates | 1978 |
Salicylates in spinal fluid.
Topics: Aspirin; Child, Preschool; Humans; Male; Salicylates | 1978 |
Comparative antiphlogistic activity of meseclazone, 5-chlorosalicylic acid, acetylsalicylic acid, phenylbutazone, indomethacin and hydrocortisone in various rat paw edema models.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Benzoxazines; Drug Evaluation, Preclinical; Edema; Hydrocortisone; Indomethacin; Isoxazoles; Male; Oxazines; Phenylbutazone; Rats; Salicylates | 1978 |
Histamine augments gastric ulceration produced by intravenous aspirin in cats.
Topics: Animals; Aspirin; Cats; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Female; Gastric Mucosa; Histamine; Hydrochloric Acid; Male; Salicylates; Stomach Ulcer | 1978 |
Effect of phenolic acids and related compounds on gastric acid secretion in the rat.
Topics: Animals; Aspirin; Gallic Acid; Gastric Juice; Gastrins; Hydrolyzable Tannins; Hydroxybenzoates; Rats; Salicylates | 1978 |
Effects of compression force, particle size, and lubricants on dissolution rate.
Topics: Aspirin; Chemistry, Pharmaceutical; Excipients; Lubrication; Particle Size; Pressure; Salicylates; Solubility; Tablets | 1978 |
Simple and rapid high-pressure liquid chromatographic simultaneous determination of aspirin, salicylic acid, and salicyluric acid in plasma.
Topics: Aspirin; Chromatography, High Pressure Liquid; Hippurates; Methods; Salicylates; Time Factors | 1978 |
Role of platelets in aspirin-sensitive bronchoconstriction in the guinea-pig; interactions with salicylic acid.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Arachidonic Acids; Aspirin; Blood Platelets; Bradykinin; Bronchi; Drug Synergism; Guinea Pigs; Platelet Aggregation; Salicylates | 1978 |
Quantitative estimation of salicylic acid and its metabolites by thin-layer densitometry.
Topics: Aspirin; Chromatography, Thin Layer; Densitometry; Humans; Salicylates; Time Factors | 1978 |
[Kinetics of salicylates from the blood to the articular fluid].
Topics: Arthritis; Aspirin; Humans; Salicylates; Synovial Fluid | 1978 |
Salicylate-induced hypoglycemia and ketoacidosis in a nondiabetic adult.
Topics: Acidosis; Aged; Alkalosis, Respiratory; Aspirin; Female; Glucose; Humans; Hypoglycemia; Infusions, Parenteral; Ketosis; Salicylates | 1978 |
Determination of salicylic acid and aspirin in multicomponent tablets by liquid chromatography on a nonionic resin.
Topics: Aspirin; Chromatography, Liquid; Drug Combinations; Methods; Salicylates; Tablets | 1978 |
Analysis for salicylic acid in serum by high-performance liquid chromatography.
Topics: Aspirin; Child; Chromatography, High Pressure Liquid; Humans; Infant; Microchemistry; Salicylates | 1978 |
Deafness due to plain and long-acting aspirin tablets.
Topics: Aged; Aspirin; Deafness; Delayed-Action Preparations; Female; Humans; Male; Middle Aged; Salicylates; Sex Factors; Tablets | 1978 |
Influence of food and fluid ingestion on aspirin bioavailability.
Topics: Adult; Aspirin; Biological Availability; Drinking; Eating; Food; Humans; Male; Models, Biological; Salicylates | 1978 |
Clinical pharmacokinetics of aspirin.
Topics: Absorption; Aspirin; Biotransformation; Child; Female; Humans; Infant, Newborn; Intestinal Absorption; Kinetics; Male; Maternal-Fetal Exchange; Pregnancy; Salicylates | 1978 |
Effects of concomitant aspirin administration on the pharmacokinetics of indomethacin in man.
Topics: Adult; Aspirin; Biotransformation; Drug Interactions; Half-Life; Humans; Indomethacin; Intestinal Absorption; Kinetics; Male; Salicylates; Statistics as Topic; Tissue Distribution | 1978 |
Strain differences in aspirin-induced gastric ulceration in rats.
Topics: Animals; Aspirin; Esterases; Gastric Juice; Gastric Mucosa; Hexosamines; Ions; Male; Prothrombin Time; Rats; Salicylates; Species Specificity; Stomach Ulcer | 1978 |
Relationship between inhibition of prostaglandin beta-oxidation and deenergization of mitochondrial membranes.
Topics: Animals; Aspirin; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chlorpromazine; Dinitrophenols; Imipramine; Indomethacin; Mitochondria, Liver; Mitochondrial Swelling; Oxidation-Reduction; Oxidative Phosphorylation; Prostaglandins E; Rats; Salicylates | 1978 |
Incidence and severity of experimental allergic encephalomyelitis and cerebral prostaglandin synthesis in essential fatty acid deficient and aspirin-treated rats.
Topics: Animals; Aspirin; Brain; Brain Chemistry; Encephalomyelitis, Autoimmune, Experimental; Fatty Acids, Essential; Male; Prostaglandins F; Rats; Salicylates | 1978 |
The finite dose technique as a valid in vitro model for the study of percutaneous absorption in man.
Topics: Aspirin; Benzoates; Caffeine; Chloramphenicol; Dinitrochlorobenzene; Hippurates; Humans; In Vitro Techniques; Models, Biological; Nicotinic Acids; Phenols; Salicylates; Skin Absorption; Urea | 1978 |
[Epidermopoietic action of toxically applied salicylic acids in animal experiments].
Topics: Animals; Aspirin; Cell Division; Dermatologic Agents; Dose-Response Relationship, Drug; Guinea Pigs; Hydrocortisone; Keratosis; Mitosis; Salicylates; Skin | 1978 |
Prostaglandins and aspirin: an alternative view.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyclooxygenase Inhibitors; Depression, Chemical; Humans; Prostaglandins; Rheumatic Diseases; Salicylates | 1975 |
Potentiation of the anti-inflammatory and analgesic activity of aspirin by caffeine in the rat.
Topics: Animals; Arthritis, Rheumatoid; Aspirin; Caffeine; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Indomethacin; Inflammation; Male; Phenylbutazone; Rats; Salicylates | 1976 |
The effects of salicylate and aspirin on the activity of phosphorylase a in perfused hearts of rats.
Topics: Animals; Aspirin; Glycogen; Heart; In Vitro Techniques; Lactates; Myocardium; Perfusion; Phosphorylases; Rats; Salicylates | 1977 |
Stability of aspirin in propoxyphene compound dosage forms.
Topics: Aspirin; Capsules; Dextropropoxyphene; Drug Combinations; Drug Stability; Drug Storage; Half-Life; Humidity; Salicylates; Time Factors | 1977 |
Aspirin-induced hepatotoxicity and its effect on juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Aspartate Aminotransferases; Aspirin; Chemical and Drug Induced Liver Injury; Child; Female; Humans; Liver; Male; Salicylates | 1977 |
Inhibition of glucosamine synthesis by salicylates, hydrocortisone and two non-ulcerogenic drugs.
Topics: Acetaminophen; Aspirin; Carbohydrate Epimerases; Duodenal Ulcer; Gastric Mucosa; Gentamicins; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Humans; Hydrocortisone; In Vitro Techniques; Intestinal Mucosa; Peptic Ulcer; Salicylates; Sodium Salicylate | 1977 |
Salicylic acid prevents inhibition by aspirin of arachidonic acid-induced hypotension, bronchoconstriction and thrombocytopenia [proceedings].
Topics: Animals; Arachidonic Acids; Aspirin; Blood Pressure; Bronchi; Guinea Pigs; In Vitro Techniques; Rabbits; Salicylates; Thrombocytopenia | 1977 |
Aspirin, salicylates, and the magic of diets.
Topics: Aspirin; Diet; Drug Hypersensitivity; Food Additives; Humans; Salicylates | 1977 |
Absorption, and effect on gastric mucosa, of buffered and non-buffered tablets of acetylsalicylic acid.
Topics: Aspirin; Buffers; Double-Blind Method; Gastric Mucosa; Humans; Intestinal Absorption; Salicylates; Stomach; Tablets; Time Factors | 1977 |
Pharmacokinetics of salicylate and indomethacin in coeliac disease.
Topics: Adult; Aspirin; Celiac Disease; Female; Humans; Indomethacin; Kinetics; Male; Middle Aged; Salicylates; Time Factors | 1977 |
Non-steroid anti-inflammatory drugs: combined assay for anti-edemic potency and gastric ulcerogenesis in the same animal.
Topics: Acacia; Adjuvants, Pharmaceutic; Animals; Aspartic Acid; Aspirin; Carrageenan; Diclofenac; Drug Evaluation, Preclinical; Edema; Female; Glucose; Glycyrrhiza; Male; Phenylacetates; Plants, Medicinal; Pyrroles; Rats; Salicylates; Stomach Ulcer; Tolmetin | 1977 |
Augmentation of human blood acetylsalicylate concentrations by the simultaneous administration of acetaminophen with aspirin.
Topics: Acetaminophen; Aspirin; Caffeine; Drug Combinations; Drug Interactions; Humans; Salicylates; Time Factors | 1977 |
Patterns of plasma concentrations and urinary excretion of salicylate in rheumatoid arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Drug Interactions; Female; Humans; Kinetics; Male; Middle Aged; Salicylates; Sex Factors; Time Factors | 1977 |
Determination of salicylic acid, acetylsalicylic anhydride and acetylsalicylsalicylic acid in acetylsalicylic acid by high performance liquid chromatography.
Topics: Aspirin; Chemistry, Pharmaceutical; Chromatography, Liquid; Quality Control; Salicylates | 1977 |
New experimental model for the primary evaluation of topical contra-inflammatory agents.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Body Temperature; Clobetasol; Croton Oil; Dermatitis, Contact; Drug Evaluation; Ear, External; Flumethasone; Hydrocortisone; Indomethacin; Rabbits; Salicylates; Skin | 1977 |
Pharmacokinetic and pharmacodynamic implications of long-term administration of non-steroidal anti-inflammatory agents.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Diclofenac; Drug Interactions; Female; Humans; Kinetics; Male; Salicylates; Time Factors | 1977 |
Methodology of kinetic interaction studies in clinical pharmacology: an experimental contribution on diftalone and acetylsalicylic acid.
Topics: Adult; Aspirin; Biological Availability; Drug Interactions; Half-Life; Humans; Kinetics; Male; Pyridazines; Salicylates; Time Factors | 1977 |
[Skin vasoconstriction effect of contact antiphlogistics].
Topics: Anti-Inflammatory Agents; Aspirin; Bufexamac; Humans; Hydrocortisone; Indomethacin; Oxyphenbutazone; Salicylates; Skin; Vasoconstriction | 1977 |
Failure of prednisone to alter plasma salicylate concentrations in dogs.
Topics: Animals; Aspirin; Dogs; Prednisone; Salicylates | 1976 |
Red cell organic phosphates during administration of salicylates.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aminosalicylic Acids; Aspirin; Diphosphoglyceric Acids; Erythrocytes; Female; Humans; Male; Middle Aged; Salicylates; Sodium Salicylate | 1976 |
Dermatopharmacology of salicylic acid. III. Topical contra-inflammatory effect of salicylic acid and other drugs in animal experiments.
Topics: Administration, Topical; Animals; Aspirin; Bufexamac; Dermatitis; Flumethasone; Fluocinolone Acetonide; Guinea Pigs; Hydrocortisone; Indomethacin; Male; Phenylbutazone; Salicylates | 1976 |
Effect of bases and accelerants on the anti-inflammatory activity of topical corticosteroids.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Drug Interactions; Guinea Pigs; Hydrocortisone; Indomethacin; Salicylates; Skin; Skinfold Thickness | 1976 |
The effects of antacids on enteric-coated salicylate preparations.
Topics: Adult; Antacids; Arthritis, Rheumatoid; Aspirin; Dyspepsia; Female; Humans; Male; Middle Aged; Salicylates; Tablets, Enteric-Coated; Time Factors | 1976 |
Intrauterine salicylate intoxication in a newborn. A case report.
Topics: Acetazolamide; Aspirin; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications; Salicylates | 1976 |
Application of gas-liquid chromatography and high-performance liquid chromatography to the analysis of trace amounts of salicylic acid, acetylsalicylic anhydride and acetylsalicylsalicylic acid in aspirin samples and aspirin formulations.
Topics: Anhydrides; Aspirin; Buffers; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Liquid; Salicylates; Solvents; Tablets | 1976 |
Acute poisoning with dextropropoxyphene. Clinical symptoms and plasma concentrations.
Topics: Acidosis; Acute Disease; Adolescent; Adult; Arrhythmia, Sinus; Aspirin; Barbiturates; Dextropropoxyphene; Drug Combinations; Ethanol; Female; Humans; Male; Middle Aged; Respiration Disorders; Salicylates; Time Factors; Ventricular Fibrillation | 1976 |
The variability of platelet-collagen interaction. Its influence on aspirin-induced inhibition of platelet aggregation.
Topics: Adolescent; Adult; Aspirin; Collagen; Esterases; Female; Humans; Male; Middle Aged; Platelet Adhesiveness; Platelet Aggregation; Salicylates; Sex Factors; Time Factors | 1976 |
Analgesics and the kidney: a community-based study.
Topics: Adult; Analgesics; Aspirin; Australia; Female; Humans; Kidney Diseases; Leukocytes; Male; Middle Aged; Osmolar Concentration; Salicylates; Substance-Related Disorders; Urine | 1976 |
[Comparison of serum and urinary salicylic acid levels following administration of Acylpyrin, Superpyrin, and Palaprin in man].
Topics: Adult; Aspirin; Humans; Middle Aged; Salicylates; Time Factors | 1976 |
Children with juvenile rheumatoid arthritis treated with salicylates for 15 days, with daily serum salicylate determinations.
Topics: Administration, Oral; Arthritis, Juvenile; Aspirin; Humans; Salicylates | 1976 |
[Subacute nonpurulent de Quervain's thyroiditis].
Topics: Adult; Aspirin; Female; Humans; Hydrocortisone; Male; Middle Aged; Prednisolone; Salicylates; Syndrome; Thyroiditis | 1976 |
[Side and toxic effects of salicylates].
Topics: Aspirin; Chemical and Drug Induced Liver Injury; Female; Heart Diseases; Humans; Kidney Diseases; Male; Pregnancy; Salicylates; Stomach Diseases | 1976 |
Salicylate- and aspirin-induced uncoupling of oxidative phosphorylation in mitochondria isolated from the mucosal membrane of the stomach.
Topics: Adenosine Diphosphate; Animals; Aspirin; Gastric Mucosa; Microscopy, Electron; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Salicylates; Swine; Uncoupling Agents | 1976 |
Inhibiting effect of feprazone on "in vitro" human platelet aggregation.
Topics: Adenosine Diphosphate; Anti-Inflammatory Agents; Aspirin; Collagen; Humans; In Vitro Techniques; Indomethacin; Phenylbutazone; Platelet Aggregation; Salicylates | 1976 |
Effects of different doses of acetylsalicylic acid on renal function in the dog.
Topics: Animals; Aspirin; Dogs; Female; Glomerular Filtration Rate; Kidney; Male; p-Aminohippuric Acid; Regional Blood Flow; Salicylates; Sodium | 1976 |
Salicylate therapy and drug interaction in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Aspirin; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Indomethacin; Male; Middle Aged; Salicylates | 1975 |
Evaluation of an enteric coated aspirin preparation.
Topics: Adult; Aspirin; Biological Availability; Drug Evaluation; Female; Humans; Intestinal Absorption; Male; Metoclopramide; Middle Aged; Salicylates; Saliva; Stimulation, Chemical; Stomach; Tablets, Enteric-Coated | 1976 |
Salicylates in saliva.
Topics: Administration, Oral; Adult; Aspirin; Female; Humans; Male; Protein Binding; Salicylates; Saliva | 1976 |
Drug interactions in the management of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Interactions; Drug Therapy, Combination; Humans; Indomethacin; Phenylbutazone; Prednisolone; Protein Binding; Salicylates | 1976 |
Does aspirin play a role in analgesic nephropathy?
Topics: Animals; Aspirin; Caffeine; Dehydration; Drug Combinations; Female; Hot Temperature; Humidity; Kidney Diseases; Kidney Papillary Necrosis; Male; Phenacetin; Rats; Salicylates | 1976 |
[Aspirin: its contraindication in oral surgery].
Topics: Aspirin; Hemostasis; Humans; Mouth; Pyrazoles; Salicylates | 1975 |
Suppression of lymphocyte transformation after aspirin ingestion.
Topics: Administration, Oral; Animals; Aspirin; B-Lymphocytes; Culture Media; Depression, Chemical; DNA; Erythrocytes; Humans; Immune Adherence Reaction; Lectins; Leukocyte Count; Lymphocyte Activation; Lymphocytes; Mitogens; Salicylates; Sheep; T-Lymphocytes; Thymidine; Time Factors; Tritium | 1975 |
[Serum salicylates in gastrointestinal hemorrhage].
Topics: Acute Disease; Adolescent; Adult; Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Hematemesis; Humans; Male; Melena; Middle Aged; Salicylates | 1976 |
The anti-inflammatory agents used in rheumatic disorders.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Anti-Inflammatory Agents; Antimalarials; Aspirin; Colchicine; Gold; Humans; Indomethacin; Phenylbutazone; Rheumatic Diseases; Salicylates | 1975 |
Interference with histamine and imidazole acetic acid metabolism by salicylates: a possible contribution to salicylate analgesic activity?
Topics: Adolescent; Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Histamine; Humans; Imidazoles; Mice; Middle Aged; Rats; Salicylates | 1976 |
Are all aspirins alike?
Topics: Antacids; Aspirin; Buffers; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Intestinal Absorption; Salicylates; Solubility; Solutions | 1976 |
Diseases causing end-stage renal failure in New South Wales.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Australia; Caffeine; Codeine; Cystoscopy; Female; Glomerulonephritis; Humans; Hypertension, Renal; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Phenacetin; Polycystic Kidney Diseases; Pyelonephritis; Renal Dialysis; Salicylamides; Salicylates; Transplantation, Homologous; Urography; Vesico-Ureteral Reflux | 1975 |
[Biopharmaceutical evaluation of some tablets of acetylsalicylic acid. Importance of the method of dissolution in the establishment of the in vivo and in vitro correlations].
Topics: Adult; Aspirin; Biopharmaceutics; Female; Humans; Male; Salicylates; Solubility; Tablets | 1975 |
Salicylate intoxication in infancy: a review.
Topics: Acidosis; Alkalosis; Alkalosis, Respiratory; Animals; Aspirin; Child; Child, Preschool; Dehydration; Fever; Humans; Hyperglycemia; Infant; Papio; Poisoning; Salicylates | 1975 |
[Osmotic laxatives and absorption of drugs from the intestine].
Topics: Adult; Aged; Aspirin; Humans; Intestinal Absorption; Lithium; Magnesium; Magnesium Sulfate; Middle Aged; Osmolar Concentration; Salicylates; Stimulation, Chemical | 1975 |
Immunogenicity of aryl esters of salicylic or acetylsalicylic acid in guinea pigs.
Topics: Acetylation; Anaphylaxis; Anhydrides; Animals; Aspirin; Carboxylic Acids; Cross Reactions; Dermatitis, Contact; Esters; Guinea Pigs; Immunization; Salicylates; Serum Albumin, Bovine | 1975 |
Studies on photopherapy in newborn infants. Influence on protein binding of bilirubin and salicylate and on activity of acetylsalicylic acid esterase.
Topics: Animals; Aspirin; Bilirubin; Blood Proteins; Esterases; Hematocrit; Humans; Infant, Newborn; Jaundice, Neonatal; Male; Phototherapy; Protein Binding; Rabbits; Salicylates; Serum Albumin | 1975 |
[A change in the sensitivity of the kidneys to antidiuretic hormone under the influence of several analgetic substances].
Topics: Animals; Aspirin; Diuresis; Dogs; Glomerular Filtration Rate; Kidney; Kidney Concentrating Ability; Male; Phenacetin; Salicylates; Vasopressins; Water-Electrolyte Balance | 1975 |
Letter: The clinical course of patients with analgesic nephropathy.
Topics: Analgesics; Aspirin; Caffeine; Codeine; Creatinine; Female; Follow-Up Studies; Humans; Kidney; Kidney Diseases; Pain; Phenacetin; Salicylates; Substance-Related Disorders | 1975 |
Aspirin dosages for the dog.
Topics: Administration, Oral; Animals; Aspirin; Dog Diseases; Dogs; Female; Male; Salicylates; Time Factors; Vomiting | 1975 |
Assessment of aspirin absorption rate from urinary excretion rate measurements.
Topics: Absorption; Aspirin; Computers; Half-Life; Humans; Kinetics; Salicylates | 1975 |
Comparison of analgesic effects of isosteric variations of salicylic acid and aspirin (acetylasalicylic acid).
Topics: Analgesics; Animals; Aspirin; Benzoates; Bradykinin; Isomerism; Lethal Dose 50; Male; ortho-Aminobenzoates; Pain; Rats; Salicylates; Sulfhydryl Compounds | 1975 |
Influence of particle size on rectal absorption of aspirin.
Topics: Adult; Aspirin; Biological Availability; Female; Humans; Intestinal Absorption; Male; Middle Aged; Oils; Particle Size; Rectum; Salicylates; Solubility; Suppositories; Time Factors | 1975 |
Contractile responses of the guinea-pig trachea in vitro: modification by prostaglandin synthesis-inhibiting drugs.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Animals; Anti-Inflammatory Agents; Aspirin; Barium; Depression, Chemical; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Potassium; Prostaglandin Antagonists; Prostaglandins E; Prostaglandins F; Salicylates; Serotonin; Trachea | 1975 |
[Dosage of salicylates in juvenile rheumatoid arthritis].
Topics: Adolescent; Arthritis, Juvenile; Aspirin; Child; Child, Preschool; Humans; Salicylates; Time Factors | 1975 |
Acute pulmonary edema and plasma kininogen consumption in the adrenaline-treated rat: inhibition by acetylsalicylic acid and resistance to salicylate and indomethacin.
Topics: Animals; Aspirin; Drug Resistance; Epinephrine; Indomethacin; Kininogens; Male; Pulmonary Edema; Rats; Salicylates | 1975 |
Aspirin and lymphocyte transformation.
Topics: Adult; Aspirin; Female; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Male; Salicylates; Time Factors | 1975 |
[Quantitative determination of the main metabolites of acetylsalicylic acid. 1. A method for the quantitative determination of salicylic acid and its metabolites. Studies in healthy individuals].
Topics: Adult; Aspirin; Gentisates; Glucuronates; Humans; Hydrolysis; Kidney Failure, Chronic; Methods; Salicylates; Spectrometry, Fluorescence | 1975 |
[Quantitative determination of the main metabolites of acetylsalicylic acid/2nd communication: the concentrations of salicylic acid and its metabolites in patients with renal insufficiency (author's transl)].
Topics: Adult; Aspirin; Blood Urea Nitrogen; Creatinine; Glucuronates; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Salicylates | 1975 |
[Studies on the absorption of certain slightly water soluble active principles from suspensions and tablets].
Topics: Animals; Aspirin; Female; Gastric Mucosa; Methylcellulose; Particle Size; Rats; Salicylates; Sodium Dodecyl Sulfate; Solubility; Stearates; Sulfamethazine; Suspensions; Tablets; Time Factors | 1975 |
Pharmacokinetics and dosage of aspirin in cattle.
Topics: Administration, Oral; Animals; Arthritis; Aspirin; Cattle; Cattle Diseases; Female; Hindlimb; Injections, Intravenous; Male; Salicylates; Sodium Salicylate | 1975 |
Acute liver failure and encephalopathy (Reye's syndrome?) during salicylate therapy.
Topics: Acute Disease; Adolescent; Aspirin; Brain Diseases; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Reye Syndrome; Salicylates | 1975 |
Proceedings: Inhibition of glucosamine synthetase by ulcerogenic and non-ulcerogenic drugs.
Topics: Acetaminophen; Animals; Aspirin; Carbohydrate Epimerases; Gentamicins; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Hydrocortisone; Rats; Salicylates | 1975 |
Determination of tolmetin in human plasma by GLC and spectrophotometric procedures.
Topics: Aspirin; Chromatography, Gas; Humans; Methods; Pyrroles; Salicylates; Spectrophotometry, Ultraviolet; Time Factors; Tolmetin | 1975 |
[Determination of blood salicylate levels in humans after intravenous and intramuscular administration of lysine acetylsalicylate].
Topics: Aspirin; Humans; Injections, Intramuscular; Injections, Intravenous; Lysine; Salicylates | 1975 |
Correlation of serum aspirin esterase activity and half-life of salicylic acid.
Topics: Adult; Aspirin; Half-Life; Humans; Male; Middle Aged; Salicylates; Time Factors | 1975 |
Interaction of indomethacin and acetylsalicylic acid as shown by the serum concentrations of indomethacin and salicylate.
Topics: Administration, Oral; Adult; Aged; Aspirin; Drug Interactions; Female; Half-Life; Humans; Indomethacin; Male; Middle Aged; Salicylates; Suppositories | 1975 |
The effect of magnesium sulfate on the absorption of acetylsalicylic acid and lithium carbonate from the human intestine.
Topics: Adult; Aged; Antidotes; Aspirin; Feces; Humans; Hypertonic Solutions; Intestinal Absorption; Isotonic Solutions; Lithium; Magnesium Sulfate; Middle Aged; Salicylates | 1975 |
Sexual differences in the metabolism of salicylates.
Topics: Animals; Aspirin; Cattle; Female; Lethal Dose 50; Male; Mice; Salicylates; Sex Factors; Time Factors | 1975 |
Prostaglandin E1 high affinity binding sites of rat thymocytes. Specificity and blockade by non-steroidal antiinflammatory drugs and localization in a plasma membrane-enriched fraction.
Topics: Animals; Aspirin; Binding Sites; Binding, Competitive; Cell Membrane; Female; In Vitro Techniques; Indomethacin; Kinetics; L-Lactate Dehydrogenase; Nucleotidases; Prostaglandins E; Prostaglandins E, Synthetic; Protein Binding; Rats; Salicylates; Structure-Activity Relationship; Thymus Gland | 1976 |
Salicylate-induced injury of pyruvate-kinase-deficient erythrocytes.
Topics: Adenosine Triphosphate; Anemia, Hemolytic; Aspirin; Erythrocytes; Glucose; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Hexoses; Humans; Mitochondria; Oxidative Phosphorylation; Pyruvate Kinase; Salicylates | 1976 |
Acute encephalopathy in siblings. Reye syndrome vs salicylate intoxication.
Topics: Aspirin; Brain; Brain Diseases; Child; Diagnosis, Differential; Female; Humans; Liver; Liver Diseases; Male; Pharyngitis; Reye Syndrome; Salicylates | 1976 |
Absorption and excretion of tolemetin in man.
Topics: Aspirin; Biological Availability; Blood Proteins; Dose-Response Relationship, Drug; Half-Life; Humans; Kinetics; Male; Protein Binding; Pyrroles; Salicylates; Tablets; Tolmetin | 1976 |
Influence of aspirin formulation and dose on concentration of total salicylate in rat kidney.
Topics: Animals; Aspirin; Buffers; Kidney; Male; Rats; Rats, Inbred Strains; Salicylates; Time Factors | 1976 |
Letter: Correlation of plateau serum salicylate with rate of salicylate metabolism.
Topics: Aspirin; Body Weight; Humans; Kinetics; Salicylates | 1976 |
Treatment of Kawasaki disease using the intravenous aspirin anti-inflammatory effect of salicylate.
Topics: Acute Disease; Aspirin; Child; Child, Preschool; Coronary Disease; Female; Humans; Infant; Inflammation; Infusions, Intravenous; Male; Mucocutaneous Lymph Node Syndrome; Retrospective Studies; Salicylates; Treatment Outcome | 1992 |
Modulation of leukocyte adhesion in rat mesenteric venules by aspirin and salicylate.
Topics: Animals; Aspirin; Cell Adhesion; Cell Movement; Leukocytes; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Splanchnic Circulation; Venules | 1992 |
Effects of aspirin on pathways of ion permeation in Necturus antrum: role of nutrient HCO3.
Topics: Acetates; Acetic Acid; Animals; Aspirin; Bicarbonates; Biological Transport; Cell Membrane; Gastric Mucosa; Hydrogen-Ion Concentration; In Vitro Techniques; Membrane Potentials; Microscopy, Electron; Necturus; Pyloric Antrum; Salicylates; Salicylic Acid; Water-Electrolyte Balance | 1992 |
Aspirin, acetaminophen and proton transport through phospholipid bilayers and mitochondrial membranes.
Topics: Acetaminophen; Animals; Anions; Aspirin; Biological Transport; Humans; Hydrogen-Ion Concentration; Intracellular Membranes; Lipid Bilayers; Mitochondria; Oxidative Phosphorylation; Permeability; Phospholipids; Protons; Reye Syndrome; Salicylates; Salicylic Acid; Uncoupling Agents | 1992 |
Determination of salicylic acid by HPLC in plasma and saliva from children with juvenile chronic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Aspirin; Child; Chromatography, High Pressure Liquid; Female; Humans; Male; Salicylates; Salicylic Acid; Saliva | 1992 |
The presence of specific IgE to salicyloyl and O-methylsalicyloyl in aspirin-sensitive patients.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Drug Hypersensitivity; Female; Humans; Immunoglobulin E; Male; Middle Aged; Radioallergosorbent Test; Salicylates; Salicylic Acid | 1992 |
The effect of antacid on aspirin pharmacokinetics in healthy Thai volunteers.
Topics: Adult; Aluminum Hydroxide; Aspirin; Biological Availability; Chromatography, High Pressure Liquid; Drug Interactions; Female; Hippurates; Humans; Magnesium Hydroxide; Male; Salicylates; Salicylic Acid; Thailand | 1992 |
Simultaneous spectrophotometric determination in solid phase of aspirin and its impurity salicylic acid in pharmaceutical formulations.
Topics: Aspirin; Drug Contamination; Salicylates; Salicylic Acid; Spectrophotometry | 1992 |
Bioavailability of two formulations of acetylsalicylic acid gums.
Topics: Adult; Aspirin; Biological Availability; Chewing Gum; Humans; Male; Salicylates; Salicylic Acid | 1992 |
Salicylate hydroxylation as an early marker of in vivo oxidative stress in diabetic patients.
Topics: Adult; Aspirin; Diabetes Mellitus, Type 1; Female; Gentisates; Humans; Hydroxybenzoates; Hydroxylation; Male; Oxidation-Reduction; Reactive Oxygen Species; Salicylates; Thiobarbiturates | 1992 |
Simultaneous high-performance liquid chromatographic determination of salicylates in whole blood, plasma and isolated erythrocytes.
Topics: Animals; Aspirin; Cells, Cultured; Chromatography, High Pressure Liquid; Erythrocytes; Gentisates; Hippurates; Hydroxybenzoates; Rabbits; Reproducibility of Results; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet | 1992 |
Evaluation of 2-(2-thiophenecarboxy)benzoic acid and related active metabolites in biological samples.
Topics: Animals; Aspirin; Benzoates; Chromatography, Liquid; Female; Hydrogen-Ion Concentration; Male; Naproxen; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet; Thiophenes; Tissue Distribution | 1992 |
Intrathecal injection of acetylsalicylic acid, salicylic acid and indomethacin depresses C fibre-evoked activity in the rat thalamus and spinal cord.
Topics: Afferent Pathways; Animals; Aspirin; Axons; Behavior, Animal; Female; Indomethacin; Injections, Spinal; Male; Nerve Fibers; Neurons; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Spinal Cord; Thalamus | 1992 |
Triflusal vs aspirin on the inhibition of human platelet and vascular cyclooxygenase.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Humans; In Vitro Techniques; Mesenteric Arteries; Muscle, Smooth, Vascular; Platelet Aggregation Inhibitors; Salicylates; Thromboxane B2 | 1992 |
Does an apple a day keep the cardiologist away?
Topics: Aspirin; Cardiovascular Diseases; Fruit; Humans; Salicylates | 1992 |
Significant role of aspirin use in patients with esophagitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Chromatography, High Pressure Liquid; Drug Utilization; Endoscopy, Gastrointestinal; Esophagitis; Esophagoscopy; Humans; Medical History Taking; Peptic Ulcer; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Salicylates | 1991 |
Effects of paracetamol and aspirin on neural activity of joint mechanonociceptors in adjuvant arthritis.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Epoprostenol; Lysine; Male; Mechanoreceptors; Neural Conduction; Neurons; Nociceptors; Pain; Rats; Rats, Inbred Strains; Salicylates; Sensory Thresholds; Tarsus, Animal | 1991 |
Action of some salicylate derivatives on in vitro platelet aggregation. Inhibitory and inhibition antagonistic effects.
Topics: Arachidonic Acid; Aspirin; Humans; In Vitro Techniques; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Salicylates; Structure-Activity Relationship | 1991 |
Disposition of single-dose intravenous and oral aspirin in children.
Topics: Absorption; Administration, Oral; Aspirin; Biological Availability; Buffers; Child, Preschool; Drug Administration Schedule; Half-Life; Humans; Infusions, Intravenous; Mucocutaneous Lymph Node Syndrome; Salicylates; Salicylic Acid | 1991 |
Simultaneous determination of acetylsalicylic and salicylic acids in human serum and aspirin formulations by second-derivative synchronous fluorescence spectrometry.
Topics: Aspirin; Humans; Salicylates; Salicylic Acid; Spectrometry, Fluorescence | 1991 |
Novel direct high-performance liquid chromatographic method for determination of salicylate glucuronide conjugates in human urine.
Topics: Administration, Oral; Aspirin; Chromatography, High Pressure Liquid; Glucuronates; Hippurates; Humans; Salicylates | 1991 |
Inhibition of lipoxygenase and prostaglandin endoperoxide synthase by anacardic acids.
Topics: Aspirin; Cyclooxygenase Inhibitors; Lipoxygenase Inhibitors; Plants; Salicylates | 1991 |
Misoprostol does not protect articular cartilage from salicylate-induced suppression of proteoglycan synthesis.
Topics: Alprostadil; Animals; Aspirin; Cartilage, Articular; Cells, Cultured; Culture Media; Dogs; Glycosaminoglycans; Humerus; Misoprostol; Salicylates; Salicylic Acid; Sodium Salicylate | 1991 |
Decrease of inorganic blood sulfate following treatment with selected antirheumatic drugs: potential consequence for articular cartilage.
Topics: Adult; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cartilage, Articular; Chloroquine; Diflunisal; Humans; Kinetics; Male; Mice; Mice, Inbred C57BL; Oxyphenbutazone; Phenylbutazone; Propionates; Salicylates; Sodium Salicylate; Sulfates | 1990 |
High-pressure liquid chromatographic evaluation of cyclic paracetamol-acetylsalicylate and its active metabolites with results of a comparative pharmacokinetic investigation in the rat.
Topics: Acetaminophen; Acetanilides; Animals; Aspirin; Biological Availability; Chromatography, High Pressure Liquid; Male; Rats; Rats, Inbred Strains; Reference Standards; Salicylates; Spectrophotometry, Ultraviolet; Tissue Distribution | 1990 |
Effects of triflusal and acetylsalicylic acid on microthrombi formation in experimental brain ischemia.
Topics: Animals; Aspirin; Brain Ischemia; Cerebral Arteries; Intracranial Embolism and Thrombosis; Male; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Salicylates | 1991 |
Inability to interpret toxic salicylate levels in patients taking aspirin and diflunisal.
Topics: Arthritis, Rheumatoid; Aspirin; Diflunisal; Female; Humans; Male; Middle Aged; Salicylates | 1991 |
[Pharmacokinetics of acetylsalicylic acid for the prophylaxis of cardiovascular pathology].
Topics: Adult; Aspirin; Cardiovascular Diseases; Delayed-Action Preparations; Female; Humans; Male; Salicylates; Salicylic Acid; Tablets, Enteric-Coated | 1991 |
[The physiologic disposition and pharmacokinetics of guaiacol acetylsalicylate in rats].
Topics: Animals; Aspirin; Female; Guaiacol; Male; Rats; Salicylates; Tissue Distribution | 1990 |
Topical irritation of the gastrointestinal tract.
Topics: Animals; Aspirin; Colon; Rabbits; Salicylates; Salicylic Acid | 1990 |
Salicylate, mefenamate, meclofenamate, and quinine on cochlear potentials.
Topics: Acetates; Aminooxyacetic Acid; Animals; Aspirin; Cochlea; Evoked Potentials, Auditory; Guinea Pigs; Meclofenamic Acid; Mefenamic Acid; ortho-Aminobenzoates; Quinine; Salicylates | 1990 |
Do salicylates and ascorbate increase the outer membrane permeability to hydrophobic antibiotics in Pseudomonas aeruginosa?
Topics: Ascorbic Acid; Aspirin; Cell Membrane Permeability; Deoxycholic Acid; Fusidic Acid; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Rifampin; Salicylates; Salicylic Acid | 1990 |
Effect of salicylates on antibiotic sensitivity.
Topics: Anti-Bacterial Agents; Aspirin; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Lactams; Proteus vulgaris; Pseudomonas aeruginosa; Quinolones; Random Allocation; Salicylates; Serratia marcescens | 1990 |
Effects of non-steroidal anti-inflammatory drugs on human neutrophil NADPH oxidase in both whole cell and cell-free systems.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell-Free System; Enzyme Activation; Humans; Indomethacin; Kinetics; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Salicylates; Salicylic Acid; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Aspirin potentiates prestimulated acid secretion and mobilizes intracellular calcium in rabbit parietal cells.
Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Aspirin; Biological Transport; Calcium; Cyclic AMP; Dinoprostone; Gastric Juice; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Inositol Phosphates; Rabbits; Receptors, Cell Surface; Salicylates; Salicylic Acid; Signal Transduction | 1990 |
Characterization of an internal-surface reversed-phase silica support for liquid chromatography and its application to assays of drugs in serum.
Topics: Aspirin; Blood Chemical Analysis; Chromatography, Liquid; Desipramine; Humans; Injections; Nortriptyline; Pharmaceutical Preparations; Salicylates; Silicon Dioxide | 1990 |
Effects of some non-steroidal anti-inflammatory drug copper complexes on polymorphonuclear leukocyte oxidative metabolism.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Copper; Free Radical Scavengers; In Vitro Techniques; Indomethacin; Luminescent Measurements; Male; Neutrophils; Oxidation-Reduction; Pleurisy; Rats; Rats, Inbred Strains; Salicylates; Superoxides | 1990 |
Comparative metabolism of high doses of aspirin in man and rat.
Topics: Adolescent; Adult; Animals; Aspirin; Female; Gentisates; Glucuronates; Hippurates; Humans; Kinetics; Male; Middle Aged; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1990 |
Determination of salicilic acid in saliva by high-performance liquid chromatography.
Topics: Aspirin; Biological Availability; Chromatography, High Pressure Liquid; Humans; Salicylates; Salicylic Acid; Saliva | 1990 |
Depletion of plasma glycine and effect of glycine by mouth on salicylate metabolism during aspirin overdose.
Topics: Administration, Oral; Adult; Aged; Aspirin; Drug Overdose; Female; Glycine; Glycylglycine; Hippurates; Humans; Male; Middle Aged; Salicylates; Salicylic Acid | 1990 |
Non-steroidal anti-inflammatory drug-copper complex modulation of polymorphonuclear leukocyte migration.
Topics: Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Movement; Chemotaxis, Leukocyte; Indomethacin; Molecular Structure; Neutrophils; Organometallic Compounds; Pleurisy; Rats; Salicylates | 1990 |
Repeated oral administration of activated charcoal for treating aspirin overdose in young children.
Topics: Administration, Oral; Aspirin; Charcoal; Dialysis; Half-Life; Humans; Infant; Magnesium Sulfate; Male; Salicylates; Salicylic Acid | 1990 |
Metabolism of aspirin after therapeutic and toxic doses.
Topics: Adolescent; Adult; Aged; Aspirin; Child; Dose-Response Relationship, Drug; Female; Hippurates; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Salicylates; Salicylic Acid | 1990 |
Gastric retention of enteric-coated aspirin tablets in beagle dogs.
Topics: Administration, Oral; Animals; Aspirin; Dogs; Female; Food; Gastric Mucosa; Male; Salicylates; Stomach; Tablets, Enteric-Coated | 1990 |
Nondestructive near-infrared analysis of intact tablets for determination of degradation products.
Topics: Aspirin; Chromatography, High Pressure Liquid; Mathematics; Salicylates; Salicylic Acid; Spectrophotometry, Infrared; Tablets | 1990 |
Drug treatments for relief of pain due to bone metastases.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bone Neoplasms; Delayed-Action Preparations; Dextropropoxyphene; Drug Therapy, Combination; Female; Humans; Morphine; Palliative Care; Salicylates | 1985 |
[Analysis of the antigenicity-producing structure of aspirin and its related compounds].
Topics: Adolescent; Adult; Aged; Aspirin; Child; Child, Preschool; Cross Reactions; Drug Hypersensitivity; Epitopes; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Salicylates; Structure-Activity Relationship | 1988 |
Time-course of aspirin and salicylate in ocular tissues of rabbits.
Topics: Animals; Aqueous Humor; Aspirin; Ciliary Body; Cornea; Eye; Half-Life; Injections, Intravenous; Iris; Lens, Crystalline; Male; Rabbits; Retina; Salicylates; Salicylic Acid; Tissue Distribution; Vitreous Body | 1989 |
Pharmacokinetics of aspirin and its application in canine veterinary medicine.
Topics: Animals; Arthritis, Rheumatoid; Aspirin; Dog Diseases; Dogs; Female; Male; Salicylates | 1989 |
Renal handling of aspirin in the rat.
Topics: Animals; Aspirin; In Vitro Techniques; Kidney; Male; Perfusion; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1989 |
Pharmacokinetics of salicylic acid following administration of aspirin tablets and three different forms of soluble aspirin in normal subjects.
Topics: Adult; Aspirin; Buffers; Humans; Lysine; Salicylates; Salicylic Acid; Solubility; Tablets | 1989 |
Detection and determination of salicylic acid impurity in aspirin tablet formulations' by high performance liquid chromatography.
Topics: Aspirin; Chromatography, High Pressure Liquid; Drug Compounding; Gastritis; Humans; Nigeria; Salicylates | 1989 |
Reduction by acetylsalicylic acid of paracetamol-induced hepatic glutathione depletion in rats treated with 4,4'-dichlorobiphenyl, phenobarbitone and pregnenolone-16-alpha-carbonitrile.
Topics: Acetaminophen; Animals; Aspirin; Cytochrome P-450 Enzyme System; Enzyme Induction; Gastric Mucosa; Glutathione; In Vitro Techniques; Liver; Male; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Salicylates | 1989 |
Benorylate hydrolysis by human plasma and human liver.
Topics: Acetaminophen; Aspirin; Chromatography, High Pressure Liquid; Cytosol; Esterases; Female; Humans; Hydrolysis; In Vitro Techniques; Liver; Male; Microsomes, Liver; Salicylates | 1989 |
Salicylate pharmacokinetics in patients with rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Aspirin; Humans; Hydrogen-Ion Concentration; Middle Aged; Salicylates | 1989 |
Lymphatic transport of salicylates in dogs.
Topics: Administration, Oral; Animals; Aspirin; Dogs; Injections, Intravenous; Lymph; Lymphatic System; Salicylates | 1989 |
[Use of aspirin in the primary prevention of vascular thrombi. A comparative study with other anti-aggregant drugs].
Topics: Animals; Aspirin; Dipyridamole; Dogs; Drug Evaluation; Drug Therapy, Combination; Platelet Aggregation Inhibitors; Salicylates; Thrombosis | 1989 |
Aspirin-induced gastric mucosal damage in dogs: protection by the prostanoid Ro 22-1327.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Dogs; Female; Gastric Acid; Gastric Mucosa; Gastroscopy; Male; Prostaglandins E; Salicylates; Stomach Ulcer | 1989 |
Decreased permeation of cephalosporins through the outer membrane of Escherichia coli grown in salicylates.
Topics: Aspirin; Bacterial Outer Membrane Proteins; Cell Membrane; Cephalosporins; Culture Media; Drug Resistance, Microbial; Escherichia coli; Hydrolysis; Salicylates | 1989 |
Aspirin versus nonacetylated salicylate.
Topics: Arthritis, Rheumatoid; Aspirin; Humans; Salicylates | 1989 |
Fatal iatrogenic salicylate intoxication in a long-term user of enteric-coated aspirin.
Topics: Aspirin; Humans; Iatrogenic Disease; Salicylates; Tablets, Enteric-Coated; Time Factors | 1989 |
Direct serum injection in micellar liquid chromatography. Recovery of serum proteins and assay of hydrophilic drugs.
Topics: Aspirin; Blood Proteins; Cephalosporins; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Humans; Salicylates | 1989 |
Prevention of the formation of arterial thrombi using different antiplatelet drugs: experimental study in dogs.
Topics: Animals; Aspirin; Dipyridamole; Dogs; Indium Radioisotopes; Platelet Aggregation Inhibitors; Salicylates; Scintillation Counting; Thrombosis | 1989 |
Arterial chemoreceptor involvement in salicylate-induced hyperventilation in rats.
Topics: Animals; Aspirin; Blood Pressure; Chemoreceptor Cells; Cyanides; Hyperventilation; Injections, Intravenous; Male; Neurons; Oxygen; Perfusion; Rats; Rats, Inbred Strains; Respiration; Respiratory Function Tests; Salicylates | 1989 |
Enteric-coated aspirin bezoar: elevation of serum salicylate level by barium study. Case report and review of medical management.
Topics: Aged; Aspirin; Barium Sulfate; Bezoars; Bicarbonates; Female; Humans; Radiography; Salicylates; Sodium; Sodium Bicarbonate; Stomach; Tablets, Enteric-Coated; Therapeutic Irrigation | 1987 |
Absence of mutagenic activity of benorylate, paracetamol and aspirin in the Salmonella/mammalian microsome test.
Topics: Acetaminophen; Animals; Aspirin; Biotransformation; Male; Microsomes, Liver; Mutagenicity Tests; Rats; Rats, Inbred Strains; Salicylates; Salmonella typhimurium | 1987 |
Prevention of aspirin-induced gastric mucosal injury by histamine H2 receptor antagonists: a crossover endoscopic and intragastric pH study in the dog.
Topics: Animals; Aspirin; Dogs; Female; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Gastroscopy; Histamine H2 Antagonists; Male; Salicylates; Salicylic Acid | 1987 |
Ocular distribution of aspirin and salicylate following systematic administration of aspirin to rabbits.
Topics: Animals; Aspirin; Eye; Injections, Intravenous; Male; Rabbits; Salicylates | 1988 |
Aloe vera, salicylic acid, and aspirin for burns.
Topics: Aloe; Animals; Aspirin; Burns; Guinea Pigs; Plants, Medicinal; Salicylates | 1989 |
Antiinflammatory action of salicylates: aspirin is not a prodrug for salicylate against rat carrageenin pleurisy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Cell Count; Carrageenan; Gas Chromatography-Mass Spectrometry; Leukocytes; Pleurisy; Prodrugs; Prostaglandins; Rats; Salicylates | 1989 |
Aspirin inhibits phospholipase C.
Topics: Annexins; Aspirin; Cycloheximide; Dactinomycin; Glycoproteins; Humans; Indomethacin; Salicylates; Type C Phospholipases | 1986 |
Effects of triflusal and acetylsalicylic acid on platelet aggregation in whole blood of diabetic patients.
Topics: Adult; Aspirin; beta-Thromboglobulin; Diabetes Mellitus, Type 1; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins F; Salicylates; Thromboxane B2 | 1988 |
Modes of action of aspirin-like drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Calcium; Cell Aggregation; Complement C5; Cyclic AMP; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Lymphocyte Activation; Neutrophils; Piroxicam; Prostaglandin Antagonists; Salicylates; Superoxides; Thiazines; Thromboxane A2 | 1985 |
Effects of aspirin, indomethacin, and sodium salicylate on human erythrocyte membranes as detected with electron spin resonance spectroscopy.
Topics: Aspirin; Blood Coagulation; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Female; Humans; Indomethacin; Kinetics; Male; Membrane Fluidity; Salicylates; Salicylic Acid; Sex Factors; Thermodynamics | 1985 |
Effect of triflusal and other salicylic acid derivatives on cyclic AMP levels in rat platelets.
Topics: Alprostadil; Animals; Aspirin; Blood Platelets; Cyclic AMP; Dipyridamole; Drug Interactions; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1986 |
Oxidation of salicylates by stimulated granulocytes: evidence that these drugs act as free radical scavengers in biological systems.
Topics: Aspirin; Benzoates; Benzoic Acid; Chloramines; Free Radicals; Granulocytes; Hydrogen Peroxide; Hydroxides; Hypochlorous Acid; Oxidation-Reduction; Salicylates; Salicylic Acid; Superoxides; Thiourea; Xanthine Oxidase; Xanthines | 1987 |
Role of lipoxygenase metabolism in platelet function: effect of aspirin and salicylate.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Aspirin; Blood Platelets; Collagen; Humans; Hydroxyeicosatetraenoic Acids; Lipoxygenase; Platelet Adhesiveness; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid; Thromboxane B2 | 1986 |
Relationship between structure and activity of aspirin-related compounds on the inhibition of in vitro platelet aggregation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Collagen; Drug Interactions; Humans; In Vitro Techniques; Platelet Aggregation; Salicylates; Structure-Activity Relationship | 1986 |
Two modes of analgesic action of aspirin, and the site of analgesic action of salicylic acid.
Topics: Analgesia; Animals; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Inflammation; Male; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1986 |
Pharmacokinetics of aspirin and salicylate in relation to inhibition of arachidonate cyclooxygenase and antiinflammatory activity.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Inflammation; Kinetics; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Salicylates; Thromboxane B2 | 1987 |
Salicylates inhibit PAF-acether-induced rat paw oedema when cyclooxygenase inhibitors are ineffective.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Aspirin; Cyclooxygenase Inhibitors; Dexamethasone; Edema; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salicylates; Sodium Salicylate | 1986 |
Protective effect of triflusal and acetylsalicylic acid against arachidonic acid induced cerebrovascular occlusion in anesthetized rats.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cerebrovascular Disorders; Electroencephalography; Male; Platelet Aggregation; Rats; Rats, Inbred Strains; Salicylates | 1987 |
Heterogeneity of changes on the disposition of aspirin in rats with CCl4-induced chronic liver damage.
Topics: Aniline Hydroxylase; Animals; Aspirin; Carbon Tetrachloride; Carboxylic Ester Hydrolases; Colchicine; Gentisates; Glucuronates; Glucuronosyltransferase; Hydroxybenzoates; Kinetics; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1987 |
Platelets, eicosanoids, and coronary vasospasm.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cattle; Coronary Vasospasm; Coronary Vessels; Eicosanoic Acids; Humans; In Vitro Techniques; Methysergide; Muscle, Smooth, Vascular; Prostaglandin Endoperoxides, Synthetic; Salicylates; Salicylic Acid; Vasoconstriction | 1987 |
Effects and interaction studies of triflusal and other salicylic derivatives on cyclooxygenase in rats.
Topics: Alprostadil; Animals; Aorta, Thoracic; Aspirin; Blood Platelets; Drug Interactions; In Vitro Techniques; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Vasodilator Agents | 1988 |
Selectivity of oral aspirin as an inhibitor of platelet vs. vascular cyclooxygenase activity is reduced by portacaval shunt in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Aspirin; Blood Platelets; Blood Vessels; Cyclooxygenase Inhibitors; Gastric Mucosa; Liver; Male; Portacaval Shunt, Surgical; Rats; Salicylates; Salicylic Acid; Thromboxane B2; Time Factors | 1988 |
Effects of salicylate vs. aspirin on renal prostaglandins and function in normal and sodium-depleted dogs.
Topics: Animals; Aspirin; Blood Pressure; Diet, Sodium-Restricted; Dogs; Female; Glomerular Filtration Rate; Kidney; Male; Meclofenamic Acid; Potassium; Prostaglandins; Renal Circulation; Salicylates; Salicylic Acid | 1988 |
Pharmacokinetics of low-dose oral modified release, soluble and intravenous aspirin in man, and effects on platelet function.
Topics: Administration, Oral; Adult; Aspirin; Female; Humans; Injections, Intravenous; Kinetics; Male; Middle Aged; Platelet Aggregation; Salicylates; Salicylic Acid; Thromboxane A2 | 1988 |
Does non-acetylated salicylate inhibit thromboxane biosynthesis in human platelets?
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Blood Platelets; Choline; Double-Blind Method; Humans; Male; Random Allocation; Salicylates; Thromboxanes | 1988 |
The effect of concurrent aspirin upon plasma concentrations of tenoxicam.
Topics: Adult; Aspirin; Drug Interactions; Female; Humans; Male; Piroxicam; Protein Binding; Salicylates; Salicylic Acid | 1988 |
Effect of intragastric pH on mucosal protective action of sucralfate.
Topics: Animals; Aspirin; Bile Acids and Salts; Gastric Mucosa; Hydrogen-Ion Concentration; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Sucralfate | 1988 |
[Reye's syndrome and salicylates].
Topics: Acetaminophen; Adolescent; Aspirin; Child; Humans; Reye Syndrome; Salicylates; Virus Diseases | 1988 |
Pharmacokinetics of enteric-coated aspirin and inhibition of platelet thromboxane A2 and vascular prostacyclin generation in humans.
Topics: Adult; Aspirin; Blood Platelets; Epoprostenol; Female; Humans; Kinetics; Salicylates; Salicylic Acid; Saphenous Vein; Tablets, Enteric-Coated; Thromboxane A2; Thromboxane B2 | 1987 |
[Which of the various acetylsalicylic acid preparations is the most appropriate in each indication? A pharmacokinetic study].
Topics: Adult; Aspirin; Chromatography, High Pressure Liquid; Drug Evaluation; Female; Humans; Male; Salicylates; Salicylic Acid; Time Factors | 1988 |
Molecular integrity of aspirin in relation to Reye's syndrome.
Topics: Adolescent; Aspirin; Child; Child, Preschool; Humans; Hydrogen-Ion Concentration; Hydrolysis; Infant; Research; Reye Syndrome; Salicylates; Salicylic Acid; Spectrophotometry | 1988 |
Nonlinear pharmacokinetics of aspirin in rats.
Topics: Animals; Aspirin; Biological Availability; Dose-Response Relationship, Drug; Liver; Male; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1988 |
Effects of administration route on pharmacokinetics of aspirin in the rabbit.
Topics: Animals; Aspirin; Infusions, Parenteral; Injections, Intravenous; Male; Rabbits; Salicylates; Salicylic Acid | 1988 |
Effects of non-steroidal anti-inflammatory drugs on rat gastric mucosal leukotriene C4 and prostanoid release: relation to ethanol-induced injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Eicosanoic Acids; Ethanol; Gastric Mucosa; In Vitro Techniques; Indomethacin; Male; Prostaglandins; Rats; Rats, Inbred Strains; Salicylates; SRS-A | 1988 |
Silymarin improves metabolism and disposition of aspirin in cirrhotic rats.
Topics: Animals; Aspirin; Carbon Tetrachloride Poisoning; Carboxylic Ester Hydrolases; Flavonoids; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Inbred Strains; Salicylates; Silymarin | 1988 |
The absorption of acetylsalicylic acid from an enteric-coated formulation and the inhibition of thromboxane formation.
Topics: Adult; Aspirin; Depression, Chemical; Female; Half-Life; Humans; Intestinal Absorption; Male; Salicylates; Salicylic Acid; Tablets; Tablets, Enteric-Coated; Thromboxane B2; Thromboxanes | 1988 |
Effect of triflusal and acetylsalicylic acid on platelet aggregation in human whole blood: influence of red blood cells and leukocytes.
Topics: Adult; Aspirin; Erythrocytes; Humans; In Vitro Techniques; Leukocytes; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Salicylates; Salicylic Acid | 1988 |
Inhibition by salicylates of urea synthesis by isolated rat hepatocytes and citrulline synthesis by isolated rat mitochondria: an effect independent of uncoupling.
Topics: Animals; Aspirin; Citrulline; Liver; Male; Mitochondria, Liver; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Urea | 1988 |
Aspirin disposition in rats acutely intoxicated with CCl4.
Topics: Animals; Aspirin; Carbon Tetrachloride Poisoning; Gentisates; Half-Life; Liver; Male; Rats; Rats, Inbred Strains; Salicylates | 1987 |
Prostaglandin E2 binding sites in porcine oxyntic mucosa: effects of salicylates.
Topics: Animals; Aspirin; Binding Sites; Dinoprostone; Female; Gastric Mucosa; Parietal Cells, Gastric; Prostaglandins E; Salicylates; Salicylic Acid; Swine; Tritium | 1986 |
Consideration of platelet effects in the selection of an anti-inflammatory agent.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Humans; Platelet Aggregation; Salicylates | 1987 |
An in situ experimental model in rabbits for the study of rectal absorption.
Topics: Animals; Aspirin; Indomethacin; Insulin; Intestinal Absorption; Kinetics; Male; Rabbits; Rectum; Salicylates; Salicylic Acid; Suppositories; Time Factors | 1986 |
Lowering of plasma isoxicam concentrations with acetylsalicylic acid.
Topics: Administration, Oral; Adult; Aged; Aspirin; Binding, Competitive; Drug Interactions; Humans; Kinetics; Male; Middle Aged; Piroxicam; Protein Binding; Salicylates; Salicylic Acid | 1986 |
Effect of clofibrate on lipid peroxidation in rats treated with aspirin and 4-pentenoic acid.
Topics: Animals; Aspirin; Clofibrate; Cytosol; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Lipid Metabolism; Lipid Peroxides; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Proteins; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Sulfhydryl Compounds | 1987 |
Salicylate toxicity in elderly patients with rheumatoid arthritis.
Topics: Adult; Age Factors; Aged; Arthritis, Rheumatoid; Aspirin; Central Nervous System Diseases; Dose-Response Relationship, Drug; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Salicylates; Tinnitus | 1987 |
The extracellular control of intracellular aspirin hydrolysis.
Topics: Aspirin; Binding, Competitive; Carboxylic Ester Hydrolases; Erythrocytes; Fatty Acids; Humans; Hydrolysis; In Vitro Techniques; Protein Binding; Salicylates; Serum Albumin | 1987 |
Salicyl phenolic glucuronide pharmacokinetics in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Female; Glucuronates; Humans; Kinetics; Male; Middle Aged; Salicylates; Salicylic Acid | 1987 |
The evolution of non-steroidal anti-inflammatory drugs and their mechanisms of action.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Humans; Inflammation; Salicylates; Salicylic Acid | 1987 |
[Relative bioavailability of 2 commercial preparations of aspirin].
Topics: Adult; Aspirin; Biological Availability; Female; Humans; Kinetics; Male; Salicylates | 1986 |
Presence of salicylic acid in standardbred horse urine and plasma after various feed and drug administrations.
Topics: Administration, Oral; Administration, Topical; Animal Feed; Animals; Aspirin; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Horses; Hydrogen-Ion Concentration; Salicylates | 1987 |
Corticosteroids-salicylate interaction in a case of juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Aspirin; Child; Drug Interactions; Drug Therapy, Combination; Humans; Kinetics; Male; Prednisone; Salicylates | 1987 |
Determination of aspirin and salicylic acid in uremic patients' plasma using reversed-phase high-performance liquid chromatography.
Topics: Aspirin; Chromatography, High Pressure Liquid; Humans; Salicylates; Salicylic Acid; Uremia | 1987 |
Comparison of the effect of acetylsalicylic acid on platelet function in male and female patients with ischemic stroke.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Brain Ischemia; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation; Salicylates; Salicylic Acid; Sex Factors; Thromboxane B2 | 1987 |
Serum salicylate levels in a breast fed infant.
Topics: Adult; Arthritis, Juvenile; Aspirin; Breast Feeding; Female; Humans; Infant; Milk, Human; Pregnancy; Salicylates; Salicylic Acid | 1987 |
Inhibition of platelet 5-HT secretion and of 5-HT induced vasoconstriction by paracetamol.
Topics: Acetaminophen; Adenosine Diphosphate; Aspirin; Blood Platelets; Humans; In Vitro Techniques; Platelet Aggregation; Salicylates; Salicylic Acid; Serotonin; Thromboxane A2; Vasoconstriction | 1987 |
Disposition of aspirin and its metabolites in the semen of man.
Topics: Adolescent; Adult; Aspirin; Hippurates; Humans; Male; Salicylates; Salicylic Acid; Semen | 1987 |
Determination of plasma aspirin and salicylic acid concentrations after low aspirin doses by high-performance liquid chromatography with post-column hydrolysis and fluorescence detection.
Topics: Aspirin; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Humans; Hydrogen-Ion Concentration; Hydrolysis; Salicylates; Salicylic Acid; Spectrometry, Fluorescence | 1987 |
Studies of platelet hyperactivity in patients with ischemic cerebrovascular diseases: IV. Determination of the optimal dosage of aspirin by measuring plasma salicylate level.
Topics: Aged; Aspirin; Blood Platelets; Brain Ischemia; Female; Humans; Male; Middle Aged; Salicylates; Salicylic Acid; Thromboxane B2 | 1987 |
Interaction by bendrofluazide with acetylsalicylic acid.
Topics: Adult; Aspirin; Bendroflumethiazide; Caffeine; Drug Interactions; Female; Humans; Hydrogen-Ion Concentration; Male; Natriuresis; Potassium; Salicylates; Time Factors | 1986 |
The metabolism of aspirin in man: a population study.
Topics: Adult; Aspirin; Biotransformation; Female; Glucuronates; Glycine; Hippurates; Humans; Hydrogen-Ion Concentration; Male; Salicylates; Salicylic Acid; Sex Factors | 1986 |
Effect of short-term aspirin therapy on glycosylated hemoglobin analysis.
Topics: Aspirin; Chromatography, Ion Exchange; Glycated Hemoglobin; Humans; Salicylates | 1986 |
Mechanisms of cell association of chloroquine to leucocytes.
Topics: Aspirin; Cell Survival; Chloroquine; Humans; Hydrogen-Ion Concentration; Indomethacin; Leukocytes; Mathematics; Neutrophils; Salicylates; Salicylic Acid; Temperature; Time Factors | 1986 |
Application of a radiotelemetric system to evaluate the performance of enteric coated and plain aspirin tablets.
Topics: Animals; Aspirin; Biological Availability; Blood Specimen Collection; Dogs; Injections, Intravenous; Kinetics; Male; Salicylates; Salicylic Acid; Tablets; Tablets, Enteric-Coated; Telemetry | 1986 |
Serum salicylate concentrations and endoscopic evaluation of the gastric mucosa in dogs after oral administration of aspirin-containing products.
Topics: Administration, Oral; Animals; Aspirin; Dogs; Female; Gastric Mucosa; Kinetics; Male; Salicylates; Time Factors | 1986 |
Influence of age, gender, and obesity on salicylate kinetics following single doses of aspirin.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aspirin; Body Weight; Female; Humans; Infusions, Parenteral; Kinetics; Male; Obesity; Salicylates; Salicylic Acid; Sex Factors | 1986 |
Influence of gender and oral contraceptive steroids on the metabolism of salicylic acid and acetylsalicylic acid.
Topics: Adult; Aspirin; Blood Proteins; Contraceptives, Oral, Hormonal; Female; Humans; Kinetics; Male; Protein Binding; Salicylates; Salicylic Acid; Sex Factors | 1986 |
Toxic interaction between acetazolamide and salicylate: case reports and a pharmacokinetic explanation.
Topics: Acetazolamide; Aged; Aged, 80 and over; Aspirin; Blood Proteins; Drug Interactions; Female; Humans; Kinetics; Male; Metabolic Clearance Rate; Protein Binding; Salicylates; Salicylic Acid | 1986 |
Inhibition of thromboxane formation in vivo and ex vivo: implications for therapy with platelet inhibitory drugs.
Topics: Adult; Aspirin; Blood Platelets; Humans; Imidazoles; Male; Metabolic Clearance Rate; Middle Aged; Platelet Count; Salicylates; Thromboxane A2; Thromboxane B2 | 1987 |
Salicylates and 12-lipoxygenase activity in human washed platelets.
Topics: Adult; Arachidonate 12-Lipoxygenase; Arachidonate Lipoxygenases; Aspirin; Blood Platelets; Chromatography, High Pressure Liquid; Gentisates; Humans; Hydroxybenzoates; In Vitro Techniques; Lipoxygenase Inhibitors; Salicylamides; Salicylates; Salicylic Acid | 1986 |
Effect of food on the absorption of enteric-coated aspirin: correlation with gastric residence time.
Topics: Absorption; Adult; Aspirin; Eating; Fasting; Female; Gastric Emptying; Hippurates; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Salicylates; Salicylic Acid; Tablets, Enteric-Coated | 1987 |
Aspirin in the treatment of chronic inflammatory arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Female; Humans; Male; Salicylates | 1987 |
Public Health Service study of Reye's syndrome and medications. Report of the main study.
Topics: Adolescent; Aspirin; Child; Child, Preschool; Epidemiologic Methods; Female; Humans; Male; Research Design; Respiratory Tract Infections; Reye Syndrome; Salicylates; United States; United States Public Health Service | 1987 |
Differential salicylate-aspirin interaction on vascular prostacyclin and platelet thromboxane synthesis in patients undergoing saphenectomy.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Drug Interactions; Female; Humans; Middle Aged; Salicylates; Salicylic Acid; Thromboxane B2; Varicose Veins; Veins | 1985 |
Salicylate antagonizes the antiinflammatory action of aspirin in the rat.
Topics: Animals; Aspirin; Carrageenan; Drug Antagonism; Edema; Kinetics; Male; Rats; Salicylates; Salicylic Acid | 1985 |
Effects of salsalate (nonacetylated salicylate) and aspirin on serum prostaglandins in humans.
Topics: Adult; Aspirin; Dinoprostone; Humans; Male; Prostaglandins E; Salicylates; Thromboxane B2 | 1985 |
Differences in the haemorrhagic toxicity of aspirin between rats and mice.
Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Gentisates; Hydroxybenzoates; Kaolin; Liver; Male; Mice; Mice, Inbred ICR; Organ Size; Partial Thromboplastin Time; Prothrombin Time; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Species Specificity; Time Factors | 1985 |
Gentisate, a salicylate metabolite with antioxidant properties.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arthritis, Rheumatoid; Aspirin; Biotransformation; Gentisates; Humans; Joint Diseases; Rats; Salicylates; Synovial Fluid | 1985 |
Acute effects of acetylsalicylic acid on renal and hepatic function in normal humans.
Topics: Adolescent; Adult; Alanine Transaminase; Albuminuria; Aspartate Aminotransferases; Aspirin; beta 2-Microglobulin; Female; Humans; Kidney; Liver; Male; Middle Aged; Proteinuria; Prothrombin Time; Salicylates; Salicylic Acid | 1985 |
Indomethacin and salicylate modulate effect of insulin on glucose kinetics in dogs.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Glucose; Dogs; Drug Interactions; Female; Gluconeogenesis; Glucose; Indomethacin; Insulin; Kinetics; Liver; Prostaglandin Antagonists; Prostaglandins; Salicylates; Salicylic Acid; Time Factors | 1985 |
Cyclooxygenase inhibitors affect Met-enkephalin- and acetylcholine-stimulated motility of the isolated rat colon.
Topics: Acetylcholine; Animals; Aspirin; Colon; Cyclooxygenase Inhibitors; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Enkephalin, Methionine; Gastrointestinal Motility; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1985 |
Endothelial cells produce a lipoxygenase derived chemo-repellent which influences platelet/endothelial cell interactions--effect of aspirin and salicylate.
Topics: Adenine; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cell Adhesion; Cells, Cultured; Endothelium; Female; Humans; Kinetics; Lipoxygenase; Phospholipids; Platelet Adhesiveness; Pregnancy; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid; Umbilical Veins | 1985 |
Gastric ulcer formation and cyclo-oxygenase inhibition in cat antrum follows parenteral administration of aspirin but not salicylate.
Topics: Animals; Aspirin; Cats; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Female; Histamine; Infusions, Parenteral; Male; Prostaglandins E; Salicylates; Salicylic Acid; Stomach Ulcer | 1985 |
Interaction of non-steroidal anti-inflammatory drugs on platelet cyclo-oxygenase and lipoxygenase activity.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Humans; Indomethacin; Kinetics; Lipoxygenase; Models, Biological; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid; Sulfinpyrazone | 1985 |
Bioavailability of sustained-release aspirin preparations.
Topics: Adult; Aspirin; Biological Availability; Delayed-Action Preparations; Humans; Male; Salicylates; Salicylic Acid; Time Factors | 1986 |
Plasma and synovial fluid concentrations of salicylic acid and its metabolites in patients with joint effusions.
Topics: Adult; Aged; Arthritis; Aspirin; Female; Gentisates; Hippurates; Humans; Hydroxybenzoates; Male; Middle Aged; Salicylates; Salicylic Acid; Synovial Fluid | 1985 |
Confirmation of serum salicylate levels in Reye's syndrome: a comparison between the Natelson colorimetric method and high performance liquid chromatography.
Topics: Ammonia; Aspirin; Child; Chromatography, High Pressure Liquid; Colorimetry; Humans; Reye Syndrome; Salicylates; Salicylic Acid | 1985 |
Plasma salicylate levels and platelet function after acute and chronic administration of slow-release acetylsalicylic acid (Monobeltin).
Topics: Adult; Aspirin; Blood Platelets; Delayed-Action Preparations; Hippurates; Humans; Male; Platelet Aggregation; Salicylates; Salicylic Acid; Time Factors | 1985 |
Inhibition of human platelet thromboxane generation by aspirin in the absence of measurable drug levels in peripheral blood.
Topics: Adult; Aspirin; Blood Platelets; Depression, Chemical; Humans; Male; Salicylates; Salicylic Acid; Thromboxanes | 1985 |
The effects of age and sex on the disposition of acetylsalicylic acid and its metabolites.
Topics: Adult; Age Factors; Aged; Aspirin; Biotransformation; Female; Hippurates; Humans; Male; Models, Biological; Salicylates; Salicylic Acid; Sex Factors | 1985 |
High-pressure liquid chromatographic analysis of paracetamol, caffeine and acetylsalicylic acid in tablets. Salicylic acid quantitation.
Topics: Acetaminophen; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Salicylates; Salicylic Acid; Tablets | 1985 |
Adult respiratory distress syndrome induced by salicylate toxicity.
Topics: Aspirin; Humans; Male; Middle Aged; Respiratory Distress Syndrome; Salicylates | 1985 |
[Hepatotoxicity of non-steroidal anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Child; Female; Humans; Indoles; Liver; Liver Function Tests; Male; Middle Aged; Phenylacetates; Phenylpropionates; Pyrazoles; Pyrroles; Salicylates; Sulindac | 1985 |
Determination of paracetamol, salicylic acid and acetyl salicylic acid in serum by high-performance liquid chromatography.
Topics: Acetaminophen; Aspirin; Chromatography, High Pressure Liquid; Humans; Salicylates; Salicylic Acid | 1985 |
A sensitive liquid chromatographic assay for plasma aspirin and salicylate concentrations after low doses of aspirin.
Topics: Adult; Aspirin; Chromatography, Liquid; Female; Humans; Kinetics; Male; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet | 1985 |
[The bioavailability of combination preparations of acetylsalicylic acid and codeine phosphate].
Topics: Administration, Oral; Adult; Aspirin; Biological Availability; Codeine; Drug Combinations; Hippurates; Humans; Injections, Intravenous; Kinetics; Salicylates; Salicylic Acid; Suppositories | 1985 |
Decomposition of aspirin in the solid state in the presence of limited amounts of moisture.
Topics: Acetates; Aspirin; Drug Stability; Humidity; Kinetics; Salicylates; Salicylic Acid; Solubility; Temperature; Time Factors; Water | 1985 |
Aspirin dosing using 15 grain enteric coated tablets.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Osteoarthritis; Salicylates; Salicylic Acid; Tablets, Enteric-Coated; Tinnitus | 1985 |
[Reaction kinetics of the dissolution of acetylsalicylic acid and salicylic acid in aqueous solution. I. pH and temperature dependence of salicylic acid decomposition].
Topics: Aspirin; Chemical Phenomena; Chemistry; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Salicylates; Salicylic Acid; Solubility; Thermodynamics | 1985 |
[Anti-platelet actions of salicylates: in vivo, ex vivo and in vitro effects of choline salicylate].
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Platelets; Calcium; Choline; Drug Combinations; In Vitro Techniques; Male; Mice; Platelet Aggregation; Respiration; Salicylates; Shock, Septic; Sodium Salicylate | 1985 |
Aspirin kinetics and inhibition of platelet thromboxane generation-relevance for a solution of the "aspirin dilemma".
Topics: Adult; Aspirin; Blood Platelets; Capsules; Humans; Kinetics; Male; Salicylates; Salicylic Acid; Tablets; Thromboxane B2 | 1985 |
Hydrolysis of acetylsalicylsalicylic acid and salicylsalicylic acid in aqueous solution.
Topics: Aspirin; Chromatography, High Pressure Liquid; Drug Stability; Hydrolysis; Salicylates; Solutions | 1985 |
Effect of antacids on salicylate kinetics.
Topics: Adult; Aluminum Hydroxide; Antacids; Aspirin; Drug Combinations; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kinetics; Magnesium Hydroxide; Male; Salicylates; Salicylic Acid; Silicic Acid | 1985 |
[Reaction kinetic study of the solvolysis of acetylsalicylic acid and salicylic acid in the liquid phase. II. Role of pharmaceutic adjuvants in the decomposition of salicylic acid].
Topics: Adjuvants, Pharmaceutic; Aspirin; Drug Stability; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Salicylates; Solubility; Temperature | 1985 |
The effect of ionization on partition coefficients and topical delivery.
Topics: Administration, Topical; Animals; Aspirin; Male; Mice; Mice, Hairless; Salicylates; Salicylic Acid; Solubility | 1985 |
Attenuation of aspirin analgesia by calcium loading in healthy subjects.
Topics: Adult; Analgesics; Aspirin; Calcium; Humans; Magnesium; Male; Phosphates; Salicylates; Salicylic Acid | 1985 |
The evaluation of patients with urticaria.
Topics: Angioedema; Aspirin; Cold Temperature; Coloring Agents; Dermatitis, Contact; Food Preservatives; Hot Temperature; Humans; Pressure; Salicylates; Sunlight; Tyramine; Urticaria; Vasculitis; Water; Yeasts | 1985 |
Reye syndrome update.
Topics: Aspirin; Health Education; Humans; Reye Syndrome; Salicylates; United States; United States Food and Drug Administration | 1985 |
Clinical-pharmacokinetic investigations of acetylsalicylic acid in cases of imminent premature delivery.
Topics: Amniotic Fluid; Aspirin; Female; Fetal Blood; Humans; Infant, Newborn; Kinetics; Obstetric Labor, Premature; Placenta; Pregnancy; Salicylates; Salicylic Acid; Time Factors | 1985 |
Effect of halofenate on binding of various drugs to human plasma proteins and on the plasma half-life of antipyrine in monkeys.
Topics: Acetamides; Animals; Anticholesteremic Agents; Antipyrine; Aspirin; Blood Proteins; Carbon Isotopes; Chlorothiazide; Clofibrate; Dicumarol; Digitoxin; Drug Interactions; Fluorine; Glycolates; Half-Life; Haplorhini; Humans; Hypolipidemic Agents; Indomethacin; Macaca; Phenothiazines; Phenylbutazone; Salicylates; Warfarin | 1972 |
Suppression of lymphocyte transformation by salicylates.
Topics: Animals; Arthritis, Infectious; Aspirin; Isotope Labeling; Lymphocyte Activation; Mycoplasma Infections; Rats; Salicylates; Sodium Salicylate; T-Lymphocytes; Thymidine | 1973 |
Letter: Salicylates and pregnancy.
Topics: Abortion, Threatened; Animals; Aspirin; Drug Antagonism; Drug Evaluation; Female; Fetus; Humans; Obstetric Labor, Premature; Pregnancy; Prostaglandin Antagonists; Rats; Salicylates; Sodium Salicylate; Uterus | 1974 |
The estimation of acetylsalicylic acid and salicylate in biological fluids by gas-liquid chromatography.
Topics: Aspirin; Chromatography, Gas; Colorimetry; Humans; Methods; Salicylates | 1973 |
Competitive binding of two drugs for a single binding site on albumin: a circular dichroic study.
Topics: Animals; Aspirin; Binding Sites; Cattle; Chemical Phenomena; Chemistry, Physical; Chlorpropamide; Circular Dichroism; Color; Hydrogen-Ion Concentration; Mathematics; Pentobarbital; Salicylates; Serum Albumin, Bovine; Spectrophotometry; Sulfacetamide; Sulfadiazine; Sulfathiazoles; Thiopental | 1973 |
Pharmacological modification of glutathione and NADP+ reduction.
Topics: Adult; Aging; Aspirin; Binding, Competitive; Chloramphenicol; Erythrocytes; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Reductase; Hexokinase; Humans; In Vitro Techniques; Infant, Newborn; Kinetics; Lactates; Methemoglobin; NADP; Oxidation-Reduction; Pentosephosphates; Salicylates | 1972 |
Effects of salicylates on human platelets.
Topics: Adenine Nucleotides; Aspirin; Blood Coagulation Tests; Blood Platelets; Blood Viscosity; Centrifugation; Collagen; Epinephrine; Humans; Microscopy, Electron; Salicylates; Sodium Salicylate; Thrombosis | 1968 |
Effect of salicylates on human platelets.
Topics: Adenine Nucleotides; Aspirin; Blood Platelets; Salicylates; Thrombin | 1968 |
Aspirins and enzymes.
Topics: Aspirin; Enzyme Inhibitors; Humans; Salicylates | 1968 |
Drugs which inhibit prostaglandin biosynthesis.
Topics: Acetaminophen; Antioxidants; Arachidonic Acids; Aspirin; Blood Platelets; Dronabinol; Fatty Acids; Hypertension; Indomethacin; Kinetics; Metals; Microsomes; Mixed Function Oxygenases; Oxidoreductases; Prostaglandin Antagonists; Prostaglandins; Salicylates; Species Specificity; Structure-Activity Relationship; Subcellular Fractions; Terminology as Topic; Time Factors | 1974 |
Acetylsalicylic acid intolerance.
Topics: Adult; Aged; Allergens; Animals; Antibodies; Antigens; Aspirin; Asthma; Chronic Disease; Drug Hypersensitivity; Female; Humans; Immune Sera; Immunization, Passive; Immunodiffusion; Immunoglobulins; Macaca mulatta; Male; Middle Aged; Radioimmunoassay; Salicylates; Skin Tests | 1974 |
[Significance of the benzene rings in protein binding of promazine and chlorpromazine].
Topics: Aspirin; Benzoates; Chemical Phenomena; Chemistry; Chlorpromazine; Nicotinic Acids; Phenothiazines; Promazine; Protein Binding; Salicylates; Serum Albumin, Bovine | 1969 |
Alteration in metabolism of acetylsalicylic acid in children with Down's syndrome: decreased plasma binding and formation of salicyluric acid.
Topics: Aspirin; Child; Child, Preschool; Down Syndrome; Erythrocytes; Female; Humans; Male; Pharmacogenetics; Salicylates; Uric Acid | 1970 |
[Study of salicylemia in vivo in the pre-ruminant calf after administration of different types of aspirin tablets].
Topics: Age Factors; Animals; Aspirin; Autoanalysis; Cattle; Intestinal Absorption; Salicylates | 1970 |
[Relationship between the inhibition of ATPase activity and inflammatory edema by nonsteroid anti-inflammatory drugs. Approach to the screening test in vitro of nonsteroid anti-inflammatory drugs].
Topics: Acetanilides; Adenosine Triphosphatases; Aminocaproates; Aminopyrine; Aminosalicylic Acids; Animals; Anti-Inflammatory Agents; Aspirin; Benzoates; Diphenhydramine; Edema; Flufenamic Acid; In Vitro Techniques; Male; Maleates; Mefenamic Acid; Mice; ortho-Aminobenzoates; Phenacetin; Quinine; Rabbits; Salicylates; Sarcolemma | 1970 |
Effect of anti-inflammatory compounds on actomyosin-adenosinetriphosphate interaction.
Topics: Actomyosin; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Aspirin; Benzene Derivatives; Calcium; Chemical Phenomena; Chemical Precipitation; Chemistry; Chlorine; Chloromercuribenzoates; Densitometry; Enzyme Activation; Flufenamic Acid; Hydrolysis; Indomethacin; Light; Magnesium; Mefenamic Acid; Muscle Contraction; Muscle Proteins; Muscle, Smooth; Organomercury Compounds; Phenols; Phenylacetates; Phenylbutazone; Propionates; Rabbits; Salicylates; Scattering, Radiation | 1970 |
[Continuous study in vivo of salicylemia in rabbits after ingestion of "soluble" aspirin in various galenic forms].
Topics: Animals; Aspirin; Dosage Forms; Powders; Rabbits; Salicylates; Tablets | 1969 |
[Continous in vivo study of blood salicylate in rabbits after ingestion of free and coated aspirin: influence of particle size].
Topics: Animals; Aspirin; Autoanalysis; Biopharmaceutics; Drug Compounding; Rabbits; Salicylates; Surface Properties; Time Factors | 1971 |
Proceedings: Kinetics of salicylate metabolism.
Topics: Arthritis, Rheumatoid; Aspirin; Back Pain; Glucuronates; Humans; Kinetics; Salicylates; Time Factors; Uric Acid | 1974 |
Inhibition of encephalomyocarditis virus replication by simple phosphonic and carboxylic acids.
Topics: Aminosalicylic Acids; Animals; Aspirin; Culture Techniques; Encephalomyocarditis virus; Mice; Organophosphonates; Salicylates; Virus Cultivation | 1965 |
Method of treatment of rheumatoid arthritis in different countries.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chloroquine; Dimethyl Sulfoxide; England; Europe; Flufenamic Acid; Gold; Humans; Indomethacin; Injections, Intra-Articular; Japan; ortho-Aminobenzoates; Oxyphenbutazone; Phenylbutazone; Prednisolone; Salicylates; South America; United States | 1966 |
Ultrastructural alterations of hepatic microbodies.
Topics: Anilides; Animals; Aspirin; Benzoates; Body Weight; Carcinoma, Hepatocellular; Kidney; Liver; Liver Neoplasms; Male; Mice; Microscopy, Electron; Organ Size; Organoids; Rats; Salicylates | 1966 |
Determination of free salicylic acid in buffered aspirin tablets.
Topics: Aspirin; Buffers; Chromatography; Drug Stability; Salicylates; Silicon Dioxide; Solubility; Spectrophotometry; Tablets; Ultraviolet Rays | 1968 |
Heterogeneous catalysis of aspirin degradation in chloroformic solution and its relationship to the determination of salicylic acid in buffered aspirin products.
Topics: Adsorption; Aluminum; Aspirin; Buffers; Carbonates; Catalysis; Chemistry, Pharmaceutical; Chloroform; Citrates; Drug Stability; Glycine; Kinetics; Magnesium; Salicylates; Silicon Dioxide; Solutions; Tablets | 1968 |
Studies on mechanism of action of salicylates. V. Effect of salicylic acid on enzymes involved in mucopolysaccharides synthesis.
Topics: Alcohol Oxidoreductases; Animals; Aspirin; Glucuronates; Glycosaminoglycans; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Lysosomes; NAD; Rabbits; Rats; Salicylates; Transferases; Uracil Nucleotides; Wound Healing | 1969 |
Interaction of salicylates with rat liver lysosomes.
Topics: Acetates; Acid Phosphatase; Animals; Aspirin; Electron Transport Complex IV; Esterases; Hydrogen-Ion Concentration; Liver; Lysosomes; Rats; Salicylates; Urate Oxidase | 1969 |
Analysis of phenylephrine and phenylpropanolamine hydrochlorides in combination.
Topics: Amino Alcohols; Aspirin; Chromatography, Thin Layer; Drug Combinations; Oxidation-Reduction; Periodic Acid; Phenethylamines; Phenylephrine; Phenylpropanolamine; Salicylates; Spectrum Analysis; Sympathomimetics; Ultraviolet Rays | 1971 |
Alveolar cell carcinoma associated with rheumatoid nodule.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adult; Arthritis, Rheumatoid; Aspirin; Bronchial Neoplasms; Female; Humans; Lung; Radiography; Rheumatoid Nodule; Salicylates | 1972 |
Effects of sodium salicylate and acetylsalicylic acid on cyclic 3',5'-AMP-dependent protein kinase.
Topics: Animals; Aspirin; Cattle; Cyclic AMP; Diaphragm; Histones; In Vitro Techniques; Kinetics; Muscles; Phosphates; Phosphorus Isotopes; Phosphotransferases; Protein Binding; Protein Kinases; Salicylates; Stimulation, Chemical | 1973 |
[Comparative study on quantitative determination of mixtures of analgesics. 1. Studies on selectivity of volumetric analysis procedures].
Topics: Acetaminophen; Aminopyrine; Analgesics; Ascorbic Acid; Aspirin; Barbiturates; Caffeine; Chlorpromazine; Codeine; Conductometry; Electrochemistry; Meprobamate; Mesylates; Methods; Papaverine; Phenacetin; Phenobarbital; Phenylbutazone; Potentiometry; Quinine; Salicylamides; Salicylates; Theobromine | 1974 |
The fibrinolytic activity of anti-inflammatory drugs.
Topics: Aminopyrine; Anti-Inflammatory Agents; Aspirin; Fibrinolysis; Flufenamic Acid; Humans; Mefenamic Acid; ortho-Aminobenzoates; Phenylbutazone; Salicylates | 1966 |
Inhibitory effect of salicylates and cinchophen derivatives on amino-acid incorporation.
Topics: Adenine; Amino Acids; Animals; Aspirin; Female; In Vitro Techniques; Leucine; Liver; Phenylalanine; Protein Biosynthesis; Quinolines; Rats; Ribosomes; Salicylates | 1967 |
[Experimentation in toxicology].
Topics: Animals; Aspirin; Barbiturates; Central Nervous System Stimulants; Drug Synergism; Imipramine; Poisoning; Salicylates | 1967 |
Therapy of acute salicylate ingestion.
Topics: Animals; Apomorphine; Aspirin; Charcoal; Child; Dogs; Gastric Lavage; Humans; Ipecac; Poisoning; Salicylates | 1969 |
Gastrointestinal absorption of two polymorphic forms of aspirin.
Topics: Aspirin; Humans; Intestinal Absorption; Salicylates; Thermodynamics | 1969 |
The inhibitory effect of non-steroidal anti-inflammatory agents on aggregation of red cells in vitro.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Sedimentation; Dextrans; Erythrocytes; Female; Fibrinogen; Flufenamic Acid; Gelatin; Glucocorticoids; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Male; Mefenamic Acid; Phenylbutazone; Rats; Salicylates | 1970 |
The actions of some non-steroidal drugs on lysosomes.
Topics: Acid Phosphatase; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Hydrocortisone; Lysosomes; Ovalbumin; Phenylacetates; Propionates; Rats; Salicylates; Temperature | 1970 |
Utilization of acetylsalicylic acid as sole carbon source and the induction of its enzymatic hydrolysis by an isolated strain of Acinetobacter lwoffii.
Topics: Aspirin; Hydrogen-Ion Concentration; Moraxella; Salicylates; Water | 1970 |
Further evidence on the question of polymorphism in aspirin.
Topics: Aspirin; Crystallization; Crystallography; Methods; Salicylates | 1971 |
Quantitation of thermography in arthritis using multi-isothermal analysis. II. Effect of nonsteroidal anti-inflammatory therapy on the thermographic index.
Topics: Acetaminophen; Acetanilides; Administration, Oral; Arthritis, Rheumatoid; Aspirin; Foot; Gout; Hand; Humans; Indomethacin; Injections, Intra-Articular; Knee; Prednisolone; Salicylates; Thermography | 1974 |
Simultaneous GLC estimation of salicylic acid and aspirin in plasma.
Topics: Aspirin; Chromatography, Gas; Cold Temperature; Drug Storage; Fluorides; Humans; Hydrolysis; Indicators and Reagents; Mass Spectrometry; Salicylates; Solvents; Spectrophotometry, Infrared; Temperature | 1974 |
Relationship between dose and apparent volume of distribution of salicylate in children.
Topics: Adolescent; Aspirin; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Kinetics; Male; Models, Biological; Salicylates | 1974 |
Evaluation of dimethylpolysiloxane fluids as vehicles for various pharmaceuticals. I: effect on stability and dissolution of aspirin.
Topics: Aspirin; Chemical Phenomena; Chemistry; Drug Stability; Pharmaceutical Vehicles; Salicylates; Silicones; Solubility; Spectrophotometry, Ultraviolet; Time Factors; Viscosity | 1974 |
Chromatographic identification of salicylic acid derivatives using polyamide thin-layer slides, ion-exchange and ordinary cellulose paper.
Topics: Aminosalicylic Acids; Aspirin; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Forensic Medicine; Salicylamides; Salicylates | 1974 |
Aspirin-ibuprofen interaction in the adjuvant-induced polyarthritic rat.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Interactions; Freund's Adjuvant; Male; Phenylpropionates; Rats; Salicylates; Time Factors | 1974 |
[Compounds of some drugs with poly(vinylpyrrolidone)].
Topics: Aminopyrine; Aspirin; Drug Compounding; Nicotinic Acids; Povidone; Salicylates; Sulfathiazoles; Vitamin K | 1974 |
Effect of phenacetin on the uptake and elimination of salicylate by the rat.
Topics: Administration, Oral; Animals; Aspirin; Carbon Radioisotopes; Depression, Chemical; Gastric Mucosa; Gastrointestinal Motility; Intestinal Mucosa; Kidney; Male; Phenacetin; Rats; Salicylates | 1974 |
[Effect of some drugs and excipients on the absorption of acetylsalicylic acid].
Topics: Animals; Aspirin; Humans; Pharmaceutic Aids; Rabbits; Salicylates | 1974 |
Factors influencing absorption and excretion of drugs. III. Effect of fasting on absorption and excretion of sodium salicylate and aspirin in rabbits.
Topics: Ammonium Chloride; Animals; Aspirin; Fasting; Gastric Mucosa; Male; Rabbits; Salicylates | 1974 |
Inhibition by aspirin of ribose conjugation in the metabolism of histamine.
Topics: Acetates; Adolescent; Adult; Animals; Anti-Inflammatory Agents; Aspirin; Carbon Radioisotopes; Chromatography, Thin Layer; Estrone; Female; Glucuronates; Histamine; Humans; Imidazoles; Male; Middle Aged; Morphine; Nucleotides; Rats; Ribose; Salicylates; Time Factors; Tritium | 1974 |
[Qualitative chromatographic determination of the conjugates of salicylic and salicyluric acids in blood plasma and urine].
Topics: Aspirin; Chromatography, Thin Layer; Glucuronates; Glycine; Humans; Hydrolysis; Kidney Failure, Chronic; Salicylates | 1974 |
The influence of acetylsalicyclic acid on the binding of acetrizoate to human albumin.
Topics: Acetrizoic Acid; Acetylation; Aspirin; Autoradiography; Binding Sites; Blood Protein Electrophoresis; Carbon Radioisotopes; Chromatography, Thin Layer; Dialysis; Drug Interactions; Half-Life; Humans; Hydrogen-Ion Concentration; Iodine Radioisotopes; Peptides; Protein Binding; Salicylates; Serum Albumin | 1973 |
New salicylates.
Topics: Animals; Arthritis, Rheumatoid; Aspirin; Diatrizoate; Gastrointestinal Hemorrhage; Humans; Platelet Adhesiveness; Rats; Salicylates; Sorbitol | 1972 |
Effects of salicylates on the canine stomach: a morphological and histochemical study.
Topics: Administration, Oral; Animals; Aspirin; Autopsy; Autoradiography; Biopsy; Body Weight; Dogs; Epithelial Cells; Gastric Mucosa; Gastrointestinal Hemorrhage; Histocytochemistry; Mucins; Salicylates; Stomach; Stomach Ulcer; Time Factors | 1972 |
[Harmful effects of common drugs on the visual apparatus. Minor analgesics, antipyretics, nonsteroid anti-inflammatory and antirheumatic drugs].
Topics: Analgesics; Anti-Inflammatory Agents; Antimalarials; Aspirin; Color Vision Defects; Corneal Opacity; Dimethyl Sulfoxide; Diplopia; Edema; Electrooculography; Electroretinography; Eye Diseases; Humans; Indoles; Nicotinic Acids; Optic Atrophy; Peptide Hydrolases; Pyrazoles; Retinal Hemorrhage; Salicylates; Vision Disorders | 1972 |
Benoral, Safapryn and Levius.
Topics: Acetaminophen; Acetanilides; Acetates; Aspirin; Humans; Rheumatic Diseases; Salicylates | 1972 |
The effect of anti-inflammatory drugs on parturition parameters in the rat.
Topics: Acetates; Animals; Aspirin; Cortisone; Depression, Chemical; Female; Fetal Death; Gestational Age; Labor, Obstetric; Male; Phenobarbital; Postpartum Hemorrhage; Pregnancy; Rats; Salicylates; Sodium Salicylate; Time Factors | 1973 |
Gastrointestinal blood loss during prolonged aspirin administration.
Topics: Administration, Oral; Adult; Aspirin; Chromium Radioisotopes; Drug Tolerance; Female; Gastrointestinal Hemorrhage; Humans; Male; Occult Blood; Salicylates; Time Factors | 1973 |
Observations on drug prescribing in rheumatoid arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Drug Prescriptions; Dyspepsia; Family Practice; Female; Gastrointestinal Hemorrhage; Humans; Indomethacin; Male; Middle Aged; Phenylbutazone; Prednisone; Salicylates; Scotland | 1974 |
Letter: Naproxen (naprosyn) and gastrointestinal haemorrhage.
Topics: Acetanilides; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Blood Transfusion; Female; Gastritis; Gastrointestinal Hemorrhage; Hematemesis; Humans; Male; Melena; Methyl Ethers; Middle Aged; Naphthalenes; Propionates; Salicylates | 1974 |
[Gastro-duodenal tolerance of some drugs with analgesic effect. Clinico-endoscopic considerations].
Topics: Analgesics; Anti-Inflammatory Agents; Antimalarials; Aspirin; Digestive System; Duodenal Ulcer; Esophagoscopy; Gastritis; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Gastroscopy; Glycols; Humans; Indomethacin; ortho-Aminobenzoates; Phenylbutazone; Pyrazoles; Quinolines; Salicylates; Stomach Ulcer | 1974 |
Interaction of salicylic acid with adenosine and adenosine triphosphate: potential mechanism of intensifying aspirin-induced GI blood loss.
Topics: Adenosine; Adenosine Triphosphate; Aspirin; Chemical Phenomena; Chemistry; Drug Interactions; Gastrointestinal Hemorrhage; Hydrogen-Ion Concentration; Kinetics; Platelet Aggregation; Salicylates; Spectrophotometry, Ultraviolet | 1974 |
[Salicylates and occult hemorrhages in the gastro-intestinal tract].
Topics: Animals; Aspirin; Benzidines; Drug Combinations; Drug Hypersensitivity; Feces; Gastrointestinal Hemorrhage; Guaiac; Guinea Pigs; Lithium; Mice; Occult Blood; Quinine; Rabbits; Rats; Salicylates | 1974 |
[Pharmacological properties of derivatives of ortho-oxybenzoic (salicylic) acid (review of the literature)].
Topics: Anti-Inflammatory Agents; Aspirin; Blood Pressure; Humans; Hydrocortisone; Intestinal Absorption; Kallikreins; Oxidation-Reduction; Oxidative Phosphorylation; Pituitary-Adrenal System; Rheumatic Diseases; Salicylamides; Salicylates; Sodium Salicylate | 1974 |
The antipyretic effect of pyrazolone derivatives and salicylates on fever induced with leukocytic or bacterial pyrogen.
Topics: Analgesics; Animals; Antipyrine; Aspirin; Central Nervous System; Drug Antagonism; Escherichia coli; Fever; Goats; In Vitro Techniques; Leukocytes; Lipopolysaccharides; Methylamines; Phenylbutazone; Pyrazoles; Pyrogens; Rabbits; Salicylates; Salmonella typhimurium; Sulfonic Acids | 1972 |
[Clinical pharmacology of common analgesics, narcotics and sedatives (tranquilizers)].
Topics: Acetaminophen; Analgesics; Aspirin; Barbiturates; Chloral Hydrate; Diazepam; Drug Synergism; Humans; Hypnotics and Sedatives; Limbic System; Meprobamate; Phenacetin; Phenobarbital; Salicylates; Secobarbital; Tranquilizing Agents | 1972 |
Evidence for a sex-linked difference in aspirin metabolism.
Topics: Adult; Aspirin; Esterases; Female; Humans; Male; Salicylates; Sex Factors; Time Factors | 1972 |
The first Walter Bradford Cannon lecture before the Society of Gastro-intestinal Radiologists.
Topics: Animals; Aspirin; Bile; Blood Proteins; Digestion; Dogs; Gastric Mucosa; Histamine Release; History, 19th Century; History, 20th Century; Humans; Hydrogen-Ion Concentration; Radiology; Receptors, Cholinergic; Salicylates; Societies, Medical; Stomach Ulcer; United States | 1973 |
Pulmonary edema and salicylate intoxication.
Topics: Adult; Aspirin; Blood Pressure; Cardiac Catheterization; Diagnosis, Differential; Female; Furosemide; Humans; Poisoning; Positive-Pressure Respiration; Pulmonary Artery; Pulmonary Edema; Radiography; Salicylates; Self Medication | 1974 |
Biochemical mechanisms of salicylate teratology in the rat.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Carbon Isotopes; Edetic Acid; Female; Fetus; Iron; Iron Isotopes; Manganese; Maternal-Fetal Exchange; Pregnancy; Radioisotopes; Rats; Salicylates; Time Factors; Zinc; Zinc Isotopes | 1973 |
Effect of intravenous salicylates on the gastric mucosal barrier in man.
Topics: Acid-Base Equilibrium; Administration, Oral; Adult; Aspirin; Atropine; Biological Transport; Cell Membrane Permeability; Diffusion; Female; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Inhalation; Injections, Intravenous; Intestinal Absorption; Male; Salicylates; Sodium; Time Factors | 1972 |
The absorption and metabolism in man of 4-acetamidophenyl-2-acetoxybenzoate (benorylate).
Topics: Acetaminophen; Acetanilides; Acetates; Analgesics; Aspirin; Chromatography, Thin Layer; Humans; Hydrogen-Ion Concentration; Hydrolysis; Intestinal Absorption; Kinetics; Salicylates; Suspensions; Tablets; Time Factors | 1972 |
Effects of various medications on values from the HABA and BCG methods for determining albumin.
Topics: Aspirin; Azo Compounds; Benzoates; Bromine; Cresols; Evaluation Studies as Topic; Freeze Drying; Humans; Indicators and Reagents; Methods; Phenobarbital; Phenols; Salicylates; Serum Albumin; Sulfisoxazole; Sulfonic Acids | 1972 |
Ion transport and surface ultrastructure in the non-secreting stomach. Effects of some weak acids and large osmolality variations.
Topics: Acetates; Animals; Aspirin; Biological Transport; Carbon Isotopes; Cats; Cell Membrane Permeability; Gastric Acidity Determination; Gastric Mucosa; Hydrochloric Acid; Lactates; Microscopy, Electron, Scanning; Osmolar Concentration; Potassium; Salicylates; Sodium; Sodium Chloride; Spectrophotometry; Water-Electrolyte Balance | 1972 |
The effect of aspirin on the response to endotoxin.
Topics: Animals; Aspirin; Biological Assay; Blood Cell Count; Blood Platelets; Blood Pressure; Cats; Central Venous Pressure; Depression, Chemical; Dogs; Female; Half-Life; Male; Rats; Salicylates; Secretory Rate; Serotonin; Sheep; Shock, Septic; Stomach | 1972 |
GLC analysis of aspirin from solid dosage forms.
Topics: Aspirin; Chromatography, Gas; Dosage Forms; Methods; Powders; Salicylates; Tablets | 1972 |
Induced optical activity following the binding of warfarin, indomethacin, 4-hydroxycoumarin and salicylic acid to human serum albumin.
Topics: Aspirin; Binding Sites; Circular Dichroism; Coumarins; Humans; Hydrogen-Ion Concentration; Indomethacin; Kinetics; Protein Binding; Salicylates; Serum Albumin; Warfarin | 1972 |
Studies on the metabolic mechanisms in aspirin-induced thrombocytopathy.
Topics: Adenosine Triphosphate; Aspirin; Binding, Competitive; Blood Platelet Disorders; Blood Platelets; Carbon Radioisotopes; Citric Acid Cycle; Decarboxylation; Depression, Chemical; Dose-Response Relationship, Drug; Glucose; Glycogen; Glycolysis; Hexokinase; Humans; In Vitro Techniques; Lactates; Oxygen Consumption; Protein Binding; Salicylates; Serum Albumin; Temperature | 1972 |
[Treatment of rheumatic disease in childhood without disturbing the liver function].
Topics: Administration, Oral; Arthritis, Rheumatoid; Aspirin; Child; Choline; Female; Humans; Male; Rheumatic Fever; Salicylates | 1973 |
Determination of total salicylates, phenacetin and-or total N-acetyl-p-aminophenol, and caffeine in biological samples and analgesic formulations.
Topics: Acids; Analgesics; Animals; Aspirin; Caffeine; Chloroform; Chromatography, Gas; Drug Interactions; Hydrolysis; Kidney; Male; Phenacetin; Phenols; Powders; Rats; Salicylates; Tablets; Time Factors | 1973 |
Salicylate poisoning.
Topics: Adult; Aspirin; Female; Fetal Death; Humans; Poisoning; Pregnancy; Pregnancy Complications; Salicylates | 1973 |
Analgesics and other drugs for relief of pain.
Topics: Analgesics; Aspirin; Azepines; Carbamazepine; Codeine; Dextropropoxyphene; Humans; Indomethacin; Methadone; Morphine; Narcotics; Pain; Pentazocine; Pyrazoles; Salicylates; Substance-Related Disorders | 1973 |
Simplified fluorometric determination of salicylate.
Topics: Aspirin; Colorimetry; Humans; Magnesium; Salicylates; Spectrometry, Fluorescence | 1973 |
Fatal poisoning from salt used as an emetic.
Topics: Aspirin; Blood Glucose; Blood Urea Nitrogen; Central Nervous System Diseases; Child, Preschool; Chlorides; Emetics; Gastric Lavage; Humans; Hypernatremia; Hypertonic Solutions; Male; Poisoning; Salicylates; Sodium; Sodium Chloride | 1973 |
Metabolism of aspirin in rumen and corpus tissues of rat stomach during first four minutes after administration.
Topics: Animals; Aspirin; Autoradiography; Carbon Isotopes; Chromatography, Thin Layer; Gastric Juice; Gastric Mucosa; Hydrolysis; Male; Rats; Rumen; Salicylates; Uric Acid | 1973 |
Stability of aspirin in liquid and semisolid bases. I. Substituted and nonsubstituted polyethylene glycols.
Topics: Acetylation; Aspirin; Drug Stability; Glycols; Polyethylenes; Salicylates; Spectrophotometry, Ultraviolet; Temperature; Time Factors | 1973 |
Salicylism, hyperventilation, and the central nervous system.
Topics: Acidosis, Respiratory; Animals; Aspirin; Blood-Brain Barrier; Brain; Carbon Dioxide; Dogs; Humans; Hydrogen-Ion Concentration; Hyperventilation; Infant; Male; Oxygen; Respiratory Center; Salicylates | 1973 |
Effects of salicylates on blood changes in mycoplasma arthritis in rats.
Topics: Animals; Antigens, Bacterial; Arthritis; Aspirin; Blood Cell Count; Blood Sedimentation; Complement System Proteins; Erythrocytes; Leukocyte Count; Male; Muramidase; Mycoplasma; Mycoplasma Infections; Rats; Salicylates; Time Factors | 1973 |
Toxicity of benorylate.
Topics: Acetanilides; Acetates; Analgesics; Aspirin; Humans; Salicylates | 1973 |
Nonsolvolytic acetylation of homatropine by aspirin.
Topics: Acetylation; Aspirin; Chemistry, Pharmaceutical; Chromatography, Gas; Half-Life; Kinetics; Magnetic Resonance Spectroscopy; Salicylates; Solubility; Temperature; Tropanes | 1973 |
The binding of salicylic acid and acetylsalicylic acid to human serum albumin.
Topics: Aspirin; Binding Sites; Carbon Isotopes; Chromatography, Gel; Dialysis; Humans; Protein Binding; Salicylates; Serum Albumin; Spectrometry, Fluorescence | 1973 |
Lowering of plasma concentrations of (+)-6-methoxy-alpha-methyl-2-naphthaleneacetic acid (naproxen) by aspirin in rats.
Topics: Administration, Oral; Animals; Aspirin; Blood Proteins; Carbon Isotopes; Drug Interactions; In Vitro Techniques; Injections, Intraperitoneal; Injections, Intravenous; Male; Methyl Ethers; Naphthalenes; Propionates; Protein Binding; Rats; Salicylates; Time Factors; Tritium | 1973 |
Fluorescent properties of bovine serum albumin-bilirubin complex.
Topics: Alkylation; Animals; Aspirin; Bilirubin; Binding Sites; Binding, Competitive; Carrier Proteins; Cattle; Dimethyl Sulfoxide; Fatty Acids; Female; Fluorescence; Humans; Hydrogen-Ion Concentration; Hyperbilirubinemia, Hereditary; Infant, Newborn; Oleic Acids; Pregnancy; Protein Binding; Salicylates; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry; Sulfisoxazole | 1973 |
Possible genetic links between cystic fibrosis of the pancreas and aspirin sensitive asthma.
Topics: Amino Acids; Animals; Aspirin; Asthma; Binding Sites; Cystic Fibrosis; Drug Hypersensitivity; Heterozygote; Humans; Immunoglobulins; Karyotyping; Nasal Polyps; Protein Binding; Rabbits; Salicylates; Saliva; Serum Globulins; Sweat; Time Factors; Tryptophan | 1973 |
Whole-body autoradiography of late pregnant mice after intravenous injection of 14C-labelled salicylic acid and acetylsalicylic acid.
Topics: Animals; Aspirin; Autoradiography; Carbon Isotopes; Connective Tissue; Female; Fetus; Hydrolysis; Injections, Intravenous; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Pregnancy; Pregnancy, Animal; Protein Binding; Salicylates; Time Factors; Vitreous Body | 1973 |
Oral absorption of commercial buffered aspirin tablets.
Topics: Administration, Oral; Adult; Aspirin; Buffers; Humans; Salicylates; Tablets | 1973 |
Tinnitus as an indication of therapeutic serum salicylate levels.
Topics: Age Factors; Aged; Arthritis, Rheumatoid; Aspirin; Audiometry; Drug Tolerance; Humans; Indomethacin; Middle Aged; Salicylates; Spectrophotometry; Time Factors; Tinnitus | 1973 |
Interactions of aspirin, indomethacin and other drugs in adjuvant-induced arthritis in the rat.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Body Weight; Chlorpromazine; Cyclophosphamide; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Hydrocortisone; Indomethacin; Male; Mycobacterium; Phenytoin; Prednisolone; Rats; Salicylates; Spironolactone; Time Factors | 1973 |
Transport of salicylates from blood to joint fluid.
Topics: Administration, Oral; Adult; Arthritis; Arthritis, Rheumatoid; Aspirin; Bursitis; Humans; Middle Aged; Osteoarthritis; Psoriasis; Salicylates; Synovial Fluid; Synovitis; Time Factors | 1973 |
Aspirin dosages for the cat.
Topics: Administration, Oral; Alanine Transaminase; Animals; Aspirin; Bilirubin; Blood Urea Nitrogen; Cats; Salicylates | 1973 |
The recrystallization and dissolution of acetylsalicylic acid.
Topics: 1-Propanol; Acetone; Aspirin; Chemical Precipitation; Crystallization; Ethanol; Glycerol; Hydrochloric Acid; Methanol; Salicylates; Solubility; Solvents; Spectrometry, Fluorescence; Time Factors; X-Ray Diffraction | 1973 |
Pyloric stenosis: hold-up of enteric coated aspirin tablets.
Topics: Aged; Arthritis, Rheumatoid; Aspirin; Drug Compounding; Female; Foreign Bodies; Humans; Hydrogen-Ion Concentration; Jejunum; Pyloric Stenosis; Salicylates; Stomach; Tablets, Enteric-Coated; Vagotomy | 1973 |
[Gold therapy and agranulocytosis].
Topics: Adult; Agranulocytosis; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzyl Compounds; Collagen; Dimethylamines; Erythrocytes; Female; Gold; Half-Life; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Indazoles; Indomethacin; Male; Mice; Middle Aged; Phenylbutazone; Prednisone; Salicylates; Synovial Fluid; Thiosulfates; Triaziquone | 1973 |
Protein binding of drugs in plasma from patients with acute renal failure.
Topics: Acute Kidney Injury; Aged; Aspirin; Blood Proteins; Female; Humans; In Vitro Techniques; Male; Middle Aged; Phenylbutazone; Phenytoin; Protein Binding; Salicylates; Serum Albumin; Sulfadiazine; Thiopental | 1973 |
Editorial: Aspirin-induced hepatic injury.
Topics: Animals; Aspirin; Chemical and Drug Induced Liver Injury; Child; Drug Hypersensitivity; Humans; Liver; Rabbits; Salicylates | 1974 |
Kinetics of salicylate elimination by newborn infants of mothers who ingested aspirin before delivery.
Topics: Aspirin; Carbon Tetrachloride; Chromatography, Gas; Female; Gentisates; Glucuronates; Glycine; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Methods; Pregnancy; Salicylates; Specimen Handling; Time Factors; Urinary Catheterization | 1974 |
Benorylate in management of Still's disease.
Topics: Acetaminophen; Acetanilides; Adolescent; Arthritis, Juvenile; Aspirin; Child; Child, Preschool; Female; Humans; Infant; Liver Function Tests; Male; Salicylates; Time Factors | 1974 |
Aspirin and the kidney. New Zealand Rheumatism Association Study.
Topics: Acetaminophen; Adult; Arthritis, Rheumatoid; Aspirin; Caffeine; Codeine; Drug Synergism; Female; Humans; Kidney Diseases; Male; Middle Aged; New Zealand; Osteoarthritis; Phenacetin; Phenylbutazone; Salicylates; Urinary Tract Infections | 1974 |
The effects of some salicylate analogues on human blood platelets. 1. Structure activity relationships and the inhibition of platelet aggregation.
Topics: Adult; Aminosalicylic Acids; Aspirin; Benzoates; Blood Platelets; Collagen; Densitometry; Female; Humans; Kinetics; Male; Platelet Adhesiveness; Salicylates; Structure-Activity Relationship | 1974 |
The effects of some salicylate analogues on human blood platelets. 2. The role of platelet acetylation in the inhibition of platelet aggregation.
Topics: Acetates; Acetylation; Aspirin; Benzoates; Biological Transport; Blood Platelets; Carbon Radioisotopes; Collagen; Humans; Kinetics; Oligomycins; Platelet Adhesiveness; Propionates; Salicylates; Structure-Activity Relationship; Time Factors; Ultrasonics | 1974 |
Effect of selected surfactants, above and below the CMC, on aspirin solubility.
Topics: Analysis of Variance; Aspirin; Benzalkonium Compounds; Cetylpyridinium; Chemical Phenomena; Chemistry; Fatty Acids; Hexoses; Hydrolysis; Kinetics; Oleic Acids; Polyethylene Glycols; Salicylates; Sodium Dodecyl Sulfate; Solubility; Spectrophotometry; Succinates; Surface-Active Agents | 1974 |
Simple modified colorimetric method for total salicylate assay in urine after salicylate administration.
Topics: Administration, Oral; Adult; Aspirin; Colorimetry; Humans; Indicators and Reagents; Methods; Salicylates; Time Factors | 1974 |
[Colorimetric determination of acetylsalicylic acid diethylaminoethyl ester hydrochloride (Edan)].
Topics: Aspirin; Chromatography, Thin Layer; Colorimetry; Diethylamines; Hydrolysis; Indicators and Reagents; Salicylates | 1974 |
The clinical significance of hypouricemia.
Topics: Allopurinol; Amino Acids; Aspirin; Autoanalysis; Creatinine; Glycosuria; Humans; Kidney Diseases; Neoplasms; Phosphates; Porphobilinogen; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Salicylates; Uric Acid; Xanthine Oxidase | 1974 |
Rectal absorption from aspirin suppositories in children and adults.
Topics: Administration, Oral; Adolescent; Adult; Aspirin; Biopharmaceutics; Child; Child, Preschool; Defecation; Female; Humans; Male; Rectum; Salicylates; Suppositories; Time Factors | 1974 |
Proceedings: The effects of aspirin, carbenoxolone, and gefarnate on the gastric mucosal potential difference in man.
Topics: Aspirin; Electric Conductivity; Fatty Acids, Unsaturated; Gastric Acidity Determination; Gastric Mucosa; Gastritis; Glycyrrhiza; Humans; Hydrogen-Ion Concentration; Plants, Medicinal; Salicylates; Sesquiterpenes; Stomach Ulcer; Succinates; Triterpenes | 1974 |
Salicylate inhibition of in vitro plasminogen activation by saline extracts of rat tissues.
Topics: Animals; Aspirin; Brain; Enzyme Activation; Fibrin; Kidney; Liver; Lung; Male; Muscles; Myocardium; Plasminogen; Rats; Salicylates; Sodium Chloride; Time Factors; Tissue Extracts | 1974 |
The influence of age on the activity of acetylsalicylic acid-esterase and protein-salicylate binding.
Topics: Adolescent; Adult; Age Factors; Aspirin; Blood Proteins; Child; Esterases; Female; Fluorometry; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Protein Binding; Salicylates | 1974 |
Physiologic surface-active agents and drug absorption. IV. Effect of pre-micellar concentrations of surfactant on dissolution rate.
Topics: Aspirin; Bile Acids and Salts; Buffers; Capsules; Ethers; Gastric Juice; Gastric Mucins; Hydrogen-Ion Concentration; Lysophosphatidylcholines; Pepsin A; Powders; Salicylamides; Salicylates; Solubility; Spectrophotometry; Surface Tension; Surface-Active Agents; Tablets | 1969 |
Plasma salicylate concentrations following chronic administration of aspirin as conventional and sustained-release tablets.
Topics: Aspirin; Delayed-Action Preparations; Humans; Male; Salicylates; Tablets | 1969 |
Inactivation of human serum plasminogen antiactivator by synthetic fibrinolysis inducers.
Topics: Animals; Antifibrinolytic Agents; Antigens; Aspirin; Benzoates; Blood Coagulation Factors; Chemical Precipitation; Chromatography; Dextrans; Fibrinolysis; Flufenamic Acid; Humans; Immune Sera; Immunodiffusion; Lipoproteins; Macroglobulins; Plasminogen; Quaternary Ammonium Compounds; Rabbits; Salicylates | 1969 |
[Cytostatic antiphlogistics. II. Antimicrobial activity range and comparison in the Oedipus test].
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Aspirin; Azaguanine; Azathioprine; Bacteria; Benzimidazoles; Depression, Chemical; Edema; Enterococcus faecalis; Flufenamic Acid; Fungi; Indomethacin; Lactobacillus; Mefenamic Acid; Mercaptopurine; Oxyphenbutazone; Phenylbutazone; Purines; Pyrimethamine; Rats; Riboflavin; Salicylates; Staphylococcus; Tetracycline; Thioguanine | 1970 |
Degradation of acetylsalicylic acid by a strain of Acinetobacter lwoffii.
Topics: Acetates; Adipates; Alcaligenes; Aspirin; Carbon Dioxide; Catechols; Cell-Free System; Chromatography, Gas; Coenzymes; Culture Media; Decarboxylation; Edetic Acid; Hydrolysis; Infrared Rays; Lactones; Manganese; Manometry; Oxygen Consumption; Salicylates; Spectrophotometry; Succinates | 1971 |
Absorption kinetics of aspirin in man following oral administration of an aqueous solution.
Topics: Administration, Oral; Animals; Aspirin; Computers, Analog; Digestive System; Half-Life; Humans; Hydrolysis; In Vitro Techniques; Injections, Intravenous; Intestinal Absorption; Kinetics; Male; Models, Biological; Rabbits; Salicylates; Time Factors | 1972 |
Studies on the polymorphism of acetylsalicylic acid.
Topics: Aspirin; Crystallization; Infrared Rays; Salicylates; Solutions; Spectrum Analysis; Temperature; Ultraviolet Rays | 1972 |
Effect of intravenous infusion of acetylsalicyclic acid on renal function.
Topics: Adult; Aminohippuric Acids; Aspirin; Creatine; Glomerular Filtration Rate; Humans; Injections, Intravenous; Inulin; Kidney; Kidney Function Tests; Middle Aged; Salicylates | 1972 |
The inhibition of goldthioglucose and bipiperidyl mustard-induced hypothalamic lesions by anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Atropine; Chlorpromazine; Glucose; Gold; Heparin; Hydrocortisone; Indomethacin; Male; Mice; Mustard Compounds; Pyrogallol; Salicylates; Sodium Chloride | 1972 |
Salicylate accumulation kinetics in man.
Topics: Adult; Aspirin; Biotransformation; Half-Life; Humans; Hydrolysis; Injections, Intravenous; Kinetics; Mathematics; Salicylates; Sodium Salicylate; Time Factors | 1972 |
Application of salivary salicylate data to biopharmaceutical studies of salicylates.
Topics: Aspirin; Biopharmaceutics; Humans; Male; Mathematics; Salicylates; Saliva; Spectrometry, Fluorescence; Tablets, Enteric-Coated; Time Factors | 1972 |
Simnultaneous metabolism of aspirin and acetaminophen in man.
Topics: Acetaminophen; Aspirin; Drug Interactions; Fluorescence; Humans; Kinetics; Salicylates | 1972 |
Aspirin intolerance in asthma. Detection by oral challenge.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Glucocorticoids; Humans; Male; Polyps; Respiratory Function Tests; Salicylates; Sinusitis; Skin Tests | 1972 |
Enhancement of the antihemostatic effect of acetylsalicylic acid by ring iodination.
Topics: Animals; Anticoagulants; Aspirin; Blood Coagulation Tests; Depression, Chemical; Dose-Response Relationship, Drug; Female; Hemostasis; Injections, Intraperitoneal; Iodine; Mice; Mice, Inbred Strains; Platelet Adhesiveness; Salicylates; Structure-Activity Relationship | 1972 |
The experimental modification of lysosomal dysfunction by anti-inflammatory drugs acting in vitro.
Topics: Acetaminophen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Cells, Cultured; Histamine; Humans; In Vitro Techniques; Inflammation; Lysosomes; Membranes; Permeability; Salicylates; Skin Diseases; Synovial Membrane | 1972 |
[Dialysis of drugs and poisons. 2].
Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine | 1972 |
Dissolution rates and serum salicylate levels with acetylsalicylic acid (B.P.) and acetylsalicylic acid in "fine-particle" form.
Topics: Adult; Aspirin; Dosage Forms; Female; Humans; Intestinal Absorption; Male; Salicylates | 1971 |
[Effect of bile and bile components on the absorption of salicylic acid derivatives in rat gastrointestinal tract].
Topics: Animals; Aspirin; Bile Acids and Salts; Gastric Mucosa; Intestinal Absorption; Rats; Salicylates | 1971 |
[Pharmacological studies of troponoids. I. Hypothermic, analgesic and anti-inflammatory actions of troponoids].
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Antipyrine; Aspirin; Body Temperature; Capillary Permeability; Chlorpromazine; Cycloheptanes; Erythema; Hexobarbital; Ketones; Male; Mice; Motor Activity; Pentylenetetrazole; Rats; Salicylates; Sleep; Strychnine | 1971 |
Aspirin poisoning.
Topics: Acidosis; Acute Disease; Aspirin; Humans; Poisoning; Prognosis; Salicylates | 1971 |
Hydrolysis of salicylsalicylic acid in human blood and plasma: a comparison with acetylsalicylic acid.
Topics: Aspirin; Half-Life; Humans; In Vitro Techniques; Plasma; Salicylates | 1971 |
Salicylate-induced foetal damage during late pregnancy in mice: a comparison between sodium salicylate, acetylsalicylic acid and salicylsalicylic acid.
Topics: Animals; Aspirin; Female; Fetal Death; Gestational Age; Hemorrhage; Liver Glycogen; Mice; Pregnancy; Salicylates | 1971 |
[X-ray diffraction applied to the study of the structure of pharmacologically active substances].
Topics: Aspirin; Barbiturates; Chemistry, Pharmaceutical; Indoleacetic Acids; Norepinephrine; Pharmaceutical Preparations; Salicylates; Sulfanilamides; Sulfonamides; X-Ray Diffraction | 1971 |
Gas-liquid chromatography in pharmacology and toxicology. Pharmacokinetic analysis limited by the sensitivity of the analytical technique.
Topics: Animals; Aspirin; Barbiturates; Brompheniramine; Chlorpheniramine; Chromatography, Gas; Ethyl Biscoumacetate; Evaluation Studies as Topic; Half-Life; Humans; Kidney; Kinetics; Mass Spectrometry; Mathematics; Methods; Models, Biological; Pharmaceutical Preparations; Phenethylamines; Radioisotopes; Rats; Salicylates; Saliva | 1971 |
Use of general partial fraction theorem for obtaining inverse laplace transforms in pharmacokinetic analysis.
Topics: Absorption; Aspirin; Injections, Intravenous; Kinetics; Models, Biological; Pharmacology; Salicylates | 1971 |
Acetylsalicylic acid: inhibition of platelet aggregation in the rabbit.
Topics: Animals; Aspirin; Carbon Isotopes; Platelet Adhesiveness; Rabbits; Salicylates; Time Factors; Tritium | 1971 |
[Rapid method for the determination of salicylates in blood].
Topics: Aspirin; Humans; Indicators and Reagents; Methods; Salicylates; Sodium Salicylate; Time Factors | 1971 |
Inhibitory effects of some anti-inflammatory and other analgesics and nitrofurans on the induction of -galactosidase synthesis in Klebsiella aerogenes.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Aspirin; Enzyme Induction; Furazolidone; Galactosidases; Klebsiella; Morphine; Nalorphine; Niridazole; Nitrofurans; Nitrofurantoin; Nitrofurazone; Phenacetin; Salicylamides; Salicylates | 1971 |
Effects of non-steroid antirheumatic agents on microsomal drug-metabolizing enzymes of rat liver.
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Ascorbic Acid; Aspirin; Benzyl Compounds; Enzyme Induction; Flufenamic Acid; Hexobarbital; In Vitro Techniques; Indazoles; Indomethacin; Liver; Male; Mefenamic Acid; Methylamines; Methyltransferases; Microsomes, Liver; Organ Size; Oxidoreductases; Phenobarbital; Pyrazoles; Rats; Salicylamides; Salicylates; Sleep; Sodium Salicylate | 1971 |
[On the treatment of rheumatic disease].
Topics: Aspirin; Child; Child, Preschool; Humans; Penicillins; Prednisone; Rheumatic Fever; Rheumatic Heart Disease; Salicylates | 1968 |
Sodium bicarbonate therapy for salicylate poisoning.
Topics: Aspirin; Bicarbonates; Child, Preschool; Female; Humans; Male; Poisoning; Salicylates | 1969 |
[Be suspicious of aspirin (salicylic acid poisoning)].
Topics: Aspirin; Salicylates | 1970 |
An automated colorimetric method for determination of free salicylic acid in aspirin-containing products.
Topics: Analgesics; Aspirin; Autoanalysis; Azepines; Caffeine; Codeine; Colorimetry; Meperidine; Meprobamate; Methods; Phenacetin; Salicylates | 1968 |
Research strikes forth in new directions. 3.
Topics: Analgesics; Anti-Inflammatory Agents; Arthritis; Aspirin; Cortisone; Drug Industry; Glucocorticoids; Gold; Humans; Prednisolone; Prednisone; Research; Salicylates | 1969 |
Salicylate poisoning in children.
Topics: Aspirin; Child; Humans; Salicylates | 1969 |
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.
Topics: Animals; Arachidonic Acids; Aspirin; Biological Assay; Chromatography, Thin Layer; Colon; Guinea Pigs; Indomethacin; Lung; Prostaglandins; Rats; Salicylates; Stomach | 1971 |
Heidenhain pouch bleeding due to oral salicylates.
Topics: Animals; Aspirin; Chromium Isotopes; Dogs; Gastric Mucosa; Gastrointestinal Hemorrhage; Salicylates | 1966 |
Effect of inhibitors of plasmin, kallikrein and kinin on mortality from scalding in mice.
Topics: Aminocaproates; Animals; Aprotinin; Aspirin; Burns; Enzyme Therapy; Male; Mice; Phenylbutazone; Salicylates; Shock | 1966 |
[Gastrointestinal bleeding and salicylates. A comparative study between acetylsalicylic acid and salicylsalicylic acid].
Topics: Adult; Aged; Aspirin; Feces; Female; Gastrointestinal Hemorrhage; Humans; Male; Melena; Middle Aged; Salicylates | 1968 |
Platelet dysfunction--differentiation of a newly recognized primary type from that produced by aspirin.
Topics: Adenine Nucleotides; Adult; Aspirin; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Blood Transfusion; Centrifugation; Collagen; Diagnosis, Differential; Epinephrine; Female; Glass; Hemorrhagic Disorders; Humans; Male; Middle Aged; Salicylates; Serotonin; Thrombin; Trypsin; von Willebrand Diseases | 1969 |
Failure of intravenous aspirin to increase gastrointestinal blood loss.
Topics: Adult; Aspirin; Chromium Isotopes; Erythrocytes; Feces; Gastric Juice; Gastrointestinal Hemorrhage; Humans; Injections, Intravenous; Male; Occult Blood; Salicylates; Saliva | 1969 |
[Medical therapeutic management of chronic inflammatory rheumatism].
Topics: Adrenal Cortex Hormones; Antimalarials; Antineoplastic Agents; Arthritis, Rheumatoid; Aspirin; Chronic Disease; Gold Colloid, Radioactive; Humans; Immunosuppressive Agents; Indomethacin; Pyrazoles; Rheumatic Diseases; Salicylates; Ultrasonic Therapy | 1969 |
Gastroscopic findings and fecal blood loss following aspirin administration.
Topics: ABO Blood-Group System; Adult; Aspirin; Blood Group Antigens; Chromium Isotopes; Erythrocytes; Feces; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Occult Blood; Prothrombin; Salicylates | 1969 |
Aspirin and alternatives.
Topics: Adult; Analgesics; Anti-Inflammatory Agents; Aspirin; Fever; Gastrointestinal Hemorrhage; Humans; Intestinal Absorption; Kidney Diseases; Salicylates; Uricosuric Agents | 1970 |
Assessment of drug-induced occult bleeding.
Topics: Adult; Aged; Aspirin; Chromium Isotopes; Erythrocytes; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Occult Blood; Rheumatic Diseases; Salicylates | 1971 |
Effect of aspirin and related compounds on the fine structure of mouse gastric mucosa.
Topics: Acetates; Administration, Oral; Animals; Aspirin; Benzoates; Carboxylic Acids; Epithelium; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Hydrochloric Acid; Male; Mice; Microscopy, Electron; Salicylamides; Salicylates | 1971 |
Assessment of drug-induced gastric bleeding.
Topics: Anti-Inflammatory Agents; Aspirin; Choline; Chromium Isotopes; Erythrocytes; Feces; Gastrointestinal Hemorrhage; Humans; Mass Screening; Outpatient Clinics, Hospital; Salicylates | 1971 |
Effects of streptomycin, kanamycin, quinine, and other drugs on the microphonic potentials of goldfish sacculus.
Topics: Action Potentials; Animals; Aspirin; Azides; Cyanides; Cyprinidae; Depression, Chemical; Dinitrophenols; Ear, Inner; Kanamycin; Procaine; Quinine; Salicylates; Streptomycin; Tetrodotoxin | 1971 |
The kinetics of elimination of salicylic acid and the formation of gentisic acid.
Topics: Aspirin; Chromatography, Thin Layer; Fluorometry; Gentisates; Humans; Kinetics; Methods; Models, Theoretical; Salicylates | 1969 |
Absorption of acetylsalicylic acid b a normal and an atrophic gastic mucosa.
Topics: Absorption; Aspirin; Atrophy; Cobalt Isotopes; Gastric Mucosa; Gastritis; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Methods; Salicylates; Time Factors | 1969 |
Pharmaceutical heterogeneous system. IV. A kinetic approach to the stability screening of solid dosage forms containing aspirin.
Topics: Aspirin; Colorimetry; Dosage Forms; Drug Compounding; Drug Stability; Kinetics; Powders; Salicylates; Solvents; Spectrophotometry; Suspensions; Tablets | 1969 |
The pharmacological properties of ibuprofen, an anti-inflammatory, analgesic and antipyretic agent.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Codeine; Dextropropoxyphene; Erythema; Female; Guinea Pigs; Inflammation; Male; Oxyphenbutazone; Phenylbutazone; Placebos; Propionates; Rats; Salicylates; Sodium | 1969 |
The protein binding of acetylsalicylic acid and salicylic acid.
Topics: Acrylates; Aspirin; Binding Sites; Carbon Isotopes; Chromatography, Gel; Dialysis; Fluorometry; Humans; Methods; Protein Binding; Salicylates; Serum Albumin; Temperature; Time Factors | 1969 |
[Prevention of thrombosis using aspirin? nfluence of acetylsalicylic acid on thrombocyte aggregation in vitro and in vivo].
Topics: Aspirin; Blood Coagulation Tests; Blood Platelets; Dipyridamole; Female; Humans; Middle Aged; Papaverine; Phenylbutazone; Platelet Adhesiveness; Salicylates; Thrombosis | 1969 |
[Determination of the salicylate level in plasma after administration of acetylsalicylic acid as well as a combination of acetylsalicylic acid and ascorbic acid].
Topics: Adult; Ascorbic Acid; Aspirin; Female; Humans; Male; Middle Aged; Salicylates; Solubility; Technology, Pharmaceutical; Time Factors | 1969 |
[Principles and risks of drug treatment of pain].
Topics: Aminopyrine; Analgesics; Antidepressive Agents; Antipyrine; Aspirin; Codeine; Dibenzazepines; Humans; Imipramine; Levallorphan; Levorphanol; Methadone; Morphine; Pain; Phenacetin; Phenylbutazone; Pyrazoles; Salicylamides; Salicylates; Sulfonic Acids | 1969 |
Two-compartment model for a drug and its metabolite: application to acetylsalicylic acid pharmacokinetics.
Topics: Aspirin; Injections, Intravenous; Kinetics; Models, Chemical; Salicylates | 1970 |
Fluorometric determination of salicylic acid in aspirin products including noninterfering, interfering, and buffered substances.
Topics: Acetaminophen; Aspirin; Buffers; Caffeine; Fluorometry; Methods; Salicylates; Tablets | 1970 |
Platelet function studies in human beings receiving 300 mg. of aspirin per day.
Topics: Adult; Aspirin; Blood Platelets; Cell Aggregation; Collagen; Humans; Middle Aged; Platelet Adhesiveness; Salicylates; Thrombosis; Time Factors | 1970 |
[Sideremic curves after administration of iron in subjects treated with salicylate].
Topics: Adolescent; Adult; Aspirin; Female; Humans; Iron; Male; Middle Aged; Salicylates | 1970 |
[Current analgesic anti-inflammatory drugs].
Topics: Analgesics; Aniline Compounds; Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Gastrointestinal Diseases; Humans; Indomethacin; Inflammation; Lysosomes; ortho-Aminobenzoates; Peptic Ulcer; Pyrazoles; Salicylates | 1970 |
Fluorescence of acetylsalicylic acid in solution and its measurement in presence of salicylic acid.
Topics: Aspirin; Fluorescence; Fluorometry; Luminescent Measurements; Salicylates | 1970 |
Clinical evaluation of choline salicylate ear-drops.
Topics: Adolescent; Adult; Aspirin; Choline; Ear Diseases; Female; Humans; Male; Otitis Media; Pain; Salicylates | 1970 |
Salicylates and malformations.
Topics: Abnormalities, Drug-Induced; Aspirin; Central Nervous System; Clubfoot; Digestive System Abnormalities; Female; Gestational Age; Humans; Pregnancy; Salicylates | 1970 |
Fitting a double-exponential curve to observed salicylate concentrations in blood.
Topics: Aspirin; Kinetics; Mathematics; Methods; Models, Biological; Salicylates; Tetracycline | 1970 |
In vitro evaluation of physiological availability of aspirin tablets.
Topics: Aspirin; In Vitro Techniques; Intestinal Absorption; Salicylates; Solubility; Time Factors | 1970 |
[Correlation between behavior of taurine or glycine and its accelerative effect on absorption of salicylic acid derivatives in gastrointestinal tract of rat].
Topics: Animals; Aspirin; Digestive System; Gastric Mucosa; Glycine; Intestinal Absorption; Intestine, Small; Rats; Salicylates; Taurine | 1970 |
[In vitro study of "availability of drugs. I. Resorption from the gastrointestinal tract].
Topics: Acetanilides; Acids; Alkaloids; Amino Alcohols; Aminopyrine; Analgesics; Aniline Compounds; Antipyrine; Aspirin; Barbiturates; Benzoates; Caprylates; Diffusion; Ephedrine; Gastric Juice; Indicators and Reagents; Intestinal Absorption; Models, Biological; Permeability; Phenols; Quinine; Salicylates; Sulfamerazine; Sulfamethazine; Sulfamethoxypyridazine; Sulfathiazoles; Sulfisomidine; Sulfonamides; Tetraethylammonium Compounds; Theophylline | 1970 |
Drug absorption from the rectum. 3. Asprin and some aspirin derivatives.
Topics: Aluminum; Animals; Aspirin; Calcium; Dogs; Glycerides; Glycols; Intestinal Absorption; Pharmaceutic Aids; Polyethylenes; Rectum; Salicylates; Suppositories | 1970 |
A comparison of an effect of different anti-inflammatory drugs on human platelets.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Epinephrine; Female; Humans; Indomethacin; Male; Middle Aged; Platelet Adhesiveness; Salicylates | 1970 |
Reye's syndrome and salicylate intoxication.
Topics: Adipose Tissue; Aspirin; Brain Diseases; Chemical and Drug Induced Liver Injury; Fatty Liver; Humans; Infant; Kidney Diseases; Peritoneal Dialysis; Salicylates | 1970 |
Effects of salicylic and acetylsalicylic acid on inorganic phosphates and impulse conduction in mammalian nerve fibres.
Topics: Action Potentials; Animals; Aspirin; Depression, Chemical; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Neural Conduction; Oxidative Phosphorylation; Phosphates; Rabbits; Salicylates; Spectrum Analysis; Vagus Nerve | 1970 |
An automated microfluorometric determination for salicylate in body fluids and tissue extracts.
Topics: Animals; Aspirin; Autoanalysis; Brain Chemistry; Chemistry, Clinical; Chromatography, Gel; Dogs; Fluorometry; Humans; Kidney; Liver; Lung; Methods; Mice; Muscles; Myocardium; Rats; Salicylamides; Salicylates; Skin | 1970 |
[Stabilizing effect of anti-inflammatory drugs on erythrocyte membrane. II. On UV-induced canine erythrocyte hemolysisand lipid peroxidation, on UV-induced peroxide formation in extracted lipid, and on irradiated lipid-induced hemolysis].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Betamethasone; Capillary Permeability; Chloroquine; Dogs; Erythrocytes; Female; Flufenamic Acid; Guinea Pigs; Hemolysis; Lipid Metabolism; Lipids; Mefenamic Acid; Oxyphenbutazone; Peroxides; Phenylbutazone; Prednisolone; Radiation Effects; Salicylates; Ultraviolet Rays | 1970 |
[Stabilizing effect of anti-inflammatory drugs on erythrocyte membrane. I. On hemolysis and lipid peroxidation induced by H202 in canine erythrocyte].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Betamethasone; Cell Membrane; Chloroquine; Dogs; Erythrocytes; Flufenamic Acid; Hemolysis; Humans; In Vitro Techniques; Lipid Metabolism; Mefenamic Acid; Oxyphenbutazone; Peroxides; Phenylbutazone; Prednisolone; Salicylates | 1970 |
Mode of stabilizing action of non-steroid anti-inflammatory drugs on erythrocyte membrane.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Blood Coagulation; Cell Membrane; Dogs; Erythrocytes; Flufenamic Acid; Hemolysis; Hot Temperature; Hydrogen-Ion Concentration; Indomethacin; Lysophosphatidylcholines; Nitrobenzenes; ortho-Aminobenzoates; Oxyphenbutazone; Phenylbutazone; Phospholipases; Protein Denaturation; Pyrazoles; Salicylates; Saponins; Serum Albumin, Bovine; Sulfates; Surface-Active Agents | 1970 |
Pharmacological properties of some antirheumatic salicylates.
Topics: Animals; Aspirin; Edema; Female; Gastric Mucosa; Guinea Pigs; Rats; Salicylates; Sulfates; Sulfur Isotopes | 1970 |
Fluorometric determination of salicylic acid in buffered aspirin products.
Topics: Aspirin; Fluorometry; Methods; Salicylates; Tablets | 1971 |
Studies on metabolism and identification of the causative agent in aspirin teratogenesis in rats.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Benzoates; Biotransformation; Female; Fetal Death; Fetus; Gestational Age; Pregnancy; Rats; Salicylates | 1971 |
Current evaluation of drugs for treating arthritis.
Topics: Acetaminophen; Adrenal Cortex Hormones; Arthritis; Arthritis, Rheumatoid; Aspirin; Chloroquine; Codeine; Cortisone; Cyclophosphamide; Dextropropoxyphene; Gold; Gout; Humans; Indomethacin; Mefenamic Acid; Pentazocine; Phenylbutazone; Salicylates; Spondylitis, Ankylosing | 1971 |
Aza analogs of 5-(p-fluorophenyl)salicylic acid.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Models, Chemical; Picolinic Acids; Pyridines; Rats; Salicylates | 1971 |
[Treatment of acute poisoning. 3. Pharmacokinetic treatment principals].
Topics: Acute Disease; Amphetamine; Aspirin; Barbiturates; Dialysis; Diuresis; Gastric Lavage; Half-Life; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Poisoning; Salicylates; Vomiting | 1971 |
Antipyretic properties of some metabolic and structural analogues of sodium salicylate.
Topics: Animals; Aspirin; Benzoates; Biological Transport; Blood-Brain Barrier; Body Temperature; Caproates; Cerebral Ventricles; Dinitrophenols; Fever; Rabbits; Salicylamides; Salicylates; Sodium Salicylate | 1971 |
Dialysis of drugs against activated charcoal.
Topics: Adsorption; Amitriptyline; Aspirin; Charcoal; Chlordiazepoxide; Chloroquine; Dextroamphetamine; Dextropropoxyphene; Dialysis; Diazepam; Glutethimide; Meprobamate; Methaqualone; Models, Biological; Pentazocine; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Salicylates; Secobarbital; Time Factors | 1971 |
A study of propoxyphene and salicylate concentrations in human plasma following the administration of propoxyphene napsylate and aspirin.
Topics: Analysis of Variance; Aspirin; Caffeine; Capsules; Chromatography, Gas; Dextropropoxyphene; Humans; Male; Naphthalenes; Phenacetin; Salicylates; Sulfonic Acids; Suspensions; Tablets | 1971 |
Rapid simultaneous determination of salicylic acid and aspirin by GC. I. Analysis of synthetic aspirin-salicylic acid mixtures and of single-component aspirin tablets.
Topics: Aspirin; Chromatography, Gas; Diazomethane; Methods; Pharmacopoeias as Topic; Salicylates; Tablets; Tablets, Enteric-Coated | 1971 |
Serum transaminases during salicylate therapy.
Topics: Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Alkaline Phosphatase; Arthritis, Juvenile; Aspartate Aminotransferases; Aspirin; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Dermatomyositis; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Salicylates | 1971 |
Salicylic acid concentration in plasma and urine of medicated and nonmedicated horses.
Topics: Animals; Aspirin; Horses; Salicylates | 1968 |
The biosynthesis of intestinal mucins. The effect of salicylate on glycoprotein biosynthesis by sheep colonic and human gastric mucosal tissues in vitro.
Topics: Acyltransferases; Animals; Aspirin; Carbon Isotopes; Coenzyme A; Colon; Gastric Mucosa; Glucosamine; Glucose; Hexosamines; Humans; In Vitro Techniques; Intestinal Mucosa; Ligases; Mucins; Neuraminic Acids; Oxygen Consumption; Salicylates; Sheep; Sulfates; Sulfur Isotopes; Threonine; Transaminases | 1968 |
Interactions of xanthine derivatives with bovine serum albumin. 3. Inhibition of binding.
Topics: Acetates; Aspirin; Benzoates; Binding Sites; Caffeine; Chemical Phenomena; Chemistry; Chlorides; Hydrogen-Ion Concentration; Nitrates; Potassium; Protein Binding; Salicylates; Serum Albumin, Bovine; Sodium; Sulfates; Theophylline; Xanthines | 1968 |
Investigation of the use of derivative neutron activation analysis for drug assay.
Topics: Activation Analysis; Aspirin; Bromides; Bromine; Chlorides; Chlorine; Chlorpromazine; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Drug Stability; Fluorometry; Salicylates; Spectrum Analysis | 1968 |
Concept of a volume of distribution and possible errors in evaluation of this parameter.
Topics: Aspirin; Barbiturates; Griseofulvin; Humans; Injections, Intravenous; Kinetics; Male; Mathematics; Models, Theoretical; Pharmaceutical Preparations; Salicylates | 1968 |
Salicylate therapy in rheumatoid arthritis.
Topics: Alkalosis; Antacids; Anti-Inflammatory Agents; Antibody Formation; Arthritis, Rheumatoid; Aspirin; Drug Hypersensitivity; Gastritis; Humans; Salicylates | 1968 |
Carbonate ester prodrugs of salicylic acid. Synthesis, solubility characteristics, in vitro enzymatic hydrolysis rates, and blood levels of total salicylate following oral administration to dogs.
Topics: Animals; Aspirin; Biotransformation; Blood; Carbonates; Dogs; Salicylates; Solubility | 1968 |
Pharmacology of the hexylcarbonate of salicylic acid.
Topics: Animals; Aspirin; Carbonates; Dogs; Gastric Mucosa; Hydrogen-Ion Concentration; Mice; Permeability; Rats; Salicylates | 1968 |
Separation of acetylsalicylic acid and salicylic acid by Sephadex gel filtration.
Topics: Aspirin; Chromatography, Gel; Fluorometry; Gels; Methods; Salicylates | 1968 |
Development of a sustained-release aspirin tablet.
Topics: Adult; Aspirin; Delayed-Action Preparations; Humans; Male; Salicylates; Solubility; Spectrophotometry; Waxes | 1968 |
Inactivation of enzymes by aspirin and salicylate.
Topics: Alcohol Oxidoreductases; Animals; Aspirin; Chemical Phenomena; Chemistry; Glutamate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases; Horses; Liver; Muscles; Salicylates | 1968 |
Effect of combination of pharmaceuticals on gastrointestinal absorption. I. Combination of caffeine with a few absorbable drugs.
Topics: Absorption; Acetates; Animals; Aspirin; Benzoates; Caffeine; Hydrogen-Ion Concentration; Kinetics; Male; Rabbits; Salicylates; Stomach | 1968 |
[Influence of "antirheumatic drugs" on the "in-vitro" behavior of the rheumatoid factor].
Topics: Adrenal Cortex Hormones; Agglutination Tests; Antimalarials; Aspirin; Hemagglutination Inhibition Tests; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Latex Fixation Tests; Prednisone; Pyrazoles; Quinolines; Rheumatoid Factor; Salicylates; Sodium Salicylate; Thiosulfates | 1968 |
Experimental production of congenital cardiovascular malformations in rats by salicylate poisoning.
Topics: Abnormalities, Drug-Induced; Animals; Aorta; Aspirin; Dextrocardia; Female; Fetal Heart; Gestational Age; Maternal-Fetal Exchange; Pregnancy; Rats; Salicylates; Transposition of Great Vessels | 1968 |
[Salicylic metabolites discovered in the plasma of subjects treated with sodium salicylate and acetylsalicylic acid].
Topics: Aspirin; Female; Humans; Male; Salicylates; Sodium Salicylate | 1968 |
[Hypoglycemic properties of salicylates].
Topics: Amino Acids; Animals; Aspirin; Carbohydrate Metabolism; Fats; Humans; Hypoglycemic Agents; Proteins; Rats; Salicylates; Sodium | 1968 |
Significance of salicylic acid sublimation in stability testing of aspirin-containing solids.
Topics: Aspirin; Drug Stability; Methods; Salicylates; Spectrophotometry; Ultraviolet Rays | 1968 |
Pharmaceutical heterogeneous systems. II. Study of hydrolysis of aspirin in combination with fatty acid tablet lubricants.
Topics: Aspirin; Chromatography, Gas; Drug Stability; Palmitic Acids; Pharmaceutic Aids; Powders; Salicylates; Stearic Acids; Tablets | 1968 |
Pharmaceutical heterogeneous systems. 3. Inhibition of stearate lubricant induced degradation of aspirin by the use of certain organic acids.
Topics: Anhydrides; Aspirin; Capsules; Cyclohexanes; Drug Stability; Hydrogen-Ion Concentration; Magnesium; Malates; Maleates; Salicylates; Spectrophotometry; Stearic Acids; Tartrates | 1968 |
Analgesic activity of acetylsalicylic and salicylic acid and its relation to blood concentrations in mice.
Topics: Analgesics; Animals; Aspirin; Mice; Salicylates | 1968 |
[Enteric aspirin tablets and the salicylate concentration in the plasma in the morning].
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Body Weight; Circadian Rhythm; Female; Humans; Intestinal Absorption; Male; Middle Aged; Salicylates; Solubility; Tablets, Enteric-Coated | 1968 |
Transfer of water and drugs by the isolated intestine of the x-irradiated rat.
Topics: Animals; Aspirin; Bicarbonates; Biological Transport; Cobalt Isotopes; Depression, Chemical; Ethionamide; In Vitro Techniques; Intestinal Absorption; Intestines; Male; Mecamylamine; Radiation Effects; Rats; Salicylates; Stimulation, Chemical; Water | 1968 |
Forced diuresis in the treatment of acute salicylate poisoning in adults.
Topics: Acid-Base Equilibrium; Adolescent; Adult; Aged; Aspirin; Diuresis; Female; Humans; Hydrogen-Ion Concentration; Hypokalemia; Male; Middle Aged; Potassium; Salicylates; Sodium | 1969 |
Studies on the mechanism of action of salicylates. IV. Effect of salicylates on oxidative phosphorylation.
Topics: Animals; Aspirin; In Vitro Techniques; Male; Mitochondria, Liver; Oxidative Phosphorylation; Rats; Salicylates | 1969 |
Comparison of methods for the determination of salicylic acid in buffered aspirin tablets.
Topics: Aspirin; Buffers; Chromatography; Citrates; Methods; Salicylates; Spectrophotometry; Ultraviolet Rays | 1969 |
The clinical pharmacology of salicylates.
Topics: Aspirin; Humans; Salicylates | 1969 |
Gastric dialysis as a possible antidotal procedure for removal of absorbed drugs.
Topics: Aminopyrine; Aniline Compounds; Animals; Aspirin; Chlordiazepoxide; Gastric Lavage; Levorphanol; Mecamylamine; Phenobarbital; Poisoning; Quinine; Rats; Renal Dialysis; Salicylates; Sulfadiazine; Sulfanilamides | 1969 |
Effect of mode of administration on drug distribution in a two-compartment open system.
Topics: Anti-Bacterial Agents; Aspirin; Griseofulvin; Injections, Intravenous; Kinetics; Mathematics; Models, Biological; Pharmaceutical Preparations; Salicylates; Time Factors | 1969 |
Effect of acetylsalicylic acid and phenylbutazone on glucose absorption in vitro.
Topics: Animals; Aspirin; Biological Transport, Active; Depression, Chemical; Glucose; In Vitro Techniques; Intestinal Absorption; Male; Phenylbutazone; Rats; Salicylates | 1969 |
The influence of salicylate on platelets and whole blood adenine nucleotides.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Aspirin; Blood Platelets; Humans; In Vitro Techniques; Platelet Adhesiveness; Salicylates; Sodium Salicylate | 1969 |
Inactivation of enzymes by therapeutic concentrations of aspirin and salicylate.
Topics: Aspirin; Glutamate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases; Salicylates | 1969 |
Polyamide layer chromatography of some antipyretics.
Topics: Acetanilides; Amides; Aminopyrine; Analgesics; Antipyrine; Aspirin; Caffeine; Chromatography, Thin Layer; Indomethacin; Oxyphenbutazone; Phenacetin; Salicylates | 1969 |
In vitro binding of salicylates to saliva proteins.
Topics: Adult; Aspirin; Chromatography, Gel; Fluorometry; Humans; In Vitro Techniques; Male; Middle Aged; Protein Binding; Proteins; Salicylamides; Salicylates; Saliva | 1969 |
Is aspirin safe?
Topics: Adolescent; Adult; Aged; Aspirin; Barbiturates; Child; Child, Preschool; England; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Salicylates; Statistics as Topic; Wales | 1969 |
[Remarks on the administration of acylpyrin].
Topics: Aspirin; Child, Preschool; Female; Humans; Male; Poisoning; Salicylates; Seizures | 1969 |
The excretion of lacate dehydrogenase in human urine after he ingestion of aspiin.
Topics: Adsorption; Aspirin; Electrophoresis; Epithelium; Humans; Isoenzymes; Kidney; L-Lactate Dehydrogenase; Male; Salicylates; Ultrasonics; Urine | 1969 |
Renal accumulation of salicylate and phenacetin: possible mechanisms in the nephropathy of analgesic abuse.
Topics: Analgesics; Animals; Aspirin; Dehydration; Dogs; Female; Humans; Hydrogen-Ion Concentration; Kidney; Kidney Concentrating Ability; Kidney Diseases; Kidney Papillary Necrosis; Osmosis; Phenacetin; Salicylates; Substance-Related Disorders; Urea | 1969 |
Salicylate exposure in the perinate.
Topics: Aspirin; Blood Proteins; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Pregnancy; Protein Binding; Salicylates; Serum Albumin; Umbilical Cord | 1969 |
[On the pharmacokinetic behavior of the new acetylsalicylic acid derivative, 4-(acetylamido)phenyl-2-acetoxybenzoate, in animal experiments].
Topics: Animals; Aspirin; Benzoates; Carbon Isotopes; Chromatography, Thin Layer; Esters; Injections, Intravenous; Intestines; Kinetics; Rats; Salicylates; Stomach; Time Factors | 1969 |
Effect of the vagus nerve and salicylate administration on the permeability characteristics of the rat gastric mucosal barrier.
Topics: Animals; Aspirin; Atropine; Bethanechol Compounds; Carbon Isotopes; Cell Membrane Permeability; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Gastrins; Histamine; Hydrochloric Acid; Hydrogen-Ion Concentration; Male; Peptides; Rats; Salicylates; Vagotomy; Vagus Nerve | 1969 |
Aspirin and salicylic acid, et al.
Topics: Aspirin; Drug Tolerance; Hemorrhage; Humans; Salicylates | 1969 |
Studies of analgesic and anticonvulsant activity in mice by high-frequency electrical stimulation.
Topics: Age Factors; Analgesics; Animals; Anticonvulsants; Aspirin; Body Weight; Electric Stimulation; Electrodes; Hindlimb; Male; Methods; Mice; Pain; Pentazocine; Phenobarbital; Salicylates; Tail; Time Factors; Urea | 1969 |
The application of ultraviolet reflectance spectroscopy to thin-layer chromatography.
Topics: Aspirin; Chromatography, Thin Layer; Salicylates; Spectrophotometry; Ultraviolet Rays | 1965 |
Blood levels of aspirin following the ingestion of commercial aspirin-containing tablets by humans.
Topics: Aspirin; Blood; Humans; In Vitro Techniques; Salicylates | 1965 |
[Drug quality supervision by spot tests. 3. Data to the determination of acetylsalicylic acid and calcium acetyl salicylate].
Topics: Aspirin; Calcium; Chemistry, Pharmaceutical; In Vitro Techniques; Salicylates | 1965 |
Pharmacokinetics of salicylate elimination in man.
Topics: Adult; Aspirin; Humans; Kinetics; Male; Salicylates; Urine | 1965 |
A kinetic study of the elimination of 3-methylsalicylic acid and its acetyl derivative in man.
Topics: Aspirin; Blood; Humans; Salicylates; Urine | 1965 |
[Clinical tolerance and biological study of a compound of acetylsalicylic acid: TH 2152].
Topics: Aspirin; Drug Tolerance; Humans; Pain; Salicylates | 1963 |
[Study of salicylemia after absorption of coated acetylsalicylic acid; comparison with the results obtained with classical preparations].
Topics: Aspirin; Humans; Intestinal Absorption; Phthalic Acids; Salicylates; Tablets, Enteric-Coated | 1965 |
Some aspects of salicylate distribution and metabolism in man.
Topics: Adult; Aspirin; Blood Proteins; Humans; Intestinal Absorption; Salicylates; Urine | 1965 |
In vivo drug release rate from hard gelatin capsules.
Topics: Aspirin; Blood; Capsules; Gelatin; Humans; Salicylates; Tablets | 1965 |
Assay for free salicylic acid in individual capsules and tablets of aspirin or aspirin containing medicinals.
Topics: Absorption; Aspirin; Caffeine; Capsules; Chemistry, Pharmaceutical; Drug Stability; Phenacetin; Salicylates; Spectrophotometry; Tablets | 1965 |
[Resorption and excretion of salicylic acid after intramuscular injection of aluminum acetylsalicylic acid].
Topics: Aluminum; Animals; Aspirin; Blood; In Vitro Techniques; Injections, Intramuscular; Rabbits; Rats; Salicylates; Suspensions; Urine | 1965 |
Salicylates and urinary excretion of histamine.
Topics: Adult; Aspirin; Biological Assay; Female; Histamine; Humans; Magnesium Oxide; Male; Middle Aged; Salicylates | 1965 |
Infants, toddlers, and aspirin.
Topics: Accidents; Aspirin; Child; Child, Preschool; England; Epidemiologic Methods; Humans; Iatrogenic Disease; Infant; Mortality; Salicylates; Scotland; Wales | 1966 |
Salicylic acid in aspirin mixture, B.N.F.
Topics: Aspirin; Chemistry, Pharmaceutical; Child; Formularies as Topic; Humans; Salicylates; United Kingdom | 1966 |
Analysis of selected pharmaceuticals by quantitative thin-layer chromatography.
Topics: Amphetamine; Aspirin; Barbiturates; Caffeine; Chromatography, Thin Layer; Ephedrine; Methamphetamine; Phenacetin; Salicylates; Theophylline | 1966 |
Determination of free salicylic acid in aspirin and aspirin products.
Topics: Aspirin; Chromatography; Salicylates | 1966 |
Peritoneal dialysis for severe salicylism: an evaluation of indications and results.
Topics: Adult; Aspirin; Child, Preschool; Female; Humans; Infant; Male; Peritoneal Dialysis; Salicylates | 1966 |
Studies on salicylates and complement in diabetes.
Topics: Adolescent; Adult; Aspirin; Complement System Proteins; Diabetes Mellitus; Diabetic Retinopathy; Female; Humans; Male; Middle Aged; Salicylates | 1966 |
The effects of salicylates on growth in immature rats.
Topics: Animals; Animals, Newborn; Aspirin; Body Weight; Growth; Humans; Infant, Newborn; Rats; Salicylates; Tibia | 1966 |
[Treatment of poisoning by aspirin and salicylates].
Topics: Aspirin; Humans; Salicylates | 1966 |
Serum hexosamine levels in normal subjects.
Topics: Adolescent; Adult; Aspirin; Erythromycin; Heparin; Hexosamines; Humans; Kanamycin; Salicylates | 1966 |
Fluorometric determination of acetylsalicylic acid and salicylic acid in blood.
Topics: Aspirin; Blood Specimen Collection; Chromatography, Paper; Female; Fluorometry; Humans; Male; Salicylates | 1966 |
Direct spectrophotometric determination of salicylic acid, acetylsalicylic acid, salicylamide, caffeine, and phenacetin in tablets or powders.
Topics: Aspirin; Caffeine; Phenacetin; Powders; Salicylamides; Salicylates; Spectrophotometry; Tablets; Ultraviolet Rays | 1966 |
Experimental production of malformations due to acetyl salicylate and phenyl salicylate in rats.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Female; Pregnancy; Pregnancy, Animal; Rats; Salicylates | 1966 |
The influence of analgesic antipyretic drugs on the responses of guinea-pig lungs to bradykinin.
Topics: Aminopyrine; Analgesics; Animals; Antipyrine; Aspirin; Bradykinin; Bronchi; Central Nervous System; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Perfusion; Phenylbutazone; Salicylates | 1966 |
Gas-liquid chromatography of submicrogram amounts of drugs. II. Analysis of barbiturates and related drugs in biological media.
Topics: Amobarbital; Aspirin; Barbiturates; Bemegride; Caffeine; Chromatography, Gas; Glutethimide; Hexobarbital; Humans; Liver Extracts; Pentobarbital; Salicylates; Secobarbital | 1966 |
Method for the direct measurement of acetylsalicylic acid in human blood.
Topics: Aspirin; Autoanalysis; Glucuronates; Humans; Salicylamides; Salicylates; Uric Acid | 1966 |
[Studies on the splitting of acetylsalicylic acid during tablet preparation].
Topics: Aspirin; Drug Compounding; Drug Stability; Salicylates; Tablets | 1966 |
[Analysis of pharmaceuticals by autoanalyzer. II. Determination of acetylsalicylic acid, salicylic acid and its sodium salt in pharmaceutical preparations].
Topics: Analgesics; Aspirin; Autoanalysis; Salicylates; Sodium Salicylate | 1966 |
[The effect of acetylsalicylic acid and of disalicylic acid on the ventricular muscosa of the guinea pig].
Topics: Animals; Aspirin; Digestive System; Guinea Pigs; Intestinal Mucosa; Salicylates | 1966 |
Salicylate damage to the gastric mucosal barrier.
Topics: Animals; Aspirin; Bethanechol Compounds; Dogs; Gastric Juice; Gastric Mucosa; Histamine; Hydrochloric Acid; Hydrogen; Permeability; Potassium; Salicylates; Serum Albumin; Sodium; Therapeutic Irrigation | 1967 |
Effect of certain nonsteroid antirheumatic drugs on active amino acid transport across the small intestine.
Topics: Animals; Aspirin; Biological Transport, Active; Cricetinae; Dinitrophenols; In Vitro Techniques; Indomethacin; Intestine, Small; Male; Phenylbutazone; Rats; Salicylates; Tryptophan | 1967 |
Acetylsalicylic acid hydrolysis in human blood and plasma. I. Methodology and in vitro studies.
Topics: Acetylcholinesterase; Adult; Aspirin; Erythrocytes; Female; Fluorometry; Humans; In Vitro Techniques; Male; Salicylates | 1967 |
Determination of acetylsalicylic acid and salicylic acid in plasma.
Topics: Aspirin; Carbon Disulfide; Chromatography, Gas; Fluorometry; Humans; Indicators and Reagents; Salicylates | 1967 |
Plasma tricarboxylic acids in salicylate poisoning.
Topics: Acidosis, Respiratory; Adolescent; Aged; Aspirin; Child, Preschool; Citrates; Female; Humans; Lactates; Malates; Male; Salicylates | 1967 |
Differentiating nonaqueous titration of salicylic acid and acetylsalicylic acid combination.
Topics: Aspirin; Dimethylformamide; Potentiometry; Salicylates | 1967 |
Method for the determination of acetylsalicylic acid in the blood.
Topics: Aspirin; Barbiturates; Dextropropoxyphene; Glutethimide; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Indomethacin; Meprobamate; Salicylamides; Salicylates; Spectrophotometry | 1967 |
Accidental poisoning.
Topics: Accidents; Aspirin; Boric Acids; Camphor; Emetics; Humans; Iron; Lead Poisoning; Mercury Poisoning; Petroleum; Poisoning; Salicylates | 1967 |
Interpretation of in vitro dissolution data relative to the gastrointestinal absorption characteristics of drugs in tablets.
Topics: Aspirin; Humans; In Vitro Techniques; Intestinal Absorption; Salicylates; Solubility; Tablets | 1967 |
Generalized pustular psoriasis induced by potassium iodide. A postulated role for dihydrofolic reductase.
Topics: Adolescent; Adrenal Cortex Hormones; Aspirin; Female; Folic Acid; Humans; Iodides; Iron; Male; Middle Aged; Potassium Iodide; Psoriasis; Salicylates; Tetrahydrofolate Dehydrogenase | 1967 |
[Effects of eterylate on "in vitro" Platelet function in human plasma (author's transl)].
Topics: Acetanilides; Anti-Inflammatory Agents; Aspirin; Humans; In Vitro Techniques; Platelet Aggregation; Salicylates | 1980 |
"In vivo" effects of acetylsalicylic acid and two ether derived compounds on primary immune response and lymphoblastic transformation.
Topics: Acetanilides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Female; Hemagglutinins; Immunity; Immunosuppressive Agents; Indomethacin; Lymphocyte Activation; Mice; Salicylates; Thymidine | 1980 |
Poisoning with enteric-coated aspirin.
Topics: Acetaminophen; Aspirin; Humans; Salicylates; Tablets, Enteric-Coated | 1981 |
Salicylate inhibition of antiplatelet effect of aspirin.
Topics: Aspirin; Diflunisal; Humans; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid | 1981 |
Protection against paracetamol-induced glutathione depletion following a paracetamol-acetylsalicylic acid mixture or benorilate in phenobarbital-treated rats.
Topics: Acetaminophen; Animals; Aspirin; Glutathione; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Salicylates | 1981 |
Bioavailability of magnesium salicylate.
Topics: Absorption; Animals; Aspirin; Biological Availability; Dogs; Female; Salicylates; Salicylic Acid | 1981 |
Determination of salicylic acid in acetylsalicylic acid by second derivative u.v.-spectrophotometry.
Topics: Aspirin; Dioxanes; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet | 1982 |
Medicine chest: analgesics. Which is which and what do they do?
Topics: Acetaminophen; Analgesics; Aspirin; Codeine; Humans; Salicylates | 1983 |
[Activity of eterilate, benorylate and acetylsalicylic acid on blood glucose in normal and experimentally diabetic rats].
Topics: Acetanilides; Animals; Aspirin; Blood Glucose; Diabetes Mellitus, Experimental; Female; Hypoglycemia; Rats; Rats, Inbred Strains; Salicylates | 1983 |
Diflunisal and blood acid base status in the rabbit.
Topics: Acid-Base Equilibrium; Animals; Aspirin; Carbon Dioxide; Diflunisal; Female; Hydrogen-Ion Concentration; Male; Rabbits; Salicylates; Time Factors | 1984 |
Absorption of acetylsalicylic acid from enteric-coated tablets in relation to gastric emptying and in-vivo disintegration.
Topics: Aspirin; Gastric Emptying; Humans; Intestinal Absorption; Salicylates; Salicylic Acid; Solubility; Tablets, Enteric-Coated | 1984 |
Effects of diflunisal on fever in the rabbit and the rat.
Topics: Animals; Aspirin; Diflunisal; Dose-Response Relationship, Drug; Female; Fever; Lipopolysaccharides; Male; Rabbits; Rats; Rats, Inbred Strains; Salicylates; Yeasts | 1984 |
Theophylline, dyphylline, caffeine, acetaminophen, salicylate, acetylsalicylate, procainamide, and N-acetylprocainamide determined in serum with a single liquid-chromatographic assay.
Topics: Acecainide; Acetaminophen; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Dyphylline; Humans; Pharmaceutical Preparations; Procainamide; Salicylates; Salicylic Acid; Theophylline | 1982 |
Angiotensin I recovery from plasma incubated with organic reagents.
Topics: Angiotensin I; Angiotensins; Aspirin; Benzoates; Buffers; Humans; Hydrochloric Acid; Maleates; Phenoxyacetates; Phthalic Acids; Protease Inhibitors; Salicylates; Tromethamine | 1981 |
Salicylate-induced occult gastrointestinal blood loss: comparison between different oral and parenteral forms of acetylsalicylates and salicylates.
Topics: Administration, Oral; Aspirin; Dosage Forms; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Injections, Intravenous; Male; Occult Blood; Salicylates | 1984 |
Failure of salicylate to reduce inhibition of human venous prostacyclin in synthesis by conventional dose aspirin.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Epoprostenol; Humans; Kinetics; Prostaglandins; Salicylates; Salicylic Acid; Veins | 1983 |
Selective mitochondrial activity distinguishes aspirin from salicylate and benzoate in yeast cells.
Topics: Aspirin; Benzoates; Benzoic Acid; Mitochondria; Mutation; Oxygen Consumption; Saccharomyces cerevisiae; Salicylates; Salicylic Acid | 1983 |
Effect of salicylates on intestinal secretion in calves given (intestinal loops) Escherichia coli heat-stable enterotoxin.
Topics: Animals; Aspirin; Cattle; Cattle Diseases; Diarrhea; Enterotoxins; Escherichia coli; Intestinal Secretions; Male; Mice; Osmolar Concentration; Salicylates; Salicylic Acid | 1983 |
Salicylate fails to prevent the inhibitory effect of 5,8,11,14-eicosatetraynoic acid on human platelet cyclo-oxygenase and lipoxygenase activities.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Aspirin; Blood Platelets; Fatty Acids, Unsaturated; Humans; Indomethacin; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid | 1983 |
Correlations between changes in indicators of gastric mucosal barrier integrity at time of exposure to "barrier breakers" and extent of hemorrhagic erosions one hour later.
Topics: Animals; Aspirin; Ethanol; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Mannitol; Prognosis; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Stomach Ulcer; Taurocholic Acid | 1984 |
Structural requirements for preventing the aspirin- and the arachidonate-induced inactivation of platelet cyclo-oxygenase: additional evidence for distinct enzymatic sites.
Topics: Animals; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Rabbits; Salicylates; Structure-Activity Relationship; Thromboxane A2 | 1984 |
The effect of acetylsalicylic acid on renal function in the Pekin duck.
Topics: Animals; Arginine Vasopressin; Aspirin; Cyclooxygenase Inhibitors; Diuresis; Ducks; Exocrine Glands; Female; Glomerular Filtration Rate; Kidney; Male; Osmolar Concentration; Renal Circulation; Salicylates; Salicylic Acid | 1984 |
Salicylate:aspirin ratios: relevance to aspirin's antithrombotic action.
Topics: Animals; Aspirin; Binding, Competitive; Cyclooxygenase Inhibitors; Fibrinolytic Agents; Kinetics; Rats; Salicylates; Salicylic Acid | 1984 |
[Divergence between the pharmacologic and clinical effects of inhibitors of prostaglandin synthesis].
Topics: Aspirin; Blood Platelets; Dipyridamole; Drug Interactions; Epoprostenol; Humans; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid; Sulfinpyrazone; Thrombosis; Thromboxanes | 1984 |
Reversible inhibition of thromboxane A2 production by imidazole 2-hydroxybenzoate (ITF 182) in the arachidonic acid injected rat. A comparison with acetylsalicylic acid and indometacin.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Imidazoles; Indomethacin; Injections, Intravenous; Male; Prostaglandins; Rats; Rats, Inbred Strains; Salicylates; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes | 1984 |
Metabolic acidosis induced by carbonic anhydrase inhibitors and salicylates in patients with normal renal function.
Topics: Acetazolamide; Acidosis; Adult; Arthritis; Aspirin; Carbonic Anhydrase Inhibitors; Child; Dichlorphenamide; Drug Interactions; Drug Therapy, Combination; Female; Glaucoma; Humans; Male; Salicylates | 1984 |
The use of drugs in rheumatic diseases.
Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Aurothioglucose; Chloroquine; Colchicine; Gold Sodium Thiomalate; Humans; Hydroxychloroquine; Penicillamine; Prednisone; Rheumatic Diseases; Salicylates | 1984 |
ABC of poisoning. Analgesic poisoning: I--salicylates.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Child; Fluid Therapy; Humans; Ibuprofen; Salicylates; Suction | 1984 |
[Comparison of the pharmacokinetic behavior of Turivital, Acesal and Micristin].
Topics: Adult; Ascorbic Acid; Aspirin; Biological Availability; Caffeine; Carbon Dioxide; Drug Combinations; Drug Interactions; Female; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kinetics; Male; Salicylates; Salicylic Acid | 1984 |
Inhibition of platelet function by a controlled release acetylsalicylic acid formulation--single and chronic dosing studies.
Topics: Adult; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Delayed-Action Preparations; Female; Humans; Male; Malondialdehyde; Platelet Aggregation; Platelet Function Tests; Salicylates; Salicylic Acid; Time Factors | 1984 |
Endosprin, an antipyretic, antiinflammatory and analgesic preparation of lysine salicylate: reassessment of its chemical composition and effects in experimental animals in comparison with aspirin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Combinations; Drug Evaluation, Preclinical; Female; Lysine; Magnetic Resonance Spectroscopy; Male; Mice; Rabbits; Rats; Salicylates | 1984 |
A simple fluorometric method for the determination of salicylic acid in aluminium acetylsalicylate.
Topics: Aspirin; Hydrogen-Ion Concentration; Salicylates; Salicylic Acid; Spectrometry, Fluorescence; Tablets | 1984 |
Methyl salicylate/aspirin (salicylate) equivalence: who do you trust?
Topics: Aspirin; Humans; Molecular Weight; Salicylates; Therapeutic Equivalency | 1984 |
Effects of salicylates and other nonsteroidal anti-inflammatory drugs on articular cartilage.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Atrophy; Cartilage, Articular; Dogs; Extracellular Matrix; Glycosaminoglycans; Indomethacin; Osteoarthritis; Prostaglandin Antagonists; Proteoglycans; Salicylates; Sulfur Radioisotopes; Sulindac; Uronic Acids | 1984 |
Effects of aspirin and salicylic acid on lecithin-cholesterol acyltransferase and cholesterol content in rat serum.
Topics: Animals; Aspirin; Cholesterol; Phosphatidylcholine-Sterol O-Acyltransferase; Rats; Rats, Inbred Strains; Salicylates | 1984 |
Determination of aspirin and salicylic acid in aspirin tablets by second derivative ultraviolet spectrometry.
Topics: Aspirin; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet; Tablets | 1984 |
A clinical evaluation of the antiarthritic agents.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis; Aspirin; Diflunisal; Fenoprofen; Glucocorticoids; Gold; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Naproxen; ortho-Aminobenzoates; Penicillamine; Piroxicam; Prostaglandin Antagonists; Salicylates; Sulindac; Thiazines; Tolmetin | 1984 |
Comparative aspirin absorption kinetics after administration of sodium- and potassium-containing buffered solutions.
Topics: Adult; Aspirin; Buffers; Female; Hippurates; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kinetics; Male; Potassium; Salicylates; Salicylic Acid; Sodium; Solutions | 1984 |
Reye's syndrome: salicylates and mitochondrial functions.
Topics: Animals; Aspirin; Calcium; Humans; Hydroxybutyrates; Mitochondria; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen Consumption; Phosphates; Rats; Reye Syndrome; Salicylates; Salicylic Acid; Structure-Activity Relationship; Succinates; Succinic Acid | 1984 |
Controlled trial of clinical utility of serum salicylate monitoring in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Deafness; Double-Blind Method; Drug Administration Schedule; Evaluation Studies as Topic; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Salicylates; Tinnitus | 1984 |
A pharmacokinetic comparison of choline magnesium trisalicylate and soluble aspirin.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents; Aspirin; Choline; Humans; Kinetics; Male; Middle Aged; Salicylates; Statistics as Topic | 1984 |
Actions and interactions of acetylsalicylic acid, salicylic acid and diflunisal on platelet aggregation.
Topics: Adult; Aspirin; Diflunisal; Drug Interactions; Female; Humans; Male; Middle Aged; Platelet Aggregation; Salicylates; Salicylic Acid | 1984 |
Difficulty in achieving therapeutic serum concentrations of salicylate in Kawasaki disease.
Topics: Aspirin; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Male; Mucocutaneous Lymph Node Syndrome; Prospective Studies; Retrospective Studies; Salicylates; Salicylic Acid | 1984 |
Teratogenicity of aspirin and its metabolite, salicylic acid, in cultured rat embryos.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Embryo, Mammalian; Female; Organ Culture Techniques; Pregnancy; Rats; Rats, Inbred Strains; Salicylates | 1984 |
Rapid and sensitive determination of acetylsalicylic acid and its metabolites using reversed-phase high-performance liquid chromatography.
Topics: Animals; Aspirin; Biotransformation; Chromatography, High Pressure Liquid; Gentisates; Hippurates; Humans; Hydrogen-Ion Concentration; Rats; Salicylates; Salicylic Acid; Species Specificity | 1984 |
Diflunisal-induced maternal anemia as a cause of teratogenicity in rabbits.
Topics: Abnormalities, Drug-Induced; Adenosine Triphosphate; Anemia, Hemolytic; Animals; Antioxidants; Aspirin; Diflunisal; Erythrocytes; Female; Gestational Age; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications, Hematologic; Rabbits; Rats; Rats, Inbred Strains; Salicylates | 1984 |
Aspirin metabolites causing misinterpretation of paracetamol results.
Topics: Acetaminophen; Aspirin; Biotransformation; Chromatography, High Pressure Liquid; Gentisates; Humans; Hydroxybenzoates; Infant; Male; Salicylates; Salicylic Acid | 1984 |
Issues in medication adherence assessment in clinical trials of the National Heart, Lung, and Blood Institute.
Topics: Aspirin; Capsules; Clinical Trials as Topic; Humans; Myocardial Infarction; National Institutes of Health (U.S.); Patient Compliance; Platelet Aggregation; Salicylates; United States | 1984 |
Improved method for the determination of aspirin and its metabolites in biological fluids by high-performance liquid chromatography: applications to human and animal studies.
Topics: Animals; Aspirin; Biological Availability; Chromatography, High Pressure Liquid; Gentisates; Hippurates; Humans; Hydroxybenzoates; Kinetics; Rabbits; Rats; Salicylates; Salicylic Acid; Species Specificity | 1984 |
Salicylate prophylaxis in migraine.
Topics: Adolescent; Adult; Aged; Aspirin; Female; Humans; Male; Middle Aged; Migraine Disorders; Platelet Aggregation; Salicylates; Salicylic Acid; Vascular Headaches | 1984 |
Minimization of salicylic acid formation during preparation of aspirin products for analysis by high-performance liquid chromatography.
Topics: Aspirin; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Salicylates; Salicylic Acid | 1984 |
Esterase-like activity of human serum albumin. IV. Reactions with substituted aspirins and 5-nitrosalicyl esters.
Topics: Aspirin; Esterases; Humans; Nitro Compounds; Salicylates; Serum Albumin; Structure-Activity Relationship | 1984 |
Analysis of tablets containing aspirin, acetaminophen, and ascorbic acid by high-performance liquid chromatography.
Topics: Acetaminophen; Ascorbic Acid; Aspirin; Chromatography, High Pressure Liquid; Drug Stability; Humidity; Hydrogen-Ion Concentration; Salicylates; Salicylic Acid; Tablets; Temperature; Time Factors | 1984 |
Electrostatic effects in acylation of hemoglobin by aspirins.
Topics: Acylation; Aspirin; Chemical Phenomena; Chemistry; Electricity; Hemoglobins; Humans; Salicylates | 1984 |
Simultaneous high-performance liquid chromatography assay of acetylsalicylic acid and salicylic acid in film-coated aspirin tablets.
Topics: Aspirin; Chromatography, High Pressure Liquid; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet; Tablets, Enteric-Coated | 1984 |
Juvenile rheumatoid arthritis.
Topics: Adolescent; Anti-Inflammatory Agents; Arthritis, Juvenile; Aspirin; Child; Child, Preschool; Female; Gold; Humans; Hydroxychloroquine; Joint Prosthesis; Male; Penicillamine; Physical Therapy Modalities; Prednisone; Rheumatoid Factor; Salicylates; Social Support | 1984 |
[Side effects of salicylates].
Topics: Aspirin; Dose-Response Relationship, Drug; Humans; Salicylates; Stomach | 1984 |
Effects of indomethacin, aspirin and related compounds on the transgastric potential difference in cats.
Topics: Animals; Aspirin; Cats; Dinoprostone; Female; Gastric Mucosa; Indomethacin; Infusions, Parenteral; Intubation, Gastrointestinal; Male; Membrane Potentials; Prostaglandins E; Salicylates; Salicylic Acid; Time Factors | 1983 |
Relevance to redesigning aspirin therapeutic regimens.
Topics: Aspirin; Drug Administration Schedule; Humans; Kinetics; Models, Biological; Salicylates; Salicylic Acid | 1983 |
Effects of salicylate and indomethacin on glycosaminoglycan and prostaglandin E2 synthesis in intact canine knee cartilage ex vivo.
Topics: Animals; Aspirin; Cartilage, Articular; Dinoprostone; Dogs; Glycosaminoglycans; Indomethacin; Prostaglandins E; Salicylates; Uronic Acids | 1984 |
Salicylate does not interfere with aspirin in human blood in vivo.
Topics: Adult; Aspirin; Blood Coagulation; Blood Platelets; Humans; Male; Salicylates; Salicylic Acid; Thromboxane B2; Thromboxanes | 1984 |
Rapidly-adapting receptor activity and intratracheal pressure in guinea pigs. II. Action of aspirin and salicylic acid in antagonizing mediators of allergic asthma.
Topics: Animals; Aspirin; Asthma; Bradykinin; Dinoprost; Guinea Pigs; Histamine; Mechanoreceptors; Muscle, Smooth; Pressure; Prostaglandins F; Pulmonary Stretch Receptors; Salicylates; Salicylic Acid; SRS-A; Trachea | 1984 |
Comparison of activated charcoal and gastric lavage in the prevention of aspirin absorption.
Topics: Animals; Aspirin; Charcoal; Dogs; Gastric Lavage; Salicylates; Time Factors | 1984 |
Primary drug therapy: aspirin vs. the nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug Interactions; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Kidney Diseases; Salicylates | 1983 |
Availability of salicylate from salsalate and aspirin.
Topics: Arthritis, Rheumatoid; Aspirin; Biological Availability; Chromatography, High Pressure Liquid; Double-Blind Method; Drug Evaluation; Female; Gentisates; Humans; Hydroxybenzoates; Male; Salicylates; Salicylic Acid | 1983 |
Drug therapy in the management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Azathioprine; Gold; Humans; Penicillamine; Salicylates | 1983 |
Pharmacokinetics of aspirin and salicylate in elderly subjects and in patients with alcoholic liver disease.
Topics: Adult; Aged; Aging; Aspirin; Blood Proteins; Humans; Kinetics; Liver Diseases, Alcoholic; Male; Middle Aged; Models, Biological; Protein Binding; Salicylates; Salicylic Acid | 1983 |
High-performance liquid chromatographic determination of aspirin and its metabolites in plasma and urine.
Topics: Animals; Aspirin; Biotransformation; Chromatography, High Pressure Liquid; Gentisates; Hippurates; Humans; Rats; Salicylates; Salicylic Acid | 1983 |
Effect of water deprivation on aspirin disposition kinetics.
Topics: Animals; Aspirin; Biotransformation; Heparin; Injections, Intravenous; Kinetics; Male; Rats; Salicylates; Salicylic Acid; Water Deprivation | 1983 |
Rapid gas chromatographic determination of serum salicylates after silylation.
Topics: Aspirin; Chromatography, Gas; Humans; Salicylates; Temperature; Time Factors; Trimethylsilyl Compounds | 1983 |
[Comparative pharmacokinetics of salicylic acids administered orally and topically on the skin].
Topics: Administration, Oral; Administration, Topical; Adult; Aspirin; Biological Availability; Humans; Kinetics; Male; Salicylates; Skin Absorption | 1983 |
[Distribution of salicylic acid and hydrolysis of acetylsalicylic acid in the human fetus in early pregnancy].
Topics: Aspirin; Female; Fetus; Humans; Hydrolysis; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, First; Salicylates; Salicylic Acid; Tissue Distribution | 1983 |
Sex differences in the pharmacokinetics of salicylates.
Topics: Adult; Aspirin; Female; Humans; Kinetics; Male; Middle Aged; Salicylates; Sex Factors | 1983 |
Placental transfer of acetylsalicylic acid (ASA) and salicylic acid (SA) in near-term ewes.
Topics: Animals; Aspirin; Female; Fetus; Gestational Age; Kinetics; Maternal-Fetal Exchange; Models, Biological; Pregnancy; Salicylates; Salicylic Acid; Sheep | 1983 |
Effect of high doses of aspirin and salicylate on bleeding time in rats.
Topics: Animals; Aspirin; Bleeding Time; Dose-Response Relationship, Drug; Male; Rats; Salicylates | 1983 |
[Estimation of drug-metabolizing enzyme activities by measuring urinary metabolites of aspirin].
Topics: Animals; Aspirin; Biotransformation; Body Weight; Cytochrome P-450 Enzyme System; Gentisates; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; Organ Size; Phenobarbital; Rats; Salicylates | 1983 |
Studies on the pharmacological bases of fetal toxicity of drugs (IV). Effect of endotoxin and starvation on serum protein binding of salicylic acid in pregnant rats.
Topics: Animals; Aspirin; Blood Proteins; Endotoxins; Fatty Acids, Nonesterified; Female; Fetus; Pregnancy; Protein Binding; Rats; Rats, Inbred Strains; Salicylates; Serum Albumin; Starvation | 1983 |
Effect of salicylates on lymphocyte blastogenesis in vitro: association with other non-steroid anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Diflunisal; Humans; In Vitro Techniques; Indomethacin; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Prostaglandin Antagonists; Salicylates; Sodium Salicylate | 1983 |
Salicylic acid plasma levels following multiple doses of Norgesic Forte and aspirin.
Topics: Adult; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Female; Humans; Kinetics; Male; Orphenadrine; Salicylates; Salicylic Acid | 1983 |
The effect of the non-steroidal anti-inflammatory drug choline magnesium trisalicylate on gastric mucosal cell exfoliation.
Topics: Adult; Aspirin; Choline; Female; Gastric Mucosa; Humans; Male; Random Allocation; Salicylates; Salicylic Acid | 1984 |
Partial purification and characterization of a microsomal carboxylesterase specific for salicylate esters from guinea-pig liver.
Topics: Animals; Aspirin; Carboxylesterase; Carboxylic Ester Hydrolases; Esters; Female; Guinea Pigs; Kinetics; Male; Microsomes, Liver; Molecular Weight; Nitrophenols; Salicylates; Substrate Specificity | 1984 |
Stabilized normal-phase high-performance liquid chromatographic analysis of aspirin and salicylic acid in solid pharmaceutical dosage forms.
Topics: Antacids; Aspirin; Buffers; Chromatography, High Pressure Liquid; Drug Stability; Salicylates; Salicylic Acid; Tablets | 1984 |
Interaction between frusemide and aspirin.
Topics: Adult; Aspirin; Diuresis; Female; Furosemide; Humans; Male; Natriuresis; Potassium; Salicylates; Salicylic Acid | 1984 |
Laryngeal edema as the only symptom of hypersensitivity to salicylic acid and other substances.
Topics: Adult; Aspirin; Drug Hypersensitivity; Female; Hoarseness; Humans; Laryngeal Edema; Male; Salicylates | 1984 |
[Effects of acetylsalicylic acid on partial functions of human thrombocytes are not inhibited in vivo by salicylic acid].
Topics: Administration, Oral; Adult; Aspirin; Blood Platelets; Humans; Male; Platelet Aggregation; Salicylates | 1984 |
Aspirin and Reye's syndrome. How strong an association?
Topics: Aspirin; Child; Child, Preschool; Diagnosis, Differential; Drug Labeling; Humans; Infant; Research Design; Retrospective Studies; Reye Syndrome; Salicylates | 1984 |
Plasma levels of salicylate and aspirin in healthy volunteers: relevance to drug interaction on platelet function.
Topics: Adult; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Platelet Aggregation; Salicylates; Sodium Salicylate; Thromboxane B2; Time Factors | 1984 |
Effect of oral 16,16-dimethyl prostaglandin E2 on gastric mucosal salicylate concentration in the rat.
Topics: Administration, Oral; Animals; Aspirin; Chromatography, High Pressure Liquid; Female; Gastric Mucosa; Injections, Intravenous; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Stomach Ulcer | 1984 |
Fatal hemorrhage from minor trauma following massive salicylate ingestion.
Topics: Alcoholism; Aspirin; Death, Sudden; Hemorrhage; Humans; Lung Diseases; Male; Mediastinal Diseases; Middle Aged; Purpura; Salicylates; Thrombocytopenia; Wounds, Nonpenetrating | 1984 |
Placental drug transfer in near-term ewes: acetylsalicylic and salicylic acid.
Topics: Animals; Aspirin; Computers; Female; Isotope Labeling; Kinetics; Maternal-Fetal Exchange; Models, Biological; Pregnancy; Salicylates; Salicylic Acid; Sheep | 1984 |
Effects of acetylsalicylic acid on human platelet function in vivo at salicylate steady state.
Topics: Adult; Aspirin; Collagen; Humans; Male; Platelet Aggregation; Platelet Function Tests; Salicylates; Salicylic Acid | 1984 |
Hemostasis, Prostacyclin and Preeclampsia.
Topics: Aspirin; Dipyridamole; Epoprostenol; Female; Hemostasis; Humans; Imidazoles; Pre-Eclampsia; Pregnancy; Prostaglandins; Salicylates | 1982 |
[Action of some salicylates associated with other non-steroidal anti-inflammatory drugs on the release of prostacyclin from the gastric mucosa of the rat].
Topics: Animals; Aspirin; Biological Assay; Diflunisal; Epoprostenol; Gastric Mucosa; Humans; Indomethacin; Male; Platelet Aggregation; Prostaglandins; Rats; Salicylates; Sodium Salicylate | 1982 |
Arachidonate metabolism via lipoxygenase and 12L-hydroperoxy-5,8,10,14-icosatetraenoic acid peroxidase sensitive to anti-inflammatory drugs.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Blood Platelets; Humans; Hydroxy Acids; Indomethacin; Leukotrienes; Lipoxygenase; Lipoxygenase Inhibitors; Peroxidases; Salicylates | 1980 |
Aspirin absorption from a feeding jejunostomy.
Topics: Aged; Aspirin; Enteral Nutrition; Half-Life; Humans; Intestinal Absorption; Jejunum; Male; Salicylates | 1980 |
Inhibition of Aspergillus growth and aflatoxin release by derivatives of benzoic acid.
Topics: Acrolein; Aflatoxins; Aspergillus; Aspergillus flavus; Aspirin; Benzoates; Benzocaine; Cinnamates; Coumaric Acids; ortho-Aminobenzoates; Salicylates | 1980 |
Salicylic acid inhibition of the irreversible effect of acetylsalicyclic aicd on prostaglandin synthetase may be due to competition for the enzyme cationic binding site.
Topics: Arachidonic Acids; Aspirin; Binding, Competitive; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Ferrous Compounds; Models, Chemical; Salicylates; Spectrophotometry | 1981 |
Enteric-coated aspirin in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Gold Sodium Thiomalate; Humans; Hydroxychloroquine; Penicillamine; Salicylates; Tablets, Enteric-Coated | 1981 |
Salicylate-aspirin interaction in the rat. Evidence that salicylate accumulating during aspirin administration may protect vascular prostacyclin from aspirin-induced inhibition.
Topics: Animals; Aspirin; Biotransformation; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Salicylates; Salicylic Acid | 1981 |
Delayed coma associated with salicylate intoxication.
Topics: Aspirin; Brain Edema; Child, Preschool; Coma; Female; Humans; Infant; Mannitol; Salicylates; Time Factors | 1982 |
Interaction between valproic acid and aspirin in epileptic children: serum protein binding and metabolic effects.
Topics: Aspirin; Blood Proteins; Child; Child, Preschool; Drug Interactions; Epilepsy; Female; Humans; Kinetics; Male; Protein Binding; Salicylates; Valproic Acid | 1982 |
Salicylic acid blocks indomethacin- and aspirin-induced cyclo-oxygenase inhibition in rat gastric mucosa.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dinoprost; Drug Interactions; Gastric Mucosa; Indomethacin; Male; Prostaglandin Antagonists; Prostaglandins F; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid | 1982 |
Effect of acetaminophen and salicylate on aspirin-induced inhibition of human platelet cyclo-oxygenase.
Topics: Acetaminophen; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Salicylates; Thromboxane B2 | 1982 |
Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique.
Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Aspirin; Male; Methods; Platelet Aggregation; Rats; Rats, Inbred Strains; Salicylates; Thromboxane B2; Thromboxanes | 1982 |
Effect of aspirin and sodium salicylate on thrombosis, fibrinolysis, prothrombin time, and platelet survival In rabbits with indwelling aortic catheters.
Topics: Animals; Aorta; Aspirin; Blood Coagulation; Blood Platelets; Catheterization; Catheters, Indwelling; Cell Survival; Fibrinolysis; Heparin; Male; Platelet Aggregation; Prothrombin Time; Rabbits; Salicylates; Sodium Salicylate; Thrombosis | 1983 |
Determination of salicylic acid in aspirin powder by second derivative ultraviolet spectrometry.
Topics: Aspirin; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet | 1983 |
Determination of acetylsalicylic acid and metabolites in biological fluids by high-performance liquid chromatography.
Topics: Animals; Aspirin; Chromatography, High Pressure Liquid; Gentisates; Hippurates; Humans; Kinetics; Male; Rabbits; Salicylates; Salicylic Acid; Specimen Handling | 1983 |
Modulation of natural killer activity by aspirin: I. In vitro effect of aspirin.
Topics: Aspirin; Cell Separation; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Humans; Interferon Type I; Killer Cells, Natural; Salicylates; Serum Albumin | 1983 |
Thermal decomposition of aspirin: formation of linear oligomeric salicylate esters.
Topics: Aspirin; Drug Stability; Hot Temperature; Salicylates | 1983 |
Plasma levels of acetylsalicylic acid and salicylic acid after oral ingestion of plain and buffered acetylsalicylic acid in relation to bleeding time and thrombocyte function.
Topics: Adult; Aspirin; Bleeding Time; Blood Coagulation; Blood Platelets; Buffers; Humans; Kinetics; Male; Platelet Aggregation; Platelet Function Tests; Salicylates; Salicylic Acid | 1983 |
Protection from arrhythmias of cultured heart cells by nonsteroidal antiinflammatory drugs.
Topics: Animals; Animals, Newborn; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Aspirin; Cells, Cultured; Indomethacin; Rats; Salicylates; Salicylic Acid; Sulfinpyrazone; Time Factors | 1983 |
Distribution of the acetyl compared with the salicyl moiety of acetylsalicylic acid. Acetylation of macromolecules in organs wherein side-effects are manifest.
Topics: Acetates; Acetylation; Animals; Aspirin; Chemical Phenomena; Chemistry; Glycoproteins; Kinetics; Lipid Metabolism; Male; Proteins; Rats; Rats, Inbred Strains; Salicylates; Tissue Distribution | 1983 |
Measurement of true salicylate concentrations in serum from patients with Reye's syndrome.
Topics: Aspirin; Blood Proteins; Child; Chlorides; Chromatography, Thin Layer; False Positive Reactions; Ferric Compounds; Humans; Palmitates; Protein Binding; Reye Syndrome; Salicylates; Spectrophotometry | 1983 |
Distribution of salicylate in lens and intraocular fluids and its effect on cataract formation.
Topics: Animals; Aqueous Humor; Aspirin; Cataract; Crystallins; Diabetes Complications; Galactose; Humans; Lens, Crystalline; Rabbits; Rats; Salicylates; Sodium Salicylate; Vitreous Body | 1983 |
In vitro and in vivo evaluation of two preparations of activated charcoal as adsorbents of aspirin.
Topics: Adsorption; Adult; Aspirin; Biological Availability; Charcoal; Female; Humans; Male; Salicylates; Salicylic Acid; Time Factors | 1983 |
Combined embryotoxic action of toluene, a widely used industrial chemical, and acetylsalicylic acid (aspirin).
Topics: Abnormalities, Drug-Induced; Amniotic Fluid; Animals; Aspirin; Drug Interactions; Embryo, Mammalian; Female; Gestational Age; Glycine; Pregnancy; Rats; Salicylates; Salicylic Acid; Teratogens; Toluene | 1983 |
[Treatment of painful muscular disorders of various degrees of severity. Comparison of 2 new suppository preparations].
Topics: Aspirin; Codeine; Diphenhydramine; Drug Combinations; Female; Gout; Humans; Male; Meprobamate; Middle Aged; Muscle Rigidity; Nerve Compression Syndromes; Nicotinic Acids; Osteoarthritis; Pain; Plant Extracts; Salicylamides; Salicylates; Spinal Nerve Roots; Suppositories | 1983 |
Sensitive salicylate assay in plasma with a 'reversed' Berthelot's reaction.
Topics: Aspirin; Chemical Phenomena; Chemistry; Chloramines; Colorimetry; Humans; Pyruvates; Pyruvic Acid; Salicylates; Salicylic Acid; Time Factors | 1983 |
Influence of food on aspirin absorption from tablets and buffered solutions.
Topics: Adult; Aspirin; Buffers; Food; Humans; Intestinal Absorption; Male; Salicylates; Salicylic Acid; Solutions; Tablets | 1983 |
Salicylates and Reye's syndrome.
Topics: Aspirin; Humans; Reye Syndrome; Salicylates; Terminology as Topic | 1983 |
Salicylate interferes in vivo with aspirin-induced inhibition of platelet and vascular prostaglandin generation in rats.
Topics: Animals; Aspirin; Blood Platelets; Drug Interactions; Prostaglandins; Rats; Salicylates | 1982 |
Comparative evaluation of gastrointestinal blood loss in the feces of rats following Pepto-Bismol liquid and aspirin administration.
Topics: Animals; Aspirin; Bismuth; Feces; Gastrointestinal Hemorrhage; Male; Occult Blood; Organometallic Compounds; Rats; Salicylates | 1980 |
Are all aspirins really alike? A comparison of gastric ulcerogenicity with bio-efficacy in rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biological Availability; Buffers; Female; Rats; Salicylates; Stomach Ulcer; Therapeutic Equivalency | 1980 |
Pharmacological studies in the rat with [2-(1,3-didecanoyloxy)-propyl]2-acetyloxybenzoate (A-45474): an aspirin pro-drug with negligible gastric irritation.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biological Availability; Carrageenan; Delayed-Action Preparations; Edema; Injections, Intravenous; Intestinal Absorption; Male; Rats; Salicylates; Stomach; Time Factors; Triglycerides | 1980 |
Acetylsalicylic acid-induced gastrointestinal bleeding determined by a 51Cr method on a day-to-day basis.
Topics: Adult; Aspirin; Chromium Radioisotopes; Double-Blind Method; Feces; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Salicylates; Time Factors | 1980 |
Anti-inflammatory/anti-pyretic salicylic acid esters with low gastric ulcerogenic activity.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Evaluation, Preclinical; Female; Male; Rats; Salicylates; Stomach Ulcer; Structure-Activity Relationship; Swine | 1980 |
Increased serum salicylate metabolites with age in patients receiving chronic acetylsalicylic acid therapy.
Topics: Adult; Age Factors; Aspirin; Humans; Middle Aged; Rheumatic Diseases; Salicylates | 1981 |
Comparative tissue absorption of oral 14C-aspirin and topical triethanolamine 14C-salicylate in human and canine knee joints.
Topics: Absorption; Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dogs; Humans; Knee Joint; Male; Middle Aged; Salicylates; Synovial Fluid; Time Factors; Tissue Distribution | 1982 |
Efficacy, disposition and pharmacodynamics of aspirin, acetaminophen and choline salicylate in young febrile children.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Choline; Drug Combinations; Female; Fever; Humans; Kinetics; Male; Pulse; Respiration; Salicylates | 1982 |
Diflunisal (Dolobid).
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dextropropoxyphene; Diflunisal; Humans; Salicylates | 1982 |
[Relation between the administration of salicylates in various viral infections and the appearance of Reye's syndrome].
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Fever; Humans; Reye Syndrome; Salicylates; Virus Diseases | 1982 |
Effect of some organic acid salts of tris(hydroxymethyl)aminomethane in the incubation step on plasma renin activity.
Topics: Acetates; Angiotensin I; Aspirin; Benzoates; Buffers; Humans; Hydrogen-Ion Concentration; Maleates; Phenoxyacetates; Radioimmunoassay; Renin; Salicylates; Tromethamine | 1980 |
Rebound rise in renin concentrations after cessation of salicylates.
Topics: Aspirin; Blood Pressure; Body Weight; Humans; Renin; Salicylates; Time Factors | 1980 |
Aspirin and analgesic nephropathy.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Creatinine; Female; History, 17th Century; Humans; Kidney; Kidney Diseases; Male; Nephritis, Interstitial; Proteinuria; Random Allocation; Salicylates; Time Factors | 1982 |
In vivo and in vitro studies on the binding of salicylate to human plasma proteins: evidence for one type of binding site.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Binding Sites; Blood Proteins; Female; Humans; In Vitro Techniques; Kinetics; Male; Middle Aged; Protein Binding; Salicylates; Salicylic Acid | 1982 |
Effects of sodium salicylate and acetylsalicylic acid on intramural pH and ulceration of rabbit antral mucosa.
Topics: Animals; Aspirin; Bicarbonates; Gastric Mucosa; Hydrogen-Ion Concentration; Peptic Ulcer; Pyloric Antrum; Rabbits; Salicylates; Sodium Salicylate | 1982 |
Endogenous gastric mucosal prostaglandins: their role in mucosal integrity.
Topics: Animals; Aspirin; Biological Transport, Active; Dogs; Gastric Mucosa; Prostaglandins; Salicylates; Salicylic Acid; Sodium | 1982 |
Comparable serum salicylate concentrations from choline magnesium trisalicylate, aspirin, and buffered aspirin in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Choline; Female; Humans; Male; Middle Aged; Salicylates | 1982 |
Improved liquid-chromatography of aspirin, salicylate, and salicyluric acid in plasma, with a modification for determining aspirin metabolites in urine.
Topics: Aspirin; Chromatography, High Pressure Liquid; Glycine; Hippurates; Humans; Reference Values; Salicylates | 1982 |
[Diflunisal inhibits inflammation and protects the stomach].
Topics: Aspirin; Biological Availability; Chemical Phenomena; Chemistry; Diflunisal; Gastric Mucosa; Gastritis; Humans; Salicylates | 1982 |
Gastric emptying and absorption of acetylsalicylic acid administered as enteric-coated micro-granules.
Topics: Adult; Aspirin; Capsules; Delayed-Action Preparations; Gastric Emptying; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Male; Salicylates; Salicylic Acid | 1982 |
Determination of related compounds in aspirin by liquid chromatography.
Topics: Aspirin; Chromatography, Liquid; Salicylates; Salicylic Acid; Tablets | 1982 |
Treatment of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Humans; Salicylates | 1982 |
Bioavailability of acetylsalicylic acid and salicylic acid from rapid-and slow-release formulations, and in combination with dipyridamol.
Topics: Adult; Aspirin; Biological Availability; Delayed-Action Preparations; Dipyridamole; Female; Humans; Kinetics; Male; Salicylates; Salicylic Acid | 1982 |
Aspirin treatment of migraine attacks: plasma drug level data.
Topics: Adolescent; Adult; Aspirin; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; Salicylates; Time Factors | 1982 |
Testing for drugs inhibiting the formation of gastric ulcers.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Cold Temperature; Copper; Indomethacin; Mucus; Organometallic Compounds; Rats; Rats, Inbred Strains; Receptors, Histamine H2; Salicylates; Stomach Ulcer; Stress, Physiological | 1982 |
Species differences in hypocalcemia induced by acetyl-salicylic acid.
Topics: Animals; Aspirin; Calcitonin; Dogs; Female; Guinea Pigs; Hypocalcemia; Male; Mice; Mice, Inbred Strains; Rabbits; Rats; Rats, Inbred Strains; Salicylates; Species Specificity | 1982 |
Inhibition of anaerobic glycolysis in bovine retina extracts by salicylate and acetylsalicylate.
Topics: Animals; Aspirin; Cattle; Glucose; Glycolysis; In Vitro Techniques; Lactates; Lactic Acid; Oxygen; Retina; Salicylates; Salicylic Acid | 1982 |
[Studies on the pharmacological bases of fetal toxicity of drugs. (I). Relation of fetal toxicity and tissue concentration of acetylsalicylic acid with pyrogen in pregnant rats].
Topics: Abnormalities, Drug-Induced; Adenosine Triphosphate; Animals; Aspirin; Body Weight; Drug Synergism; Female; Fetus; Humans; Infant, Newborn; Lipopolysaccharides; Male; Maternal-Fetal Exchange; Pregnancy; Pyrogens; Rats; Salicylates; Salicylic Acid; Tissue Distribution | 1982 |
Aspirin--a national survey V: Determination of aspirin and impurities in enteric coated tablets and suppository formulations and in vitro dissolution of enteric coated tablets.
Topics: Aspirin; Chromatography, Thin Layer; Drug Contamination; Salicylates; Salicylic Acid; Solubility; Suppositories; Tablets, Enteric-Coated; United States | 1982 |
[Gas chromatographic determination of acetylsalicylic acid and salicylic acid acid in serum].
Topics: Aspirin; Chromatography, Gas; Humans; Salicylates | 1982 |
Solid-state stability of aspirin in the presence of excipients: kinetic interpretation, modeling, and prediction.
Topics: Aspirin; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Stability; Excipients; Kinetics; Models, Chemical; Salicylates | 1982 |
Perinatal pharmacokinetics of acetylsalicylic acid.
Topics: Aspirin; Female; Fetal Blood; Humans; Infant, Newborn; Kinetics; Obstetric Labor, Premature; Pregnancy; Salicylates | 1982 |
The transmural gastric potential difference in combination with pharmacokinetic profiles. A new approach to combine kinetic and dynamic properties of compounds.
Topics: Adolescent; Adult; Aspirin; Buffers; Double-Blind Method; Drug Combinations; Female; Gastric Mucosa; Humans; Kinetics; Male; Membrane Potentials; Models, Biological; Salicylates; Salicylic Acid | 1982 |
Systemic availability of acetylsalicylic acid in human subjects after oral ingestion of three different formulations.
Topics: Administration, Oral; Aspirin; Biological Availability; Biotransformation; Delayed-Action Preparations; Humans; Kinetics; Salicylates; Salicylic Acid | 1982 |
[In vivo drug release from microencapsulated acetylsalicylic acid with simultaneous alcohol uptake].
Topics: Adult; Alcoholic Beverages; Aspirin; Capsules; Delayed-Action Preparations; Drug Interactions; Ethanol; Female; Humans; Male; Microspheres; Middle Aged; Salicylates; Time Factors; Wine | 1980 |
Effect of non-steroid anti-inflammatory drugs in experimental myocardial infarction in rats.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Coronary Vessels; Indomethacin; Male; Myocardial Infarction; Rats; Salicylates; Sulfinpyrazone | 1981 |
Simultaneous GLC analysis of aspirin and nonaspirin salicylates in pharmaceutical tablet formulations.
Topics: Aluminum Hydroxide; Aspirin; Chromatography, Gas; Hydrolysis; Magnesium Hydroxide; Salicylates; Tablets | 1981 |
Bio-distribution in rats of some salicylates with low gastric ulcerogenicity.
Topics: Animals; Aspirin; Male; Rats; Salicylates; Stomach Ulcer; Tissue Distribution | 1980 |
Anti-inflammatory agents in arthritis.
Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Bursitis; Humans; Osteoarthritis; Salicylates; Spondylitis; Tendinopathy | 1981 |
Measurement and pharmacokinetics of acetylsalicylic acid by a novel high performance liquid chromatographic assay.
Topics: Aspirin; Chromatography, High Pressure Liquid; Half-Life; Humans; Intestinal Absorption; Kinetics; Physostigmine; Salicylates; Tissue Distribution | 1980 |
Sublimation losses of salicylic acid from plasma during analysis.
Topics: Aspirin; Chromatography, High Pressure Liquid; Humans; Salicylates | 1981 |
Determination of drug stability in aspirin tablet formulations by high-pressure liquid chromatography.
Topics: Aspirin; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Stability; Salicylates | 1981 |
Salicylate toxicity following therapeutic doses in young children.
Topics: Acute Kidney Injury; Aspirin; Child, Preschool; Female; Humans; Infant; Male; Pulmonary Edema; Renal Dialysis; Salicylates | 1981 |
Pharmacology of human spontaneous monocyte-mediated cytotoxicity. I. Enhancement by salicylates and steroids.
Topics: Anti-Inflammatory Agents; Aspirin; Cytotoxicity, Immunologic; Humans; Hydrocortisone; Indomethacin; Killer Cells, Natural; Monocytes; Prostaglandins E; Salicylates | 1981 |
Ketoprofen-aspirin interactions.
Topics: Adult; Aspirin; Blood Proteins; Drug Interactions; Humans; Ketoprofen; Kinetics; Male; Phenylpropionates; Protein Binding; Salicylates | 1981 |
Salicylate metabolite kinetics after several salicylates.
Topics: Adult; Aspirin; Blood Proteins; Female; Gentisates; Glycine; Hippurates; Humans; Kinetics; Male; Models, Biological; Protein Binding; Salicylates; Sodium Salicylate | 1981 |
Spectrofluorometric determination of acetylsalicylic acid, salicylamide, and salicyclic acid as an impurity in pharmaceutical preparations.
Topics: Acetaminophen; Aspirin; Buffers; Caffeine; Drug Combinations; Drug Contamination; Salicylamides; Salicylates; Salicylic Acid; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1981 |
[Rudzki's diet in the treatment of aspirin hypersensitivity].
Topics: Adolescent; Adult; Aged; Aspirin; Azo Compounds; Benzoates; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Salicylates | 1980 |
Rational approaches to chemotherapy: antisickling agents.
Topics: Anemia, Sickle Cell; Aspirin; Chemical Phenomena; Chemistry; Hemoglobin, Sickle; Humans; Protein Binding; Protein Conformation; Salicylates; Solubility; Structure-Activity Relationship | 1981 |
Misleading results in cases of coexisting acetaminophen and salicylate overdose.
Topics: Acetaminophen; Adult; Aspirin; Colorimetry; Female; Humans; Salicylates | 1980 |
Kinetics of aspirin, salicylic acid, and salicyluric acid following oral administration of aspirin as a tablet and two buffered solutions.
Topics: Absorption; Administration, Oral; Adult; Aspirin; Buffers; Glycine; Half-Life; Hippurates; Humans; Kinetics; Male; Regression Analysis; Salicylates; Tablets | 1981 |
Improved delivery through biological membranes IX: Kinetics and mechanism of hydrolysis of methylsulfinymethyl 2-acetoxybenzoate and related aspirin prodrugs.
Topics: Aspirin; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Salicylates; Solubility; Temperature | 1981 |
Improved delivery through biological membranes XD: Percutaneous absorption and metabolism of methylsulfinylmethyl 2-acetoxybenzoate and related aspirin prodrugs.
Topics: Animals; Aspirin; Biotransformation; Female; Half-Life; In Vitro Techniques; Liver; Male; Mice; Mice, Nude; Rats; Salicylates; Skin Absorption | 1981 |
High unbound fraction of salicylate in plasma during intoxication.
Topics: Adolescent; Aspirin; Female; Humans; Salicylates | 1981 |
[Pharmacology of salicylates. V. Comparison of absorption and excretion of acetylsalicylic acid in infants and older children].
Topics: Adolescent; Aspirin; Child; Humans; Infant; Infant, Newborn; Salicylates | 1981 |
Salicylate-aspirin interaction and thrombosis prevention trials.
Topics: Animals; Aspirin; Drug Interactions; Rats; Salicylates; Thrombosis | 1981 |
Mechanisms of Forssman-induced bronchospasm and their inhibition.
Topics: Animals; Aspirin; Blood Platelets; Bronchial Spasm; Complement System Proteins; Forssman Antigen; Guinea Pigs; Immune Sera; Indomethacin; Neuraminidase; Pressure; Salicylates; Sulfinpyrazone | 1981 |
High-pressure liquid chromatographic determination of acetylsalicylic acid, salicylic acid, diflunisal, indomethacin, indoprofen and indobufen.
Topics: Anti-Inflammatory Agents; Aspirin; Chromatography, High Pressure Liquid; Diflunisal; Humans; Indoles; Indomethacin; Indoprofen; Isoindoles; Phenylbutyrates; Salicylates | 1981 |
Gastric cytoprotection by sodium salicylate.
Topics: Animals; Aspirin; Ethanol; Gastric Mucosa; Indomethacin; Male; Rats; Salicylates; Salicylic Acid; Stomach Ulcer; Structure-Activity Relationship | 1981 |
Comparative bioavailability of sustained-release and uncoated aspirin tablets.
Topics: Adult; Aspirin; Biological Availability; Delayed-Action Preparations; Female; Humans; Kinetics; Male; Salicylates; Tablets; Time Factors | 1981 |
Absorption, biotransformation, and pharmacokinetics of salicylsalicylic acid in humans.
Topics: Absorption; Adult; Aspirin; Biotransformation; Chromatography, High Pressure Liquid; Half-Life; Humans; Hydrolysis; Kinetics; Male; Middle Aged; Salicylates | 1981 |
General model for dissolution rates of n-component, nondisintegrating spheres.
Topics: Aspirin; Caffeine; Chemical Phenomena; Chemistry, Physical; Drug Combinations; Kinetics; Models, Chemical; Phenacetin; Salicylates; Salicylic Acid; Solubility | 1981 |
Relative bioavailability of aspirin gum.
Topics: Adolescent; Adult; Aspirin; Biological Availability; Chewing Gum; Humans; Male; Salicylates; Time Factors | 1981 |
[Comparative study of the in vitro anti-aggregating action of various salicylic derivatives].
Topics: Animals; Aspirin; Chemical Phenomena; Chemistry; Organophosphates; Platelet Aggregation; Rats; Salicylates | 1981 |
Salicylate toxicity following therapeutic doses in children.
Topics: Aspirin; Child; Humans; Salicylates | 1981 |
[Acetylsalicylic acid-induced hepatotoxicity].
Topics: Adult; Alkaline Phosphatase; Arthritis, Juvenile; Aspirin; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Diseases; Salicylates; Transaminases | 1981 |
Aspirin-induced gastric bleeding stops despite rising plasma salicylate.
Topics: Aspirin; Female; Gastric Mucosa; Humans; Kinetics; Male; Salicylates; Stomach Ulcer | 1980 |
High-pressure liquid chromatographic determination of salicylic acid in aspirin powder and pharmaceutical dosage forms.
Topics: Aspirin; Chromatography, High Pressure Liquid; Dosage Forms; Powders; Salicylates | 1980 |
Simultaneous liquid-chromatographic quantitation of salicylic acid, salicyluric acid, and gentisic acid in urine.
Topics: Aspirin; Chromatography, High Pressure Liquid; Gentisates; Glycine; Hippurates; Humans; Kinetics; Salicylates | 1980 |
Metabolism of salicylate during chronic aspirin therapy.
Topics: Arthritis, Rheumatoid; Aspirin; Female; Humans; Hydrogen-Ion Concentration; Male; Salicylates; Saliva; Time Factors | 1980 |
Glycerides as prodrugs. 2. 1,3-Dialkanoyl-2-(2-methyl-4-oxo-1,3-benzodioxan-2-yl)glycerides (cyclic aspirin triglycerides) as antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Edema; Male; Rats; Salicylates; Stomach Ulcer; Triglycerides | 1980 |
Clinical experience--NSAID.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Humans; Salicylates | 1980 |
Relationship between saliva salicylate concentration and free or total salicylate concentration in serum of children with juvenile rheumatoid arthritis.
Topics: Adolescent; Arthritis, Juvenile; Aspirin; Blood Proteins; Child; Child, Preschool; Female; Heparin; Humans; Individuality; Male; Protein Binding; Salicylates; Saliva; Time Factors | 1980 |
Salicylate therapy in juvenile rheumatoid arthritis. Dose, serum level, and toxicity.
Topics: Adolescent; Arthritis, Juvenile; Aspirin; Child; Child, Preschool; Humans; Infant; Prospective Studies; Salicylates | 1980 |
Aspirin--a national survey I: Semiautomated determination of aspirin in bulk and tablet formulations and salicyclic acid in tablet formulations.
Topics: Aspirin; Autoanalysis; Colorimetry; Hydrolysis; Salicylates; Spectrophotometry, Ultraviolet; Tablets | 1980 |
Aspirin--a national survey II: Determination of salicylic acid in bulk aspirin and aspirin formulations by high-pressure liquid chromatography using a fluorescence detector.
Topics: Aspirin; Chromatography, High Pressure Liquid; Fluorometry; Salicylates; Tablets | 1980 |
Aspirin--a national survey III: Determination of impurities in bulk aspirin and aspirin formulations by high-pressure liquid chromatography and spectrophotometry.
Topics: Aspirin; Chromatography, High Pressure Liquid; Drug Contamination; Salicylates; Spectrophotometry | 1980 |
Indomethacin, salicylates and prostaglandin binding.
Topics: Arthritis, Rheumatoid; Aspirin; Humans; Indomethacin; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F; Protein Binding; Salicylates; Serum Albumin | 1980 |
Specific and sensitive method for the determination of aspirin and salicylic acid in plasma using reversed-phase high-performance liquid chromatography.
Topics: Aspirin; Chromatography, High Pressure Liquid; False Negative Reactions; Female; Humans; Salicylates; Specimen Handling | 1980 |
In vitro studies on the effect of salicylates on the synthesis of proteins by guinea pig gastric mucosal tissue.
Topics: Animals; Aspirin; Epithelial Cells; Epithelium; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Leucine; Male; Protein Biosynthesis; Salicylates | 1980 |
Comparison of intravenous and intragastric aspirin in production of antral gastric ulcers in cats.
Topics: Animals; Aspirin; Cats; Female; Histamine; Infusions, Parenteral; Male; Prostaglandins; Pyloric Antrum; Salicylates; Stomach Ulcer | 1980 |
Effects of aspirin and related drugs in vitamin E-deficient rats.
Topics: Animals; Aspirin; Blood Cell Count; Female; Fetal Death; Hematocrit; Hemoglobins; Hemolysis; Male; Pregnancy; Pregnancy Complications; Prostaglandins; Rats; Salicylates; Testis; Vitamin E Deficiency | 1980 |
Salicylic acid in aspirin formulations.
Topics: Aspirin; Chromatography, High Pressure Liquid; Salicylates | 1980 |
Simultaneous determination of aspirin and salicylic acid in bulk aspirin and in plain, buffered, and enteric-coated tablets by high-pressure liquid chromatography with UV and fluorescence detectors.
Topics: Aspirin; Chromatography, High Pressure Liquid; Salicylates; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tablets; Tablets, Enteric-Coated | 1980 |
Clinical pharmacokinetics of salicylates: a re-assessment.
Topics: Analgesics; Aspirin; Humans; Kinetics; Salicylates | 1980 |
Excretion of salicylic acid into tears following oral administration of aspirin.
Topics: Administration, Oral; Adult; Arthritis, Rheumatoid; Aspirin; Chromatography, High Pressure Liquid; Humans; Salicylates; Tears | 1980 |
Lack of platelet effect with the aspirin analog, salsalate.
Topics: Arthritis; Aspirin; Bleeding Time; Blood Platelets; Humans; Platelet Aggregation; Salicylates; Serotonin | 1980 |
[The value of serum salicylate determination in patients with rheumatoid arthritis (author's transl)].
Topics: Adult; Arthritis, Rheumatoid; Aspirin; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Rheumatoid Factor; Salicylates; Tinnitus | 1980 |
High-pressure liquid chromatographic determination of salicylsalicylic acid, aspirin, and salicylic acid in human plasma and urine.
Topics: Anti-Inflammatory Agents; Aspirin; Chromatography, High Pressure Liquid; Humans; Male; Salicylates | 1980 |
Effects of aspirin and acetaminophen on the liver.
Topics: Acetaminophen; Adolescent; Adult; Alcoholism; Arthritis, Juvenile; Aspirin; Child; Female; Humans; Liver; Lupus Erythematosus, Systemic; Male; Salicylates | 1981 |
Acute and chronic effects of aspirin toxicity and their treatment.
Topics: Adolescent; Adult; Aged; Aspirin; Child; Child, Preschool; Fluid Therapy; Glucose; Humans; Infant; Middle Aged; Renal Dialysis; Salicylates; Water-Electrolyte Imbalance | 1981 |
The laboratory in the diagnosis and management of acetaminophen and salicylate intoxications.
Topics: Acetaminophen; Acetylcysteine; Acid-Base Imbalance; Aspirin; Child, Preschool; Female; Hepatic Encephalopathy; Humans; Infant; Liver; Male; Poisoning; Salicylates; Time Factors | 1980 |
Effect of multiple-dose activated charcoal on the clearance of high-dose intravenous aspirin in a porcine model.
Topics: Animals; Antidotes; Aspirin; Charcoal; Cross-Over Studies; Disease Models, Animal; Drug Evaluation, Preclinical; Metabolic Clearance Rate; Poisoning; Salicylates; Salicylic Acid; Swine; Time Factors | 1995 |
Pharmacokinetics and pharmacodynamics in copper deficiency. I. Antiinflammatory activity of aspirin.
Topics: Analysis of Variance; Animals; Aspirin; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Copper; Diet; Edema; Male; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid | 1994 |
Salicylate poisoning: two-dimensional J-resolved NMR urinalysis.
Topics: Adolescent; Aspirin; Female; Gentisates; Hippurates; Humans; Hydroxybenzoates; Magnetic Resonance Spectroscopy; Poisoning; Salicylates; Salicylic Acid | 1995 |
Aspirin, salicylate, sulfite and tartrazine induced bronchoconstriction. Safe doses and case definition in epidemiological studies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Bronchoconstriction; Drug Hypersensitivity; Environmental Exposure; Epidemiologic Methods; False Positive Reactions; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Salicylates; Salicylic Acid; Sulfites; Tartrazine | 1995 |
Growth inhibition of rat glioma cells in vitro and in vivo by aspirin.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Neoplasms; Cell Division; Female; Glioma; Hydrogen-Ion Concentration; Indomethacin; Male; Neoplasm Proteins; Neoplasm Transplantation; Piroxicam; Rats; Rats, Inbred F344; Salicylates; Tumor Cells, Cultured | 1995 |
Aspirin as a free radical scavenger: consequences for therapy of cerebrovascular ischemia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Cerebrovascular Disorders; Cyclooxygenase Inhibitors; Female; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Male; Neuroprotective Agents; Platelet Aggregation Inhibitors; Salicylates; Salicylic Acid | 1995 |
Protein binding of acetylsalicylic acid and salicylic acid in porcine and human serum.
Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Proteins; Drug Overdose; Esterases; Humans; In Vitro Techniques; Isotope Labeling; Pilot Projects; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Swine; Ultrafiltration | 1995 |
Aspirin, salicylate and gastrointestinal injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Detergents; Gastric Mucosa; Gastrointestinal Hemorrhage; Gels; Intestinal Mucosa; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phospholipids; Rats; Salicylates; Stomach Ulcer | 1995 |
Chronopharmacological study of acetylsalicylic acid in mice.
Topics: Analgesics; Animals; Aspirin; Body Temperature; Circadian Rhythm; Male; Mice; Mice, Inbred ICR; Pain Measurement; Salicylates; Salicylic Acid | 1995 |
Involvement of brain serotonergic system in the antinociceptive action of acetylsalicylic acid in the rat.
Topics: Analgesics; Animals; Aspirin; Behavior, Animal; Brain; Cerebral Cortex; Fenclonine; Injections, Intraperitoneal; Male; Pain Threshold; Pons; Rats; Rats, Wistar; Receptors, Serotonin; Salicylates; Serotonin | 1995 |
High-performance liquid chromatography-electrochemical determination of salicylate hydroxylation products as an in vivo marker of oxidative stress.
Topics: Adult; Aspirin; Calibration; Chromatography, High Pressure Liquid; Female; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Male; Oxidative Stress; Reproducibility of Results; Salicylates; Salicylic Acid; Thiobarbituric Acid Reactive Substances | 1995 |
Disposition kinetics of aspirin in female New Zealand white rabbits.
Topics: Animals; Aspirin; Body Weight; Chromatography, High Pressure Liquid; Female; Kinetics; Rabbits; Salicylates; Salicylic Acid | 1995 |
Aspirin and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain Ischemia; Cerebral Infarction; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Prospective Studies; Salicylates; Subarachnoid Hemorrhage; Time Factors; Tomography, X-Ray Computed | 1995 |
The quantitative determination of aspirin and its degradation products in a model solution aerosol.
Topics: Administration, Inhalation; Aerosols; Aspirin; Chemistry, Pharmaceutical; Chromatography; Reference Standards; Salicylates; Salicylic Acid; Solutions | 1995 |
Effects of triflusal and its main metabolite HTB on platelet interaction with subendothelium in healthy volunteers.
Topics: Adult; Animals; Aspirin; Blood Platelets; Endothelium, Vascular; Humans; Male; Perfusion; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Salicylates | 1995 |
Aspirin-induced asthma and artificial flavors.
Topics: Aspirin; Asthma; Flavoring Agents; Humans; Parabens; Salicylates; Toothpastes | 1994 |
Effects of nonsteroidal antiinflammatory drugs on ulcerogenesis and gastric secretion in pylorus-ligated rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Gastric Acid; Gastric Mucosa; Histamine; Ibuprofen; Indomethacin; Ligation; Male; Pepsinogens; Pylorus; Ranitidine; Rats; Rats, Sprague-Dawley; Salicylates; Stomach Ulcer | 1995 |
Zero-crossing first and second derivative synchronous fluorescence spectroscopic determination of aspirin metabolites in urine.
Topics: Aspirin; Hippurates; Humans; Indicators and Reagents; Salicylates; Salicylic Acid; Spectrometry, Fluorescence | 1994 |
Salicylamide reverses the aspirin-antagonistic effect of salicylic acid on rat platelet cyclooxygenase.
Topics: Animals; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Salicylamides; Salicylates; Salicylic Acid; Thromboxane B2 | 1994 |
Copper(II) interactions with nonsteroidal antiinflammatory agents. I. Salicylic acid and acetylsalicylic acid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cations, Divalent; Copper; Gastric Juice; Hydrogen-Ion Concentration; In Vitro Techniques; Models, Biological; Salicylates; Salicylic Acid | 1995 |
Potentiation by caffeine of the analgesic effect of aspirin in the pain-induced functional impairment model in the rat.
Topics: Animals; Aspirin; Caffeine; Drug Synergism; Female; Gentisates; Hindlimb; Hydroxybenzoates; Pain; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1994 |
Aspirin inhibits secretagogue-stimulated and postprandial pancreatic exocrine secretion in conscious rats.
Topics: Animals; Aspirin; Cholecystokinin; Dinoprostone; Food; Indomethacin; Male; Pancreas; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Secretin; Stimulation, Chemical | 1995 |
No aspirin in red wine.
Topics: Aspirin; Cardiovascular Diseases; Free Radical Scavengers; Humans; Salicylates; Salicylic Acid; Wine | 1994 |
Spectrofluorimetry at zero angle: determination of salicylic acid in an acetylsalicylic acid pharmaceutical formulation.
Topics: Aspirin; Chromatography, High Pressure Liquid; Drug Storage; Salicylates; Salicylic Acid; Spectrometry, Fluorescence | 1994 |
Use of isosbestic points of derivative absorption curves: the dissolution rate determination of aspirin.
Topics: Adsorption; Aspirin; Hydrolysis; Kinetics; Salicylates; Salicylic Acid; Solubility; Spectrophotometry, Ultraviolet | 1994 |
[Determination of trace amounts of salicylic acid and acetylsalicylic acid in polopirin and other drugs containing acetylsalicylic acid].
Topics: Aspirin; Chromatography, Liquid; Salicylates; Salicylic Acid | 1993 |
Comparison of assay methods by second-derivative spectroscopy, colorimetry and fluorescence spectroscopy of salicylic acid in aspirin preparations with a high-performance liquid chromatographic method.
Topics: Aspirin; Chromatography, High Pressure Liquid; Colorimetry; Reproducibility of Results; Salicylates; Salicylic Acid; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tablets | 1994 |
Acetylsalicylic acid--inducer of cytochrome P-450 2E1?
Topics: Animals; Aspirin; Carboxyhemoglobin; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Methylene Chloride; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Rats; Rats, Wistar; Salicylates; Salicylic Acid | 1994 |
Comparison of three new spectrophotometric methods for simultaneous determination of aspirin and salicylic acid in tablets without separation of pharmaceutical excipients.
Topics: Absorption; Aspirin; Chemistry, Pharmaceutical; Excipients; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Salicylates; Spectrophotometry, Ultraviolet; Tablets | 1994 |
N-acetyl-beta-D-glucosaminidase (NAG) and alanine aminopeptidase (AAP) excretion after acute administration of acetaminophen, salsalate and aspirin in rats.
Topics: Acetaminophen; Acetylglucosaminidase; Administration, Oral; Aminopeptidases; Animals; Aspirin; CD13 Antigens; Diuresis; Female; Kidney; Potassium; Rats; Rats, Wistar; Salicylates; Salicylic Acid; Sodium; Spectrophotometry, Atomic | 1993 |
Studies on the reactivity of acyl glucuronides--VII. Salicyl acyl glucuronide reactivity in vitro and covalent binding of salicylic acid to plasma protein of humans taking aspirin.
Topics: Animals; Aspirin; Buffers; Glucuronates; Half-Life; Humans; Hydrogen-Ion Concentration; Rats; Salicylates; Salicylic Acid; Serum Albumin | 1994 |
Effects of acetylsalicylic acid on pulmonary vascular tone and membrane permeability in blood-perfused dog lung.
Topics: 6-Ketoprostaglandin F1 alpha; Airway Resistance; Animals; Aspirin; Blood Pressure; Capillary Permeability; Dogs; Extravascular Lung Water; Female; Leukotrienes; Male; Muscle, Smooth, Vascular; Organ Size; Perfusion; Pulmonary Circulation; Salicylates; Salicylic Acid; Thromboxane B2; Vascular Resistance | 1993 |
Investigation of the influence of acetylsalicylic acid on the steady state of long-term therapy with theophylline in elderly male patients with normal renal function.
Topics: Aged; Aged, 80 and over; Aspirin; Drug Interactions; Humans; Kidney; Male; Middle Aged; Risk Factors; Salicylates; Tablets, Enteric-Coated; Theophylline | 1994 |
Aspirin-like drugs inhibit neuronally evoked responses in isolated guinea-pig ileum.
Topics: Acetylcholine; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzydamine; Cyclooxygenase Inhibitors; Guinea Pigs; Ileum; Indomethacin; Isotonic Contraction; Male; Muscle, Smooth; Naloxone; Parasympathetic Nervous System; Receptors, Opioid; Salicylates; Salicylic Acid; Sincalide | 1993 |
Slow release aspirin in the elderly.
Topics: Aged; Aged, 80 and over; Aspirin; Delayed-Action Preparations; Female; Humans; Male; Salicylates; Salicylic Acid; Vascular Diseases | 1994 |
Gallbladder contractility in aspirin- and cholesterol-fed prairie dogs.
Topics: Animals; Aspirin; Cholesterol; Crystallization; Diet; Dose-Response Relationship, Drug; Gallbladder; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins; Salicylates; Salicylic Acid; Sciuridae; Sincalide | 1994 |
Plasma acetylsalicylic acid and salicylic acid levels during aspirin provocation in aspirin-sensitive subjects.
Topics: Administration, Oral; Adult; Airway Obstruction; Aspirin; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Free Radical Scavengers; Humans; Male; Middle Aged; Salicylates; Salicylic Acid; Sodium Salicylate | 1994 |
Plasma salicylate concentrations in immature dogs following aspirin administration: comparison with adult dogs.
Topics: Administration, Oral; Aging; Animals; Aspirin; Dogs; Female; Fluorescence Polarization Immunoassay; Half-Life; Injections, Intravenous; Male; Salicylates; Salicylic Acid | 1993 |
Aspirin and bismuth subsalicylate.
Topics: Aspirin; Bismuth; Child; Humans; Organometallic Compounds; Salicylates; Stomach Diseases | 1993 |
A clinical trial of a slow-release formulation of acetylsalicylic acid in patients at risk for preeclampsia.
Topics: Adult; Aspirin; Delayed-Action Preparations; Female; Fetal Blood; Humans; Indicators and Reagents; Infant, Newborn; Maternal-Fetal Exchange; Pre-Eclampsia; Pregnancy; Risk; Salicylates; Salicylic Acid; Thromboxane A2 | 1993 |
Transdermal modification of platelet function. A dermal aspirin preparation selectively inhibits platelet cyclooxygenase and preserves prostacyclin biosynthesis.
Topics: Administration, Cutaneous; Adult; Aspirin; Blood Platelets; Bradykinin; Cyclooxygenase Inhibitors; Epoprostenol; Female; Humans; Male; Middle Aged; Salicylates; Salicylic Acid; Thromboxane B2 | 1993 |
[Analgesics; the use of aspirin in dogs; effects of tablet type and food intake on plasma salicylate level].
Topics: Animals; Aspirin; Dog Diseases; Dogs; Food; Pain; Salicylates; Tablets; Time Factors | 1993 |
Transport of aspirin and its metabolites through human erythrocyte membrane.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Aspirin; Chemical Phenomena; Chemistry, Physical; Culture Media; Cytosol; Erythrocyte Membrane; Gentisates; Hippurates; Humans; Hydrolysis; Hydroxybenzoates; In Vitro Techniques; Salicylates; Salicylic Acid | 1993 |
Effect of aspirin on conformation and dynamics of membrane proteins in platelets and erythrocytes.
Topics: Anilino Naphthalenesulfonates; Aspirin; Blood Platelets; Cell Membrane; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Humans; Membrane Proteins; Protein Conformation; Salicylates; Salicylic Acid; Spin Labels; Tryptophan | 1993 |
Temporomandibular joint synovial fluid analysis.
Topics: Adolescent; Adult; Aspirin; Biopsy, Needle; Chromatography, High Pressure Liquid; Female; Hemoglobins; Humans; Male; Middle Aged; Salicylates; Sodium Chloride; Synovial Fluid; Temporomandibular Joint | 1993 |
Synthesis and some properties of two salsalate derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Antitussive Agents; Aspirin; Chromatography, Thin Layer; Edema; Expectorants; Guaiacol; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mice; Rats; Rats, Sprague-Dawley; Rats, Wistar; Salicylates; Spectrophotometry, Ultraviolet | 1993 |
Platelet adhesivity to subendothelium is influenced by polymorphonuclear leukocytes: studies with aspirin and salicylate.
Topics: 6-Ketoprostaglandin F1 alpha; Alprostadil; Animals; Aspirin; Blood Platelets; Cell Communication; Cyclooxygenase Inhibitors; Endothelium, Vascular; Humans; Lipoxygenase Inhibitors; Neutrophils; Platelet Adhesiveness; Rabbits; Salicylates; Salicylic Acid; Thromboxane B2 | 1993 |
Griseofulvin significantly decreases serum salicylate concentrations.
Topics: Aspirin; Child; Griseofulvin; Humans; Male; Rheumatic Heart Disease; Salicylates; Salicylic Acid; Tinea Capitis | 1993 |
Reinduction of the hypnotic effects of thiopental with NSAIDs by decreasing thiopental plasma protein binding in humans.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Proteins; Female; Humans; Hypnotics and Sedatives; Ibuprofen; In Vitro Techniques; Longitudinal Studies; Middle Aged; Naproxen; Protein Binding; Salicylates; Salicylic Acid; Sleep; Temperature; Thiopental | 1993 |
Liposome capillary electrophoresis for analysis of interactions between lipid bilayers and solutes.
Topics: Amino Acid Sequence; Aspirin; Electrophoresis, Capillary; Lipid Bilayers; Liposomes; Molecular Sequence Data; Molecular Structure; Peptides; Pharmaceutical Preparations; Salicylates; Salicylic Acid; Sulfasalazine; Thermodynamics; Warfarin | 1995 |
Salicylates and dicoumarol revisited--anything new under the sun?
Topics: Animals; Anticoagulants; Aspirin; Dicumarol; Europe; Female; History, 20th Century; Humans; Information Services; Male; Salicylates; United States | 1995 |
[The effect of salicylates on the toxicity of GABAlytics for mice].
Topics: Animals; Aspirin; Bicuculline; Drug Interactions; GABA Antagonists; Male; Mice; Picrotoxin; Protein Synthesis Inhibitors; Receptors, GABA-A; Salicylates; Salicylic Acid; Serum Albumin | 1995 |
Modification by analgesics of the susceptibility to antibiotics in Serratia marcescens.
Topics: Acetaminophen; Analgesics; Anti-Bacterial Agents; Aspirin; Bacterial Outer Membrane Proteins; beta-Lactamases; Cell Membrane Permeability; Drug Interactions; Drug Resistance, Microbial; Humans; In Vitro Techniques; Salicylates; Salicylic Acid; Serratia marcescens | 1995 |
Metabolic fate of the new antithrombotic agent aspalatone in rats. In vivo and in vitro study.
Topics: Animals; Aspirin; Biotransformation; Chromatography, High Pressure Liquid; Dealkylation; Esterases; Fibrinolytic Agents; Humans; In Vitro Techniques; Male; Platelet Aggregation Inhibitors; Prodrugs; Rats; Rats, Sprague-Dawley; Salicylates; Spectrophotometry, Ultraviolet | 1995 |
Maternal reproductive effects of oral salicylic acid in Sprague-Dawley rats.
Topics: Administration, Oral; Animals; Aspirin; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Female; Fetus; Labor, Obstetric; Male; No-Observed-Adverse-Effect Level; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Structure-Activity Relationship | 1996 |
Salicylate or aspirin inhibits the induction of the inducible nitric oxide synthase in rat cardiac fibroblasts.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Enzyme Induction; Fibroblasts; Interleukin-1; Myocardium; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; RNA, Messenger; Salicylates; Salicylic Acid; Tumor Necrosis Factor-alpha | 1996 |
Systemic inflammatory response syndrome caused by chronic salicylate intoxication.
Topics: Acid-Base Imbalance; Adult; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Disseminated Intravascular Coagulation; Female; Fever; Humans; Hypotension; Male; Middle Aged; Pulmonary Edema; Salicylates; Salicylic Acid; Systemic Inflammatory Response Syndrome | 1996 |
[Prescription of platelet antiaggregants in secondary prevention of ischemic heart disease].
Topics: Age Factors; Aged; Aged, 80 and over; Aspirin; Dipyridamole; Drug Prescriptions; Family Practice; Female; Humans; Male; Medical Audit; Medicine; Myocardial Ischemia; Platelet Aggregation Inhibitors; Prevalence; Primary Health Care; Salicylates; Spain; Specialization; Ticlopidine; Urban Population | 1996 |
The pharmacokinetics of salicylate in dairy cattle are not altered by simultaneous intravenous ceftiofur sodium and DL-lysine-acetyl salicylate (aspirin).
Topics: Animals; Aspirin; Cattle; Cephalosporins; Chromatography, High Pressure Liquid; Cross-Over Studies; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Half-Life; Injections, Intravenous; Reference Standards; Salicylates; Salicylic Acid | 1996 |
Laser induced resonance energy transfer--a novel approach towards achieving high sensitivity in capillary electrophoresis. I. Clinical diagnostic application.
Topics: Aminosalicylic Acid; Aspirin; Benzoates; Chemistry, Clinical; Electrophoresis, Capillary; Energy Transfer; Gentisates; Hippurates; Humans; Hydroxybenzoates; Lasers; Linear Models; Salicylates; Sensitivity and Specificity | 1996 |
The disposition of aspirin and salicylic acid in the isolated perfused rat liver: the effect of normal and retrograde flow on availability and mean transit time.
Topics: Animals; Aspirin; Female; In Vitro Techniques; Liver; Perfusion; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Sucrose | 1996 |
The risk of severe salicylate poisoning following the ingestion of topical medicaments or aspirin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Female; Humans; Male; Middle Aged; Poisoning; Retrospective Studies; Salicylates; Suicide, Attempted; Time Factors | 1996 |
[Successful therapy of salicylate poisoning using glycine and activated charcoal].
Topics: Adult; Aspirin; Charcoal; Female; Glycine; Humans; Male; Poisoning; Salicylates; Suicide, Attempted; Treatment Outcome | 1996 |
Aspirin related gastrointestinal bleeders have an exaggerated bleeding time response due to aspirin use.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Blood Coagulation; Factor VIII; Female; Gastrointestinal Hemorrhage; Hematocrit; Humans; Male; Middle Aged; Regression Analysis; Risk Factors; Salicylates; Salicylic Acid; Smoking; von Willebrand Factor | 1996 |
A highly sensitive HPLC method for the simultaneous determination of acetylsalicylic, salicylic and salicyluric acids in biologic fluids: pharmacokinetic, metabolic and monitoring implications.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromatography, High Pressure Liquid; Female; Hippurates; Humans; Male; Salicylates; Salicylic Acid | 1996 |
Acetylsalicylic acid is unlikely to beneficially interfere with radiation-induced vasculopathy.
Topics: Aspirin; Coronary Disease; Epoprostenol; Humans; Platelet Aggregation Inhibitors; Radiotherapy; Salicylates; Thromboxane A2 | 1997 |
Fluorimetric determination of tissue distribution and differences between the activity of aspirin esterases I and II in mice and rats.
Topics: Adrenal Glands; Animals; Aspirin; Brain; Carboxylic Ester Hydrolases; In Vitro Techniques; Isoenzymes; Kidney; Liver; Male; Mice; Organ Specificity; Rats; Rats, Wistar; Salicylates; Salicylic Acid; Species Specificity; Spectrometry, Fluorescence | 1997 |
Salicylate levels in rat stomach tissues after administration of aspalatone and acetylsalicylic acid in relation to their ulcerogenicity.
Topics: Animals; Aspirin; Gastric Mucosa; Male; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Salicylates; Stomach Ulcer | 1997 |
Comparative cytotoxicity of 5-aminosalicylic acid (mesalazine) and related compounds in different cell lines.
Topics: Aminosalicylic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Dogs; Glutathione; Humans; Kidney Tubules; Mesalamine; Neutral Red; Rats; Salicylates; Salicylic Acid; Structure-Activity Relationship; Swine; Tumor Cells, Cultured | 1997 |
Euglena gracilis as an eukaryotic test organism for detecting mutagens and antimutagens.
Topics: 4-Aminobenzoic Acid; Aminosalicylic Acid; Animals; Antimutagenic Agents; Aspirin; Chloroplasts; Euglena gracilis; Eukaryotic Cells; Methylnitronitrosoguanidine; Methylnitrosourea; Mutagenicity Tests; Mutagens; Mutation; ortho-Aminobenzoates; Pigmentation; Salicylates; Salicylic Acid; Sodium Salicylate | 1997 |
Helicobacter pylori and gastric adaptation to repeated aspirin administration in humans.
Topics: Adaptation, Physiological; Adult; Aspirin; DNA; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Gastroscopy; Helicobacter Infections; Helicobacter pylori; Humans; Male; Salicylates | 1997 |
Effect of aspirin and salicylate on LDL oxidation in vitro.
Topics: Aspirin; Humans; Kinetics; Lipoproteins, LDL; Salicylates; Salicylic Acid; Ultraviolet Rays | 1997 |
Direct assay and shelf-life monitoring of aspirin tablets using Raman spectroscopy.
Topics: Anti-Inflammatory Agents; Aspirin; Chromatography, High Pressure Liquid; Drug Storage; Reproducibility of Results; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Tablets | 1997 |
Determination of aspirin and salicylic acid in human plasma by column-switching liquid chromatography using on-line solid-phase extraction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Specimen Collection; Chromatography, High Pressure Liquid; Humans; Salicylates; Salicylic Acid | 1998 |
Determination of acetylsalicylic acid and salicylic acid in skin and plasma by high-performance liquid chromatography.
Topics: Administration, Oral; Administration, Topical; Area Under Curve; Aspirin; Chromatography, High Pressure Liquid; Epidermis; Humans; Reference Values; Reproducibility of Results; Salicylates; Salicylic Acid; Sensitivity and Specificity; Skin | 1998 |
Protein binding of aspirin and salicylate measured by in vivo ultrafiltration.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Proteins; Female; Half-Life; Humans; Male; Middle Aged; Protein Binding; Reference Values; Salicylates; Salicylic Acid; Ultrafiltration | 1998 |
Comparison of in vitro effects of triflusal and acetysalicylic acid on nitric oxide synthesis by human neutrophils.
Topics: Aspirin; Cyclic GMP; Cyclooxygenase Inhibitors; Humans; Neutrophils; Nitric Oxide; Platelet Aggregation Inhibitors; Salicylates | 1998 |
Continuous release of vasodilator prostanoids contributes to regulation of resting forearm blood flow in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Adult; Aspirin; Dose-Response Relationship, Drug; Female; Forearm; Humans; Male; Nitroprusside; Norepinephrine; Oxygen Consumption; Prostaglandins; Regional Blood Flow; Rest; Salicylates; Salicylic Acid; Time Factors; Vasodilation | 1998 |
Determination of aspirin and salicylic acid in transdermal perfusates.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calibration; Chromatography, High Pressure Liquid; Indicators and Reagents; Mice; Reference Standards; Reproducibility of Results; Salicylates; Salicylic Acid; Skin | 1998 |
Aspirin and salicylate induce apoptosis and activation of caspases in B-cell chronic lymphocytic leukemia cells.
Topics: Aged; Amino Acid Chloromethyl Ketones; Annexins; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; B-Lymphocytes; Cell Survival; Cyclooxygenase Inhibitors; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Activation; Female; Humans; Indomethacin; Ketorolac; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Proteins; Nitrobenzenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Salicylates; Salicylic Acid; Sulfonamides; Tolmetin; Tumor Cells, Cultured | 1998 |
A new salicylate ISFET for the determination of salicylic and acetylsalicylic acid in drugs.
Topics: Aspirin; Ion-Selective Electrodes; Membranes, Artificial; Ointments; Polyvinyl Chloride; Potentiometry; Salicylates; Salicylic Acid; Tablets; Transistors, Electronic | 1995 |
Reye's syndrome and salicylate use, by Karen M. Starko, MD, et al, Pediatrics, 1980;66:859-864; and National patterns of aspirin use and Reye syndrome reporting, United States, 1980 to 1985, by Janet B. Arrowsmith et al, Pediatrics, 1987;79:858-863.
Topics: Aspirin; Child; History, 20th Century; Humans; Reye Syndrome; Salicylates | 1998 |
Effect of cross-linked hemoglobin transfusion on endothelial-dependent dilation in cat pial arterioles.
Topics: Acetylcholine; Animals; Arterioles; Aspirin; Cats; Cross-Linking Reagents; Decanoic Acids; Endothelium, Vascular; Hemoglobins; Humans; Male; Molsidomine; Nitric Oxide Donors; Nitroarginine; Perfusion; Pia Mater; Salicylates; Serum Albumin; Vasodilation | 1998 |
Butyrylcholinesterase-catalysed hydrolysis of aspirin, a negatively charged ester, and aspirin-related neutral esters.
Topics: Acetylation; Aspirin; Binding Sites; Butyrylcholinesterase; Calcium; Enzyme Inhibitors; Esters; Humans; Hydrolysis; Kinetics; Magnesium; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Salicylates; Static Electricity | 1998 |
Aspirin and salicylate protect against MPTP-induced dopamine depletion in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aspirin; Body Temperature; Corpus Striatum; Cyclooxygenase Inhibitors; Dexamethasone; Dopamine; Hydroxybenzoates; Hydroxyl Radical; Lysine; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; MPTP Poisoning; Salicylates; Salicylic Acid; Serotonin; Synaptosomes | 1998 |
[When salicylates do not help. Practice in recurrent TIA (Transient Ischemic Attack) varies at Swedish hospitals].
Topics: Aged; Anticoagulants; Aspirin; Drug Therapy, Combination; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Platelet Aggregation Inhibitors; Practice Patterns, Physicians'; Recurrence; Salicylates; Surveys and Questionnaires; Sweden | 1998 |
[Intracerebral hemorrhage and treatment with platelet aggregation inhibitors: study of 21 cases].
Topics: Aged; Aged, 80 and over; Aspirin; Cerebral Hemorrhage; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Prognosis; Retrospective Studies; Risk Factors; Salicylates | 1998 |
Gender differences in the activities of aspirin-esterases in rat tissues.
Topics: Adrenal Glands; Animals; Aspirin; Brain; Carboxylic Ester Hydrolases; Estrus; Female; Kidney; Liver; Male; Rats; Rats, Wistar; Salicylates; Sex Differentiation; Sex Factors | 1998 |
Induction of apoptosis by salicylates in B-cell chronic lymphocytic leukemiak.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cryopreservation; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Count; Mitochondria; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Neoplastic Stem Cells; Salicylates | 1999 |
Beneficial effects of lysine acetylsalicylate, a soluble salt of aspirin, on motor performance in a transgenic model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Weight; Brain; Humans; Lysine; Male; Mice; Mice, Transgenic; Motor Activity; Muscle, Skeletal; Mutation; Postural Balance; Reflex; Salicylates; Solubility; Superoxide Dismutase | 1999 |
Inhibition of cyclooxygenase-2 expression by 4-trifluoromethyl derivatives of salicylate, triflusal, and its deacetylated metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Inflammation; Isoenzymes; Leukocytes, Mononuclear; Lipopolysaccharides; Male; Membrane Proteins; NF-kappa B; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Salicylates | 1999 |
Synthesis of [11C]salicylic acid and related compounds and their biodistribution in mice.
Topics: Acetylation; Animals; Anti-Infective Agents; Aspirin; Brain; Carbon Radioisotopes; Hydroxybenzoate Ethers; Isotope Labeling; Male; Mice; Radiopharmaceuticals; Salicylates; Salicylic Acid; Tissue Distribution | 1999 |
4-trifluoromethyl derivatives of salicylate, triflusal and its main metabolite 2-hydroxy-4-trifluoromethylbenzoic acid, are potent inhibitors of nuclear factor kappaB activation.
Topics: Animals; Aspirin; Cell Line; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Macrophages, Peritoneal; NF-kappa B; Nitric Oxide; Platelet Aggregation Inhibitors; Rats; RNA, Messenger; Salicylates; Thrombin; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 1999 |
Gastrointestinal safety of nitric oxide-derived aspirin is related to inhibition of ICE-like cysteine proteases in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase Inhibitors; Caspases; Cyclic GMP; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Gastric Mucosa; Humans; In Situ Nick-End Labeling; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Rats; Salicylates; Time Factors; Tumor Necrosis Factor-alpha; U937 Cells | 1999 |
Salicylates and sulfasalazine, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NFkappaB.
Topics: Adenosine Deaminase; Animals; Aspirin; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Female; Glucocorticoids; Inflammation; Isoenzymes; Leukocytes; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; NF-kappa B; NF-kappa B p50 Subunit; Prostaglandin-Endoperoxide Synthases; Protein Precursors; Purinergic P1 Receptor Antagonists; Salicylates; Sodium Salicylate; Sulfasalazine; Theobromine | 1999 |
Bioreductively-activated prodrugs for targeting hypoxic tissues: elimination of aspirin from 2-nitroimidazole derivatives.
Topics: Animals; Aspirin; Bromides; Cell Hypoxia; Humans; Nitroimidazoles; Prodrugs; Salicylates; Time Factors | 1999 |
Ex vivo assay to determine the cyclooxygenase selectivity of non-steroidal anti-inflammatory drugs.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Blood Pressure; Carcinoma; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indans; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salicylates; Substrate Specificity; Sulfonamides; Sulindac; Thromboxane B2; Tumor Cells, Cultured | 1999 |
Effects of salicylate and related compounds on fusidic acid MICs in Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Aspirin; Bacteriophage Typing; Benzoates; DNA, Bacterial; Drug Resistance, Microbial; Electrophoresis, Gel, Pulsed-Field; Fusidic Acid; Humans; Ibuprofen; Microbial Sensitivity Tests; Salicylates; Staphylococcus aureus | 1999 |
Salicylate-enhanced activation of transcription factors induced by interferon-gamma.
Topics: Animals; Aspirin; Cells, Cultured; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Interferon Regulatory Factor-1; Interferon-gamma; Mice; Phosphoproteins; RNA, Messenger; Salicylates; STAT1 Transcription Factor; Trans-Activators; Transcription Factors; Transcriptional Activation | 1999 |
The effect of aspirin administration and parity on plasma salicylate concentrations and postpartum reproductive parameters in Brahman cows.
Topics: Animals; Aspirin; Body Weight; Cattle; Dinoprost; Estrus; Female; Parity; Postpartum Period; Pregnancy; Pregnancy, Animal; Progesterone; Salicylates; Sex Factors | 1999 |
Effects of salicylic acid derivatives on red blood cell membranes.
Topics: Aspirin; Cell Membrane; Cell Size; Dose-Response Relationship, Drug; Erythrocyte Membrane; Humans; In Vitro Techniques; Photometry; Salicylamides; Salicylates; Sodium Salicylate; Time Factors | 1999 |
Effects of salicylates and aminoglycosides on spontaneous otoacoustic emissions in the Tokay gecko.
Topics: Animals; Anti-Bacterial Agents; Aspirin; Cochlea; Gentamicins; Kanamycin; Lizards; Otoacoustic Emissions, Spontaneous; Salicylates; Sodium Salicylate | 2000 |
May aspirin be replaced in the treatment of myocardial infarction?
Topics: Aspirin; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Salicylates | 2000 |
Acetaminophen inhibits iNOS gene expression in RAW 264.7 macrophages: differential regulation of NF-kappaB by acetaminophen and salicylates.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Catalysis; Cell Extracts; Cell Line; DNA; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Promoter Regions, Genetic; Protein Binding; Protein Biosynthesis; RNA Stability; RNA, Messenger; Salicylates; Sodium Salicylate | 2000 |
Salicylate metabolites inhibit cyclooxygenase-2-dependent prostaglandin E(2) synthesis in murine macrophages.
Topics: Acyl Coenzyme A; Animals; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gentisates; Hydroxybenzoates; Inflammation; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salicylates; Sodium Salicylate | 2000 |
Effect of experimental spinal cord injury on salicylate bioavailability after oral aspirin administration.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biological Availability; Female; Rats; Rats, Sprague-Dawley; Salicylates; Spinal Cord Injuries | 1999 |
Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen.
Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Division; Cell Line; Cyclin A; Cyclin D1; Epidermal Growth Factor; Gene Expression Regulation; Genes, myc; Humans; Indomethacin; Insulin-Like Growth Factor I; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myc; Ribosomal Protein S6 Kinases; Salicylates; Tetradecanoylphorbol Acetate | 2000 |
Choroidal neovascular membrane presenting as a complication of pre-eclampsia in a patient with the antiphospholipid syndrome.
Topics: Adult; Antiphospholipid Syndrome; Aspirin; Choroidal Neovascularization; Female; Fluorescein Angiography; Humans; Pre-Eclampsia; Pregnancy; Salicylates; Treatment Outcome; Visual Acuity | 2000 |
Aspirin and salicylate: An old remedy with a new twist.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; CCAAT-Enhancer-Binding Protein-beta; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Humans; Isoenzymes; Membrane Proteins; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Salicylates | 2000 |
[Prevention of thromboembolic disease in patients with heart disease].
Topics: Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Cross-Sectional Studies; Dipyridamole; Female; Heart Diseases; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Risk Factors; Salicylates; Sex Factors; Thromboembolism; Ticlopidine | 2000 |
Acetylsalicylic acid and other salicylates in relation to Stevens-Johnson syndrome and toxic epidermal necrolysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Humans; Multivariate Analysis; Salicylates; Stevens-Johnson Syndrome | 2001 |
Aspirin: aspiring for a century (1899 to 1999) and the willow bark is still batting!
Topics: Aspirin; Germany; History, 19th Century; History, 20th Century; Humans; India; Pharmacology; Plant Extracts; Salicylates; Trees | 1998 |
Low gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in rats with cirrhosis and arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Blood Flow Velocity; Gastric Acid; Gastric Mucosa; Hydrochloric Acid; Liver Cirrhosis; Male; Membrane Potentials; Nitric Oxide Donors; Nitro Compounds; Rats; Rats, Sprague-Dawley; Salicylates; Stomach Ulcer | 2001 |
Effects of the nuclear factor-kappaB inhibitors 2-hydroxy-4-trifluoromethylbenzoic acid and aspirin on micturition in rats with normal and inflamed bladder.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Cystitis; Female; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Salicylates; Urination; Urodynamics | 2001 |
Absence of nuclear factor kappaB inhibition by NSAIDs in hepatocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Fetus; HeLa Cells; Hepatocytes; Humans; Inflammation Mediators; Isoenzymes; Lipopolysaccharides; Membrane Proteins; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salicylates; Tumor Cells, Cultured | 2002 |
Nitric oxide, anti-inflammatory drugs on renal prostaglandins and cyclooxygenase-2.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Kidney; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins F; Pyrazoles; Rabbits; Salicylates; Sulfonamides; Thromboxane B2 | 2002 |
Chromium(III) porphyrin as a selective ionophore in a salicylate-selective membrane electrode.
Topics: Aspirin; Chromium Compounds; Humans; Ion-Selective Electrodes; Ionophores; Pharmaceutical Preparations; Porphyrins; Salicylates | 2002 |
Transition metal acetylsalicylates and their anti-inflammatory activity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cobalt; Copper; Metals; Molecular Conformation; Molecular Structure; Nickel; Salicylates; Structure-Activity Relationship; Zinc | 2002 |
[Neuroprotection by aspirin in cerebrovascular pathology].
Topics: Adenosine Triphosphate; Algorithms; Amino Acid Transport System X-AG; Animals; Aspirin; Brain Ischemia; Cell Death; Cerebrovascular Disorders; Clinical Trials as Topic; Disease Models, Animal; Glucose; Glutamic Acid; Humans; Indomethacin; Mitochondria; Neuroprotective Agents; Oxygen; Salicylates | 2002 |
Aspirin inhibits the growth of Helicobacter pylori and enhances its susceptibility to antimicrobial agents.
Topics: Amoxicillin; Anti-Bacterial Agents; Aspirin; Clarithromycin; Dose-Response Relationship, Drug; Drug Synergism; Helicobacter pylori; Metronidazole; Microbial Sensitivity Tests; Salicylates | 2003 |
Can aspirin ever be surpassed for stroke prevention?
Topics: Aspirin; Clinical Trials as Topic; Drug Therapy, Combination; Fibrinolytic Agents; Forecasting; Humans; Platelet Aggregation Inhibitors; Salicylates; Stroke | 2003 |
Labeling for oral and rectal over-the-counter drug products containing aspirin and nonaspirin salicylates; Reye's Syndrome warning. Final rule.
Topics: Administration, Oral; Administration, Rectal; Adolescent; Antidiarrheals; Aspirin; Child; Contraindications; Drug Labeling; Humans; Legislation, Drug; Nonprescription Drugs; Reye Syndrome; Salicylates; United States; United States Food and Drug Administration | 2003 |
Effects of aspirin and/or salicylate on hydrolysis and glucuronidation of indomethacin in rat erythrocytes and hepatocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzbromarone; Carboxylesterase; Chromatography, High Pressure Liquid; Drug Interactions; Erythrocytes; Glucuronides; Hepatocytes; Hydrolysis; In Vitro Techniques; Indomethacin; Male; Microsomes, Liver; Rats; Rats, Wistar; Salicylates | 2003 |
Photosynthetic responses of corn and soybean to foliar application of salicylates.
Topics: Aspirin; Chlorophyll; Gases; Gentisates; Glycine max; Hydroxybenzoates; Molecular Structure; Phenols; Photosynthesis; Plant Leaves; Salicylates; Zea mays | 2003 |
[Separation of salicylic acid drugs by aqueous and nonaqueous capillary electrophoresis with conductance detector].
Topics: Aspirin; Benzenesulfonates; Electrophoresis, Capillary; Ethanol; Salicylates; Salicylic Acid; Sensitivity and Specificity; Tablets; Water | 2003 |
Dietary salicylates.
Topics: Aspirin; Cyclooxygenase Inhibitors; Diet; Diet, Vegetarian; Fruit; Humans; Micronutrients; Salicylates; Vegetables | 2003 |
Urinary excretion of salicyluric and salicylic acids by non-vegetarians, vegetarians, and patients taking low dose aspirin.
Topics: Adolescent; Adult; Aged; Aspirin; Biological Availability; Cyclooxygenase Inhibitors; Diet, Vegetarian; Drug Administration Schedule; Female; Hippurates; Humans; Male; Middle Aged; Salicylates; Statistics, Nonparametric | 2003 |
Salicylate intoxication.
Topics: Aspirin; Humans; Salicylates | 1952 |
[Modification of the sedimentation rate by the addition in vitro, of so-called anti-inflammatory drugs].
Topics: Adrenocorticotropic Hormone; Aminosalicylic Acid; Analgesics; Anti-Inflammatory Agents; Aspirin; Blood Sedimentation; Cortisone; Hematologic Tests; Humans; In Vitro Techniques; Salicylates | 1952 |
[Vestibular chronaximetry as a measure of the posttoxic impregnation time of the organism with acetylsalicylic acid, alcohol benzene and lead].
Topics: Aspirin; Benzene; Ethanol; Humans; Lead Poisoning; Salicylates; Vestibular Nerve; Vestibule, Labyrinth | 1952 |
Investigation of some complexes formed in solution by caffeine. III. Interactions between caffeine and aspirin, p-hydroxybenzoic acid, m-hydroxybenzoic acid, salicylic acid, salicylate ion, and butyl paraben.
Topics: Aspirin; Benzoates; Caffeine; Hydroxybenzoates; Parabens; Pharmaceutical Solutions; Salicylates; Salicylic Acid; Solutions | 1953 |
Some recent advances in the pharmacology of salicylates.
Topics: Aspirin; Salicylates; Salicylic Acid | 1953 |
Aspirin poisoning.
Topics: Aspirin; Child; Humans; Infant; Poisoning; Salicylates | 1953 |
Toxicity of salicylamide; effect of combining salicylamide with sodium salicylate and acetyl-salicylic acid on the lethality of these substances for white mouse.
Topics: Animals; Anthelmintics; Aspirin; Mice; Salicylamides; Salicylates; Sodium Salicylate | 1952 |
The effect of aspirin upon the glycosuria of partially depancreatized rats in the presence and absence of the adrenal glands.
Topics: Adrenal Glands; Animals; Aspirin; Glycosuria; Rats; Salicylates | 1953 |
Hemorrhage due to acetylsalicylic acid; report of a case.
Topics: Aspirin; Hemorrhage; Humans; Liver; Salicylates | 1953 |
Aspirin poisoning in children.
Topics: Aspirin; Humans; Salicylates | 1953 |
[Iromin; a new salicylate preparation].
Topics: Aspirin; Humans; Salicylates | 1953 |
[Aspirin poisoning in children].
Topics: Aspirin; Humans; Salicylates | 1953 |
[The analgesic potency of acetylsalicylic acid and salicylamide; algesiametric measurements and their results in practice].
Topics: Analgesics; Aspirin; Salicylamides; Salicylates | 1953 |
[Action of the sodium salts of disalicylic, succinyldisalicylic, sulfosalicylic and acetylsalicylic acids on choleresis and diuresis in the dog under chloralose anesthesia].
Topics: Anesthesia; Anesthesiology; Animals; Aspirin; Bile; Chloralose; Cholagogues and Choleretics; Diuresis; Dogs; Salicylates; Salts; Sodium | 1953 |
Succinate-salicylate in treatment of arthritic disorders.
Topics: Arthritis; Aspirin; Humans; Salicylates; Succinates; Succinic Acid | 1954 |
Studies on 17-hydroxycorticosteroids. III. Blood levels in salicylate intoxication.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Adrenal Cortex Hormones; Aspirin; Blood; Humans; Poisoning; Salicylates | 1954 |
[Medication which induces the formation of hormones: salicylate therapy].
Topics: Adrenal Cortex; Aminosalicylic Acid; Aspirin; Body Fluids; Salicylates; Steroids; Urine | 1953 |
Spectrophotometric determination of acetylsalicylic and salicylic acids.
Topics: Aspirin; Salicylates; Salicylic Acid; Spectrophotometry | 1954 |
Salicylates and the plasma level of adrenal steroids.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Arthritis; Arthritis, Rheumatoid; Aspirin; Humans; Rheumatic Fever; Salicylates | 1954 |
Salicylate intoxication in infants and children.
Topics: Aspirin; Child; Humans; Infant; Poisoning; Salicylates | 1954 |
[Important new drugs].
Topics: Aspirin; Furans; Gentisates; Humans; Salicylates | 1954 |
[Enzymatic hydrolysis of salicylic acid esters by body fluids and organs of Helix pomatia L. II. Orthoacetylcresotic, salicylosalicylic, succinyldisalicylic and diisopropylacetylsalicylic acids].
Topics: Animals; Aspirin; Body Fluids; Esters; Hydrolysis; Salicylates; Snails | 1954 |
Salicylate intoxication.
Topics: Aspirin; Child; Humans; Infant; Poisoning; Salicylates | 1954 |
Salicylate overdosage and intoxication in infants and young children.
Topics: Aspirin; Child; Drug Overdose; Humans; Infant; Poisoning; Salicylates | 1954 |
Specific therapy for salicylism.
Topics: Aspirin; Humans; Kidneys, Artificial; Salicylates | 1955 |
Salicylate therapy of recurrent calcium urolithiasis.
Topics: Aspirin; Calcium; Calculi; Humans; Salicylates; Urinary Calculi; Urinary Tract | 1955 |
Studies in urolithiasis. IV. Urinary glucuronosides and calcium phosphate.
Topics: Aspirin; Biliary Tract; Biliary Tract Diseases; Calcium Phosphates; Calculi; Humans; Kidney; Kidney Calculi; Salicylates; Urolithiasis | 1955 |
Salicylamide and acetylsalicylic acid in recurrent urolithiasis.
Topics: Aspirin; Calculi; Humans; Salicylamides; Salicylates; Urinary Calculi; Urinary Tract | 1956 |
A colorimetric comparison of plasma-salicylate levels following the oral administration of certain salicylates to rabbits.
Topics: Administration, Oral; Animals; Aspirin; Blood; Colorimetry; Humans; Lagomorpha; Rabbits; Salicylates | 1956 |
Treatment of rheumatoid arthritis and osteoarthritis with succinate-salicylate.
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Humans; Osteoarthritis; Salicylates; Succinates; Succinic Acid | 1955 |
[Hydrolysis and in vivo elimination of various salicylate derivatives: salicylsalicylic acid and succinyldisalicylic acid; determination of hemicresis and protorrhea].
Topics: Aspirin; Humans; Hydrolysis; Salicylates; Urine | 1955 |
Hemorrhagic diathesis with increased capillary fragility caused by salicylate therapy.
Topics: Aspirin; Capillaries; Capillary Fragility; Hemorrhage; Hemorrhagic Disorders; Humans; Salicylates; Vascular Diseases | 1956 |
[Causes of bleeding in acetylsalicylic acid poisoning].
Topics: Aspirin; Hemorrhage; Humans; Salicylates | 1956 |
The effect of salicylates and adrenocortical hormones on C-reactive protein.
Topics: Adrenal Cortex Hormones; Aspirin; Blood Proteins; C-Reactive Protein; Salicylates | 1957 |
[Metabolic studies on drugs. I. Synthesis of radiocarbon labelled salicylic acid (carboxy-C14), acetetylsalicylic acid (carboxy-C14 & acetyl-1-C14), salicyluric acid (carbamyl-C14), and gentisic acid (carboxy-C14)].
Topics: Aspirin; Gentisates; Hippurates; Salicylates; Uric Acid | 1957 |
[Metabolic studies on drugs. II. Metabolic products of salicylic, acetylsalicylic, gentisic, and salicyluric acids in rat urine].
Topics: Animals; Aspirin; Biochemical Phenomena; Gentisates; Hippurates; Rats; Salicylates; Salicylic Acid; Uric Acid | 1957 |
A corticosteroid-salicylate in general practice.
Topics: Adrenal Cortex Hormones; Antacids; Arthritis; Ascorbic Acid; Aspirin; General Practice; Humans; Prednisone; Rheumatic Diseases; Salicylates; Vitamins | 1957 |
Prednisone alone and in combination with salicylates and phenylbutazone in the treatment of rheumatoid arthritis.
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Humans; Phenylbutazone; Prednisone; Salicylates | 1957 |
ANALGESIC drugs. III. Non-narcotics. II. Pharmacologic action of the salicylates.
Topics: Analgesics; Aspirin; Humans; Narcotics; Salicylates | 1957 |
Salicylates and gastric hemorrhage. I. Occult bleeding.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Salicylates; Stomach; Stomach Diseases | 1957 |
Salicylates and gastric hemorrhage. II. Manifest bleeding.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Salicylates; Stomach; Stomach Diseases | 1957 |
[Aspirin poisoning and its therapy].
Topics: Aspirin; Salicylates | 1957 |
Acute renal failure in salicylate poisoning.
Topics: Acute Kidney Injury; Aspirin; Humans; Salicylates | 1958 |
[Acetylsalicylic acid, not a harmless drug; salicylate poisoning in children].
Topics: Aspirin; Child; Humans; Salicylates | 1958 |
Aspirin poisoning in children; a review of the literature.
Topics: Aspirin; Child; Humans; Salicylates | 1958 |
Salicylate intoxication in an adult.
Topics: Adult; Aspirin; Humans; Salicylates | 1958 |
[Acute hemorrhagic papillitis during subacute aspirin poisoning].
Topics: Aspirin; Eye Diseases; Hemorrhage; Humans; Papilledema; Salicylates | 1958 |
A study of the oxidative metabolism of acetylsalicylic, salicylic, and gentisic acid in fevered animals.
Topics: Animals; Aspirin; Fever; Gentisates; Salicylates; Salicylic Acid | 1958 |
Dinitrophenol and diabetes mellitus: a comparison with salicylate.
Topics: Aspirin; Diabetes Mellitus; Dinitrophenols; Humans; Nitrophenols; Salicylates | 1958 |
The relation of the thyroid to the calorigenic response to salicylate.
Topics: Aspirin; Energy Metabolism; Myxedema; Salicylates; Thyroid Gland | 1958 |
The prevention of acetylsalicylic acid poisonings.
Topics: Aspirin; Biomedical Research; Humans; Salicylates | 1958 |
Management of acute aspirin poisoning in children.
Topics: Aspirin; Child; Disease Management; Humans; Salicylates | 1958 |
The insulin equivalence of salicylate.
Topics: Aspirin; Diabetes Mellitus; Humans; Insulin; Salicylates | 1959 |
[Aspirin poisoning in children].
Topics: Aspirin; Humans; Salicylates | 1959 |
PETROLEUM distillates (furniture polish), aspirin, and other ingestions and suicidal attempts.
Topics: Aspirin; Child; Dermatitis, Toxicodendron; Eating; Humans; Infant; Interior Design and Furnishings; Petrolatum; Petroleum; Salicylates; Suicide, Attempted | 1959 |
Exchange transfusion for aspirin poisoning.
Topics: Aminosalicylic Acid; Aspirin; Blood Transfusion; Drug-Related Side Effects and Adverse Reactions; Exchange Transfusion, Whole Blood; Humans; Salicylates | 1959 |
Aspirin substitutes.
Topics: Aspirin; Gentisates; Salicylamides; Salicylates | 1961 |
Aspirin poisoning-C9H804.
Topics: Aspirin; Salicylates | 1960 |
The use of exchange transfusion in salicylate intoxication; report of 7 cases.
Topics: Aspirin; Blood Transfusion; Exchange Transfusion, Whole Blood; Humans; Salicylates | 1960 |
Changes in pain tolerance and other behavior produced by salicylates.
Topics: Aspirin; Humans; Ozone; Pain Threshold; Salicylates; Sodium Salicylate | 1961 |
The effect of salicylate on the serum lipids and lipoproteins in coronary artery disease.
Topics: Aspirin; Coronary Artery Disease; Coronary Disease; Humans; Lipids; Lipoproteins; Salicylates | 1959 |
[Proposals for the DAB 7. 6. Acetanilid, acetylsalicylic acid, salicylic acid, sodium salicylate].
Topics: Acetanilides; Aspirin; Salicylates; Salicylic Acid; Sodium Salicylate | 1959 |
Pulmonary oedema due to salicylate intoxication.
Topics: Aspirin; Humans; Pulmonary Edema; Salicylates | 1960 |
beta-Glucuronidase hydrolysis of urinary corticosteroid conjugates: the effect of salicylate glucuronoside as a competing substrate and the effect of enzyme inactivation.
Topics: Adrenal Cortex Hormones; Aspirin; Body Fluids; Glucuronidase; Glycoside Hydrolases; Humans; Hydrolysis; Salicylates | 1960 |
[Treatment of Crohn's disease with salicylate derivatives].
Topics: Aspirin; Crohn Disease; Humans; Ileitis; Prednisone; Salicylates | 1961 |
Relationship of plasma salicylate concentration to urinary salicylate excretion-rate.
Topics: Aspirin; Body Fluids; Humans; Salicylates | 1962 |
[Salicylate poisoning in children].
Topics: Aspirin; Child; Humans; Salicylates | 1963 |
Salicylate action and thyroidal autonomy in hyperthyroidism.
Topics: Aspirin; Humans; Hyperthyroidism; Salicylates; Thyroid Function Tests | 1963 |
[New considerations on the treatment of gastric disorders produced by salicylate].
Topics: Achlorhydria; Arthritis; Arthritis, Rheumatoid; Aspirin; Gastric Juice; Salicylates; Stomach Diseases | 1962 |
[On the mechanism of action of salicylic acid, acetylsalicylic acid and salicylamide].
Topics: Aspirin; Salicylamides; Salicylates; Salicylic Acid | 1963 |
Aspirin poisoning with two fatalities.
Topics: Aspirin; Humans; Salicylates | 1963 |
Aspirin poisoning.
Topics: Aspirin; Humans; Poisoning; Salicylates | 1963 |
Carbon tetrachloride, iron, and aspirin poisonings.
Topics: Aspirin; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Iron; Salicylates | 1963 |
A century of salicylates.
Topics: Aspirin; Humans; Salicylates | 1963 |
Topical action of salicylates in gastrointestinal erosion and hemorrhage.
Topics: Aspirin; Gastrointestinal Tract; Hemorrhage; Humans; Mouth; Mucous Membrane; Phenacetin; Salicylates; Stomach | 1963 |
Severe salicylism and acute pancreatitis.
Topics: Aspirin; Humans; Lactates; Pancreatitis; Salicylates | 1963 |
[Poisoning by aspirin and salicylates].
Topics: Aspirin; Humans; Salicylates | 1963 |
Use of a muscle relaxant salicylate combination in chronic rheumatic diseases.
Topics: Anti-Allergic Agents; Aspirin; Guaifenesin; Histamine H1 Antagonists; Humans; Rheumatic Diseases; Salicylates | 1963 |
The effects of oral salicylate on serum uric acid levels.
Topics: Aspirin; Female; Humans; Male; Salicylates; Uric Acid | 1963 |
Renal irritation caused by salicylates.
Topics: Aspirin; Humans; Kidney; Kidney Diseases; Kidney Tubules; Salicylates; Skin Diseases | 1963 |
[Contributions to evaluation of the substances inhibiting inflammation].
Topics: Aminopyrine; Aspirin; Inflammation; Phenylbutazone; Quinolines; Salicylates | 1963 |
[The treatment of acute rheumatic fever].
Topics: Adrenal Cortex Hormones; Aspirin; Rheumatic Fever; Salicylates | 1962 |
Salicylates and gastrointestinal bleeding. Acetylsalicylic acid and aspirin derivatives.
Topics: Aspirin; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Salicylates | 1962 |
[Pharmacological study of choline salicylate. Comparison with acetylsalicylic acid. I. Toxicity. Blood content after ingestion].
Topics: Aspirin; Choline; Drug Combinations; Humans; Research; Salicylates | 1963 |
[Pharmacological study of choline salicylate. Comparison with acetylsalicylic acid. II. Analgesic action, antipyretic actions].
Topics: Analgesics; Antipyretics; Aspirin; Choline; Drug Combinations; Humans; Salicylates | 1963 |
[On the absorption of acetylsalicylic acid and salicylates in association with N-isopropyl-2-methyl-2-propyl-1,3-propanediol dicarbamate (Carisoprodol)].
Topics: Aspirin; Carisoprodol; Humans; Propylene Glycol; Propylene Glycols; Salicylates | 1963 |
[DIGESTIVE HEMORRHAGE PRODUCED BY SALICYLATES].
Topics: Aspirin; Digestion; Gastrointestinal Hemorrhage; Hemorrhage; Salicylates; Toxicology | 1963 |
THE DETECTION OF HUMORAL ANTIBODIES DIRECTED AGAINST SALICYLATES IN HYPERSENSITIVE STATES.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anaphylaxis; Animals; Antibodies; Antibody Formation; Aspirin; Drug Hypersensitivity; Guinea Pigs; Hemagglutination; Hemagglutination Tests; Precipitin Tests; Rabbits; Research; Salicylates | 1963 |
GASTROINTESTINAL ABSORPTION OF ASPIRIN ANHYDRIDE.
Topics: Absorption; Anhydrides; Aspirin; Body Fluids; Gastrointestinal Absorption; Gastrointestinal Tract; Humans; Intestinal Absorption; Physiology; Salicylates; Urine | 1963 |
DEGENERATIVE JOINT DISEASES--DISCS AND OSTEOARTHRITIS. II. DIAGNOSIS AND MANAGEMENT OF OSTEOARTHRITIS.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Diagnosis, Differential; Humans; Osteoarthritis; Oxyphenbutazone; Phenacetin; Phenylbutazone; Physical Therapy Modalities; Salicylates | 1963 |
INFLAMMATORY POLYARTHRITIC DISEASE. IV. GOUT.
Topics: Arthritis; Aspirin; Chlorothiazide; Colchicine; Gout; Hydrochlorothiazide; Mecamylamine; Pempidine; Phenylbutazone; Probenecid; Pyrazoles; Salicylates | 1963 |
CHEMOTHERAPY OF ARTHRITIS INDUCED IN RATS BY MYCOBACTERIAL ADJUVANT.
Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Betamethasone; Chloroquine; Cortisone; Dexamethasone; Humans; Hydroxychloroquine; Male; Mycobacterium; Paramethasone; Phenylbutazone; Prednisolone; Rats; Research; Salicylates; Sodium Salicylate | 1963 |
A SIMPLIFIED URINE AND SERUM SCREENING TEST FOR SALICYLATE INTOXICATION.
Topics: Aspirin; Blood Chemical Analysis; Clinical Laboratory Techniques; Dogs; Hematologic Tests; Laboratories; Research; Salicylates; Toxicology; Urine | 1963 |
PULMONARY EDEMA DUE TO SALICYLATE INTOXICATION: REPORT OF A CASE.
Topics: Aspirin; Humans; Pulmonary Edema; Radiography, Thoracic; Salicylates; Toxicology | 1963 |
DRUG RELIEF OF PAIN.
Topics: Acetanilides; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Dextropropoxyphene; Narcotics; Opium; Pain; Phenacetin; Salicylates; Toxicology; Tranquilizing Agents | 1963 |
[CLINICAL CONTRIBUTION TO THE USE OF THE NEW ANALGESIC AND ANTIPYRETIC CALCIUM-ACETYL-SALICYLATE CARBAMIDE].
Topics: Analgesics; Antipyretics; Arthritis; Arthritis, Rheumatoid; Aspirin; Fibromyalgia; Humans; Neuritis; Salicylates; Urea | 1963 |
[2 CASES OF ASPIRIN POISONING DURING THE COURSE OF THERAPY WITH ACCEPTED DOSES].
Topics: Acid-Base Equilibrium; Aspirin; Child; Humans; Rheumatic Fever; Salicylates; Toxicology | 1963 |
[FATAL ASPIRIN POISONING IN CHILDHOOD].
Topics: Aspirin; Child; Diagnosis; Humans; Infant; Kidney; Kidneys, Artificial; Mortality; Propylene Glycols; Salicylates; Toxicology; Tromethamine | 1963 |
THE EFFECT OF SALICYLATES UPON THE STOMACHS OF DOGS.
Topics: Aspirin; Dogs; Gastric Mucosa; Gastritis; Gastroscopy; Pharmacology; Research; Salicylates; Sodium Salicylate; Toxicology | 1964 |
HEMORRHAGIC DIATHESIS DUE TO SALICYLATE-INDUCED HYPOPROTHROMBINEMIA.
Topics: Adrenocorticotropic Hormone; Aspirin; Blood Transfusion; Caffeine; Diphenhydramine; Hematoma; Hemorrhagic Disorders; Hypoprothrombinemias; Mouth; Phenacetin; Salicylates; Toxicology; Vitamin K 1 | 1964 |
DRUGS CONTAINING ASPIRIN.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Salicylates; Toxicology; United Kingdom; United States | 1964 |
[EVALUATION OF ENTERIC-COATED ASPIRIN IN CHRONIC RHEUMATOID ARTHRITIS].
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Carbohydrate Metabolism; Delayed-Action Preparations; Humans; Polysaccharides; Salicylates; Uracil Nucleotides | 1964 |
ANALGESICS FOR THE RELIEF OF PAIN. II. NONNARCOTIC ANALGESICS.
Topics: Acetanilides; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Dextropropoxyphene; Muscle Relaxants, Central; Pain; Pharmacology; Phenacetin; Phenylbutazone; Salicylamides; Salicylates; Toxicology | 1964 |
SCREENING TEST FOR HIGH SERUM SALICYLATE LEVELS.
Topics: Aspirin; Blood Chemical Analysis; Body Fluids; Coma; Indicators and Reagents; Salicylates; Toxicology; Urine | 1964 |
ACUTE SALICYLATE POISONING IN ADULTS.
Topics: Acute Kidney Injury; Aspirin; Blood Chemical Analysis; Bronchopneumonia; Coma; Diagnosis, Differential; Diuresis; Gastric Lavage; Heart Arrest; Heart Failure; Humans; Infusions, Parenteral; Kidney; Kidneys, Artificial; Phenacetin; Poisoning; Pulmonary Edema; Renal Insufficiency; Salicylates; Statistics as Topic; Toxicology | 1964 |
SIMULTANEOUS SALICYLATE CONCENTRATIONS IN SYNOVIAL FLUID AND PLASMA IN RHEUMATOID ARTHRITIS.
Topics: Arthritis; Arthritis, Rheumatoid; Ascorbic Acid; Aspirin; Blood Chemical Analysis; Humans; Knee; Plasma; Proteins; Salicylates; Serum Albumin; Synovial Fluid | 1964 |
TREATMENT OF SEVERE ASPIRIN POISONING WITHOUT DIALYSIS.
Topics: Acidosis; Alkalosis; Aspirin; Bicarbonates; Blood Chemical Analysis; Diuretics; Gastric Lavage; Humans; Infusions, Parenteral; Kidney Function Tests; Kidneys, Artificial; Mannitol; Poisoning; Potassium; Renal Dialysis; Salicylates; Sodium; Stomach; Toxicology; Urea; Urinary Catheterization; Urine | 1964 |
HYPOGLYCEMIA WITH SALICYLATE POISONING. A REPORT OF TWO CASES.
Topics: Aspirin; Child; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Infusions, Parenteral; Neurologic Manifestations; Pancreatic Diseases; Poisoning; Salicylates; Toxicology | 1964 |
SALICYLATE INTOXICATION IN CHILDREN--EXPERIENCE WITH PERITONEAL DIALYSIS AND ALKALINIZATION OF THE URINE.
Topics: Albumins; Aspirin; Bicarbonates; Blood; Blood Proteins; Calcium; Calcium, Dietary; Child; Chlorides; Dialysis; Hydrogen-Ion Concentration; Infant; Infusions, Parenteral; Osmosis; Peritoneal Dialysis; Potassium; Renal Dialysis; Salicylates; Sodium; Toxicology; Urine; Vitamin K | 1964 |
SERUM SALICYLATE LEVELS IN OSTEOARTHRITIS FOLLOWING ORAL ADMINISTRATION OF A PREPARATION CONTAINING SALICYLSALICYLIC ACID.
Topics: Administration, Oral; Aspirin; Blood; Blood Chemical Analysis; Drug Therapy; Geriatrics; Humans; Osteoarthritis; Salicylates; Salicylic Acid | 1964 |
AMINOACIDURIA INDUCED BY SALICYLATES.
Topics: Aspirin; Blood; Kidney; Pharmacology; Physiology; Renal Aminoacidurias; Salicylates; Uric Acid; Urine; Urologic Diseases | 1964 |
FACTORS INFLUENCING THE PLASMA SALICYLATE CONCENTRATION AND URINARY SALICYLATE EXCRETION AFTER ORAL DOSAGE WITH ASPIRIN.
Topics: Absorption; Aluminum; Aspirin; Biomedical Research; Blood Chemical Analysis; Humans; Metabolism; Salicylates; Urine | 1964 |
STUDIES OF DELAYED ACTION MEDICATION. IV. SALICYLATES.
Topics: Aspirin; Biomedical Research; Delayed-Action Preparations; Humans; Pharmacology; Salicylates | 1964 |
[SURFACE TENSION AND THE FORMATION OF MOLECULAR COMPOUNDS. IV. MOLECULAR ASSOCIATIONS OF CAFFEINE].
Topics: Acetanilides; Antipyrine; Aspirin; Benzene; Benzoates; Caffeine; Chemical Phenomena; Chemistry, Physical; Chloral Hydrate; Cinnamates; Research; Resorcinols; Salicylamides; Salicylates; Surface Tension; Urethane | 1964 |
BIRCH POLLEN AND ASPIRIN PSORIASIS. A STUDY IN SALICYLATE HYPERSENSITIVITY.
Topics: Aspirin; Betula; Chemical Phenomena; Chemistry; Child; Drug Hypersensitivity; Drug Tolerance; Pollen; Psoriasis; Research; Salicylates; Toxicology | 1964 |
ALKALINE DIURESIS IN TREATMENT OF ASPIRIN POISONING.
Topics: Aspirin; Bicarbonates; Blood Chemical Analysis; Blood Gas Analysis; Body Fluids; Carbon Dioxide; Diuresis; Glucose; Humans; Hydrogen-Ion Concentration; Injections, Intravenous; Isotonic Solutions; Potassium; Salicylates; Statistics as Topic; Toxicology; Urine; Water-Electrolyte Balance | 1964 |
SUSTAINED-RELEASE ASPIRIN TABLET USING AN INSOLUBLE MATRIX.
Topics: Aspirin; Biomedical Research; Blood Chemical Analysis; Carbon Isotopes; Chemistry, Pharmaceutical; Delayed-Action Preparations; Intestinal Absorption; Pharmacy; Polyvinyls; Rats; Research; Salicylates; Sulfur Isotopes; Tablets; Toxicology; Urine | 1964 |
A MICRO METHOD FOR ANALYSIS OF PLASMA SALICYLATE.
Topics: Aspirin; Blood Chemical Analysis; Humans; Microchemistry; Plasma; Research; Salicylates | 1964 |
BLOOD SALICYLATE DURING PREGNANCY.
Topics: Animals; Aspirin; Blood Chemical Analysis; Female; Humans; Metabolism; Pregnancy; Pregnancy, Animal; Rabbits; Rats; Research; Salicylates | 1964 |
ALKALINE DIURESIS FOR ASPIRIN POISONING.
Topics: Alkalies; Aspirin; Diuresis; Gastric Lavage; Salicylates; Stomach; Therapeutic Irrigation; Toxicology | 1964 |
ALKALINE DIURESIS FOR ASPIRIN POISONING.
Topics: Administration, Intravenous; Aspirin; Bicarbonates; Diuresis; Glucose; Humans; Injections; Injections, Intravenous; Potassium; Salicylates; Toxicology | 1964 |
SALICYLATE POISONING: THE DIAGNOSIS WHEN ITS POSSIBILITY IS DENIED BY THE PARENTS.
Topics: Aspirin; Child; Coma; Diabetic Coma; Diagnosis; Diagnosis, Differential; Humans; Hyperglycemia; Infant; Parent-Child Relations; Parents; Poisoning; Salicylates; Toxicology; Urine | 1964 |
PHENACETIN NEPHROPATHY.
Topics: Acidosis; Animals; Aspirin; Bacteriuria; Biological Transport; Caffeine; Codeine; Dogs; Drug Therapy; Headache; Humans; Kidney Diseases; Kidney Papillary Necrosis; Kidney Tubules; Metabolism; Neoplasm Recurrence, Local; Neoplasms; Phenacetin; Polyuria; Proteinuria; Pyuria; Salicylates; Sodium; Toxicology | 1965 |
PAIN RELIEVING DRUGS: THE NEW VERSUS THE OLD.
Topics: Analgesics; Analgesics, Non-Narcotic; Aniline Compounds; Antipyretics; Aspirin; Humans; Morphine; Muscle Relaxants, Central; Narcotics; Pain; Pyrazoles; Salicylates; Tranquilizing Agents | 1964 |
[RESULTS OF THE GASTROTEST IN 200 CASES OF PRIMARY CHRONIC POLYARTHRITIS].
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Drug Therapy; Gastric Acidity Determination; Salicylates | 1964 |
SALICYLATES AND HYPOGLYCEMIA.
Topics: Aspirin; Blood Chemical Analysis; Hypoglycemia; Infant; Insulin; Poisoning; Salicylates; Toxicology | 1965 |
[LIGHT AND ELECTRON MICROSCOPIC STUDIES ON THE LOCAL EFFECT OF SOME SALICYLATES ON THE GASTROINTESTINAL MUCOSA].
Topics: Aspirin; Electrons; Gastrointestinal Tract; Guinea Pigs; Microscopy; Microscopy, Electron; Mucous Membrane; Pharmacology; Rats; Research; Salicylamides; Salicylates; Salicylic Acid; Toxicology | 1964 |
TERATOGENIC ACTION OF SALICYLATES RELATED TO THE INHIBITION OF MUCOPOLYSACCHARIDE SYNTHESIS.
Topics: Abnormalities, Drug-Induced; Aspirin; Blood Vessels; Carbohydrate Metabolism; Glycosaminoglycans; Mice; Pharmacology; Pregnancy; Pregnancy, Animal; Research; Ribs; Salicylates; Salicylic Acid; Spine; Teratogens; Toxicology | 1965 |
[EXPERIMENTAL INFLAMMATION INDUCED BY A HEPARIN ANALOG. A TEST OF ANTI-INFLAMMATORY ACTIVITY].
Topics: Amodiaquine; Anti-Allergic Agents; Anti-Inflammatory Agents; Aspirin; Chemistry, Pharmaceutical; Colchicine; Desoxycorticosterone; Dexamethasone; Heparin; Histamine H1 Antagonists; Hydrocortisone; Inflammation; Phenylbutazone; Prednisolone; Promethazine; Quinine; Rats; Research; Salicylates | 1964 |
SITE OF ACTION OF NARCOTIC AND NON-NARCOTIC ANALGESICS DETERMINED BY BLOCKING BRADYKININ-EVOKED VISCERAL PAIN.
Topics: Amphetamine; Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Aspirin; Azepines; Bradykinin; Cats; Dextropropoxyphene; Dogs; Levorphanol; Meperidine; Morphine; Narcotics; Pain; Phenylbutazone; Physiology; Piperazines; Research; Salicylates; Sensory Receptor Cells; Spleen; Visceral Pain | 1964 |
CALCULATION OF KINETIC CONSTANTS FROM BLOOD LEVELS OF DRUGS.
Topics: Animals; Aspirin; Blood; Computers; Dogs; Electronic Data Processing; Kinetics; Pentobarbital; Pharmacology; Physics; Piperazines; Research; Salicylates; Statistics as Topic | 1964 |
INTER- AND INTRASUBJECT VARIATIONS IN DRUG ABSORPTION KINETICS.
Topics: Aspirin; Biomedical Research; Blood Chemical Analysis; Humans; Intestinal Absorption; Kinetics; Salicylates; Tablets | 1964 |
ASPIRIN FORMULATION AND ABSORPTION RATE. I. CRITERIA FOR SERUM MEASUREMENTS WITH HUMAN PANELS.
Topics: Aspirin; Biomedical Research; Blood Chemical Analysis; Chemistry, Pharmaceutical; Humans; Intestinal Absorption; Salicylates; Tablets | 1964 |
ASPIRIN FORMULATION AND ABSORPTION RATE. II. INFLUENCE ON SERUM LEVELS OF TABLETS, ANTACIDS, AND SOLUTIONS.
Topics: Antacids; Aspirin; Biomedical Research; Blood Chemical Analysis; Chemistry, Pharmaceutical; Humans; Intestinal Absorption; Salicylates; Solutions; Tablets | 1964 |
EFFECT OF SERUM BINDING ON THE DISTRIBUTION OF PENICILLINS IN THE RABBIT.
Topics: Animals; Antifungal Agents; Aspirin; Blood Proteins; Brain; Carbon Isotopes; Cresols; Kidney; Liver; Lung; Metabolism; Muscles; Myocardium; Penicillin G; Penicillin V; Penicillins; Pharmacology; Pyrazoles; Rabbits; Research; Salicylates; Streptococcus; Sulfathiazoles | 1965 |
INHIBITORS OF PENICILLIN BINDING TO SERUM PROTEINS.
Topics: Acetazolamide; Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antimetabolites; Aspirin; Benzoates; Biguanides; Blood Proteins; Carbon Isotopes; Chlorothiazide; Diuretics; Ethacrynic Acid; Guanidines; Oxazoles; p-Aminohippuric Acid; Penicillin G; Penicillin V; Penicillins; Pharmacology; Phenylbutazone; Probenecid; Rabbits; Research; Salicylates; Sulfinpyrazone; Sulfonamides; Tolbutamide | 1965 |
SALICYLATE, A POWERFUL INHIBITOR OF FREE FATTY ACID RELEASE.
Topics: Adipose Tissue; Adrenalectomy; Adrenocorticotropic Hormone; Antimetabolites; Aspirin; Benzoates; Chlorpromazine; Cold Temperature; Fasting; Fatty Acids; Fatty Acids, Nonesterified; Lipid Metabolism; Norepinephrine; Pharmacology; Propylthiouracil; Rats; Research; Salicylates; Sodium Salicylate | 1964 |
ENCEPHALOPATHY AND FATTY DEGENERATION OF THE VISCERA.
Topics: Aspirin; Brain Diseases; Carbohydrate Metabolism; Coma; Fatty Liver; Heart Diseases; Humans; Kidney Diseases; Salicylates; Toxicology; Viscera | 1965 |
SALICYLATE POISONING.
Topics: Acid-Base Equilibrium; Aspirin; Child; Diagnosis; Drug Therapy; Emetics; Gastric Lavage; Humans; Poisoning; Salicylates; Toxicology | 1965 |
SALICYLATE THERAPY.
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Drug Therapy; Salicylates; Toxicology | 1965 |
SALICYLATE THERAPY IN RHEUMATOID ARTHRITIS.
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Dosage Forms; Drug Therapy; Geriatrics; Humans; Salicylates | 1965 |
ABSORPTION AND METABOLISM OF ASPIRIN ADMINISTERED IN ENTERIC-COATED TABLETS.
Topics: Absorption; Aspirin; Biological Transport; Blood Chemical Analysis; Fluids and Secretions; Humans; Metabolism; Pharmacology; Salicylates; Solutions; Tablets; Tablets, Enteric-Coated | 1965 |
[ASPIRIN POISONING. APROPOS OF 42 CASES].
Topics: Adolescent; Aspirin; Poisoning; Salicylates; Toxicology | 1965 |
SALICYLATE THERAPY.
Topics: Aspirin; Humans; Salicylates | 1965 |
A KINETIC STUDY OF THE ELIMINATION OF SALICYLATE IN MAN.
Topics: Aspirin; Biological Transport; Body Fluids; Fluids and Secretions; Humans; Kinetics; Male; Metabolism; Research; Salicylates; Salicylic Acid; Urine | 1965 |
DAMAGE TO THE GASTRIC MUCOSA: EFFECTS OF SALICYLATES AND STIMULATION.
Topics: Absorption; Animals; Aspirin; Bethanechol Compounds; Denervation; Dogs; Gastric Mucosa; Gastrins; Gastrointestinal Hemorrhage; Hemorrhage; Histamine; Intestinal Absorption; Ion Exchange; Pharmacology; Research; Salicylates; Salicylic Acid; Sympathomimetics; Toxicology | 1965 |
SALICYLATE OTOTOXICITY: A CLINICAL STUDY.
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Audiometry; Blood; Cochlea; Drug Therapy; Enzyme Inhibitors; Geriatrics; Hearing Disorders; Hearing Tests; Humans; Oxidoreductases; Salicylates; Tinnitus; Toxicology | 1965 |
ACUTE SALICYLATE INTOXICATION: EFFECT ON THE DIRECT EOSINOPHIL COUNT.
Topics: Aspirin; Drug-Related Side Effects and Adverse Reactions; Eosinophils; Leukocyte Count; Poisoning; Psychoses, Substance-Induced; Salicylates; Toxicology | 1965 |
[Aspirin poisoning in children; report of a case].
Topics: Aspirin; Child; Humans; Salicylates | 1954 |
Barbiturate and aspirin poisoning.
Topics: Aspirin; Barbiturates; Humans; Poisoning; Salicylates | 1955 |
Modification of the respiratory response to carbon dioxide by salicylate.
Topics: Aspirin; Carbon Dioxide; Cell Respiration; Medulla Oblongata; Respiration; Salicylates | 1955 |
[Electivity of the adrenocorticotropic effect of some antirheumatic drugs: sodium salicylate, aspirin, pyramidone, M.G. 1039 (endopyrine), and butazolidine].
Topics: Aminopyrine; Analgesics; Antipyrine; Antirheumatic Agents; Aspirin; Salicylates; Sodium Salicylate; Stress, Physiological | 1955 |
PRECAUTIONS regarding salicylates, including aspirin.
Topics: Aspirin; Child; Humans; Infant; Poisoning; Salicylates | 1955 |
On the effects of SKF 525-A, caronamide, probenecid, salicylate and aspirin on the bioacetylation of sulfanilamide and choline.
Topics: Aspirin; Cardiovascular Agents; Choline; Muscle Relaxants, Central; Probenecid; Salicylates; Sulfanilamide; Sulfanilamides | 1959 |
Preliminary pharmacological comparison of choline salicylate with acetylsalicylic acid.
Topics: Aspirin; Choline; Drug Combinations; Salicylates | 1960 |
Gastritis hemorrhagica medicamentosa salicylas.
Topics: Aspirin; Gastritis; Gastrointestinal Hemorrhage; Humans; Salicylates | 1962 |
Combined salicylate, corticotropin and corticosteroid therapy in acute monocyclic rheumatic pancarditis. A preliminary report.
Topics: Adrenocorticotropic Hormone; Aspirin; Cortisone; Myocarditis; Rheumatic Fever; Rheumatic Heart Disease; Salicylates | 1961 |
[Pediatric practice. Special risks of various drugs. II. Asprin and salicylates, bismuth subnitrate].
Topics: Antacids; Antidiarrheals; Aspirin; Bismuth; Humans; Nitrates; Risk; Salicylates | 1962 |
The anti-inflammatory effect of salicylates in polymyositis.
Topics: Aspirin; Humans; Myositis; Polymyositis; Salicylates | 1962 |
Should aspirin be used to counteract 'salicylate deficiency'?
Topics: Alzheimer Disease; Aspirin; Cardiovascular Diseases; Chronic Disease; Fruit; Humans; Neoplasms; Public Health; Salicylates; Vegetables | 2003 |
The problem of aspirin allergy with a report on skin testing with salicylate-containing human sera.
Topics: Aspirin; Drug Hypersensitivity; Humans; Hypersensitivity; Salicylates; Skin; Skin Tests | 1950 |
Observations on the synergistic effect of salicylate and dicoumarol of the depression of plasma prothrombin activity in humans.
Topics: Aspirin; Blood Coagulation; Blood Coagulation Tests; Dicumarol; Prothrombin; Salicylates | 1950 |
[Comparison of the antipyretic effect of N. acetylsalicylamide, amidofebrine, acetylsalicylic acid, gentisic acid and antipyrine].
Topics: Antipyretics; Antipyrine; Aspirin; Gentisates; Salicylates | 1950 |
A case of aspirin poisoning.
Topics: Aspirin; Humans; Salicylates | 1951 |
Good old aspirin.
Topics: Aspirin; Rheumatic Fever; Salicylates | 1951 |
[Aspirin and salicylates; present view of their biological effect].
Topics: Aspirin; Humans; Salicylates; Salicylic Acid | 1951 |
Plasma-salicylate concentrations after small doses of acetylsalicylic acid.
Topics: Aspirin; Humans; Plasma; Salicylates | 1951 |
[Eosinophilopenic activity of sodium salicylate & sodium acetylsalicylate].
Topics: Aspirin; Eosinophils; Leukocyte Count; Salicylates; Sodium; Sodium Salicylate | 1951 |
The influence of sodium salicylate and acetyl salicylic acid on the release of histamine in anaphylaxis.
Topics: Anaphylaxis; Aspirin; Histamine; Humans; Hypersensitivity; Immune System Diseases; Salicylates; Sodium Salicylate | 1951 |
Hematuria, hypoprothrombinemia and salicylate medication.
Topics: Aspirin; Hematuria; Hemostatics; Humans; Hypoprothrombinemias; Prothrombin; Salicylates | 1952 |
Acute salicylate poisoning in children; a report of six cases.
Topics: Aspirin; Child; Humans; Salicylates | 1952 |
Aspirin poisoning.
Topics: Aspirin; Salicylates | 1952 |
Aspirin: it's hard to beat.
Topics: Aspirin; Cerebral Infarction; Humans; Pilot Projects; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Salicylates; Stroke; Treatment Outcome | 2004 |
[Reversible hearing loss in acute salicylate intoxication].
Topics: Adaptation, Physiological; Adult; Aspirin; Drug Overdose; Hearing Loss; Humans; Male; Otoacoustic Emissions, Spontaneous; Salicylates; Tinnitus | 2004 |
Effects of triflusal on oxidative stress, prostaglandin production and nitric oxide pathway in a model of anoxia-reoxygenation in rat brain slices.
Topics: Analysis of Variance; Animals; Aspirin; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hypoxia; In Vitro Techniques; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Oxygen; Platelet Aggregation Inhibitors; Prostaglandins; Rats; Rats, Wistar; Salicylates | 2004 |
An evaluation of reported poisonings by acetylsalicylic acid.
Topics: Aspirin; Salicylates | 1950 |
Aspirin inhibits ox-LDL-mediated LOX-1 expression and metalloproteinase-1 in human coronary endothelial cells.
Topics: Anions; Aspirin; Cells, Cultured; Coronary Vessels; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Humans; Indomethacin; Lipoproteins, LDL; Matrix Metalloproteinase 1; p38 Mitogen-Activated Protein Kinases; Receptors, LDL; Receptors, Oxidized LDL; Salicylates; Scavenger Receptors, Class E; Superoxides; Time Factors | 2004 |
Reconsidering combined antiplatelet and anticoagulant therapy in atrial fibrillation.
Topics: Acenocoumarol; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; International Normalized Ratio; Male; Middle Aged; Mitral Valve Stenosis; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Salicylates; Warfarin | 2004 |
Aspirin, other salicylates and non-steroidal anti-inflammatory agents.
Topics: Acidosis; Adult; Alkalosis, Respiratory; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Charcoal; Child; Drug Overdose; Humans; Salicylates; Sorption Detoxification | 2004 |
Protective effect of triflusal and its main metabolite HTB in an in vitro model of anoxia-reoxygenation in rat brain slices: comparison with acetylsalicylic and salicylic acids.
Topics: Animals; Aspirin; Brain Chemistry; Dinoprostone; Glutathione; Hypoxia, Brain; In Vitro Techniques; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Nerve Tissue Proteins; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Reperfusion Injury; Salicylates; Thiobarbituric Acid Reactive Substances | 2005 |
Production of antioxidant compounds by culture of Panax ginseng C.A. Meyer hairy roots: I. Enhanced production of secondary metabolite in hairy root cultures by elicitation.
Topics: Antioxidants; Aspirin; Cell Culture Techniques; Cell Proliferation; Dose-Response Relationship, Drug; Panax; Plant Roots; Rhizobium; Salicylates; Salicylic Acid; Saponins; Yeasts | 2005 |
[Simultaneous determination of aspirin and salicyclic acid by synchronous fluorescence spectrometry].
Topics: Aspirin; Reproducibility of Results; Salicylates; Spectrometry, Fluorescence | 2005 |
Detection of aspirin resistance by PFA-100: prevalence and aspirin compliance in patients with chronic stable angina.
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Case-Control Studies; Female; Humans; Male; Middle Aged; Myocardial Infarction; Nitrates; Patient Compliance; Platelet Aggregation Inhibitors; Platelet Function Tests; Prevalence; Reference Values; Salicylates; Time Factors | 2005 |
Pro-apoptotic effect of a nitric oxide-donating NSAID, NCX 4040, on bladder carcinoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Aspirin; Cell Cycle; Cell Line, Tumor; Humans; In Situ Nick-End Labeling; Membrane Potentials; Nitric Oxide; Nitro Compounds; Salicylates; Urinary Bladder Neoplasms | 2005 |
Effects of different aspirin formulations on platelet aggregation times and on plasma salicylate concentrations.
Topics: Administration, Oral; Adolescent; Adult; Arachidonic Acid; Aspirin; Cross-Over Studies; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Prospective Studies; Reference Values; Salicylates; Single-Blind Method; Solubility; Tablets, Enteric-Coated; Time Factors | 2006 |
Gaultherin, a natural salicylate derivative from Gaultheria yunnanensis: towards a better non-steroidal anti-inflammatory drug.
Topics: Abdominal Pain; Acetic Acid; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromatography, High Pressure Liquid; Croton Oil; Disaccharides; Disease Models, Animal; Ear Diseases; Esterases; Gastric Mucosa; Gaultheria; Glycoside Hydrolases; Humans; Immersion; Inflammation; Intestines; Male; Mice; Plant Leaves; Plant Stems; Rats; Rats, Wistar; Restraint, Physical; Salicylates; Stomach Ulcer; Stress, Psychological; Water | 2006 |
Inhibition of cardiac hypertrophy by triflusal (4-trifluoromethyl derivative of salicylate) and its active metabolite.
Topics: Animals; Aspirin; Base Sequence; Cardiomegaly; DNA Primers; Electrophoretic Mobility Shift Assay; Immunoprecipitation; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; RNA Processing, Post-Transcriptional; Salicylates; Signal Transduction | 2006 |
Molecular characterization of cytotoxic and resistance mechanisms induced by NCX 4040, a novel NO-NSAID, in pancreatic cancer cell lines.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase 9; Cell Cycle; Cell Line, Tumor; Cytotoxins; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Nitric Oxide Donors; Nitro Compounds; Pancreatic Neoplasms; S-Nitroso-N-Acetylpenicillamine; Salicylates | 2006 |
Effect of human serum albumin on drug metabolism: structural evidence of esterase activity of human serum albumin.
Topics: Aspirin; Crystallography; Esterases; Humans; Inactivation, Metabolic; Models, Molecular; Myristic Acid; Protein Binding; Salicylates; Serum Albumin | 2007 |
Marked prevention of ischemic brain injury by Neu2000, an NMDA antagonist and antioxidant derived from aspirin and sulfasalazine.
Topics: Animals; Antioxidants; Aspirin; Benzoates; Brain Ischemia; Cells, Cultured; Excitatory Amino Acid Antagonists; Fluorobenzenes; Infarction, Middle Cerebral Artery; meta-Aminobenzoates; Mice; N-Methylaspartate; Oxidative Stress; Receptors, N-Methyl-D-Aspartate; Salicylates; Sulfasalazine | 2007 |
Effects of triflusal and aspirin in a rat model of cerebral ischemia.
Topics: Animals; Aspirin; Brain Ischemia; Disease Models, Animal; Drug Therapy, Combination; Male; Rats; Rats, Wistar; Salicylates | 2007 |
Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Death; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Inflammation; Male; NF-kappa B; NF-kappa B p50 Subunit; Protein Transport; Random Allocation; Rats; Rats, Inbred Lew; Retina; Retinal Ganglion Cells; Salicylates; Sodium Salicylate; Sulfasalazine; Transcription Factor RelA | 2007 |
[Milestones of cardivascular pharmacotherapy: salicylates and aspirin].
Topics: Aspirin; Cardiovascular Diseases; History, 18th Century; History, 19th Century; History, 20th Century; Humans; Salicylates | 2006 |
Analgesic and anti-inflammatory activities of a fraction rich in gaultherin isolated from Gaultheria yunnanensis (FRANCH.) REHDER.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Croton Oil; Disaccharides; Dose-Response Relationship, Drug; Ear; Edema; Female; Formaldehyde; Gaultheria; Glycosides; Hindlimb; Indomethacin; Male; Mice; Mice, Inbred Strains; Molecular Structure; Pain; Rats; Rats, Wistar; Salicylates | 2007 |
The study of the influence of surfactant charge on alkaline hydrolysis reactions of acetylsalicylic acid (ASA) and triflusal (TFL) using spectrophotometric methods.
Topics: Algorithms; Alkalies; Aspirin; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Platelet Aggregation Inhibitors; Polyethylene Glycols; Quaternary Ammonium Compounds; Salicylates; Salicylic Acid; Sodium Dodecyl Sulfate; Sodium Hydroxide; Spectrophotometry, Ultraviolet; Static Electricity; Surface-Active Agents; Water | 2007 |
Inhibition of Anaphylactic Shock by Acetylsalicylic Acid.
Topics: Anaphylaxis; Aspirin; Hypersensitivity; Immune System Diseases; Salicylates | 1948 |
Estimation of hydroxyl radical generation by salicylate hydroxylation method in kidney of mice exposed to ferric nitrilotriacetate and potassium bromate.
Topics: Animals; Aspirin; Bromates; Comet Assay; DNA Adducts; DNA Damage; Ferric Compounds; Hydroxyl Radical; Hydroxylation; Kidney; Kidney Function Tests; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Mixed Function Oxygenases; Nitrilotriacetic Acid; Salicylates | 2007 |
The aspirin metabolite salicylate enhances neuronal excitation in rat hippocampal CA1 area through reducing GABAergic inhibition.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Electrophysiology; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; Male; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Salicylates; Synaptic Transmission | 2008 |
Noninvasive quantitation of drug concentration in prostate and seminal vesicles: improvement and validation with desipramine and aspirin.
Topics: Administration, Oral; Adolescent; Adult; Algorithms; Aspirin; Bayes Theorem; Biomarkers, Pharmacological; Chromatography; Desipramine; Ejaculation; Fructose; HIV Infections; Humans; Male; Middle Aged; Outpatients; Prostate; Prostate-Specific Antigen; Reproducibility of Results; Salicylates; Semen; Seminal Vesicles; Sexual Dysfunction, Physiological; Tandem Mass Spectrometry | 2008 |
Marked hypoprothrombinemia with hemorrhagic manifestations due to acetylsalicylic acid; report of a case.
Topics: Aspirin; Blood Coagulation; Hemorrhage; Hypoprothrombinemias; Salicylates | 1948 |
Effect of acetyl salicylic acid on the gastric mucosa of the Shay rat.
Topics: Animals; Aspirin; Bile Ducts; Calculi; Gastric Mucosa; Mucous Membrane; Rats; Salicylates; Stomach | 1949 |
Acute acetylsalicylic acid intoxication; report of five cases with two deaths.
Topics: Aspirin; Death; Salicylates | 1949 |
Aspirin poisoning.
Topics: Aspirin; Salicylates | 1949 |
Protective effects of triflusal on secondary thrombus growth and vascular cyclooxygenase-2.
Topics: Animals; Aspirin; Base Sequence; Blood Vessels; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; DNA Primers; Endothelium, Vascular; Fibrinolytic Agents; In Vitro Techniques; Male; Perfusion; Rabbits; Recurrence; RNA, Messenger; Salicylates; Thrombosis | 2008 |
Induction of paraoxonase 1 and apolipoprotein A-I gene expression by aspirin.
Topics: Animals; Apolipoprotein A-I; Aryldialkylphosphatase; Aspirin; Cell Line, Tumor; Gene Expression Regulation, Enzymologic; Gene Silencing; Hepatocytes; Humans; Mice; Rats; Receptors, Aryl Hydrocarbon; RNA, Small Interfering; Salicylates | 2008 |
The underutilization of hemodialysis in patients with salicylate poisoning.
Topics: Adult; Aspirin; Blood-Brain Barrier; Charcoal; Diagnosis, Differential; Fatal Outcome; Humans; Hypertonic Solutions; Male; Renal Dialysis; Salicylates; Sodium Bicarbonate; Suicide, Attempted; Time Factors | 2009 |
The isomers of aspirin.
Topics: Aspirin; Isomerism; Salicylates | 1948 |
Effect of acetylsalicylic acid ingestion on electrophoretic patterns of human plasma.
Topics: Aspirin; Electrophoresis; Kidney; Salicylates | 1947 |
Quantitative evaluation of analgetic action in guinea pigs; morphine, ethyl l-methyl-4-phenylpiperidine-4-carboxylate (demerol) and acetylsalicylic acid.
Topics: Analgesics; Aspirin; Guinea Pigs; Meperidine; Morphine; Piperidines; Salicylates | 1947 |
Acute acetylsalicylic acid poisoning; two cases.
Topics: Aspirin; Salicylates | 1948 |
Circulatory adjustments during treatment with large doses of sodium salicylate or acetylsalicylic acid.
Topics: Aspirin; Blood Circulation; Salicylates; Sodium Salicylate | 1947 |
Acetylsalicylic Acid (Aspirin) Toxicological, Clinical and Experimental Study.
Topics: Aspirin; Salicylates | 1948 |
Suramin in veterinary practice; identity of Bayer 205 with suramin B.P.
Topics: Aspirin; Salicylates; Suramin; Veterinary Medicine | 1947 |
Acetylosalicylic acid composite tablets Ph. H. V.
Topics: Aspirin; Salicylates | 1947 |
The question of prothrombinopenic hemorrhage from post-tonsillectomy use of chewing gum containing acetylsalicylic acid.
Topics: Aspirin; Blood; Chewing Gum; Hemorrhage; Hemostatics; Humans; Prothrombin; Salicylates; Tonsillectomy | 1948 |
Allergy to aspirin in a family; report of a case.
Topics: Aspirin; Hypersensitivity; Immune System Diseases; Salicylates | 1947 |
An examination of potentiating action of aspirin upon codeine in raising the pain threshold.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Codeine; Drug Combinations; Humans; Pain; Pain Threshold; Salicylates | 1948 |
Comparison of pharmacokinetic and pharmacodynamic profiles of aspirin following oral gavage and diet dosing in rats.
Topics: Administration, Oral; Animals; Aspirin; Colon; Diet; Dinoprostone; Dose-Response Relationship, Drug; Male; Rats; Rats, Inbred F344; Salicylates; Thromboxane B2; Time Factors | 2009 |
The woman who heard music: high salicylate levels and tinnitus.
Topics: Aged; Aspirin; Diagnosis, Differential; Female; Hallucinations; Humans; Music; Salicylates; Tinnitus | 2008 |
Aspirin and salicylates modulate IgE-mediated leukotriene secretion in mast cells through a dihydropyridine receptor-mediated Ca(2+) influx.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Calcium; Calcium Channels, L-Type; Cell Line; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorometry; Immunoglobulin E; Leukotriene C4; Mast Cells; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C3H; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phospholipases A2; Rats; Salicylates | 2009 |
Hearing loss in a woman on aspirin: the silent pharmacokinetic parameter.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Disease Progression; Female; Hearing Loss; Humans; Lupus Erythematosus, Systemic; Proteinuria; Salicylates; Tinnitus | 2009 |
Salicylates dilate blood vessels through inhibiting PYK2-mediated RhoA/Rho-kinase activation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Aspirin; Blood Pressure; Blood Vessels; Cells, Cultured; Disease Models, Animal; Focal Adhesion Kinase 2; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Salicylates; Signal Transduction; Vasoconstriction; Vasodilation | 2009 |
Plasma salicylate level and aspirin resistance in survivors of myocardial infarction.
Topics: Administration, Oral; Adult; Aged; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Salicylates | 2010 |
Long-term follow-up of atrial fibrillation patients in the NASPEAF study. Prospective evaluation of different antiplatelet treatments.
Topics: Aged; Aspirin; Atrial Fibrillation; Female; Follow-Up Studies; Humans; Male; Platelet Aggregation Inhibitors; Prospective Studies; Salicylates; Time Factors | 2009 |
Synthesis and biological evaluation of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory ac
Topics: Aspirin; Cyclooxygenase 2 Inhibitors; Humans; Isomerism; Lipoxygenase Inhibitors; Pyridones; Salicylates; Sulfonamides | 2009 |
A 19-month-old boy with recurrent respiratory distress.
Topics: Acid-Base Equilibrium; Albuterol; Alkalosis, Respiratory; Aspirin; Asthma; Bicarbonates; Bites, Human; Child Abuse; Chlorides; Developmental Disabilities; Emergencies; Humans; Hyperventilation; Infant; Male; Poisoning; Recurrence; Salicylates | 2010 |
Aspirin allergy; its relationship to chronic intractable asthma.
Topics: Aspirin; Asthma; Drug Hypersensitivity; Hypersensitivity; Salicylates | 1947 |
The assay of aspirin, acetophenetidin, and caffeine capsules.
Topics: Aspirin; Biological Assay; Caffeine; Capsules; Phenacetin; Salicylates | 1947 |
Acetylsalicylic acid poisoning with recovery.
Topics: Aspirin; Biological Phenomena; Humans; Physiological Phenomena; Salicylates | 1947 |
Acetylsalicylic acid poisoning, with a report of a fatal case.
Topics: Aspirin; Humans; Salicylates | 1947 |
The influence of acetylsalicylic acid upon analgesic effects of induced pain.
Topics: Analgesics; Anesthesia; Aspirin; Leadership; Pain; Salicylates | 1945 |
Some incompatibilities of acetyl-salicylic acid.
Topics: Aspirin; Salicylates | 1946 |
The fate of acetylsalicylic acid.
Topics: Aspirin; Salicylates | 1946 |
Oral administration of ethanol with aspirin increases the concentration of salicylic acid in plasma and organs, especially the brain, in mice.
Topics: Administration, Oral; Animals; Aspirin; Brain; Ethanol; Hippurates; Male; Mice; Mice, Inbred ICR; Salicylates; Tissue Distribution | 2010 |
The influence of acetylsalicyclic acid ingestion on the electrophoretic patterns of plasma.
Topics: Aspirin; Eating; Electrophoresis; Humans; Plasma; Salicylates | 1947 |
The hydrolysis of acetylsalicylic acid by animal tissues.
Topics: Aspirin; Hydrolysis; Salicylates | 1947 |
Electrochemical behavior of triflusal, aspirin and their metabolites at glassy carbon and boron doped diamond electrodes.
Topics: Alkalies; Aspirin; Boron; Carbon; Diamond; Electrochemistry; Electrodes; Glass; High-Throughput Screening Assays; Hydrogen-Ion Concentration; Hydrolysis; Molecular Structure; Particle Size; Salicylates; Salicylic Acid; Surface Properties; Water | 2010 |
Are there foods that should be avoided if a patient is sensitive to salicylates?
Topics: Aspirin; Food Analysis; Food Hypersensitivity; Fruit; Humans; Salicylates; Spices; Vegetables | 2010 |
Spectroscopic studies of the interaction of aspirin and its important metabolite, salicylate ion, with DNA, A·T and G·C rich sequences.
Topics: Aspirin; Base Composition; Base Sequence; Circular Dichroism; DNA; Drug Evaluation, Preclinical; Drug Interactions; Models, Biological; Nucleic Acid Conformation; Salicylates; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectrum Analysis | 2010 |
Studies on analgesics; the time-action curves of morphine, codeine, dilaudid and demerol by various methods of administration; analgesic activity of acetylsalicylic acid and aminopyrine.
Topics: Aminopyrine; Analgesics; Anesthesia; Aspirin; Codeine; Hydromorphone; Meperidine; Morphine; Salicylates | 1945 |
Acetylsalicylic acid (aspirin) as a cause of bleeding.
Topics: Aspirin; Hemorrhage; Humans; Salicylates | 1945 |
The influence of acetylsalicylic acid upon analgesic effect of induced pain.
Topics: Analgesics; Anesthesia; Anesthesiology; Aspirin; Pain; Salicylates | 1946 |
The separation of acetylsalicylic acid, acetophenetidin, and caffeine.
Topics: Aspirin; Caffeine; Phenacetin; Rare Diseases; Retinal Degeneration; Retinal Detachment; Salicylates | 1946 |
Use of salicylates in rheumatic fever; mixture of aspirin and vitamin K unwarranted.
Topics: Antifibrinolytic Agents; Aspirin; Naphthoquinones; Retinoids; Rheumatic Fever; Salicylates; Vitamin K | 1945 |
Quantitative HPLC analysis of mebeverine, mesalazine, sulphasalazine and dispersible aspirin stored in a Venalink monitored dosage system with co-prescribed medicines.
Topics: Aspirin; Capsules; Chromatography, High Pressure Liquid; Drug Stability; Drug Storage; Mass Spectrometry; Medication Systems; Mesalamine; Phenethylamines; Polypharmacy; Salicylates; Sulfasalazine; Tablets; Technology, Pharmaceutical; Time Factors | 2011 |
Postharvest treatments with salicylic acid, acetylsalicylic acid or oxalic acid delayed ripening and enhanced bioactive compounds and antioxidant capacity in sweet cherry.
Topics: Antioxidants; Aspirin; Cold Temperature; Food Preservation; Fruit; Oxalic Acid; Prunus; Salicylates | 2011 |
Letter by Borja and Garcia-Rafanell regarding article, "Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association"
Topics: Aspirin; Carotid Arteries; Clinical Trials as Topic; Endarterectomy, Carotid; Guidelines as Topic; Humans; Ischemic Attack, Transient; Platelet Aggregation Inhibitors; Salicylates; Stents; Stroke | 2011 |
High doses of salicylate and aspirin are inhibitory on acid-sensing ion channels and protective against acidosis-induced neuronal injury in the rat cortical neuron.
Topics: Acid Sensing Ion Channels; Acidosis; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Nerve Tissue Proteins; Neural Inhibition; Neurons; Patch-Clamp Techniques; Propidium; Rats; Rats, Sprague-Dawley; Salicylates; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin | 2012 |
Adherence junction proteins in angiogenesis: modulation by aspirin and salicylic acid.
Topics: Adherens Junctions; Angiogenesis Inhibitors; Antigens, CD; Aspirin; Cadherins; Catenins; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Delta Catenin; Dose-Response Relationship, Drug; Human Umbilical Vein Endothelial Cells; Humans; NADPH Oxidases; Neovascularization, Physiologic; Phosphorylation; Salicylates; Vascular Endothelial Growth Factor A | 2012 |
Is non-therapeutic aspirin use in children a problem in South Africa?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Nonprescription Drugs; Poisoning; Retrospective Studies; Salicylates; South Africa | 2011 |
In vivo impact of prodrug isosorbide-5-nicotinate-2-aspirinate on lipids and prostaglandin D2: is this a new immediate-release therapeutic option for niacin?
Topics: Animals; Apolipoproteins B; Aspirin; Blood Glucose; Chemistry, Pharmaceutical; Cholesterol, LDL; Cyclooxygenase Inhibitors; Hyperglycemia; Hypolipidemic Agents; Isosorbide; Lipid Metabolism; Lipids; Macaca fascicularis; Models, Biological; Niacin; Postprandial Period; Prodrugs; Prostaglandin D2; Salicylates; Thromboxane B2; Triglycerides | 2012 |
Salicylate poisoning.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Poisoning; Salicylates | 2012 |
The ancient drug salicylate directly activates AMP-activated protein kinase.
Topics: Amino Acid Substitution; AMP-Activated Protein Kinases; Animals; Aspirin; Binding Sites; Biphenyl Compounds; Carbohydrate Metabolism; Cell Line; Enzyme Activation; Enzyme Activators; HEK293 Cells; Humans; Lipid Metabolism; Liver; Mice; Mice, Knockout; Mutation; Oxygen Consumption; Phosphorylation; Pyrones; Rats; Salicylates; Thiophenes | 2012 |
Prevalence of high platelet reactivity in aspirin-treated patients referred for coronary angiography.
Topics: Aged; Aspirin; Collagen; Coronary Angiography; Coronary Artery Disease; Drug Resistance; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Risk Factors; Salicylates | 2013 |
Adherence junction proteins in angiogenesis: modulation by aspirin and salicylic acid.
Topics: Adherens Junctions; Angiogenesis Inhibitors; Antigens, CD; Aspirin; Cadherins; Catenins; Human Umbilical Vein Endothelial Cells; Humans; Neovascularization, Physiologic; Salicylates | 2013 |
Evaluation of the pharmacological properties of salicylic acid-derivative organoselenium: 2-hydroxy-5-selenocyanatobenzoic acid as an anti-inflammatory and antinociceptive compound.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Behavior, Animal; Brain; Drug Evaluation, Preclinical; Gastric Mucosa; Liver; Male; Mice; Organoselenium Compounds; Pain Measurement; Peroxidase; Reactive Nitrogen Species; Salicylates | 2014 |
Selective cyclooxygenase-1 inhibition by p6 and gastrotoxicity: preliminary investigation.
Topics: Animals; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Ethylene Glycols; Gastric Mucosa; Male; Membrane Proteins; Mice; Salicylates | 2015 |
Inhibition of human alcohol and aldehyde dehydrogenases by aspirin and salicylate: assessment of the effects on first-pass metabolism of ethanol.
Topics: Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Aspirin; Dose-Response Relationship, Drug; Ethanol; Humans; Salicylates | 2015 |
[ATl- and calcium-dependent mechanisms of salicy- lates influence on electric potentials of neurons in mollusk Helix albescens].
Topics: Animals; Aspirin; Calcium; Cobalt; Electricity; Helix, Snails; Neurons; Salicylates; Zinc | 2015 |
Complexation induced fluorescence and acid-base properties of dapoxyl dye with γ-cyclodextrin: a drug-binding application using displacement assays.
Topics: Acetaminophen; Ampicillin; Aspirin; beta-Cyclodextrins; Binding Sites; Chloramphenicol; Drug Delivery Systems; Fluorescence; Fluorescent Dyes; Fluorometry; Hydrogen-Ion Concentration; Ibuprofen; Kanamycin; Oxazines; Oxazoles; Piroxicam; Salicylates; Salicylic Acid; Sorbic Acid; Sulfonamides; Thiamphenicol; Xanthenes | 2015 |
Aspirin and salicylic acid decrease c-Myc expression in cancer cells: a potential role in chemoprevention.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Chromatography, High Pressure Liquid; Down-Regulation; Fluorescent Antibody Technique; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Proto-Oncogene Proteins c-myc; Salicylates | 2016 |
Absorption of salicylate powders versus tablets following overdose: a poison center observational study.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Overdose; Female; Humans; Male; Middle Aged; Poison Control Centers; Powders; Renal Dialysis; Retrospective Studies; Salicylates; Tablets; Time Factors; Young Adult | 2016 |
Delayed Salicylate Toxicity in a 17-Year-Old Girl With Initially Undetectable Salicylate Concentration 3.9 Hours After Ingestion.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Overdose; Female; Humans; Salicylates; Time Factors | 2017 |
Neuroprotective effect of triflusal and its main metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid (HTB), in the postischemic brain.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Brain; Brain Ischemia; Cytokines; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Rats, Sprague-Dawley; Salicylates | 2017 |
Quantitative determination of five metabolites of aspirin by UHPLC-MS/MS coupled with enzymatic reaction and its application to evaluate the effects of aspirin dosage on the metabolic profile.
Topics: Animals; Aspirin; Chromatography, High Pressure Liquid; Glucuronates; Glucuronidase; Glucuronides; Hippurates; Male; Metabolome; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Tandem Mass Spectrometry | 2017 |
Aspirin desensitization in patients with coronary artery disease: Cost savings.
Topics: Aspirin; Clopidogrel; Coronary Disease; Cost Savings; Desensitization, Immunologic; Drug Hypersensitivity; Drug Substitution; Humans; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Salicylates; Ticlopidine | 2017 |
Salicylate Food Intolerance and Aspirin Hypersensitivity in Nasal Polyposis.
Topics: Adult; Allergens; Aspirin; Cross-Sectional Studies; Drug Hypersensitivity; Female; Food Hypersensitivity; Humans; Iran; Male; Middle Aged; Nasal Polyps; Prognosis; Salicylates; Skin Tests | 2017 |
Triflusal in Patients With Aspirin Hypersensitivity Treated With Coronary Stent Implantation.
Topics: Aged; Aspirin; Drug Hypersensitivity; Female; Fibrinolytic Agents; Graft Occlusion, Vascular; Humans; Male; Myocardial Ischemia; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Salicylates; Stents | 2018 |
Spurious Hyperchloremia in the Presence of Elevated Plasma Salicylate: A Cohort Study.
Topics: Acidosis; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bromides; Chlorides; Cohort Studies; Databases, Factual; False Positive Reactions; Female; Humans; Male; Middle Aged; Retrospective Studies; Salicylates; Water-Electrolyte Imbalance; Young Adult | 2018 |
Clopidogrel and Low-Dose Aspirin, Alone or Together, Reduce Risk of Colorectal Cancer.
Topics: Aged; Aged, 80 and over; Aspirin; Case-Control Studies; Clopidogrel; Colorectal Neoplasms; Dual Anti-Platelet Therapy; Female; Humans; Logistic Models; Male; Middle Aged; Platelet Aggregation Inhibitors; Protective Factors; Risk Reduction Behavior; Salicylates; Spain | 2019 |
A novel mechanism for the anticancer activity of aspirin and salicylates.
Topics: Aspirin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Cyclin D1; Drug Screening Assays, Antitumor; EGF Family of Proteins; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; NF-kappa B; Phosphorylation; Salicylates; Signal Transduction | 2019 |
Salicylate toxicity following undetectable concentrations.
Topics: Aspirin; Salicylates | 2020 |
Sulfosalicylic acid/Fe
Topics: Antineoplastic Agents; Aspirin; Benzenesulfonates; Chemoprevention; Humans; Hydrogen Peroxide; Iron; MCF-7 Cells; Oxidative Stress; Polyethylene Glycols; Reactive Oxygen Species; Salicylates | 2019 |
Preharvest application of methyl salicylate, acetyl salicylic acid and salicylic acid alleviated disease caused by Botrytis cinerea through stimulation of antioxidant system in table grapes.
Topics: Antioxidants; Aspirin; Botrytis; Disease Resistance; Food Preservation; Phenols; Plant Diseases; Salicylates; Salicylic Acid; Vitis | 2020 |
Triflusal in Patients with Acute Coronary Syndrome and Acetylsalicylic Acid Hypersensitivity.
Topics: Acute Coronary Syndrome; Aspirin; Drug Therapy, Combination; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Retrospective Studies; Salicylates; Treatment Outcome | 2021 |
Pseudohyperchloremia and Negative Anion Gap - Think Salicylate!
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Artifacts; Aspirin; Chlorides; Equipment Failure Analysis; Female; Humans; Ion-Selective Electrodes; Male; Middle Aged; Patient Care; Salicylates; Suicide, Attempted | 2021 |
Activated Charcoal and Bicarbonate for Aspirin Toxicity: a Retrospective Series.
Topics: Adult; Aspirin; Bicarbonates; Charcoal; Female; Humans; Retrospective Studies; Salicylates | 2022 |
Reflections on Aspirin Toxicity: Interpreting Effects of Sodium Bicarbonate and Activated Charcoal.
Topics: Aspirin; Charcoal; Humans; Salicylates; Sodium Bicarbonate | 2022 |
Downbeat Nystagmus and Bilateral Sudden Hearing Loss by Suicidal Aspirin Intoxication.
Topics: Aspirin; Hearing Loss, Bilateral; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Humans; Nystagmus, Pathologic; Salicylates; Suicidal Ideation | 2022 |
Medical Outcomes of Acute Aspirin Single Substance Poisoning in Pediatric Patients.
Topics: Ambulatory Care; Aspirin; Child; Child, Preschool; Evidence-Based Medicine; Humans; Poison Control Centers; Salicylates | 2023 |
Incidence of rebound salicylate toxicity following cessation of urine alkalinization.
Topics: Aspirin; Drug Overdose; Humans; Incidence; Salicylates; Sodium Bicarbonate | 2023 |
Salicylate induces AMPK and inhibits c-MYC to activate a NRF2/ARE/miR-34a/b/c cascade resulting in suppression of colorectal cancer metastasis.
Topics: AMP-Activated Protein Kinases; Aspirin; Cell Line, Tumor; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; NF-E2-Related Factor 2; Salicylates; Tumor Suppressor Protein p53 | 2023 |