aspirin and ranitidine

aspirin has been researched along with ranitidine in 100 studies

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-199031 (31.00)18.7374
1990's21 (21.00)18.2507
2000's27 (27.00)29.6817
2010's18 (18.00)24.3611
2020's3 (3.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Faassen, F; Spanings, H; Vogel, G; Vromans, H1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Borisevich, SS; Burgart, YV; Khursan, SL; Krasnykh, OP; Ljushina, GA; Markova, LN; Maslova, VV; Saloutin, VI; Shchegol'kov, EV; Shchur, IV; Solodnikov, SY; Trefilova, AN1
Balliano, TL; Barbosa, G; Carvalho, VF; da Silva, BA; de Souza, ET; Lima, LM; Martins, IRR; Martins, MA; Medeiros, MM; Moraes Junior, MO; Nunes, IKDC; Silva, PMR; Silva, SWD1
Brundell, S; Cole, AT; Hawkey, CJ; Hawthorne, AB; Hudson, N; Mahida, YR2
Decktor, DL; Fitzpatrick, LR1
Bergdolt, H; Dammann, HG; Müller, P; Simon, B2
Jones, G; O'Connell, D1
Paton, DM1
Brzozowski, T; Drozdowicz, D; Konturek, SJ; Nauert, C1
Anand, BS; Kumar, N; Misra, SP1
Penston, JG; Wormsley, KG1
Jorge, AD1
Buyniski, JP; Cavanagh, RL1
Daneshmend, TK; Hawkey, CJ; Kitchingman, GK; Prichard, PJ; Walt, RP1
Damman, HG; Marinis, E; Müller, P; Simon, B1
Hawkey, CJ; Marshall, S; Somerville, KW1
Bjorkman, DJ; Goo, RH; Larsen, KR; Moore, JG1
Abib, A; Canievsky, L; Casas, H; Cosen, JN; Leczycki, H; Martínez, RO; Mazure, PA1
Dammann, HG; Müller, P; Simon, B2
Hawkey, CJ; Prichard, PJ; Somerville, KW1
Katz, LB; Rosenthale, ME; Shriver, DA; Tobia, AJ1
Bjarnason, I; Levi, AJ; Peters, TJ; Smethurst, P; Williams, P1
Adler, SN; Berkowitz, JM; Sharp, JT; Warner, CW1
Bambara, LM; Caramaschi, P; Corrocher, R; Girelli, M; Lomeo, A; Pellegatti, M; Testi, R1
Goo, RH; Moore, JG1
Berkowitz, JM; Rogenes, PR; Sharp, JT; Warner, CW1
Lumachi, B; Scuri, R1
Konturek, SJ1
Bonvicini, F; Gasbarrini, G; Laschi, R; Pasquinelli, G; Zoli, G1
Schubert, TT1
Daniotti, S; Del Soldato, P; Foschi, D; Varin, L1
Brzozowski, T; Dembińska-Kieć, A; Konturek, SJ; Piastucki, I; Radecki, T; Zmuda, A2
Bunce, KT; Daly, MJ; Humphray, JM; Stables, R1
Brittain, RT; Daly, MJ1
Ohtsuki, H; Okabe, S; Tabata, K1
Konturek, SJ; Kopp, B; Kwiecień, N; Obtułowicz, W; Oleksy, J; Polański, M1
Del Soldato, P; Varin, L1
Brittain, RT; Jack, D1
Bornman, PC; Gilinsky, NH; Girdwood, AH; Lucke, W; Marks, IN; Mee, AS; Tobias, P; Wright, JP1
Montero, MJ; Palacios, B; Román, LS; Sevilla, MA1
Lee, M1
King, RL; Levine, RA; Nandi, J; Wagner, KA1
Leach, IH; Robinson, MH; Wheatley, T1
Cole, AT; Hawkey, CJ; Hudson, N; Lettis, S; Murray, FE; Turnbull, GM1
Arce, L; Jackisch, P; Müller, P; Simon, B1
Fuchs, W; Müller, P; Simon, B1
Barrett, KE; Hogan, D; Isenberg, JI; Koss, M; Myers, CP; Yao, B1
Müller, P; Simon, B1
Akiba, Y; Kaunitz, JD; Tanaka, S1
Bertaccini, G; Coppelli, G; Coruzzi, G; Frati, P1
Ayukawa, O; Kariyazono, H; Moriyama, Y; Nakamura, K; Shinkawa, T; Taira, A; Toyohira, H; Yamada, K; Yamaguchi, T; Yamashita, T; Yotsumoto, G1
Gray, DW; Morris, PJ; Nargund, V; Robertson, AJ1
Lanas, AI1
Scheiman, JM1
Matthews, JN; N'Dow, J; Neal, DE; Pearson, JP; Robson, CN1
Akay, C; Degim, T; Degim, Z; Zaimoglu, V1
Astudillo, L; Bustamante, C; Rodríguez, JA; Schmeda-Hirschmann, G1
Astudillo, L; Rodriguez, JA; Schmeda-Hirschmann, G1
Chong, WK; Dillon, MJ; Elston, J; Harris, CM; Ragge, NK; Taylor, DS1
Ajaikumar, KB; Asheef, M; Babu, BH; Padikkala, J1
Bogdal, J; Brzozowski, T; Budak, A; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Kwiecien, S; Pawlik, WW; Stachura, J; Zwolinska-Wcislo, M1
Devi, CS; Jainu, M; Mohan, KV1
Fereniec-Gołtbiewska, L; Rutkowska, M1
DeLao, T; Granada, JF; Guthikonda, S; Kleiman, A; Kleiman, NS; Lev, EI; Patel, R; Ramabadran, RS1
Sanmugapriya, E; Venkataraman, S1
Balakrishnan, S; Jhaj, R1
Gregg, PJ; Madhusudhan, TR; Rangan, A1
Sugita, K; Tokura, Y1
Gunasekaran, G; Prakash, M1
Mahmoud, H; Mnaa, S; Shaker, E1
Kato, M; Nema, H1
Das, S; Dubey, MK; Jaiswal, SK; Mishra, P; Rao, CV; Sharma, B1
Cerboni, P; Doyen, D; Ferrari, E; Moceri, P1
Covert, WM; Langley, GD; Soliman, PT; Westin, SN1
Attakora, J; Donkoh, IE; Ephraim, RKD; Essuman, G; Okyere, I; Okyere, P; Serwaa, D1
Almaghaslah, D; Khaled, A; Makki, S; Nagib, R; Siddiqua, A1

Reviews

9 review(s) available for aspirin and ranitidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clinical aspects of gastric cytoprotection.
    Gastroenterologie clinique et biologique, 1985, Volume: 9, Issue:12 Pt 2

    Topics: Administration, Oral; Aluminum; Anti-Inflammatory Agents; Arthritis; Aspirin; Cell Survival; Clinical Trials as Topic; Dinoprostone; Double-Blind Method; Duodenum; Gastric Acid; Gastric Mucosa; Humans; Prostaglandins; Prostaglandins E; Ranitidine; Stomach Ulcer; Sucralfate

1985
Update in treatment of peptic ulcer disease.
    Missouri medicine, 1984, Volume: 81, Issue:11

    Topics: Adult; Aged; Alcohol Drinking; Aluminum; Antacids; Anti-Ulcer Agents; Aspirin; Bismuth; Cimetidine; Female; Humans; Male; Organometallic Compounds; Peptic Ulcer; Ranitidine; Recurrence; Smoking; Sucralfate; Vagotomy, Proximal Gastric

1984
A review of the animal pharmacology of ranitidine--a new, selective histamine H2-antagonist.
    Scandinavian journal of gastroenterology. Supplement, 1981, Volume: 69

    Topics: Administration, Oral; Animals; Aspirin; Bethanechol Compounds; Cimetidine; Dogs; Furans; Gastric Acid; Gastric Mucosa; Guinea Pigs; Heart Atria; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Injections, Intravenous; Male; Myocardial Contraction; Prostate; Ranitidine; Rats; Stomach Ulcer

1981
Histamine H2-antagonists--past, present and future.
    Journal of clinical gastroenterology, 1983, Volume: 5 Suppl 1

    Topics: Animals; Aspirin; Burimamide; Chemical Phenomena; Chemistry; Cimetidine; Dogs; Furans; Gastric Acid; Guanidines; Guinea Pigs; Half-Life; Histamine H2 Antagonists; Humans; Imidazoles; Methylamines; Ranitidine; Rats; Stomach; Thiazoles; Triazoles

1983
Prevention and treatment of nonsteroidal anti-inflammatory drug-induced gastropathy.
    Southern medical journal, 1995, Volume: 88, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Gastric Mucosa; Histamine H2 Antagonists; Humans; Misoprostol; Peptic Ulcer; Ranitidine; Risk Factors

1995
Nonsteroidal antiinflammatory drug-induced colonic stricture. An unusual cause of large bowel obstruction and perforation.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colon; Colonic Diseases; Delayed-Action Preparations; Dextropropoxyphene; Diclofenac; Drug Combinations; Drug Therapy, Combination; Emergencies; Female; Humans; Intestinal Obstruction; Intestinal Perforation; Middle Aged; Ranitidine

1995
The impact of nonsteroidal anti-inflammatory drug-induced gastropathy.
    The American journal of managed care, 2001, Volume: 7, Issue:1 Suppl

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Dyspepsia; Histamine H2 Antagonists; Humans; Misoprostol; Peptic Ulcer; Ranitidine

2001
The role of mucoregulatory agents after continence-preserving urinary diversion surgery.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2012, Mar-15, Volume: 69, Issue:6

    Topics: Acetylcysteine; Aspirin; Expectorants; Gastrointestinal Agents; Humans; Length of Stay; Mucus; Octreotide; Ranitidine; Urea; Urinary Diversion

2012

Trials

24 trial(s) available for aspirin and ranitidine

ArticleYear
Ranitidine: differential effects on gastric bleeding and mucosal damage induced by aspirin.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:6

    Topics: Adult; Aspirin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Hemostasis, Endoscopic; Humans; Male; Peptic Ulcer Hemorrhage; Ranitidine; Stomach Ulcer

1992
[75 mg roxatidine nocte protects human gastric mucosa against 300 mg acetylsalicylic acid nocte].
    Zeitschrift fur Gastroenterologie, 1991, Volume: 29, Issue:11

    Topics: Adult; Aspirin; Drug Administration Schedule; Drug Therapy, Combination; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Peptic Ulcer; Ranitidine

1991
[Protection from gastroduodenal adverse effects of acetylsalicylic acid with ranitidine. An endoscopic controlled double-blind study of healthy subjects].
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:6

    Topics: Adult; Aspirin; Double-Blind Method; Endoscopy, Gastrointestinal; Humans; Male; Peptic Ulcer; Ranitidine

1991
Aspirin concurrently administered with ranitidine does not delay healing of duodenal ulcer.
    Australian and New Zealand journal of medicine, 1990, Volume: 20, Issue:3

    Topics: Adult; Aspirin; Drug Therapy, Combination; Duodenal Ulcer; Duodenoscopy; Female; Humans; Male; Ranitidine

1990
[Effect of somatostatin and ranitidine in acute hemorrhage of the upper digestive tract].
    Acta gastroenterologica Latinoamericana, 1989, Volume: 19, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Female; Gastritis; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Peptic Ulcer; Ranitidine; Somatostatin

1989
Enhanced gastric mucosal bleeding with doses of aspirin used for prophylaxis and its reduction by ranitidine.
    British journal of clinical pharmacology, 1989, Volume: 28, Issue:5

    Topics: Adult; Aspirin; Female; Gastric Acid; Gastrointestinal Hemorrhage; Humans; Male; Ranitidine

1989
[Ranitidine protects the human stomach and duodenal mucosa against low-dose acetylsalicylic acid].
    Zeitschrift fur Gastroenterologie, 1989, Volume: 27, Issue:12

    Topics: Adult; Aspirin; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Male; Randomized Controlled Trials as Topic; Ranitidine

1989
[Gastroduodenal lesions in rheumatoid arthritis. Evaluation and treatment].
    Acta gastroenterologica Latinoamericana, 1988, Volume: 18, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Female; Gastric Mucosa; Humans; Male; Middle Aged; Peptic Ulcer; Prospective Studies; Random Allocation; Ranitidine

1988
[Acute injury to the gastric mucosa by acetylsalicylic acid. A comparative endoscopic study in man with oral prostaglandin analogs, omeprazole and ranitidine].
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:2

    Topics: Adult; Alprostadil; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Clinical Trials as Topic; Double-Blind Method; Gastric Mucosa; Gastroscopy; Humans; Misoprostol; Omeprazole; Prostaglandins E; Prostaglandins, Synthetic; Random Allocation; Ranitidine; Rioprostil; Stomach Ulcer

1986
[Stomach tolerance of nonsteroidal antirheumatic drugs: comparative endoscopic study].
    Zeitschrift fur Rheumatologie, 1987, Volume: 46 Suppl 1

    Topics: Adult; Alprostadil; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Gastroscopy; Humans; Indomethacin; Misoprostol; Omeprazole; Prostaglandins E; Ranitidine; Rioprostil; Stomach Ulcer

1987
Reduction of aspirin-induced gastroduodenal mucosal damage with ranitidine.
    Journal of clinical gastroenterology, 1986, Volume: 8, Issue:3 Pt 2

    Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Gastric Mucosa; Gastroscopy; Humans; Intestinal Mucosa; Male; Random Allocation; Ranitidine; Time Factors

1986
Effect of ranitidine on the absorption of aspirin.
    Digestion, 1987, Volume: 37, Issue:3

    Topics: Adult; Aspirin; Biological Availability; Double-Blind Method; Half-Life; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Male; Ranitidine

1987
Day and night aspirin-induced gastric mucosal damage and protection by ranitidine in man.
    Chronobiology international, 1987, Volume: 4, Issue:1

    Topics: Adult; Aspirin; Circadian Rhythm; Gastric Acid; Gastric Mucosa; Humans; Male; Ranitidine

1987
Ranitidine protects against gastroduodenal mucosal damage associated with chronic aspirin therapy.
    Archives of internal medicine, 1987, Volume: 147, Issue:12

    Topics: Adolescent; Adult; Aspirin; Duodenum; Gastric Mucosa; Gastrointestinal Diseases; Humans; Intestinal Mucosa; Male; Middle Aged; Ranitidine; Time Factors

1987
Clinical aspects of gastric cytoprotection.
    Gastroenterologie clinique et biologique, 1985, Volume: 9, Issue:12 Pt 2

    Topics: Administration, Oral; Aluminum; Anti-Inflammatory Agents; Arthritis; Aspirin; Cell Survival; Clinical Trials as Topic; Dinoprostone; Double-Blind Method; Duodenum; Gastric Acid; Gastric Mucosa; Humans; Prostaglandins; Prostaglandins E; Ranitidine; Stomach Ulcer; Sucralfate

1985
Ranitidine in the treatment of gastric ulceration.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1982, Jan-30, Volume: 61, Issue:5

    Topics: Aged; Alcohol Drinking; Antacids; Anti-Ulcer Agents; Aspirin; Cimetidine; Clinical Trials as Topic; Female; Furans; Humans; Male; Middle Aged; Random Allocation; Ranitidine; Smoking; Stomach Ulcer; Time Factors

1982
Ranitidine bismuth citrate and aspirin-induced gastric mucosal injury.
    Alimentary pharmacology & therapeutics, 1993, Volume: 7, Issue:5

    Topics: Adult; Aspirin; Bismuth; Citrates; Double-Blind Method; Duodenum; Gastric Mucosa; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Ranitidine

1993
[Circadian aspects of acetylsalicylic acid induced injury and protective effect of ranitidine on the the upper gastrointestinal tract].
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:8

    Topics: Adult; Aspirin; Circadian Rhythm; Double-Blind Method; Gastric Mucosa; Gastrointestinal Diseases; Humans; Intestinal Mucosa; Ranitidine

1994
[Studies on the protective effect of lansoprazole on human gastric mucosa against low-dose acetylsalicylic acid. An endoscopic controlled double-blind study].
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Aspirin; Double-Blind Method; Duodenoscopy; Gastroscopy; Histamine H2 Antagonists; Humans; Lansoprazole; Omeprazole; Peptic Ulcer; Platelet Aggregation Inhibitors; Ranitidine

1997
[The action of the proton pump inhibitor pantoprazol against acetylsalicylic acid-induced gastroduodenopathy in comparison to ranitidine. An endoscopic controlled, double blind comparison].
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Cyclooxygenase Inhibitors; Double-Blind Method; Endoscopy, Gastrointestinal; Enzyme Inhibitors; Humans; Male; Omeprazole; Pantoprazole; Peptic Ulcer; Proton Pump Inhibitors; Ranitidine; Sulfoxides

1998
Reducing mucus production after urinary reconstruction: a prospective randomized trial.
    The Journal of urology, 2001, Volume: 165, Issue:5

    Topics: Acetylcysteine; Administration, Intravesical; Administration, Oral; Aspirin; Cross-Over Studies; Double-Blind Method; Humans; Ileum; Intestinal Mucosa; Mucins; Mucus; Prospective Studies; Quality of Life; Ranitidine; Surveys and Questionnaires; Urinary Bladder; Urinary Diversion; Viscosity

2001
Effect of ranitidine on the antiplatelet effects of aspirin in healthy human subjects.
    The American journal of cardiology, 2007, Jan-01, Volume: 99, Issue:1

    Topics: Adult; Aspirin; Blood Platelets; Drug Synergism; Drug Therapy, Combination; Histamine H2 Antagonists; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Ranitidine

2007
Comparative study of therapeutic effects of PPI and H2RA on ulcers during continuous aspirin therapy.
    World journal of gastroenterology, 2010, Nov-14, Volume: 16, Issue:42

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Drug Therapy, Combination; Endoscopy; Famotidine; Histamine H2 Antagonists; Humans; Lansoprazole; Male; Middle Aged; Peptic Ulcer; Prospective Studies; Proton Pump Inhibitors; Ranitidine; Treatment Outcome; Wound Healing

2010
Doubling the dose of clopidogrel restores the loss of antiplatelet effect induced by esomeprazole.
    Thrombosis research, 2011, Volume: 128, Issue:5

    Topics: Aged; Anti-Ulcer Agents; Aspirin; Clopidogrel; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Esomeprazole; Female; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Function Tests; Ranitidine; Ticlopidine

2011

Other Studies

68 other study(ies) available for aspirin and ranitidine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
    International journal of pharmaceutics, 2003, Sep-16, Volume: 263, Issue:1-2

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Polyfluorinated salicylic acid derivatives as analogs of known drugs: Synthesis, molecular docking and biological evaluation.
    Bioorganic & medicinal chemistry, 2017, 01-01, Volume: 25, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Edema; Female; Halogenation; Male; Molecular Docking Simulation; Rats, Sprague-Dawley; Rats, Wistar; Salicylates; Sheep

2017
Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies.
    European journal of medicinal chemistry, 2020, Oct-15, Volume: 204

    Topics: Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Design; Enzyme Inhibitors; Humans; Hydrazones; Hypersensitivity; Lung; Male; Mice

2020
Ranitidine, aspirin, food, and the stomach.
    BMJ (Clinical research ed.), 1992, Feb-29, Volume: 304, Issue:6826

    Topics: Administration, Oral; Adult; Aspirin; Dose-Response Relationship, Drug; Female; Food; Gastric Mucosa; Humans; Male; Ranitidine; Stomach Diseases; Time Factors

1992
Gastroprotective and ulcer healing profile of the mast cell stabilizer quazolast in rats.
    Agents and actions, 1991, Volume: 33, Issue:3-4

    Topics: Acetates; Animals; Anti-Ulcer Agents; Aspirin; Gastric Acid; Gastric Mucosa; Histamine H1 Antagonists; Indomethacin; Male; Mast Cells; Quinolines; Ranitidine; Rats; Rats, Inbred Strains; Stomach Ulcer

1991
Aspirin concurrently administered with ranitidine does not delay healing of duodenal ulcer.
    Australian and New Zealand journal of medicine, 1991, Volume: 21, Issue:1

    Topics: Aspirin; Duodenal Ulcer; Humans; Ranitidine; Statistics as Topic

1991
Ethical aspects of a study of the effects of aspirin on the healing of duodenal ulcer.
    Australian and New Zealand journal of medicine, 1991, Volume: 21, Issue:1

    Topics: Aspirin; Duodenal Ulcer; Ethics, Medical; Humans; Ranitidine; Wound Healing

1991
Role of intragastric pH in cytoprotection by antacids in rats.
    European journal of pharmacology, 1990, Feb-06, Volume: 176, Issue:2

    Topics: Aluminum Hydroxide; Animals; Antacids; Aspirin; Dinoprostone; Drug Combinations; Ethanol; Female; Gastric Acid; Gastric Mucosa; Histamine; Hydrogen-Ion Concentration; Magnesium Hydroxide; Male; Ranitidine; Rats; Rats, Inbred Strains

1990
Ranitidine maintenance treatment of non-steroidal anti-inflammatory drug-induced duodenal ulceration.
    Alimentary pharmacology & therapeutics, 1989, Volume: 3, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Duodenal Ulcer; Duodenum; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Ranitidine; Recurrence; Risk Factors

1989
Effect of BMY-25368, a potent and long-acting histamine H2-receptor antagonist, on gastric secretion and aspirin-induced gastric lesions in the dog.
    Alimentary pharmacology & therapeutics, 1989, Volume: 3, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Bethanechol Compounds; Dogs; Dose-Response Relationship, Drug; Female; Food; Gastric Acid; Histamine H2 Antagonists; Pentagastrin; Piperidines; Ranitidine; Stomach Ulcer

1989
Prophylaxis of aspirin-induced gastric mucosal bleeding with ranitidine.
    Alimentary pharmacology & therapeutics, 1988, Volume: 2, Issue:3

    Topics: Adult; Aspirin; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Male; Ranitidine

1988
AM and PM measurement of gastric potential difference and prostacyclin production in humans: effects of ranitidine.
    Chronobiology international, 1988, Volume: 5, Issue:4

    Topics: Adult; Aspirin; Circadian Rhythm; Epoprostenol; Gastric Mucosa; Humans; Male; Membrane Potentials; Ranitidine; Reference Values

1988
Strategies for preventing aspirin-induced gastric bleeding.
    Scandinavian journal of gastroenterology. Supplement, 1986, Volume: 125

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cattle; Enprostil; Fatty Acids, Essential; Fatty Acids, Unsaturated; Female; gamma-Linolenic Acid; Gastrointestinal Hemorrhage; Humans; Linoleic Acid; Linoleic Acids; Lysine; Male; Milk; Oenothera biennis; Plant Oils; Prostaglandins E, Synthetic; Ranitidine

1986
Selective gastric antilesion properties of rioprostil, a prostaglandin E1 analog, in rats and dogs.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Dogs; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Acid; Gastric Mucosa; Male; Prostaglandins E; Prostaglandins E, Synthetic; Ranitidine; Rats; Rats, Inbred Strains; Rioprostil

1987
Effect of non-steroidal anti-inflammatory drugs and prostaglandins on the permeability of the human small intestine.
    Gut, 1986, Volume: 27, Issue:11

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Humans; Ibuprofen; Indomethacin; Intestine, Small; Permeability; Prostaglandins E; Ranitidine

1986
Hexaprazol antagonism to gastric electrical potential fall by acetylsalicylic acid in rat.
    Drugs under experimental and clinical research, 1985, Volume: 11, Issue:10

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Carbenoxolone; Cimetidine; Electric Stimulation; Female; Membrane Potentials; Piperazines; Ranitidine; Rats; Rats, Inbred Strains; Stomach

1985
S.E.M. study II: Protective effect of ranitidine against gastric and duodenal lesions induced by non-steroidal anti-inflammatory drugs.
    International journal of tissue reactions, 1986, Volume: 8, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Aspirin; Duodenal Ulcer; Endoscopy; Female; Humans; Male; Microscopy, Electron, Scanning; Middle Aged; Piroxicam; Ranitidine; Stomach Ulcer; Thiazines; Time Factors

1986
Comparison of the gastric cytoprotective properties of atropine, ranitidine and PGE2 in rats.
    European journal of pharmacology, 1984, Oct-30, Volume: 106, Issue:1

    Topics: Animals; Aspirin; Atropine; Dinoprostone; Ethanol; Female; Gastric Acid; Neostigmine; Parasympathomimetics; Prostaglandins E; Ranitidine; Rats; Rats, Inbred Strains; Stomach Ulcer

1984
Gastric cytoprotection by prostaglandins, ranitidine, and probanthine in rats. Role of endogenous prostaglandins.
    Scandinavian journal of gastroenterology, 1981, Volume: 16, Issue:1

    Topics: Animals; Aspirin; Epoprostenol; Furans; Gastric Juice; Gastric Mucosa; Histamine H2 Antagonists; Hydrochloric Acid; Propantheline; Prostaglandins E; Prostaglandins F; Ranitidine; Rats; Stomach Ulcer

1981
H2-receptor antagonists protect against aspirin-induced gastric lesions in the rat.
    Agents and actions, 1981, Volume: 11, Issue:1-2

    Topics: Animals; Aspirin; Cimetidine; Female; Furans; Gastric Mucosa; Histamine H2 Antagonists; Pyrilamine; Ranitidine; Rats; Stomach Ulcer

1981
Aspirin-induced gastric ulcers in cats. Prevention by prostacyclin.
    Digestive diseases and sciences, 1981, Volume: 26, Issue:11

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Cats; Epoprostenol; Furans; Gastric Acid; Histamine; Histamine H2 Antagonists; Hormones; Hydrochloric Acid; Pentagastrin; Prostaglandin Antagonists; Prostaglandins; Ranitidine; Stomach Ulcer

1981
[Effects of ranitidine, a new histamine H2-receptor antagonist, on histamine- and aspirin-induced gastric ulcers in rats and dogs (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1981, Volume: 78, Issue:6

    Topics: Animals; Aspirin; Dogs; Dose-Response Relationship, Drug; Female; Furans; Histamine; Histamine H2 Antagonists; Male; Ranitidine; Rats; Rats, Inbred Strains; Stomach Ulcer

1981
Comparison of prostaglandin E2 and ranitidine in prevention of gastric bleeding by aspirin in man.
    Gut, 1983, Volume: 24, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Aspirin; Dinoprostone; DNA; Furans; Gastric Mucosa; Histamine H2 Antagonists; Humans; Male; Peptic Ulcer Hemorrhage; Prostaglandins E; Ranitidine; Stomach Ulcer

1983
Studies of the factors that influence acetylsalicylic acid-induced gastric damage in stressed rats.
    Pharmacological research communications, 1983, Volume: 15, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Female; Furans; Gastric Mucosa; Histamine H2 Antagonists; Humans; Prostaglandins; Ranitidine; Rats; Rats, Inbred Strains; Restraint, Physical; Stomach Ulcer; Stress, Psychological

1983
JB-9322, a new selective histamine H2-receptor antagonist with potent gastric mucosal protective properties.
    British journal of pharmacology, 1995, Volume: 115, Issue:1

    Topics: Animals; Aspirin; Ethanol; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Male; Muscarinic Antagonists; Piperidines; Ranitidine; Rats; Rats, Wistar; Stomach Diseases

1995
Effects of nonsteroidal antiinflammatory drugs on ulcerogenesis and gastric secretion in pylorus-ligated rat.
    Digestive diseases and sciences, 1995, Volume: 40, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Gastric Acid; Gastric Mucosa; Histamine; Ibuprofen; Indomethacin; Ligation; Male; Pepsinogens; Pylorus; Ranitidine; Rats; Rats, Sprague-Dawley; Salicylates; Stomach Ulcer

1995
Inhibition of rabbit duodenal bicarbonate secretion by ulcerogenic agents: histamine-dependent and -independent effects.
    Gastroenterology, 1998, Volume: 114, Issue:3

    Topics: Animals; Aspirin; Bicarbonates; Dinoprostone; Duodenum; Electric Stimulation; Ethanol; Histamine; Histamine Release; Male; Rabbits; Ranitidine; Tetrodotoxin

1998
Pentagastrin gastroprotection against acid is related to H2 receptor activation but not acid secretion.
    Gut, 1998, Volume: 43, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Gastric Acid; Gastric Mucosa; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Male; Omeprazole; Pentagastrin; Perfusion; Pyrilamine; Ranitidine; Rats; Rats, Sprague-Dawley; Stomach Ulcer

1998
Effects of different antisecretory drugs on gastric potential difference in the rat: comparison with sucralfate.
    Pharmacological research, 1998, Volume: 38, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Aspirin; Drug Interactions; Gastric Acid; Lansoprazole; Male; Nizatidine; Omeprazole; Proton Pump Inhibitors; Ranitidine; Rats; Rats, Wistar; Sucralfate

1998
Inhibitory effects of H2-receptor antagonists on platelet function in vitro.
    Human & experimental toxicology, 1999, Volume: 18, Issue:8

    Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cimetidine; Collagen; Famotidine; Female; Heterocyclic Compounds, 1-Ring; Histamine H2 Antagonists; Humans; In Vitro Techniques; Male; Middle Aged; P-Selectin; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Ranitidine; Structure-Activity Relationship

1999
Low dose aspirin as prophylaxis against renal-vein thrombosis in renal-transplant recipients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2000, Volume: 15, Issue:11

    Topics: Adult; Aged; Aspirin; Cadaver; Cyclosporine; Databases as Topic; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Immunosuppressive Agents; Incidence; Kidney Transplantation; Living Donors; Middle Aged; Postoperative Complications; Ranitidine; Renal Veins; Retrospective Studies; Time Factors; Tissue Donors; Treatment Failure; Venous Thrombosis

2000
Current approaches to reducing gastrointestinal toxicity of low-dose aspirin.
    The American journal of medicine, 2001, Jan-08, Volume: 110, Issue:1A

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Misoprostol; Omeprazole; Peptic Ulcer; Ranitidine

2001
pH-Metric log K calculations of famotidine, naproxen, nizatidine, ranitidine and salicylic acid.
    Farmaco (Societa chimica italiana : 1989), 2001, Volume: 56, Issue:9

    Topics: Anti-Inflammatory Agents; Anti-Ulcer Agents; Aspirin; Chromatography, High Pressure Liquid; Computers; Famotidine; Hydrogen-Ion Concentration; Naproxen; Nizatidine; Ranitidine; Structure-Activity Relationship

2001
Gastroprotective activity of solidagenone on experimentally-induced gastric lesions in rats.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Drug; Furans; Male; Naphthalenes; Omeprazole; Ranitidine; Rats; Rats, Sprague-Dawley; Stomach Ulcer

2002
Gastroprotective activity of oleanolic acid derivatives on experimentally induced gastric lesions in rats and mice.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Drug; Ethanol; Hydrochloric Acid; Lansoprazole; Ligation; Male; Mice; Molecular Structure; Oleanolic Acid; Omeprazole; Phytotherapy; Pylorus; Ranitidine; Rats; Rats, Sprague-Dawley; Solanaceae; Stomach Ulcer; Toxicity Tests, Acute

2002
Ocular tilt reaction due to a mesencephalic lesion in juvenile polyarteritis nodosa.
    American journal of ophthalmology, 2003, Volume: 135, Issue:2

    Topics: Aspirin; Brain Diseases; Child, Preschool; Cyclophosphamide; Diplopia; Drug Therapy, Combination; Female; Head Movements; Humans; Kidney Diseases; Magnetic Resonance Imaging; Nystagmus, Pathologic; Polyarteritis Nodosa; Prednisolone; Radiography; Ranitidine; Saccades; Strabismus; Tegmentum Mesencephali

2003
The inhibition of gastric mucosal injury by Punicagranatum L. (pomegranate) methanolic extract.
    Journal of ethnopharmacology, 2005, Jan-04, Volume: 96, Issue:1-2

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Ethanol; Fruit; Gastric Mucosa; Lipid Peroxidation; Lythraceae; Male; Methanol; Phytotherapy; Plant Extracts; Ranitidine; Rats; Rats, Wistar; Stomach Ulcer

2005
Influence of gastric colonization with Candida albicans on ulcer healing in rats: effect of ranitidine, aspirin and probiotic therapy.
    Scandinavian journal of gastroenterology, 2005, Volume: 40, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Biopsy; Blood Flow Velocity; Candida albicans; Chronic Disease; Colony Count, Microbial; Cytokines; Disease Models, Animal; Electrophoresis, Agar Gel; Gastric Juice; Gastric Mucosa; Gastrins; Gene Expression Regulation; Lactobacillus acidophilus; Male; Microcirculation; Probiotics; Ranitidine; Rats; Rats, Wistar; RNA, Messenger; Stomach Ulcer

2005
Protective effect of Cissus quadrangularis on neutrophil mediated tissue injury induced by aspirin in rats.
    Journal of ethnopharmacology, 2006, Apr-06, Volume: 104, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Aspirin; Cissus; Dose-Response Relationship, Drug; Lipid Peroxidation; Male; Neutrophils; Phytotherapy; Plant Extracts; Ranitidine; Rats; Rats, Wistar; Stomach Ulcer

2006
ACEA (arachidonyl-2-chloroethylamide), the selective cannabinoid CB1 receptor agonist, protects against aspirin-induced gastric ulceration.
    Die Pharmazie, 2006, Volume: 61, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arachidonic Acids; Aspirin; Dose-Response Relationship, Drug; Gastric Mucosa; Ranitidine; Rats; Receptor, Cannabinoid, CB1; Stomach Ulcer

2006
Antiulcerogenic potential of Strychnos potatorum Linn seeds on aspirin plus pyloric ligation-induced ulcers in experimental rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2007, Volume: 14, Issue:5

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Aspirin; Female; Ligation; Male; Phytotherapy; Plant Extracts; Ranitidine; Rats; Rats, Wistar; Seeds; Stomach Ulcer; Strychnos

2007
Prophylactic use of gastro-protective agents in patients on low-dose aspirin.
    British journal of clinical pharmacology, 2008, Volume: 65, Issue:4

    Topics: Adult; Aged; Aspirin; Female; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Male; Middle Aged; Proton Pump Inhibitors; Ranitidine; Treatment Outcome

2008
Gastric protection and gastrointestinal bleeding with aspirin thromboprophylaxis in hip and knee joint replacements.
    Annals of the Royal College of Surgeons of England, 2008, Volume: 90, Issue:4

    Topics: Aged; Anti-Ulcer Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Aspirin; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Humans; Male; Platelet Aggregation Inhibitors; Ranitidine; Retrospective Studies; Risk Factors; Thromboembolism

2008
Drug-induced papuloerythroderma of Ofuji: comment.
    The Journal of dermatology, 2008, Volume: 35, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dermatitis, Exfoliative; Diuretics; Drug Eruptions; Furosemide; Humans; Lymphocyte Activation; Ranitidine

2008
Gastroprotective effect of earthworm paste (Lampito mauritii, Kinberg) on experimental gastric ulcer in rats.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Acid; Gastric Juice; Gastric Mucosa; Glycoproteins; Histamine H2 Antagonists; Hydrogen-Ion Concentration; India; Male; Medicine, East Asian Traditional; Oligochaeta; Pepsin A; Ranitidine; Rats; Stomach Ulcer

2010
Anti-inflammatory and anti-ulcer activity of the extract from Alhagi maurorum (camelthorn).
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:10

    Topics: alpha-L-Fucosidase; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Aspirin; Eating; Egypt; Fabaceae; Gas Chromatography-Mass Spectrometry; Gastric Mucosa; Glutathione; Lipids; Liver; Liver Function Tests; Male; Plant Extracts; Ranitidine; Rats; Rats, Sprague-Dawley; Stomach Ulcer

2010
Gastroprotective effect of standardized leaf extract from Argyreia speciosa on experimental gastric ulcers in rats.
    Journal of ethnopharmacology, 2011, Sep-01, Volume: 137, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Butanols; Catalase; Convolvulaceae; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Free Radical Scavengers; Gastric Juice; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Lipid Peroxidation; Male; Mice; Mucus; Plant Extracts; Plant Leaves; Ranitidine; Rats; Rats, Sprague-Dawley; Solvents; Stomach Ulcer; Superoxide Dismutase

2011
Conservative therapy is associated with worse clinical features and biochemical derangements than renal replacement therapy: a retrospective study in Kumasi, Ghana.
    BMC nephrology, 2022, 10-26, Volume: 23, Issue:1

    Topics: Adult; Aspirin; Bisoprolol; Conservative Treatment; Furosemide; Ghana; Humans; Irbesartan; Kidney Failure, Chronic; Lisinopril; Metformin; Middle Aged; Nifedipine; Ranitidine; Renal Replacement Therapy; Retrospective Studies; Sodium

2022
Detection and analysis of potential drug-drug interactions among patients admitted to the cardiac care unit in a tertiary care hospital.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:2

    Topics: Aspirin; Cardiovascular Diseases; Clopidogrel; Drug Interactions; Enoxaparin; Furosemide; Humans; Lisinopril; Ranitidine; Tertiary Care Centers

2023