aspirin has been researched along with prostaglandin d2 in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (16.22) | 18.7374 |
| 1990's | 22 (29.73) | 18.2507 |
| 2000's | 20 (27.03) | 29.6817 |
| 2010's | 18 (24.32) | 24.3611 |
| 2020's | 2 (2.70) | 2.80 |
| Authors | Studies |
|---|---|
| Bulbena, O; Gelpí, E; Montserrat, JM; Picado, C; Plaza, V; Prat, J; Ramis, I; Rosellò, J | 1 |
| Chamberlin, BA; Gage, DA; Kaiser, L; Lamb, VL; Tithof, PK; Watson, JT; Williams, JF | 1 |
| Coleman, RA; Head, SA; Poll, CT; Whelan, CJ | 1 |
| Bulbena, O; Gelpí, E; Picado, C; Ramis, I; Roselló-Catafau, J | 1 |
| Davies, BH; Pawlowicz, A; Williams, WR | 1 |
| Chakraborti, S; Gurtner, GH; Michael, JR | 1 |
| Adkinson, NF; Brown, MS; Kagey-Sobotka, A; Lichtenstein, LM; Naclerio, RM; Norman, PS; Peters, SP; Proud, D | 1 |
| Casteleijn, E; Kamps, JA; Koster, JF; Kuiper, J; Van Berkel, TJ; Van Rooij, HC | 2 |
| Blockmans, D; Bounameaux, H; Vermylen, J; Verstraete, M | 1 |
| Bertelé, V; Castagnoli, MN; Cerletti, C; de Gaetano, G; Rajtar, G | 1 |
| Newman, JH; Sheller, JR | 1 |
| Agostini, MD; Borda, ES; Gimeno, MF; Peredo, H | 1 |
| Haak, A; Kootte, AM; Roberts, LJ | 1 |
| Abelson, MB; Butrus, SI; Weston, JH | 1 |
| Toda, N | 1 |
| Smith, JB | 1 |
| Bembry, J; McCarron, RM; Roberts, LJ; Spatz, M; Stanimirovic, D; Uematsu, S | 1 |
| Casolaro, V; de Paulis, A; Guidi, G; Marino, O; Marone, G; Meliota, S; Patella, V | 1 |
| Hespeling, U; Jungermann, K; Püschel, GP | 1 |
| Butterfield, JH; Kao, PC; Klee, GC; Yocum, MW | 1 |
| Esteva, F; Lanas, AI; Nerín, J; Sáinz, R | 1 |
| Awad, JA; Minton, TA; Morrow, JD; Roberts, LJ | 1 |
| Badia, P; Boecker, MR; Murphy, PJ; Myers, BL; Wright, KP | 1 |
| Inase, N; Lazarus, SC; Levine, TM | 1 |
| Harada, T; Juhn, SK; Kim, Y; Sakakura, Y | 1 |
| Faili, A; Hatmi, M; Randon, J; Vargaftig, BB | 1 |
| Minton, TA; Morrow, JD | 1 |
| Daugschies, A | 1 |
| Goto, H; Hayakawa, T; Kanamori, S; Ozawa, T; Shimomura, Y; Sugiyama, S | 1 |
| Dahlén, B; Dahlén, SE; Kumlin, M; O'Sullivan, S | 1 |
| Crews, BC; Garner, C; Kalgutkar, AS; Marnett, LJ; Rowlinson, SW; Seibert, K | 1 |
| Cmiel, A; Dworski, R; Mastalerz, L; Nizankowska, E; Oates, JA; Prokop, A; Sheller, JR; Szczeklik, A | 1 |
| Abbracchio, MP; Bonazzi, A; Brambilla, R; Burnstock, G; Cattabeni, F; Ceruti, S | 1 |
| Iwaszkiewicz, J; Kaliner, MA; Kornatowski, T; Kowalski, ML; Pawliczak, R; Poniatowska, M; Siuda, K; Wozniak, J | 1 |
| Bochenek, G; Mejza, F; Nagraba, K; Nizankowska, E; Swierczynska, M; Szczeklik, A | 1 |
| Akiyama, K; Higashi, N; Mita, H; Osame, M; Taniguchi, M | 1 |
| Duszenko, M; Fukuzumi, S; Kabututu, Z; Kubata, BK; Lazarus, M; Martin, SK; Maruyama, T; Munday, CJ; Nozaki, T; Ohkubo, K; Urade, Y | 1 |
| Bochenek, G; Nagraba, K; Nizankowska, E; Szczeklik, A | 1 |
| Pierzchalska, M; Sanak, M; Soja, J; Szabó, Z; Szczeklik, A | 1 |
| Ago, T; Iida, M; Iwase, M; Kitazono, T; Nakamura, U; Ueta, M; Wakisaka, M; Yoshinari, M | 1 |
| Alegret, M; Bermúdez, I; Laguna, JC; Llaverias, G; Sanchez, RM; Vázquez-Carrera, M; Viñals, M | 1 |
| Hsieh, PW; Wang, TW; Wang, WY; Wu, CC; Wu, YC | 1 |
| Cheng, K; Gottesdiener, K; Lai, E; Metters, K; O'Neill, G; Sturino, C; Wang, Z; Waters, MG; Wright, SD; Wu, KK; Wu, TJ | 1 |
| Arai, I; Futaki, N; Hashimoto, Y; Honma, Y; Nakaike, S; Sugimoto, M | 1 |
| Kamanna, VS; Kashyap, ML; Liu, P; Meyers, CD | 1 |
| Lau, HY; Leung, PS; Wang, XS; Wu, AY | 1 |
| Nizankowska-Mogielnicka, E; Pierzchalska, M; Sanak, M; Soja, J; Szabó, Z; Szczeklik, A; Woś, M | 1 |
| Boucher, W; Kempuraj, D; Papaliodis, D; Theoharides, TC | 1 |
| Butterfield, JH; Weiler, CR | 1 |
| Haruna, S; Moriyama, H; Otori, N; Yoshikawa, M; Yoshimura, T | 1 |
| Asanuma, M; Miyazaki, I; Miyoshi, K; Ogawa, N; Tsuji, T | 1 |
| Dercho, RA; Di Francesco, A; Di Francesco, L; Dovizio, M; Evangelista, V; Pandolfi, A; Patrignani, P; Piccoli, A; Salvatore, T; Seta, F; Totani, L | 1 |
| Butterfield, JH | 1 |
| Chowdhury, AA; Hossain, MS; Jisaka, M; Nagaya, T; Nishimura, K; Rahman, MS; Shono, F; Yokota, K | 1 |
| Cefali, G; Gilmer, JF; Harmon, S; Jones, M; Kerins, DM; Ledwidge, MT; O'Connell, D; Ryan, F | 1 |
| Dejucq-Rainsford, N; Desdoits-Lethimonier, C; Jégou, B; Kristensen, DM; Le Fol, V; Leffers, H; Lesné, L | 1 |
| Chiamvimonvat, N; Hammock, BD; Li, N; Liu, JY; Qiu, H; Wei, D; Yamoah, EN | 1 |
| Carlson, LM; Idborg, H; Jakobsson, PJ; Kogner, P; Rasmuson, A; Segerström, L; Sveinbjörnsson, B | 1 |
| Aldrovandi, M; Clark, SR; Collins, PW; Hammond, VJ; Hornshaw, M; Marnett, LJ; Murphy, RC; O'Donnell, VB; Podmore, H; Slatter, DA | 1 |
| Ding, G; Liu, Y; Tang, J; Tang, Z; Wang, S; Wu, T; Xiong, J; Zhang, C | 1 |
| Bochenek, G; Ćmiel, A; Gielicz, A; Niżankowska-Mogilnicka, E; Plutecka, H; Sanak, M; Stręk, P; Świerczyńska-Krępa, M; Szczeklik, A | 1 |
| Borish, L; Liu, L; Negri, J; Payne, SC; Steinke, JW | 1 |
| Barreda, DR; Befus, AD; Bredo, G; Cameron, L; Campos-Alberto, E; Moon, TC; Puttagunta, L; Rieger, AM; Yoshimura, T | 1 |
| Bachert, C; De Ruyck, N; Derycke, L; Holtappels, G; Niżankowska-Mogilnicka, E; Pérez-Novo, CA; Pezato, R; Sanak, M; Świerczyńska-Krępa, M; Van Crombruggen, K | 1 |
| Boyce, JA; Laidlaw, TM | 1 |
| Bieńkiewicz, B; Kowalski, ML; Kurowski, M; Lewandowska-Polak, A; Makowska, JS; Olszewska-Ziąber, A; Rotkiewicz, A; Woźniakowski, B | 1 |
| Baker, MG; Borish, L; Feng, X; Negri, J; Payne, SC; Ramsden, MK; Steinke, JW | 1 |
| Bae, DJ; Chang, HS; Choi, JS; Hwang, HG; Lee, HJ; Lee, JU; Park, CS; Park, JS; Son, JH | 1 |
| Alfonso-Carrillo, C; Bobolea, I; Cabañas, R; Del Pozo, V; Fiandor, A; Heredia Revuelto, R; Quirce, S; Salcedo, MÁ; Sanz, V | 1 |
| Butterfield, J; Castells, M | 1 |
| Borish, L | 1 |
| Asaka, D; Fujieda, S; Haruna, S; Hirota, T; Hizawa, N; Ishitoya, J; Isogai, S; Kojima, H; Mitsui, C; Morikawa, T; Nakayama, T; Ninomiya, T; Okano, M; Sakashita, M; Takeno, S; Tamari, M; Tanaka, Y; Taniguchi, M; Yoshida, N; Yoshikawa, M | 1 |
| Fukutomi, Y; Hamada, Y; Hasegawa, Y; Hashimoto, N; Hayashi, H; Izuhara, K; Kajiwara, K; Kamide, Y; Mitsui, C; Nakamura, Y; Sekiya, K; Taniguchi, M; Tomita, Y; Tsuburai, T; Wakahara, K; Watai, K | 1 |
2 review(s) available for aspirin and prostaglandin d2
| Article | Year |
|---|---|
Arachidonic acid metabolites in the healthy and diseased lung.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Bronchitis; Dinoprost; Dinoprostone; Epoprostenol; Humans; Leukotriene B4; Lung; Lung Diseases; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostaglandins G; Prostaglandins H; Pulmonary Circulation; Pulmonary Ventilation; SRS-A | 1984 |
Mast Cell Activation Syndrome and Mastocytosis: Initial Treatment Options and Long-Term Management.
Topics: Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cromolyn Sodium; Disease Management; Glucocorticoids; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyurea; Interleukin-6; Leukotriene Antagonists; Leukotriene E4; Mastocytosis; Omalizumab; Prostaglandin D2; Tryptases | 2019 |
9 trial(s) available for aspirin and prostaglandin d2
| Article | Year |
|---|---|
Release of peptide leukotriene into nasal secretions after local instillation of aspirin in aspirin-sensitive asthmatic patients.
Topics: Administration, Intranasal; Adult; Albumins; Aspirin; Asthma; Dinoprost; Dinoprostone; Drug Hypersensitivity; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotrienes; Male; Middle Aged; Nasal Mucosa; Prostaglandin D2 | 1992 |
Nonsteroidal anti-inflammatory drugs affect normal sleep patterns in humans.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Temperature Regulation; Dose-Response Relationship, Drug; Female; Humans; Ibuprofen; Male; Melatonin; Polysomnography; Prostaglandin D2; Reaction Time; Sleep Stages; Sleep, REM; Wakefulness | 1994 |
Increased urinary excretion of the prostaglandin D2 metabolite 9 alpha, 11 beta-prostaglandin F2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction.
Topics: Adult; Airway Obstruction; Allergens; Aspirin; Asthma; Bronchial Provocation Tests; Chromatography, High Pressure Liquid; Cross-Over Studies; Dinoprost; Double-Blind Method; Histamine; Humans; Immunoenzyme Techniques; Lysine; Mast Cells; Middle Aged; Prostaglandin D2 | 1996 |
Salmeterol prevents aspirin-induced attacks of asthma and interferes with eicosanoid metabolism.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Albuterol; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchodilator Agents; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method; Eicosanoids; Eosinophils; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Lysine; Male; Middle Aged; Placebos; Prostaglandin D2; Prostaglandins D; Salmeterol Xinafoate | 1998 |
Safety of a specific COX-2 inhibitor in aspirin-induced asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cross-Over Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Isoenzymes; Lactones; Leukotriene E4; Male; Membrane Proteins; Middle Aged; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Sulfones | 2001 |
Aspirin desensitization in patients with aspirin-induced and aspirin-tolerant asthma: a double-blind study.
Topics: Administration, Oral; Adult; Aged; Allergens; Aspirin; Asthma; Asthma, Aspirin-Induced; Chronic Disease; Desensitization, Immunologic; Dinoprost; Double-Blind Method; Eosinophils; Female; Follow-Up Studies; Humans; Leukotriene E4; Male; Middle Aged; Nasal Polyps; Pilot Projects; Prostaglandin D2; Rhinitis; Sinusitis; Spirometry; Treatment Outcome | 2014 |
Aspirin activation of eosinophils and mast cells: implications in the pathogenesis of aspirin-exacerbated respiratory disease.
Topics: Aspirin; Asthma, Aspirin-Induced; Calcium Signaling; Cyclooxygenase Inhibitors; Cysteine; Eosinophil-Derived Neurotoxin; Eosinophils; Female; Humans; Interferon-gamma; Leukotrienes; Male; Mast Cells; Prostaglandin D2 | 2014 |
Systemic expression of inflammatory mediators in patients with chronic rhinosinusitis and nasal polyps with and without Aspirin Exacerbated Respiratory Disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; Chronic Disease; Cytokines; Female; Humans; Immunoenzyme Techniques; Inflammation Mediators; Leukotriene E4; Male; Middle Aged; Nasal Polyps; Prostaglandin D2; Rhinitis; Single-Blind Method; Sinusitis; T-Lymphocyte Subsets | 2016 |
Omalizumab for Aspirin Hypersensitivity and Leukotriene Overproduction in Aspirin-exacerbated Respiratory Disease. A Randomized Controlled Trial.
Topics: Adult; Aged; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aspirin; Asthma, Aspirin-Induced; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Male; Middle Aged; Omalizumab; Prostaglandin D2; Young Adult | 2020 |
63 other study(ies) available for aspirin and prostaglandin d2
| Article | Year |
|---|---|
Dirofilaria immitis: do filarial cyclooxygenase products depress endothelium-dependent relaxation in the in vitro rat aorta?
Topics: Acetylcholine; Animals; Aorta, Thoracic; Aspirin; Dirofilaria immitis; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Male; Prostaglandin D2; Rats; Rats, Inbred Strains; Vasodilation | 1992 |
Prostaglandin (PG) modulation of bradykinin-induced hyperalgesia and oedema in the guinea-pig paw--effects of PGD2, PGE2 and PGI2.
Topics: Animals; Aspirin; Bradykinin; Dinoprostone; Edema; Epoprostenol; Female; Guinea Pigs; Pain; Prostaglandin D2; Prostaglandins; Sensory Thresholds | 1991 |
Recovery of nasal prostaglandin production after inhibition by aspirin.
Topics: Adult; Animals; Arachidonate Lipoxygenases; Aspirin; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; Nasal Mucosa; Prostaglandin D2; Prostaglandins; SRS-A; Time Factors | 1990 |
In vitro tests for the diagnosis of aspirin-sensitive asthma.
Topics: Adult; Aged; Aspirin; Asthma; beta-Thromboglobulin; Blood Platelets; Dinoprost; Dinoprostone; Drug Tolerance; Female; Humans; Luminescent Measurements; Male; Middle Aged; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases | 1990 |
Oxidant-mediated activation of phospholipase A2 in pulmonary endothelium.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Kinetics; Peroxides; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandin D2; Pulmonary Artery; tert-Butylhydroperoxide; Thromboxane B2; Vitamin E | 1989 |
Arachidonic acid metabolites during nasal challenge.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Female; Histamine; Humans; Male; Nasal Provocation Tests; Peptide Hydrolases; Premedication; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Rhinitis, Allergic, Seasonal; Sneezing; SRS-A; Thromboxanes | 1987 |
Prostaglandin D2 mediates the stimulation of glycogenolysis in the liver by phorbol ester.
Topics: Animals; Aspirin; Drug Synergism; Glucagon; Glucose; In Vitro Techniques; Liver; Liver Glycogen; Male; Prostaglandin D2; Prostaglandins D; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1988 |
Endotoxin stimulates glycogenolysis in the liver by means of intercellular communication.
Topics: Animals; Aspirin; Cell Communication; Endotoxins; Escherichia coli; Glucose; In Vitro Techniques; Kinetics; Lipopolysaccharides; Liver; Liver Glycogen; Male; Perfusion; Prostaglandin D2; Prostaglandins D; Rats; Rats, Inbred Strains | 1988 |
Heparin-induced thrombocytopenia platelet aggregation studies in the presence of heparin fractions or semi-synthetic analogues of various molecular weights and anticoagulant activities.
Topics: Adenosine; Aged; Aspirin; Epoprostenol; Heparin; Humans; In Vitro Techniques; Male; Molecular Weight; Platelet Aggregation; Prostaglandin D2; Prostaglandins D; Thrombocytopenia | 1986 |
Prostaglandins and human platelet aggregation. Implications for the anti-aggregating activity of thromboxane-synthase inhibitors.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Dinoprost; Dinoprostone; Drug Synergism; Humans; Imidazoles; Oxidoreductases; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostanoic Acids; Thromboxane B2; Thromboxane-A Synthase | 1985 |
Hypersensitivity to norepinephrine in vasa deferentia from diabetic rats. Possible participation of metabolic products of arachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Carbon Radioisotopes; Catechols; Diabetes Mellitus, Experimental; Indomethacin; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenoxybenzamine; Prostaglandin D2; Prostaglandins; Prostaglandins D; Rats; Rats, Inbred Strains; Vas Deferens | 1984 |
The flush syndrome: an expression of systemic mastocytosis with increased prostaglandin D2 production.
Topics: Adult; Aspirin; Erythema; Humans; Hypotension; Male; Prostaglandin D2; Prostaglandins; Prostaglandins D; Shock; Syndrome; Urticaria Pigmentosa | 1983 |
Aspirin therapy in vernal conjunctivitis.
Topics: Adolescent; Aspirin; Child; Conjunctivitis; Female; Histamine; Humans; Hypersensitivity; Male; Mast Cells; Prostaglandin D2; Prostaglandins D; Seasons; Urticaria Pigmentosa | 1983 |
Different responsiveness of a variety of isolated dog arteries to prostaglandin D2.
Topics: Animals; Arteries; Aspirin; Cerebral Arteries; Coronary Vessels; Dinoprost; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Female; Femoral Artery; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Polyphloretin Phosphate; Prostaglandin D2; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Renal Artery | 1982 |
Prostaglandins and platelet aggregation.
Topics: Alprostadil; Animals; Arteries; Aspirin; Blood Platelets; Cattle; Epoprostenol; Humans; Platelet Aggregation; Prostaglandin D2; Prostaglandins; Prostaglandins D; Prostaglandins E; Thromboxane B2 | 1981 |
Prostaglandin D2 and endothelin-1 induce the production of prostaglandin F2 alpha, 9 alpha, 11 beta-prostaglandin F2, prostaglandin E2, and thromboxane in capillary endothelium of human brain.
Topics: 1-Methyl-3-isobutylxanthine; Aspirin; Brain; Capillaries; Cells, Cultured; Dexamethasone; Dinoprost; Dinoprostone; Endothelins; Endothelium, Vascular; Humans; Indomethacin; Prostaglandin D2; Thromboxane B2 | 1993 |
Nimesulide, a sulfonanilide nonsteroidal anti-inflammatory drug, inhibits mediator release from human basophils and mast cells.
Topics: Adolescent; Adult; Alprostadil; Amino Acid Sequence; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basophils; Bryostatins; Calcimycin; Colforsin; Complement C5a; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Lactones; Leukotriene C4; Lung; Macrolides; Mast Cells; Middle Aged; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandin D2; Skin; Sulfonamides; Tetradecanoylphorbol Acetate | 1993 |
Feedback-inhibition of glucagon-stimulated glycogenolysis in hepatocyte/Kupffer cell cocultures by glucagon-elicited prostaglandin production in Kupffer cells.
Topics: Animals; Aspirin; Cells, Cultured; Coculture Techniques; Dinoprost; Dinoprostone; Feedback; Glucagon; Kupffer Cells; Liver; Liver Glycogen; Male; Prostaglandin D2; Rats; Rats, Wistar | 1995 |
Aspirin idiosyncrasy in systemic mast cell disease: a new look at mediator release during aspirin desensitization.
Topics: Adult; Aspirin; Calcitonin; Calcitonin Gene-Related Peptide; Chymases; Desensitization, Immunologic; Epinephrine; Humans; Hypotension; Imidazoles; Inflammation Mediators; Male; Mastocytosis; Prostaglandin D2; Serine Endopeptidases; Tryptases | 1995 |
Non-steroidal anti-inflammatory drugs and prostaglandin effects on pepsinogen secretion by dispersed human peptic cells.
Topics: Acetylcholine; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colforsin; Dinoprostone; Drug Synergism; Female; Gastric Mucosa; Histamine; Humans; Ibuprofen; In Vitro Techniques; Male; Middle Aged; Pepsinogens; Prostaglandin D2; Stimulation, Chemical | 1995 |
Release of markedly increased quantities of prostaglandin D2 from the skin in vivo in humans following the application of sorbic acid.
Topics: Administration, Topical; Adult; Aspirin; Dinoprost; Dose-Response Relationship, Drug; Humans; Middle Aged; Prostaglandin D2; Skin; Sorbic Acid; Vasodilation | 1994 |
Mitogen-inducible prostaglandin G/H synthase is expressed in canine mastocytoma cells.
Topics: Animals; Aspirin; Cycloheximide; Dactinomycin; Dexamethasone; Dogs; Gene Expression; Mast Cells; Mast-Cell Sarcoma; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Arachidonic acid metabolism by isolated and cultured middle ear epithelial cells from the chinchilla.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Aspirin; Cell Separation; Cells, Cultured; Chinchilla; Dinoprost; Dinoprostone; Ear, Middle; Epithelial Cells; Epithelium; Indomethacin; Prostaglandin D2; Thromboxane B2; Time Factors; Tritium | 1993 |
Reduction by arachidonic acid of prostaglandin I2-induced cyclic AMP formation. Involvement of prostaglandins E2 and F2 alpha.
Topics: Arachidonic Acid; Aspirin; Blood Platelets; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; Drug Interactions; Epoprostenol; Humans; Pentanoic Acids; Platelet Aggregation; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Pyridines; Thromboxane B2 | 1993 |
Improved assay for the quantification of 11-dehydrothromboxane B2 by gas chromatography-mass spectrometry.
Topics: Aspirin; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Prostaglandin D2; Solvents; Thromboxane B2 | 1993 |
Oesophagostomum dentatum: population dynamics and synthesis of prostanoids by histotropic stages cultured in vitro.
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Female; Indomethacin; Larva; Male; Morphogenesis; Oesophagostomum; Prostaglandin D2; Prostaglandins; Swine; Thromboxane B2 | 1995 |
Effects of dietary fibre on dimethylhydrazine-induced changes in prostanoid concentrations in rat colonic mucosa.
Topics: 1,2-Dimethylhydrazine; 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Carcinogens; Chromatography, High Pressure Liquid; Colon; Colonic Neoplasms; Dietary Fiber; Dimethylhydrazines; Dinoprostone; Galactans; Injections, Subcutaneous; Intestinal Mucosa; Male; Mannans; Plant Gums; Prostaglandin D2; Prostaglandins; Rats; Rats, Sprague-Dawley; Thromboxane B2 | 1995 |
Aspirin-like molecules that covalently inactivate cyclooxygenase-2.
Topics: Acetylation; Acetylene; Alkynes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Cell Division; Cell Line; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Drug Design; Humans; Indomethacin; Isoenzymes; Macrophages; Membrane Proteins; Mutagenesis, Site-Directed; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Sulfides; Thromboxane B2; Tumor Cells, Cultured | 1998 |
Cyclo-oxygenase-2 mediates P2Y receptor-induced reactive astrogliosis.
Topics: Adenosine Triphosphate; Animals; Aspirin; Astrocytes; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gliosis; Isoenzymes; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Receptors, Purinergic P2; Sulfonamides; Time Factors | 1999 |
Differential metabolism of arachidonic acid in nasal polyp epithelial cells cultured from aspirin-sensitive and aspirin-tolerant patients.
Topics: Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Asthma; Cattle; Cells, Cultured; Dinoprostone; Drug Hypersensitivity; Female; Humans; Hydroxyeicosatetraenoic Acids; Male; Middle Aged; Nasal Polyps; Prostaglandin D2; Respiratory Mucosa | 2000 |
A comparative study of eicosanoid concentrations in sputum and urine in patients with aspirin-intolerant asthma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Drug Hypersensitivity; Eicosanoids; Eosinophil-Derived Neurotoxin; Eosinophils; Female; Humans; Leukocyte Count; Leukotriene E4; Male; Middle Aged; Prostaglandin D2; Rhinitis; Ribonucleases; Sinusitis; Sputum | 2002 |
A key role for old yellow enzyme in the metabolism of drugs by Trypanosoma cruzi.
Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Base Sequence; Catalysis; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; DNA, Protozoan; Gene Expression; Hydroxyprostaglandin Dehydrogenases; Indomethacin; Molecular Sequence Data; NADPH Dehydrogenase; Naphthoquinones; Oxidation-Reduction; Prostaglandin D2; Sequence Homology, Amino Acid; Trypanocidal Agents; Trypanosoma cruzi | 2002 |
A controlled study of 9alpha,11beta-PGF2 (a prostaglandin D2 metabolite) in plasma and urine of patients with bronchial asthma and healthy controls after aspirin challenge.
Topics: Adult; Aged; Aspirin; Asthma; Dinoprost; Female; Humans; Leukotriene E4; Male; Middle Aged; Prostaglandin D2; Serine Endopeptidases; Tryptases | 2003 |
Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma.
Topics: Adult; Aged; Aspirin; Asthma; Bronchi; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Female; Fibroblasts; Humans; Indomethacin; Isoenzymes; Male; Membrane Proteins; Middle Aged; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases | 2003 |
PPARgamma ligands attenuate mesangial contractile dysfunction in high glucose.
Topics: Actins; Angiotensin II; Animals; Aspirin; Cells, Cultured; Cyclooxygenase Inhibitors; DNA, Antisense; Enzyme Inhibitors; Flavonoids; Gene Expression; Glomerular Mesangium; Glucose; Hypoglycemic Agents; Indomethacin; Ligands; Pioglitazone; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thiazolidinediones; Transcription Factors; Vasoconstrictor Agents | 2004 |
Aspirin increases CD36, SR-BI, and ABCA1 expression in human THP-1 macrophages.
Topics: Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Blotting, Western; CD36 Antigens; Cell Line; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Flow Cytometry; Humans; Macrophages; PPAR alpha; PPAR gamma; PPAR-beta; Prostaglandin D2; Receptors, Immunologic; Receptors, Scavenger; Time Factors | 2005 |
2-(2-Br-phenyl)-8-methoxy-benzoxazinone (HPW-RX2), a direct thrombin inhibitor with a suppressive effect on thromboxane formation in platelets.
Topics: Adenosine Triphosphate; Arachidonic Acid; Aspirin; Benzoxazines; Blood Platelets; Calcium; Calcium Signaling; Collagen; Dose-Response Relationship, Drug; Humans; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin D2; Receptors, Thrombin; Thrombin; Thromboxane A2; Thromboxane B2 | 2005 |
Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans.
Topics: Adolescent; Adult; Animals; Aspirin; Female; Flushing; Humans; Hydantoins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Niacin; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Receptors, Immunologic; Receptors, Prostaglandin; Vasodilation | 2006 |
Role of COX-1 and COX-2 on skin PGs biosynthesis by mechanical scratching in mice.
Topics: Animals; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Epoprostenol; Mice; Prostaglandin D2; Prostaglandins; Pruritus; Skin; Up-Regulation | 2006 |
Nicotinic acid induces secretion of prostaglandin D2 in human macrophages: an in vitro model of the niacin flush.
Topics: Aspirin; Calcimycin; Calcium; Flushing; Humans; Macrophages; Models, Biological; Niacin; Nicotinic Acids; Prostaglandin D2; Tumor Cells, Cultured | 2007 |
PGE suppresses excessive anti-IgE induced cysteinyl leucotrienes production in mast cells of patients with aspirin exacerbated respiratory disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Anti-Idiotypic; Aspirin; Bronchial Spasm; Cells, Cultured; Cysteine; Dinoprostone; Female; Histamine; Humans; Immunoglobulin E; Leukotrienes; Male; Mast Cells; Prostaglandin D2 | 2007 |
Deficiency of cyclooxygenases transcripts in cultured primary bronchial epithelial cells of aspirin-sensitive asthmatics.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Asthma; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Drug Hypersensitivity; Female; Gene Expression Regulation, Enzymologic; Humans; Male; Middle Aged; Prostaglandin D2; RNA, Messenger | 2007 |
The flavonoid luteolin inhibits niacin-induced flush.
Topics: Animals; Aspirin; Body Temperature; Disease Models, Animal; Flushing; Hypolipidemic Agents; Luteolin; Male; Niacin; Prostaglandin D2; Quercetin; Random Allocation; Rats; Rats, Sprague-Dawley; Serotonin; Skin | 2008 |
Prevention of mast cell activation disorder-associated clinical sequelae of excessive prostaglandin D(2) production.
Topics: Adult; Anaphylaxis; Aspirin; Female; Histamine Release; Humans; Male; Mast Cells; Mastocytosis; Middle Aged; Prostaglandin D2; Tryptases | 2008 |
Correlation between the prostaglandin D(2)/E(2) ratio in nasal polyps and the recalcitrant pathophysiology of chronic rhinosinusitis associated with bronchial asthma.
Topics: Adult; Aged; Aspirin; Asthma; Cell Extracts; Chronic Disease; Dinoprostone; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Nasal Polyps; Paranasal Sinuses; Prostaglandin D2; Rhinitis; Sinusitis | 2008 |
Reduction of nuclear peroxisome proliferator-activated receptor gamma expression in methamphetamine-induced neurotoxicity and neuroprotective effects of ibuprofen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Temperature; Central Nervous System Stimulants; Corpus Striatum; Cyclooxygenase 1; Cyclooxygenase 2; Dopamine Plasma Membrane Transport Proteins; Fever; Ibuprofen; Immunohistochemistry; Male; Membrane Proteins; Methamphetamine; Mice; Mice, Inbred BALB C; Microglia; Neuroprotective Agents; PPAR gamma; Prostaglandin D2 | 2009 |
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Atherosclerosis; Benzofurans; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Down-Regulation; Endothelial Cells; Epoprostenol; Heme Oxygenase-1; Humans; Inflammation; Nitrobenzenes; Perfusion; Propionates; Prostaglandin D2; Receptors, Epoprostenol; Receptors, Prostaglandin; Stress, Mechanical; Sulfonamides; Tumor Necrosis Factor-alpha; Up-Regulation | 2009 |
Survey of aspirin administration in systemic mastocytosis.
Topics: Aspirin; Dinoprost; Drug Administration Schedule; Humans; Mastocytosis, Systemic; Platelet Aggregation Inhibitors; Prostaglandin D2 | 2009 |
Stable expression of lipocalin-type prostaglandin D synthase in cultured preadipocytes impairs adipogenesis program independently of endogenous prostanoids.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Aspirin; Cell Differentiation; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Drug Evaluation, Preclinical; Gene Expression Regulation, Enzymologic; Intramolecular Oxidoreductases; Lipocalins; Mice; Mice, Inbred BALB C; PPAR gamma; Prostaglandin D2; Prostaglandins; Stem Cells; Transfection | 2012 |
In vivo impact of prodrug isosorbide-5-nicotinate-2-aspirinate on lipids and prostaglandin D2: is this a new immediate-release therapeutic option for niacin?
Topics: Animals; Apolipoproteins B; Aspirin; Blood Glucose; Chemistry, Pharmaceutical; Cholesterol, LDL; Cyclooxygenase Inhibitors; Hyperglycemia; Hypolipidemic Agents; Isosorbide; Lipid Metabolism; Lipids; Macaca fascicularis; Models, Biological; Niacin; Postprandial Period; Prodrugs; Prostaglandin D2; Salicylates; Thromboxane B2; Triglycerides | 2012 |
Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.
Topics: Acetaminophen; Androgen Antagonists; Animals; Arachidonic Acid; Aspirin; Cryptorchidism; Endocrine Disruptors; Female; Indomethacin; Male; Pregnancy; Prostaglandin D2; Rats; Testis; Testosterone | 2012 |
Cardiac-generated prostanoids mediate cardiac myocyte apoptosis after myocardial ischaemia.
Topics: Animals; Animals, Newborn; Apoptosis; Aspirin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Disease Models, Animal; Fas Ligand Protein; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Myocardial Ischemia; Myocardium; Prostaglandin D2; Prostaglandins; Receptors, Immunologic; Receptors, Prostaglandin; RNA, Messenger; Time Factors; Up-Regulation; Ventricular Function, Left | 2012 |
Low-dose aspirin delays an inflammatory tumor progression in vivo in a transgenic mouse model of neuroblastoma.
Topics: Animals; Aspirin; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Dendritic Cells; Disease Models, Animal; Disease Progression; Homozygote; Immunity, Innate; Inflammation; Macrophages; Mice; Mice, Transgenic; Neuroblastoma; Prostaglandin D2; Th2 Cells; Thromboxane A2; Transforming Growth Factor beta | 2013 |
Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation.
Topics: Aspirin; Blood Platelets; Calcium; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Esterification; Feedback, Physiological; Humans; Intracellular Space; MAP Kinase Kinase 1; Phosphatidylethanolamines; Phospholipids; Platelet Activation; Prostaglandin D2; Prostaglandins; Protein Kinase C; Receptor, PAR-1; src-Family Kinases; Thrombin | 2013 |
Aspirin treatment improved mesenchymal stem cell immunomodulatory properties via the 15d-PGJ2/PPARγ/TGF-β1 pathway.
Topics: Animals; Apoptosis; Aspirin; Cell Proliferation; Cells, Cultured; Coculture Techniques; Colitis; Dinoprostone; Female; Immunomodulation; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Inbred C57BL; PPAR gamma; Prostaglandin D2; Signal Transduction; T-Lymphocytes, Regulatory; Th17 Cells; Transforming Growth Factor beta1 | 2014 |
Expression of DP2 (CRTh2), a prostaglandin D₂ receptor, in human mast cells.
Topics: Aspirin; Calcium; Cell Degranulation; Cell Line; Cytosol; Gene Expression; Humans; Ion Transport; K562 Cells; Leukocytes, Mononuclear; Mast Cells; Nasal Polyps; Pertussis Toxin; Primary Cell Culture; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; RNA, Messenger | 2014 |
Aspirin-Exacerbated Respiratory Disease--New Prime Suspects.
Topics: Aspirin; Asthma; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Homeostasis; Humans; Nasal Polyps; Prostaglandin D2; Sinusitis | 2016 |
Clinical benefits of aspirin desensitization in patients with nonsteroidal anti-inflammatory drug exacerbated respiratory disease are not related to urinary eicosanoid release and are accompanied with decreased urine creatinine.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Creatine; Desensitization, Immunologic; Drug Hypersensitivity; Eicosanoids; Humans; Leukotrienes; Prostaglandin D2; Respiratory Tract Diseases; Sinusitis | 2016 |
Eosinophil production of prostaglandin D
Topics: Aspirin; Asthma, Aspirin-Induced; Cells, Cultured; Cyclooxygenase Inhibitors; Eosinophils; Gene Expression Regulation; Humans; Paranasal Sinuses; Prostaglandin D2 | 2016 |
Association of interleukin-25 levels with development of aspirin induced respiratory diseases.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; Cytokines; Female; Forced Expiratory Volume; Humans; Immunity, Innate; Interleukin-17; Interleukin-33; Leukotriene C4; Male; Middle Aged; Prostaglandin D2; Thymic Stromal Lymphopoietin | 2017 |
Aspirin desensitization in aspirin-exacerbated respiratory disease: New insights into the molecular mechanisms.
Topics: Adult; Aged; Aspirin; Asthma, Aspirin-Induced; Cytokines; Desensitization, Immunologic; Disease Progression; Female; Humans; Male; Middle Aged; Prospective Studies; Prostaglandin D2; Thymic Stromal Lymphopoietin; Young Adult | 2018 |
Aspirin-exacerbated Respiratory Disease: A Syndrome of Mast Cell-mediated PgD2 Overproduction.
Topics: Aspirin; Biomarkers; Mast Cells; Prospective Studies; Prostaglandin D2 | 2019 |
A genetic variant near TSLP is associated with chronic rhinosinusitis with nasal polyps and aspirin-exacerbated respiratory disease in Japanese populations.
Topics: Aspirin; Cytokines; Humans; Japan; Nasal Polyps; Prostaglandin D2; Thymic Stromal Lymphopoietin | 2020 |