aspirin and prazosin

aspirin has been researched along with prazosin in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19904 (12.12)18.7374
1990's9 (27.27)18.2507
2000's12 (36.36)29.6817
2010's8 (24.24)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, KS; Ko, FN; Teng, CM; Wu, YC1
Chen, KS; Ko, FN; Teng, CM; Wu, TS; Wu, YC1
Chang, YL; Chen, IS; Chen, TL; Lin, WY; Teng, CM1
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Aranyi, Z; Ballagi-Pordány, G; Hadházy, P; Koltai, MZ; Pogátsa, G; Rösen, P1
Fujiwara, M; Kurahashi, K; Taniguchi, T; Tsukahara, T; Usui, H1
Godfraind, T; Schoeffter, P1
Conti, CR1
Fujiwara, M; Fukui, K; Kurahashi, K; Shirahase, H; Usui, H1
Gulati, A; Rebello, S1
Bilello, K; Cole, F; Jaffin, J; Malcolm, D; Powell, C; Schultz, S1
Gulati, A; Sharma, AC1
Bertolino, F; Fauré, P; John, GW; Valentin, JP; Vieu, S1
Dube, SN; Gupta, AK; Kaushik, MP; Kumar, D; Mazumder, PK1
Callingham, BA; Davidson, HJ; Hiley, CR; Ho, WS; Ritchie, AJ; Vuylsteke, A; White, R1
Anesini, C; Borda, E; Coussio, J; Ferraro, G; Turner, S1
Gokee, A; Rocchini, AP; Yang, JQ1
Ong, CT; Sung, SF; Tong, SH; Wu, CS1
Cheng, FY; Lü, HX; Zhang, ZH; Zhou, JP1

Reviews

2 review(s) available for aspirin and prazosin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Large vessel coronary vasospasm: diagnosis, natural history and treatment.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aspirin; Coronary Artery Bypass; Coronary Disease; Coronary Vasospasm; Diltiazem; Electrocardiography; Epoprostenol; Female; Fibrinolytic Agents; Humans; Isosorbide Dinitrate; Male; Nifedipine; Nitrates; Prazosin; Verapamil

1985

Other Studies

31 other study(ies) available for aspirin and prazosin

ArticleYear
Antiplatelet of vasorelaxing actions of some benzylisoquinoline and phenanthrene alkaloids.
    Journal of natural products, 1996, Volume: 59, Issue:5

    Topics: Alkaloids; Animals; Aorta, Thoracic; Female; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Platelet Aggregation Inhibitors; Rabbits; Rats; Vasodilator Agents

1996
Bioactive alkaloids from Illigera luzonensis.
    Journal of natural products, 1997, Volume: 60, Issue:6

    Topics: Alkaloids; Animals; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Plant Stems; Plants, Medicinal; Platelet Aggregation Inhibitors; Rabbits; Rats

1997
Chemical constituents and biological activities of the fruit of Zanthoxylum integrifoliolum.
    Journal of natural products, 1999, Volume: 62, Issue:6

    Topics: Animals; Aorta; Chromatography, Thin Layer; Furans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Muscle, Smooth, Vascular; Philippines; Plants, Medicinal; Platelet Aggregation Inhibitors; Rabbits; Rats; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Taiwan; Vasodilation

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Disturbed lipid metabolism in diabetic coronary vessels.
    Molecular and cellular biochemistry, 1992, Feb-12, Volume: 109, Issue:2

    Topics: Alloxan; Animals; Arachidonic Acids; Aspirin; Coronary Circulation; Coronary Vessels; Diabetes Mellitus, Experimental; Dogs; Epoprostenol; Female; Indomethacin; Male; Microcirculation; Myocardium; Norepinephrine; Phentolamine; Prazosin; Prostaglandin-Endoperoxide Synthases; Receptors, Adrenergic, alpha; Thromboxane A2; Vasoconstriction

1992
Differences in contractile responses to electrical stimulation and alpha-adrenergic binding sites in isolated cerebral arteries of humans, cows, dogs, and monkeys.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 3

    Topics: Animals; Aspirin; Cattle; Cerebral Arteries; Dogs; Electric Stimulation; Female; Humans; In Vitro Techniques; Macaca; Norepinephrine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Serotonin; Species Specificity; Vasoconstriction; Yohimbine

1985
Spontaneous rhythmic contractions of human saphenous veins isolated from old subjects are sensitive to cyclooxygenase inhibitors.
    Experientia, 1989, May-15, Volume: 45, Issue:5

    Topics: Adult; Aged; Aging; Aspirin; Coronary Artery Bypass; Cyclooxygenase Inhibitors; Female; Histamine; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle Development; Muscle, Smooth; Nifedipine; Norepinephrine; Phentolamine; Prazosin; Pyrilamine; Saphenous Vein

1989
Endothelium-dependent vasocontraction in response to noradrenaline in the canine cerebral artery.
    Japanese journal of pharmacology, 1987, Volume: 44, Issue:2

    Topics: Animals; Aspirin; Cerebral Arteries; Dogs; Endothelium; Female; In Vitro Techniques; Male; Methacrylates; Norepinephrine; Prazosin; Serotonin; Thromboxane A2; Thromboxane-A Synthase; Vasoconstriction; Yohimbine

1987
Diaspirin cross-linked hemoglobin (DCLHB): involvement of adrenergic mechanisms in the pressor effect.
    Artificial cells, blood substitutes, and immobilization biotechnology, 1994, Volume: 22, Issue:3

    Topics: Adrenal Medulla; Adrenalectomy; Animals; Aspirin; Blood Pressure; Blood Substitutes; Clonidine; Drug Interactions; Hemoglobins; Male; Phenylephrine; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Yohimbine

1994
Diaspirin crosslinked hemoglobin (DCLHb): control of pressor effect with anti-hypertensive agents.
    Artificial cells, blood substitutes, and immobilization biotechnology, 1994, Volume: 22, Issue:3

    Topics: Animals; Antihypertensive Agents; Aspirin; Blood Pressure; Blood Substitutes; Hemoglobins; Hypertension; Labetalol; Nicardipine; Nitroglycerin; Prazosin; Rats

1994
Prazosin blocks the pressor but not the regional circulatory effects of diaspirin crosslinked hemoglobin.
    Life sciences, 1994, Volume: 55, Issue:2

    Topics: Animals; Aspirin; Blood Pressure; Drug Interactions; Hemodynamics; Hemoglobins; Male; Prazosin; Rats; Rats, Sprague-Dawley; Regional Blood Flow

1994
Differential involvement of serotonin 2A/C and thromboxane A2/prostanoid receptors in high- vs. low-shear rate arterial thrombosis in rabbits.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: Animals; Arteriovenous Shunt, Surgical; Aspirin; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Carotid Arteries; Carotid Stenosis; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart Rate; Hemodynamics; Hydrazines; Jugular Veins; Ketanserin; Male; Oxadiazoles; Piperazines; Platelet Aggregation; Prazosin; Rabbits; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Prostaglandin; Receptors, Serotonin; Receptors, Thromboxane; Ritanserin; Serotonin Antagonists; Stress, Mechanical

1997
Cardiovascular effects of an organophosphate toxin isolated from Ptychodiscus brevis.
    Biomedical and environmental sciences : BES, 1997, Volume: 10, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Aspirin; Atropine; Cardiovascular System; Cholinesterase Inhibitors; Cimetidine; Dinoflagellida; Dose-Response Relationship, Drug; Drug Interactions; Ganglionic Blockers; Hexamethonium; Histamine H2 Antagonists; Humans; Male; Marine Toxins; Muscarinic Antagonists; Neostigmine; Organophosphorus Compounds; Platelet Aggregation Inhibitors; Potassium Channels; Prazosin; Rats; Rats, Wistar; Vasoconstriction

1997
Effect of the blood substitute diaspirin crosslinked hemoglobin in rat mesenteric and human radial collateral arteries.
    Journal of cardiovascular pharmacology, 2001, Volume: 37, Issue:4

    Topics: Animals; Antihypertensive Agents; Arteries; Aspirin; Blood Substitutes; Bucladesine; Carbachol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hemoglobins; Humans; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Middle Aged; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptides, Cyclic; Prazosin; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents

2001
Effect of Larrea divaricata Cav. extract and nordihydroguaiaretic acid upon peroxidase secretion in rat submandibulary glands.
    Pharmacological research, 2004, Volume: 49, Issue:5

    Topics: 3,3'-Diaminobenzidine; Animals; Argentina; Aspirin; Atenolol; Butoxamine; Dinoprostone; Dobutamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Forecasting; Larrea; Masoprocol; Peroxidase; Plant Extracts; Plant Leaves; Prazosin; Propranolol; Rats; Rats, Wistar; Submandibular Gland; Water

2004
Hypertension and insulin resistance are not directly related in obese dogs.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Aspirin; Atenolol; Blood Glucose; Clonidine; Diet, Sodium-Restricted; Dietary Fats; Dogs; Female; Furosemide; Hemodynamics; Hypertension; I-kappa B Kinase; Insulin; Insulin Resistance; Male; Models, Animal; Models, Biological; Obesity; Prazosin; Protein Serine-Threonine Kinases; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sympathetic Nervous System

2004
Multiple cerebral infarctions related to famotidine-induced eosinophilia.
    Journal of neurology, 2012, Volume: 259, Issue:10

    Topics: Acarbose; Adrenergic alpha-1 Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antihypertensive Agents; Aspirin; Calcium Channel Blockers; Cerebral Infarction; Diabetes Mellitus, Type 2; Diffusion Magnetic Resonance Imaging; Drug-Related Side Effects and Adverse Reactions; Eosinophilia; Famotidine; Humans; Hypertension; Hypoglycemic Agents; Labetalol; Male; Metformin; Middle Aged; Nifedipine; Peptic Ulcer; Prazosin; Sulfonylurea Compounds

2012
[The effects and its mechanism of N-arginine chitosan as transdermal enhancer].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:8

    Topics: Administration, Cutaneous; Animals; Arginine; Aspirin; Cell Line; Cell Survival; Cell-Penetrating Peptides; Chitosan; Drug Carriers; Humans; Isosorbide Dinitrate; Keratinocytes; Male; Mice; Prazosin; Skin Absorption

2013