aspirin and piperidines

aspirin has been researched along with piperidines in 89 studies

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-199026 (29.21)18.7374
1990's18 (20.22)18.2507
2000's30 (33.71)29.6817
2010's13 (14.61)24.3611
2020's2 (2.25)2.80

Authors

AuthorsStudies
Debelic, M; Radielovic, P; Wuethrich, B1
Wüthrich, B1
Igarashi, T; Morishima, Y; Shibano, T; Tanaka, T; Watanabe, K; Yasuoka, M1
Bezek, S; Durisová, M; Kállay, Z; Kukan, M; Laginová, V; Scasnár, V; Svoboda, V; Trnovec, T1
Kienast, J; Verstraete, M1
Chap, H; Douste-Blazy, L; Hullin, F; Pascal, M; Ragab-Thomas, JM; Sepulchre, C1
Buyniski, JP; Cavanagh, RL1
Borella, L; Failli, A; Grimes, D; Mir, GN; Rimele, TJ; Russell, J1
Hladovec, J2
Kimura, Y; Nakase, H; Watanabe, K1
Hamada, K; Okada, Y; Sekiguchi, H; Taga, F1
Dodge, JA; Hamdi, I1
Burton, JA; Ferguson, D; Lindsay, RM; McNicol, GP; Prentice, CR1
Towne, JC; Williams, CS; Williams, MW; Williford, EA1
Bennert, C; Berger, E; Jäger, W; Kauschmann, R; Kutschera, J; Pietsch, U; Riese, W; Wendeberg, H1
Riethe, P; Wilske, E1
Doenicke, A; Konrad, T; Kugler, J; Laub, M; Wittmann, R1
Emele, JF; Shanaman, JE1
Czerniawska-Mysik, G; Kuklinski, P; Serwonska, M; Szczeklik, A2
Dugdale, M; Johnson, RW; Lasslo, A; Naylor, JL; Quintana, RP1
Caro-Paton Gómez, A; Casas Carnicero, J; Dueñas Laita, A; Fernández de la Gandara, F1
Blackett, A; Brion, N; Turner, P1
Johnson, N; Leeling, J; Muni, I1
Montero, MJ; Palacios, B; Román, LS; Sevilla, MA1
Hamada, K; Nishino, K; Sekiguchi, H; Taga, F1
Morishima, Y; Shibano, T; Shibutani, T; Tanaka, T; Watanabe, K; Yasuoka, M1
Aronowski, J; Grotta, JC; Strong, R1
Grip, L; Mattsson, C; Rydén, L; Sjöquist, PO; Uriuda, Y; Wang, QD1
Börjesson, I; Elg, M; Gustafsson, D; Lenfors, S; Teger-Nilsson, AC1
Bernat, A; Herbert, JM; Hoffmann, P; Savi, P2
Bernat, A; Herault, JP; Herbert, JM; Peyrou, V; Savi, P1
Hatori, N; Mattsson, C; Nordlander, R; Rydén, L; Sjöquist, PO; Uriuda, Y; Wang, QD1
Christian, BJ; Lin, YS; Modi, NB; Reynolds, T; Shaheen, A1
Hotta, K; Ichikawa, T; Ishihara, K; Ivanov, C; Klouchek, E; Krushkov, I; Marazova, K; Popov, A1
Bina, S; Hart, J; Jing, M; Ledvina, MA; Muldoon, S1
Newby, LK1
Kanamaru, M; Kozawa, O; Matsuno, H; Nagashima, S; Uematsu, T1
Ayukawa, O; Kariyazono, H; Moriyama, Y; Nakamura, K; Shinkawa, T; Taira, A; Toyohira, H; Yamada, K; Yamaguchi, T; Yamashita, T; Yotsumoto, G1
Hamm, CW; Heeschen, C1
Birnböck, H; Chung, J; Ensor, H; Ertel, SI; Lausecker, B; Machin, SJ; MacKie, IJ; Wittke, B1
Breddin, HK; Graff, J; Harder, S; Kirchmaier, CM; Klinkhardt, U; Mahnel, R; Westrup, D1
Modi, NB; Novotny, W; Reimann, JD1
Bernat, A; Herbert, JM; Lalé, A; Roque, C; Savi, P; Zamboni, G1
McGuire, DK; Newby, LK2
Altman, DG1
Verheugt, FW1
Bari, M; Del Principe, D; Finazzi-Agrò, A; Giuliani, E; MacCarrone, M; Menichelli, A1
Bhatt, DL; Chew, DP; Sapp, S; Topol, EJ1
Davis, CJ; Lowry, DR; McKenzie, ME; Nair, GV; Serebruany, VL1
Armstrong, PW; Califf, RM; Cantor, WJ; Christenson, RH; Hasselblad, V; Moliterno, DJ; Newby, LK; Ohman, EM; Topol, EJ; Tuttle, RH1
Aylward, PE; Bhapkar, MV; Califf, RM; Dimas, AP; Klein, WW; Kristinsson, A; McGuire, DK; Moliterno, DJ; Newby, LK; Verheugt, FW; Weaver, WD1
McRae, T; Orazem, J; Reichman, WE; Relkin, NR1
Amarenco, P; Califf, RM; Davis, S; Diener, HC; Easton, D; Ferguson, J; Fitzgerald, D; Graffagnino, C; Granett, J; Harrington, RA; Koudstaal, PJ; Pieper, K; Shuaib, A; Sigmon, K; Theroux, P; Topol, EJ; Vallee, M; Van de Werf, F; Willerson, JT1
Berger, PB; Bhapkar, MV; Califf, RM; Harrington, RA; Moliterno, DJ; Newby, LK; Ohman, EM; Tolleson, TR; Topol, EJ; Van de Werf, F; Verheugt, FW; White, HD1
LASAGNA, L; PEARSON, JW1
Tendera, M; Wojakowski, W1
Bhapkar, MV; Califf, RM; Graffagnino, C; Kassem-Moussa, H; Mahaffey, KW; Newby, LK; Sila, CA; Simes, RJ; Tasissa, G; White, HD1
Armstrong, PW; Califf, RM; Granger, CB; Lee, KL; Newby, LK; Simes, RJ; Van de Werf, F; White, HD1
Alexander, KP; Bhapkar, MV; Bushnell, CD; Califf, RM; Newby, LK; Parsons, E; Shah, SH; White, HD1
Badenhorst, HE; Daya, S; Maharaj, DS; Malan, SF; van Dyk, S1
Schaerlig, E1
Aoki, T; Furuichi, Y; Maeda, M; Matsuoka, N; Mihara, K; Moriguchi, A; Mutoh, S1
Aboul-Enein, HY; Nakashima, K; Nishiwaki, J; Ohwaki, Y; Wada, M; Yamane, T1
Matsuda, H; Nagatomo, A; Ochi, M; Yoshikawa, M1
Alexander, KP; Armstrong, PW; Aylward, PE; Bhapker, MV; Califf, RM; Hochman, JS; Newby, LK; Pfisterer, M; Van de Werf, F; White, HD; Wong, CK1
WINDER, CV1
Menezes-de-Lima, O; Pamplona, FA; Takahashi, RN1
Abdellatif, KR; Chowdhury, MA; Das, D; Dong, Y; Huang, Z; Knaus, EE; Rahman, M; Suresh, MR; Velázquez, CA; Yu, G1
Filaferro, M; Frigeri, C; Pini, LA; Ruggieri, V; Sandrini, M; Vitale, G1
Barrett, F; Keown, OP; Leslie, SJ; Macrury, SM; Megson, IL; Neilson, I; Wainwright, CL; Winterburn, TJ1
Asaka, M; Imai, A; Kamada, G; Kato, M; Nakagawa, M; Nakagawa, S; Nishida, U; Ono, S; Shimizu, Y; Yamamoto, K; Yoshida, T1
Asano, N; Furuya, A; Ikemoto, K; Makino, K; Nonaka, A; Suzuki, S; Tamaki, F1
Azhar, KF; Haider, S; Miana, GA; Mushtaq, N; Naz, A; Nisa, M; Rasheed, H; Saify, ZS1
Ruella, M; Soubeyran, P1
Aggarwal, H; Barthwal, MK; Bihan, D; Dhankani, P; Dikshit, DK; Dikshit, M; Farndale, RW; Kumar, S; Misra, A; Pandey, CP; Prakash, P; Pugh, N1
Allahtavakoli, M; Kaeidi, A; Moghadam-Ahmadi, A; Rahmani, MR; Shamsizadeh, A1
Armanious, M; Chavez, JC; Emole, J; Fradley, MG; Gliksman, M; Lee, DH; McLeod, H; Pinilla-Ibarz, J; Rhea, I; Schabath, MB; Shah, B; Viganego, F; Walko, C; Welter-Frost, A1
Lin, FJ; Lin, SY; Wang, CC; Wei, Y1
Bako, HY; Ibrahim, MA; Ibrahim, S; Isah, MS1
Gao, B; Gao, W; Ji, Q; Wan, H; Xu, F; Zhang, X; Zhou, R1

Reviews

8 review(s) available for aspirin and piperidines

ArticleYear
Pharmacology of the interaction between platelets and vessel wall.
    Clinics in haematology, 1986, Volume: 15, Issue:2

    Topics: Animals; Aspirin; Blood Platelets; Blood Vessels; Dextrans; Diltiazem; Dipyridamole; Epoprostenol; Humans; Imidazoles; Ketanserin; Piperidines; Pyrazoles; Pyrazolones; Sulfinpyrazone; Sulfonamides; Thiophenes; Ticlopidine

1986
Oral platelet glycoprotein IIb/IIIa inhibition.
    Current cardiology reports, 2000, Volume: 2, Issue:5

    Topics: Alanine; Angina, Unstable; Aspirin; Benzamidines; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Syndrome; Treatment Outcome

2000
Oral glycoprotein IIb/IIIa antagonists: new insights from the SYMPHONY trial.
    Journal of thrombosis and thrombolysis, 2000, Volume: 10, Issue:2

    Topics: Administration, Oral; Aspirin; Clinical Trials, Phase III as Topic; Coronary Disease; Humans; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic

2000
Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists: a meta-analysis of phase III multicenter randomized trials.
    Circulation, 2001, Jan-16, Volume: 103, Issue:2

    Topics: Administration, Oral; Alanine; Aspirin; Benzamidines; Clinical Trials, Phase III as Topic; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hemorrhage; Humans; Incidence; Multicenter Studies as Topic; Myocardial Infarction; Oximes; Piperidines; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Randomized Controlled Trials as Topic

2001
Aspirin in patients with coronary artery disease: is it simply irresistible?
    Journal of thrombosis and thrombolysis, 2001, Volume: 11, Issue:2

    Topics: Abciximab; Antibodies, Monoclonal; Aspirin; Benzamidines; Clinical Trials as Topic; Clopidogrel; Coronary Disease; Cyclooxygenase Inhibitors; Diabetes Complications; Dipyridamole; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Endothelium, Vascular; Fibrinolytic Agents; Humans; Immunoglobulin Fab Fragments; Oximes; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Randomized Controlled Trials as Topic; Stroke; Thrombosis; Thromboxane-A Synthase; Ticlopidine; Vasodilator Agents

2001
Role of antiplatelet drugs in the prevention of cardiovascular events.
    Thrombosis research, 2003, Jun-15, Volume: 110, Issue:5-6

    Topics: Aspirin; Benzamidines; Clopidogrel; Coronary Artery Disease; Humans; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Stroke; Ticlopidine; Treatment Outcome

2003
Lessons learned from a clinical trial.
    Circulation, 2004, Dec-07, Volume: 110, Issue:23

    Topics: Aspirin; Biomedical Research; Coronary Disease; Drug Therapy, Combination; Drugs, Investigational; Human Experimentation; Humans; Interdisciplinary Communication; Multicenter Studies as Topic; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Professional Staff Committees; Quality of Health Care; Randomized Controlled Trials as Topic; Secondary Prevention

2004
Walking a tightrope: clinical use of ibrutinib in mantle cell lymphoma in the elderly.
    Hematology. American Society of Hematology. Education Program, 2016, Dec-02, Volume: 2016, Issue:1

    Topics: Adenine; Aged; Aspirin; Diarrhea; Hemorrhage; Humans; Lymphoma, Mantle-Cell; Male; Neoplasm Staging; Piperidines; Pyrazoles; Pyrimidines

2016

Trials

17 trial(s) available for aspirin and piperidines

ArticleYear
Protective effect of ketotifen and disodium cromoglycate against bronchoconstriction induced by aspirin, benzoic acid or tartrazine in intolerant asthmatics.
    Respiration; international review of thoracic diseases, 1979, Volume: 37, Issue:4

    Topics: Adult; Aged; alpha 1-Antitrypsin; Aspirin; Asthma; Benzoates; Bronchial Spasm; Complement C1 Inactivator Proteins; Cromolyn Sodium; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Piperidines; Tartrazine; Thiophenes

1979
Reduction of thrombus formation on dialyser membranes by aspirin and RA 233.
    Lancet (London, England), 1972, Dec-16, Volume: 2, Issue:7790

    Topics: Aspirin; Blood Cell Count; Blood Coagulation; Blood Platelets; Clinical Trials as Topic; Drug Synergism; Ethanolamines; Factor V; Female; Heparin; Humans; Kidneys, Artificial; Male; Piperidines; Placebos; Plasminogen; Platelet Adhesiveness; Pyrimidines; Renal Dialysis; Thrombosis

1972
[Analgetic effects on the stimulus threshold of the human tooth].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:4

    Topics: Administration, Oral; Amides; Analgesics; Analysis of Variance; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Differential Threshold; Drug Evaluation; Electric Stimulation; Fumarates; Humans; Pain; Phenacetin; Phenobarbital; Piperidines; Placebos; Propionates; Pyridines; Toothache

1974
[Electroencephalographic determination of vigilance following DL-propiramfumarate].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:4

    Topics: Amides; Analgesics; Aspirin; Attention; Caffeine; Clinical Trials as Topic; Codeine; Drug Synergism; Electroencephalography; Electrooculography; Ethanol; Eye Movements; Female; Fumarates; Humans; Male; Phenacetin; Phenobarbital; Piperidines; Placebos; Promethazine; Propionates; Pyridines

1974
Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: a randomised trial. The SYMPHONY Investigators. Sibrafiban versus Aspirin to Yield Maximum Protection from Ischemic Heart Events Post-acute Coron
    Lancet (London, England), 2000, Jan-29, Volume: 355, Issue:9201

    Topics: Administration, Oral; Aged; Angina, Unstable; Aspirin; Double-Blind Method; Female; Humans; Male; Middle Aged; Odds Ratio; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recurrence

2000
Pharmacokinetics and pharmacodynamics of sibrafiban alone or in combination with ticlopidine and aspirin.
    British journal of clinical pharmacology, 2000, Volume: 49, Issue:3

    Topics: Adult; Aspirin; Drug Interactions; Humans; Male; Oximes; Piperidines; Platelet Aggregation Inhibitors; Prodrugs; Ticlopidine

2000
Pharmacokinetics and pharmacodynamics of sibrafiban, an orally administered GP IIb/IIIa antagonist, following coadministration of aspirin and heparin.
    Journal of clinical pharmacology, 2000, Volume: 40, Issue:5

    Topics: Adenosine Diphosphate; Administration, Oral; Adult; Anticoagulants; Area Under Curve; Aspirin; Bleeding Time; Cross-Over Studies; Drug Interactions; Female; Heparin; Humans; Male; Middle Aged; Oximes; Partial Thromboplastin Time; Peptide Fragments; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs; Prothrombin Time; Receptors, Thrombin

2000
Randomized trial of aspirin, sibrafiban, or both for secondary prevention after acute coronary syndromes.
    Circulation, 2001, Apr-03, Volume: 103, Issue:13

    Topics: Aged; Aspirin; Cause of Death; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Hemorrhage; Hospitalization; Humans; Male; Middle Aged; Myocardial Ischemia; Neovascularization, Physiologic; Oximes; Piperidines; Treatment Failure

2001
Prognostic significance of elevated troponin I after percutaneous coronary intervention.
    Journal of the American College of Cardiology, 2002, Jun-05, Volume: 39, Issue:11

    Topics: Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Biomarkers; Creatine Kinase; Creatine Kinase, MB Form; Disease-Free Survival; Female; Heart Diseases; Humans; Isoenzymes; Male; Middle Aged; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors; Prognosis; Prospective Studies; Sensitivity and Specificity; Stents; Troponin I

2002
A large, community-based, open-label trial of donepezil in the treatment of Alzheimer's disease.
    Dementia and geriatric cognitive disorders, 2003, Volume: 16, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Aspirin; Cholinesterase Inhibitors; Comorbidity; Donepezil; Female; Gastrointestinal Diseases; Humans; Indans; Male; Middle Aged; Piperidines; Risk Assessment; Vitamins

2003
Randomized, double-blind, placebo-controlled, international trial of the oral IIb/IIIa antagonist lotrafiban in coronary and cerebrovascular disease.
    Circulation, 2003, Jul-29, Volume: 108, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aspirin; Benzodiazepines; Cerebrovascular Disorders; Coronary Disease; Creatinine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Hemorrhage; Humans; Male; Middle Aged; Multivariate Analysis; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Proportional Hazards Models; Risk Assessment; Treatment Outcome

2003
Frequency of stent thrombosis after acute coronary syndromes (from the SYMPHONY and 2nd SYMPHONY trials).
    The American journal of cardiology, 2003, Aug-01, Volume: 92, Issue:3

    Topics: Acute Disease; Aspirin; Causality; Coronary Disease; Coronary Thrombosis; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardial Ischemia; Oximes; Piperidines; Platelet Aggregation Inhibitors; Postoperative Complications; Stents; Syndrome

2003
Incidence and characteristics of stroke during 90-day follow-up in patients stabilized after an acute coronary syndrome.
    American heart journal, 2004, Volume: 148, Issue:3

    Topics: Acute Disease; Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Aspirin; Coronary Artery Bypass; Female; Follow-Up Studies; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors; Proportional Hazards Models; Recurrence; Risk Factors; Stroke

2004
Use of evidence-based medicine for acute coronary syndromes in the elderly and very elderly: insights from the Sibrafiban vs aspirin to Yield Maximum Protection from ischemic Heart events postacute cOroNary sYndromes trials.
    American heart journal, 2007, Volume: 154, Issue:2

    Topics: Aged; Aged, 80 and over; Angina, Unstable; Aspirin; Cardiovascular Agents; Evidence-Based Medicine; Female; Humans; Male; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors

2007
Lafutidine prevents low-dose aspirin and loxoprofen induced gastric injury: a randomized, double-blinded, placebo controlled study.
    Journal of gastroenterology and hepatology, 2010, Volume: 25, Issue:10

    Topics: Acetamides; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Histamine H2 Antagonists; Humans; Male; Phenylpropionates; Piperidines; Pyridines; Stomach Diseases; Treatment Outcome; Young Adult

2010
Literature Commentary.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2021, 12-01, Volume: 41, Issue:4

    Topics: Aged; Aspirin; Humans; Ophthalmology; Piperidines; Pyridines; Pyrroles; Retrospective Studies; Spiro Compounds; Stroke

2021
Efficacy and safety of alogliptin versus acarbose in Chinese type 2 diabetes patients with high cardiovascular risk or coronary heart disease treated with aspirin and inadequately controlled with metformin monotherapy or drug-naive: A multicentre, randomi
    Diabetes, obesity & metabolism, 2022, Volume: 24, Issue:6

    Topics: Acarbose; Adult; Aspirin; Coronary Disease; Diabetes Mellitus, Type 2; Double-Blind Method; Glycated Hemoglobin; Heart Disease Risk Factors; Humans; Hypoglycemic Agents; Metformin; Piperidines; Prospective Studies; Treatment Outcome; Uracil

2022

Other Studies

64 other study(ies) available for aspirin and piperidines

ArticleYear
The protective effect of a new oral anti-asthma agent (ketotifen, HC 20--511) against experimentally induced bronchospasm (5 different models).
    International journal of clinical pharmacology and biopharmacy, 1978, Volume: 16, Issue:9

    Topics: Acetylcholine; Aerosols; Antigens; Aspirin; Benzoates; Bronchial Spasm; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Physical Exertion; Piperidines; Placebos; Tartrazine; Thiophenes

1978
Prevention by DV-7028, a selective 5-HT2 receptor antagonist, of the formation of coronary thrombi in dogs.
    Cardiovascular research, 1991, Volume: 25, Issue:9

    Topics: Animals; Aspirin; Coronary Thrombosis; Disease Models, Animal; Dogs; Drug Administration Schedule; Piperidines; Serotonin Antagonists; Triazines

1991
Irradiation of the head by 60Co opens the blood-brain barrier for drugs in rats.
    Experientia, 1990, Oct-15, Volume: 46, Issue:10

    Topics: Animals; Aspirin; Blood-Brain Barrier; Brain; Carbamates; Chloramphenicol; Cobalt Radioisotopes; Cranial Irradiation; Diazepam; Etimizol; Male; Piperidines; Rats; Rats, Inbred Strains; Regression Analysis

1990
Stimulation of 12-HETE production in human platelets by an immunomodulator, LF 1695. Evidence for activation of arachidonate liberation coupled to cyclo-oxygenase inhibition.
    Biochemical pharmacology, 1989, Sep-01, Volume: 38, Issue:17

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Adjuvants, Immunologic; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Calcimycin; Cyclooxygenase Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin

1989
Effect of BMY-25368, a potent and long-acting histamine H2-receptor antagonist, on gastric secretion and aspirin-induced gastric lesions in the dog.
    Alimentary pharmacology & therapeutics, 1989, Volume: 3, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Bethanechol Compounds; Dogs; Dose-Response Relationship, Drug; Female; Food; Gastric Acid; Histamine H2 Antagonists; Pentagastrin; Piperidines; Ranitidine; Stomach Ulcer

1989
Antisecretory and antiulcer activities of a potent new histamine H2-receptor antagonist with an intermediate duration of action.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:3

    Topics: Anesthesia; Animals; Anti-Ulcer Agents; Aspirin; Dimaprit; Dogs; Gastric Acid; Gastric Mucosa; Guinea Pigs; Heart Rate; Histamine H2 Antagonists; In Vitro Techniques; Macaca mulatta; Male; Muscle Contraction; Muscle, Smooth; Phenoxypropanolamines; Piperidines; Rats; Rats, Inbred Strains; Species Specificity; Thiadiazoles; Thiourea

1988
A sensitive model of venous thrombosis in rats.
    Thrombosis research, 1986, Sep-01, Volume: 43, Issue:5

    Topics: Animals; Anticoagulants; Aspirin; Dipyridamole; Disease Models, Animal; Female; Heparin; Ketanserin; Piperidines; Rats; Rats, Inbred Strains; Sulfinpyrazone; Thrombophlebitis; Time Factors

1986
Antithrombotics in view of thrombosis models.
    Thrombosis research, 1986, Sep-01, Volume: 43, Issue:5

    Topics: Animals; Anticoagulants; Arteries; Aspirin; Dipyridamole; Female; Hydroxyethylrutoside; Ketanserin; Piperidines; Pizotyline; Prenylamine; Rats; Rats, Inbred Strains; Sulfinpyrazone; Thrombophlebitis; Thrombosis

1986
Effect of cilostazol on experimental cerebral infarction in rabbits.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:7

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Azoles; Brain; Cerebral Infarction; Cilostazol; Injections, Intravenous; Piperidines; Rabbits; Tetrazoles; Vasodilator Agents

1986
[Effects of troxipide on acute gastric lesions in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1987, Volume: 89, Issue:3

    Topics: Acute Disease; Animals; Anti-Ulcer Agents; Aspirin; Ethanol; Gastric Mucosa; Hydrochloric Acid; Immersion; Male; Piperidines; Rats; Stomach Diseases; Stress, Physiological; Tranexamic Acid

1987
Toddler diarrhoea: observations on the effects of aspirin and loperamide.
    Journal of pediatric gastroenterology and nutrition, 1985, Volume: 4, Issue:3

    Topics: Antidiarrheals; Aspirin; Child, Preschool; Cyclooxygenase Inhibitors; Diarrhea; Diarrhea, Infantile; Humans; Infant; Loperamide; Piperidines; Prostaglandins F

1985
Clinical analgesic activity of dexoxadrol.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 178, Issue:1

    Topics: Analgesics; Arthritis; Aspirin; Codeine; Dioxoles; Drug Synergism; Humans; Neoplasms; Pain; Palliative Care; Piperidines

1969
[The continuous measurement of platelet aggregation without the addition of aggregation inducers. II. Experimental results and testing of aggregation inducers].
    Blut, 1974, Volume: 29, Issue:4

    Topics: Aspirin; Benzyl Compounds; Cycloheptanes; Dimethylamines; Ethanolamines; Fibrinogen; Humans; In Vitro Techniques; Morpholines; Photometry; Piperazines; Piperidines; Platelet Adhesiveness; Platelet Aggregation; Polysaccharides; Pyrimidines; Sulfuric Acids; Thiophenes

1974
Analgesic acitivity of namoxyrate (2-[4-biphenylyl] butyric acid 2-dimethylaminoethanol salt).
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 170, Issue:1

    Topics: Amino Alcohols; Analgesics; Animals; Aspirin; Biphenyl Compounds; Bradykinin; Butyrates; Codeine; Dextropropoxyphene; Female; Meperidine; Mice; Morphine; Phenols; Phenylbutazone; Piperidines; Quinones; Rats; Seizures

1967
Inhibition by ketotifen of idiosyncratic reactions to aspirin.
    Allergy, 1980, Volume: 35, Issue:5

    Topics: Adult; Aspirin; Asthma; Bronchi; Bronchial Spasm; Drug Hypersensitivity; Female; Histamine H1 Antagonists; Humans; Ketotifen; Male; Middle Aged; Piperidines; Placebos; Thiophenes

1980
Relationships between the chemical constitution of aggregation inhibitors and human blood platelet response profile.
    Biochimica et biophysica acta, 1984, Apr-25, Volume: 772, Issue:1

    Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Calcimycin; Calcium; Calcium Channel Blockers; Carbamates; Chlorpromazine; Gallic Acid; Humans; In Vitro Techniques; Piperidines; Platelet Aggregation; Propranolol; Thrombin

1984
[Changes in water, glucose, and electrolyte transport in the rat intestine "in vivo" after intraluminal injection of loperamide and aspirin].
    Revista espanola de las enfermedades del aparato digestivo, 1983, Volume: 64, Issue:3

    Topics: Animals; Aspirin; Biological Transport; Electrolytes; Glucose; Intestine, Small; Loperamide; Male; Piperidines; Rats; Rats, Inbred Strains; Water

1983
Recovery of acetylsalicylic acid and indalpine (LM 5008) after buccal partitioning.
    International journal of clinical pharmacology research, 1983, Volume: 3, Issue:1

    Topics: Absorption; Aspirin; Cheek; Chemistry, Pharmaceutical; Humans; Hydrogen-Ion Concentration; Kinetics; Mouth Mucosa; Piperidines

1983
Influence of broperamole, a new antiinflammatory agent, on gastrointestinal microbleeding in the dog.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dogs; Feces; Gastrointestinal Hemorrhage; Iron Radioisotopes; Male; Phenylbutazone; Piperidines; Time Factors

1980
Inhibition of idiosyncratic reactions to aspirin by ketotifen.
    Respiration; international review of thoracic diseases, 1980, Volume: 39 Suppl 1

    Topics: Adult; Aspirin; Asthma; Bronchial Spasm; Drug Hypersensitivity; Humans; Ketotifen; Piperidines; Thiophenes

1980
Aspirin or loperamide for childhood gastroenteritis.
    The Medical journal of Australia, 1980, Nov-29, Volume: 2, Issue:11

    Topics: Aspirin; Child; Gastroenteritis; Humans; Loperamide; Piperidines

1980
JB-9322, a new selective histamine H2-receptor antagonist with potent gastric mucosal protective properties.
    British journal of pharmacology, 1995, Volume: 115, Issue:1

    Topics: Animals; Aspirin; Ethanol; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Male; Muscarinic Antagonists; Piperidines; Ranitidine; Rats; Rats, Wistar; Stomach Diseases

1995
Effects of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl] urea with potent gastric mucosal protective activity on acute gastric lesions and duodenal ulcers in rats.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Cyanides; Duodenal Ulcer; Epirizole; Ethanol; Gastric Mucosa; Histamine H2 Antagonists; Hydrochloric Acid; Immersion; Intestinal Mucosa; Male; Phenylurea Compounds; Piperidines; Rats; Rats, Wistar; Stomach Ulcer; Stress, Psychological

1993
Combined effect of the 5-HT2 receptor antagonist DV-7028 and aspirin or heparin on coronary cyclic flow reductions in dogs.
    Cardiovascular research, 1993, Volume: 27, Issue:7

    Topics: Animals; Aspirin; Blood Pressure; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Drug Synergism; Heart Rate; Heparin; Piperidines; Serotonin Antagonists; Triazines; Ventricular Function, Left

1993
Combined neuroprotection and reperfusion therapy for stroke. Effect of lubeluzole and diaspirin cross-linked hemoglobin in experimental focal ischemia.
    Stroke, 1996, Volume: 27, Issue:9

    Topics: Animals; Aspirin; Cardiovascular Agents; Cerebral Infarction; Cerebrovascular Disorders; Drug Therapy, Combination; Hemodilution; Hemoglobins; Male; Neuroprotective Agents; Piperidines; Rats; Rats, Inbred Strains; Reperfusion; Thiazoles

1996
Antithrombotic activity of inogatran, a new low-molecular-weight inhibitor of thrombin, in a closed-chest porcine model of coronary artery thrombosis.
    Cardiovascular research, 1996, Volume: 32, Issue:2

    Topics: Animals; Aspirin; Coronary Thrombosis; Disease Models, Animal; Female; Glycine; Heparin; Male; Piperidines; Swine; Thrombin

1996
Effects of inogatran, a new low-molecular-weight thrombin inhibitor, in rat models of venous and arterial thrombosis, thrombolysis and bleeding time.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1996, Volume: 7, Issue:1

    Topics: Animals; Antithrombins; Arginine; Aspirin; Bleeding Time; Disease Models, Animal; Fibrinolytic Agents; Glycine; Heparin; Male; Molecular Weight; Pipecolic Acids; Piperidines; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Sulfonamides; Thrombolytic Therapy; Thrombophlebitis; Thrombosis

1996
Antiplatelet and antithrombotic efficacy of SR 121787, a nonpeptide orally active GP IIb/IIIa antagonist, in rabbits: comparison with clopidogrel and aspirin.
    Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:3

    Topics: Animals; Aspirin; Benzylamines; Clopidogrel; Hemodynamics; Hemostasis; Male; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rabbits; Thiazoles; Thrombosis; Ticlopidine

1997
Effect of SR121566A, a potent GP IIb-IIIa antagonist on platelet-mediated thrombin generation in vitro and in vivo.
    Thrombosis and haemostasis, 1998, Volume: 79, Issue:2

    Topics: Animals; Aspirin; Benzylamines; Blood Platelets; Cells, Cultured; Humans; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rabbits; Thiazoles; Thrombin

1998
Coronary thrombosis/thrombolysis in pigs: effects of heparin, ASA, and the thrombin inhibitor inogatran.
    Journal of pharmacological and toxicological methods, 1998, Volume: 39, Issue:2

    Topics: Animals; Antithrombins; Aspirin; Blood Flow Velocity; Coronary Thrombosis; Glycine; Hemodynamics; Heparin; Myocardial Ischemia; Piperidines; Reperfusion Injury; Swine; Thrombolytic Therapy

1998
Prevention of thrombosis and enhancement of thrombolysis in rabbits by SR 121787, a glycoprotein II/III antagonist.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:2

    Topics: Animals; Aspirin; Benzylamines; Bleeding Time; Carotid Artery Injuries; Collagen; Fibrinolytic Agents; Hemostasis; In Vitro Techniques; Jugular Veins; Male; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rabbits; Thiazoles; Thrombocytopenia; Thrombosis

1998
Pharmacokinetics and pharmacodynamics of sibrafiban (Ro 48-3657), an orally active IIb/IIIa antagonist, administered alone or in combination with heparin, aspirin, and recombinant tissue-type plasminogen activator in beagles.
    Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:3

    Topics: Administration, Oral; Amidines; Animals; Aspirin; Bleeding Time; Dogs; Heparin; Heterocyclic Compounds; Male; Oximes; Partial Thromboplastin Time; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Recombinant Proteins; Tissue Plasminogen Activator

1998
Effect of roxatidine bismuth citrate (MX1) against acetylsalicylic acid- and indomethacin-induced gastric mucosal damage in rats.
    Methods and findings in experimental and clinical pharmacology, 1998, Volume: 20, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Drug Combinations; Drug Evaluation, Preclinical; Gastric Mucosa; Indomethacin; Male; Organometallic Compounds; Piperidines; Rats; Rats, Wistar; Stomach Ulcer

1998
Endothelin plays a role in contractions of isolated pig pulmonary vessels induced by diaspirin cross-linked hemoglobin.
    The Journal of laboratory and clinical medicine, 1999, Volume: 133, Issue:5

    Topics: Animals; Aspirin; Endothelin Receptor Antagonists; Endothelin-1; Glycopeptides; Hemoglobins; Isometric Contraction; Muscle, Smooth, Vascular; Nitroarginine; Oligopeptides; Piperidines; Pulmonary Artery; Pulmonary Veins; Receptor, Endothelin A; Receptor, Endothelin B; Swine; Vasoconstrictor Agents

1999
Long-term oral platelet glycoprotein IIb/IIIa receptor antagonism with sibrafiban after acute coronary syndromes: study design of the sibrafiban versus aspirin to yield maximum protection from ischemic heart events post-acute coronary syndromes (SYMPHONY)
    American heart journal, 1999, Volume: 138, Issue:2 Pt 1

    Topics: Angina, Unstable; Aspirin; Clinical Trials, Phase III as Topic; Double-Blind Method; Humans; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs; Randomized Controlled Trials as Topic; Research Design; Syndrome; Treatment Outcome

1999
Comparative antiplatelet effects of aspirin, vapiprost and GR144053, a GPIIb/IIIa antagonist, with a special reference to the role of platelet microaggregates.
    British journal of pharmacology, 1999, Volume: 127, Issue:5

    Topics: Animals; Aspirin; Biphenyl Compounds; Cricetinae; Fibrinolytic Agents; Heptanoic Acids; Male; Piperazines; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombosis

1999
Inhibitory effects of H2-receptor antagonists on platelet function in vitro.
    Human & experimental toxicology, 1999, Volume: 18, Issue:8

    Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cimetidine; Collagen; Famotidine; Female; Heterocyclic Compounds, 1-Ring; Histamine H2 Antagonists; Humans; In Vitro Techniques; Male; Middle Aged; P-Selectin; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Ranitidine; Structure-Activity Relationship

1999
Difficulties with oral platelet glycoprotein IIb/IIIa receptor antagonists.
    Lancet (London, England), 2000, Jan-29, Volume: 355, Issue:9201

    Topics: Administration, Oral; Aspirin; Death, Sudden, Cardiac; Humans; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors

2000
Ex vivo--in vitro interaction between aspirin, clopidogrel, and the glycoprotein IIb/IIIa inhibitors abciximab and SR121566A.
    Clinical pharmacology and therapeutics, 2000, Volume: 67, Issue:3

    Topics: Abciximab; Administration, Oral; Adult; Analysis of Variance; Antibodies, Monoclonal; Aspirin; Benzylamines; Bleeding Time; Clopidogrel; Drug Administration Schedule; Drug Interactions; Fibrinogen; Humans; Immunoglobulin Fab Fragments; Male; Nephelometry and Turbidimetry; P-Selectin; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Reference Values; Thiazoles; Ticlopidine

2000
Effect of aspirin on platelet desaggregation induced by SR121566, a potent GP-IIb/IIIa antagonist.
    Platelets, 2000, Volume: 11, Issue:1

    Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Aspirin; Benzylamines; Blood Flow Velocity; Blood Platelets; Carotid Arteries; Disease Models, Animal; Electric Stimulation; Female; Fibrinolytic Agents; Humans; Male; Oligopeptides; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Rabbits; Recombinant Proteins; Thiazoles; Thrombosis; Thrombospondins; Tissue Plasminogen Activator

2000
Randomisation in the SYMPHONY trial.
    Lancet (London, England), 2000, Oct-28, Volume: 356, Issue:9240

    Topics: Angina, Unstable; Aspirin; Double-Blind Method; Humans; Oximes; Piperidines; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic

2000
How hot is inflammation in acute coronary syndrome?
    European heart journal, 2000, Volume: 21, Issue:24

    Topics: Angina, Unstable; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Disease; Humans; Inflammation; Methylprednisolone; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Randomized Controlled Trials as Topic

2000
Human platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptor.
    European journal of biochemistry, 2001, Volume: 268, Issue:3

    Topics: Adenosine Diphosphate; Amidohydrolases; Arachidonic Acids; Aspirin; Biological Transport; Blood Platelets; Calcium Channel Blockers; Camphanes; Cannabinoid Receptor Modulators; Collagen; Cyclic AMP; Endocannabinoids; Glycerides; Humans; Hydrolysis; Inositol 1,4,5-Trisphosphate; Kinetics; Piperidines; Platelet Activation; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Serotonin; Time Factors

2001
ACE inhibitor reduces cardiovascular events by 22%.
    Indian journal of medical sciences, 2000, Volume: 54, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Cardiovascular Diseases; Humans; Multicenter Studies as Topic; Myocardial Ischemia; Oximes; Piperidines; Platelet Aggregation Inhibitors; Ramipril; Randomized Controlled Trials as Topic

2000
Early statin initiation and outcomes in patients with acute coronary syndromes.
    JAMA, 2002, Jun-19, Volume: 287, Issue:23

    Topics: Acute Disease; Aged; Angina, Unstable; Aspirin; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins; Male; Middle Aged; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors; Proportional Hazards Models; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome

2002
ANALGESIC AND PSYCHOTOMIMETIC PROPERTIES OF DEXOXADROL.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 118

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Biomedical Research; Dioxolanes; Drug Therapy; Female; Hallucinogens; Humans; Pain; Pharmacology; Piperidines; Placebos; Puerperal Disorders; Toxicology

1965
Postmenopausal hormone use in women with acute coronary syndromes.
    Journal of women's health (2002), 2004, Volume: 13, Issue:8

    Topics: Aged; Aspirin; Attitude to Health; Coronary Disease; Estrogen Replacement Therapy; Female; Global Health; Humans; Middle Aged; Myocardial Infarction; Odds Ratio; Oximes; Piperidines; Platelet Aggregation Inhibitors; Postmenopause; Prevalence; Randomized Controlled Trials as Topic; Surveys and Questionnaires; Survival Analysis; Time Factors; Treatment Outcome; Women's Health

2004
Histamine-3 receptor antagonists reduce superoxide anion generation and lipid peroxidation in rat brain homogenates.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:6

    Topics: Animals; Antioxidants; Aspirin; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine Agonists; Imidazoles; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Neurotoxicity Syndromes; Piperidines; Potassium Cyanide; Rats; Rats, Wistar; Receptors, Histamine H3; Superoxides; Thiourea

2005
[Highlights from the American College of Cardiology Annual Scientific Session 2005: March 5-9, 2005, Orlando, Florida].
    Revue medicale suisse, 2005, May-04, Volume: 1, Issue:18

    Topics: Aspirin; Cardiovascular Diseases; Cholesterol, LDL; Clopidogrel; Humans; Hypercholesterolemia; Obesity; Piperidines; Platelet Aggregation Inhibitors; Pyrazoles; Rimonabant; Stroke; Ticlopidine

2005
Prohemorrhagic and bleeding time activities of recombinant tissue plasminogen activator, heparin, aspirin, and a glycoprotein IIb/IIIa antagonist.
    Journal of neurotrauma, 2005, Volume: 22, Issue:11

    Topics: Animals; Aspirin; Bleeding Time; Collagenases; Dose-Response Relationship, Drug; Fibrinolytic Agents; Guinea Pigs; Heparin; Intracranial Hemorrhages; Male; Piperidines; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Propionates; Recombinant Proteins; Tissue Plasminogen Activator; Whole Blood Coagulation Time

2005
Interaction study of aspirin or clopidogrel on pharmacokinetics of donepezil hydrochloride in rats by HPLC-fluorescence detection.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:6

    Topics: Administration, Oral; Animals; Aspirin; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Clopidogrel; Donepezil; Drug Interactions; Fluorescence; Indans; Injections, Intraperitoneal; Male; Molecular Structure; Piperidines; Rats; Rats, Wistar; Ticlopidine

2007
Effects of allyl isothiocyanate from horseradish on several experimental gastric lesions in rats.
    European journal of pharmacology, 2007, Apr-30, Volume: 561, Issue:1-3

    Topics: Alkaloids; Ammonia; Animals; Armoracia; Aspirin; Benzodioxoles; Capsaicin; Dose-Response Relationship, Drug; Ethanol; Food Preservatives; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Isothiocyanates; Male; NG-Nitroarginine Methyl Ester; Omeprazole; Piperidines; Polyunsaturated Alkamides; Prostaglandins; Rats; Rats, Sprague-Dawley; Ruthenium Red; Structure-Activity Relationship

2007
Quantitative evaluation of analgetic action in guinea pigs; morphine, ethyl l-methyl-4-phenylpiperidine-4-carboxylate (demerol) and acetylsalicylic acid.
    Archives internationales de pharmacodynamie et de therapie, 1947, Volume: 74, Issue:3-4

    Topics: Analgesics; Aspirin; Guinea Pigs; Meperidine; Morphine; Piperidines; Salicylates

1947
Aspirin-triggered lipoxin induces CB1-dependent catalepsy in mice.
    Neuroscience letters, 2010, Feb-05, Volume: 470, Issue:1

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acids; Aspirin; Catalepsy; Central Nervous System Agents; Cyclooxygenase Inhibitors; Endocannabinoids; Lipoxins; Male; Mice; Models, Neurological; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Lipoxin; Rimonabant

2010
Celecoxib analogs possessing a N-(4-nitrooxybutyl)piperidin-4-yl or N-(4-nitrooxybutyl)-1,2,3,6-tetrahydropyridin-4-yl nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies.
    Bioorganic & medicinal chemistry letters, 2010, Feb-15, Volume: 20, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Celecoxib; Crystallography, X-Ray; Cyclooxygenase 2 Inhibitors; Humans; Hydrogen-Ion Concentration; Ibuprofen; Inhibitory Concentration 50; Molecular Structure; Nitric Oxide; Nitric Oxide Donors; Piperidines; Prodrugs; Pyrazoles; Rats; Sheep; Structure-Activity Relationship; Sulfonamides

2010
The antinociceptive effect of acetylsalicylic acid is differently affected by a CB1 agonist or antagonist and involves the serotonergic system in rats.
    Life sciences, 2010, Mar-27, Volume: 86, Issue:13-14

    Topics: Analgesics; Animals; Aspirin; Chromatography, High Pressure Liquid; Frontal Lobe; Male; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Rimonabant; Serotonin Plasma Membrane Transport Proteins

2010
2-arachidonyl glycerol activates platelets via conversion to arachidonic acid and not by direct activation of cannabinoid receptors.
    British journal of clinical pharmacology, 2010, Volume: 70, Issue:2

    Topics: Adolescent; Adult; Aged; Arachidonic Acids; Aspirin; Blood Platelets; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Coronary Artery Disease; Endocannabinoids; Glycerides; Humans; Indoles; Male; Middle Aged; Piperidines; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazoles; Young Adult

2010
[Low doses of ketamine have no effect on bispectral index during stable propofol-remifentanil anesthesia].
    Masui. The Japanese journal of anesthesiology, 2012, Volume: 61, Issue:4

    Topics: Acetaminophen; Anesthesia, General; Anesthetics, Intravenous; Aspirin; Chlorpheniramine; Consciousness Monitors; Dextropropoxyphene; Drug Combinations; Female; Humans; Ketamine; Piperidines; Remifentanil

2012
Investigation of piperidine derivatives in ex vivo models of pain and platelet aggregation.
    Archives of pharmacal research, 2012, Volume: 35, Issue:11

    Topics: Analgesics; Animals; Aspirin; Female; Humans; Inhibitory Concentration 50; Male; Mice; Pain; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins; Receptors, Opioid; Structure-Activity Relationship; Thromboxane A2

2012
Anti-thrombotic efficacy of S007-867: Pre-clinical evaluation in experimental models of thrombosis in vivo and in vitro.
    Biochemical pharmacology, 2018, Volume: 148

    Topics: Animals; Aspirin; Blood Coagulation; Chlorides; Clopidogrel; Dose-Response Relationship, Drug; Ferric Compounds; Fibrinolytic Agents; Male; Mice; Piperidines; Platelet Adhesiveness; Platelet Aggregation; Pyrrolidines; Rats; Rats, Sprague-Dawley; Thrombosis

2018
Monoacylglycerol lipase inhibitor, JZL-184, confers neuroprotection in the mice middle cerebral artery occlusion model of stroke.
    Life sciences, 2018, Apr-01, Volume: 198

    Topics: Animals; Aspirin; Behavior, Animal; Benzodioxoles; Brain; Brain Edema; Brain Ischemia; Disease Models, Animal; Edema; Infarction, Middle Cerebral Artery; Inflammation; Interleukin-10; Male; Matrix Metalloproteinase 9; Mice; Monoacylglycerol Lipases; Neuroprotective Agents; Piperidines; Stroke; Tumor Necrosis Factor-alpha

2018
Rates and Risk of Atrial Arrhythmias in Patients Treated With Ibrutinib Compared With Cytotoxic Chemotherapy.
    The American journal of cardiology, 2019, 08-15, Volume: 124, Issue:4

    Topics: Adenine; Age Factors; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antineoplastic Agents; Aspirin; Atrial Fibrillation; Atrial Flutter; Female; Humans; Hypertension; Incidence; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Mantle-Cell; Male; Middle Aged; Multivariate Analysis; Piperidines; Platelet Aggregation Inhibitors; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Risk Factors; Waldenstrom Macroglobulinemia

2019
Risk of Hypoglycemia and Concomitant Use of Repaglinide and Clopidogrel: A Population-Based Nested Case-Control Study.
    Clinical pharmacology and therapeutics, 2019, Volume: 106, Issue:6

    Topics: Aged; Aspirin; Carbamates; Case-Control Studies; Clopidogrel; Drug Interactions; Female; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Middle Aged; Nateglinide; Piperidines; Platelet Aggregation Inhibitors

2019
Inhibition of JAK-STAT and NF-κB signalling systems could be a novel therapeutic target against insulin resistance and type 2 diabetes.
    Life sciences, 2019, Dec-15, Volume: 239

    Topics: Animals; Aspirin; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Interleukin-6; Janus Kinases; Male; NF-kappa B; Piperidines; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Serum Amyloid A Protein; Signal Transduction; STAT Transcription Factors; Tumor Necrosis Factor-alpha

2019