aspirin and oxaprozin

aspirin has been researched along with oxaprozin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199010 (55.56)18.7374
1990's0 (0.00)18.2507
2000's3 (16.67)29.6817
2010's5 (27.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Kumar, M; Sinha, VR; Thareja, S1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Freeland, GR; Hedrich, DA; Northington, RS; Walker, BR1
Amano, T; Kohno, Y; Suwa, T; Suzuki, A; Urano, H1
Bonney, SL; Hedrich, DA; Northington, RS; Walker, BR1
Ahrens, S; Kaiser, PM; Lücker, PW; Venitz, J1
Post, A; Winter, L1
Blazek, EM; Carlson, RP; Gilman, SC; Hodge, TG; Lewis, AJ; O'Neill-Davis, L1
Aihara, H; Amanuma, F; Hashimoto, S; Kameyama, T; Okuyama, S; Orikasa, S; Sakagawa, T; Tarumoto, Y; Tsutsui, Y; Yamada, C1
Hubsher, JA; Kahn, SB1
LeBel, E; Lussier, A; Tétreault, L1
Hubsher, JA; Lanza, FL; Walker, BR1

Reviews

1 review(s) available for aspirin and oxaprozin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for aspirin and oxaprozin

ArticleYear
Renal safety of two analgesics used over the counter: ibuprofen and aspirin.
    Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:4

    Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Double-Blind Method; Humans; Ibuprofen; Kidney; Middle Aged; Osteoarthritis; Oxaprozin; Propionates

1986
Gastric irritation of oxaprozin, a new nonsteroidal, antiinflammatory drug, in comparison to acetylsalicylic acid and indomethacin: a gastric potential difference analysis.
    Methods and findings in experimental and clinical pharmacology, 1987, Volume: 9, Issue:7

    Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastritis; Humans; Indomethacin; Male; Membrane Potentials; Oxaprozin; Propionates; Random Allocation

1987
Double-blind comparison of single oral doses of oxaprozin, aspirin, and placebo for relief of post-operative oral surgery pain.
    The Journal of international medical research, 1983, Volume: 11, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Dentistry, Operative; Double-Blind Method; Female; Humans; Male; Middle Aged; Oxaprozin; Pain, Postoperative; Propionates; Random Allocation

1983
Gastrointestinal blood loss of oxaprozin and aspirin with placebo control.
    Journal of clinical pharmacology, 1982, Volume: 22, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Double-Blind Method; Feces; Gastrointestinal Hemorrhage; Humans; Male; Oxaprozin; Oxazoles; Propionates; Random Allocation

1982
Gastroscopic evaluation of the effect of aspirin and oxaprozin on the gastric mucosa.
    Journal of clinical pharmacology, 1981, Volume: 21, Issue:4

    Topics: Anti-Inflammatory Agents; Aspirin; Female; Gastric Mucosa; Gastroscopy; Humans; Male; Oxaprozin; Oxazoles; Propionates

1981

Other Studies

12 other study(ies) available for aspirin and oxaprozin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Hepatic safety of two analgesics used over the counter: ibuprofen and aspirin.
    Clinical pharmacology and therapeutics, 1988, Volume: 43, Issue:5

    Topics: Alanine Transaminase; Aspirin; Humans; Ibuprofen; Liver; Oxaprozin; Propionates

1988
Comparative studies on the gastrointestinal lesions caused by several nonsteroidal anti-inflammatory agents in rats.
    Agents and actions, 1987, Volume: 21, Issue:1-2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Feces; Gastric Mucosa; Gastrointestinal Hemorrhage; Ibuprofen; Indomethacin; Intestinal Mucosa; Oxaprozin; Phenylpropionates; Propionates; Rats

1987
Effects of oral aspirin and oxaprozin on the development of lupus-like disease in MRL/1 mice.
    Journal of immunopharmacology, 1984, Volume: 6, Issue:1-2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antibodies, Anti-Idiotypic; Aspirin; Autoimmune Diseases; Body Weight; Cyclooxygenase Inhibitors; DNA; Female; Glomerulonephritis; Hyperplasia; Lupus Vulgaris; Lymphoid Tissue; Male; Mice; Oxaprozin; Propionates

1984
[The analgesic and antipyretic effects of a non-steroidal anti-inflammatory drug, oxaprozin, in experimental animals].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1984, Volume: 83, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Temperature; Dogs; Ibuprofen; Indomethacin; Male; Mice; Oxaprozin; Phenylbutazone; Propionates; Rats

1984
Effects of oxaprozin alone or in combination with aspirin on hemostasis and plasma protein binding.
    Journal of clinical pharmacology, 1983, Volume: 23, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Aspirin; Bleeding Time; Blood Proteins; Collagen; Epinephrine; Female; Hemostasis; Humans; Male; Oxaprozin; Platelet Aggregation; Propionates; Protein Binding

1983