aspirin has been researched along with ncx 4040 in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (60.00) | 29.6817 |
| 2010's | 7 (35.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bos, C; de Esch, IJ; Hulsman, N; Jongejan, A; Leurs, R; Medema, JP; Richel, D; Smit, MJ; Wijtmans, M | 1 |
| Angelini, G; Jeremy, JY; Muzaffar, S; Shukla, N | 1 |
| Donati, S; Filippi, S; Forti, G; Lotti, F; Maggi, M; Mancina, R; Marini, M; Mondaini, N; Montorsi, F; Morelli, A; Salonia, A; Vannelli, GB; Vignozzi, L | 1 |
| Amadori, D; Bolla, M; Bravaccini, S; Brigliadori, G; Fabbri, F; Rosetti, M; Tesei, A; Ulivi, P; Vannini, I; Zoli, W | 1 |
| Amadori, D; Bolla, M; Cecconetto, L; Fabbri, F; Leonetti, C; Medri, L; Rosetti, M; Scarsella, M; Tesei, A; Ulivi, P; Zoli, W; Zupi, G | 1 |
| Amadori, D; Bolla, M; Brigliadori, G; Fabbri, F; Rosetti, M; Tesei, A; Ulivi, P; Vannini, I; Zoli, W | 1 |
| Amadori, D; Bolla, M; Fabbri, F; Medri, L; Rosetti, M; Tesei, A; Ulivi, P; Vannini, I; Zoli, W | 1 |
| Chandrasena, RE; Dunlap, T; Sinha, V; Thatcher, GR; Wang, Z | 1 |
| Bobko, A; Bratasz, A; Ignarro, LJ; Khramtsov, VV; Kuppusamy, P; Selvendiran, K; Wasowicz, T | 1 |
| Amadori, D; Bolla, M; Fabbri, F; Leonetti, C; Rosetti, M; Silvestrini, R; Tesei, A; Zoli, W | 1 |
| Abdul-Hay, SO; Chandrasena, RE; Dunlap, T; Hagos, GK; Sinha, V; Thatcher, GR; Wang, H; Wang, Z | 1 |
| Balint, B; Bufan, B; Colić, M; Mojsilović, S; Vasilijić, S; Vucević, D; Vucićević, D | 1 |
| Anzellotti, P; Di Francesco, A; Di Francesco, L; Dovizio, M; Monopoli, A; Patrignani, P; Pistritto, G; Ricciotti, E; Salvatore, T; Sciulli, MG | 1 |
| Baba, K; Harada, T; Hirata, Y; Kawaratani, Y; Nagaoka, Y; Shibano, M; Taniguchi, M; Tanimura, S; Uesato, S; Yasuda, M | 1 |
| Abruzzese, MP; Cippitelli, M; Fionda, C; Molfetta, R; Paolini, R; Ricci, B; Santoni, A; Soriani, A; Zingoni, A | 1 |
| Choe, SH; Choi, EY; Choi, IS; Choi, JI; Hyeon, JY; Kim, SJ; Park, HR | 1 |
| Delgadillo, D; Duarte, LF; Fernández-Ramires, R; Fernández-Soto, R; Jara, JA; Madariaga-Venegas, F; Molina-Berríos, A; Suarez, N; Urzúa, B | 1 |
| López-Contreras, F; López-Muñoz, R; Martin-Martin, A; Molina-Berríos, A; Muñoz-Uribe, M; Pérez-Laines, J; Rivera-Dictter, A | 1 |
| Chen, A; Chinnapaka, S; Munirathinam, G; Zheng, G | 1 |
| Bortner, CD; Sinha, BK; Tokar, EJ | 1 |
1 review(s) available for aspirin and ncx 4040
| Article | Year |
|---|---|
NCX 4040, an NO-donating acetylsalicylic acid derivative: efficacy and mechanisms of action in cancer cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aspirin; Cell Line, Tumor; Humans; Mice; Neoplasms; Nitric Oxide Donors; Nitro Compounds; Organoplatinum Compounds; Pyridines | 2008 |
19 other study(ies) available for aspirin and ncx 4040
| Article | Year |
|---|---|
Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin.
Topics: Antineoplastic Agents; Apoptosis; Aspirin; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Indolequinones; Magnetic Resonance Spectroscopy; Nitric Oxide; Nitric Oxide Donors; Structure-Activity Relationship | 2007 |
Nitroaspirins and morpholinosydnonimine but not aspirin inhibit the formation of superoxide and the expression of gp91phox induced by endotoxin and cytokines in pig pulmonary artery vascular smooth muscle cells and endothelial cells.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Evaluation, Preclinical; Endothelial Cells; Endothelium, Vascular; Enzyme Induction; Epoprostenol; Glycoproteins; Guanylate Cyclase; Interleukin-1; Lipopolysaccharides; Male; Molsidomine; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; Onium Compounds; Pulmonary Artery; Respiratory Distress Syndrome; Superoxides; Sus scrofa; Tumor Necrosis Factor-alpha | 2004 |
Expression and functional activity of phosphodiesterase type 5 in human and rabbit vas deferens.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Androgens; Animals; Aspirin; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Gene Expression Regulation, Enzymologic; Humans; Male; Middle Aged; Myocytes, Smooth Muscle; Nitric Oxide; Nitro Compounds; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rabbits; RNA, Messenger; Vas Deferens | 2005 |
Pro-apoptotic effect of a nitric oxide-donating NSAID, NCX 4040, on bladder carcinoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Aspirin; Cell Cycle; Cell Line, Tumor; Humans; In Situ Nick-End Labeling; Membrane Potentials; Nitric Oxide; Nitro Compounds; Salicylates; Urinary Bladder Neoplasms | 2005 |
Efficacy of a nitric oxide-releasing nonsteroidal anti-inflammatory drug and cytotoxic drugs in human colon cancer cell lines in vitro and xenografts.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Cell Survival; Colonic Neoplasms; Flow Cytometry; Fluorouracil; Humans; Male; Mice; Mice, Nude; Nitric Oxide; Nitro Compounds; Organoplatinum Compounds; Oxaliplatin; Transplantation, Heterologous | 2006 |
Molecular characterization of cytotoxic and resistance mechanisms induced by NCX 4040, a novel NO-NSAID, in pancreatic cancer cell lines.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caspase 9; Cell Cycle; Cell Line, Tumor; Cytotoxins; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Nitric Oxide Donors; Nitro Compounds; Pancreatic Neoplasms; S-Nitroso-N-Acetylpenicillamine; Salicylates | 2006 |
Study of molecular mechanisms of pro-apoptotic activity of NCX 4040, a novel nitric oxide-releasing aspirin, in colon cancer cell lines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Line, Tumor; Colonic Neoplasms; Humans; Membrane Potentials; Mitochondrial Membranes; Molecular Conformation; Nitric Oxide; Nitro Compounds; Nitroprusside | 2007 |
Quinone formation as a chemoprevention strategy for hybrid drugs: balancing cytotoxicity and cytoprotection.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoquinones; Catalysis; Cell Line, Tumor; Cell Survival; Chemoprevention; Cytoprotection; Esterases; Glutathione; Liver; Luciferases; Metabolic Detoxication, Phase II; Mice; Models, Biological; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; Nitro Compounds; Response Elements; Swine | 2007 |
NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols.
Topics: Animals; Antineoplastic Agents; Aspirin; Cell Line, Tumor; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Mice; Mice, Nude; Molecular Structure; Nitro Compounds; Ovarian Neoplasms; Sensitivity and Specificity; Statistics as Topic; Sulfhydryl Compounds; Xenograft Model Antitumor Assays | 2008 |
Nitrates and NO-NSAIDs in cancer chemoprevention and therapy: in vitro evidence querying the NO donor functionality.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Cell Line; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Humans; Macrophages; Mice; Neoplasms; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds | 2008 |
Comparative effects of aspirin and NO-releasing aspirins on differentiation, maturation and function of human monocyte-derived dendritic cells in vitro.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antigens, Differentiation; Apoptosis; Aspirin; Cell Differentiation; Cells, Cultured; Dendritic Cells; Down-Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-10; Interleukin-12 Subunit p40; Interleukin-4; Lipopolysaccharides; Lymphocyte Activation; Monocytes; Nitric Oxide; Nitro Compounds | 2009 |
NCX 4040, a nitric oxide-donating aspirin, exerts anti-inflammatory effects through inhibition of I kappa B-alpha degradation in human monocytes.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Humans; I-kappa B Proteins; Lipopolysaccharides; Monocytes; NF-KappaB Inhibitor alpha; Nitric Oxide Donors; Nitro Compounds; Signal Transduction | 2010 |
New microtubule polymerization inhibitors comprising a nitrooxymethylphenyl group.
Topics: Acetates; Animals; Aspirin; Benzoates; Carbamates; Cell Division; Cell Line, Tumor; Colonic Neoplasms; G2 Phase; Humans; Indoles; Mice; Mice, Nude; Nitrates; Nitro Compounds; Structure-Activity Relationship; Transplantation, Heterologous; Tubulin; Tubulin Modulators; Vincristine | 2011 |
Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation.
Topics: Antigens, Differentiation, T-Lymphocyte; Aspirin; Cell Line, Tumor; DNA Damage; Gene Expression Regulation, Neoplastic; Humans; Ligands; Multiple Myeloma; Nitric Oxide; Nitro Compounds; Receptors, Virus; Triazenes | 2015 |
NCX 4040, a nitric oxide-donating aspirin derivative, inhibits Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages.
Topics: Animals; Aspirin; Enzyme Induction; Heme Oxygenase-1; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; NF-kappa B; Nitric Oxide; Nitro Compounds; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prevotella intermedia; RAW 264.7 Cells; STAT1 Transcription Factor; STAT3 Transcription Factor | 2015 |
Characterization of a novel antibiofilm effect of nitric oxide-releasing aspirin (NCX-4040) on Candida albicans isolates from denture stomatitis patients.
Topics: Antifungal Agents; Aspirin; Bacterial Adhesion; Biofilms; Candida albicans; Dinoprostone; Drug Resistance, Fungal; Fluconazole; Free Radical Scavengers; Humans; Inhibitory Concentration 50; Microbial Viability; Nitro Compounds; Stomatitis, Denture | 2017 |
Reconsidering the Role of Cyclooxygenase Inhibition in the Chemotherapeutic Value of NO-Releasing Aspirins for Lung Cancer.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; Erlotinib Hydrochloride; Humans; Lung Neoplasms; Molecular Structure; Nitric Oxide; Nitro Compounds | 2019 |
Nitro aspirin (NCX4040) induces apoptosis in PC3 metastatic prostate cancer cells via hydrogen peroxide (H
Topics: Apoptosis; Aspirin; Cell Movement; Cell Proliferation; Humans; Hydrogen Peroxide; Male; Nitro Compounds; Oxidants; Oxidative Stress; Prostatic Neoplasms; Tumor Cells, Cultured; Wound Healing | 2019 |
Molecular Mechanisms of Cytotoxicity of NCX4040, the Non-Steroidal Anti-Inflammatory NO-Donor, in Human Ovarian Cancer Cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma, Ovarian Epithelial; Doxorubicin; Female; Humans; Nitro Compounds; Ovarian Neoplasms; Peroxynitrous Acid; Reactive Nitrogen Species; Reactive Oxygen Species | 2022 |