Compounds > aspirin

aspirin and metronidazole

aspirin has been researched along with metronidazole in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19906 (25.00)18.7374
1990's0 (0.00)18.2507
2000's9 (37.50)29.6817
2010's9 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bender, A; Czobor, P; Jelinek, B; Málnási-Csizmadia, A; Peragovics, Á; Simon, Z; Tombor, L; Végner, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abdel-Maksoud, MS; Ali, EMH; Oh, CH1
Gustafsson, BE; Norin, KE1
Begent, RH; Lambert, HP; O'Grady, FW1
Rohte, O2
Eisenberg, NH; Hauser, GJ; Reisner, SH; Stahl, B1
Brzezińska-Wcisło, L; Kralewska, W; Rubisz-Brzezińska, J; Zebracka, T1
Chan, FK; Chan, HL; Chung, SC; Hui, Y; Lai, MS; Lau, JY; Lee, YT; Leung, VK; Leung, WK; Suen, BY; Sung, JJ; Wu, JC1
Alarcón, A; Martínez, JG; Morey, A; Saus, C1
Berg, DE; Dailidiene, D; Gu, Q; Lai, KC; Lam, SK; Wang, WH; Wong, BC; Wong, WM1
Gao, W; Li, J; Tian, Y; Wang, WH; Zhang, XP1
Jang, JY; Jung, HK; Kim, CG; Kim, SG; Lee, H; Lee, HL; Lee, YC; Shin, ES; Shin, WG1

Reviews

3 review(s) available for aspirin and metronidazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances.
    Bioorganic & medicinal chemistry, 2019, 04-01, Volume: 27, Issue:7

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Chemistry, Pharmaceutical; Humans; Inflammation; Neoplasms; Pyrimidines; Structure-Activity Relationship

2019
Maternal medications and breast-feeding.
    Developmental pharmacology and therapeutics, 1983, Volume: 6, Issue:5

    Topics: Anti-Anxiety Agents; Aspirin; Benzodiazepines; Breast Feeding; Chlorpromazine; Contraceptives, Oral; Ergot Alkaloids; Female; Humans; Metronidazole; Milk, Human; Pharmaceutical Preparations; Pregnancy; Thiouracil

1983

Trials

1 trial(s) available for aspirin and metronidazole

ArticleYear
Preventing recurrent upper gastrointestinal bleeding in patients with Helicobacter pylori infection who are taking low-dose aspirin or naproxen.
    The New England journal of medicine, 2001, Mar-29, Volume: 344, Issue:13

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Metronidazole; Naproxen; Omeprazole; Organometallic Compounds; Secondary Prevention; Tetracycline

2001

Other Studies

20 other study(ies) available for aspirin and metronidazole

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Experimental confirmation of new drug-target interactions predicted by Drug Profile Matching.
    Journal of medicinal chemistry, 2013, Nov-14, Volume: 56, Issue:21

    Topics: Algorithms; Angiotensin-Converting Enzyme Inhibitors; Animals; CHO Cells; Cricetulus; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Molecular Conformation; Molecular Targeted Therapy; Peptidyl-Dipeptidase A; Receptors, Dopamine D1; Receptors, Dopamine D2; Structure-Activity Relationship; Substrate Specificity

2013
Development of germfree animal characteristics in conventional rats in antibiotics.
    Acta pathologica et microbiologica Scandinavica. Section B, Microbiology, 1977, Volume: 85B, Issue:1

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Aspirin; Bacitracin; Bile Pigments; Cholestanol; Clofibrate; Colistin; Erythromycin; Feces; Ferrous Compounds; Germ-Free Life; Intestines; Kanamycin; Male; Metronidazole; Neomycin; Oxytetracycline; Penicillin G; Rats; Sorbitol; Sulfathiazoles; Tetracycline

1977
Sensible prescribing. III. Acute otitis media and sore throat.
    The Practitioner, 1975, Volume: 214, Issue:1281

    Topics: Amphotericin B; Ampicillin; Anti-Bacterial Agents; Aspirin; Cephalexin; Drug Prescriptions; Erythromycin; Haemophilus influenzae; Humans; Metronidazole; Nystatin; Otitis Media; Penicillins; Pharyngitis; Staphylococcus; Streptococcus pyogenes

1975
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
    Psychopharmacologia, 1969, Volume: 14, Issue:1

    Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Female; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Psychopharmacology

1969
Studies of the influence of some psychotropic substances on the grooming behaviour of white mice.
    British journal of pharmacology, 1968, Volume: 34, Issue:1

    Topics: Amitriptyline; Animals; Aspirin; Charcoal; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Grooming; Haloperidol; Imipramine; Iproniazid; Metronidazole; Mice; Nortriptyline; Sodium Chloride; Solvents; Tranquilizing Agents

1968
[Problems in the treatment of acne rosacea].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1982, Dec-01, Volume: 35, Issue:22

    Topics: Adult; Aged; Aspirin; Chloroquine; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Male; Metronidazole; Middle Aged; Powders; Prednisone; Rosacea; Tetracyclines

1982
[Crohn's disease and renal amyloidosis. Acute renal failure].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2002, Volume: 22, Issue:4

    Topics: Acetaminophen; Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Amyloidosis; Analgesics, Non-Narcotic; Aspirin; Autoimmune Diseases; Crohn Disease; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Male; Mesalamine; Metronidazole; Renal Dialysis; Substance-Related Disorders

2002
Aspirin inhibits the growth of Helicobacter pylori and enhances its susceptibility to antimicrobial agents.
    Gut, 2003, Volume: 52, Issue:4

    Topics: Amoxicillin; Anti-Bacterial Agents; Aspirin; Clarithromycin; Dose-Response Relationship, Drug; Drug Synergism; Helicobacter pylori; Metronidazole; Microbial Sensitivity Tests; Salicylates

2003
Aspirin increases susceptibility of Helicobacter pylori to metronidazole by augmenting endocellular concentrations of antimicrobials.
    World journal of gastroenterology, 2009, Feb-28, Volume: 15, Issue:8

    Topics: Anti-Infective Agents; Aspirin; Bacterial Outer Membrane Proteins; Bacterial Proteins; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Gene Amplification; Gene Expression Regulation, Bacterial; Helicobacter pylori; Metronidazole; Nitroreductases; Polymerase Chain Reaction; RNA, Bacterial; RNA, Messenger; Tetracycline

2009
[Guidelines for the diagnosis and treatment of Helicobacter pylori infection in Korea, 2013 revised edition].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2013, Volume: 62, Issue:1

    Topics: Amoxicillin; Anti-Bacterial Agents; Aspirin; Bismuth; Breath Tests; Clarithromycin; Gastroesophageal Reflux; Gastroscopy; Helicobacter Infections; Helicobacter pylori; Humans; Lymphoma, B-Cell, Marginal Zone; Metaplasia; Metronidazole; Peptic Ulcer; Proton Pump Inhibitors; Republic of Korea; Stomach Neoplasms; Tetracycline

2013