aspirin and methotrexate

aspirin has been researched along with methotrexate in 102 studies

Research

Studies (102)

Timeframe	Studies, this research(%)	All Research%
pre-1990	30 (29.41)	18.7374
1990's	17 (16.67)	18.2507
2000's	23 (22.55)	29.6817
2010's	31 (30.39)	24.3611
2020's	1 (0.98)	2.80

Authors

Authors	Studies
Apiwattanakul, N; Cha, SH; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Tsuda, M	1
Chan, BS; Lu, R; Schuster, VL	1
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Eraly, SA; Kaler, G; Khandelwal, A; Nagle, M; Nigam, SK; Swaan, PW; Truong, DM	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Hoar, RM; McClain, RM; Woo, DC	1
O'Duffy, JD	1
Kitchen, EA; Meacock, SC	1
Khera, KS	1
Aldred, K; Feldman, M; Lee, E; Lee, M	1
Evans, WE; Fleming, RA; Germain, BF; Seleznick, MJ; Stewart, CF	1
Alarcón-Segovia, D; Kraus, A	1
Kremer, JM	1
Fries, JF; Furst, DE; Lenert, L; Singh, G	1
Ericksen, N; Furst, DE; Hash, L; Herman, RA; Koehnke, R; Porras, A; Riggs, CE; Veng-Pedersen, P	1
Healey, LA; Wilske, KR	1
Christophidis, N; Cosolo, W; Drummer, OH	1
Burnand, MB; Kucera, P	1
Christensen, ML; Cremer, M; Evans, WE; Evens, RP; Stewart, CF	1
Alarcón, GS; Billingsley, LM; Guttadauria, M; Luggen, ME; Polisson, RP; Samuelson, CO; Weiner, SR; Williams, HJ; Willkens, RF; Yarboro, C	1
Christensen, ML; Evans, WE	1
Leon-Perez, R; Maier, WP; Miller, SB	1
Rosenow, EC	1
Rieche, K; Wand, H	1
Rubinstein, H; Szanto, M	1
Colombo, C; Ignarro, LJ	1
Steinberg, AD	1
Maggioni, G	1
Tronnier, H	1
Kalbhen, DA; Lynen, J	1
Arrigoni-Martelli, E; Restelli, A	1
DiMartino, MJ; Misher, A; Walz, DT	1
Di Rosa, M; Papadimitriou, JM; Willoughby, DA	1
Goldman, ID	1
Baker, H	1
Graeme, ML; John, M; Sigg, EB	1
Bennett, A; Berstock, DA; Frank, GJ; Stamford, IF	1
Marco, LA; Randels, PM	1
Chen, TS; Huang, KC; Wenczak, BA	1
Nierenberg, DW	1
Hayes, AH	1
Müller-Suur, R; Seideman, P	1
Burmeister, L; Furst, DE; Koehnke, R; Rooney, TW	1
Watanabe, N	1
Ciccarelli, A; de Crescenzo, G; de Paulis, A; Marinò, D; Marinò, I; Marone, G	1
Karokis, D; Kitas, GD; Raza, K	1
Brañas Fernández, P; Ibáñez Rubio, M; López Robledillo, JC; López Saldaña, D; Rodríuez Serrano, F	1
Jankowska, R; Kraus-Filarska, M; Małolepszy, J; Nadobna, G; Nowak, I; Zak-Nejmark, T	1
Rosenbaum, JT; Smith, JR	1
Orsoni, JG; Pellistri, I; Rama, P; Vincenti, V; Zavota, L	1
Cooper, JA; Eggert, M; Lock, BJ	1
Hull, R; Marshall, RW; Marshall, VJ	1
Alivernini, S; De Santis, M; Ferraccioli, G; Loperfido, F; Verrillo, A; Zoli, A	1
Degraeve, F; Fraisse, TC; Le Quellec, A; Rivière, S	1
Beaugerie, L; Cosnes, J; Daniel, F; Marteau, P; Seksik, P	1
Yazici, Y	1
Hersh, EV; Moore, PA; Pinto, A	1
Hall, JK	1
Al Qahtani, M; Alzahrani, M; Haider, A; Palker, V; Saeed, AB; Salih, SB	1
Aslan, I; Aydin, S; Buyukozturk, S; Colakoglu, B; Dal, M; Gelincik, A	1
Albertini, F; Ballardini, G; Bassi, P; Briganti, E; Casadio, C; Casolari, S; De Angelis, P; De Donà, D; Gaddoni, G; Menni, B; Patrizi, A; Savoia, F; Spadola, G; Zanotti, M	1
Jacobs, AM	1
Balsalobre Aznar, J; Porta-Etessam, J	1
Chakarbarty, B; Jain, R; Juneja, M	1
Frohman, L; Mesquida, M; Pelegrín, L; Rey, A; Sánchez-Dalmau, B	1
Colebatch, AN; Edwards, CJ; Marks, JL	1
Borchers, AT; Gershwin, ME	1
Dimic, A; Liu, Y; Mease, P; Raskina, T; Shalamberidze, L; Smith, J; Strand, V; Xu, LA	1
Besada, E; Nossent, JC	1
Colebatch, AN; Edwards, CJ; Marks, JL; van der Heijde, DM	1
Burgner, D; Kuijpers, TW; Kuipers, IM; Tacke, CE	1
Lindberg, M	1
Chang, HY; Chang, PY; Chen, TL; Cheng, AL; Chuang, SE; Hsieh, MC; Lai, GM; Lee, LM; Yan, KH; Yan, MD; Yao, CJ	1
Anelli, MG; Cacciapaglia, F; Covelli, M; Iannone, F; Lapadula, G; Rinaldi, A; Scioscia, C; Serafino, L	1
El-Kimary, EI; Maher, HM; Ragab, MA	1
Epafra, E; Janabi, M; Kazahura, P; Lyimo, F; Nicholaus, P; Pallangyo, P	1
Boerrigter, E; Crul, M	1
Deuter, C; Kötter, I; Stübiger, N	1
Gupta, A; Hopyan, S; Koo, A; Renzi, S; Taylor, T; Tsimerman, E	1
Chistiakov, DA; Grechko, AV; Melnichenko, AA; Myasoedova, VA; Orekhov, AN	1
Bonnotte, B; Ghesquière, T; Greigert, H; Samson, M	1
Howell, K; Romanick, M; Vasquez, MR	1

Reviews

22 review(s) available for aspirin and methotrexate

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Severe rheumatoid arthritis: current options in drug therapy. Geriatrics, 1990, Volume: 45, Issue:12 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Arthritis, Rheumatoid; Aspirin; Clinical Protocols; Cyclosporins; Drug Therapy, Combination; Fatty Acids, Omega-3; Glucosamine; Humans; Hydroxychloroquine; Interferon-gamma; Methotrexate; Ribose	1990
Drug interactions with methotrexate. The Journal of rheumatology. Supplement, 1985, Volume: 12 Suppl 12 Topics: Absorption; Anti-Bacterial Agents; Arthritis, Rheumatoid; Aspirin; Biological Transport; Cell Membrane; Cisplatin; Dose-Response Relationship, Drug; Drug Interactions; Folic Acid; Humans; Kidney Tubules; Methotrexate; Probenecid; Protein Binding; Salicylates; Serum Albumin; Sulfamethoxazole; Sulfonamides; Tissue Distribution	1985
The spectrum of drug-induced pulmonary disease. Annals of internal medicine, 1972, Volume: 77, Issue:6 Topics: Adrenal Cortex Hormones; Aerosols; Analgesics; Aspirin; Autonomic Agents; Bleomycin; Busulfan; Contraceptives, Oral; Cyclophosphamide; Dextropropoxyphene; Drug Hypersensitivity; Heroin; Humans; Lung Diseases; Lupus Erythematosus, Systemic; Methadone; Methotrexate; Mineral Oil; Nitrofurantoin; Oxygen Inhalation Therapy; Paraquat; Pituitary Gland, Posterior; Pleural Effusion; Sulfonamides; Tissue Extracts	1972
An approach to the use of immunosuppressive drugs in nonmalignant diseases. The Journal of allergy and clinical immunology, 1973, Volume: 52, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chlorambucil; Cyclophosphamide; Granulomatosis with Polyangiitis; Hepatitis; Humans; Immunosuppressive Agents; Liver Cirrhosis; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Mice; Mice, Inbred NZB; Multiple Sclerosis; Nephritis; Nephrosis; Nitrogen Mustard Compounds; Penicillins; Psoriasis; Uveitis, Anterior	1973
[Update drug therapy of juvenile rheumatoid arthritis]. Ryumachi. [Rheumatism], 1996, Volume: 36, Issue:4 Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Aspirin; Humans; Immunosuppressive Agents; Methotrexate; Prednisolone	1996
Infiltrative lung disease due to noncytotoxic agents. Clinics in chest medicine, 2004, Volume: 25, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Aspirin; Humans; Hydrochlorothiazide; Iatrogenic Disease; Kidney Diseases; Lung Diseases; Lung Diseases, Interstitial; Methotrexate; Narcotics; Organogold Compounds; Syndrome	2004
[Refractory proctitis]. Gastroenterologie clinique et biologique, 2007, Volume: 31, Issue:4 Topics: Administration, Oral; Adrenal Cortex Hormones; Algorithms; Anesthetics, Local; Antibodies, Monoclonal; Aspirin; Azathioprine; Biopsy; Cyclosporine; Drug Therapy, Combination; Escherichia coli; Forecasting; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Infliximab; Lidocaine; Methotrexate; Nicotine; Patient Compliance; Probiotics; Proctitis; Randomized Controlled Trials as Topic; Rectum; Suppositories; Time Factors	2007
Vasculitis update, 2007. Bulletin of the NYU hospital for joint diseases, 2007, Volume: 65, Issue:3 Topics: Adrenal Cortex Hormones; Anticoagulants; Antirheumatic Agents; Aspirin; Cyclophosphamide; Giant Cell Arteritis; Granulomatosis with Polyangiitis; Humans; Methotrexate	2007
Adverse drug interactions involving common prescription and over-the-counter analgesic agents. Clinical therapeutics, 2007, Volume: 29 Suppl Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Interactions; Ethanol; Health Status; Humans; Lithium Compounds; Methotrexate; Nonprescription Drugs; Selective Serotonin Reuptake Inhibitors; Warfarin	2007
Giant-cell arteritis. Current opinion in ophthalmology, 2008, Volume: 19, Issue:6 Topics: Aspirin; Blood Sedimentation; C-Reactive Protein; Fibrinogen; Fluorodeoxyglucose F18; Giant Cell Arteritis; Glucocorticoids; Humans; Interleukin-6; Magnetic Resonance Angiography; Methotrexate; Platelet Count; Radiopharmaceuticals; Ultrasonography, Doppler, Color	2008
Perioperative management of the patient with rheumatoid arthritis. Clinics in podiatric medicine and surgery, 2010, Volume: 27, Issue:2 Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Cervical Vertebrae; Clinical Laboratory Techniques; Glucocorticoids; Humans; Immobilization; Methotrexate; Penicillamine; Perioperative Care; Platelet Aggregation Inhibitors; Postoperative Complications; Radiography; Spinal Diseases; Tumor Necrosis Factor-alpha; Venous Thrombosis	2010
[Temporal arteritis: treatment controversies]. Neurologia (Barcelona, Spain), 2010, Volume: 25, Issue:7 Topics: Aspirin; Benzamides; Giant Cell Arteritis; Glucocorticoids; Humans; Imatinib Mesylate; Immunosuppressive Agents; Methotrexate; Middle Aged; Optic Neuropathy, Ischemic; Piperazines; Platelet Aggregation Inhibitors; Protein Kinase Inhibitors; Pyrimidines	2010
Safety of non-steroidal anti-inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving methotrexate for inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, other spondyloarthritis). The Cochrane database of systematic reviews, 2011, Nov-09, Issue:11 Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Aspirin; Drug Interactions; Drug Therapy, Combination; Humans; Methotrexate; Randomized Controlled Trials as Topic; Spondylarthritis; Spondylitis, Ankylosing	2011
Giant cell arteritis: a review of classification, pathophysiology, geoepidemiology and treatment. Autoimmunity reviews, 2012, Volume: 11, Issue:6-7 Topics: Aorta; Aortic Aneurysm; Aspirin; Azathioprine; Dendritic Cells; Female; Giant Cell Arteritis; Humans; Macrophages; Magnetic Resonance Angiography; Male; Methotrexate; Positron-Emission Tomography; Sex Factors; T-Lymphocytes; Temporal Arteries; Ultrasonography	2012
Ultrasonographic resolution of the vessel wall oedema with modest clinical improvement in a large-vessel vasculitis patient treated with tocilizumab. Clinical rheumatology, 2012, Volume: 31, Issue:8 Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Aspirin; Biopsy; Drug Resistance; Drug Therapy, Combination; Edema; Giant Cell Arteritis; Humans; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Prednisolone; Temporal Arteries; Ultrasonography, Doppler, Duplex	2012
Safety of nonsteroidal antiinflammatory drugs and/or paracetamol in people receiving methotrexate for inflammatory arthritis: a Cochrane systematic review. The Journal of rheumatology. Supplement, 2012, Volume: 90 Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; Aspirin; Contraindications; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Evidence-Based Medicine; Expert Testimony; Humans; International Cooperation; Methotrexate; Pain; Pain Management; Randomized Controlled Trials as Topic	2012
Management of acute and refractory Kawasaki disease. Expert review of anti-infective therapy, 2012, Volume: 10, Issue:10 Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Murine-Derived; Aspirin; Chemotherapy, Adjuvant; Coronary Aneurysm; Cyclosporine; Enzyme Inhibitors; Humans; Immunoglobulins, Intravenous; Methotrexate; Mucocutaneous Lymph Node Syndrome; Rituximab; Tumor Necrosis Factor-alpha	2012
[Ocular involvement in rheumatoid arthritis, connective tissue diseases and vasculitis]. Zeitschrift fur Rheumatologie, 2017, Volume: 76, Issue:8 Topics: Acute Disease; Adrenal Cortex Hormones; Arthritis, Rheumatoid; Aspirin; Collagen Diseases; Cross-Sectional Studies; Eye Diseases; Giant Cell Arteritis; Humans; Immunosuppressive Agents; Keratoconjunctivitis Sicca; Lupus Erythematosus, Systemic; Methotrexate; Retinal Diseases; Scleritis; Uveitis, Anterior; Vascular Diseases	2017
Concomitant Administration of High-dose Methotrexate and Low-dose Aspirin Without Any Delay in Methotrexate Clearance in a Patient With Osteosarcoma: A Case Report and Review of the Literature. Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:6 Topics: Aspirin; Bone Neoplasms; Child; Glomerular Filtration Rate; Humans; Male; Methotrexate; Osteosarcoma	2018
Potential of anti-inflammatory agents for treatment of atherosclerosis. Experimental and molecular pathology, 2018, Volume: 104, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Aspirin; Atherosclerosis; Colchicine; Cyclooxygenase 2 Inhibitors; Cytokines; Humans; Inflammation; Leukotrienes; Methotrexate; Molecular Targeted Therapy; Phospholipase A2 Inhibitors; Signal Transduction	2018
[Treatment of giant cell arteritis]. Presse medicale (Paris, France : 1983), 2019, Volume: 48, Issue:9 Topics: Abatacept; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Aspirin; Azathioprine; Drug Administration Schedule; Giant Cell Arteritis; Glucocorticoids; Humans; Immunosuppressive Agents; Leflunomide; Methotrexate; Prednisone; Ustekinumab	2019

Trials

5 trial(s) available for aspirin and methotrexate

Article	Year
Aspirin, hydroxychloroquine, and hepatic enzyme abnormalities with methotrexate in rheumatoid arthritis. Arthritis and rheumatism, 1990, Volume: 33, Issue:11 Topics: Alanine Transaminase; Analysis of Variance; Arthritis, Rheumatoid; Aspartate Aminotransferases; Aspirin; Canada; Drug Therapy, Combination; Follow-Up Studies; Humans; Hydroxychloroquine; Liver; Methotrexate; Product Surveillance, Postmarketing; Prospective Studies; Regression Analysis; United States	1990
Comparison of low-dose oral pulse methotrexate and placebo in the treatment of rheumatoid arthritis. A controlled clinical trial. Arthritis and rheumatism, 1985, Volume: 28, Issue:7 Topics: Administration, Oral; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged	1985
Aspirin is not associated with more toxicity than other nonsteroidal antiinflammatory drugs in patients with rheumatoid arthritis treated with methotrexate. The Journal of rheumatology, 1993, Volume: 20, Issue:8 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Prednisone; Retrospective Studies	1993
A phase II, double-blind, randomised, placebo-controlled study of BMS945429 (ALD518) in patients with rheumatoid arthritis with an inadequate response to methotrexate. Annals of the rheumatic diseases, 2012, Volume: 71, Issue:7 Topics: Analgesics; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Double-Blind Method; Drug Substitution; Drug Therapy, Combination; Female; Folic Acid; Health Status; Humans; Injections, Intravenous; Joints; Male; Methotrexate; Middle Aged; Prednisolone; Remission Induction; Severity of Illness Index; Treatment Failure; Treatment Outcome	2012
Lipid profile of rheumatoid arthritis patients treated with anti-tumor necrosis factor-alpha drugs changes according to disease activity and predicts clinical response. Drug development research, 2014, Volume: 75 Suppl 1 Topics: Adalimumab; Adrenal Cortex Hormones; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Certolizumab Pegol; Cholesterol; Cyclosporine; Drug Therapy, Combination; Etanercept; Female; Humans; Hydroxychloroquine; Immunoglobulin Fab Fragments; Immunoglobulin G; Infliximab; Lipid Metabolism; Male; Methotrexate; Middle Aged; Polyethylene Glycols; Receptors, Tumor Necrosis Factor; Severity of Illness Index; Sulfasalazine; Treatment Outcome; Triglycerides; Tumor Necrosis Factor-alpha	2014

Other Studies

75 other study(ies) available for aspirin and methotrexate

Article	Year
Identification of multispecific organic anion transporter 2 expressed predominantly in the liver. FEBS letters, 1998, Jun-12, Volume: 429, Issue:2 Topics: Animals; Blotting, Northern; Carrier Proteins; Ion Transport; Liver; Membrane Proteins; Organic Anion Transporters, Sodium-Independent; Rats; Salicylates; Salicylic Acid; Substrate Specificity; Xenopus laevis	1998
Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C. The American journal of physiology, 1999, Volume: 276, Issue:2 Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; DNA, Complementary; HeLa Cells; Humans; Kidney; Molecular Sequence Data; p-Aminohippuric Acid; Protein Kinase C; Rats; Substrate Specificity; Tissue Distribution	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. The Journal of biological chemistry, 2007, Aug-17, Volume: 282, Issue:33 Topics: Binding Sites; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Structure; Organic Anion Transport Protein 1; Organic Anion Transporters; Static Electricity; Substrate Specificity	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Potentiation of methotrexate embryolethality by aspirin in rats. Teratology, 1978, Volume: 17, Issue:1 Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Body Weight; Drug Synergism; Embryo, Mammalian; Female; Fetal Death; Methotrexate; Pregnancy; Rats; Tissue Distribution	1978
Psoriatic arthritis. Postgraduate medicine, 1977, Volume: 61, Issue:1 Topics: Adolescent; Adult; Arthritis; Aspirin; Female; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Radiography; Spondylitis	1977
Some effects of non-steroidal anti-inflammatory drugs on leucocyte migration. Agents and actions, 1976, Volume: 6, Issue:1-3 Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Cell Movement; Edema; Fenoprofen; Ibuprofen; Indomethacin; Ketoprofen; Leukocytes; Male; Methotrexate; Naproxen; Phenylbutazone; Pleurisy; Rats	1976
Teratogenicity studies with methotrexate, aminopterin, and acetylsalicylic acid in domestic cats. Teratology, 1976, Volume: 14, Issue:1 Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Aspirin; Cats; Female; Methotrexate; Teratogens; Time Factors	1976
Aspirin-induced acute gastric mucosal injury is a neutrophil-dependent process in rats. The American journal of physiology, 1992, Volume: 263, Issue:6 Pt 1 Topics: Acute Disease; Animals; Aspirin; Blood Cell Count; Eicosanoids; Gastric Mucosa; Immune Sera; Leucovorin; Male; Methotrexate; Neutropenia; Neutrophils; Rats; Rats, Sprague-Dawley	1992
Drugs for rheumatoid arthritis. The Medical letter on drugs and therapeutics, 1991, Jul-12, Volume: 33, Issue:848 Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Azathioprine; Costs and Cost Analysis; Drugs, Investigational; Humans; Hydroxychloroquine; Methotrexate; Monitoring, Physiologic; Organogold Compounds; Penicillamine; Sulfasalazine	1991
Aspirin alters methotrexate disposition in rheumatoid arthritis patients. Arthritis and rheumatism, 1991, Volume: 34, Issue:12 Topics: Administration, Oral; Adult; Arthritis, Rheumatoid; Aspirin; Blood Proteins; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Kidney; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Protein Binding	1991
Fever in adult onset Still's disease. Response to methotrexate. The Journal of rheumatology, 1991, Volume: 18, Issue:6 Topics: Adolescent; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Aspirin; Dose-Response Relationship, Drug; Female; Fever; Humans; Male; Methotrexate; Middle Aged; Prednisone	1991
Effect of aspirin and sulindac on methotrexate clearance. Journal of pharmaceutical sciences, 1990, Volume: 79, Issue:9 Topics: Arthritis, Rheumatoid; Aspirin; Drug Interactions; Female; Humans; Male; Methotrexate; Sulindac	1990
Challenging the therapeutic pyramid: a new look at treatment strategies for rheumatoid arthritis. The Journal of rheumatology. Supplement, 1990, Volume: 25 Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Methotrexate; Prednisolone; Rheumatology	1990
Comparison of high-performance liquid chromatography and the Abbott fluorescent polarization radioimmunoassay in the measurement of methotrexate. Journal of chromatography, 1989, Sep-29, Volume: 494 Topics: Administration, Oral; Aspirin; Chromatography, High Pressure Liquid; Drug Interactions; Fluorescence Polarization; Half-Life; Humans; Indomethacin; Injections, Intravenous; Methotrexate; Radioimmunoassay; Reagent Kits, Diagnostic; Rheumatic Diseases	1989
Routine teratogenicity test that uses chick embryos in vitro. Teratogenesis, carcinogenesis, and mutagenesis, 1987, Volume: 7, Issue:5 Topics: Animal Testing Alternatives; Animals; Aspirin; Chick Embryo; In Vitro Techniques; Methotrexate; Saccharin; Teratogens	1987
Influence of concomitant aspirin or prednisone on methotrexate synovial fluid concentration. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1 Topics: Animals; Aspirin; Blood Proteins; Dogs; Drug Interactions; Methotrexate; Prednisone; Protein Binding; Synovial Fluid	1987
Pneumonitis during low-dose methotrexate therapy. Archives of internal medicine, 1986, Volume: 146, Issue:3 Topics: Arthritis, Rheumatoid; Aspirin; Drug Interactions; Humans; Methotrexate; Pneumonia	1986
Influence of cytostatics on aggregation and adenine nucleotides of platelets. Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 53 Topics: Adenine Nucleotides; Adenosine Diphosphate; Amidines; Antineoplastic Agents; Aspirin; Bleomycin; Blood Platelets; Cell Membrane; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Glyoxal; Humans; Hydrazones; Methotrexate; Neoplasms; Platelet Adhesiveness; Triaziquone; Vinca Alkaloids	1972
Reiter's syndrome treated with methotrexate. IMJ. Illinois medical journal, 1972, Volume: 142, Issue:5 Topics: Adult; Arthritis, Reactive; Aspirin; Humans; Male; Methotrexate; Phenylbutazone; Remission, Spontaneous; Tetracycline	1972
Enzyme release from guinea-pig polymorphonuclear leucocyte lysosomes inhibited in vitro by anti-inflammatory drugs. Nature: New biology, 1972, Oct-04, Volume: 239, Issue:92 Topics: Animals; Anti-Inflammatory Agents; Aspirin; Chloroquine; Cyclophosphamide; Depression, Chemical; Flufenamic Acid; Galactosidases; Glucuronidase; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Indomethacin; Leukocytes; Lysosomes; Methotrexate; Phenylbutazone; Sulfatases	1972
[Therapy of rheumatoid disease in the child]. Recenti progressi in medicina, 1972, Volume: 53, Issue:4 Topics: Arthritis, Juvenile; Aspirin; Child; Chlorambucil; Diet Therapy; Gold; Humans; Methotrexate; Prednisone	1972
Psoriatic arthritis. JAMA, 1973, Apr-30, Volume: 224, Issue:5 Suppl Topics: Arthritis; Aspirin; Glucocorticoids; Gold; Humans; Methotrexate; Psoriasis	1973
[Therapy of mycosis fungoides]. Minerva medica, 1973, Dec-26, Volume: 64, Issue:93 Topics: Aspirin; Chloroquine; Cyclophosphamide; Humans; Methotrexate; Mycosis Fungoides; Prednisone; Sunlight; Ultraviolet Rays; Vinblastine	1973
[Effect of some anti-inflammatory drugs on the ATP-content and cell proliferation of neoplastic mast cells in vitro]. Arzneimittel-Forschung, 1968, Volume: 18, Issue:12 Topics: Adenosine Triphosphate; Amides; Aminopyrine; Anti-Inflammatory Agents; Aspirin; Benzimidazoles; Benzoates; Cell Division; Chloroquine; Culture Techniques; Depression, Chemical; Dinitrophenols; Indomethacin; Mast-Cell Sarcoma; Methotrexate; Naphthalenes; ortho-Aminobenzoates; Oxyphenbutazone; Phenylbutazone; Salicylamides; Sodium Salicylate; Stimulation, Chemical	1968
Release of lysosomal enzymes in experimental inflammations: effects of anti-inflammatory drugs. European journal of pharmacology, 1972, Volume: 19, Issue:2 Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Aspirin; Betamethasone; Carrageenan; Dexamethasone; Edema; Female; Glucuronidase; Hexosaminidases; Indomethacin; Inflammation; Lysosomes; Methotrexate; Nystatin; Phenylbutazone; Prednisolone; Rats; Time Factors	1972
Adjuvant-induced arthritis in rats. II. Drug effects on physiologic, biochemical and immunologic parameters. The Journal of pharmacology and experimental therapeutics, 1971, Volume: 178, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Antibodies; Arthritis; Aspirin; Body Weight; Cyclophosphamide; Disease Models, Animal; Freund's Adjuvant; Hindlimb; Immunosuppressive Agents; Indomethacin; Male; Methotrexate; Muramidase; Phenylbutazone; Prednisolone; Rats	1971
A histopathological and pharmacological analysis of the mode of action of nonsteroidal anti-inflammatory drugs. The Journal of pathology, 1971, Volume: 105, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Aspirin; Bone Marrow; Carrageenan; Edema; Indomethacin; Leukocytes; Macrophages; Male; Mefenamic Acid; Methotrexate; Phagocytosis; Phenylbutazone; Pleurisy; Radiation Effects; Rats; Thymidine; Tritium; Turpentine	1971
The characteristics of the membrane transport of amethopterin and the naturally occurring folates. Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186 Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Aspirin; Azides; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Cell Membrane; Cells, Cultured; Chlorides; Erythrocytes; Folic Acid; Humans; Kinetics; Leukemia L1210; Methotrexate; Mice; Nitrates; Organophosphorus Compounds; Phosphates; Rabbits; Sulfates; Time Factors	1971
Intermittent high dose oral methotrexate therapy in psoriasis. The British journal of dermatology, 1970, Volume: 82, Issue:1 Topics: Adult; Aged; Aspirin; Ataxia; Colitis; Female; Hematologic Diseases; Humans; Male; Methotrexate; Middle Aged; Psoriasis; Stevens-Johnson Syndrome; Time Factors; Vomiting	1970
Induction of periarthritis by oral administration of 6-sulfanilamidoindazole and its treatment in rats. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:1 Topics: Animals; Aspirin; Chloroquine; Cloxacillin; Hydralazine; Hydrocortisone; Indomethacin; Male; Mercaptopurine; Methotrexate; Morphine; ortho-Aminobenzoates; Oxyphenbutazone; Paramethasone; Periarthritis; Phenylbutazone; Rats; Sulfinpyrazone; Sulfonamides	1967
Decrease in aspirin-induced gastric mucosal damage in rats by oral administration of the cytotoxic drugs melphalan and methotrexate. The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:8 Topics: Animals; Aspirin; Female; Gastric Mucosa; Male; Melphalan; Methotrexate; Prostaglandins; Rats	1980
Drug interactions in alcoholic patients. The Hillside journal of clinical psychiatry, 1981, Volume: 3, Issue:1 Topics: Alcoholism; Anesthetics; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Antihypertensive Agents; Antipsychotic Agents; Aspirin; Disulfiram; Drug Interactions; Ethanol; Ethylene Dibromide; Hemorrhage; Humans; Hypoglycemia; Hypotension; Methotrexate; Narcotics; Procarbazine; Sulfonylurea Compounds; Warfarin	1981
Transport of methotrexate in cortical slices of monkey kidney: effect of organic anions and vincristine. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:3 Topics: 2,4-Dinitrophenol; Aminohippuric Acids; Animals; Aspirin; Biological Transport; Dinitrophenols; Female; Folic Acid; Kidney Cortex; Kinetics; Leucovorin; Macaca fascicularis; Macaca mulatta; Male; Methotrexate; Ouabain; p-Aminohippuric Acid; Vincristine	1983
Competitive inhibition of methotrexate accumulation in rabbit kidney slices by nonsteroidal anti-inflammatory drugs. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1 Topics: 2,4-Dinitrophenol; Animals; Anti-Inflammatory Agents; Aspirin; Binding, Competitive; Dinitrophenols; Kidney Cortex; Kinetics; Methotrexate; Nitrogen; p-Aminohippuric Acid; Probenecid; Rabbits	1983
Therapeutic implications of drug interactions with acetaminophen and aspirin. Archives of internal medicine, 1981, Feb-23, Volume: 141, Issue:3 Spec No Topics: Acetaminophen; Antacids; Anticoagulants; Aspirin; Drug Interactions; Humans; Methotrexate; Propantheline; Sulfinpyrazone	1981
Renal effects of aspirin and low dose methotrexate in rheumatoid arthritis. Annals of the rheumatic diseases, 1993, Volume: 52, Issue:8 Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Chromium Radioisotopes; Drug Therapy, Combination; Edetic Acid; Female; Humans; Kidney; Kidney Glomerulus; Kidney Tubules; Male; Methotrexate; Middle Aged	1993
Human synovial mast cells. II. Heterogeneity of the pharmacologic effects of antiinflammatory and immunosuppressive drugs. Arthritis and rheumatism, 1997, Volume: 40, Issue:3 Topics: Adenosine; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chymases; Cyclosporine; Diclofenac; Histamine Release; Humans; Immunoglobulin E; Immunosuppressive Agents; Leukotriene C4; Mast Cells; Methotrexate; Middle Aged; Polyenes; Prostaglandins D; Rheumatic Diseases; Serine Endopeptidases; Sirolimus; Substance P; Sulfonamides; Synovial Membrane; Tacrolimus; Tryptases	1997
Cogan's syndrome with Takayasu's arteritis. British journal of rheumatology, 1998, Volume: 37, Issue:4 Topics: Angiography; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Aspirin; Cyclophosphamide; Epoprostenol; Female; Hearing Loss, Sensorineural; Humans; Injections, Intravenous; Keratitis; Methotrexate; Middle Aged; Platelet Aggregation Inhibitors; Prednisolone; Recurrence; Subclavian Artery; Takayasu Arteritis	1998
[CINCA syndrome. An infrequent systemic process]. Anales espanoles de pediatria, 1998, Volume: 49, Issue:1 Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Arthropathy, Neurogenic; Aspirin; Child; Humans; Male; Methotrexate; Prednisone; Syndrome	1998
[Effects of anti-inflammatory drugs on adhesion and migration of lymphocytes]. Polskie Archiwum Medycyny Wewnetrznej, 1999, Volume: 101, Issue:4 Topics: Adult; Anti-Inflammatory Agents; Antigens, CD; Aspirin; Cell Adhesion; Cell Movement; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Lymphocytes; Male; Methotrexate; Reference Values; Transforming Growth Factor beta	1999
Case reports and small case series: scleritis occurring in association with Takayasu disease. Archives of ophthalmology (Chicago, Ill. : 1960), 2001, Volume: 119, Issue:5 Topics: Adult; Aorta, Thoracic; Aortography; Aspirin; Blood Pressure; Drug Therapy, Combination; Female; Folic Acid; Humans; Methotrexate; Methylprednisolone; Prednisone; Scleritis; Takayasu Arteritis; Visual Acuity	2001
Cogan syndrome in children: early diagnosis and treatment is critical to prognosis. American journal of ophthalmology, 2004, Volume: 137, Issue:4 Topics: Amblyopia; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Autoimmune Diseases; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Fludrocortisone; Hearing Loss, Sensorineural; Humans; Immunosuppressive Agents; Keratitis; Male; Methotrexate; Prognosis; Syndrome; Vasculitis; Vision, Low	2004
Disease-modifying anti-rheumatic drugs are only one of a number of potential causes of myelosuppression: a careful drug history is necessary to elucidate the cause of an adverse event. Rheumatology (Oxford, England), 2006, Volume: 45, Issue:3 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Infective Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Female; Humans; Lansoprazole; Methotrexate; Omeprazole; Pancytopenia	2006
Lupus anticoagulant and ischemic myocardial microangiopathy in rheumatoid arthritis. Nature clinical practice. Cardiovascular medicine, 2006, Volume: 3, Issue:6 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Clopidogrel; Echocardiography; Humans; Interleukin 1 Receptor Antagonist Protein; Lupus Coagulation Inhibitor; Male; Methotrexate; Middle Aged; Myocardial Ischemia; Platelet Aggregation Inhibitors; Prednisolone; Radionuclide Imaging; Sialoglycoproteins; Ticlopidine	2006
[Evolution and prognosis of adult onset Still's disease. A monocentric study of 17 patients]. La Revue de medecine interne, 2006, Volume: 27, Issue:9 Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Aspirin; Cohort Studies; Data Interpretation, Statistical; Female; Follow-Up Studies; Humans; Male; Methotrexate; Middle Aged; Prognosis; Prospective Studies; Retrospective Studies; Still's Disease, Adult-Onset; Time Factors; Treatment Outcome	2006
Primary CNS lymphoma presenting as fever of unknown origin. Journal of neuro-oncology, 2009, Volume: 93, Issue:3 Topics: Antihypertensive Agents; Antineoplastic Agents; Antitubercular Agents; Aspirin; Brain Neoplasms; Cranial Irradiation; Diagnosis, Differential; Fatal Outcome; Fever of Unknown Origin; Humans; Hypertension; Indapamide; Lymphoma; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Tetrazoles; Tuberculosis; Valine; Valsartan	2009
Methotrexate: can it be a choice for nasal polyposis in aspirin exacerbated respiratory disease? The Journal of asthma : official journal of the Association for the Care of Asthma, 2009, Volume: 46, Issue:10 Topics: Adrenal Cortex Hormones; Aged; Aspirin; Asthma; Drug Hypersensitivity; Endoscopy; Female; Forced Expiratory Volume; Humans; Methotrexate; Methylprednisolone; Middle Aged; Nasal Cavity; Nasal Polyps; Paranasal Sinuses; Tomography, X-Ray Computed	2009
A case of aseptic pleuropericarditis in a patient with chronic plaque psoriasis under methotrexate therapy. Dermatology online journal, 2010, Feb-15, Volume: 16, Issue:2 Topics: Anti-Inflammatory Agents; Aspirin; Chronic Disease; Colchicine; Dermatologic Agents; Drug Therapy, Combination; Humans; Male; Methotrexate; Middle Aged; Pericarditis; Pleurisy; Psoriasis	2010
Atypical Cogan syndrome mimicking acute rheumatic fever. Indian pediatrics, 2011, Volume: 48, Issue:7 Topics: Anti-Inflammatory Agents; Aspirin; Autoimmune Diseases; Child; Cogan Syndrome; Diagnosis, Differential; Humans; Male; Methotrexate; Prednisolone; Rheumatic Fever	2011
Blind runner. Survey of ophthalmology, 2012, Volume: 57, Issue:5 Topics: Adult; Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Aspirin; Bevacizumab; Brain Ischemia; Carotid Stenosis; Drug Therapy, Combination; Fluorescein Angiography; Glucocorticoids; Humans; Immunosuppressive Agents; Laser Coagulation; Magnetic Resonance Imaging; Male; Methotrexate; Optic Neuropathy, Ischemic; Prednisone; Takayasu Arteritis	2012
[Use of NSAIDs in rheumatoid arthritis should be limited]. Ugeskrift for laeger, 2013, Apr-08, Volume: 175, Issue:15 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Drug Interactions; Drug Therapy, Combination; Humans; Methotrexate; Review Literature as Topic	2013
Aspirin antagonizes the cytotoxic effect of methotrexate in lung cancer cells. Oncology reports, 2013, Volume: 30, Issue:3 Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Apoptosis; Aspirin; Blotting, Western; Cell Cycle; Cell Proliferation; Drug Antagonism; Humans; Lung Neoplasms; Methotrexate; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured	2013
Chemometrics-assisted Spectrofluorimetric Determination of Two Co-administered Drugs of Major Interaction, Methotrexate and Aspirin, in Human Urine Following Acid-induced Hydrolysis. Combinatorial chemistry & high throughput screening, 2015, Volume: 18, Issue:8 Topics: Aspirin; Computational Biology; Drug Interactions; Drug Therapy, Combination; Humans; Hydrolysis; Methotrexate; Spectrometry, Fluorescence; Urinalysis	2015
Bilateral ocular ischemia-induced blindness as a presenting manifestation of Takayasu arteritis: a case report. Journal of medical case reports, 2017, Jun-10, Volume: 11, Issue:1 Topics: Anti-Inflammatory Agents; Aspirin; Blindness; Computed Tomography Angiography; Dexamethasone; Female; Humans; Methotrexate; Optic Neuropathy, Ischemic; Quality of Life; Takayasu Arteritis; Treatment Outcome; Weight Loss; Young Adult	2017
A non-interventional retrospective cohort study of the interaction between methotrexate and proton pump inhibitors or aspirin. Annales pharmaceutiques francaises, 2017, Volume: 75, Issue:5 Topics: Aspirin; Drug Interactions; Humans; Methotrexate; Proton Pump Inhibitors; Retrospective Studies	2017
Management of methotrexate and low-dose acetylsalicylic acid interaction in a child with acute lymphoblastic leukemia and moyamoya disease: A case report. Pediatric blood & cancer, 2023, Volume: 70, Issue:10 Topics: Aspirin; Child; Humans; Methotrexate; Moyamoya Disease; Precursor Cell Lymphoblastic Leukemia-Lymphoma	2023