aspirin and mercaptopurine

aspirin has been researched along with mercaptopurine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199010 (41.67)18.7374
1990's0 (0.00)18.2507
2000's7 (29.17)29.6817
2010's6 (25.00)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Kim, DN; Kwak, YS; Lee, KT1
Ackermann, R; Frohmüller, H; Kühner, U1
Steinberg, AD1
Fischer, J; Jahn, U; Wagner-Jauregg, T1
Arrigoni-Martelli, E; Schiatti, P; Selva, D1
Finkelstein, RA; Goth, A; Lexomboon, U1
Dietrich, FM; Hess, R1
Kadokawa, T; Nakamura, H; Nakamura, K; Nakatsuji, K1
Nagra, CL; Rosenthale, ME1
Graeme, ML; John, M; Sigg, EB1
Kruis, W; Schreiber, S1
Vogt, W1

Reviews

3 review(s) available for aspirin and mercaptopurine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
An approach to the use of immunosuppressive drugs in nonmalignant diseases.
    The Journal of allergy and clinical immunology, 1973, Volume: 52, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chlorambucil; Cyclophosphamide; Granulomatosis with Polyangiitis; Hepatitis; Humans; Immunosuppressive Agents; Liver Cirrhosis; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Mice; Mice, Inbred NZB; Multiple Sclerosis; Nephritis; Nephrosis; Nitrogen Mustard Compounds; Penicillins; Psoriasis; Uveitis, Anterior

1973
[Inflammatory bowel disease--diagnosis and therapy].
    Praxis, 2005, Feb-02, Volume: 94, Issue:5

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azathioprine; Colitis, Ulcerative; Controlled Clinical Trials as Topic; Crohn Disease; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Placebos; Practice Guidelines as Topic; Quality of Life; Remission Induction; Time Factors

2005

Other Studies

21 other study(ies) available for aspirin and mercaptopurine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Study of drugs affecting cholesterol-induced atherosclerosis in rabbits.
    Advances in experimental medicine and biology, 1976, Volume: 67, Issue:00

    Topics: Animals; Arteriosclerosis; Aspirin; Chloroquine; Cholesterol, Dietary; Clomipramine; Hydroxyurea; Male; Mercaptopurine; Pharmacology; Pyridinolcarbamate; Rabbits; Sodium Dodecyl Sulfate

1976
[Diagnosis and treatment of panarteritis in childhood].
    Klinische Padiatrie, 1972, Volume: 184, Issue:5

    Topics: Antihypertensive Agents; Aspirin; Biopsy; Child; Cyclic P-Oxides; Ethylamines; Female; Humans; Immunosuppressive Agents; Mercaptopurine; Oxazines; Penicillins; Platelet Adhesiveness; Polyarteritis Nodosa; Prednisone; Urography

1972
[Cytostatic antiphlogistics. II. Antimicrobial activity range and comparison in the Oedipus test].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Aspirin; Azaguanine; Azathioprine; Bacteria; Benzimidazoles; Depression, Chemical; Edema; Enterococcus faecalis; Flufenamic Acid; Fungi; Indomethacin; Lactobacillus; Mefenamic Acid; Mercaptopurine; Oxyphenbutazone; Phenylbutazone; Purines; Pyrimethamine; Rats; Riboflavin; Salicylates; Staphylococcus; Tetracycline; Thioguanine

1970
The influence of anti-inflammatory and immunosuppressant drugs on Nystatin induced oedema.
    Pharmacology, 1971, Volume: 5, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Arthritis; Aspirin; Azathioprine; Chloramphenicol; Cyclophosphamide; Dexamethasone; Drug Antagonism; Edema; Hydrocortisone; Immunosuppressive Agents; Indomethacin; Inflammation; Male; Mefenamic Acid; Mercaptopurine; Nystatin; Phenylacetates; Phenylbutazone; Prednisolone; Rats; Rifampin; Triamcinolone

1971
Applications of the mouse foot edema test in evaluation of anti-cholera drugs.
    Research communications in chemical pathology and pharmacology, 1971, Volume: 2, Issue:2

    Topics: Animals; Anti-Infective Agents; Aspirin; Chloramphenicol; Cholera; Cycloheximide; Dactinomycin; Diuretics; Edema; Emetine; Enterotoxins; Ethacrynic Acid; Fasting; Furosemide; Indomethacin; Iproniazid; Mercaptopurine; Mice; Models, Biological; Phenylbutazone; Protein Biosynthesis; Puromycin; Time Factors; Triamcinolone

1971
Hypersensitivity in mice. I. Induction of contact sensitivity to oxazolone and inhibition by various chemical compounds.
    International archives of allergy and applied immunology, 1970, Volume: 38, Issue:3

    Topics: Animals; Antigens; Aspirin; Cortisone; Corynebacterium; Cyclophosphamide; Dermatitis, Contact; Dexamethasone; Drug Hypersensitivity; Ear; Flumethasone; Glucocorticoids; Immunosuppressive Agents; Mercaptopurine; Mice; Oxazoles; Paramethasone; Phenylbutazone; Prednisone; Skin Tests

1970
Pharmacological studies of a new anti-inflammatory drug, 1-phenylsulfonyl-5,5-diphenylhydantoin (PC-796) in experimental animals. I. Anti-inflammatory, analgesic and anti-pyretic activity.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Aminopyrine; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Capillary Permeability; Carrageenan; Croton Oil; Depression, Chemical; Edema; Exudates and Transudates; Female; Guinea Pigs; Indomethacin; Inflammation; Male; Mefenamic Acid; Mercaptopurine; Mice; Phenylbutazone; Phenytoin; Pregnanes; Protein Denaturation; Rabbits; Radiation-Protective Agents; Rats; Sulfones; Yeast, Dried

1970
Comparative effects of some immunosuppressive and anti-inflammotory drugs on allergic encephalomyelitis and adjuvant arthritis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 125, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Blood Cell Count; Body Weight; Cortisone; Encephalomyelitis, Autoimmune, Experimental; Immunosuppressive Agents; Male; Mercaptopurine; Organ Size; Phenylbutazone; Rats

1967
Induction of periarthritis by oral administration of 6-sulfanilamidoindazole and its treatment in rats.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:1

    Topics: Animals; Aspirin; Chloroquine; Cloxacillin; Hydralazine; Hydrocortisone; Indomethacin; Male; Mercaptopurine; Methotrexate; Morphine; ortho-Aminobenzoates; Oxyphenbutazone; Paramethasone; Periarthritis; Phenylbutazone; Rats; Sulfinpyrazone; Sulfonamides

1967
[Ulcerative colitis. Maintenance therapy].
    Zeitschrift fur Gastroenterologie, 2004, Volume: 42, Issue:9

    Topics: Administration, Oral; Administration, Rectal; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azathioprine; Colitis, Ulcerative; Colorectal Neoplasms; Controlled Clinical Trials as Topic; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Mercaptopurine; Meta-Analysis as Topic; Patient Selection; Placebos; Proctitis; Remission Induction; Suppositories; Time Factors

2004