aspirin and lovastatin

aspirin has been researched along with lovastatin in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's5 (21.74)18.2507
2000's10 (43.48)29.6817
2010's7 (30.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Harada, T; Nakagawa, Y; Potter, PM; Wadkins, RM; Wheelock, CE1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Averna, M; Barbagallo, C; Catalano, I; Ciabattoni, G; Davì, G; Ganci, A; Notarbartolo, A; Patrono, C1
Paoletti, R; Sirtori, CR; Tremoli, E1
Buja, LM; Casscells, SW; Goff, DC; Gould, KL1
Aumont, MC; Seknadji, P1
Verheugt, FW1
Hensel, WA; McDiarmid, TD1
McCullough, PA1
Beckedorf, A; Bieberich, E; Silva, J1
Fang, CH; Li, JJ1
Xiao, H; Yang, CS1
Lan, XH; Li, X; Xu, R; Zhou, YG1

Reviews

4 review(s) available for aspirin and lovastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
New strategies in the development of anti-atherosclerotic drugs.
    Artery, 1980, Volume: 8, Issue:6

    Topics: 4-Aminobenzoic Acid; Animals; Arteriosclerosis; Aspirin; Coronary Disease; Fatty Acids, Nonesterified; Hepatomegaly; Humans; Hydrogen Peroxide; Hypolipoproteinemias; Lovastatin; Male; Metformin; Microbodies; Naphthalenes; Oligopeptides; para-Aminobenzoates; Platelet Aggregation; Rats

1980
[Secondary prevention after myocardial infarction; rôle of platelet antiaggregants and hypolipemic agents].
    Archives des maladies du coeur et des vaisseaux, 1996, Volume: 89 Spec No 3

    Topics: Anticholesteremic Agents; Aspirin; Coronary Disease; Cost-Benefit Analysis; Gemfibrozil; Humans; Hypolipidemic Agents; Lovastatin; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Simvastatin

1996
Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention.
    International journal of cancer, 2008, Sep-01, Volume: 123, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Atorvastatin; Celecoxib; Colorectal Neoplasms; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Evidence-Based Medicine; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Meta-Analysis as Topic; Neoplasms; Pravastatin; Pyrazoles; Pyridines; Pyrroles; Randomized Controlled Trials as Topic; Simvastatin; Sulfonamides; Sulindac

2008

Other Studies

19 other study(ies) available for aspirin and lovastatin

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis.
    Bioorganic & medicinal chemistry, 2009, Jan-01, Volume: 17, Issue:1

    Topics: Carboxylesterase; Carboxylic Ester Hydrolases; Enzyme Inhibitors; Humans; Ketones; Quantitative Structure-Activity Relationship

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increased thromboxane biosynthesis in type IIa hypercholesterolemia.
    Circulation, 1992, Volume: 85, Issue:5

    Topics: Adult; Aged; Anticholesteremic Agents; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Thromboxane A2

1992
Non-invasive management of coronary artery disease. Report of a meeting at the University of Texas Medical School at Houston.
    Lancet (London, England), 1995, Sep-16, Volume: 346, Issue:8977

    Topics: Aged; Anticholesteremic Agents; Aspirin; beta Carotene; Carotenoids; Cholesterol, Dietary; Coronary Disease; Diet, Fat-Restricted; Diltiazem; Drug Therapy, Combination; Enalapril; Humans; Lovastatin; Male; Simvastatin; Tomography, Emission-Computed; Vitamins

1995
Aspirin, the poor man's statin?
    Lancet (London, England), 1998, Jan-24, Volume: 351, Issue:9098

    Topics: Anticoagulants; Aspirin; Female; Humans; Lovastatin; Male; Myocardial Infarction; Platelet Aggregation Inhibitors; Pravastatin; Risk Factors; Warfarin

1998
Coronary events with lipid-lowering therapy: the AFCAPS/TexCAPS trial. Air Force/Texas Coronary Atherosclerosis Prevention Study.
    JAMA, 1999, Feb-03, Volume: 281, Issue:5

    Topics: Anticholesteremic Agents; Aspirin; Coronary Disease; Cost-Benefit Analysis; Hormone Replacement Therapy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Platelet Aggregation Inhibitors; Risk

1999
The antiinflammatory effects of statins.
    The New England journal of medicine, 2001, Oct-18, Volume: 345, Issue:16

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; C-Reactive Protein; Cholesterol, LDL; Confounding Factors, Epidemiologic; Coronary Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Risk Factors

2001
Osteoblast-derived oxysterol is a migration-inducing factor for human breast cancer cells.
    The Journal of biological chemistry, 2003, Jul-11, Volume: 278, Issue:28

    Topics: Arachidonic Acid; Aspirin; Breast Neoplasms; Cell Membrane; Cell Movement; Cholesterol; Chromatography, High Pressure Liquid; Coculture Techniques; Culture Media, Conditioned; Dinoprostone; Electrophoresis, Polyacrylamide Gel; HSP70 Heat-Shock Proteins; Humans; Insulin-Like Growth Factor I; Lipid Metabolism; Lovastatin; MAP Kinase Signaling System; Microscopy, Fluorescence; Neoplasm Metastasis; Osteoblasts; Phospholipids; Phosphorylation; Prostaglandins B; Protein Transport; Proto-Oncogene Proteins p21(ras); Reverse Transcriptase Polymerase Chain Reaction; Sepharose; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sphingolipids; Sterols; Trypsin; Tumor Cells, Cultured

2003
C-reactive protein is not only an inflammatory marker but also a direct cause of cardiovascular diseases.
    Medical hypotheses, 2004, Volume: 62, Issue:4

    Topics: Acute-Phase Reaction; Aspirin; Atorvastatin; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Clinical Trials as Topic; Coronary Artery Disease; Heptanoic Acids; Humans; Incidence; Inflammation; Interleukin-6; Lovastatin; Pravastatin; Predictive Value of Tests; Pyrroles; Risk Factors; Simvastatin

2004
[Effects of three different treatments on atherosclerosis and adipose in rats].
    Zhonghua yi xue za zhi, 2012, Jun-19, Volume: 92, Issue:23

    Topics: Adipose Tissue; Animals; Aspirin; Atherosclerosis; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Lovastatin; Male; Probucol; Rats; Rats, Sprague-Dawley

2012