aspirin has been researched along with lipoxin a4 in 116 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (15.52) | 18.2507 |
| 2000's | 64 (55.17) | 29.6817 |
| 2010's | 31 (26.72) | 24.3611 |
| 2020's | 3 (2.59) | 2.80 |
| Authors | Studies |
|---|---|
| Brezinski, DA; Nesto, RW; Serhan, CN | 1 |
| Bertram, S; Drazen, JM; Fischer, A; Israel, E; Levy, BD; Serhan, CN; Tai, HH | 1 |
| Serhan, CN | 2 |
| Brady, HR; Fiore, S; Maddox, JF; Petasis, NA; Serhan, CN; Takano, T | 1 |
| Clish, CB; Gronert, K; Petasis, N; Serhan, CN; Takano, T | 2 |
| Gewirtz, A; Gronert, K; Madara, JL; Serhan, CN | 1 |
| Drazen, JM; Levy, BD; Serhan, CN | 1 |
| Chiang, N; Clish, CB; Petasis, NA; Serhan, CN; Tai, HH; Takano, T | 1 |
| Maddox, JF; Serhan, CN; Takano, T | 1 |
| Fokin, VV; Gewirtz, AT; Madara, JL; Petasis, NA; Serhan, CN | 1 |
| Clark, JM; Fokin, VV; Levy, BD; Petasis, NA; Serhan, CN; Wakelam, MJ | 1 |
| Chiang, N; Clish, CB; Gronert, K; Serhan, CN; Takano, T | 1 |
| Hachicha, M; Petasis, NA; Pouliot, M; Serhan, CN | 1 |
| Clish, CB; Gronert, K; O'Brien, JA; Petasis, NA; Serhan, CN; Stahl, GL | 1 |
| Chiang, N; Clish, CB; Freeman, MW; Gronert, K; O'Brien, JA; Serhan, CN | 1 |
| Chiang, N; Clària, J; Gaya, J; Pueyo, G; Romano, M; Serhan, CN; Titos, E | 2 |
| Bandeira-Melo, C; Bozza, PT; Cordeiro, RS; Diaz, BL; Jose, PJ; Martins, MA; Serhan, CN | 2 |
| Pouliot, M; Serhan, CN | 1 |
| Chiang, N; Fierro, IM; Gronert, K; Serhan, CN | 1 |
| Clish, CB; Petasis, NA; Pouliot, M; Serhan, CN; Van Dyke, TE | 1 |
| Clish, CB; Gronert, K; Serhan, CN | 1 |
| Chiang, N; Clish, CB; Gronert, K; Levy, BD; Mastalerz, L; Sanak, M; Serhan, CN; Szczeklik, A | 1 |
| Chiang, N; Clish, CB; Gronert, K; Levy, BD; Serhan, CN | 1 |
| Clish, CB; Serhan, CN | 1 |
| Chiang, N; Gronert, K; Martinsson-Niskanen, T; Ravasi, S; Serhan, CN | 1 |
| Chiang, N; Fierro, IM; Pouliot, M; Serhan, CN | 1 |
| Qiu, FH; Serhan, CN; Stahl, GL; Wada, K | 1 |
| Fierro, IM; Serhan, CN | 1 |
| Baird, AW; Bernasconi, G; Brady, HR; Cottell, D; Godson, C; Goh, J; MacMathuna, P; O'Keane, C; Petasis, NA; Watson, RW | 1 |
| Devchand, PR; Qiu, FH; Serhan, CN; Wada, K | 1 |
| Filep, JG; József, L; Petasis, NA; Serhan, CN; Zouki, C | 1 |
| Arroyo, V; Clària, J; Gaya, J; López-Parra, M; Planagumà, A; Pueyo, G; Titos, E | 1 |
| de Lima, OM; Dicay, M; Distrutti, E; Fiorucci, S; Ma, L; McKnight, W; Mencarelli, A; Morelli, A; Palazzetti, B; Romano, M; Wallace, JL | 1 |
| Asadullah, K; Bauman, J; Colgan, SP; Fierro, IM; Giesen, C; Guilford, W; Parkinson, JF; Perez, HD; Schottelius, AJ | 1 |
| Serhan, CN; Van Dyke, TE | 1 |
| Arita, M; Bernasconi, G; Clish, CB; Colgan, SP; Fierro, IM; Petasis, NA; Serhan, CN | 1 |
| de Lima, OM; Fiorucci, S; Souza, MH; Wallace, JL; Zamuner, SR | 1 |
| Filep, JG; Hachicha, M; Petasis, NA; Serhan, CN; Zouki, C | 1 |
| Barbanti, M; de Lima, OM; Distrutti, E; Fiorucci, S; Mencarelli, A; Morelli, A; Palazzini, E; Romano, M; Wallace, JL | 1 |
| Ackerman, K; De Sanctis, GT; Devchand, PR; Drazen, JM; Kim, E; Levy, BD; Schmidt, B; Serhan, CN; Szczeklik, W | 1 |
| Ariel, A; Arita, M; Chiang, N; Petasis, NA; Serhan, CN | 1 |
| Fiorucci, S; Wallace, JL | 1 |
| Cirino, G; Distrutti, E; Fiorucci, S; Laufor, SA; Mencarelli, A; Morelli, A; Wallace, JL | 1 |
| Levy, B; Serhan, CN | 1 |
| Bienkiewicz, B; DuBuske, L; Kowalski, ML; Pawliczak, R; Ptasinska, A | 1 |
| del Soldato, P; Dicay, M; Fiorucci, S; McKnight, W; Mencarelli, A; Wallace, JL; Zamuner, SR | 1 |
| Cooper, D; Gilroy, DW; Moradi-Bidhendi, N; Paul-Clark, MJ; Van Cao, T | 1 |
| Bannenberg, G; Bauman, JG; Devchand, PR; Gronert, K; Guilford, WJ; Moussignac, RL; Parkinson, JF; Perez, HD; Schmidt, BA; Serhan, CN; Subramanyam, B | 1 |
| Fiorucci, S; Hollenberg, MD; von der Weid, PY; Wallace, JL | 1 |
| Bermudez, EA; Chiang, N; Hurwitz, S; Ridker, PM; Serhan, CN | 1 |
| Arruda, MA; Barja-Fidalgo, C; Fierro, IM; Nascimento-Silva, V; Villela, CG | 1 |
| Sakakibara, H; Yoneda, Y | 1 |
| Devchand, PR | 1 |
| Fierro, IM; Simões, RL | 1 |
| Schröder, H | 1 |
| Cezar-de-Mello, PF; Fierro, IM; Nascimento-Silva, V; Villela, CG | 1 |
| Chiang, N; Hurwitz, S; Ridker, PM; Serhan, CN | 1 |
| Aliberti, J; Bafica, A; Dias, A; Esper, L; Johndrow, JE; Machado, FS; Serhan, CN | 1 |
| Romano, M | 1 |
| Parkinson, JF | 1 |
| Wallace, JL | 1 |
| Schwab, JM; Serhan, CN | 1 |
| Calixto, JB; Henriques, Md; Kassuya, CA; Menezes-de-Lima, O; Nascimento, AF | 1 |
| Brink, C; Chiang, N; Dahlén, SE; Drazen, JM; Hay, DW; Rovati, GE; Serhan, CN; Shimizu, T; Yokomizo, T | 1 |
| Arruda, MA; Barja-Fidalgo, C; Fierro, IM; Nascimento-Silva, V | 1 |
| Jin, SW; Lian, QQ; Liu, D; Wu, P; Yao, SL; Ye, DY; Zhang, L | 1 |
| Serhan, CN; Svensson, CI; Zattoni, M | 1 |
| Birnbaum, Y; Freeberg, SY; Huang, MH; Lin, Y; Perez-Polo, JR; Uretsky, BF; Ye, Y | 1 |
| Chiang, N; Serhan, CN | 1 |
| El Kebir, D; Filep, JG; József, L; Khreiss, T; Pan, W; Petasis, NA; Serhan, CN | 1 |
| Badovinac, RL; Hosokawa, I; Howell, TH; Karimbux, NY; Kawai, T; Kim, DM; Koszeghy, KL | 1 |
| Celik, GE; Erkekol, FO; Melli, M; Misirligil, Z | 1 |
| Hopkinson, P; Lipworth, BJ; Meldrum, KT; Menzies, D; Nair, A | 1 |
| El Kebir, D; Filep, JG; József, L | 1 |
| Benjamim, CF; Canetti, C; e Silva, PM; Farias-Filho, FA; Ferreira, TP; Fierro, IM; Hogaboam, CM; Kunkel, SL; Martins, V; Molinaro, R; Simões, RL; Valença, SS | 1 |
| Antczak, A; Kuna, P; Kupczyk, M; Kuprys-Lipinska, I | 1 |
| El Kebir, D; Filep, JG; József, L; Pan, W; Petasis, NA; Serhan, CN; Wang, L | 1 |
| Bellingan, G; Colville-Nash, P; de Souza, P; Gilroy, DW; Hobbs, A; Morris, T; Newson, J; Stables, M; Warner, T | 1 |
| Menezes-de-Lima, O; Pamplona, FA; Takahashi, RN | 1 |
| Bellingan, G; Colville-Nash, P; de Souza, PM; Gilroy, DW; Morris, T; Newson, J; Stables, M | 1 |
| Conte, FP; Cunha, FQ; Henriques, MG; Menezes-de-Lima, O; Penido, C; Verri, WA | 1 |
| Basselin, M; Chen, M; Ramadan, E; Rapoport, SI | 1 |
| Serhan, CN; Spite, M | 1 |
| Flower, RJ; Norling, LV; Perretti, M; Serhan, CN; Spite, M; Yang, R | 1 |
| Li, LY; Liu, RG; Shang, Y; Wang, YP; Wu, Y; Yao, SL; Yuan, SY; Zheng, J; Zhou, JP | 1 |
| Bouchier-Hayes, D; Condron, C; Cunningham, AJ; Gang, C; Scully, M | 1 |
| Akiyama, K; Higashi, N; Komase, Y; Mita, H; Miyazawa, T; Nakagawa, T; Ono, E; Taniguchi, M; Yamaguchi, H | 1 |
| Li, L; Shang, Y; Sun, S; Wang, F; Wang, Y; Wu, J; Wu, Y; Yao, S; Zhai, H | 1 |
| Baglietto-Vargas, D; Cheng, D; Cribbs, DH; Kitazawa, M; LaFerla, FM; Medeiros, R; Passos, GF | 1 |
| Campos-Estrada, C; Castillo, C; Escanilla, S; Faúndez, M; Henriquez, N; Kemmerling, U; López-Muñoz, RA; Maya, JD; Molina-Berríos, A; Morello, A; Torres, G | 1 |
| Brancaleone, V; Cenac, N; Colom, B; Flower, RJ; Gobbetti, T; le Faouder, P; Nourshargh, S; Perretti, M; Vergnolle, N | 1 |
| Chan, MV; Edmands, WM; Holmes, E; Kirkby, NS; Lundberg, MH; MacKenzie, LS; Massey, KA; Mitchell, JA; Nicolaou, A; Warner, TD | 1 |
| Li, Q; Liu, SB; Ma, HJ; Mi, WL; Tian, Y; Wang, J; Wang, YQ; Wang, ZF; Wu, GC; Yu, J | 1 |
| Liu, R; Shang, Y; Wan, Z; Wang, Z; Wu, Y; Yang, D; Yao, C; Yao, S; Yuan, S | 1 |
| Auricchio, N; Blenis, J; Csibi, A; Gu, X; Guo, Y; Henske, EP; Israel, E; Kazani, S; Kwiatkowski, D; Lee, PS; Levy, BD; Li, C; Li, J; Morrison, T; Parkhitko, A; Planaguma, A; Priolo, C; Sun, Y; Wu, CL; Xu, KF; Yu, JJ; Zhang, E | 1 |
| Afonso, J; Albino-Teixeira, A; Bettencourt, P; Carvalho, F; Carvalho, J; Reina-Couto, M; Sousa, T; Vale, L; Valente, MJ | 1 |
| Cebrián, C; Esquivias, P; García-González, MA; Lanas, A; Morandeira, A; Ortego, J; Piazuelo, E; Santander, S | 1 |
| Hu, S; Jiang, JW; Li, Q; Liu, SB; Ma, HJ; Mao-Ying, QL; Mi, WL; Tian, Y; Wang, YQ; Wang, ZF; Wu, GC; Zhao, J | 1 |
| Birnbaum, Y; Kodakandla, M; Ling, S; Nanhwan, MK; Nylander, S; Ye, Y | 1 |
| Bins, A; Headley, M; Krummel, MF; Looney, MR; Mallavia, B; Ortiz-Muñoz, G | 1 |
| Andersson, R; Chen, B; Jin, Y; Sun, H; Wang, W; Xie, J; Xie, Y; Xu, D; Yang, F; Zhou, M | 1 |
| Zimring, JC | 1 |
| Bäck, M; Hedin, U; Laguna-Fernandez, A; Perretti, M; Petri, MH; Tseng, CN | 1 |
| Cianci, E; Recchiuti, A; Romano, M; Simiele, F | 1 |
| Carr, AJ; Dakin, SG; Dean, BJ; Martinez, FO; Oppermann, U; Roche, L; Smith, RD; Watkins, B; Wells, G; Wheway, K; Yapp, C | 1 |
| Arnardottir, H; Bäck, M; Hansson, GK; Laguna-Fernandez, A; Perretti, M; Petri, MH; Wheelock, CE | 1 |
| Bernis, C; de Sequera, P; Fernández-Juarez, G; García de Vinuesa, S; Goicoechea, M; Luño, J; Morales, E; Ortiz, A; Quiroga, B; Sanchez-Niño, MD; Verdalles, U; Verde, E | 1 |
| Alemanno, L; Canny, GO; Caserta, D; Frati, L; Frega, A; Guarino, ML; Mallozzi, M; Maltese, T; Marci, R; Massimi, I; Piscitelli, VP; Pulcinelli, FM | 1 |
| Bielenberg, DR; Gartung, A; Gilligan, MM; Huang, S; Kieran, MW; Norris, PC; Panigrahy, D; Serhan, CN; Sukhatme, VP; Sulciner, ML | 1 |
| Alvarez, AM; Cadavid J, AP; Gil-Villa, AM; Rojas-López, M; Velásquez-Berrío, M | 1 |
| Fulcher, I; Hennessy, A; Kumar, R; Lee, G; Makris, A; Motum, P; Shanmugalingam, R; Wang, X | 1 |
| AlaEddine, M; Authier, H; Bernad, J; Bouschbacher, M; Coste, A; Dardenne, C; Lefèvre, L; Meunier, E; Pipy, B; Salon, M | 1 |
21 review(s) available for aspirin and lipoxin a4
| Article | Year |
|---|---|
Lipoxins and novel aspirin-triggered 15-epi-lipoxins (ATL): a jungle of cell-cell interactions or a therapeutic opportunity?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acids; Aspirin; Cell Communication; Hydroxyeicosatetraenoic Acids; Leukotriene A4; Lipoxins; Models, Biological; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin | 1997 |
Aspirin-triggered 15-epi-lipoxin A4 and stable analogs on lipoxin A4 are potent inhibitors of acute inflammation. Receptors and pathways.
Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Base Sequence; Binding Sites; Disease Models, Animal; Ear; Humans; Hydroxyeicosatetraenoic Acids; Leukocytes; Lipoxins; Mice; Molecular Sequence Data; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Tissue Distribution | 1999 |
Lipoxin and aspirin-triggered 15-epi-lipoxin cellular interactions anti-inflammatory lipid mediators.
Topics: Amino Acid Sequence; Animals; Aspirin; Dermatitis; Disease Models, Animal; Endothelium; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Molecular Sequence Data; Monocytes; Neutrophils; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Sequence Homology, Amino Acid | 1999 |
Lipoxins, aspirin-triggered 15-epi-lipoxin stable analogs and their receptors in anti-inflammation: a window for therapeutic opportunity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Inflammation Mediators; Lipoxins; Models, Molecular; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Signal Transduction; Stereoisomerism | 2000 |
Mechanisms in anti-inflammation and resolution: the role of lipoxins and aspirin-triggered lipoxins.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Autacoids; Cytokines; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Inflammation Mediators; Lipids; Lipoxins; Lipoxygenase | 2001 |
Lipoxins and aspirin-triggered 15-epi-lipoxins are endogenous components of antiinflammation: emergence of the counterregulatory side.
Topics: Animals; Arachidonate 5-Lipoxygenase; Aspirin; Eicosanoids; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Lipoxins; Neutrophils; Receptors, Leukotriene B4; Signal Transduction | 2001 |
Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 15-Lipoxygenase; Aspirin; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Inflammation Mediators; Leukotrienes; Lipoxins; Neutrophil Activation; Neutrophils; Periodontitis; Prostaglandins | 2003 |
Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 modulate adhesion molecule expression on human leukocytes in whole blood and inhibit neutrophil-endothelial cell adhesion.
Topics: Antigens, CD; Aspirin; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Humans; Hydroxyeicosatetraenoic Acids; L-Selectin; Leukocytes; Lipoxins; Neutrophils | 2002 |
A magic bullet for mucosal protection...and aspirin is the trigger!
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Synergism; Gastric Mucosa; Humans; Hydroxyeicosatetraenoic Acids; Isoenzymes; Lipoxins; Membrane Proteins; Prostaglandin-Endoperoxide Synthases | 2003 |
Novel pathways and endogenous mediators in anti-inflammation and resolution.
Topics: Animals; Arachidonate 5-Lipoxygenase; Aspirin; Cell Communication; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Leukotriene A4; Lipoxins; Prostaglandins | 2003 |
[Aspirin-induced asthma (AIA)].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cyclooxygenase Inhibitors; Dinoprostone; Eosinophils; Humans; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipoxins; Mast Cells; Prostaglandin-Endoperoxide Synthases | 2005 |
New signaling routes for an old drug: lipoxin A4 might mediate heme oxygenase-1 induction by aspirin. Focus on "Novel lipid mediator aspirin-triggered lipoxin A4 induces heme oxygenase-1 in endothelial cells".
Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Endothelial Cells; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Lipoxins; Membrane Proteins; Signal Transduction | 2005 |
Lipid mediators: lipoxin and aspirin-triggered 15-epi-lipoxins.
Topics: Acetylation; Animals; Anti-Inflammatory Agents; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arthritis; Aspirin; Asthma; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Lipoxins; Periodontitis | 2006 |
Lipoxin and synthetic lipoxin analogs: an overview of anti-inflammatory functions and new concepts in immunomodulation.
Topics: Acetylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Humans; Hypersensitivity; Immunity, Cellular; Immunologic Factors; Lipoxins; Mice; Mice, Transgenic; Receptors, Formyl Peptide; Receptors, Lipoxin; T-Lymphocytes | 2006 |
Nitric oxide, aspirin-triggered lipoxins and NO-aspirin in gastric protection.
Topics: Acetylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Lipoxins; Nitrates; Nitric Oxide; Nitric Oxide Donors | 2006 |
Lipoxins and new lipid mediators in the resolution of inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Disease Models, Animal; Docosahexaenoic Acids; Eicosapentaenoic Acid; Humans; Inflammation; Lipid Metabolism; Lipoxins; Signal Transduction | 2006 |
The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo.
Topics: Animals; Aspirin; Cysteine; Humans; Leukotrienes; Ligands; Lipids; Lipoxins; Models, Biological; Molecular Conformation; Molecular Sequence Data; Peptides; Phylogeny; Receptors, Aryl Hydrocarbon; Receptors, Formyl Peptide; Receptors, G-Protein-Coupled; Receptors, Growth Factor; Receptors, Lipoxin; Signal Transduction; Substrate Specificity | 2006 |
New mechanism for an old drug: aspirin triggers anti-inflammatory lipid mediators with gender implications.
Topics: Acetylation; Aspirin; Cyclooxygenase Inhibitors; Humans; Lipoxins; Neutrophils; Randomized Controlled Trials as Topic; Sex Factors; Thromboxane B2 | 2006 |
Opposing regulation of neutrophil apoptosis through the formyl peptide receptor-like 1/lipoxin A4 receptor: implications for resolution of inflammation.
Topics: Annexin A1; Apoptosis; Apoptosis Regulatory Proteins; Aspirin; Humans; Lipoxins; Neutrophil Activation; Neutrophil Infiltration; Neutrophils; Receptors, Formyl Peptide; Receptors, Lipoxin; Serum Amyloid A Protein | 2008 |
Novel lipid mediators promote resolution of acute inflammation: impact of aspirin and statins.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Aspirin; Cardiovascular Diseases; Cyclooxygenase 2; Fatty Acids, Omega-3; Homeostasis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Inflammation Mediators; Lipid Metabolism; Lipoxins | 2010 |
Lipoxins and aspirin-triggered lipoxins in resolution of inflammation.
Topics: Animals; Aspirin; Humans; Inflammation; Inflammation Mediators; Lipoxins; Signal Transduction | 2015 |
9 trial(s) available for aspirin and lipoxin a4
| Article | Year |
|---|---|
Agonist-induced lipoxin A4 generation: detection by a novel lipoxin A4-ELISA.
Topics: Adult; Aspirin; Asthma; Body Fluids; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Reproducibility of Results; Sensitivity and Specificity | 1993 |
Agonist-induced lipoxin A4 generation in vitro and in aspirin-sensitive asthmatics: detection by a novel lipoxin A4-ELISA.
Topics: Aspirin; Asthma; Blood Platelets; Cross-Over Studies; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Neutrophils; Random Allocation; Recombinant Proteins | 1997 |
Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Female; Humans; Inflammation Mediators; Isoenzymes; Lipoxins; Male; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; Thromboxane B2 | 2004 |
Aspirin has a gender-dependent impact on antiinflammatory 15-epi-lipoxin A4 formation: a randomized human trial.
Topics: Acetylation; Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Humans; Lipoxins; Middle Aged; Placebos; Sex Characteristics; Thromboxane B2 | 2006 |
The effect of aspirin on gingival crevicular fluid levels of inflammatory and anti-inflammatory mediators in patients with gingivitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dental Plaque Index; Dinoprostone; Female; Gingival Crevicular Fluid; Gingival Hemorrhage; Gingivitis; Humans; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Leukotriene B4; Lipoxins; Male; Periodontal Pocket; Placebos | 2007 |
Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Breath Tests; Bronchial Provocation Tests; Double-Blind Method; Female; Humans; Inflammation; Lipoxins; Lung; Male; Nitric Oxide; Placebos; Respiratory Function Tests; Thromboxane B2 | 2008 |
Effects of low-dose aspirin on acute inflammatory responses in humans.
Topics: Acute Disease; Aspirin; Blister; Cantharidin; Cell Adhesion; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Humans; Inflammation; Lipoxins; Macrophages; Male; Nitric Oxide; Receptors, Formyl Peptide; Receptors, Lipoxin; Up-Regulation | 2009 |
Dichotomy in duration and severity of acute inflammatory responses in humans arising from differentially expressed proresolution pathways.
Topics: Adult; Aspirin; Humans; Inflammation; Lipoxins; Male; Middle Aged; Receptors, Formyl Peptide; Receptors, Lipoxin; Time Factors | 2010 |
Low dose aspirin increases 15-epi-lipoxin A4 levels in diabetic chronic kidney disease patients.
Topics: Aged; Anti-Inflammatory Agents; Aspirin; Female; Glomerular Filtration Rate; Humans; Lipoxins; Male; Middle Aged; Renal Insufficiency, Chronic | 2017 |
86 other study(ies) available for aspirin and lipoxin a4
| Article | Year |
|---|---|
Angioplasty triggers intracoronary leukotrienes and lipoxin A4. Impact of aspirin therapy.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Aspirin; Coronary Disease; Coronary Vessels; Eicosanoids; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipoxins; Middle Aged | 1992 |
Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors.
Topics: Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Base Sequence; Chemotaxis, Leukocyte; CHO Cells; Cloning, Molecular; Cricetinae; Female; Guanosine Triphosphate; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Lipoxins; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neutrophils; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Tissue Distribution | 1997 |
Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Aspirin; Capillary Permeability; Hydroxyeicosatetraenoic Acids; Lipoxins; Mice; Mice, Inbred BALB C; Mice, Knockout; Molecular Structure; Neutrophils; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Leukotriene B4; Receptors, Lipoxin | 1998 |
Identification of a human enterocyte lipoxin A4 receptor that is regulated by interleukin (IL)-13 and interferon gamma and inhibits tumor necrosis factor alpha-induced IL-8 release.
Topics: Aspirin; Caco-2 Cells; Cloning, Molecular; Cyclooxygenase 2; Epithelial Cells; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Interferon-gamma; Interleukin-13; Interleukin-8; Intestinal Mucosa; Isoenzymes; Lipoxins; Membrane Proteins; Models, Immunological; Molecular Sequence Data; Prostaglandin-Endoperoxide Synthases; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: development of a specific 15-epi-LXA4 ELISA.
Topics: Animals; Aspirin; Cell Line; Chromatography, Liquid; Enzyme-Linked Immunosorbent Assay; Exudates and Transudates; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Mass Spectrometry; Mice; Neutrophil Activation; Neutrophils; Peritonitis; Sensitivity and Specificity | 1998 |
LXA4, aspirin-triggered 15-epi-LXA4, and their analogs selectively downregulate PMN azurophilic degranulation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Degranulation; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kinetics; Leukocyte Elastase; Lipoxins; Neutrophils; Receptors, IgG; Superoxides | 1999 |
Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a 'stop' signaling switch for aspirin-triggered lipoxin A4.
Topics: Aspirin; Brassica; Enzyme Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kinetics; Leukotriene B4; Lipoxins; Neutrophils; Phospholipase D; Polyisoprenyl Phosphates; Recombinant Proteins; Signal Transduction; Stereoisomerism; Superoxides | 1999 |
Lipoxin (LX)A4 and aspirin-triggered 15-epi-LXA4 inhibit tumor necrosis factor 1alpha-initiated neutrophil responses and trafficking: regulators of a cytokine-chemokine axis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemokine CXCL2; Chemokines; Cytokines; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Interleukin-1; Interleukin-4; Leukocytes; Lipoxins; Male; Mice; Molecular Structure; Monokines; Neutrophils; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Recombinant Proteins; RNA, Messenger; Superoxides; Tumor Necrosis Factor-alpha | 1999 |
Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo.
Topics: Animals; Aspirin; Chemotaxis, Leukocyte; Ear; Hydroxyeicosatetraenoic Acids; Lipoxins; Male; Mice; Mice, Inbred BALB C; Neutrophils; Recombinant Proteins; Skin; Skin Physiological Phenomena; Stereoisomerism; Tumor Necrosis Factor-alpha | 1999 |
Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion.
Topics: Animals; Arachidonate 5-Lipoxygenase; Aspirin; Cell Line; Cell Movement; Crosses, Genetic; Ear, External; Exudates and Transudates; Female; Hindlimb; HL-60 Cells; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Male; Mice; Mice, Transgenic; Neutrophils; Peritonitis; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Leukotriene B4; Receptors, Lipoxin; Reperfusion Injury; RNA, Messenger | 1999 |
Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4).
Topics: Animals; Aspirin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Isoenzymes; Lipoxins; Liver; Male; Membrane Proteins; Phenobarbital; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Thromboxane B2 | 1999 |
Aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogs inhibit neutrophil-mediated changes in vascular permeability.
Topics: Animals; Aspirin; Capillary Permeability; Cell Movement; Fatty Alcohols; Glycols; Hydroxyeicosatetraenoic Acids; Lipoxins; Mice; Mice, Inbred BALB C; Neutrophils; Receptors, Leukotriene B4 | 1999 |
Cutting edge: lipoxin (LX) A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking.
Topics: Allergens; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Migration Inhibition; Cell Movement; Dose-Response Relationship, Immunologic; Eosinophilia; Eosinophils; Female; Hydroxyeicosatetraenoic Acids; Lipoxins; Male; Ovalbumin; Pleurisy; Rats; Rats, Wistar | 2000 |
Lipoxin A4 and aspirin-triggered 15-epi-LXA4 inhibit tumor necrosis factor-alpha-initiated neutrophil responses and trafficking: novel regulators of a cytokine-chemokine axis relevant to periodontal diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemokine CXCL2; Chemokines; Chemotactic Factors; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-1; Interleukin-4; Lipoxins; Male; Mice; Mice, Inbred BALB C; Monokines; Neutrophil Infiltration; Neutrophils; Periodontal Diseases; Stereoisomerism; Tumor Necrosis Factor-alpha | 1999 |
Activation of lipoxin A(4) receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium; Cell Line; Chemokine CCL4; Chemokine CXCL2; CHO Cells; Cricetinae; Humans; Hydroxyeicosatetraenoic Acids; Ligands; Lipoxins; Macrophage Inflammatory Proteins; Major Histocompatibility Complex; Molecular Structure; Monokines; Neutrophils; Oligopeptides; Peptides; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Leukotriene B4; Receptors, Lipoxin; Serum Amyloid A Protein; Signal Transduction | 2000 |
Lipoxin A(4) analogues inhibit leukocyte recruitment to Porphyromonas gingivalis: a role for cyclooxygenase-2 and lipoxins in periodontal disease.
Topics: Aggressive Periodontitis; Animals; Aspirin; Bacteroidaceae Infections; Bronchoalveolar Lavage Fluid; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Gingival Crevicular Fluid; Humans; Hydroxyeicosatetraenoic Acids; Isoenzymes; Leukotriene B4; Lipoxins; Lung; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Myocardium; Neutrophil Infiltration; Neutrophils; Porphyromonas gingivalis; Prostaglandin-Endoperoxide Synthases; RNA, Messenger | 2000 |
Local and systemic delivery of an aspirin-triggered lipoxin stable analog inhibits neutrophil trafficking.
Topics: Animals; Aspirin; Cell Movement; Drug Carriers; Hydroxyeicosatetraenoic Acids; Inflammation; Lipoxins; Mice; Neutrophils; Tumor Necrosis Factor-alpha | 2000 |
Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics.
Topics: Adult; Aspirin; Asthma; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene C4; Lipoxins; Male; Middle Aged; Stereoisomerism | 2000 |
Aspirin triggered lipid mediators: novel inhibitors of leucocyte trafficking.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Movement; Cyclooxygenase Inhibitors; Cytokines; Exudates and Transudates; Hydroxyeicosatetraenoic Acids; Lipid Metabolism; Lipoxins; Male; Mice; Mice, Inbred BALB C; Neutrophils; Tumor Necrosis Factor-alpha | 2000 |
Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses.
Topics: Animals; Aspirin; Binding, Competitive; Capillary Permeability; Cell Line; COS Cells; Dose-Response Relationship, Drug; Gene Expression; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Leukotriene D4; Lipoxins; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Neutrophils; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Leukotriene; Receptors, Leukotriene B4; Receptors, Lipoxin; Recombinant Proteins; RNA; Stereoisomerism; Tritium | 2001 |
Cutting edge: nociceptin stimulates neutrophil chemotaxis and recruitment: inhibition by aspirin-triggered-15-epi-lipoxin A4.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium Signaling; Cell Movement; Chemotactic Factors; Chemotaxis, Leukocyte; Humans; Hydroxyeicosatetraenoic Acids; Injections, Intradermal; Intracellular Fluid; Lipoxins; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neutrophil Infiltration; Neutrophils; Nociceptin; Nociceptin Receptor; Opioid Peptides; Receptors, Opioid; RNA, Messenger | 2001 |
Inosine monophosphate and aspirin-triggered 15-epi-lipoxin A4 act in concert to regulate neutrophil trafficking: additive actions of two new endogenous anti-inflammatory mediators.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Drug Interactions; Humans; Hydroxyeicosatetraenoic Acids; Inosine Monophosphate; Lipoxins; Male; Mice; Mice, Inbred BALB C; Neutrophil Infiltration | 2001 |
Lipoxin A(4) and aspirin-triggered 15-epi-lipoxin A(4) antagonize TNF-alpha-stimulated neutrophil-enterocyte interactions in vitro and attenuate TNF-alpha-induced chemokine release and colonocyte apoptosis in human intestinal mucosa ex vivo.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Line; Chemokine CCL2; Chemokine CCL5; Chemokines; Enterocytes; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Interleukin-8; Intestinal Mucosa; Lipoxins; Microscopy, Electron; Neutrophils; Tumor Necrosis Factor-alpha | 2001 |
Aspirin-triggered lipoxin A4 and lipoxin A4 up-regulate transcriptional corepressor NAB1 in human neutrophils.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; DNA, Complementary; Gene Expression Regulation; GTP-Binding Proteins; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Models, Biological; Neutrophils; Receptors, Cell Surface; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transcription, Genetic; Up-Regulation | 2001 |
Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF-kappa B and AP-1 activation, and IL-8 gene expression in human leukocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Cell Nucleus; Cell Survival; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; Interleukin-8; Leukocytes; Lipoxins; Lymphocytes; Neutrophils; NF-kappa B; Peroxynitrous Acid; Ribonucleases; Superoxides; Transcription Factor AP-1 | 2002 |
Aspirin (ASA) regulates 5-lipoxygenase activity and peroxisome proliferator-activated receptor alpha-mediated CINC-1 release in rat liver cells: novel actions of lipoxin A4 (LXA4) and ASA-triggered 15-epi-LXA4.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Aspirin; Chemokine CXCL1; Chemokines; Chemokines, CXC; Chemotactic Factors; Dinoprostone; Hepatocytes; Hydroxyeicosatetraenoic Acids; Intercellular Signaling Peptides and Proteins; Kupffer Cells; Leukotriene B4; Lipoxins; Liver; Models, Biological; Rats; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2002 |
Cyclooxygenase-2-derived lipoxin A4 increases gastric resistance to aspirin-induced damage.
Topics: Animals; Aspirin; Celecoxib; Cell Adhesion; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Resistance; Gastric Mucosa; Hydroxyeicosatetraenoic Acids; Isoenzymes; Lactones; Leukocytes; Lipoxins; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Stomach; Sulfonamides; Sulfones | 2002 |
An aspirin-triggered lipoxin A4 stable analog displays a unique topical anti-inflammatory profile.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcimycin; Cell Movement; Chemotaxis, Leukocyte; Croton Oil; Disease Models, Animal; Diterpenes; Female; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Hypersensitivity, Delayed; Iloprost; Inflammation; Leukotriene B4; Lipoxins; Mice; Phthalic Anhydrides; Skin; Terpenes | 2002 |
Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit human neutrophil migration: comparisons between synthetic 15 epimers in chemotaxis and transmigration with microvessel endothelial cells and epithelial cells.
Topics: Aspirin; Carboxylic Acids; Cell Line; Cell Migration Inhibition; Cell Movement; Chemotaxis, Leukocyte; Endothelium, Vascular; Epithelial Cells; Esters; Humans; Hydroxyeicosatetraenoic Acids; Lipoxins; Microcirculation; Neutrophil Infiltration; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Recombinant Proteins; Stereoisomerism | 2003 |
Gastritis increases resistance to aspirin-induced mucosal injury via COX-2-mediated lipoxin synthesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Adhesion; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Susceptibility; Gastric Mucosa; Gastritis; Hydroxyeicosatetraenoic Acids; Isoenzymes; Lactones; Leukocytes; Lipoxins; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach Ulcer; Sulfones | 2003 |
Aspirin-triggered 15-epi-lipoxin A4 biosynthesis in rat liver cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Aspirin; Calcimycin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; DNA Primers; Hepatocytes; Hydroxyeicosatetraenoic Acids; Isoenzymes; Kinetics; Lipoxins; Liver; Membrane Proteins; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Transcription, Genetic | 2002 |
Inhibition of allergen-induced eosinophil migration by lipoxin (LX)A4 and aspirin-triggered 15-epi-LXA4.
Topics: Allergens; Animals; Aspirin; Chemotaxis, Leukocyte; Eosinophils; Hydroxyeicosatetraenoic Acids; Lipoxins; Rats; Rats, Wistar | 2002 |
Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin.
Topics: Acetates; Acetylation; Adaptation, Physiological; Animals; Arachidonate 5-Lipoxygenase; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gastric Mucosa; Hydroxyeicosatetraenoic Acids; Isoenzymes; Leukotriene B4; Lipoxins; Lipoxygenase Inhibitors; Models, Biological; Prostaglandin-Endoperoxide Synthases; Pyrroles; Rats | 2003 |
Lipoxins and aspirin-triggered lipoxins in airway responses.
Topics: Animals; Aspirin; Bronchi; Bronchial Hyperreactivity; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Leukocytes; Lipoxins; Male; Mice; Mice, Inbred BALB C; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin | 2003 |
Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signal-regulated kinase-dependent TNF-alpha secretion from human T cells.
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butadienes; CD3 Complex; Cell Separation; Enzyme Activation; Humans; Hydroxyeicosatetraenoic Acids; Immune Sera; Immunosuppressive Agents; Jurkat Cells; Leukocytes, Mononuclear; Lipoxins; Lymphocyte Activation; Mitogen-Activated Protein Kinases; Nitriles; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; T-Lymphocytes; Transfection; Tumor Necrosis Factor-alpha | 2003 |
Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin.
Topics: Acetates; Acetylation; Adhesiveness; Arachidonate 5-Lipoxygenase; Aspirin; CD11a Antigen; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; E-Selectin; Eicosanoids; Endothelial Cells; Endothelium, Vascular; Fatty Alcohols; Glycols; Humans; Isoenzymes; Leukocytes; Leukotriene B4; Lipopolysaccharides; Lipoxins; Lipoxygenase; Membrane Proteins; Neutrophils; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Pyrans; Pyrroles; Quinolines; Quinolones; Umbilical Cord; Up-Regulation | 2003 |
Differential effects of aspirin and misoprostol on 15-hydroxyeicosatetraenoic acid generation by leukocytes from aspirin-sensitive asthmatic patients.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Dinoprostone; Drug Tolerance; Eicosanoids; Female; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Ionophores; Leukocytes; Leukotriene C4; Lipoxins; Male; Middle Aged; Misoprostol | 2003 |
Aspirin, but not NO-releasing aspirin (NCX-4016), interacts with selective COX-2 inhibitors to aggravate gastric damage and inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Gastric Mucosa; Gastritis; Isoenzymes; Lipoxins; Male; Neutropenia; Neutrophil Infiltration; Nitric Oxide; Peroxidase; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Endothelium; Inflammation; Interleukin-1; Leukocytes; Lipoxins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Peritonitis; Rats; Rats, Wistar | 2004 |
Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration.
Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ear, External; Inflammation; Injections, Intravenous; Lipoxins; Lung Diseases; Male; Mice; Peritonitis; Reperfusion Injury; Zymosan | 2004 |
Aspirin-triggered, cyclooxygenase-2-dependent lipoxin synthesis modulates vascular tone.
Topics: Acetylcholine; Animals; Aorta; Aspirin; Blood Pressure; Celecoxib; Cyclooxygenase 2 Inhibitors; Endothelium, Vascular; Hydroxyurea; Lipoxins; Lipoxygenase Inhibitors; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Oligopeptides; Pyrazoles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Lipoxin; Sulfonamides; Vascular Resistance; Vasodilation; Vasodilator Agents | 2004 |
Novel lipid mediator aspirin-triggered lipoxin A4 induces heme oxygenase-1 in endothelial cells.
Topics: Acute-Phase Reaction; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; E-Selectin; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Lipoxins; Membrane Proteins; Oligopeptides; Pertussis Toxin; RNA, Messenger; Signal Transduction; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 2005 |
Lipoxin agonists: turn right! to path of resolving neutrophil.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Homeostasis; Humans; Inflammation Mediators; Lipoxins; Mice; Neutrophils; Signal Transduction; Time Factors | 2005 |
Involvement of the Rho-kinase/myosin light chain kinase pathway on human monocyte chemotaxis induced by ATL-1, an aspirin-triggered lipoxin A4 synthetic analog.
Topics: Actins; Aspirin; Chemotaxis, Leukocyte; Enzyme Activation; Humans; Inflammation Mediators; Intracellular Signaling Peptides and Proteins; Lipoxins; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Monocytes; Myosin-Light-Chain Kinase; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Formyl Peptide; Receptors, Lipoxin; rho-Associated Kinases | 2005 |
Aspirin-triggered Lipoxin A4 inhibition of VEGF-induced endothelial cell migration involves actin polymerization and focal adhesion assembly.
Topics: Actins; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Adhesion; Cell Movement; Cells, Cultured; Cytoskeleton; Endothelium, Vascular; Humans; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Lipoxins; Mitogen-Activated Protein Kinase 11; Neovascularization, Pathologic; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Time Factors; Vascular Endothelial Growth Factor A | 2006 |
Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basic Helix-Loop-Helix Transcription Factors; Brain; Cells, Cultured; Dendritic Cells; Inflammation; Interleukin-12; Lipoxins; Mice; Mice, Inbred C57BL; Receptors, Aryl Hydrocarbon; RNA, Messenger; Spleen; Suppressor of Cytokine Signaling Proteins; Toxoplasma | 2006 |
Lipoxin A4 inhibits acute edema in mice: implications for the anti-edematogenic mechanism induced by aspirin.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bradykinin; Carrageenan; Dinoprostone; Dose-Response Relationship, Drug; Edema; Foot; Hindlimb; Histamine; Indomethacin; Injections, Intraperitoneal; Leukocytes; Lipoxins; Male; Mice; Neutrophil Infiltration; Oligopeptides; Platelet Activating Factor; Pleurisy; Receptors, Lipoxin | 2006 |
Aspirin-triggered lipoxin A4 blocks reactive oxygen species generation in endothelial cells: a novel antioxidative mechanism.
Topics: Antioxidants; Aspirin; Cardiovascular Diseases; Cells, Cultured; Endothelium, Vascular; Humans; Lipoxins; NADPH Oxidases; NF-kappa B; Reactive Oxygen Species | 2007 |
Posttreatment with aspirin-triggered lipoxin A4 analog attenuates lipopolysaccharide-induced acute lung injury in mice: the role of heme oxygenase-1.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Heme Oxygenase-1; Lipopolysaccharides; Lipoxins; Lung Diseases; Male; Mice; Mice, Inbred C57BL; Random Allocation; Time Factors | 2007 |
Lipoxins and aspirin-triggered lipoxin inhibit inflammatory pain processing.
Topics: Animals; Aspirin; Astrocytes; Blotting, Western; Carrageenan; Hyperalgesia; Immunohistochemistry; Inflammation; Inflammation Mediators; Lipoxins; Male; Pain; Rats; Rats, Sprague-Dawley; Receptors, Lipoxin; Spinal Cord | 2007 |
Aspirin augments 15-epi-lipoxin A4 production by lipopolysaccharide, but blocks the pioglitazone and atorvastatin induction of 15-epi-lipoxin A4 in the rat heart.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atorvastatin; Biotin; Cyclooxygenase 2; Enzyme Induction; Heart; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Lipopolysaccharides; Lipoxins; Male; Myocardium; Nitroso Compounds; Pioglitazone; Pyrroles; Rats; Rats, Sprague-Dawley; Thiazolidinediones | 2007 |
Aspirin-triggered lipoxins override the apoptosis-delaying action of serum amyloid A in human neutrophils: a novel mechanism for resolution of inflammation.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Aspirin; Cell Survival; Cells, Cultured; Humans; Inflammation Mediators; Lipoxins; Membrane Potential, Mitochondrial; Neutrophils; Receptors, Lipoxin; Serum Amyloid A Protein; Time Factors | 2007 |
Lipoxin A4 levels in asthma: relation with disease severity and aspirin sensitivity.
Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Humans; Lipoxins; Male; Middle Aged; Severity of Illness Index | 2007 |
ATLa, an aspirin-triggered lipoxin A4 synthetic analog, prevents the inflammatory and fibrotic effects of bleomycin-induced pulmonary fibrosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Aspirin; Bleomycin; Immunity, Innate; Lipoxins; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Respiratory Function Tests; Survival Analysis | 2009 |
Lipoxin A4 generation is decreased in aspirin-sensitive patients in lysine-aspirin nasal challenge in vivo model.
Topics: Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Drug Tolerance; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Leukotriene C4; Lipoxins; Lysine; Middle Aged; Nasal Provocation Tests; Poaceae | 2009 |
15-epi-lipoxin A4 inhibits myeloperoxidase signaling and enhances resolution of acute lung injury.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Bronchoalveolar Lavage Fluid; Caspase 3; CD18 Antigens; Female; Humans; Interleukin-6; Leukocyte Count; Lipoxins; Lung; Mice; Mice, Inbred BALB C; Neutrophils; Peroxidase; Signal Transduction | 2009 |
Aspirin-triggered lipoxin induces CB1-dependent catalepsy in mice.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acids; Aspirin; Catalepsy; Central Nervous System Agents; Cyclooxygenase Inhibitors; Endocannabinoids; Lipoxins; Male; Mice; Models, Neurological; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Lipoxin; Rimonabant | 2010 |
Lipoxin A(4) attenuates zymosan-induced arthritis by modulating endothelin-1 and its effects.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Edema; Endothelin-1; Gene Expression Regulation; Heptanoic Acids; Knee Joint; Lipoxins; Male; Mice; Mice, Inbred C57BL; Neutrophils; RNA, Messenger; Zymosan | 2010 |
Anti-inflammatory effects of chronic aspirin on brain arachidonic acid metabolites.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Brain; Dinoprostone; Humans; Leukotriene B4; Lipopolysaccharides; Lipoxins; Male; Rats; Rats, Inbred F344; Thromboxane B2 | 2011 |
Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cell Movement; Chromatography, Liquid; Docosahexaenoic Acids; Humans; Inflammation; Keratinocytes; Lipids; Lipoxins; Male; Mice; Microspheres; Molecular Mimicry; Nanoparticles; Neutrophils; Peritonitis; Tandem Mass Spectrometry; Temporomandibular Joint; Temporomandibular Joint Disorders; Wound Healing | 2011 |
Aspirin-triggered lipoxin A4 attenuates LPS-induced pro-inflammatory responses by inhibiting activation of NF-κB and MAPKs in BV-2 microglial cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Enzyme Activation; Inflammation; Interleukin-1beta; Lipopolysaccharides; Lipoxins; Mice; Microglia; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2011 |
Protective role of cyclooxygenase (COX)-2 in experimental lung injury: evidence of a lipoxin A4-mediated effect.
Topics: Animals; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Iloprost; Lipoxins; Lung; Lung Injury; Male; Protective Agents; Pyrazoles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sulfonamides | 2012 |
Urinary concentrations of 15-epimer of lipoxin A(4) are lower in patients with aspirin-intolerant compared with aspirin-tolerant asthma.
Topics: Adult; Aged; Aspirin; Asthma, Aspirin-Induced; Female; Humans; Leukotriene E4; Lipoxins; Male; Middle Aged; ROC Curve | 2011 |
Aspirin-triggered lipoxin A₄ attenuates lipopolysaccharide-induced intracellular ROS in BV2 microglia cells by inhibiting the function of NADPH oxidase.
Topics: Aspirin; Cell Line; Lipopolysaccharides; Lipoxins; Microglia; NADPH Oxidases; Reactive Oxygen Species | 2012 |
Aspirin-triggered lipoxin A4 stimulates alternative activation of microglia and reduces Alzheimer disease-like pathology in mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Aspirin; Astrocytes; Brain; Cognition; Lipoxins; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; NF-kappa B; Phenotype; Protein Processing, Post-Translational; Synapses | 2013 |
Protective role of acetylsalicylic acid in experimental Trypanosoma cruzi infection: evidence of a 15-epi-lipoxin A₄-mediated effect.
Topics: Animals; Aspirin; Cell Line; Chagas Disease; Disease Models, Animal; Lipoxins; Male; Mice; Mice, Inbred BALB C; Trypanosoma cruzi | 2013 |
A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Vessels; Cytoprotection; Lipoxins; Male; Mice; Mice, Knockout; Microcirculation; Models, Biological; Prodrugs; Receptors, Formyl Peptide; Reperfusion Injury; Signal Transduction | 2013 |
Aspirin-triggered 15-epi-lipoxin A4 predicts cyclooxygenase-2 in the lungs of LPS-treated mice but not in the circulation: implications for a clinical test.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Gene Expression Regulation; Lipopolysaccharides; Lipoxins; Lung; Mice | 2013 |
Involvement of the spinal NALP1 inflammasome in neuropathic pain and aspirin-triggered-15-epi-lipoxin A4 induced analgesia.
Topics: Analgesia; Animals; Aspirin; Chronic Disease; Drug Therapy, Combination; Inflammasomes; Injections, Spinal; Lipoxins; Male; Nerve Tissue Proteins; Neuralgia; Rats; Rats, Sprague-Dawley; Spinal Cord | 2013 |
Aspirin-triggered lipoxin A4 attenuates lipopolysaccharide induced inflammatory response in primary astrocytes.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Aspirin; Astrocytes; Cells, Cultured; Cyclooxygenase 2; Inflammation; Lipopolysaccharides; Lipoxins; Neuroimmunomodulation; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Signal Transduction | 2014 |
Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells.
Topics: Analysis of Variance; Animals; Aspirin; Breath Tests; Carcinogenesis; Carrier Proteins; Cell Proliferation; Cyclooxygenase 2; Estradiol; Female; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; Humans; Immunoblotting; Immunohistochemistry; Lipoxins; Lymphangioleiomyomatosis; Mechanistic Target of Rapamycin Complex 2; Metabolomics; Mice; Mice, SCID; Microscopy, Confocal; Multiprotein Complexes; Naphthyridines; Prostaglandins; Rapamycin-Insensitive Companion of mTOR Protein; Real-Time Polymerase Chain Reaction; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2014 |
Impaired resolution of inflammation in human chronic heart failure.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Cardiovascular Diseases; Chronic Disease; Female; Glomerular Filtration Rate; Heart Failure; Humans; Inflammation; Leukocyte Count; Lipoxins; Male; Peroxidase; Risk Factors | 2014 |
Effect of aspirin treatment on the prevention of esophageal adenocarcinoma in a rat experimental model.
Topics: Adenocarcinoma; Animals; Aspirin; Barrett Esophagus; Dinoprostone; Disease Models, Animal; Esophageal Neoplasms; Gastroesophageal Reflux; Gene Expression Regulation, Neoplastic; Humans; Lipoxins; Neoplasms, Experimental; Rats | 2014 |
Aspirin-triggered Lipoxin A4 attenuates mechanical allodynia in association with inhibiting spinal JAK2/STAT3 signaling in neuropathic pain in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Astrocytes; Constriction, Pathologic; Disease Models, Animal; Hyperalgesia; Interleukin-1beta; Interleukin-6; Janus Kinase 2; Lipoxins; Male; Neuralgia; Neuroimmunomodulation; Rats, Sprague-Dawley; RNA, Messenger; Sciatic Nerve; Signal Transduction; Spinal Cord; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Touch; Tumor Necrosis Factor-alpha | 2014 |
Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Aspirin; Cardiotonic Agents; Clopidogrel; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Evaluation, Preclinical; Enzyme Induction; Lipoxins; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type III; Pyrazoles; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Ticagrelor; Ticlopidine; Triazoles; Up-Regulation | 2014 |
Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Bronchoalveolar Lavage Fluid; Cell Communication; Leukocyte Count; Lipopolysaccharides; Lipoxins; Luminescent Proteins; Lung; Male; Mice, Inbred BALB C; Mice, Knockout; Mice, Transgenic; Microscopy, Fluorescence; Neutrophils; Oligopeptides; Platelet Aggregation; Receptors, Formyl Peptide; Survival Analysis; Transfusion Reaction | 2014 |
Regional arterial infusion with lipoxin A4 attenuates experimental severe acute pancreatitis.
Topics: Amylases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cytokines; Heme Oxygenase-1; Inflammation; Infusions, Intra-Arterial; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Lipoxins; Male; Pancreas; Pancreatitis; Peroxidase; Phospholipases A2; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Sprague-Dawley; Taurocholic Acid; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2014 |
The fat and the skinny on acute lung injury.
Topics: Acute Lung Injury; Animals; Aspirin; Lipoxins; Male; Neutrophils; Platelet Aggregation | 2014 |
Aspirin-triggered 15-epi-lipoxin A₄ signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Hyperplasia; Lipoxins; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptors, Formyl Peptide; Tunica Intima | 2015 |
Inflammation activation and resolution in human tendon disease.
Topics: Adolescent; Adult; Arachidonate 15-Lipoxygenase; Aspirin; Female; Humans; Immunohistochemistry; In Vitro Techniques; Inflammation; Interferon-gamma; Interferons; Lectins, C-Type; Lipopolysaccharides; Lipoxins; Male; Mannose Receptor; Mannose-Binding Lectins; NF-kappa B; Receptors, Cell Surface; Receptors, Chemokine; Receptors, Formyl Peptide; Receptors, Lipoxin; STAT6 Transcription Factor; Tendinopathy; Tendons; Young Adult | 2015 |
Aspirin-triggered lipoxin A4 inhibits atherosclerosis progression in apolipoprotein E
Topics: Animals; Aorta; Apolipoproteins E; Aspirin; Atherosclerosis; Cytokines; Female; Lipoxins; Mice, Knockout; Receptors, Formyl Peptide | 2017 |
Non-steroidal anti-inflammatory drugs increase MRP4 expression in an endometriotic epithelial cell line in a PPARa dependent manner.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Diclofenac; Endometriosis; Endometrium; Epithelial Cells; Female; Humans; Italy; Lipoxins; Multidrug Resistance-Associated Proteins; PPAR alpha; RNA, Messenger; RNA, Small Interfering | 2018 |
Aspirin-triggered proresolving mediators stimulate resolution in cancer.
Topics: Animals; Antineoplastic Agents; Aspirin; Chemokine CCL2; Chemokines; Cytokines; Disease Models, Animal; Docosahexaenoic Acids; Eicosanoids; Fatty Acids, Unsaturated; Female; Inflammation; Lipoxins; Macrophages; Metabolomics; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neoplasm Metastasis; Neoplasms; Nerve Tissue Proteins; Phagocytosis; Plasminogen Inactivators; Prostaglandins | 2019 |
Role of aspirin-triggered lipoxin A4, aspirin, and salicylic acid in the modulation of the oxidative and inflammatory responses induced by plasma from women with pre-eclampsia.
Topics: Acetylation; Adolescent; Adult; Aspirin; Cell Adhesion; Cyclooxygenase 2; Female; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lipoxins; Neutrophils; NF-kappa B; Oxidative Stress; Pre-Eclampsia; Pregnancy; Protein Processing, Post-Translational; Salicylic Acid; Thiobarbituric Acid Reactive Substances; Tyrosine; U937 Cells; Young Adult | 2020 |
The 15-Epilipoxin-A4 Pathway with Prophylactic Aspirin in Preventing Preeclampsia: A Longitudinal Cohort Study.
Topics: Adult; Aspirin; Case-Control Studies; Chemoprevention; Cohort Studies; Female; Humans; Lipoxins; Longitudinal Studies; Metabolic Networks and Pathways; Pre-Eclampsia; Pregnancy; Pregnancy, High-Risk | 2020 |
Topical Aspirin Administration Improves Cutaneous Wound Healing in Diabetic Mice Through a Phenotypic Switch of Wound Macrophages Toward an Anti-inflammatory and Proresolutive Profile Characterized by LXA4 Release.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Diabetes Mellitus, Experimental; Inflammation; Leukotriene A4; Leukotriene B4; Lipoxins; Macrophages; Mice; Phenotype; Skin; Wound Healing | 2022 |