aspirin and leukotriene e4

aspirin has been researched along with leukotriene e4 in 86 studies

Research

Studies (86)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.16)	18.7374
1990's	31 (36.05)	18.2507
2000's	31 (36.05)	29.6817
2010's	16 (18.60)	24.3611
2020's	7 (8.14)	2.80

Authors

Authors	Studies
Fitzgerald, GA; Knapp, HR; Sladek, K	1
Björck, T; Dahlén, B; Dahlén, SE; Granström, E; Kumlin, M; Zetterström, O	1
Christie, PE; Hawksworth, RJ; Lee, TH; Smith, CM; Thien, FC	1
Bizzi, B; Castellana, MA; Ciabattoni, G; Landolfi, R; Patrignani, P; Patrono, C; Pogliani, E	1
Black, C; Christie, PE; Ford-Hutchinson, AW; Lee, TH; Markendorf, A; Schmitz-Schumann, M; Tagari, P	1
Arm, JP; Christie, P; Crea, AE; Hawksworth, RJ; Jacques, C; Lee, TH; O'Hickey, SP; Spur, BW	1
Arm, JP; Charlesson, S; Chee, P; Christie, PE; Ford-Hutchinson, AW; Lee, TH; Tagari, P	1
Hamano, S; Ikeda, S; Kikuchi, S; Kojima, M; Komatsu, H; Kusama, H; Okegawa, T; Takehana, Y	1
Krop, I; Lawson, D; Letts, LG; Mehta, J; Mehta, P	1
Bell, GS; Lee, TH; Nasser, SM; Patel, M	1
Arm, JP; Lee, TH	1
Arm, JP; Bell, GS; Foster, S; Lee, TH; MacMillan, R; Nasser, SM; Spruce, KE; Williams, AJ	1
Christie, PE; Lee, TH; Schmitz-Schumann, M; Spur, BW	1
Fauler, J; Frölich, JC; Thon, A; Tsikas, D; von der Hardt, H	1
Hayakawa, T; Kawasaki, A; Kobayashi, M; Maeda, Y; Mita, H; Mizushima, Y; Oosaki, R; Shida, T; Yamada, T	1
Lee, TH	1
Callery, JC; Cohn, J; Drazen, JM; Fischer, AR; Israel, E; Lilly, CM; Rosenberg, MA; Rubin, P; Shapiro, J	1
Christie, PE; Lee, TH	1
Sladek, K; Szczeklik, A	1
Armetti, L; Bianco, S; Folco, GC; Gambaro, G; Pieroni, MG; Refini, RM; Robuschi, M; Sala, A; Sestini, P; Vaghi, A	1
Czech, W; Kapp, A; Schöpf, E	1
Houya, I; Inoue, K; Kimura, I; Kuramitsu, K; Maruo, H; Matsuo, H; Sakamoto, Y; Sakata, K; Shibasaki, M; Tabe, K; Yamamoto, H; Yamamoto, K	1
Akiyama, K; Kobayashi, M; Mita, H; Mizushima, Y; Oosaki, R; Shida, T	1
Kapp, A; Wedi, B	1
Amayasu, H; Nakagawa, H; Onuma, K; Sakamoto, H; Shoji, T; Tajima, T; Yoshida, S	1
Drouet, M; el Founini, M; Sabbah, A	1
Cmiel, A; Dworski, R; Mastalerz, L; Nizankowska, E; Oates, JA; Prokop, A; Sheller, JR; Szczeklik, A	1
Akahori, K; Amayasu, H; Hasegawa, H; Nakabayashi, M; Nakagawa, H; Sakamoto, H; Sakamoto, M; Shoji, T; Tajimab, T; Yamawaki, Y; Yoshida, S	1
Akahori, K; Amayasu, H; Hasegawa, H; Nakagawa, H; Onuma, K; Sakamoto, H; Shoji, T; Yamawaki, Y; Yoshida, S	1
Amayasu, H; Hasegawa, H; Nakagawa, H; Sakamoto, H; Shoji, T; Yoshida, S	1
Daffern, PJ; Hugli, TE; Muilenburg, D; Stevenson, DD	1
Hedman, J; Moilanen, E; Nieminen, MM; Poussa, T	1
Bestyńska-Krypel, A; Cmiel, A; Nizankowska, E; Szczeklik, A	1
Bochenek, G; Mejza, F; Nagraba, K; Nizankowska, E; Swierczynska, M; Szczeklik, A	1
Stern, A	1
Akiyama, K; Endoh, S; Kawagishi, Y; Kobayashi, M; Kudoh, M; Mita, H; Taniguchi, M	1
Mastalerz, L; Nizankowska, E; Sanak, M; Szczeklik, A	1
Bousquet, J; Dahlén, B; Dahlén, SE; Holgate, ST; Kowalski, M; Kuna, P; Lumry, WR; Malmström, K; Nizankowska, E; Pauwels, R; Picado, C; Reiss, TF; Shahane, A; Stevenson, DD; Szczeklik, A; Zhang, J	1
Kawano, T; Kohno, S; Matsuse, H; Mitsuta, K; Obase, Y; Shimoda, T; Tomari, SY	1
Akiyama, K; Higashi, N; Kashii, T; Kawagishi, Y; Kobayashi, M; Maruyama, M; Mita, H; Oosaki, R; Taniguchi, M	1
Cmiel, A; Gawlewicz-Mroczka, A; Mastalerz, L; Nizankowska, E; Szczeklik, A	1
Akiyama, K; Higashi, N; Mita, H; Osame, M; Taniguchi, M	1
Biasi, D; Caruso, C; Corrocher, R; Di Lorenzo, G; Esposito-Pellitteri, M; Pacor, ML; Profita, M; Vignola, AM	1
Cipollone, F; Cuccurullo, F; Di Gregorio, D; Ganci, A; Greco, A; Mezzetti, A; Panara, MR; Pasquale, M; Patrignani, P; Porreca, E	1
Bochenek, G; Nagraba, K; Nizankowska, E; Szczeklik, A	1
Bochenek, G; Dahlén, B; Dahlén, SE; Drupka, D; Gyllfors, P; Isakson, PC; Kumlin, M; Lefkowith, JB; Mejza, F; Murray, JJ; Nizankowska, E; Overholt, J; Sheller, J; Szczeklik, A	1
Gielicz, A; Nizankowska-Mogilnicka, E; Swierczynska, M; Szczeklik, A; Zarychta, J	1
Mastalerz, L; Radziszewski, W; Setkowicz, M; Szczeklik, A; Zembowicz, A	1
Chazan, R; Rubinsztajn, R; Wrońska, J	1
Akiyama, K; Higashi, A; Higashi, N; Ishii, T; Kawagishi, Y; Mita, H; Osame, M; Taniguchi, M	1
Mastalerz, L; Sanak, M; Setkowicz, M; Szczeklik, A	1
Akiyama, K; Higashi, A; Higashi, N; Kawagishi, Y; Mita, H; Taniguchi, M	1
Akiyama, K; Higashi, A; Higashi, N; Mita, H; Taniguchi, M	1
Fukushima, C; Kawano, T; Kohno, S; Kondo, Y; Machida, I; Matsuse, H; Mitsuta, K; Obase, Y; Saeki, S; Shimoda, T; Tomari, S	1
Bochenek, G; Kiełbasa, B; Sanak, M; Szczeklik, A	1
Baldassarre, S; Choufani, G; Michils, A; Schandene, L	1
Dal Negro, RW; Facchini, FM; Micheletto, C; Tognella, S; Visconti, M	1
Dal Negro, RW; Micheletto, C; Tognella, S; Trevisan, F; Visconti, M	2
Mastalerz, L; Nizankowska-Mogilnicka, E; Sanak, M; Sokolowska, B; Szczeklik, W	1
Mastalerz, L; Podolec-Rubis, M; Sanak, M; Setkowicz, M; Szczeklik, A	1
Akiyama, K; Higashi, N; Mita, H; Ono, E; Taniguchi, M	1
Farooque, SP; Lee, TH; Woszczek, G	1
Bertacco, S; Dal Negro, RW; Micheletto, C; Tognella, S; Trevisan, F; Visconti, M	1
Bartra, J; Muñoz-Cano, R; Picado, C; Roca, J; Sánchez-López, J; Serrano, C; Valero, A	1
Akiyama, K; Higashi, N; Komase, Y; Mita, H; Miyazawa, T; Nakagawa, T; Ono, E; Taniguchi, M; Yamaguchi, H	1
Bhattacharyya, N; Boyce, JA; Castells, MC; Chhay, H; Kidder, MS; Laidlaw, TM; Milne, GL; Shen, S; Xing, W	1
Celejewska-Wójcik, N; Cybulska, A; Hartwich, P; Hydzik-Sobocińska, K; Januszek, R; Mastalerz, L; Nieckarz, R; Oleś, K; Sanak, M; Stręk, P; Szaleniec, J; Wójcik, K	1
Czlonkowski, A; Filipiak, KJ; Janicki, PK; Kaplon-Cieslicka, A; Kondracka, A; Kosior, DA; Opolski, G; Postula, M; Rosiak, M; Trzepla, E; Zaremba, M	1
Bochenek, G; Ćmiel, A; Gielicz, A; Niżankowska-Mogilnicka, E; Plutecka, H; Sanak, M; Stręk, P; Świerczyńska-Krępa, M; Szczeklik, A	1
Akiyama, K; Fukutomi, Y; Hayashi, H; Higashi, N; Ito, J; Kajiwara, K; Mita, H; Mitsui, C; Ono, E; Sekiya, K; Taniguchi, M; Tsuburai, T; Yamamoto, K	1
Celejewska-Wójcik, N; Gielicz, A; Januszek, R; Kaszuba, M; Mastalerz, L; Oleś, K; Plutecka, H; Sanak, M; Stręk, P; Wójcik, K	1
Bachert, C; De Ruyck, N; Derycke, L; Holtappels, G; Niżankowska-Mogilnicka, E; Pérez-Novo, CA; Pezato, R; Sanak, M; Świerczyńska-Krępa, M; Van Crombruggen, K	1
Hudes, G; Jerschow, E; Morales, E; Ren, Z; Rosenstreich, D; Sanak, M; Schuster, V; Spivack, SD	1
Aronica, MA; Hazen, SL; Lang, DM; Maierson, ES; Vasas, DC; Wang, XF	1
Higashi, N; Ishii, T; Okamoto, M; Taniguchi, M; Yamaguchi, T; Yamamoto, K	1
Buczek, M; Ćmiel, A; Ignacak, M; Konduracka, E; Kot, A; Mastalerz, L; Mejza, F; Oleś, K; Sanak, M; Tyrak, KE	1
Ayuso, P; Bartra, J; Bogas-Herrera, G; Campo, P; Cornejo-García, JA; Doña, I; Jurado-Escobar, R; Pérez-Sánchez, N; Perkins, JR; Plaza-Serón, MC; Sanak, M; Torres, MJ	1
Butterfield, J; Castells, M	1
Fukutomi, Y; Hamada, Y; Hasegawa, Y; Hashimoto, N; Hayashi, H; Izuhara, K; Kajiwara, K; Kamide, Y; Mitsui, C; Nakamura, Y; Sekiya, K; Taniguchi, M; Tomita, Y; Tsuburai, T; Wakahara, K; Watai, K	1
Bochenek, G; Gielicz, A; Jakiela, B; Plutecka, H; Przybyszowski, M; Rebane, A; Sladek, K; Soja, J	1
Ban, GY; Choi, Y; Kim, YK; Lee, DH; Lee, HR; Park, HS; Shin, YS; Sim, S	1
Idler, BM; Lal, D; Marino, MJ	1
Amin, T; Boyce, JA; Buchheit, KM; Cahill, KN; Gapko, D; Laidlaw, TM; Lewis, E; Milne, GL; Murphy, K; Singer, J; Wu, P	1
Calder, PC; Curtis, PJ; Loke, Y; Marquette, M; Tailor, BV; Wilson, AM	1
Boyce, JA; Buchheit, KM; Cahill, KN; Chen, CC; Cho, L; Cui, J; Feng, C; Hacker, J; Israel, E; Laidlaw, TM; Le, M	1

Reviews

6 review(s) available for aspirin and leukotriene e4

Article	Year
Sulphidopeptide leukotrienes in asthma. Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A Topics: Animals; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Guinea Pigs; Histamine; Humans; Leukotriene E4; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; SRS-A; Trachea	1991
Evidence for a specific role of leukotriene E4 in asthma and airway hyperresponsiveness. Advances in prostaglandin, thromboxane, and leukotriene research, 1994, Volume: 22 Topics: Animals; Aspirin; Asthma; Constriction, Pathologic; Humans; Leukotriene E4; Leukotrienes; Respiratory System	1994
Hyperleukotrieneuria in patients with allergic and inflammatory disease. Allergology international : official journal of the Japanese Society of Allergology, 2008, Volume: 57, Issue:4 Topics: Aspirin; Asthma; Biomarkers; Cell Movement; Drug Hypersensitivity; Eosinophils; Gene Expression Regulation; Inflammation; Leukotriene E4; Nasal Polyps; Risk Factors; Vasculitis	2008
Leukotriene E4: perspective on the forgotten mediator. The Journal of allergy and clinical immunology, 2009, Volume: 124, Issue:3 Topics: Animals; Aspirin; Asthma; Bronchial Hyperreactivity; Drug Hypersensitivity; Histamine; Humans; Leukotriene C4; Leukotriene D4; Leukotriene E4; Methacholine Chloride; Receptors, Leukotriene; Skin	2009
Mast Cell Activation Syndrome and Mastocytosis: Initial Treatment Options and Long-Term Management. The journal of allergy and clinical immunology. In practice, 2019, Volume: 7, Issue:4 Topics: Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cromolyn Sodium; Disease Management; Glucocorticoids; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyurea; Interleukin-6; Leukotriene Antagonists; Leukotriene E4; Mastocytosis; Omalizumab; Prostaglandin D2; Tryptases	2019
Urinary Leukotriene E4 as a Biomarker in NSAID-Exacerbated Respiratory Disease (N-ERD): a Systematic Review and Meta-analysis. Current allergy and asthma reports, 2022, Volume: 22, Issue:12 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Leukotriene E4	2022

Trials

26 trial(s) available for aspirin and leukotriene e4

Article	Year
Urinary leukotriene E4 after lysine-aspirin inhalation in asthmatic subjects. The American review of respiratory disease, 1992, Volume: 146, Issue:6 Topics: Administration, Inhalation; Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Lysine; Male; Middle Aged; SRS-A	1992
Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects. The American review of respiratory disease, 1991, Volume: 143, Issue:5 Pt 1 Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Male; Methacholine Chloride; Middle Aged; SRS-A	1991
Effect of the 5-lipoxygenase inhibitor ZD2138 on aspirin-induced asthma. Thorax, 1994, Volume: 49, Issue:8 Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Calcimycin; Double-Blind Method; Female; Forced Expiratory Volume; Humans; In Vitro Techniques; Leukotriene E4; Lipoxygenase Inhibitors; Male; Middle Aged; Pyrans; Quinolones	1994
The pivotal role of 5-lipoxygenase products in the reaction of aspirin-sensitive asthmatics to aspirin. The American review of respiratory disease, 1993, Volume: 148, Issue:6 Pt 1 Topics: Adult; Arachidonate 5-Lipoxygenase; Aspirin; Asthma; Bronchoconstriction; Double-Blind Method; Drug Hypersensitivity; Female; Forced Expiratory Volume; Humans; Hydroxyurea; Leukotriene E4; Lipoxygenase Inhibitors; Male; Middle Aged	1993
Inhaled PGE2 prevents aspirin-induced bronchoconstriction and urinary LTE4 excretion in aspirin-sensitive asthma. American journal of respiratory and critical care medicine, 1996, Volume: 153, Issue:2 Topics: Administration, Inhalation; Adolescent; Adult; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Chromatography, High Pressure Liquid; Dinoprostone; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Lysine; Male; Middle Aged	1996
Cromolyn sodium prevents bronchoconstriction and urinary LTE4 excretion in aspirin-induced asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1998, Volume: 80, Issue:2 Topics: Administration, Inhalation; Adult; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchi; Bronchoconstriction; Creatinine; Cromolyn Sodium; Dipyrone; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Male; Middle Aged; Respiratory Function Tests; Vital Capacity	1998
Salmeterol prevents aspirin-induced attacks of asthma and interferes with eicosanoid metabolism. American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:4 Topics: Administration, Inhalation; Adrenergic beta-Agonists; Adult; Albuterol; Aspirin; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchodilator Agents; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method; Eicosanoids; Eosinophils; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Lysine; Male; Middle Aged; Placebos; Prostaglandin D2; Prostaglandins D; Salmeterol Xinafoate	1998
Bronchial hyperresponsiveness, hypersensitivity to analgesics and urinary leukotriene E4 excretion in patients with aspirin-intolerant asthma. International archives of allergy and immunology, 1998, Volume: 117, Issue:2 Topics: Adult; Anti-Asthmatic Agents; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Chromatography, High Pressure Liquid; Cromolyn Sodium; Cross-Over Studies; Dipyrone; Double-Blind Method; Female; Humans; Leukotriene E4; Male; Methacholine Chloride; Middle Aged	1998
Effect of acyclovir on bronchoconstriction and urinary leukotriene E4 excretion in aspirin-induced asthma. The Journal of allergy and clinical immunology, 1998, Volume: 102, Issue:6 Pt 1 Topics: Acyclovir; Administration, Oral; Adult; Anti-Asthmatic Agents; Aspirin; Asthma; Bronchoconstriction; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Male; Middle Aged; Vital Capacity	1998
Anti-inflammatory effect of roxithromycin in patients with aspirin-intolerant asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1999, Volume: 29, Issue:7 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Blood Proteins; Bronchial Hyperreactivity; Bronchial Provocation Tests; Chromatography, High Pressure Liquid; Cross-Over Studies; Dipyrone; Double-Blind Method; Eosinophil Granule Proteins; Eosinophils; Female; Humans; Leukotriene E4; Male; Middle Aged; Ribonucleases; Roxithromycin	1999
Oral and bronchial provocation tests with aspirin for diagnosis of aspirin-induced asthma. The European respiratory journal, 2000, Volume: 15, Issue:5 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Female; Humans; Leukotriene E4; Lysine; Male; Middle Aged; Mouth	2000
Safety of a specific COX-2 inhibitor in aspirin-induced asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2001, Volume: 31, Issue:2 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Cross-Over Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Isoenzymes; Lactones; Leukotriene E4; Male; Membrane Proteins; Middle Aged; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Sulfones	2001
Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial. American journal of respiratory and critical care medicine, 2002, Jan-01, Volume: 165, Issue:1 Topics: Acetates; Administration, Oral; Adult; Aged; Anti-Asthmatic Agents; Aspirin; Asthma; Cyclopropanes; Double-Blind Method; Drug Hypersensitivity; Drug Monitoring; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotriene E4; Male; Middle Aged; Peak Expiratory Flow Rate; Quality of Life; Quinolines; Sulfides; Treatment Outcome	2002
Protection against exercise-induced bronchoconstriction by montelukast in aspirin-sensitive and aspirin-tolerant patients with asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2002, Volume: 32, Issue:9 Topics: Acetates; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Exercise-Induced; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Hypersensitivity; Exercise Test; Female; Forced Expiratory Volume; Humans; Leukotriene Antagonists; Leukotriene E4; Lung; Male; Middle Aged; Quinolines; Sulfides	2002
Modulation of aspirin-insensitive eicosanoid biosynthesis by 6-methylprednisolone in unstable angina. Circulation, 2003, Jan-07, Volume: 107, Issue:1 Topics: Adult; Angina, Unstable; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Double-Blind Method; Eicosanoids; Female; Glucocorticoids; Humans; Leukotriene E4; Male; Methylprednisolone; Middle Aged; Myocardial Ischemia; Thromboxane B2	2003
Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgetic drug celecoxib. The Journal of allergy and clinical immunology, 2003, Volume: 111, Issue:5 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Celecoxib; Cross-Over Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Hypersensitivity; Female; Humans; Isoenzymes; Leukotriene E4; Male; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides	2003
Nasal versus bronchial and nasal response to oral aspirin challenge: Clinical and biochemical differences between patients with aspirin-induced asthma/rhinitis. The Journal of allergy and clinical immunology, 2003, Volume: 112, Issue:5 Topics: Administration, Oral; Adult; Aspirin; Asthma; Bronchi; Dinoprost; Female; Humans; Leukotriene E4; Male; Nasal Cavity; Rhinitis; Severity of Illness Index; Single-Blind Method	2003
Safety of cyclooxygenase 2 inhibitors and increased leukotriene synthesis in chronic idiopathic urticaria with sensitivity to nonsteroidal anti-inflammatory drugs. Archives of dermatology, 2003, Volume: 139, Issue:12 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biopsy; Celecoxib; Computer Graphics; Cross-Over Studies; Cyclooxygenase Inhibitors; Cysteine; Double-Blind Method; Drug Eruptions; Female; Humans; Lactones; Leukotriene E4; Leukotrienes; Male; Middle Aged; Multivariate Analysis; Naproxen; Prospective Studies; Pyrazoles; Serine Endopeptidases; Skin; Sulfonamides; Sulfones; Treatment Outcome; Tryptases; Urticaria	2003
Hypersensitivity to aspirin: common eicosanoid alterations in urticaria and asthma. The Journal of allergy and clinical immunology, 2004, Volume: 113, Issue:4 Topics: Adult; Alleles; Aspirin; Asthma; Dinoprost; Drug Hypersensitivity; Eicosanoids; Female; Genotype; Glutathione Transferase; Humans; Leukotriene E4; Male; Middle Aged; Polymorphism, Single Nucleotide; Single-Blind Method; Urticaria	2004
Tacrolimus reduces urinary excretion of leukotriene E(4) and inhibits aspirin-induced asthma to threshold dose of aspirin. The Journal of allergy and clinical immunology, 2004, Volume: 114, Issue:6 Topics: Adult; Aspirin; Asthma; ATP Binding Cassette Transporter, Subfamily B; Bronchoconstriction; Cross-Over Studies; Double-Blind Method; Eosinophil Cationic Protein; Female; Humans; Immunosuppressive Agents; Leukotriene E4; Male; Middle Aged; Tacrolimus	2004
Safety of parecoxib in asthmatic patients with aspirin-exacerbated respiratory disease. International archives of allergy and immunology, 2011, Volume: 156, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; Cyclooxygenase 2 Inhibitors; Female; Forced Expiratory Volume; Humans; Isoxazoles; Leukotriene E4; Male; Middle Aged; Nasal Provocation Tests	2011
Aspirin desensitization in patients with aspirin-induced and aspirin-tolerant asthma: a double-blind study. The Journal of allergy and clinical immunology, 2014, Volume: 134, Issue:4 Topics: Administration, Oral; Adult; Aged; Allergens; Aspirin; Asthma; Asthma, Aspirin-Induced; Chronic Disease; Desensitization, Immunologic; Dinoprost; Double-Blind Method; Eosinophils; Female; Follow-Up Studies; Humans; Leukotriene E4; Male; Middle Aged; Nasal Polyps; Pilot Projects; Prostaglandin D2; Rhinitis; Sinusitis; Spirometry; Treatment Outcome	2014
Systemic expression of inflammatory mediators in patients with chronic rhinosinusitis and nasal polyps with and without Aspirin Exacerbated Respiratory Disease. Cytokine, 2016, Volume: 77 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; Chronic Disease; Cytokines; Female; Humans; Immunoenzyme Techniques; Inflammation Mediators; Leukotriene E4; Male; Middle Aged; Nasal Polyps; Prostaglandin D2; Rhinitis; Single-Blind Method; Sinusitis; T-Lymphocyte Subsets	2016
Utility of low-dose oral aspirin challenges for diagnosis of aspirin-exacerbated respiratory disease. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2016, Volume: 116, Issue:4 Topics: Administration, Oral; Adult; Allergens; Aspirin; Asthma, Aspirin-Induced; Drug Hypersensitivity; Female; Humans; Immunization; Leukotriene E4; Male; Middle Aged; Nitric Oxide; Sensitivity and Specificity	2016
Omalizumab can inhibit respiratory reaction during aspirin desensitization. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2018, Volume: 121, Issue:1 Topics: Adult; Anti-Asthmatic Agents; Aspirin; Asthma, Aspirin-Induced; Biomarkers; Bronchial Spasm; Desensitization, Immunologic; Double-Blind Method; Drug Administration Schedule; Female; Humans; Leukotriene E4; Male; Middle Aged; Omalizumab	2018
Omalizumab for Aspirin Hypersensitivity and Leukotriene Overproduction in Aspirin-exacerbated Respiratory Disease. A Randomized Controlled Trial. American journal of respiratory and critical care medicine, 2020, 06-15, Volume: 201, Issue:12 Topics: Adult; Aged; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aspirin; Asthma, Aspirin-Induced; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Male; Middle Aged; Omalizumab; Prostaglandin D2; Young Adult	2020

Other Studies

54 other study(ies) available for aspirin and leukotriene e4

Article	Year
Increased excretion of leukotriene E4 during aspirin-induced asthma. The Journal of laboratory and clinical medicine, 1992, Volume: 119, Issue:1 Topics: Aspirin; Asthma; Creatinine; Dose-Response Relationship, Drug; Humans; Leukotriene E4; SRS-A	1992
Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmatics. The American review of respiratory disease, 1992, Volume: 146, Issue:1 Topics: Adult; Allergens; Aspirin; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Leukotriene E4; Male; Middle Aged; SRS-A; Thromboxane B2	1992
Urinary leukotriene E4 in bronchial asthma. The European respiratory journal, 1992, Volume: 5, Issue:6 Topics: Adult; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Drug Hypersensitivity; Female; Histamine; Humans; Leukotriene E4; Male; SRS-A	1992
Increased thromboxane biosynthesis in patients with polycythemia vera: evidence for aspirin-suppressible platelet activation in vivo. Blood, 1992, Oct-15, Volume: 80, Issue:8 Topics: Adult; Aged; Aspirin; Blood Platelets; Female; Humans; Kinetics; Leukotriene E4; Male; Middle Aged; Platelet Activation; Polycythemia Vera; SRS-A; Thromboxane A2; Thromboxane B2	1992
Effect of a thromboxane A2 synthetase inhibitor (OKY-046.HCl) on airway hyperresponsiveness in guinea pigs. European journal of pharmacology, 1990, Aug-02, Volume: 184, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Airway Resistance; Animals; Antigens; Aspirin; Bronchoalveolar Lavage Fluid; Guinea Pigs; Leukotriene E4; Methacrylates; N-Formylmethionine Leucyl-Phenylalanine; Phthalazines; Physostigmine; Platelet Activating Factor; Propranolol; Respiratory System; SRS-A; Thromboxane B2; Thromboxane-A Synthase	1990
Leukotrienes potentiate the effects of epinephrine and thrombin on human platelet aggregation. Thrombosis research, 1986, Mar-01, Volume: 41, Issue:5 Topics: Aspirin; Calcium; Drug Synergism; Epinephrine; Humans; Leukotriene E4; Methacrylates; Platelet Aggregation; SRS-A; Thrombin; Thromboxane A2; Time Factors	1986
The effect of aspirin desensitization on urinary leukotriene E4 concentrations in aspirin-sensitive asthma. American journal of respiratory and critical care medicine, 1995, Volume: 151, Issue:5 Topics: Adult; Aspirin; Asthma; Creatinine; Desensitization, Immunologic; Drug Hypersensitivity; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Male; Middle Aged	1995
Airway responsiveness to leukotriene C4 (LTC4), leukotriene E4 (LTE4) and histamine in aspirin-sensitive asthmatic subjects. The European respiratory journal, 1993, Volume: 6, Issue:10 Topics: Adolescent; Adult; Aspirin; Asthma; Female; Forced Expiratory Volume; Histamine; Humans; Leukotriene C4; Leukotriene E4; Lysine; Male; Middle Aged; Respiratory System	1993
Enhanced synthesis of cysteinyl leukotrienes in juvenile rheumatoid arthritis. Arthritis and rheumatism, 1994, Volume: 37, Issue:1 Topics: Adolescent; Adult; Arthritis, Juvenile; Aspirin; Child; Gas Chromatography-Mass Spectrometry; Humans; Leukotriene C4; Leukotriene D4; Leukotriene E4; Thromboxane B2	1994
[Fundamental studies on the measurement of urinary leukotriene E4]. Arerugi = [Allergy], 1994, Volume: 43, Issue:2 Pt 1 Topics: Aspirin; Asthma; Chromatography, High Pressure Liquid; Drug Hypersensitivity; Humans; Immunoenzyme Techniques; Leukotriene E4	1994
Mechanism of bronchospasm in aspirin-sensitive asthma. The American review of respiratory disease, 1993, Volume: 148, Issue:6 Pt 1 Topics: Animals; Aspirin; Asthma; Bronchoconstriction; Drug Hypersensitivity; Guinea Pigs; Humans; Leukotriene E4; Prostaglandin-Endoperoxide Synthases	1993
Leukotrienes and aspirin induced asthma. Thorax, 1993, Volume: 48, Issue:12 Topics: Aspirin; Asthma; Humans; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes	1993
Cysteinyl leukotrienes overproduction and mast cell activation in aspirin-provoked bronchospasm in asthma. The European respiratory journal, 1993, Volume: 6, Issue:3 Topics: Adult; Aspirin; Asthma; Blood Proteins; Bronchial Provocation Tests; Bronchoconstriction; Chymases; Eosinophil Granule Proteins; Eosinophils; Female; Humans; Leukotriene E4; Male; Mast Cells; Methacholine Chloride; Middle Aged; Ribonucleases; Serine Endopeptidases; SRS-A; Thromboxane B2; Tryptases	1993
Release of sulfidoleukotrienes in vitro: its relevance in the diagnosis of pseudoallergy to acetylsalicylic acid. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:7 Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antigen-Antibody Reactions; Aspirin; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Female; Humans; In Vitro Techniques; Leukocytes; Leukotriene C4; Leukotriene D4; Leukotriene E4; Leukotrienes; Male; Middle Aged	1995
[Clinical evaluation of urinary leukotriene E4 levels in asymptomatic bronchial asthma]. Arerugi = [Allergy], 1996, Volume: 45, Issue:10 Topics: Adult; Aspirin; Asthma; Humans; Leukotriene E4	1996
Urinary leukotriene E4 and 11-dehydrothromboxane B2 in patients with aspirin-sensitive asthma. Allergy, 1997, Volume: 52, Issue:4 Topics: Aspirin; Asthma; Case-Control Studies; Drug Hypersensitivity; Female; Humans; Leukotriene E4; Male; Middle Aged; Severity of Illness Index; Thromboxane B2	1997
[Value of the cellular antigen stimulation test (CAST)]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1997, Volume: 48, Issue:5 Topics: Antigens; Aspirin; Drug Eruptions; Enzyme-Linked Immunosorbent Assay; Humans; Leukocytes; Leukotriene C4; Leukotriene D4; Leukotriene E4	1997
[Importance of the urinary leukotriene E4 level. Preliminary study]. Allergie et immunologie, 1998, Volume: 30, Issue:6 Topics: Acetaminophen; Anaphylaxis; Anesthetics; Aspirin; Biomarkers; Chymases; Drug Hypersensitivity; Histamine; Humans; Leukotriene C4; Leukotriene E4; Postoperative Complications; Serine Endopeptidases; Tryptases	1998
Association of urinary leukotriene E4 excretion during aspirin challenges with severity of respiratory responses. The Journal of allergy and clinical immunology, 1999, Volume: 104, Issue:3 Pt 1 Topics: Adult; Aspirin; Asthma; Drug Hypersensitivity; Humans; Leukotriene E4; Middle Aged	1999
Serum ECP and MPO, but not urinary LTE4, are associated with bronchial hyper-responsiveness. Respiratory medicine, 1999, Volume: 93, Issue:8 Topics: Adult; Aged; Aspirin; Biomarkers; Blood Proteins; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Eosinophil Granule Proteins; Eosinophils; Female; Humans; Leukotriene E4; Male; Methacholine Chloride; Middle Aged; Peroxidase; Ribonucleases; Smoking	1999
[Cellular antigen stimulation test (CAST). A new possibility in diagnosis of aspirin-sensitivity rhinosinusitis?]. HNO, 2001, Volume: 49, Issue:3 Topics: Aspirin; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Humans; Leukocytes; Leukotriene C4; Leukotriene D4; Leukotriene E4; Rhinitis, Allergic, Perennial; Sensitivity and Specificity; Sinusitis	2001
Possible involvement of mast-cell activation in aspirin provocation of aspirin-induced asthma. Allergy, 2001, Volume: 56, Issue:11 Topics: Adult; Aged; Aspirin; Asthma; Bronchial Provocation Tests; Cyclooxygenase Inhibitors; Dinoprost; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Male; Mast Cells; Methylhistamines; Middle Aged; Sensitivity and Specificity; Thromboxane A2; Thromboxane B2; Time Factors	2001
Montelukast for persistent asthma. Lancet (London, England), 2001, Oct-27, Volume: 358, Issue:9291 Topics: Acetates; Anti-Asthmatic Agents; Aspirin; Asthma; Cyclopropanes; Humans; Leukotriene E4; Prednisone; Quinolines; Sulfides	2001
Effects of pranlukast on chemical mediators in induced sputum on provocation tests in atopic and aspirin-intolerant asthmatic patients. Chest, 2002, Volume: 121, Issue:1 Topics: Adult; Anti-Asthmatic Agents; Aspirin; Asthma; Blood Proteins; Bronchial Provocation Tests; Chromones; Drug Hypersensitivity; Eosinophil Granule Proteins; Eosinophils; Female; Forced Expiratory Volume; Humans; Leukocyte Count; Leukotriene D4; Leukotriene E4; Male; Middle Aged; Ribonucleases; Thromboxane B2	2002
Leukotriene C4 synthase promoter polymorphism in Japanese patients with aspirin-induced asthma. The Journal of allergy and clinical immunology, 2002, Volume: 109, Issue:6 Topics: Aspirin; Asthma; Drug Hypersensitivity; Eosinophils; Female; Gene Frequency; Genotype; Glutathione Transferase; Humans; Japan; Leukotriene E4; Male; Middle Aged; Polymorphism, Genetic; Promoter Regions, Genetic	2002
A comparative study of eicosanoid concentrations in sputum and urine in patients with aspirin-intolerant asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2002, Volume: 32, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Drug Hypersensitivity; Eicosanoids; Eosinophil-Derived Neurotoxin; Eosinophils; Female; Humans; Leukocyte Count; Leukotriene E4; Male; Middle Aged; Prostaglandin D2; Rhinitis; Ribonucleases; Sinusitis; Sputum	2002
Urinary metabolites of histamine and leukotrienes before and after placebo-controlled challenge with ASA and food additives in chronic urticaria patients. Allergy, 2002, Volume: 57, Issue:12 Topics: Administration, Oral; Adult; Aspirin; Biomarkers; Bronchoconstrictor Agents; Chronic Disease; Controlled Clinical Trials as Topic; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Hypersensitivity; Female; Food Additives; Humans; Italy; Leukotriene E4; Male; Methylhistamines; Middle Aged; Sodium Benzoate; Sodium Glutamate; Sulfites; Tartrazine; Time Factors; Urticaria	2002
A controlled study of 9alpha,11beta-PGF2 (a prostaglandin D2 metabolite) in plasma and urine of patients with bronchial asthma and healthy controls after aspirin challenge. The Journal of allergy and clinical immunology, 2003, Volume: 111, Issue:4 Topics: Adult; Aged; Aspirin; Asthma; Dinoprost; Female; Humans; Leukotriene E4; Male; Middle Aged; Prostaglandin D2; Serine Endopeptidases; Tryptases	2003
[Urinary leukotriene E4 concentration in patients with bronchial asthma and intolerance of non-steroids anti-inflammatory drugs before and after oral aspirin challenge]. Polskie Archiwum Medycyny Wewnetrznej, 2003, Volume: 110, Issue:2 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Provocation Tests; Drug Hypersensitivity; Female; Humans; Leukotriene E4; Male; Middle Aged	2003
Clinical features of asthmatic patients with increased urinary leukotriene E4 excretion (hyperleukotrienuria): Involvement of chronic hyperplastic rhinosinusitis with nasal polyposis. The Journal of allergy and clinical immunology, 2004, Volume: 113, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Chronic Disease; Female; Humans; Leukotriene E4; Male; Middle Aged; Nasal Polyps; Rhinitis; Sinusitis	2004
Urinary 3-bromotyrosine and 3-chlorotyrosine concentrations in asthmatic patients: lack of increase in 3-bromotyrosine concentration in urine and plasma proteins in aspirin-induced asthma after intravenous aspirin challenge. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Blood Proteins; Bronchial Provocation Tests; Case-Control Studies; Eosinophils; Gas Chromatography-Mass Spectrometry; Humans; Leukocyte Count; Leukotriene E4; Neutrophils; Tyrosine	2004
Increase in urinary leukotriene B4 glucuronide concentration in patients with aspirin-intolerant asthma after intravenous aspirin challenge. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:8 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Female; Glucuronides; Humans; Leukotriene B4; Leukotriene E4; Male; Middle Aged; Statistics, Nonparametric	2004
Exhaled eicosanoids following oral aspirin challenge in asthmatic patients. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:12 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aspirin; Asthma; Biomarkers; Breath Tests; Case-Control Studies; Dinoprost; Dinoprostone; Eicosanoids; Female; Gas Chromatography-Mass Spectrometry; Humans; Leukotriene E4; Lung; Male; Middle Aged; ROC Curve	2004
Asthma attacks induced by low doses of celecoxib, aspirin, and acetaminophen. The Journal of allergy and clinical immunology, 2006, Volume: 117, Issue:1 Topics: Acetaminophen; Aspirin; Asthma; Celecoxib; Cyclooxygenase Inhibitors; Female; Humans; Leukotriene E4; Middle Aged; Pyrazoles; Sulfonamides	2006
Aspirin induced asthma (AIA) with nasal polyps has the highest basal LTE4 excretion: a study vs AIA without polyps, mild topic asthma, and normal controls. European annals of allergy and clinical immunology, 2006, Volume: 38, Issue:1 Topics: Adult; Aspirin; Asthma; Biomarkers; Bronchial Provocation Tests; Humans; Leukotriene E4; Middle Aged; Nasal Polyps; Rhinitis	2006
Changes in urinary LTE4 and nasal functions following nasal provocation test with ASA in ASA-tolerant and -intolerant asthmatics. Respiratory medicine, 2006, Volume: 100, Issue:12 Topics: Administration, Intranasal; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Male; Middle Aged; Nasal Cavity; Nasal Provocation Tests; Nose; Rhinometry, Acoustic	2006
Urinary LTE4 is higher after nasal provocation test with L-ASA in bronchial than in only nasal responders. European annals of allergy and clinical immunology, 2007, Volume: 39, Issue:5 Topics: Adult; Aspirin; Asthma; Bronchial Hyperreactivity; Cysteine; Female; Forced Expiratory Volume; Humans; Leukotriene E4; Leukotrienes; Lysine; Male; Middle Aged; Nasal Cavity; Nasal Provocation Tests; Rhinometry, Acoustic	2007
Aspirin tolerance and leukotriene biosynthesis in Churg-Strauss syndrome. Allergy, 2008, Volume: 63, Issue:7 Topics: Adult; Aspirin; Churg-Strauss Syndrome; Drug Tolerance; Eosinophils; Female; Humans; Leukotriene E4; Male; Middle Aged	2008
Clinical course and urinary eicosanoids in patients with aspirin-induced urticaria followed up for 4 years. The Journal of allergy and clinical immunology, 2009, Volume: 123, Issue:1 Topics: Adult; Aspirin; Cyclooxygenase Inhibitors; Dinoprost; Drug Eruptions; Female; Follow-Up Studies; Humans; Leukotriene E4; Male; Middle Aged; Urticaria	2009
The prevalence of nasal polyps and the corresponding urinary LTE4 levels in severe compared to mild and moderate asthma. European annals of allergy and clinical immunology, 2010, Volume: 42, Issue:3 Topics: Adolescent; Adult; Aged; Aspirin; Asthma; Cohort Studies; Female; Humans; Leukotriene E4; Male; Middle Aged; Nasal Polyps; Prevalence	2010
Urinary concentrations of 15-epimer of lipoxin A(4) are lower in patients with aspirin-intolerant compared with aspirin-tolerant asthma. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2011, Volume: 41, Issue:12 Topics: Adult; Aged; Aspirin; Asthma, Aspirin-Induced; Female; Humans; Leukotriene E4; Lipoxins; Male; Middle Aged; ROC Curve	2011
Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes. Blood, 2012, Apr-19, Volume: 119, Issue:16 Topics: Adult; Aged; Arachidonate 5-Lipoxygenase; Aspirin; Asthma, Aspirin-Induced; Blood Platelets; Bronchoconstriction; Cysteine; Female; Granulocytes; Humans; Integrins; Leukocytes; Leukotriene E4; Leukotrienes; Male; Middle Aged; Nasal Polyps; Platelet Aggregation Inhibitors; Young Adult	2012
Incidence of aspirin hypersensitivity in patients with chronic rhinosinusitis and diagnostic value of urinary leukotriene E4. Polskie Archiwum Medycyny Wewnetrznej, 2012, Volume: 122, Issue:9 Topics: Adult; Aspirin; Asthma; Chronic Disease; Drug Hypersensitivity; Female; Humans; Leukotriene E4; Male; Middle Aged; Rhinitis; Sinusitis	2012
Lack of effect of common single nucleotide polymorphisms in leukotriene pathway genes on platelet reactivity in patients with diabetes. Molecular medicine reports, 2013, Volume: 8, Issue:3 Topics: 5-Lipoxygenase-Activating Proteins; Aged; Alleles; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Aspirin; Blood Platelets; Cohort Studies; Diabetes Mellitus, Type 2; Epoxide Hydrolases; Female; Gene Frequency; Genotype; Glutathione Transferase; Humans; Leukotriene B4; Leukotriene E4; Male; Middle Aged; Polymorphism, Single Nucleotide	2013
Platelet activation markers overexpressed specifically in patients with aspirin-exacerbated respiratory disease. The Journal of allergy and clinical immunology, 2016, Volume: 137, Issue:2 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; Biomarkers; Blood Platelets; Comorbidity; Female; Gene Expression; Humans; Immunophenotyping; Leukotriene E4; Male; Middle Aged; Platelet Activation; Respiration Disorders; Risk Factors	2016
Aspirin provocation increases 8-iso-PGE2 in exhaled breath condensate of aspirin-hypersensitive asthmatics. Prostaglandins & other lipid mediators, 2015, Volume: 121, Issue:Pt B Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Biomarkers; Breath Tests; Bronchial Provocation Tests; Bronchoconstriction; Cyclooxygenase Inhibitors; Dinoprostone; Female; Forced Expiratory Volume; Humans; Isoprostanes; Leukotriene E4; Lung; Lysine; Male; Middle Aged; Respiratory Mucosa; Severity of Illness Index; Single-Blind Method	2015
Differences in urinary leukotriene E4 levels and distribution of eosinophils between chronic rhinosinusitis patients with aspirin-intolerant and-tolerant asthma. Nihon Jibiinkoka Gakkai kaiho, 2016, Volume: 119, Issue:12 Topics: Aspirin; Asthma; Chronic Disease; Drug Tolerance; Eosinophils; Humans; Leukotriene E4; Rhinitis; Sinusitis	2016
Prostaglandin E Allergy, 2019, Volume: 74, Issue:5 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Asthma, Aspirin-Induced; Biomarkers; Dinoprostone; Disease Susceptibility; Female; Humans; Leukotriene E4; Male; Middle Aged; Phenotype; Respiratory Function Tests; Sputum	2019
Eicosanoid mediator profiles in different phenotypes of nonsteroidal anti-inflammatory drug-induced urticaria. Allergy, 2019, Volume: 74, Issue:6 Topics: Administration, Oral; Adolescent; Adult; Anaphylaxis; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprost; Drug Hypersensitivity; Eicosanoids; Female; Humans; Leukotriene E4; Male; Middle Aged; Phenotype; Young Adult	2019
Heterogeneity of lower airway inflammation in patients with NSAID-exacerbated respiratory disease. The Journal of allergy and clinical immunology, 2021, Volume: 147, Issue:4 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Eosinophilia; Eosinophils; Female; Humans; Inflammation; Leukotriene E4; Male; Middle Aged; Nasal Lavage; Neutrophils; Rhinitis; Sinusitis	2021
Effect of TGF-β1 on eosinophils to induce cysteinyl leukotriene E4 production in aspirin-exacerbated respiratory disease. PloS one, 2021, Volume: 16, Issue:8 Topics: Adult; Animals; Aspirin; Asthma, Aspirin-Induced; Eosinophils; Female; Gene Expression Regulation; Glutathione Transferase; Humans; Inflammation; Leukotriene E4; Male; Mice; Middle Aged; p38 Mitogen-Activated Protein Kinases; Receptors, Leukotriene; Respiratory System; Respiratory System Abnormalities; Transforming Growth Factor beta1	2021
Urinary leukotriene E4 is a biomarker for chronic rhinosinusitis associated with leukotriene dysregulation irrespective of aspirin sensitivity status. International forum of allergy & rhinology, 2022, Volume: 12, Issue:5 Topics: Aspirin; Biomarkers; Chronic Disease; Humans; Leukotriene E4; Leukotrienes; Sinusitis	2022
Mediator production and severity of aspirin-induced respiratory reactions: Impact of sampling site and body mass index. The Journal of allergy and clinical immunology, 2022, Volume: 150, Issue:1 Topics: Aspirin; Asthma, Aspirin-Induced; Body Mass Index; Humans; Leukotriene E4; Respiratory System; Sinusitis; Tryptases	2022
Trial of thromboxane receptor inhibition with ifetroban: TP receptors regulate eicosanoid homeostasis in aspirin-exacerbated respiratory disease. The Journal of allergy and clinical immunology, 2023, Volume: 152, Issue:3 Topics: Animals; Aspirin; Asthma, Aspirin-Induced; Dinoprostone; Eicosanoids; Homeostasis; Humans; Leukotriene E4; Mice; Prostaglandins; Receptors, Thromboxane; Sinusitis; Thromboxanes	2023