aspirin has been researched along with leukotriene b4 in 89 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (37.08) | 18.7374 |
| 1990's | 31 (34.83) | 18.2507 |
| 2000's | 17 (19.10) | 29.6817 |
| 2010's | 7 (7.87) | 24.3611 |
| 2020's | 1 (1.12) | 2.80 |
| Authors | Studies |
|---|---|
| Bulbena, O; Gelpí, E; Montserrat, JM; Picado, C; Plaza, V; Prat, J; Ramis, I; Rosellò, J | 1 |
| Asako, H; Granger, DN; Kubes, P; Wallace, J; Wolf, RE | 1 |
| Christiansen, SC; Juergens, UR; Stevenson, DD; Zuraw, BL | 2 |
| Abe, M; Shigematsu, N; Tanaka, K | 1 |
| Grimminger, F; Seeger, W; Sibelius, U | 1 |
| Karvonen, JI; Koskinen, MO; Metsä-Ketelä, TJ; Moilanen, EK; Nieminen, MM; Vapaatalo, H | 1 |
| Hamasaki, Y; Miyazaki, S | 1 |
| Ladnyĭ, AI; Malaia, LT | 1 |
| Borgeat, P; Fournier, M; Hebert, J; Pelletier, G; Salari, H | 1 |
| Agius, RM; Hardy, C; Holgate, ST; Howarth, PH; Robinson, C | 1 |
| Ferreri, NR; Howland, WC; Spiegelberg, HL; Stevenson, DD | 1 |
| Braquet, P; Jancar, S; Lauzière, M; Sirois, P; Thériault, P | 1 |
| Bonta, IL; Elliott, GR; Lauwen, AP | 1 |
| Arm, JP; Lee, TH; O'Hickey, SP; Spur, BW | 1 |
| Jose, PJ; Rampart, M; Williams, TJ | 1 |
| Altomare, GF; Pigatto, PD; Polenghi, MM; Tadini, GL; Villa, S | 1 |
| Docherty, JC; Wilson, TW | 1 |
| Anderson, GP; Fennessy, MR | 1 |
| Guichardant, M; Lagarde, M; Naltachayan-Durbin, S | 1 |
| Gryglewski, RJ; Marcinkiewicz, E; Michalska, Z; Nizankowska, E; Radomski, M; Szczeklik, A; Wandzilak, M | 1 |
| Housholder, GT | 1 |
| Palmer, RM; Salmon, JA | 1 |
| Kaliner, MA; Lundgren, JD; Shelhamer, JH | 1 |
| Abramson, S; Edelson, H; Haines, K; Herman, R; Kimmel, S; Korchak, H; Levin, RI; Ludewig, R; Rider, L; Weissmann, G | 1 |
| Chaud, MA; Gimeno, AL; Gimeno, MF; Viggiano, JM | 1 |
| Schulz, R; Seeger, W | 1 |
| Borgeat, P; Braquet, P; Etienne, A; Sirois, P; Touvay, C; Vilain, B | 1 |
| Marcus, AJ | 1 |
| Parisi, VM; Walsh, SW | 1 |
| Greaves, MW | 1 |
| Canete-Soler, R; Patrignani, P | 1 |
| Colotta, F; de Gaetano, G; Semeraro, N; Villa, S | 1 |
| Fantini, F | 1 |
| Lewis, RA | 1 |
| Newman, JH; Sheller, JR | 1 |
| Moncada, S; Salmon, JA; Simmons, PM | 1 |
| Hunneyball, IM; Mason, CG; Steele, L | 1 |
| Borgeat, P; Picard, S; Roy, S; Sirois, P; Vallerand, P | 1 |
| ten Hoor, F | 1 |
| Bonne, C; Coquelet, C; Lonchampt, MO; Massé, JP; Regnault, F; Sincholle, D | 1 |
| Robinson, DR | 1 |
| Brzozowski, T; Konturek, SJ; Majka, J; Stachura, J | 1 |
| Azevedo, I; Bachelet, M; de Blic, J; Scheinmann, P; Vargaftig, BB | 1 |
| Levi, G; Minghetti, L | 1 |
| Longhurst, JC; Pan, HL; Stahl, GL | 1 |
| Falach-Vaknin, E; Fishman, P; Meroni, PL; Rudniki, C; Shoenfeld, Y; Sredni, B | 1 |
| Arvind, P; Duceman, B; Lovelace, CI; Papavassiliou, ED; Qiao, L; Rigas, B; Tsioulias, GJ | 1 |
| Rola-Pleszczynski, M; Thivierge, M | 1 |
| Anderson, DC; Granger, DN; Kvietys, PR; McIntire, LV; Takemura, T; Wolf, RE; Yoshida, N | 1 |
| Goldman, IS; Levine, L; Rigas, B | 1 |
| Herold, M; Kähler, CM; Reinisch, N; Wiedermann, CJ | 1 |
| Abendroth, D; Mickley, V; Schilling, M; Storck, M; Techt, B | 1 |
| Obata, Y; Oda, M; Yamamoto, N; Yokota, K | 1 |
| Cervar, M; Desoye, G; Kainer, F; Nelson, DM | 1 |
| Ercan, ZS; Firat, S; Gürsel, T | 1 |
| Aghabeigi, B; Haque, M; Harris, M; Henderson, B; Hodges, SJ; Wasil, M | 1 |
| Dalsgaard, CJ; Haegerstrand, A; Martinsson, T | 1 |
| Daugschies, A; Ruttkowski, B | 1 |
| Hippenstiel, S; Jahn, HU; Klockmann, MT; Krämer, HJ; Suttorp, N | 1 |
| Dyavanapalli, M; Frommel, TO; Kazi, N; Liao, Y; Lietz, H; Mobarhan, S; Oldham, T | 1 |
| Clark, JM; Fokin, VV; Levy, BD; Petasis, NA; Serhan, CN; Wakelam, MJ | 1 |
| Lal, AA; Patterson, PS; Xiao, L; Yang, C | 1 |
| Itoh, H; Itoh, S; Iwabuchi, A; Jin, M; Konishi, N; Masamune, O; Odashima, M; Okuyama, A; Otaka, M; Otani, S; Pacheco, I; Tashima, Y; Wada, I; Watanabe, S | 1 |
| Clish, CB; Petasis, NA; Pouliot, M; Serhan, CN; Van Dyke, TE | 1 |
| Engström, K; Saldeen, T; Wallin, R | 1 |
| Devchand, PR; Qiu, FH; Serhan, CN; Wada, K | 1 |
| Antczak, A; Barnes, PJ; Gorski, P; Kharitonov, S; Montuschi, P | 1 |
| Arroyo, V; Clària, J; Gaya, J; López-Parra, M; Planagumà, A; Pueyo, G; Titos, E | 1 |
| Asadullah, K; Bauman, J; Colgan, SP; Fierro, IM; Giesen, C; Guilford, W; Parkinson, JF; Perez, HD; Schottelius, AJ | 1 |
| Barbanti, M; de Lima, OM; Distrutti, E; Fiorucci, S; Mencarelli, A; Morelli, A; Palazzini, E; Romano, M; Wallace, JL | 1 |
| Cirino, G; Distrutti, E; Fiorucci, S; Laufor, SA; Mencarelli, A; Morelli, A; Wallace, JL | 1 |
| Akiyama, K; Higashi, A; Higashi, N; Mita, H; Taniguchi, M | 1 |
| Zailaie, MZ | 1 |
| Cerletti, C; Dell'Elba, G; Evangelista, V; Manarini, S; Rotondo, S | 1 |
| Badovinac, RL; Hosokawa, I; Howell, TH; Karimbux, NY; Kawai, T; Kim, DM; Koszeghy, KL | 1 |
| Aguejouf, O; Belon, P; Desplat, V; Doutremepuich, C; Eizayaga, FX | 1 |
| Azain, MJ; Hargrave-Barnes, KM; Miner, JL | 1 |
| Hassan, AM | 1 |
| Daham, K; Dahlén, B; Dahlén, SE; Delin, I; Gaber, F; Gülich, A; Gyllfors, P; Higashi, A; Higashi, N; James, A; Kumlin, M; Nord, M; Skedinger, M | 1 |
| Blair, IA; Jian, W; Lee, SH; Williams, MV | 1 |
| Basselin, M; Chen, M; Ramadan, E; Rapoport, SI | 1 |
| Chen, W; Cherukuri, MK; Flores-Santana, W; Gorczynski, MJ; King, SB; Mitchell, JB; Moody, T; Shoman, ME; Thetford, A; Velázquez, C; Wink, DA | 1 |
| Aijima, R; Ioi, H; Kido, MA; Murata, N; Oida, H; Ouchi, M; Takao, T; Yamaza, T | 1 |
| Czlonkowski, A; Filipiak, KJ; Janicki, PK; Kaplon-Cieslicka, A; Kondracka, A; Kosior, DA; Opolski, G; Postula, M; Rosiak, M; Trzepla, E; Zaremba, M | 1 |
| Boyce, JA; Cardet, JC; Chhay, H; Cutler, AJ; Feng, C; Kidder, MS; Laidlaw, TM; Liu, T | 1 |
| Yokomizo, T | 1 |
| Borish, L; Pal, K; Payne, SC; Ramsden, M; Shim, YM; Steinke, JW | 1 |
| AlaEddine, M; Authier, H; Bernad, J; Bouschbacher, M; Coste, A; Dardenne, C; Lefèvre, L; Meunier, E; Pipy, B; Salon, M | 1 |
5 review(s) available for aspirin and leukotriene b4
| Article | Year |
|---|---|
The mast cell as a primary effector cell in the pathogenesis of asthma.
Topics: Aspirin; Asthma; Bronchi; Bronchial Provocation Tests; Eosinophils; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Leukotriene B4; Mast Cells; Neutrophils; Pulmonary Alveoli; SRS-A | 1986 |
The role of eicosanoids in respiratory mucus hypersecretion.
Topics: Animals; Arachidonic Acids; Aspirin; Asthma; Bronchial Diseases; Cells, Cultured; Fatty Acids, Unsaturated; Humans; Leukotriene B4; Leukotrienes; Mucoproteins; Mucus; Prostaglandins; Thromboxanes | 1985 |
Transcellular metabolism of eicosanoids.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aspirin; Blood Platelets; Cell Communication; Cell Membrane Permeability; Eicosanoic Acids; Endothelium; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase; Neutrophils; Phospholipases; Prostaglandin-Endoperoxide Synthases; SRS-A | 1986 |
Arachidonic acid metabolites in the healthy and diseased lung.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Asthma; Bronchitis; Dinoprost; Dinoprostone; Epoprostenol; Humans; Leukotriene B4; Lung; Lung Diseases; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostaglandins G; Prostaglandins H; Pulmonary Circulation; Pulmonary Ventilation; SRS-A | 1984 |
Prostaglandins and anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Central Nervous System Diseases; Cyclic AMP; Drug Hypersensitivity; Female; Gastrointestinal Diseases; Glucocorticoids; Hemostasis; Humans; Kidney; Leukotriene B4; Liver; Mice; Nutrition Disorders; Pregnancy; Prostaglandins; Puerperal Disorders; Thrombosis; Thromboxanes | 1983 |
4 trial(s) available for aspirin and leukotriene b4
| Article | Year |
|---|---|
Release of peptide leukotriene into nasal secretions after local instillation of aspirin in aspirin-sensitive asthmatic patients.
Topics: Administration, Intranasal; Adult; Albumins; Aspirin; Asthma; Dinoprost; Dinoprostone; Drug Hypersensitivity; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotrienes; Male; Middle Aged; Nasal Mucosa; Prostaglandin D2 | 1992 |
Influence of systemic cyclooxygenase inhibition with single-dose aspisol on kinetics of arachidonic acid metabolites in the venous effluate of transplanted kidney grafts in humans.
Topics: Adult; Arachidonic Acids; Aspirin; Creatinine; Cyclooxygenase Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Histocompatibility Testing; Humans; Kidney Transplantation; Leukotriene B4; Lysine; Male; Middle Aged; Prostaglandins F; Thromboxane B2 | 1996 |
Effect of low-dose aspirin in combination with stable fish oil on whole blood production of eicosanoids.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Drug Interactions; Eicosanoids; Eicosapentaenoic Acid; Fish Oils; Humans; Leukotriene B4; Middle Aged; Thromboxane B2 | 2001 |
The effect of aspirin on gingival crevicular fluid levels of inflammatory and anti-inflammatory mediators in patients with gingivitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dental Plaque Index; Dinoprostone; Female; Gingival Crevicular Fluid; Gingival Hemorrhage; Gingivitis; Humans; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Leukotriene B4; Lipoxins; Male; Periodontal Pocket; Placebos | 2007 |
80 other study(ies) available for aspirin and leukotriene b4
| Article | Year |
|---|---|
Modulation of leukocyte adhesion in rat mesenteric venules by aspirin and salicylate.
Topics: Animals; Aspirin; Cell Adhesion; Cell Movement; Leukocytes; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Splanchnic Circulation; Venules | 1992 |
Arachidonic acid metabolism in monocytes of aspirin-sensitive asthmatic patients before and after oral aspirin challenge.
Topics: Administration, Oral; Adult; Arachidonic Acid; Aspirin; Asthma; Bronchial Spasm; Calcimycin; Eicosanoids; Female; Humans; Leukotriene B4; Male; Middle Aged; Monocytes; Thromboxane B2 | 1992 |
Effects of a 5-lipoxygenase inhibitor, AA861, on lipoxygenase metabolism and superoxide anion generation by human polymorphonuclear leukocytes--potentiation of superoxide anion generation by LTB4.
Topics: Anions; Arachidonate Lipoxygenases; Arachidonic Acid; Aspirin; Benzoquinones; Complement C5a; Humans; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Superoxides | 1992 |
Amplification of LTB4 generation in AM-PMN cocultures: transcellular 5-lipoxygenase metabolism.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Aspirin; Cell Separation; Cells, Cultured; Cytological Techniques; Eicosanoids; Humans; Leukotriene B4; Macrophages; Neutrophils; Pulmonary Alveoli; Rabbits; Tritium | 1991 |
Platelet-activating factor impairs mucociliary transport and increases plasma leukotriene B4 in man.
Topics: Administration, Inhalation; Adult; Aspirin; Bronchi; Female; Humans; Leukotriene B4; Male; Methacholine Chloride; Middle Aged; Mucociliary Clearance; Platelet Activating Factor; Platelet Aggregation; Respiratory Mechanics | 1991 |
[Role of polymorphonucleocyte-produced leukotriene B4 in Kawasaki disease].
Topics: Aspirin; Female; gamma-Globulins; Humans; Immunization, Passive; Leukotriene B4; Male; Mucocutaneous Lymph Node Syndrome; Neutrophils | 1990 |
[Pathogenetic and therapeutic significance of the angioprotective systems in patients with coronary arteriosclerosis].
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Coronary Artery Disease; Depression, Chemical; Drug Therapy, Combination; Humans; Leukotriene B4; Male; Middle Aged; Quercetin; Stimulation, Chemical; Thromboxane A2 | 1990 |
Studies on the release of leukotrienes and histamine by human lung parenchymal and bronchial fragments upon immunologic and nonimmunologic stimulation. Effects of nordihydroguaiaretic acid, aspirin, and sodium cromoglycate.
Topics: Adjuvants, Immunologic; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Aspirin; Bronchi; Catechols; Cromolyn Sodium; Histamine Release; Humans; Kinetics; Leukotriene B4; Lipoxygenase; Lipoxygenase Inhibitors; Lung; Masoprocol; SRS-A | 1985 |
Release of leukotrienes, prostaglandins, and histamine into nasal secretions of aspirin-sensitive asthmatics during reaction to aspirin.
Topics: Adult; Aspirin; Asthma; Dinoprostone; Drug Hypersensitivity; Female; Forced Expiratory Volume; Histamine Release; Humans; Leukotriene B4; Male; Middle Aged; Nasal Mucosa; Prostaglandins E; Reference Values; SRS-A | 1988 |
Paf-induced release of spasmogens from guinea-pig lungs.
Topics: Animals; Aspirin; Bronchi; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Indoles; Indomethacin; Lactones; Leukotriene B4; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; SRS-A; Trachea | 1989 |
Prostaglandin E2 inhibits and indomethacin and aspirin enhance, A23187-stimulated leukotriene B4 synthesis by rat peritoneal macrophages.
Topics: Animals; Aspirin; Calcimycin; In Vitro Techniques; Indomethacin; Leukotriene B4; Macrophages; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Thromboxane B2 | 1989 |
Airway responsiveness to histamine and leukotriene E4 in subjects with aspirin-induced asthma.
Topics: Adult; Aspirin; Asthma; Bronchial Provocation Tests; Female; Histamine; Humans; Leukotriene B4; Male; Middle Aged; Time Factors | 1989 |
Rabbit leukocytes activated by C5a des Arg and N-formyl-methionyl-leucyl-phenylalanine promote endothelial prostacyclin production. Evidence for a role of hydrogen peroxide.
Topics: Animals; Aspirin; Cell Adhesion; Complement C5a, des-Arginine; Endothelium, Vascular; Epoprostenol; Hydrogen Peroxide; In Vitro Techniques; Leukocytes; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Rabbits | 1989 |
Arachidonic acid and LTB4 enhance aggregation of psoriatic peripheral blood mononuclear leukocytes in vitro.
Topics: Adult; Aged; Arachidonic Acid; Arachidonic Acids; Aspirin; Cell Aggregation; Female; Humans; In Vitro Techniques; Indomethacin; Leukotriene B4; Male; Masoprocol; Middle Aged; Monocytes; Psoriasis | 1987 |
Indomethacin increases the formation of lipoxygenase products in calcium ionophore stimulated human neutrophils.
Topics: Aspirin; Calcimycin; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Kinetics; Leukotriene B4; Lipoxygenase; Neutrophils; SRS-A | 1987 |
Lipoxygenase metabolites mediate increased airways responsiveness to histamine after acute platelet activating factor exposure in the guinea-pig.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Airway Resistance; Animals; Aspirin; Bronchi; Chromones; Female; Guinea Pigs; Histamine; Leukotriene B4; Lipoxygenase; Lung Compliance; Male; Platelet Activating Factor; Pyrazoles; Quinolinium Compounds; SRS-A | 1988 |
Occurrence of the 15-hydroxy derivative of dihomogammalinolenic acid in human platelets and its biological effect.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Aspirin; Blood Platelets; Drug Synergism; Fatty Acids, Unsaturated; Humans; Hydroxylation; Kinetics; Leukotriene B4; Linolenic Acids; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic | 1988 |
An abnormality of arachidonic acid metabolism is not a generalized phenomenon in patients with aspirin-induced asthma.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adult; Arachidonate 12-Lipoxygenase; Arachidonic Acids; Aspirin; Asthma; Blood Platelets; Female; Humans; Hydroxyeicosatetraenoic Acids; Leukocytes; Leukotriene B4; Male; Middle Aged | 1988 |
Intolerance to aspirin and the nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Drug Hypersensitivity; Drug Tolerance; Humans; Hydroxyeicosatetraenoic Acids; Leukocytes; Leukotriene B4; Leukotrienes; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; SRS-A | 1985 |
Comparison of the effects of some compounds on human neutrophil degranulation and leukotriene B4 and thromboxane B2 synthesis.
Topics: Arachidonic Acids; Aspirin; Calcimycin; Humans; In Vitro Techniques; Indomethacin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenylbutazone; Thromboxane B2; Thromboxanes | 1985 |
Modes of action of aspirin-like drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Calcium; Cell Aggregation; Complement C5; Cyclic AMP; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Lymphocyte Activation; Neutrophils; Piroxicam; Prostaglandin Antagonists; Salicylates; Superoxides; Thiazines; Thromboxane A2 | 1985 |
On the inotropic effects of leukotrienes in the isolated urinary bladder of guinea pigs and rats.
Topics: Animals; Aspirin; Catechols; Guinea Pigs; In Vitro Techniques; Leukotriene B4; Male; Masoprocol; Muscle Contraction; Rats; Rats, Inbred Strains; SRS-A; Urinary Bladder | 1985 |
Release of leukotrienes into the perfusate of calcium-ionophore stimulated rabbit lungs. Influence of 5-lipoxygenase inhibitors.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate Lipoxygenases; Aspirin; Benzoquinones; Blood Pressure; Calcimycin; Dose-Response Relationship, Drug; Epoprostenol; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Perfusion; Pulmonary Artery; Quinones; Rabbits; Secretory Rate; SRS-A | 1986 |
Characterization of platelet activating factor (PAF)-acether-induced contractions of guinea-pig lung strips by selected inhibitors of arachidonic acid metabolism and by PAF-acether antagonists.
Topics: Animals; Aspirin; Benzofurans; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; Imidazoles; Lactones; Leukotriene B4; Lignans; Lung; Male; Methacrylates; Muscle Contraction; Muscle, Smooth; Plant Extracts; Platelet Activating Factor; Prostaglandin Antagonists; Pyrilamine; SRS-A | 1986 |
The role of arachidonic acid metabolites in preeclampsia.
Topics: Arachidonic Acids; Aspirin; Blood Platelets; Epoprostenol; Female; Hemodynamics; Humans; Leukotriene B4; Lipoxygenase; Maternal-Fetal Exchange; Pre-Eclampsia; Pregnancy; Prostaglandins E; Prostaglandins F; Thromboxanes; Trophoblasts | 1986 |
Pharmacology and significance of nonsteroidal anti-inflammatory drugs in the treatment of skin diseases.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Dermatitis; Eicosanoic Acids; Humans; Ibuprofen; Leukotriene B4; Lipoxygenase Inhibitors; Propionates; Prostaglandins; Skin; Skin Diseases | 1987 |
Biosynthesis, characterization and inhibition of leukotriene B4 in human whole blood.
Topics: Aspirin; Calcimycin; Chromatography, Thin Layer; Cross Reactions; Fibrinolytic Agents; Humans; Immune Sera; Kinetics; Leukotriene B4; Pyrazoles; Pyrazolones; Radioimmunoassay | 1987 |
Arachidonic acid and leukotriene B4 induce aggregation of human peripheral blood mononuclear leucocytes in vitro.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 8,11,14-Eicosatrienoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Catechols; Cell Aggregation; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Indomethacin; Leukocytes; Leukotriene B4; Masoprocol; Neutrophils; Pyrazoles | 1984 |
[Recent discoveries in the field of mediators of anti-inflammation: leukotrienes].
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arachidonic Acids; Aspirin; Humans; Indomethacin; Inflammation; Leukotriene B4; Muscle, Smooth; Oxidation-Reduction; SRS-A | 1984 |
How are prostaglandins and leukotrienes involved in immunological alterations?
Topics: Animals; Arachidonic Acids; Aspirin; Burns; Cell Membrane Permeability; Dinoprostone; Eosinophils; Free Radicals; Humans; Inflammation; Leukotriene B4; Neutrophils; Prostaglandins; Prostaglandins E; Receptors, Immunologic; Receptors, Leukotriene B4; Skin; SRS-A; Steroids; Thromboxane-A Synthase | 1984 |
The effects of BW755C and other anti-inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally-induced acute inflammation.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Aspirin; Cell Movement; Dexamethasone; Dinoprostone; Exudates and Transudates; Fatty Acids, Unsaturated; Indomethacin; Inflammation; Leukocyte Count; Leukocytes; Leukotriene B4; Male; Prostaglandins E; Pyrazoles; Rats; Thromboxane B2 | 1983 |
Contribution of LTB4 to leukocyte migration in inflammatory lesions.
Topics: Aspirin; Cell Movement; Humans; In Vitro Techniques; Inflammation; Leukocytes; Leukotriene B4 | 1984 |
Evidence for a mediator role of thromboxane A2 in the myotropic action of leukotriene B4 (LTB4) on the guinea-pig lung.
Topics: Animals; Arachidonic Acids; Aspirin; Female; Flufenamic Acid; Guinea Pigs; Imidazoles; Indoles; Leukotriene B4; Leukotrienes; Lipid Peroxides; Lung; Male; Muscle Contraction; Peroxides; Prostaglandins; Pyridines; Quinacrine; Thromboxane A2; Thromboxane B2; Thromboxanes | 1982 |
[The Nobel Prize for Medicine 1982. On essential fatty acids, prostaglandins and acetylsalicylic acid].
Topics: Aspirin; Humans; Leukotriene B4; Prostaglandin Antagonists; Prostaglandins; Thromboxanes | 1983 |
Evidence of leukotriene B4 biosynthesis in epithelial lens cells.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acids; Aspirin; Catechols; Cattle; Cells, Cultured; Cyclooxygenase Inhibitors; Epithelium; Lens Capsule, Crystalline; Lens, Crystalline; Leukotriene B4; Lipoxygenase Inhibitors; Masoprocol | 1983 |
Role of neutrophils and mucosal blood flow in gastric adaptation to aspirin.
Topics: Adaptation, Physiological; Administration, Oral; Amino Acid Oxidoreductases; Animals; Arginine; Aspirin; Capsaicin; Denervation; Female; Gastric Acid; Gastric Mucosa; Leukotriene B4; Neurons, Afferent; Neutrophils; Nitric Oxide Synthase; Nitroarginine; Prostaglandins; Rats; Rats, Wistar; Regional Blood Flow | 1994 |
Enhanced arachidonic acid metabolism in alveolar macrophages from wheezy infants. Modulation by dexamethasone.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Calcimycin; Case-Control Studies; Dexamethasone; Dose-Response Relationship, Drug; Female; Glucocorticoids; Humans; In Vitro Techniques; Infant; Ionophores; Leukotriene B4; Lysine; Macrophages, Alveolar; Male; Respiratory Sounds; Thromboxane A2 | 1995 |
Induction of prostanoid biosynthesis by bacterial lipopolysaccharide and isoproterenol in rat microglial cultures.
Topics: Animals; Arachidonic Acid; Aspirin; Astrocytes; Cells, Cultured; Dose-Response Relationship, Drug; Isoproterenol; Leukotriene B4; Lipopolysaccharides; Microglia; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Time Factors | 1995 |
Differential effect of 5- and 15-lipoxygenase products on ischemically sensitive abdominal visceral afferents.
Topics: Abdomen; Animals; Aspirin; Cats; Electrophysiology; Ischemia; Leukotriene B4; Lipoxygenase; Naphthaleneacetic Acids; Neurons, Afferent; Quinolines; Viscera | 1995 |
Inhibition of monocyte leukotriene B4 production after aspirin desensitization.
Topics: Adult; Aspirin; Asthma; Desensitization, Immunologic; Female; Humans; Leukotriene B4; Leukotriene C4; Male; Middle Aged; Monocytes; Thromboxane B2 | 1995 |
Aspirin modulates interleukin-3 production: additional explanation for the preventive effects of aspirin in antiphospholipid antibody syndrome.
Topics: Animals; Antiphospholipid Syndrome; Aspirin; Cells, Cultured; Dose-Response Relationship, Drug; Interleukin-3; Leukotriene B4; Leukotriene C4; Macrophages; Mice; Mice, Inbred ICR; Osmolar Concentration; Spleen | 1995 |
Prostaglandin E2 down-regulates the expression of HLA-DR antigen in human colon adenocarcinoma cell lines.
Topics: Adenocarcinoma; Aspirin; Base Sequence; Cell Line; Colonic Neoplasms; Dinoprost; Dinoprostone; DNA Primers; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; HLA-DR Antigens; Humans; Leukotriene B4; Molecular Sequence Data; Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 1995 |
Involvement of both cyclooxygenase and lipoxygenase pathways in platelet-activating factor-induced interleukin-6 production by alveolar macrophages.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Arachidonate 5-Lipoxygenase; Aspirin; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Ibuprofen; Indomethacin; Interleukin-6; Leukotriene B4; Macrophages, Alveolar; Male; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 1994 |
Molecular determinants of aspirin-induced neutrophil adherence to endothelial cells.
Topics: Adult; Antibodies, Monoclonal; Antigens, CD; Aspirin; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Flow Cytometry; Fluorescent Antibody Technique; Humans; Infant, Newborn; Intercellular Adhesion Molecule-1; Leukotriene B4; Neutrophils; Platelet Activating Factor; Umbilical Veins | 1993 |
Altered eicosanoid levels in human colon cancer.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Colonic Neoplasms; Dinoprostone; Eicosanoids; Epoprostenol; Female; Humans; Intestinal Mucosa; Leukotriene B4; Male; Middle Aged; Thromboxane A2; Time Factors | 1993 |
Interaction of substance P with epidermal growth factor and fibroblast growth factor in cyclooxygenase-dependent proliferation of human skin fibroblasts.
Topics: Animals; Arachidonic Acid; Aspirin; Cattle; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Epidermal Growth Factor; Fibroblast Growth Factors; Fibroblasts; Humans; Leukotriene B4; Prostaglandin-Endoperoxide Synthases; Skin; Substance P | 1996 |
Inhibitory effects of the new anti-platelet agent KBT-3022 and its metabolite on rabbit neutrophil function in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Calcium; Cell Adhesion; Cilostazol; Complement C3-C5 Convertases; Complement C5a; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Thiazoles; Ticlopidine | 1996 |
Drug actions in preeclampsia: aspirin, but not magnesium chloride or dihydralazine, differentially inhibits cultured human trophoblast release of thromboxane and prostacyclin without affecting angiotensin II, endothelin-1, or leukotriene B4 secretion.
Topics: Angiotensin II; Antihypertensive Agents; Aspirin; Cells, Cultured; Cyclooxygenase Inhibitors; Dihydralazine; Endothelin-1; Epoprostenol; Female; Humans; Leukotriene B4; Magnesium Chloride; Pre-Eclampsia; Pregnancy; Thromboxane B2; Trophoblasts | 1997 |
Increased serum leukotriene B4 level in the active stage of rheumatoid arthritis in children.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Case-Control Studies; Child; Child, Preschool; Cyclooxygenase Inhibitors; Female; Hemoglobins; Humans; Indomethacin; Leukocyte Count; Leukotriene B4; Lipoxygenase Inhibitors; Male; Prednisolone | 1997 |
The role of oxygen free radicals in idiopathic facial pain.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Chronic Disease; Cytokines; Dinoprostone; Facial Pain; Female; Free Radicals; Gentisates; Humans; Hydroxybenzoates; Hydroxyeicosatetraenoic Acids; Iron Chelating Agents; Leukotriene B4; Male; Mastication; Middle Aged; Reactive Oxygen Species; Synovial Fluid; Temporomandibular Joint; Temporomandibular Joint Dysfunction Syndrome; Thiobarbituric Acid Reactive Substances | 1997 |
Effects of ropivacaine on eicosanoid release from human granulocytes and endothelial cells in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Amides; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Eicosanoids; Endothelium, Vascular; Granulocytes; Humans; Hydrocortisone; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lidocaine; Mesalamine; Ropivacaine; Thrombin; Zymosan | 1997 |
Modulation of migration of Oesophagostomum dentatum larvae by inhibitors and products of eicosanoid metabolism.
Topics: Animals; Aspirin; Biological Assay; Cyclooxygenase Inhibitors; Diethylcarbamazine; Dose-Response Relationship, Drug; Eicosanoids; Indomethacin; Larva; Leukotriene B4; Leukotriene C4; Leukotriene D4; Leukotrienes; Lipoxygenase Inhibitors; Locomotion; Oesophagostomum; Prostaglandins; Swine | 1998 |
Interaction of human neutrophils with airway epithelial cells: reduction of leukotriene B4 generation by epithelial cell derived prostaglandin E2.
Topics: Animals; Aspirin; Bronchi; Cell Communication; Cells, Cultured; Coculture Techniques; Dinoprostone; Epithelial Cells; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotrienes; Neutrophils; Superoxides; Swine; Trachea | 1998 |
Effect of aspirin on prostaglandin E2 and leukotriene B4 production in human colonic mucosa from cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Arachidonic Acid; Aspirin; Colon; Colonic Neoplasms; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; Intestinal Mucosa; Leukotriene B4; Lipoxygenase; Male; Middle Aged | 1997 |
Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a 'stop' signaling switch for aspirin-triggered lipoxin A4.
Topics: Aspirin; Brassica; Enzyme Inhibitors; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kinetics; Leukotriene B4; Lipoxins; Neutrophils; Phospholipase D; Polyisoprenyl Phosphates; Recombinant Proteins; Signal Transduction; Stereoisomerism; Superoxides | 1999 |
Role of eicosanoids in the pathogenesis of murine cerebral malaria.
Topics: Animals; Aspirin; Brain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Isoenzymes; Leukotriene B4; Leukotrienes; Lipoxygenase; Malaria, Cerebral; Membrane Proteins; Mice; Mice, Inbred ICR; Parasitemia; Phospholipases A; Phospholipases A2; Plasmodium berghei; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Reverse Transcriptase Polymerase Chain Reaction; Spleen | 1999 |
Association of 72-kDa heat shock protein expression with adaptation to aspirin in rat gastric mucosa.
Topics: Adaptation, Physiological; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Gastric Mucosa; Gene Expression; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Immunoenzyme Techniques; Leukotriene B4; Long-Term Care; Male; Rats; Rats, Sprague-Dawley | 1999 |
Lipoxin A(4) analogues inhibit leukocyte recruitment to Porphyromonas gingivalis: a role for cyclooxygenase-2 and lipoxins in periodontal disease.
Topics: Aggressive Periodontitis; Animals; Aspirin; Bacteroidaceae Infections; Bronchoalveolar Lavage Fluid; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Gingival Crevicular Fluid; Humans; Hydroxyeicosatetraenoic Acids; Isoenzymes; Leukotriene B4; Lipoxins; Lung; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Myocardium; Neutrophil Infiltration; Neutrophils; Porphyromonas gingivalis; Prostaglandin-Endoperoxide Synthases; RNA, Messenger | 2000 |
Aspirin-triggered lipoxin A4 and lipoxin A4 up-regulate transcriptional corepressor NAB1 in human neutrophils.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; DNA, Complementary; Gene Expression Regulation; GTP-Binding Proteins; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxins; Models, Biological; Neutrophils; Receptors, Cell Surface; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transcription, Genetic; Up-Regulation | 2001 |
Increased exhaled cysteinyl-leukotrienes and 8-isoprostane in aspirin-induced asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Breath Tests; Cysteine; Dinoprost; Dinoprostone; F2-Isoprostanes; Female; Humans; Inflammation Mediators; Leukotriene B4; Leukotrienes; Male; Middle Aged; Oxidative Stress; Oxytocics; Respiratory System; Vasoconstrictor Agents | 2002 |
Aspirin (ASA) regulates 5-lipoxygenase activity and peroxisome proliferator-activated receptor alpha-mediated CINC-1 release in rat liver cells: novel actions of lipoxin A4 (LXA4) and ASA-triggered 15-epi-LXA4.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Aspirin; Chemokine CXCL1; Chemokines; Chemokines, CXC; Chemotactic Factors; Dinoprostone; Hepatocytes; Hydroxyeicosatetraenoic Acids; Intercellular Signaling Peptides and Proteins; Kupffer Cells; Leukotriene B4; Lipoxins; Liver; Models, Biological; Rats; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2002 |
An aspirin-triggered lipoxin A4 stable analog displays a unique topical anti-inflammatory profile.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcimycin; Cell Movement; Chemotaxis, Leukocyte; Croton Oil; Disease Models, Animal; Diterpenes; Female; Guinea Pigs; Humans; Hydroxyeicosatetraenoic Acids; Hypersensitivity, Delayed; Iloprost; Inflammation; Leukotriene B4; Lipoxins; Mice; Phthalic Anhydrides; Skin; Terpenes | 2002 |
Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin.
Topics: Acetates; Acetylation; Adaptation, Physiological; Animals; Arachidonate 5-Lipoxygenase; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gastric Mucosa; Hydroxyeicosatetraenoic Acids; Isoenzymes; Leukotriene B4; Lipoxins; Lipoxygenase Inhibitors; Models, Biological; Prostaglandin-Endoperoxide Synthases; Pyrroles; Rats | 2003 |
Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin.
Topics: Acetates; Acetylation; Adhesiveness; Arachidonate 5-Lipoxygenase; Aspirin; CD11a Antigen; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; E-Selectin; Eicosanoids; Endothelial Cells; Endothelium, Vascular; Fatty Alcohols; Glycols; Humans; Isoenzymes; Leukocytes; Leukotriene B4; Lipopolysaccharides; Lipoxins; Lipoxygenase; Membrane Proteins; Neutrophils; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Pyrans; Pyrroles; Quinolines; Quinolones; Umbilical Cord; Up-Regulation | 2003 |
Increase in urinary leukotriene B4 glucuronide concentration in patients with aspirin-intolerant asthma after intravenous aspirin challenge.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Case-Control Studies; Female; Glucuronides; Humans; Leukotriene B4; Leukotriene E4; Male; Middle Aged; Statistics, Nonparametric | 2004 |
The effect of acetylsalicylic acid on the release rates of leukotrienes B4 and C4 from cultured skin melanocytes of active vitiligo.
Topics: Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Cells, Cultured; Dose-Response Relationship, Drug; Female; Humans; Inflammation Mediators; Leukotriene B4; Leukotriene C4; Male; Melanocytes; Middle Aged; Probability; Reference Values; Sensitivity and Specificity; Vitiligo | 2004 |
The lipoxygenase-cyclooxygenase inhibitor licofelone prevents thromboxane A2-mediated cardiovascular derangement triggered by the inflammatory peptide fMLP in the rabbit.
Topics: Acetates; Animals; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Electrocardiography; Heart Rate; Inflammation; Lactones; Leukotriene B4; Lipoxygenase Inhibitors; Male; Myocardial Ischemia; N-Formylmethionine Leucyl-Phenylalanine; Pyrroles; Rabbits; Sulfones; Thromboxane A2; Time Factors | 2006 |
Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Portal; Lasers; Leukotriene B4; Male; Nitrobenzenes; Platelet Activation; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Thrombosis; Thromboxane B2 | 2007 |
Conjugated linoleic acid-induced fat loss dependence on Delta6-desaturase or cyclooxygenase.
Topics: Adipose Tissue; Adiposity; Animals; Aspirin; Cyclooxygenase Inhibitors; Dietary Fats; Dinoprostone; Eating; Enzyme Inhibitors; Leukotriene B4; Linoleic Acids, Conjugated; Linoleoyl-CoA Desaturase; Lipoxygenase; Lipoxygenase Inhibitors; Liver; Male; Masoprocol; Mice; Piperazines; Prostaglandin-Endoperoxide Synthases; Time Factors; Weight Gain | 2008 |
Selenium status in patients with aspirin-induced asthma.
Topics: Adult; Aged; Antioxidants; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Aspirin; Asthma; Female; Free Radicals; Humans; Leukotriene B4; Leukotrienes; Macrophages; Male; Middle Aged; Selenium | 2008 |
Increased levels of cysteinyl-leukotrienes in saliva, induced sputum, urine and blood from patients with aspirin-intolerant asthma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Biomarkers; Cysteine; Dinoprost; Drug Hypersensitivity; Female; Humans; Leukotriene B4; Leukotrienes; Male; Middle Aged; Saliva; Sputum; Uteroglobin | 2008 |
5-Lipoxygenase-mediated endogenous DNA damage.
Topics: 5-Lipoxygenase-Activating Proteins; Arachidonate 5-Lipoxygenase; Aspirin; Calcimycin; Carrier Proteins; Cell Line; Cyclooxygenase 1; DNA Adducts; DNA Damage; Humans; Hydroxyeicosatetraenoic Acids; Ionophores; Leukotriene B4; Lipid Peroxidation; Lymphocytes; Membrane Proteins; Models, Biological; Prostaglandins | 2009 |
Anti-inflammatory effects of chronic aspirin on brain arachidonic acid metabolites.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Brain; Dinoprostone; Humans; Leukotriene B4; Lipopolysaccharides; Lipoxins; Male; Rats; Rats, Inbred F344; Thromboxane B2 | 2011 |
Nitroxide derivatives of non-steroidal anti-inflammatory drugs exert anti-inflammatory and superoxide dismutase scavenging properties in A459 cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Carrageenan; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclic N-Oxides; Dinoprostone; Disease Models, Animal; Edema; Female; Humans; Indomethacin; Leukotriene B4; Mice; Mice, Nude; Rats; Stomach Ulcer; Superoxide Dismutase | 2012 |
Effect of allergen sensitization on external root resorption.
Topics: Allergens; Alveolar Process; Animals; Arachidonate 5-Lipoxygenase; Aspirin; Biomechanical Phenomena; Bone Resorption; Cyclooxygenase Inhibitors; Epoxide Hydrolases; Iatrogenic Disease; Immunization; Immunoglobulin E; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Leukotriene B4; Leukotrienes; Orthodontic Wires; Ovalbumin; Periodontium; RANK Ligand; Rats; Rats, Inbred BN; Root Resorption; Tooth Movement Techniques; Tumor Necrosis Factor-alpha; Up-Regulation | 2013 |
Lack of effect of common single nucleotide polymorphisms in leukotriene pathway genes on platelet reactivity in patients with diabetes.
Topics: 5-Lipoxygenase-Activating Proteins; Aged; Alleles; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Aspirin; Blood Platelets; Cohort Studies; Diabetes Mellitus, Type 2; Epoxide Hydrolases; Female; Gene Frequency; Genotype; Glutathione Transferase; Humans; Leukotriene B4; Leukotriene E4; Male; Middle Aged; Polymorphism, Single Nucleotide | 2013 |
Prostaglandin E2 resistance in granulocytes from patients with aspirin-exacerbated respiratory disease.
Topics: Adult; Aged; Aspirin; Blood Platelets; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Female; Granulocytes; Humans; Leukotriene B4; Leukotrienes; Male; Middle Aged; Neutrophils; Receptors, Prostaglandin E, EP2 Subtype; Respiratory Tract Diseases; Young Adult | 2014 |
Two distinct leukotriene B4 receptors, BLT1 and BLT2.
Topics: Animals; Aspirin; CD8-Positive T-Lymphocytes; Cell Movement; Cloning, Molecular; Humans; Immunity, Innate; Inflammation; Leukotriene B4; Mice; Receptors, Leukotriene B4; Wound Healing | 2015 |
Suppression of aspirin-mediated eosinophil activation by prostaglandin E
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Cysteine; Dinoprostone; Drug Hypersensitivity; Eosinophils; Humans; Ketorolac; Leukotriene B4; Leukotrienes; Lysine; Sodium Salicylate | 2019 |
Topical Aspirin Administration Improves Cutaneous Wound Healing in Diabetic Mice Through a Phenotypic Switch of Wound Macrophages Toward an Anti-inflammatory and Proresolutive Profile Characterized by LXA4 Release.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Diabetes Mellitus, Experimental; Inflammation; Leukotriene A4; Leukotriene B4; Lipoxins; Macrophages; Mice; Phenotype; Skin; Wound Healing | 2022 |