aspirin and lansoprazole

aspirin has been researched along with lansoprazole in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (5.77)18.2507
2000's23 (44.23)29.6817
2010's22 (42.31)24.3611
2020's4 (7.69)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bergmann, JF; Caulin, C; Chassany, O; Lemaire, M; Segrestaa, JM; Simoneau, G1
Fuchs, W; Müller, P; Simon, B1
Bertaccini, G; Coppelli, G; Coruzzi, G; Frati, P1
Lanas, AI1
Boknik, P; Domschke, W; Fischer, H; Huber, V; Konturek, JW; Luess, H; Neumann, J; Schmitz, W1
Astudillo, L; Rodriguez, JA; Schmeda-Hirschmann, G1
Chan, AO; Chu, KM; Hu, WH; Hui, WM; Lai, CL; Lai, KC; Lam, SK; Lau, GK; Wong, BC; Wong, J; Wong, WM; Yuen, MF1
Harris, AW; Maiden, LP1
Guda, N; Vakil, N1
Nelson, DB; Sawhney, MS1
D'Ambrosio, LP; Franceschi, M; Leandro, G; Longoa, MG; Orsitto, G; Perri, FC; Pilotto, A; Scarcelli, C1
Amer, F; Christopoulos, NG; Goldstein, JL; Huang, B1
Arkkila, PE; Färkkilä, M; Kosunen, TU; Mäkinen, J; Rautelin, H; Seppälä, K; Sipponen, P1
Chiou, CF; Ofman, JJ; Spiegel, BM1
Hull, R; Marshall, RW; Marshall, VJ1
Agustí-Escasany, A; Vallano-Ferraz, A1
Amer, F; Cryer, B; Goldstein, JL; Hunt, B1
Adamopoulos, AB; Anastasakou, E; Anastasopoulou, I; Karafoulidou, A; Kotsi, P; Nasothimiou, EG; Sakizlis, GN; Stergiou, GS1
Bretagne, JF1
Broderick, J; Collins, R; Coughlan, T; Lonergan, MT; O'Neill, D1
Furuta, T; Hishida, A; Ikuma, M; Kodaira, C; Nishino, M; Shirai, N; Sugimoto, M; Sugimura, H; Tanaka, T; Uotani, T; Yamade, M1
Kato, M; Nema, H1
Malmioja, K; Peura, L; Rautio, J1
Abe, S; Ashida, K; Chiba, T; Hiramatsu, N; Itabashi, T; Kanto, T; Matsui, S; Matsumoto, Y; Mizokami, Y; Sakaki, N; Shimada, K; Sugano, K; Uchiyama, S; Uemura, N1
Demir, M; Erbayrak, M; Gokturk, HS; Sakalli, M; Unler, GK; Yilmaz, U1
Furuta, T; Ikuma, M; Kodaira, C; Nishino, M; Sugimoto, M; Uotani, T; Yamade, M1
Ashida, K; Chiba, T; Hiramatsu, N; Kanto, T; Matsui, S; Mizokami, Y; Sakaki, N; Sugano, K; Uemura, N1
Kadota, J; Murakami, K; Tamura, A1
Hedger, NA; Veettil, RP; Woolley, AK1
Andersson, T; Galbraith, H; Nagy, P; Niazi, M; Nylander, S; Ranjan, S; Wallentin, L1
Abtan, J; Anzaha, G; Barthélémy, O; Beygui, F; Brugier, D; Cayla, G; Charland, SL; Collet, JP; Galier, S; Gallois, V; Hulot, JS; Kerneis, M; Montalescot, G; O'Connor, SA; Silvain, J; Stanek, EJ1
Ashida, K; Funao, N; Kawai, T; Matsumoto, Y; Mizokami, Y; Nishimura, A; Oda, K; Sugano, K1
Amant, F; Aspeslagh, S; De Caluwé, A; De Jaeghere, E; Denys, H; Dirix, P; Lippens, L; Naert, E; Tuyaerts, S; Van Dam, PA; Van Nuffel, AMT; Vandecasteele, K; Vuylsteke, P1
Higashi, T; Inoue, R; Mitsutake, T; Morinaga, Y; Nii, K1
Di Leo, A; Leandro, G; Losurdo, G1
Deguchi, H; Fernandez, J; Igarashi, A; Ishii, M; Kawai, T; Suzuki, M; Tsujita, K1
Hirata, A; Hosomi, K; Jouta, M; Kawasaki, N; Nakamura, T; Ogata, F; Ozaki, Y; Tanei, S; Yamashiro, K; Yokoyama, S1
Ladjouzi, N; Romdhani, A; Schlatter, J; Zouloumis, G1

Reviews

4 review(s) available for aspirin and lansoprazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Minimizing complications from nonsteroidal antiinflammatory drugs: cost-effectiveness of competing strategies in varying risk groups.
    Arthritis and rheumatism, 2005, Apr-15, Volume: 53, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Celecoxib; Cost-Benefit Analysis; Drug Therapy, Combination; Gastrointestinal Diseases; Humans; Lactones; Lansoprazole; Naproxen; Omeprazole; Proton Pump Inhibitors; Pyrazoles; Rheumatology; Sulfonamides; Sulfones

2005
[Prevention of GI bleeding due to antiplatelet agents: a labyrinth!].
    Presse medicale (Paris, France : 1983), 2009, Volume: 38, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aspirin; Clopidogrel; Drug Interactions; Drug Therapy, Combination; Gastrointestinal Hemorrhage; Humans; Lansoprazole; Omeprazole; Pantoprazole; Platelet Aggregation; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Ticlopidine

2009
[Prodrug technology in the development of medicinal agents].
    Duodecim; laaketieteellinen aikakauskirja, 2011, Volume: 127, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aspirin; Clopidogrel; Drug Delivery Systems; Drug Design; Humans; Lansoprazole; Oseltamivir; Prodrugs; Simvastatin; Ticlopidine

2011

Trials

18 trial(s) available for aspirin and lansoprazole

ArticleYear
Protection against aspirin-induced gastric lesions by lansoprazole: simultaneous evaluation of functional and morphologic responses.
    Clinical pharmacology and therapeutics, 1992, Volume: 52, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Analysis of Variance; Anti-Ulcer Agents; Aspirin; Double-Blind Method; Female; Gastric Mucosa; Gastroscopy; Humans; Lansoprazole; Male; Membrane Potentials; Omeprazole; Reference Values; Stomach Ulcer

1992
[Studies on the protective effect of lansoprazole on human gastric mucosa against low-dose acetylsalicylic acid. An endoscopic controlled double-blind study].
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Aspirin; Double-Blind Method; Duodenoscopy; Gastroscopy; Histamine H2 Antagonists; Humans; Lansoprazole; Omeprazole; Peptic Ulcer; Platelet Aggregation Inhibitors; Ranitidine

1997
Effect of Helicobacter pylori eradication on cyclooxygenase 2 (COX-2) and inducible nitric oxide synthase (iNOS) expression during gastric adaptation to aspirin (ASA) in humans.
    Microscopy research and technique, 2001, Jun-01, Volume: 53, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Clarithromycin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Electrophoresis, Polyacrylamide Gel; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Immunohistochemistry; Isoenzymes; Lansoprazole; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Omeprazole; Prostaglandin-Endoperoxide Synthases

2001
Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use.
    The New England journal of medicine, 2002, Jun-27, Volume: 346, Issue:26

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Enzyme Inhibitors; Female; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Peptic Ulcer; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proportional Hazards Models; Prospective Studies; Proton Pump Inhibitors; Recurrence; Statistics, Nonparametric

2002
Helicobacter pylori infection and the prevention of peptic ulcer with proton pump inhibitors in elderly subjects taking low-dose aspirin.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2004, Volume: 36, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzimidazoles; Dose-Response Relationship, Drug; Endoscopes, Gastrointestinal; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Omeprazole; Pantoprazole; Peptic Ulcer; Prospective Studies; Proton Pump Inhibitors; Sulfoxides

2004
Ulcer recurrence in high-risk patients receiving nonsteroidalanti-inflammatory drugs plus low-dose aspirin: results of a post HOC subanalysis.
    Clinical therapeutics, 2004, Volume: 26, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Duodenal Ulcer; Female; Humans; Lansoprazole; Male; Middle Aged; Misoprostol; Omeprazole; Peptic Ulcer Hemorrhage; Prospective Studies; Proton Pump Inhibitors; Risk Factors; Secondary Prevention; Stomach Ulcer; Treatment Outcome

2004
Helicobacter pylori eradication as the sole treatment for gastric and duodenal ulcers.
    European journal of gastroenterology & hepatology, 2005, Volume: 17, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Drug Therapy, Combination; Duodenal Ulcer; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Prospective Studies; Proton Pump Inhibitors; Recurrence; Stomach Ulcer; Treatment Outcome

2005
Celecoxib plus aspirin versus naproxen and lansoprazole plus aspirin: a randomized, double-blind, endoscopic trial.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2007, Volume: 5, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Celecoxib; Confidence Intervals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Duodenal Ulcer; Endoscopy, Gastrointestinal; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Incidence; Lansoprazole; Male; Middle Aged; Naproxen; Osteoarthritis; Proton Pump Inhibitors; Pyrazoles; Retrospective Studies; Risk Factors; Stomach Ulcer; Sulfonamides; United States

2007
Do proton pump inhibitors attenuate the effect of aspirin on platelet aggregation? A randomized crossover study.
    Journal of cardiovascular pharmacology, 2009, Volume: 54, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases; Cross-Over Studies; Drug Interactions; Female; Humans; Hypertension; Lansoprazole; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Proton Pump Inhibitors

2009
Preventive effects of lansoprazole and famotidine on gastric mucosal injury induced by low-dose aspirin in Helicobacter pylori-negative healthy volunteers.
    Journal of clinical pharmacology, 2011, Volume: 51, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Aspirin; Cross-Over Studies; Cytochrome P-450 CYP2C19; Famotidine; Female; Gastric Acidity Determination; Gastric Mucosa; Genotype; Histamine H2 Antagonists; Humans; Japan; Lansoprazole; Male; Proton Pump Inhibitors; Severity of Illness Index; Stomach Ulcer; Young Adult

2011
Comparative study of therapeutic effects of PPI and H2RA on ulcers during continuous aspirin therapy.
    World journal of gastroenterology, 2010, Nov-14, Volume: 16, Issue:42

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Drug Therapy, Combination; Endoscopy; Famotidine; Histamine H2 Antagonists; Humans; Lansoprazole; Male; Middle Aged; Peptic Ulcer; Prospective Studies; Proton Pump Inhibitors; Ranitidine; Treatment Outcome; Wound Healing

2010
Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term low-dose aspirin therapy: results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial.
    Journal of gastroenterology, 2011, Volume: 46, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Ulcer Agents; Aspirin; Double-Blind Method; Duodenal Ulcer; Female; Follow-Up Studies; Gefarnate; Humans; Incidence; Japan; Kaplan-Meier Estimate; Lansoprazole; Male; Middle Aged; Platelet Aggregation Inhibitors; Prospective Studies; Secondary Prevention; Stomach Ulcer

2011
Impact of acid inhibition on esophageal mucosal injury induced by low-dose aspirin.
    Digestion, 2012, Volume: 85, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aspirin; Cross-Over Studies; Esophagus; Famotidine; Female; Gastric Acid; Gastric Acidity Determination; Gastroesophageal Reflux; Gastroscopy; Humans; Lansoprazole; Male; Mucous Membrane; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Rabeprazole; Treatment Outcome; Young Adult

2012
Endoscopic evaluation of low-dose aspirin-induced gastric and duodenal ulcers during prophylaxis with lansoprazole.
    Hepato-gastroenterology, 2013, Volume: 60, Issue:124

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Comorbidity; Double-Blind Method; Duodenal Ulcer; Endoscopy, Gastrointestinal; Female; Humans; Lansoprazole; Male; Middle Aged; Prospective Studies; Stomach Ulcer; Treatment Outcome

2013
Effect of esomeprazole with/without acetylsalicylic acid, omeprazole and lansoprazole on pharmacokinetics and pharmacodynamics of clopidogrel in healthy volunteers.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2014, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Area Under Curve; Aspirin; Clopidogrel; Cross-Over Studies; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Esomeprazole; Female; Healthy Volunteers; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Platelet Aggregation; Proton Pump Inhibitors; Ticlopidine; Young Adult

2014
Prasugrel but not high dose clopidogrel overcomes the lansoprazole neutralizing effect of P2Y12 inhibition: Results of the randomized DOSAPI study.
    European journal of clinical pharmacology, 2014, Volume: 70, Issue:9

    Topics: Adult; Aged; Anti-Ulcer Agents; Aspirin; Clopidogrel; Coronary Artery Disease; Double-Blind Method; Drug Interactions; Female; Humans; Lansoprazole; Male; Middle Aged; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Thiophenes; Ticlopidine

2014
Vonoprazan prevents low-dose aspirin-associated ulcer recurrence: randomised phase 3 study.
    Gut, 2018, Volume: 67, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Double-Blind Method; Female; Follow-Up Studies; Gastrointestinal Hemorrhage; Humans; Japan; Lansoprazole; Male; Middle Aged; Peptic Ulcer; Pyrroles; Recurrence; Secondary Prevention; Sulfonamides; Treatment Outcome

2018
PRIMMO study protocol: a phase II study combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer.
    BMC cancer, 2019, May-28, Volume: 19, Issue:1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Aspirin; Chemoradiotherapy; Curcumin; Cyclophosphamide; Drug Repositioning; Endometrial Neoplasms; Female; Humans; Immunotherapy; Lansoprazole; Neoplasm Recurrence, Local; Sarcoma; Survival Analysis; Treatment Outcome; Uterine Cervical Neoplasms; Vitamin D

2019

Other Studies

30 other study(ies) available for aspirin and lansoprazole

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of different antisecretory drugs on gastric potential difference in the rat: comparison with sucralfate.
    Pharmacological research, 1998, Volume: 38, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Aspirin; Drug Interactions; Gastric Acid; Lansoprazole; Male; Nizatidine; Omeprazole; Proton Pump Inhibitors; Ranitidine; Rats; Rats, Wistar; Sucralfate

1998
Current approaches to reducing gastrointestinal toxicity of low-dose aspirin.
    The American journal of medicine, 2001, Jan-08, Volume: 110, Issue:1A

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Misoprostol; Omeprazole; Peptic Ulcer; Ranitidine

2001
Gastroprotective activity of oleanolic acid derivatives on experimentally induced gastric lesions in rats and mice.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Drug; Ethanol; Hydrochloric Acid; Lansoprazole; Ligation; Male; Mice; Molecular Structure; Oleanolic Acid; Omeprazole; Phytotherapy; Pylorus; Ranitidine; Rats; Rats, Sprague-Dawley; Solanaceae; Stomach Ulcer; Toxicity Tests, Acute

2002
Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin.
    The New England journal of medicine, 2002, Nov-14, Volume: 347, Issue:20

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Omeprazole; Peptic Ulcer; Proton Pump Inhibitors; Secondary Prevention

2002
Low-dose aspirin: protection from the panacea.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Omeprazole; Secondary Prevention; Ulcer

2002
An aspirin a day keeps the cardiologist away (but what about the gastroenterologist?).
    Gastroenterology, 2003, Volume: 124, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Aspirin; Dose-Response Relationship, Drug; Drug Administration Schedule; Gastrointestinal Diseases; Heart Diseases; Humans; Lansoprazole; Omeprazole; Secondary Prevention; Ulcer

2003
Disease-modifying anti-rheumatic drugs are only one of a number of potential causes of myelosuppression: a careful drug history is necessary to elucidate the cause of an adverse event.
    Rheumatology (Oxford, England), 2006, Volume: 45, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Infective Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Female; Humans; Lansoprazole; Methotrexate; Omeprazole; Pancytopenia

2006
[Gastric protection and treatment with low-dose aspirin].
    Medicina clinica, 2006, Feb-18, Volume: 126, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Cohort Studies; Controlled Clinical Trials as Topic; Fibrinolytic Agents; Gastrointestinal Hemorrhage; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Meta-Analysis as Topic; Odds Ratio; Omeprazole; Peptic Ulcer Hemorrhage; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Risk; Risk Factors; Stomach; Stomach Ulcer; Tablets, Enteric-Coated; Time Factors

2006
A majority of tube-fed patients are on medications that require special precautions.
    Age and ageing, 2010, Volume: 39, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aspirin; Enteral Nutrition; Humans; Lansoprazole; Laxatives; Medication Errors; Prednisolone; Prevalence

2010
Does long-term aspirin use have any effect on Helicobacter pylori eradication?
    The American journal of the medical sciences, 2011, Volume: 342, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Case-Control Studies; Clarithromycin; Drug Resistance, Microbial; Female; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Pilot Projects; Prospective Studies; Time Factors; Treatment Outcome

2011
Prevalence of gastroduodenal ulcers/erosions in patients taking low-dose aspirin with either 15 mg/day of lansoprazole or 40 mg/day of famotidine: the OITA-GF study 2.
    BMC research notes, 2013, Mar-26, Volume: 6

    Topics: Aged; Anti-Ulcer Agents; Aspirin; Cohort Studies; Cross-Sectional Studies; Drug Administration Schedule; Endoscopy; Famotidine; Female; Gastric Mucosa; Humans; Lansoprazole; Male; Middle Aged; Peptic Ulcer; Prevalence; Steroids

2013
Problem based review: The patient with a pyrexia of unknown origin.
    Acute medicine, 2013, Volume: 12, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Infective Agents; Anti-Inflammatory Agents; Aorta; Aortography; Arthralgia; Aspirin; Diagnosis, Differential; Female; Fever of Unknown Origin; Headache; Humans; Lansoprazole; Malaysia; Middle Aged; Multimodal Imaging; Positron-Emission Tomography; Prednisolone; Singapore; Takayasu Arteritis; Tomography, X-Ray Computed; Treatment Outcome

2013
Different Clopidogrel Response Elicited by Lansoprazole or Esomeprazole in Patients Undergoing Neurointervention with Dual Antiplatelet Therapy.
    Clinical drug investigation, 2019, Volume: 39, Issue:10

    Topics: Aged; Aged, 80 and over; Aspirin; Clopidogrel; Dual Anti-Platelet Therapy; Esomeprazole; Female; Humans; Lansoprazole; Male; Middle Aged; Neurosurgical Procedures; Platelet Aggregation Inhibitors; Proton Pump Inhibitors; Retrospective Studies; Thromboembolism

2019
What Is the Optimal Follow-up Time to Ascertain the Safety of Proton Pump Inhibitors?
    Gastroenterology, 2020, Volume: 158, Issue:4

    Topics: Aspirin; Follow-Up Studies; Humans; Lansoprazole; Proton Pump Inhibitors; Rivaroxaban

2020
Cost-Effectiveness of Vonoprazan Compared With Proton Pump Inhibitors in Patients Taking Low-Dose Aspirin for Secondary Prevention of Cardiovascular Events in Japan.
    Circulation journal : official journal of the Japanese Circulation Society, 2023, 01-25, Volume: 87, Issue:2

    Topics: Aged; Aspirin; Cardiovascular Diseases; Cost-Benefit Analysis; Esomeprazole; Gastrointestinal Hemorrhage; Humans; Japan; Lansoprazole; Proton Pump Inhibitors; Pyrroles; Secondary Prevention

2023
Adverse event profiles of microscopic colitis in the Japanese Adverse Drug Event Report (JADER) database.
    Scientific reports, 2022, 10-21, Volume: 12, Issue:1

    Topics: Adverse Drug Reaction Reporting Systems; Aspirin; Colitis, Microscopic; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Japan; Lansoprazole; Middle Aged; Nicorandil; United States

2022
Inappropriate proton pump inhibitor lansoprazole prescription in older adults hospitalized in long-term care unit.
    Irish journal of medical science, 2023, Volume: 192, Issue:4

    Topics: Aged; Aspirin; Humans; Inappropriate Prescribing; Lansoprazole; Long-Term Care; Proton Pump Inhibitors

2023