aspirin and ketanserin

aspirin has been researched along with ketanserin in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199010 (31.25)18.7374
1990's13 (40.63)18.2507
2000's4 (12.50)29.6817
2010's5 (15.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bochner, F; Duncan, EM; Lloyd, JV; Rodgers, SE; Vanags, DM1
Harrington, DP; Hollenberg, NK; Janicek, MJ; Meyerovitz, M1
al-Humayyd, MS; Mobarok Ali, AT1
Bauer, E; Lüscher, TF; Stulz, P; Turina, M; von Segesser, L; Yang, ZH1
Kinlough-Rathbone, RL; Packham, MA; Rand, ML; Ruben, DH1
Beetens, J; De Clerck, F; Janssen, PA; Loots, W; Somers, Y; Wouters, L; Wynants, J1
Kienast, J; Verstraete, M1
Awano, K; Fukuzaki, H; Yokoyama, M1
Völkl, KP1
Holmsen, H; Lie, RT; Thorsen, T1
Del Vecchio, PJ; Kaplan, JE; Malik, AB; Minnear, FL; Moon, DG; Shepard, JM; Sherman, PF; Weston, LK1
Hladovec, J2
David, JL1
Bondard, I; Duloroy, J; Fraitag, B; Gorin, NC1
Mizuno, R; Ohhashi, T1
Dondi, M; Pini, LA; Sandrini, M; Vitale, G1
Hata, H; Hirakawa, Y; Kuga, T; Ohara, Y; Takeshita, A; Tomoike, H1
Beaughard, M; Brasset, M; John, G; Massingham, R1
Bertolino, F; Fauré, P; John, GW; Valentin, JP; Vieu, S1
Ikomi, F; Ohhashi, T; Wang, JX1
Odendaal, HJ; Steyn, DW1
Brohard-Bohn, B; de Nucci, G; Lafay, M; Marcondes, S; Rendu, F1
Pini, LA; Sandrini, M; Vitale, G1
BLAUG, SM; RICH, AG1
Ahrens, I; Bode, C; Brandt, C; Duerschmied, D; Mauler, M; Moser, M; Weidner, S1

Reviews

1 review(s) available for aspirin and ketanserin

ArticleYear
Pharmacology of the interaction between platelets and vessel wall.
    Clinics in haematology, 1986, Volume: 15, Issue:2

    Topics: Animals; Aspirin; Blood Platelets; Blood Vessels; Dextrans; Diltiazem; Dipyridamole; Epoprostenol; Humans; Imidazoles; Ketanserin; Piperidines; Pyrazoles; Pyrazolones; Sulfinpyrazone; Sulfonamides; Thiophenes; Ticlopidine

1986

Trials

3 trial(s) available for aspirin and ketanserin

ArticleYear
Arterial response to ketanserin and aspirin in patients with advanced peripheral atherosclerosis.
    Investigative radiology, 1992, Volume: 27, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Arteries; Arteriosclerosis; Aspirin; Female; Humans; Ketanserin; Male; Middle Aged; Platelet Activation; Radiography; Vasoconstriction; Vasodilation

1992
Different interactions of platelets with arterial and venous coronary bypass vessels.
    Lancet (London, England), 1991, Apr-20, Volume: 337, Issue:8747

    Topics: Apyrase; Arginine; Aspirin; Blood Platelets; Coronary Artery Bypass; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Isometric Contraction; Ketanserin; Mammary Arteries; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Platelet Aggregation; Saphenous Vein; Thromboxane A2

1991
Randomised controlled trial of ketanserin and aspirin in prevention of pre-eclampsia.
    Lancet (London, England), 1997, Nov-01, Volume: 350, Issue:9087

    Topics: Adult; Antihypertensive Agents; Aspirin; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Ketanserin; Middle Aged; Platelet Aggregation Inhibitors; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Risk Factors; Serotonin Antagonists

1997

Other Studies

28 other study(ies) available for aspirin and ketanserin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Potentiation of ADP-induced aggregation in human platelet-rich plasma by 5-hydroxytryptamine and adrenaline.
    British journal of pharmacology, 1992, Volume: 106, Issue:4

    Topics: Adenosine Diphosphate; Adult; Aspirin; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Female; Humans; In Vitro Techniques; Ketanserin; Male; Platelet Aggregation; Serotonin; Yohimbine

1992
Enhancement of antithrombotic effect of aspirin by metoclopramide in rats.
    Thrombosis research, 1991, Feb-15, Volume: 61, Issue:4

    Topics: 5-Hydroxytryptophan; Administration, Oral; Animals; Aspirin; Benzamides; Body Temperature; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Drug Combinations; Drug Interactions; Female; Fibrinolytic Agents; Injections, Intravenous; Ketanserin; Metoclopramide; Rats; Receptors, Cell Surface; Thrombosis

1991
Effect of calcium concentration and inhibitors on the responses of platelets stimulated with collagen: contrast between human and rabbit platelets.
    Comparative biochemistry and physiology. A, Comparative physiology, 1991, Volume: 99, Issue:4

    Topics: Animals; Aspirin; Blood Platelets; Calcium; Cell Degranulation; Collagen; Cyclooxygenase Inhibitors; Cytosol; Humans; In Vitro Techniques; Indomethacin; Ketanserin; Kinetics; Rabbits; Thromboxane A2

1991
5-Hydroxytryptamine and arachidonic acid metabolites modulate extensive platelet activation induced by collagen in cats in vivo.
    British journal of pharmacology, 1990, Volume: 99, Issue:4

    Topics: Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspirin; Cats; Collagen; Cyclooxygenase Inhibitors; Female; Ketanserin; Male; Muscle, Smooth, Vascular; Pentanoic Acids; Platelet Activation; Pyridines; Receptors, Prostaglandin; Serotonin; Thromboxane-A Synthase

1990
Role of serotonin, histamine, and thromboxane A2 in platelet-induced contractions of coronary arteries and aortae from rabbits.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:5

    Topics: Animals; Aorta, Thoracic; Aspirin; Blood Platelets; Coronary Vessels; Diphenhydramine; Endothelium, Vascular; Female; Histamine; In Vitro Techniques; Isometric Contraction; Ketanserin; Male; Methysergide; Muscle Contraction; Muscle, Smooth, Vascular; Phentolamine; Rabbits; Serotonin; Thromboxane A2

1989
A sensitive in vivo platelet function test in rats based on intravenously injected collagenase.
    Haemostasis, 1989, Volume: 19, Issue:3

    Topics: Animals; Aspirin; Dipyridamole; Imidazoles; Indomethacin; Injections, Intravenous; Ketanserin; Microbial Collagenase; Mopidamol; Platelet Count; Platelet Function Tests; Rats; Rats, Inbred Strains

1989
Induction of platelet aggregation in vitro by microbubbles of nitrogen.
    Undersea biomedical research, 1989, Volume: 16, Issue:6

    Topics: Adenosine Diphosphate; Aspirin; Drug Synergism; Epinephrine; Gases; Humans; In Vitro Techniques; Indomethacin; Ketanserin; Nitrogen; Platelet Aggregation; Serotonin; Yohimbine

1989
Platelets decrease albumin permeability of pulmonary artery endothelial cell monolayers.
    Microvascular research, 1989, Volume: 37, Issue:3

    Topics: Albumins; Animals; Aspirin; Blood Platelets; Cells, Cultured; Endothelium, Vascular; Humans; In Vitro Techniques; Ketanserin; Permeability; Propranolol; Pulmonary Artery

1989
A sensitive model of venous thrombosis in rats.
    Thrombosis research, 1986, Sep-01, Volume: 43, Issue:5

    Topics: Animals; Anticoagulants; Aspirin; Dipyridamole; Disease Models, Animal; Female; Heparin; Ketanserin; Piperidines; Rats; Rats, Inbred Strains; Sulfinpyrazone; Thrombophlebitis; Time Factors

1986
Antithrombotics in view of thrombosis models.
    Thrombosis research, 1986, Sep-01, Volume: 43, Issue:5

    Topics: Animals; Anticoagulants; Arteries; Aspirin; Dipyridamole; Female; Hydroxyethylrutoside; Ketanserin; Piperidines; Pizotyline; Prenylamine; Rats; Rats, Inbred Strains; Sulfinpyrazone; Thrombophlebitis; Thrombosis

1986
[Mode of action and clinical evaluation of platelet aggregation inhibitors].
    Revue medicale de Liege, 1987, May-15, Volume: 42, Issue:10

    Topics: Aspirin; Cerebrovascular Disorders; Dipyridamole; Graft Occlusion, Vascular; Humans; Ketanserin; Myocardial Infarction; Platelet Aggregation; Sulfinpyrazone; Ticlopidine

1987
Effect of ketanserin on bleeding time: a comparison with aspirin.
    Thrombosis research, 1986, Oct-15, Volume: 44, Issue:2

    Topics: Adult; Aspirin; Bleeding Time; Blood Coagulation; Drug Therapy, Combination; Female; Humans; Ketanserin; Male; Platelet Function Tests

1986
5-Hydroxytryptamine-induced NO-dependent relaxation in isolated strips of monkey popliteal lymph nodes.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 2

    Topics: Animals; Arginine; Aspirin; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Ketanserin; Lymph Nodes; Macaca; Male; Methiothepin; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; omega-N-Methylarginine; Serotonin; Serotonin Receptor Agonists

1995
Effects of acetylsalicylic acid on serotonin brain receptor subtypes.
    General pharmacology, 1995, Volume: 26, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics; Animals; Aspirin; Brain Chemistry; Cerebral Cortex; Ketanserin; Male; Membranes; Pons; Rats; Rats, Wistar; Receptors, Serotonin

1995
Inhibitory effects of heparin, aspirin and ketanserin on coronary artery vasoconstriction after arterial balloon injury in hypercholesterolemic miniature pigs.
    Journal of the American College of Cardiology, 1993, Volume: 22, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Animals; Aspirin; Blood Platelets; Coronary Vessels; Drug Interactions; Heparin; Hypercholesterolemia; Ketanserin; Male; Random Allocation; Swine; Swine, Miniature; Vasoconstriction

1993
Failure of calcium channel blockade to reduce platelet-mediated cyclic flow variations in dogs with coronary stenosis and endothelial injury.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:4

    Topics: Animals; Aspirin; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; Disease Models, Animal; Dogs; Endothelium, Vascular; Female; Heart Block; Infusions, Intravenous; Ketanserin; Male; Nifedipine; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Vasodilator Agents; Verapamil

1995
Differential involvement of serotonin 2A/C and thromboxane A2/prostanoid receptors in high- vs. low-shear rate arterial thrombosis in rabbits.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: Animals; Arteriovenous Shunt, Surgical; Aspirin; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Carotid Arteries; Carotid Stenosis; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart Rate; Hemodynamics; Hydrazines; Jugular Veins; Ketanserin; Male; Oxadiazoles; Piperazines; Platelet Aggregation; Prazosin; Rabbits; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Prostaglandin; Receptors, Serotonin; Receptors, Thromboxane; Ritanserin; Serotonin Antagonists; Stress, Mechanical

1997
5-Hydroxytryptamine-induced endothelium-dependent and -independent relaxations in isolated dog anterior spinal small arteries.
    Canadian journal of physiology and pharmacology, 1997, Volume: 75, Issue:5

    Topics: Animals; Arteries; Aspirin; Dogs; Endothelium, Vascular; Epoprostenol; Female; Fibrinolytic Agents; Indoles; Ketanserin; Male; Methiothepin; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Serotonin; Serotonin Antagonists; Tropisetron

1997
Platelets induce human umbilical vein endothelial cell proliferation through P-selectin.
    Life sciences, 2000, Mar-31, Volume: 66, Issue:19

    Topics: Aspirin; Blood Platelets; Cell Adhesion; Cell Division; Cell Line; Endothelium, Vascular; Female; Humans; Ketanserin; Mitogens; P-Selectin; Platelet Aggregation Inhibitors; Pregnancy; Serotonin; Suramin; Thrombin; Thymidine; Umbilical Veins

2000
Central antinociceptive activity of acetylsalicylic acid is modulated by brain serotonin receptor subtypes.
    Pharmacology, 2002, Volume: 65, Issue:4

    Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Aspirin; Binding, Competitive; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Ketanserin; Male; Ondansetron; Pain Threshold; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT3; Serotonin Antagonists

2002
INTERACTION BETWEEN POLY-N-VINYL-5-METHYL-2-OXAZOLIDINONE AND CERTAIN PHARMACEUTICALS IN AQUEOUS SOLUTION.
    Journal of pharmaceutical sciences, 1965, Volume: 54

    Topics: Aspirin; Barbiturates; Benzoates; Chemistry, Pharmaceutical; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Indoles; Ketanserin; Macromolecular Substances; Methylprednisolone; Oxazoles; Oxazolidinones; Polymers; Research; Salicylic Acid; Sulfonamides; Xanthines

1965
Serotonin antagonism improves platelet inhibition in clopidogrel low-responders after coronary stent placement: an in vitro pilot study.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Aged; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Female; Humans; In Vitro Techniques; Ketanserin; Light; Male; Middle Aged; Myocardial Infarction; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin; Serotonin Antagonists; Stents; Ticlopidine; Treatment Outcome

2012