aspirin and isradipine

aspirin has been researched along with isradipine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (58.82)18.2507
2000's4 (23.53)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Angelberger, P; Gerakakis, A; Keiler, A; Lupattelli, G; Pirich, C; Sinzinger, H; Virgolini, I1
Angelberger, P; Keiler, A; Lupattelli, G; Molinari, E; O'Grady, J; Sinzinger, H; Virgolini, I1
Fitscha, P; Keiler, A; O'Grady, J; Rauscha, F; Sinzinger, H2
Keiler, A; O'Grady, J; Sinzinger, H1
Fetkovska, N; Jakubovska, Z; Oravcova, J; Tison, P; Ulicna, L2
Rogatti, W; Sinzinger, H1
Fetkovska, N; Jakubovska, Z; Oravcova, J; Tison, P; Trnovec, T; Ulicna, L1
Belenkov, IuN; Chazova, IE; Lazutkina, VK; Martyniuk, TV; Masenko, VP1

Reviews

1 review(s) available for aspirin and isradipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for aspirin and isradipine

ArticleYear
Effects of dihydropyridines and their combination with aspirin on blood pressure and circadian platelet activity in patients with essential hypertension.
    American journal of hypertension, 1994, Volume: 7, Issue:7 Pt 2

    Topics: Adult; Aspirin; Blood Platelets; Blood Pressure; Circadian Rhythm; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Isradipine; Male; Middle Aged; Nitrendipine

1994
Treatment of hypertension with dihydropyridine calcium antagonists and aspirin.
    Blood pressure. Supplement, 1994, Volume: 1

    Topics: Adult; Aspirin; Blood Platelets; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Isradipine; Male; Middle Aged; Nitrendipine

1994
Treatment of hypertension with calcium antagonists and aspirin. Effects on 24-h platelet activity.
    American journal of hypertension, 1993, Volume: 6, Issue:3 Pt 2

    Topics: Adult; Aspirin; Circadian Rhythm; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Isradipine; Male; Middle Aged; Nitrendipine; Platelet Aggregation; Treatment Outcome

1993

Other Studies

13 other study(ies) available for aspirin and isradipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Concomitant aspirin treatment abolishes the antiatherosclerotic effects of the calcium channel blocker isradipine mediated by PGI2.
    Agents and actions. Supplements, 1992, Volume: 37

    Topics: Animals; Aorta, Abdominal; Arteriosclerosis; Aspirin; Calcium Channel Blockers; Cholesterol; Dihydropyridines; Epoprostenol; Humans; Hypercholesterolemia; Isradipine; Kinetics; Lipid Metabolism; Lipoproteins, LDL; Male; Rabbits

1992
Aspirin abolishes the decreased low-density lipoprotein (LDL) entry into the rabbit arterial wall induced by the calcium channel blocker isradipine.
    Eicosanoids, 1992, Volume: 5, Issue:1

    Topics: Animals; Aspirin; Calcium Channel Blockers; Cholesterol; Endothelium, Vascular; Epoprostenol; Isradipine; Lipoproteins, LDL; Male; Rabbits

1992
The diminished extracellular matrix production induced by isradipine, a calcium channel blocker, is completely abolished by cyclooxygenase inhibition.
    Prostaglandins, leukotrienes, and essential fatty acids, 1992, Volume: 45, Issue:4

    Topics: Animals; Arteriosclerosis; Aspirin; Calcium Channel Blockers; Collagen; Cyclooxygenase Inhibitors; Dihydropyridines; Drug Interactions; Epoprostenol; Extracellular Matrix; Glycosaminoglycans; Isradipine; Male; Rabbits

1992
Arterial wall rather than platelets is responsible for diminished thrombogenicity during isradipine therapy.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:3

    Topics: Animals; Arteries; Aspirin; Blood Platelets; Endothelium, Vascular; Epoprostenol; Humans; In Vitro Techniques; Indium Radioisotopes; Isradipine; Male; Perfusion; Rabbits; Thrombosis; Thromboxane B2

1995
Prostaglandins and arterial wall lipid metabolism--in vitro, ex-vivo and in-vivo radioisotopic studies.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1994, Volume: 45, Issue:1

    Topics: Alprostadil; Animals; Arteries; Aspirin; Cholesterol; Cyclic AMP; Epoprostenol; Humans; In Vitro Techniques; Iodine Radioisotopes; Isradipine; Kinetics; Lipid Metabolism; Lipids; Lipoproteins, LDL; Male; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E, Synthetic; Rabbits

1994
Isradipine inhibits mitotic and proliferative activity in the arterial wall.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1994, Volume: 46, Issue:1

    Topics: Animals; Arteries; Aspirin; Cell Division; Cholesterol; Desoxycorticosterone; Epoprostenol; Humans; Isradipine; Male; Mitosis; Rabbits; Thymidine

1994
[The use of aspirin in patients with primary pulmonary hypertension].
    Terapevticheskii arkhiv, 1998, Volume: 70, Issue:8

    Topics: Adult; Alprostadil; Aspirin; Calcium Channel Blockers; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension, Pulmonary; Isradipine; Male; Platelet Aggregation Inhibitors; Time Factors; Vasodilator Agents

1998