aspirin and isoxazoles

aspirin has been researched along with isoxazoles in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19904 (21.05)18.7374
1990's0 (0.00)18.2507
2000's13 (68.42)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diamantis, W; Ludwig, BJ; Sofia, RD1
Sofia, RD1
DiPasquale, G; Rassaert, C; Tripp, L; Welaj, P1
Bloss, JL; Hammond, DL1
Crain, EJ; Knabb, RM; Meade, RP; Quan, ML; Slee, AM; Watson, CA; Wexler, RR; Wong, PC; Wright, MR1
Ouellet, M; Percival, MD; Riendeau, D1
Cain, VA; Ebling, W; Fossler, MJ; Kornhauser, DM; Ma, S; Mondick, JT; Pieniaszek, HJ; Sy, SK1
Barbera, FA; Dorsam, RT; Feuerstein, GZ; Friedman, SM; Gibbs, S; Lauver, A; Savion, N; Varon, D; Wang, H; Wang, X1
Gurbel, PA; Malinin, AI; O'connor, CM; Serebruany, VL1
Bulut, D; Hanefeld, C; Koll, R; Liaghat, S; Miebach, T; Mügge, A1
Amano, H; Hayashi, I; Inukai, M; Kamata, M; Kitasato, H; Majima, M; Yoshida, S; Yoshimura, H1
Eisen, GM; Goldstein, JL; Hanna, DB; Rublee, DA1
Bozarth, JM; Feuerstein, GZ; Mousa, SA; Seiffert, D1
Borgdorff, P; Paulus, WJ; Tangelder, GJ1
Crain, EJ; Knabb, RM; Lam, PY; Quan, ML; Watson, CA; Wexler, RR; Wong, PC1
Boutary, M; Dorr, LD; Long, WT; Raya, J; Sirianni, LE1
Herrndobler, F; Koppert, W; Maihöfner, C; Ringler, R1
Bartra, J; Muñoz-Cano, R; Picado, C; Roca, J; Sánchez-López, J; Serrano, C; Valero, A1
Armstrong, PC; Emerson, M; Kirkby, NS; Mitchell, JA; Warner, TD; Zain, ZN1

Reviews

1 review(s) available for aspirin and isoxazoles

ArticleYear
Meta-analysis: upper gastrointestinal tolerability of valdecoxib, a cyclooxygenase-2-specific inhibitor, compared with nonspecific nonsteroidal anti-inflammatory drugs among patients with osteoarthritis and rheumatoid arthritis.
    Alimentary pharmacology & therapeutics, 2005, Mar-01, Volume: 21, Issue:5

    Topics: Abdominal Pain; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase Inhibitors; Dyspepsia; Female; Humans; Isoxazoles; Male; Middle Aged; Nausea; Osteoarthritis; Randomized Controlled Trials as Topic; Sulfonamides

2005

Trials

7 trial(s) available for aspirin and isoxazoles

ArticleYear
Safety, tolerability, pharmacokinetics, and time course of pharmacologic response of the active metabolite of roxifiban, XV459, a glycoprotein IIb/IIIa antagonist, following oral administration in healthy volunteers.
    Journal of clinical pharmacology, 2002, Volume: 42, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Amidines; Amino Acids; Area Under Curve; Aspirin; Bleeding Time; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Humans; Hydrolysis; Isoxazoles; Male; Middle Aged; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs; Time Factors

2002
Effects of roxifiban on platelet aggregation and major receptor expression in patients with coronary artery disease for the Roxifiban Oral Compound Kinetics Evaluation Trial-I (ROCKET-I Platelet Substudy).
    American heart journal, 2003, Volume: 146, Issue:1

    Topics: Amidines; Aspirin; Coronary Disease; Coronary Thrombosis; Double-Blind Method; Female; Flow Cytometry; Humans; Isoxazoles; Male; Middle Aged; Platelet Aggregation; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Statistics, Nonparametric; Thrombolytic Therapy

2003
Selective cyclo-oxygenase-2 inhibition with parecoxib acutely impairs endothelium-dependent vasodilatation in patients with essential hypertension.
    Journal of hypertension, 2003, Volume: 21, Issue:9

    Topics: Acetylcholine; Adult; Aged; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Forearm; Humans; Hypertension; Isoenzymes; Isoxazoles; Lysine; Male; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; Regional Blood Flow; Vasodilation; Vasodilator Agents

2003
Using thrombelastography to determine the efficacy of the platelet glycoprotein IIb/IIIa antagonist, roxifiban, on platelet/fibrin-mediated clot dynamics in humans.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2005, Volume: 16, Issue:3

    Topics: Amidines; Aspirin; Blood Coagulation; Calcium Chloride; Cross-Over Studies; Fibrin; Humans; Isoxazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Reference Values; Thrombelastography

2005
Multimodal analgesia without parenteral narcotics for total knee arthroplasty.
    The Journal of arthroplasty, 2008, Volume: 23, Issue:4

    Topics: Administration, Oral; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; Aspirin; Catheters, Indwelling; Celecoxib; Drug Administration Schedule; Drug Therapy, Combination; Femoral Nerve; Hip Joint; Humans; Injections, Intra-Articular; Isoxazoles; Ketorolac; Nerve Block; Pain Measurement; Pain, Postoperative; Prospective Studies; Pyrazoles; Ropivacaine; Sulfonamides

2008
[Modulation of cortical pain processing by cyclooxygenase inhibition: a functional MRI study].
    Schmerz (Berlin, Germany), 2009, Volume: 23, Issue:2

    Topics: Acute Disease; Adult; Analgesics; Aspirin; Brain Mapping; Cerebral Cortex; Cyclooxygenase Inhibitors; Dominance, Cerebral; Double-Blind Method; Female; Frontal Lobe; Gyrus Cinguli; Humans; Hyperalgesia; Image Processing, Computer-Assisted; Isoxazoles; Magnetic Resonance Imaging; Male; Motor Cortex; Pain; Pain Measurement; Pain Threshold; Parietal Lobe; Psychophysics; Somatosensory Cortex

2009
Safety of parecoxib in asthmatic patients with aspirin-exacerbated respiratory disease.
    International archives of allergy and immunology, 2011, Volume: 156, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma, Aspirin-Induced; Cyclooxygenase 2 Inhibitors; Female; Forced Expiratory Volume; Humans; Isoxazoles; Leukotriene E4; Male; Middle Aged; Nasal Provocation Tests

2011

Other Studies

11 other study(ies) available for aspirin and isoxazoles

ArticleYear
Pharmacological properties of 2,3-dihydro-9H-isoxazolo [3,2-b] quinazolin-9-one (W-2429. Part 1: Analgesic, antipyretic and antiedema activity.
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:4

    Topics: Administration, Oral; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Body Temperature; Dextropropoxyphene; Drug Interactions; Drug Tolerance; Edema; Fever; Humans; Injections, Intravenous; Isoxazoles; Lethal Dose 50; Male; Mice; Narcotic Antagonists; Oxazoles; Quinazolines; Rats; Substance-Related Disorders; Time Factors

1977
Comparative antiphlogistic activity of meseclazone, 5-chlorosalicylic acid, acetylsalicylic acid, phenylbutazone, indomethacin and hydrocortisone in various rat paw edema models.
    Pharmacology, 1978, Volume: 16, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Benzoxazines; Drug Evaluation, Preclinical; Edema; Hydrocortisone; Indomethacin; Isoxazoles; Male; Oxazines; Phenylbutazone; Rats; Salicylates

1978
Anti-inflammatory activity of isoxicam in combination with aspirin or D-propoxyphene.
    Agents and actions, 1976, Volume: 6, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Body Weight; Dextropropoxyphene; Drug Therapy, Combination; Isoxazoles; Male; Organ Size; Oxazoles; Piroxicam; Rats; Thiazines

1976
Shock titration in the rhesus monkey: effects of opiate and nonopiate analgesics.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2

    Topics: Administration, Oral; Analgesics; Animals; Aspirin; Codeine; Diazepam; Dose-Response Relationship, Drug; Electroshock; Ibuprofen; Injections, Intramuscular; Isoxazoles; Male; Morphine; Narcotics; Reaction Time; Sensory Thresholds; Time Factors

1985
Nonpeptide factor Xa inhibitors II. Antithrombotic evaluation in a rabbit model of electrically induced carotid artery thrombosis.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1

    Topics: Animals; Aspirin; Blood Pressure; Boron Compounds; Carotid Artery Thrombosis; Factor Xa Inhibitors; Fibrinolytic Agents; Heart Rate; Heparin; Humans; Isoxazoles; Male; Microscopy, Electron, Scanning; Oligopeptides; Platelet Aggregation; Rabbits; Recombinant Proteins; Tetrazoles

2000
A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirin.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Dec-04, Volume: 98, Issue:25

    Topics: Acetylation; Animals; Aspirin; Blood Platelets; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etoricoxib; Humans; Ibuprofen; In Vitro Techniques; Isoenzymes; Isoxazoles; Lactones; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyridines; Sheep; Sulfonamides; Sulfones

2001
Comparative analysis of various platelet glycoprotein IIb/IIIa antagonists on shear-induced platelet activation and adhesion.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Abciximab; Alanine; Amidines; Analysis of Variance; Antibodies, Monoclonal; Anticoagulants; Aspirin; Cell Aggregation; Dose-Response Relationship, Drug; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Isoxazoles; Peptides; Platelet Activation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Rheology; Shear Strength; Temperature; Tirofiban; Tyrosine

2002
COX-2/VEGF-dependent facilitation of tumor-associated angiogenesis and tumor growth in vivo.
    Laboratory investigation; a journal of technical methods and pathology, 2003, Volume: 83, Issue:10

    Topics: Animals; Antibodies, Blocking; Aspirin; Benzenesulfonates; Carcinoma, Lewis Lung; Cyclooxygenase Inhibitors; Disease Models, Animal; Endothelial Growth Factors; Intercellular Signaling Peptides and Proteins; Isoxazoles; Lymphokines; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neovascularization, Pathologic; Nitrobenzenes; Oxazoles; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sarcoma 180; Sulfonamides; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2003
Cyclooxygenase-2 inhibitors enhance shear stress-induced platelet aggregation.
    Journal of the American College of Cardiology, 2006, Aug-15, Volume: 48, Issue:4

    Topics: Animals; Aspirin; Clopidogrel; Coronary Artery Bypass; Coronary Stenosis; Cyclooxygenase Inhibitors; Isoxazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Risk Factors; Shear Strength; Thrombosis; Ticlopidine

2006
Razaxaban, a direct factor Xa inhibitor, in combination with aspirin and/or clopidogrel improves low-dose antithrombotic activity without enhancing bleeding liability in rabbits.
    Journal of thrombosis and thrombolysis, 2007, Volume: 24, Issue:1

    Topics: Animals; Aspirin; Blood Coagulation; Clopidogrel; Disease Models, Animal; Drug Therapy, Combination; Factor Xa; Fibrinolytic Agents; Hemorrhage; Hemostasis; Isoxazoles; Male; Platelet Aggregation; Pyrazoles; Rabbits; Thrombosis; Ticlopidine

2007
Thrombosis is reduced by inhibition of COX-1, but unaffected by inhibition of COX-2, in an acute model of platelet activation in the mouse.
    PloS one, 2011, Volume: 6, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aspirin; Collagen; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Disease Models, Animal; Isoxazoles; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Thrombosis

2011